CA2143136A1 - Rub on topical anesthetic - Google Patents
Rub on topical anestheticInfo
- Publication number
- CA2143136A1 CA2143136A1 CA002143136A CA2143136A CA2143136A1 CA 2143136 A1 CA2143136 A1 CA 2143136A1 CA 002143136 A CA002143136 A CA 002143136A CA 2143136 A CA2143136 A CA 2143136A CA 2143136 A1 CA2143136 A1 CA 2143136A1
- Authority
- CA
- Canada
- Prior art keywords
- skin
- anesthetic
- medium
- abrasive
- topical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
Abstract
The invention is a topical anesthetic that is meant to be rubbed on the skin where the topical anesthetic medium contains ingredients that in combination with rubbing breaks down or reduces the barriers which slow the penetration of the anesthetic molecule. These ingredients include a skin abrasive such as pumice and/or non-toxic solvents.
Description
, ~ 21~31'361' Rub On Topical Anesthetic The invention relates to topical ~nP~fhPfir~ In dentistry and medicine topical anesthetics are placed on the skin so that the anesthetic molecule will soak into and through the skin to numb superficial nenes. The anesthetic is dissolved in a solvent and applied on the skin surface in a fluid, gel or cream medium.
I am a dentist and it has become apparent to me that the anesthetic is taking much too long to soak into and through the skin to ~ lh~ the superficial nerves.
In order to speed the absorption, I have tried to rub or massage the anesthetic into the skin. However, even this technique does not allow penetration into the skin to be fast enough or profound enough. After closer analysis, it can be seen that it is quite difficult for the anesthetic to penetrate into the skin due to a number of barriers to the anesthetic.
These barriers include saliva, the mucous in the saliva, skin oils and the skin cells themselves.
In order to provide the patient with optrmum comfort more quickly and more profoundly, a new type of topical should be provided to the ~.vrt";v~ tbat is not meant to sit on the skin as is currently the case, but that is meant to be massaged on the skin. This new topical anesthetic medium should have added ingredients that, when massaged, will effectively eliminate or weaken the barriers to anesthetic pPnPtr~tinn These barriers can be overcome or reduced by adding the followmg to a topical medium which is rubbed on the skin.
~ 2 2~3136 The integrity of a layer of saliva and mucous in the saliva could be brok~n up by massaging the skin with a topical anesthetic medium that contains a non-toxic salivary mucous solvent. A layer of skin oils could also be broken up by massaging a topical anesthetic medium that contarns a non-toxic solvent for skin oils. The skin cells can be loosened and some surface cells removed by massaging or rubbing the skin with an abrasive.
An abrasive can be contained in the topical ointment, gel or cream such as pumice, and then the topical medium rubbed on the skin. Or the abrasive can be in the form of an abrasive applicator which has an abrasive surface. Topical anesthetic can be applied to the abrasive applicator. This abrasive applicator can then be used to massage the topical into the skin while loosening and removing surface skin cells.
A topical anesthetic can also be made more efficient by increasmg the ~ ;ll" of anesthetic in the topical medium.
I am a dentist and it has become apparent to me that the anesthetic is taking much too long to soak into and through the skin to ~ lh~ the superficial nerves.
In order to speed the absorption, I have tried to rub or massage the anesthetic into the skin. However, even this technique does not allow penetration into the skin to be fast enough or profound enough. After closer analysis, it can be seen that it is quite difficult for the anesthetic to penetrate into the skin due to a number of barriers to the anesthetic.
These barriers include saliva, the mucous in the saliva, skin oils and the skin cells themselves.
In order to provide the patient with optrmum comfort more quickly and more profoundly, a new type of topical should be provided to the ~.vrt";v~ tbat is not meant to sit on the skin as is currently the case, but that is meant to be massaged on the skin. This new topical anesthetic medium should have added ingredients that, when massaged, will effectively eliminate or weaken the barriers to anesthetic pPnPtr~tinn These barriers can be overcome or reduced by adding the followmg to a topical medium which is rubbed on the skin.
~ 2 2~3136 The integrity of a layer of saliva and mucous in the saliva could be brok~n up by massaging the skin with a topical anesthetic medium that contains a non-toxic salivary mucous solvent. A layer of skin oils could also be broken up by massaging a topical anesthetic medium that contarns a non-toxic solvent for skin oils. The skin cells can be loosened and some surface cells removed by massaging or rubbing the skin with an abrasive.
An abrasive can be contained in the topical ointment, gel or cream such as pumice, and then the topical medium rubbed on the skin. Or the abrasive can be in the form of an abrasive applicator which has an abrasive surface. Topical anesthetic can be applied to the abrasive applicator. This abrasive applicator can then be used to massage the topical into the skin while loosening and removing surface skin cells.
A topical anesthetic can also be made more efficient by increasmg the ~ ;ll" of anesthetic in the topical medium.
Claims
#1 An ointment, cream, gel or other medium which contains an anesthetic chemical which is placed topically, or on top of the skin, where: the medium also contains an abrasive so that if the said medium is rubbed on the skin the abrasive will loosen surface skin cells.
#2 A fluid, ointment, cream, gel or other medium which contains an anesthetic chemical which is placed topically, or in other words on top of the skin, where: the medium also contains a non-toxic solvent which is able to dissolve mucous or is able to dissolve skin oils or is able to dissolve both so that either or both the mucous and/or the skin oils will not be able to create a barrier to the migration of the anesthetic to the skin and through the skin.
#3 A fluid, ointment, cream, gel or other medium which contains an anesthetic chemical which is placed topically, or in other words on top of the skin, where: the medium also contains 2 or more non-toxic solvents that individually or in combination are able to dissolve either any or all of the following, mucous, saliva, and/or skin oils so that the mucous and/or the saliva and/or the skin oils will not be able to create a barrier to the migration of the anesthetic to the skin and through the skin.
#4 An applicator with an abrasive surface where a topical anesthetic medium is applied to the said abrasive surface and then the said abrasive surface rubbed on the skin so that the anesthetic is rubbed into the skin while the abrasive surface is loosening and removing some skin cells.
#5 An ointment, cream, gel or other medium which contains an anesthetic chemical as in
Claim 1 where the abrasive is pumice or silica or any non-toxic tissue compatible abrasive.
#6 A fluid, ointment, cream, gel or other medium which contains an anesthetic as in Claims 2 and 3 where the non-toxic solvent is any tissue compatible organic or inorganic solvent.
#7 A rubbing topical anesthetic where the anesthetic chemical is mixed to be higher in its concentration within the Rub on topical than is normally found in currently used topical anesthetics.
#6 A fluid, ointment, cream, gel or other medium which contains an anesthetic as in Claims 2 and 3 where the non-toxic solvent is any tissue compatible organic or inorganic solvent.
#7 A rubbing topical anesthetic where the anesthetic chemical is mixed to be higher in its concentration within the Rub on topical than is normally found in currently used topical anesthetics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002143136A CA2143136A1 (en) | 1995-02-22 | 1995-02-22 | Rub on topical anesthetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002143136A CA2143136A1 (en) | 1995-02-22 | 1995-02-22 | Rub on topical anesthetic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2143136A1 true CA2143136A1 (en) | 1996-08-23 |
Family
ID=4155286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002143136A Abandoned CA2143136A1 (en) | 1995-02-22 | 1995-02-22 | Rub on topical anesthetic |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2143136A1 (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187294B1 (en) * | 1999-06-10 | 2001-02-13 | Russell Anthony Penner | Topical anesthetic prophylaxis composition and the method for use thereof in scaling and polishing teeth |
| US6211243B1 (en) | 1999-09-22 | 2001-04-03 | B. Ron Johnson | Methods for treating cold sores with anti-infective compositions |
| US6759434B2 (en) | 1999-09-22 | 2004-07-06 | B. Ron Johnson | Anti-infective compositions, methods and systems for treating disordered tissue |
| US8173709B2 (en) | 1999-09-22 | 2012-05-08 | Quadex Pharmaceuticals, Llc | Anti-infective methods for treating pathogen-induced disordered tissues |
| US9125911B2 (en) | 2013-03-14 | 2015-09-08 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered tissues |
| US9463180B2 (en) | 2013-03-14 | 2016-10-11 | Quadex Pharmaceuticals, Llc | Treatment of molluscum contagiosum |
| US9549930B2 (en) | 2013-03-14 | 2017-01-24 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered and/or prodromal stage tissue |
-
1995
- 1995-02-22 CA CA002143136A patent/CA2143136A1/en not_active Abandoned
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187294B1 (en) * | 1999-06-10 | 2001-02-13 | Russell Anthony Penner | Topical anesthetic prophylaxis composition and the method for use thereof in scaling and polishing teeth |
| US6211243B1 (en) | 1999-09-22 | 2001-04-03 | B. Ron Johnson | Methods for treating cold sores with anti-infective compositions |
| US6410599B1 (en) | 1999-09-22 | 2002-06-25 | Ron Johnson | Antiseptic compositions suitable for application to human tissue |
| US6414032B1 (en) | 1999-09-22 | 2002-07-02 | B. Ron Johnson | Anti-infective compositions for treating disordered tissue such as cold sores |
| US6420431B1 (en) | 1999-09-22 | 2002-07-16 | B. Ron Johnson | Methods for treating disordered tissue through agitated delivery of anti-infective compositions |
| US6423750B1 (en) | 1999-09-22 | 2002-07-23 | B. Ron Johnson | Systems for delivering anti-infective compositions to treat disordered tissue such as cold sores |
| US6759434B2 (en) | 1999-09-22 | 2004-07-06 | B. Ron Johnson | Anti-infective compositions, methods and systems for treating disordered tissue |
| US8173709B2 (en) | 1999-09-22 | 2012-05-08 | Quadex Pharmaceuticals, Llc | Anti-infective methods for treating pathogen-induced disordered tissues |
| US9125911B2 (en) | 2013-03-14 | 2015-09-08 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered tissues |
| US9463180B2 (en) | 2013-03-14 | 2016-10-11 | Quadex Pharmaceuticals, Llc | Treatment of molluscum contagiosum |
| US9545408B2 (en) | 2013-03-14 | 2017-01-17 | Quadex Pharmaceuticals, Inc. | Combined systemic and topical treatment of disordered tissues |
| US9549930B2 (en) | 2013-03-14 | 2017-01-24 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered and/or prodromal stage tissue |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6414032B1 (en) | Anti-infective compositions for treating disordered tissue such as cold sores | |
| DK159789D0 (en) | MEDICATED SKIN CARE PREPARATION, ITS MANUFACTURING AND USE | |
| BR0309890A (en) | Pharmaceutical composition containing blood plasma or blood serum used in the treatment of lesions, as well as its method and application process | |
| USRE37274E1 (en) | Method for nutritional oxygenation of the skin | |
| BR9914954A (en) | Implant with cavities containing therapeutic agents | |
| RU2389474C2 (en) | Nanostructured thixotropic inorganic peeling gels | |
| CN1181809C (en) | Compositions for oral cavity | |
| BR9909277A (en) | Compounds with activity at muscarinic receptors | |
| ATE177640T1 (en) | PHARMACEUTICAL COMPOSITION FOR WOUND, SCARS AND KELOID TREATMENT | |
| BR0014512A (en) | Topical treatment for streptococcal infections | |
| CN1175206A (en) | Formulations and methods for reducing skin irritation | |
| ES2166783T3 (en) | ACTIVATED FACTOR VIII USED AS A THERAPEUTIC AGENT AND METHOD FOR THE TREATMENT OF FACTOR DEFICIENCY VIII. | |
| US3574859A (en) | Process for the treatment of hypertrophied gums | |
| CA2143136A1 (en) | Rub on topical anesthetic | |
| BR0209897A (en) | Wet skin treatment composition, moistening and skin protection process, manufacturing process, moisture sensation retention method and skin dryness reduction method | |
| IT1177863B (en) | A GANGLIOSIDIC MIXTURE AS A THERAPEUTIC AGENT TO ELIMINATE PAIN IN PERIPHERAL NEUROPATHIES | |
| EP1074245A3 (en) | Composition using mineral salts for therapeutic treatment | |
| DE3762018D1 (en) | WASHABLE TOPICAL PREPARATION FOR THERAPY OF PSORIASIS. | |
| US5039515A (en) | Mouth cleansing preparation | |
| Statham et al. | Short‐contact dithranol therapy—a comparison with the Ingram regime | |
| ES2337359T3 (en) | EXFOLIATION PROCEDURE USED BY UREA. | |
| US20060222687A1 (en) | Topical anesthetic | |
| CA2322745A1 (en) | Method of treating neuroma pain | |
| SU1560215A1 (en) | Agent for treating gingivitis | |
| EP1061802A4 (en) | Topical carbamazepine formulations and methods of use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |