Mutations in the PTCH (PTCH1) gene are the underlying cause of nevoid basal cell carcinoma syndrome (NBCCS), and are also found in many different sporadic ...
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Protein patched homolog 1 is a protein that is the member of the patched family and in humans is encoded by the PTCH1 gene.
The PTCH gene encodes a transmembrane protein that acts in opposition to the Hedgehog signaling protein, controlling cell fates, patterning, and growth in ...
Oct 1, 2012 · Based on its role in preventing cells from proliferating in an uncontrolled way, PTCH1 is called a tumor suppressor gene. Health Conditions ...
Our results show that all major subtypes of odontogenic cysts might express PTCH. Still 88% of odontogenic keratocysts are PTCH positive, the percentage drops ...
(1996) identified a 9-bp insertion (CCGAATATC) in the PTCH gene. The heterozygous mutation results in the insertion of proline, asparagine, and isoleucine after ...
PTCH1 (Patched 1) is a Protein Coding gene. Diseases associated with PTCH1 include Basal Cell Nevus Syndrome 1 and Holoprosencephaly 7. Among its related ...
The PTCH1 gene provides instructions for producing the patched-1 protein, which functions as a receptor. Receptor proteins have specific sites into which ...
The PTCH1 gene encodes a transmembrane protein that functions as a receptor for the secreted hedgehog signaling molecules including sonic hedgehog (SHH). In the ...