CA2082427A1 - Prosthetic intervertebral disc - Google Patents

Prosthetic intervertebral disc

Info

Publication number
CA2082427A1
CA2082427A1 CA2082427A CA2082427A CA2082427A1 CA 2082427 A1 CA2082427 A1 CA 2082427A1 CA 2082427 A CA2082427 A CA 2082427A CA 2082427 A CA2082427 A CA 2082427A CA 2082427 A1 CA2082427 A1 CA 2082427A1
Authority
CA
Canada
Prior art keywords
intervertebral disc
matrix
prosthetic intervertebral
scaffold
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2082427A
Other languages
French (fr)
Other versions
CA2082427C (en
Inventor
Kevin R. Stone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regen Biologics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2082427A1 publication Critical patent/CA2082427A1/en
Application granted granted Critical
Publication of CA2082427C publication Critical patent/CA2082427C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/38Joints for elbows or knees
    • A61F2/3872Meniscus for implantation between the natural bone surfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30907Nets or sleeves applied to surface of prostheses or in cement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30965Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/38Joints for elbows or knees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • A61F2002/30131Rounded shapes, e.g. with rounded corners horseshoe- or crescent- or C-shaped or U-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30205Three-dimensional shapes conical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/3023Three-dimensional shapes cylindrical wedge-shaped cylinders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30721Accessories
    • A61F2/30734Modular inserts, sleeves or augments, e.g. placed on proximal part of stem for fixation purposes or wedges for bridging a bone defect
    • A61F2002/30736Augments or augmentation pieces, e.g. wedges or blocks for bridging a bone defect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • A61F2002/30766Scaffolds for cartilage ingrowth and regeneration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082Grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A61F2002/30879Ribs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30904Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves serrated profile, i.e. saw-toothed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30942Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/30957Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using a positive or a negative model, e.g. moulds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4274Distal carpal row, i.e. bones adjacent the metacarpal bones
    • A61F2002/4276Trapezium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4274Distal carpal row, i.e. bones adjacent the metacarpal bones
    • A61F2002/4279Trapezoid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4274Distal carpal row, i.e. bones adjacent the metacarpal bones
    • A61F2002/4282Capitate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4274Distal carpal row, i.e. bones adjacent the metacarpal bones
    • A61F2002/4284Hamate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4287Proximal carpal row, i.e. bones adjacent the radius and the ulna
    • A61F2002/4289Scaphoid or navicular bone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4287Proximal carpal row, i.e. bones adjacent the radius and the ulna
    • A61F2002/4292Lunate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4287Proximal carpal row, i.e. bones adjacent the radius and the ulna
    • A61F2002/4294Triquetrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4261Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for wrists
    • A61F2002/4271Carpal bones
    • A61F2002/4287Proximal carpal row, i.e. bones adjacent the radius and the ulna
    • A61F2002/4297Pisiform bone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0013Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0067Three-dimensional shapes conical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof

Abstract

A prosthetic intervertebral disc is disclosed which can be implanted in the human skeleton, and which can act as a scaffold for regrowth of intervertebral disc material. The disc includes a dry, porous, volume matrix of biocompatible and bioresorbable fibers which may be interspersed with glyscosaminoglycan molecules. The matrix is adapted to have in vivo an outer surface contour substantially the same as that of a natural intervertebral disc, whereby said matrix establishes an at least partially bioresorbable scaffold adapted for ingrowth of intervertebral fibrochondrocytes. Cross-links may be provided by a portion of the GAG molecules.
CA002082427A 1990-05-07 1991-05-06 Prosthetic intervertebral disc Expired - Lifetime CA2082427C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US520,027 1990-05-07
US07/520,027 US5108438A (en) 1989-03-02 1990-05-07 Prosthetic intervertebral disc
PCT/US1991/003106 WO1991016867A1 (en) 1990-05-07 1991-05-06 Prosthetic intervertebral disc

Publications (2)

Publication Number Publication Date
CA2082427A1 true CA2082427A1 (en) 1991-11-08
CA2082427C CA2082427C (en) 2000-10-31

Family

ID=24070896

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002082427A Expired - Lifetime CA2082427C (en) 1990-05-07 1991-05-06 Prosthetic intervertebral disc

Country Status (8)

Country Link
US (1) US5108438A (en)
EP (1) EP0527936B1 (en)
JP (1) JP3162375B2 (en)
AT (1) ATE155668T1 (en)
AU (1) AU647144B2 (en)
CA (1) CA2082427C (en)
DE (1) DE69126971T2 (en)
WO (1) WO1991016867A1 (en)

Families Citing this family (279)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5263984A (en) * 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5735902A (en) * 1987-07-20 1998-04-07 Regen Biologics, Inc. Hand implant device
US5269785A (en) * 1990-06-28 1993-12-14 Bonutti Peter M Apparatus and method for tissue removal
US6503277B2 (en) * 1991-08-12 2003-01-07 Peter M. Bonutti Method of transplanting human body tissue
DE4220218C2 (en) * 1992-06-20 1994-09-22 S & G Implants Gmbh Implant with an open-cell or open-pore metal structure
TW335351B (en) * 1993-08-31 1998-07-01 Depuy Inc Orthopaedic appliance, absorbable orthopaedic appliance, and method for forming an orthopaedic appliance
US5514180A (en) * 1994-01-14 1996-05-07 Heggeness; Michael H. Prosthetic intervertebral devices
CA2183962A1 (en) * 1994-03-22 1995-09-28 Paul D. Kemp Three-dimensional bioremodelable collagen fabrics
US5571189A (en) * 1994-05-20 1996-11-05 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
US5674296A (en) 1994-11-14 1997-10-07 Spinal Dynamics Corporation Human spinal disc prosthesis
AU746813B2 (en) * 1994-11-15 2002-05-02 Kenton W. Gregory Prosthetic device and process of production
US5713374A (en) * 1995-02-10 1998-02-03 The Hospital For Joint Diseases Orthopaedic Institute Fixation method for the attachment of wound repair materials to cartilage defects
US6080194A (en) * 1995-02-10 2000-06-27 The Hospital For Joint Disease Orthopaedic Institute Multi-stage collagen-based template or implant for use in the repair of cartilage lesions
US6262255B1 (en) 1995-04-05 2001-07-17 Biomm, Inc. Non-immunogenic, biocompatible macromolecular membrane compositions, and methods for making them
US5645597A (en) * 1995-12-29 1997-07-08 Krapiva; Pavel I. Disc replacement method and apparatus
US5865845A (en) * 1996-03-05 1999-02-02 Thalgott; John S. Prosthetic intervertebral disc
US5964807A (en) * 1996-08-08 1999-10-12 Trustees Of The University Of Pennsylvania Compositions and methods for intervertebral disc reformation
GB9704749D0 (en) * 1997-03-07 1997-04-23 Univ London Tissue Implant
DE19710392C1 (en) * 1997-03-13 1999-07-01 Haehnel Michael Slipped disc implant comprises an extensible, hinged or wound body
US6017366A (en) * 1997-04-18 2000-01-25 W. L. Gore & Associates, Inc. Resorbable interposition arthroplasty implant
GB9713330D0 (en) * 1997-06-25 1997-08-27 Bridport Gundry Plc Surgical implant
US6241771B1 (en) * 1997-08-13 2001-06-05 Cambridge Scientific, Inc. Resorbable interbody spinal fusion devices
EP0896825B1 (en) * 1997-08-14 2002-07-17 Sulzer Innotec Ag Composition and device for in vivo cartilage repair comprising nanocapsules with osteoinductive and/or chondroinductive factors
AT405237B (en) 1997-08-28 1999-06-25 Ronald J Dr Sabitzer SPINE PROSTHESIS
US6482233B1 (en) 1998-01-29 2002-11-19 Synthes(U.S.A.) Prosthetic interbody spacer
US6241769B1 (en) 1998-05-06 2001-06-05 Cortek, Inc. Implant for spinal fusion
US6296664B1 (en) 1998-06-17 2001-10-02 Surgical Dynamics, Inc. Artificial intervertebral disc
US6086593A (en) 1998-06-30 2000-07-11 Bonutti; Peter M. Method and apparatus for use in operating on a bone
US7147665B1 (en) 1998-07-22 2006-12-12 Sdgi Holdings, Inc. Threaded cylindrical multidiscoid single or multiple array disc prosthesis
US6099531A (en) * 1998-08-20 2000-08-08 Bonutti; Peter M. Changing relationship between bones
CA2342633C (en) * 1998-09-04 2007-11-13 Spinal Dynamics Corporation Peanut spectacle multi discoid thoraco-lumbar disc prosthesis
DE19855890A1 (en) * 1998-12-03 2000-06-08 Nerlich Michael Porous composite matrix, its production and use
US6206923B1 (en) * 1999-01-08 2001-03-27 Sdgi Holdings, Inc. Flexible implant using partially demineralized bone
CA2363254C (en) 1999-03-07 2009-05-05 Discure Ltd. Method and apparatus for computerized surgery
US20070038231A1 (en) * 1999-05-28 2007-02-15 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US7273497B2 (en) * 1999-05-28 2007-09-25 Anova Corp. Methods for treating a defect in the annulus fibrosis
US6969404B2 (en) * 1999-10-08 2005-11-29 Ferree Bret A Annulus fibrosis augmentation methods and apparatus
US20060247665A1 (en) * 1999-05-28 2006-11-02 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US6419704B1 (en) 1999-10-08 2002-07-16 Bret Ferree Artificial intervertebral disc replacement methods and apparatus
US6652872B2 (en) 1999-07-06 2003-11-25 Ramat At Tel Aviv University Ltd. Scaffold formed of tissue treated to eliminate cellular and cytosolic elements
US6632651B1 (en) 1999-07-06 2003-10-14 Ramot At Tel Aviv University Ltd. Tissue maintenance system that applies rhythmic pulses of pressure
US7435260B2 (en) * 1999-08-13 2008-10-14 Ferree Bret A Use of morphogenetic proteins to treat human disc disease
US6685695B2 (en) * 1999-08-13 2004-02-03 Bret A. Ferree Method and apparatus for providing nutrition to intervertebral disc tissue
US6793677B2 (en) * 1999-08-13 2004-09-21 Bret A. Ferree Method of providing cells and other biologic materials for transplantation
US7201776B2 (en) * 1999-10-08 2007-04-10 Ferree Bret A Artificial intervertebral disc replacements with endplates
US6755863B2 (en) * 1999-10-08 2004-06-29 Bret A. Ferree Rotator cuff repair using engineered tissues
US6454804B1 (en) 1999-10-08 2002-09-24 Bret A. Ferree Engineered tissue annulus fibrosis augmentation methods and apparatus
WO2009033100A1 (en) 2007-09-07 2009-03-12 Intrinsic Therapeutics, Inc. Bone anchoring systems
US6425919B1 (en) 1999-08-18 2002-07-30 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US6936072B2 (en) * 1999-08-18 2005-08-30 Intrinsic Therapeutics, Inc. Encapsulated intervertebral disc prosthesis and methods of manufacture
CA2425951C (en) 1999-08-18 2008-09-16 Intrinsic Therapeutics, Inc. Devices and method for nucleus pulposus augmentation and retention
US7507243B2 (en) 1999-08-18 2009-03-24 Gregory Lambrecht Devices and method for augmenting a vertebral disc
US7972337B2 (en) 2005-12-28 2011-07-05 Intrinsic Therapeutics, Inc. Devices and methods for bone anchoring
US7717961B2 (en) 1999-08-18 2010-05-18 Intrinsic Therapeutics, Inc. Apparatus delivery in an intervertebral disc
US8323341B2 (en) 2007-09-07 2012-12-04 Intrinsic Therapeutics, Inc. Impaction grafting for vertebral fusion
US7553329B2 (en) * 1999-08-18 2009-06-30 Intrinsic Therapeutics, Inc. Stabilized intervertebral disc barrier
WO2004100841A1 (en) 1999-08-18 2004-11-25 Intrinsic Therapeutics, Inc. Devices and method for augmenting a vertebral disc nucleus
US7220281B2 (en) * 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
US7998213B2 (en) 1999-08-18 2011-08-16 Intrinsic Therapeutics, Inc. Intervertebral disc herniation repair
US6783546B2 (en) * 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6648920B2 (en) * 1999-10-08 2003-11-18 Bret A. Ferree Natural and synthetic supplements to engineered annulus and disc tissues
US6645247B2 (en) * 1999-10-08 2003-11-11 Bret A. Ferree Supplementing engineered annulus tissues with autograft of allograft tendons
US7201774B2 (en) * 1999-10-08 2007-04-10 Ferree Bret A Artificial intervertebral disc replacements incorporating reinforced wall sections
US20030004574A1 (en) * 1999-10-08 2003-01-02 Ferree Bret A. Disc and annulus augmentation using biologic tissue
US20030026788A1 (en) * 1999-10-08 2003-02-06 Ferree Bret A. Use of extracellular matrix tissue to preserve cultured cell phenotype
US7060100B2 (en) * 1999-10-08 2006-06-13 Ferree Bret A Artificial disc and joint replacements with modular cushioning components
US20040186573A1 (en) * 1999-10-08 2004-09-23 Ferree Bret A. Annulus fibrosis augmentation methods and apparatus
US20040172019A1 (en) * 1999-10-08 2004-09-02 Ferree Bret A. Reinforcers for artificial disc replacement methods and apparatus
US6648919B2 (en) * 1999-10-14 2003-11-18 Bret A. Ferree Transplantation of engineered meniscus tissue to the intervertebral disc
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
WO2001028464A1 (en) 1999-10-20 2001-04-26 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US20030153976A1 (en) 1999-10-20 2003-08-14 Cauthen Joseph C. Spinal disc annulus reconstruction method and spinal disc annulus stent
EP1974698A3 (en) 1999-10-20 2009-01-28 Anulex Technologies, Inc. Spinal disc annulus stent
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
WO2001045577A2 (en) * 1999-12-06 2001-06-28 Sdgi Holdings, Inc. Intervertebral disc treatment devices and methods
US6740093B2 (en) * 2000-02-28 2004-05-25 Stephen Hochschuler Method and apparatus for treating a vertebral body
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US6723335B1 (en) * 2000-04-07 2004-04-20 Jeffrey William Moehlenbruck Methods and compositions for treating intervertebral disc degeneration
US20080086133A1 (en) * 2003-05-16 2008-04-10 Spineology Expandable porous mesh bag device and methods of use for reduction, filling, fixation and supporting of bone
DE60141653D1 (en) * 2000-07-21 2010-05-06 Spineology Group Llc A STRONG, POROUS NET BAG DEVICE AND ITS USE IN BONE SURGERY
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
DE60140004D1 (en) 2000-08-08 2009-11-05 Warsaw Orthopedic Inc DEVICE FOR STEREOTAKTIC IMPLANTATION
US7601174B2 (en) * 2000-08-08 2009-10-13 Warsaw Orthopedic, Inc. Wear-resistant endoprosthetic devices
WO2002011650A2 (en) * 2000-08-08 2002-02-14 Sdgi Holdings, Inc. Implantable joint prosthesis
US7226480B2 (en) * 2000-08-15 2007-06-05 Depuy Spine, Inc. Disc prosthesis
US6458159B1 (en) * 2000-08-15 2002-10-01 John S. Thalgott Disc prosthesis
JP2004521666A (en) * 2000-08-28 2004-07-22 アドバンスト バイオ サーフェイシズ,インコーポレイティド Methods and systems for enhancing mammalian joints
US20020026244A1 (en) * 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US7503936B2 (en) * 2000-08-30 2009-03-17 Warsaw Orthopedic, Inc. Methods for forming and retaining intervertebral disc implants
AU2001285351B2 (en) 2000-08-30 2004-12-02 Warsaw Orthopedic, Inc. Intervertebral disc nucleus implants and methods
US7204851B2 (en) * 2000-08-30 2007-04-17 Sdgi Holdings, Inc. Method and apparatus for delivering an intervertebral disc implant
US20050154463A1 (en) * 2000-08-30 2005-07-14 Trieu Hal H. Spinal nucleus replacement implants and methods
EP1832300A3 (en) * 2000-09-18 2008-02-27 Organogenesis Inc. Method for treating a patient using a cultured connective tissue construct
MXPA03002415A (en) * 2000-09-18 2004-07-08 Organogenesis Inc Method for treating a patient using a cultured connective tissue construct.
US6733531B1 (en) * 2000-10-20 2004-05-11 Sdgi Holdings, Inc. Anchoring devices and implants for intervertebral disc augmentation
ES2238500T3 (en) * 2000-10-27 2005-09-01 Sdgi Holdings, Inc. RING REPAIR SYSTEM.
US6562045B2 (en) 2001-02-13 2003-05-13 Sdgi Holdings, Inc. Machining apparatus
US6632235B2 (en) * 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
US6770075B2 (en) 2001-05-17 2004-08-03 Robert S. Howland Spinal fixation apparatus with enhanced axial support and methods for use
US7314467B2 (en) * 2002-04-24 2008-01-01 Medical Device Advisory Development Group, Llc. Multi selective axis spinal fixation system
US20060064092A1 (en) * 2001-05-17 2006-03-23 Howland Robert S Selective axis serrated rod low profile spinal fixation system
US20040243128A1 (en) * 2001-05-17 2004-12-02 Howland Robert S. Selective axis posterior lumbar spinal plating fixation apparatus and methods for use
US7156877B2 (en) * 2001-06-29 2007-01-02 The Regents Of The University Of California Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs
US20090234457A1 (en) * 2001-06-29 2009-09-17 The Regents Of The University Of California Systems, devices and methods for treatment of intervertebral disorders
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
US7361195B2 (en) 2001-07-16 2008-04-22 Depuy Products, Inc. Cartilage repair apparatus and method
WO2003007784A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Meniscus regeneration device and method
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
WO2003007790A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
WO2003007839A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Devices form naturally occurring biologically derived
JP4197157B2 (en) * 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド Cartilage repair and reproduction apparatus and method
US7163563B2 (en) * 2001-07-16 2007-01-16 Depuy Products, Inc. Unitary surgical device and method
AU2004268628B2 (en) * 2001-08-31 2009-11-12 Spinal Simplicity, Llc Crosslinking reagents for treating intervertebral disc disorders
US8119599B2 (en) 2001-08-31 2012-02-21 Orthopeutics, L.P. Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
US7025787B2 (en) * 2001-11-26 2006-04-11 Sdgi Holdings, Inc. Implantable joint prosthesis and associated instrumentation
MXPA04005707A (en) * 2001-12-10 2005-06-20 Colbar Lifescience Ltd D Methods, devices, and preparations for intervertebral disc treatment.
US7232802B2 (en) 2001-12-21 2007-06-19 Zimmer Orthobiologics, Inc. Compositions and methods for promoting myocardial and peripheral angiogenesis
US6736850B2 (en) * 2001-12-28 2004-05-18 Spinal Concepts, Inc. Vertebral pseudo arthrosis device and method
US20060129242A1 (en) * 2001-12-28 2006-06-15 Brian Bergeron Pseudo arthrosis device
US6761723B2 (en) * 2002-01-14 2004-07-13 Dynamic Spine, Inc. Apparatus and method for performing spinal surgery
US20030220692A1 (en) * 2002-02-09 2003-11-27 Shapiro Irving M. Preparations of nucleus pulposus cells and methods for their generation, identification, and use
AR038680A1 (en) 2002-02-19 2005-01-26 Synthes Ag INTERVERTEBRAL IMPLANT
US8388684B2 (en) 2002-05-23 2013-03-05 Pioneer Signal Technology, Inc. Artificial disc device
US7001433B2 (en) * 2002-05-23 2006-02-21 Pioneer Laboratories, Inc. Artificial intervertebral disc device
US20040049283A1 (en) * 2002-06-04 2004-03-11 Tushar Patel Medical implant and method of reducing back pain
US7594934B2 (en) * 2002-06-14 2009-09-29 Crosscart, Inc. Galactosidase-treated prosthetic devices
US7622562B2 (en) * 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US6958078B2 (en) * 2002-08-19 2005-10-25 The University Of Toledo Bioartificial intervertebral disc
US7744651B2 (en) * 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
US20040054414A1 (en) * 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
US7887593B2 (en) * 2002-09-18 2011-02-15 Warsaw Orthopedic, Inc. Method of implanting natural tissue within the vertebral disc nucleus space using a drawstring
US7309359B2 (en) * 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US6966929B2 (en) * 2002-10-29 2005-11-22 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with a spacer
US7273496B2 (en) * 2002-10-29 2007-09-25 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with crossbar spacer and method
US7083649B2 (en) * 2002-10-29 2006-08-01 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with translating pivot point
US7497859B2 (en) * 2002-10-29 2009-03-03 Kyphon Sarl Tools for implanting an artificial vertebral disk
US20040133278A1 (en) * 2002-10-31 2004-07-08 Marino James F. Spinal disc implant
CA2735334A1 (en) * 2002-11-05 2004-05-21 Spineology, Inc. A semi-biological intervertebral disc replacement system
JP2006515765A (en) * 2002-11-15 2006-06-08 エスディージーアイ・ホールディングス・インコーポレーテッド Collagen-based materials and methods for treating synovial joints
US20040186471A1 (en) * 2002-12-07 2004-09-23 Sdgi Holdings, Inc. Method and apparatus for intervertebral disc expansion
US20040210310A1 (en) * 2002-12-10 2004-10-21 Trieu Hai H. Implant system and method for intervertebral disc augmentation
US6974479B2 (en) * 2002-12-10 2005-12-13 Sdgi Holdings, Inc. System and method for blocking and/or retaining a prosthetic spinal implant
CA2513055A1 (en) * 2003-01-31 2004-08-19 Zimmer Orthobiologics, Inc. Hydrogel compositions comprising nucleus pulposus tissue
BRPI0317820B1 (en) 2003-02-06 2015-06-30 Synthes Gmbh Intervertebral Implant
US7364589B2 (en) * 2003-02-12 2008-04-29 Warsaw Orthopedic, Inc. Mobile bearing articulating disc
US7803395B2 (en) 2003-05-15 2010-09-28 Biomerix Corporation Reticulated elastomeric matrices, their manufacture and use in implantable devices
KR100828144B1 (en) * 2003-06-20 2008-05-14 인트린식 쎄라퓨틱스 인코포레이티드 Implant for intervertebral disc annular defect
US20040260300A1 (en) * 2003-06-20 2004-12-23 Bogomir Gorensek Method of delivering an implant through an annular defect in an intervertebral disc
US7819880B2 (en) * 2003-06-30 2010-10-26 Depuy Products, Inc. Implant delivery instrument
US7559941B2 (en) * 2003-06-30 2009-07-14 Depuy Products, Inc. Instrument for delivery of implant
US7563266B2 (en) * 2003-06-30 2009-07-21 Depuy Products, Inc. Slide and kit for delivering implants
US7473259B2 (en) 2003-06-30 2009-01-06 Depuy Products, Inc. Implant stabilizing instrument, kit and method
US7909869B2 (en) 2003-08-05 2011-03-22 Flexuspine, Inc. Artificial spinal unit assemblies
US8052723B2 (en) * 2003-08-05 2011-11-08 Flexuspine Inc. Dynamic posterior stabilization systems and methods of use
US7753958B2 (en) 2003-08-05 2010-07-13 Gordon Charles R Expandable intervertebral implant
WO2005013852A2 (en) * 2003-08-07 2005-02-17 Dynamic Spine, Inc. Intervertebral prosthetic device and associated devices and methods for implanting the intervertebral prosthetic device
DE60318061T2 (en) * 2003-10-17 2008-09-18 Coligne Ag fusion implant
EP1682161A4 (en) * 2003-10-29 2011-12-07 Gentis Inc Polymerizable emulsions for tissue engineering
US7520899B2 (en) * 2003-11-05 2009-04-21 Kyphon Sarl Laterally insertable artificial vertebral disk replacement implant with crossbar spacer
US20050149192A1 (en) * 2003-11-20 2005-07-07 St. Francis Medical Technologies, Inc. Intervertebral body fusion cage with keels and implantation method
US7837732B2 (en) * 2003-11-20 2010-11-23 Warsaw Orthopedic, Inc. Intervertebral body fusion cage with keels and implantation methods
US7691146B2 (en) * 2003-11-21 2010-04-06 Kyphon Sarl Method of laterally inserting an artificial vertebral disk replacement implant with curved spacer
US20050283237A1 (en) * 2003-11-24 2005-12-22 St. Francis Medical Technologies, Inc. Artificial spinal disk replacement device with staggered vertebral body attachments
US20050154462A1 (en) * 2003-12-02 2005-07-14 St. Francis Medical Technologies, Inc. Laterally insertable artificial vertebral disk replacement implant with translating pivot point
US7481839B2 (en) * 2003-12-02 2009-01-27 Kyphon Sarl Bioresorbable interspinous process implant for use with intervertebral disk remediation or replacement implants and procedures
US7217291B2 (en) 2003-12-08 2007-05-15 St. Francis Medical Technologies, Inc. System and method for replacing degenerated spinal disks
US20050143826A1 (en) * 2003-12-11 2005-06-30 St. Francis Medical Technologies, Inc. Disk repair structures with anchors
US7763077B2 (en) * 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
US20050187631A1 (en) * 2004-01-27 2005-08-25 Sdgi Holdings, Inc. Prosthetic device
US20050165487A1 (en) * 2004-01-28 2005-07-28 Muhanna Nabil L. Artificial intervertebral disc
US7485145B2 (en) * 2004-02-23 2009-02-03 Alphatec Spine, Incorporated Artificial intervertebral disc assembly
NZ549953A (en) 2004-03-17 2010-11-26 Revivicor Inc Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase
WO2005092248A1 (en) * 2004-03-26 2005-10-06 Nuvasive Inc. Porous implant for spinal disc nucleus replacement
ATE506919T1 (en) * 2004-03-26 2011-05-15 Nuvasive Inc DISC PROSTHESIS
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US20080269900A1 (en) * 2004-05-20 2008-10-30 Christopher Reah Surgical Implants
US20050273172A1 (en) * 2004-06-07 2005-12-08 Patil Arun A Artificial disc and uses therefor
DE102004041354A1 (en) 2004-08-25 2006-03-30 Buck, Alfred Implant for surgical use in humans or vertebrates
US7799081B2 (en) 2004-09-14 2010-09-21 Aeolin, Llc System and method for spinal fusion
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US7303074B2 (en) * 2004-09-22 2007-12-04 Dombrowski Trudy M Foldable organizer device
US7575600B2 (en) * 2004-09-29 2009-08-18 Kyphon Sarl Artificial vertebral disk replacement implant with translating articulation contact surface and method
US7481840B2 (en) * 2004-09-29 2009-01-27 Kyphon Sarl Multi-piece artificial spinal disk replacement device with selectably positioning articulating element
US20060069438A1 (en) * 2004-09-29 2006-03-30 Zucherman James F Multi-piece artificial spinal disk replacement device with multi-segmented support plates
US20060089719A1 (en) * 2004-10-21 2006-04-27 Trieu Hai H In situ formation of intervertebral disc implants
WO2006050087A2 (en) 2004-10-29 2006-05-11 Depuy Products, Inc. Coordinate instrument set
US7513866B2 (en) * 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
EP1652484B1 (en) 2004-10-29 2007-08-01 DePuy Products, Inc. Instruments and kit for suture management
AU2005227409B2 (en) * 2004-10-29 2012-01-19 Depuy Products, Inc. Implant system with sizing templates
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US20060200245A1 (en) * 2005-03-07 2006-09-07 Sdgi Holdings, Inc. Materials, devices, and methods for in-situ formation of composite intervertebral implants
CA2604622A1 (en) * 2005-04-15 2006-10-26 Musculoskeletal Transplant Foundation Vertebral disc repair
GB0514891D0 (en) * 2005-07-20 2005-08-24 Pearsalls Ltd Improvements in and relating to implants
US20090105826A1 (en) * 2005-06-03 2009-04-23 Mcleod Alan Surgical Implants
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
GB0516846D0 (en) 2005-08-17 2005-09-21 Knight David P Meniscal repair device
US20070112360A1 (en) * 2005-11-15 2007-05-17 Patrick De Deyne Bioprosthetic device
US20070179618A1 (en) * 2006-01-31 2007-08-02 Sdgi Holdings, Inc. Intervertebral prosthetic disc
EP1988855A2 (en) 2006-02-27 2008-11-12 Synthes GmbH Intervertebral implant with fixation geometry
US8118869B2 (en) 2006-03-08 2012-02-21 Flexuspine, Inc. Dynamic interbody device
EP2019653B1 (en) * 2006-04-28 2016-11-16 The University of Hong Kong Bioengineered intervertebral discs and methods for their preparation
US8821549B2 (en) 2006-06-13 2014-09-02 Anova Corporation Methods and apparatus for anulus repair
US8764835B2 (en) 2006-06-13 2014-07-01 Bret A. Ferree Intervertebral disc treatment methods and apparatus
US9232938B2 (en) 2006-06-13 2016-01-12 Anova Corp. Method and apparatus for closing fissures in the annulus fibrosus
US8834496B2 (en) 2006-06-13 2014-09-16 Bret A. Ferree Soft tissue repair methods and apparatus
US20080004431A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic Inc Method of manufacturing an injectable collagen material
US8399619B2 (en) * 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US20080004703A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic, Inc. Method of treating a patient using a collagen material
US8118779B2 (en) * 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US7959683B2 (en) * 2006-07-25 2011-06-14 Musculoskeletal Transplant Foundation Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation
US8048618B2 (en) * 2006-07-26 2011-11-01 The University Of Hong Kong Method for preparing and preserving a natural allograft intervertebral disk for humans
US20080026032A1 (en) * 2006-07-27 2008-01-31 Zubery Yuval Composite implants for promoting bone regeneration and augmentation and methods for their preparation and use
US20080113008A1 (en) * 2006-09-14 2008-05-15 Karen Roche Absorbent fabric implant
WO2008034135A2 (en) 2006-09-15 2008-03-20 Pioneer Surgical Technology, Inc. Joint arthroplasty devices having articulating members
US8715350B2 (en) 2006-09-15 2014-05-06 Pioneer Surgical Technology, Inc. Systems and methods for securing an implant in intervertebral space
US8066750B2 (en) 2006-10-06 2011-11-29 Warsaw Orthopedic, Inc Port structures for non-rigid bone plates
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US7905922B2 (en) 2006-12-20 2011-03-15 Zimmer Spine, Inc. Surgical implant suitable for replacement of an intervertebral disc
US7959677B2 (en) * 2007-01-19 2011-06-14 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US7942104B2 (en) * 2007-01-22 2011-05-17 Nuvasive, Inc. 3-dimensional embroidery structures via tension shaping
US7946236B2 (en) * 2007-01-31 2011-05-24 Nuvasive, Inc. Using zigzags to create three-dimensional embroidered structures
WO2008098125A2 (en) * 2007-02-08 2008-08-14 Nuvasive, Inc. Medical implants with pre-settled cores and related methods
US10278947B2 (en) 2007-02-28 2019-05-07 Orthopeutics, L.P. Crosslinker enhanced repair of connective tissues
WO2009009020A1 (en) 2007-07-12 2009-01-15 Discgenics Human disc tissue
US8282681B2 (en) * 2007-08-13 2012-10-09 Nuvasive, Inc. Bioresorbable spinal implant and related methods
US8187330B2 (en) 2007-10-22 2012-05-29 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8157844B2 (en) * 2007-10-22 2012-04-17 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8162994B2 (en) * 2007-10-22 2012-04-24 Flexuspine, Inc. Posterior stabilization system with isolated, dual dampener systems
US8182514B2 (en) * 2007-10-22 2012-05-22 Flexuspine, Inc. Dampener system for a posterior stabilization system with a fixed length elongated member
US8523912B2 (en) * 2007-10-22 2013-09-03 Flexuspine, Inc. Posterior stabilization systems with shared, dual dampener systems
US8267965B2 (en) * 2007-10-22 2012-09-18 Flexuspine, Inc. Spinal stabilization systems with dynamic interbody devices
US8556949B2 (en) 2007-11-14 2013-10-15 DePuy Synthes Products, LLC Hybrid bone fixation element and methods of using the same
CA2705684A1 (en) 2007-11-16 2009-05-22 Synthes Usa, Llc Low profile intervertebral implant
AU2009228035A1 (en) * 2008-03-28 2009-10-01 Spineology Inc. Method and device for interspinous process fusion
US8377135B1 (en) 2008-03-31 2013-02-19 Nuvasive, Inc. Textile-based surgical implant and related methods
US20090276051A1 (en) 2008-05-05 2009-11-05 Spinalmotion, Inc. Polyaryletherketone Artificial Intervertebral Disc
DE102008042401A1 (en) 2008-09-26 2010-04-08 Forschungszentrum Karlsruhe Gmbh Intervertebral disk implant for use between vertebras of spinal column of humans and vertebrate animals, has support component comprising flexible core and biocompatible matrix layer, which is formed with tissue cells
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US20100145460A1 (en) 2008-11-07 2010-06-10 Mcdonough William P Zero-profile interbody spacer and coupled plate assembly
US7805920B2 (en) * 2008-11-13 2010-10-05 The Toro Company Lawn mower having steeply inclined exit tunnel and battery access through rear face of mower cutting deck
US8216316B2 (en) 2008-12-17 2012-07-10 X-Spine Systems, Inc. Prosthetic implant with biplanar angulation and compound angles
US8157865B2 (en) * 2009-01-22 2012-04-17 Stephen Hochschuler Apparatus and method for stabilizing adjacent bone portions
WO2010129692A1 (en) 2009-05-05 2010-11-11 Cornell University Composite tissue-engineered intervertebral disc with self-assembled annular alignment
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
US8353964B2 (en) 2010-11-04 2013-01-15 Carpenter Clyde T Anatomic total disc replacement
WO2012088238A2 (en) 2010-12-21 2012-06-28 Synthes Usa, Llc Intervertebral implants, systems, and methods of use
US9241809B2 (en) 2010-12-21 2016-01-26 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US8388687B2 (en) 2011-03-25 2013-03-05 Flexuspine, Inc. Interbody device insertion systems and methods
KR101273204B1 (en) * 2011-08-22 2013-06-11 주식회사 셀루메드 Methof for producing a composition for inducing of bone formation
US9526627B2 (en) 2011-11-17 2016-12-27 Exactech, Inc. Expandable interbody device system and method
EP2793964B1 (en) * 2011-12-20 2019-03-20 LifeCell Corporation Sheet tissue products
BR112014014975B1 (en) 2011-12-20 2019-06-25 Lifecell Corporation A method of producing a fabric composition
US9241807B2 (en) 2011-12-23 2016-01-26 Pioneer Surgical Technology, Inc. Systems and methods for inserting a spinal device
US9271821B2 (en) 2012-01-24 2016-03-01 Lifecell Corporation Elongated tissue matrices
US9155578B2 (en) 2012-02-28 2015-10-13 DePuy Synthes Products, Inc. Expandable fastener
US10179012B2 (en) 2013-01-28 2019-01-15 Cartiva, Inc. Systems and methods for orthopedic repair
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
US9492288B2 (en) 2013-02-20 2016-11-15 Flexuspine, Inc. Expandable fusion device for positioning between adjacent vertebral bodies
US10327910B2 (en) 2013-03-14 2019-06-25 X-Spine Systems, Inc. Spinal implant and assembly
AT14375U1 (en) 2014-02-12 2015-10-15 Ho Med Handelsgesellschaft M B H Implant for insertion between vertebral bodies of the spine
US9517144B2 (en) 2014-04-24 2016-12-13 Exactech, Inc. Limited profile intervertebral implant with incorporated fastening mechanism
US10398565B2 (en) 2014-04-24 2019-09-03 Choice Spine, Llc Limited profile intervertebral implant with incorporated fastening and locking mechanism
US9867718B2 (en) 2014-10-22 2018-01-16 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US11298931B2 (en) 2015-11-24 2022-04-12 Agada Medical Ltd. Intervertebral disc replacement
US10390959B2 (en) 2015-11-24 2019-08-27 Agada Medical Ltd. Intervertebral disc replacement
CA3074834A1 (en) 2017-09-08 2019-03-14 Pioneer Surgical Technology, Inc. Intervertebral implants, instruments, and methods
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551560A (en) * 1967-10-02 1970-12-29 Heinrich F Thiele Process of reconstructing tendons,cartilage,nerve sheaths,and products
CA962806A (en) * 1970-06-04 1975-02-18 Ontario Research Foundation Surgical prosthetic device
CA992255A (en) * 1971-01-25 1976-07-06 Cutter Laboratories Prosthesis for spinal repair
US3875595A (en) * 1974-04-15 1975-04-08 Edward C Froning Intervertebral disc prosthesis and instruments for locating same
US4085466A (en) * 1974-11-18 1978-04-25 National Research Development Corporation Prosthetic joint device
US4060081A (en) * 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
GB1515963A (en) * 1975-07-15 1978-06-28 Massachusetts Inst Technology Crosslinked collagen-mucopolysaccharide composite materials
US4280954A (en) * 1975-07-15 1981-07-28 Massachusetts Institute Of Technology Crosslinked collagen-mucopolysaccharide composite materials
CA1146301A (en) * 1980-06-13 1983-05-17 J. David Kuntz Intervertebral disc prosthesis
US4378224A (en) * 1980-09-19 1983-03-29 Nimni Marcel E Coating for bioprosthetic device and method of making same
US4344193A (en) * 1980-11-28 1982-08-17 Kenny Charles H Meniscus prosthesis
US4400833A (en) * 1981-06-10 1983-08-30 Kurland Kenneth Z Means and method of implanting bioprosthetics
US4350629A (en) * 1981-07-29 1982-09-21 Massachusetts Institute Of Technology Procedures for preparing composite materials from collagen and glycosaminoglycan
US4505266A (en) * 1981-10-26 1985-03-19 Massachusetts Institute Of Technology Method of using a fibrous lattice
US4418691A (en) * 1981-10-26 1983-12-06 Massachusetts Institute Of Technology Method of promoting the regeneration of tissue at a wound
US4458678A (en) * 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US4787900A (en) * 1982-04-19 1988-11-29 Massachusetts Institute Of Technology Process for forming multilayer bioreplaceable blood vessel prosthesis
US4544516A (en) * 1982-07-28 1985-10-01 Battelle Development Corporation Collagen orientation
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4589881A (en) * 1982-08-04 1986-05-20 La Jolla Cancer Research Foundation Polypeptide
US4661111A (en) * 1982-08-04 1987-04-28 La Jolla Cancer Research Foundation Polypeptide
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
US4448718A (en) * 1983-09-13 1984-05-15 Massachusetts Institute Of Technology Method for the preparation of collagen-glycosaminoglycan composite materials
GB2148901A (en) * 1983-10-04 1985-06-05 Johnson & Johnson Protein/polysaccharide complexes
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4627853A (en) * 1985-05-29 1986-12-09 American Hospital Supply Corporation Method of producing prostheses for replacement of articular cartilage and prostheses so produced
NL8700113A (en) * 1987-01-19 1988-08-16 Groningen Science Park INK, SUITABLE FOR TREATMENT BY RECONSTRUCTIVE SURGERY, WITH TISSUE-SPECIFIC POROSITY, AND METHOD FOR MANUFACTURING THE ENTAGMENT.
US4880429A (en) * 1987-07-20 1989-11-14 Stone Kevin R Prosthetic meniscus
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
US4911718A (en) * 1988-06-10 1990-03-27 University Of Medicine & Dentistry Of N.J. Functional and biocompatible intervertebral disc spacer

Also Published As

Publication number Publication date
EP0527936A1 (en) 1993-02-24
EP0527936A4 (en) 1993-07-28
AU647144B2 (en) 1994-03-17
US5108438A (en) 1992-04-28
DE69126971D1 (en) 1997-09-04
DE69126971T2 (en) 1998-02-12
CA2082427C (en) 2000-10-31
ATE155668T1 (en) 1997-08-15
JP3162375B2 (en) 2001-04-25
EP0527936B1 (en) 1997-07-23
JPH05508333A (en) 1993-11-25
WO1991016867A1 (en) 1991-11-14
AU7959191A (en) 1991-11-27

Similar Documents

Publication Publication Date Title
CA2082427A1 (en) Prosthetic intervertebral disc
CA2050471A1 (en) Prosthetic meniscus
MX9603249A (en) Bioremodelable collagen graft prosthesis.
WO1994007432A3 (en) Porous vascular implants
DE3378303D1 (en) Polymeric acrylic prosthesis
EP1083828A4 (en) Bioengineered vascular graft prostheses
DE3866614D1 (en) INTERMEDIATE SPINE PROSTHESIS.
CA2183263A1 (en) Improved process for fixation of calcification-resistant biological tissue
WO1996036368A3 (en) Composite materials using bone bioactive glass and ceramic fibers
CA2207751A1 (en) Controlled porosity endovascular implant
CA2188563A1 (en) Stent with collagen
DK0871419T3 (en) Intervertebral implant designed as intersomatic cage
WO1999062424A3 (en) Bioengineered tubular graft prostheses
IL98255A0 (en) Biocompatible perforated membranes,processes for their use as a support in the in vitro growth of epithelial cells,the artificial skin obtained in this manner,and its use in skin grafts
GR3034453T3 (en) Intraocular prosthesis.
GB9400163D0 (en) Membrane
AU2424588A (en) Prosthetic meniscus
GB1505215A (en) Composite prosthetic device with porous polymeric coating
EP0965310A4 (en) Artificial blood vessel
CA2014542A1 (en) Medical implant and method for the manufacture thereof
CA2319019A1 (en) Biocompatible structure comprising means for enhanced fibrovascular ingrowth
FR2746652B1 (en) USE OF EGG SHELL AS BONE IMPLANT AND METHOD OF MANUFACTURE
Cooke et al. Biomechanical Matching of Tendon and Ligament Prostheses
MX9707655A (en) Peracetic acid crosslinked non-antigenic icl grafts.

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry