CA2165071A1 - Ocular Insert with Anchoring Protrusions - Google Patents

Ocular Insert with Anchoring Protrusions

Info

Publication number
CA2165071A1
CA2165071A1 CA2165071A CA2165071A CA2165071A1 CA 2165071 A1 CA2165071 A1 CA 2165071A1 CA 2165071 A CA2165071 A CA 2165071A CA 2165071 A CA2165071 A CA 2165071A CA 2165071 A1 CA2165071 A1 CA 2165071A1
Authority
CA
Canada
Prior art keywords
ocular insert
length
protrusions
anchoring protrusions
circular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2165071A
Other languages
French (fr)
Other versions
CA2165071C (en
Inventor
Sohrab Darougar
Alan L. Weiner
Padmanabh Pravinchandra Bhatt
Victor Albert Raul
David Clayton Gantner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Escalon Medical Corp
Original Assignee
Sohrab Darougar
Alan L. Weiner
Padmanabh Pravinchandra Bhatt
Victor Albert Raul
David Clayton Gantner
Escalon Ophthalmic, Inc.
Dow Corning Corporation
Intelligent Surgical Lasers, Inc.
Escalon Medical Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sohrab Darougar, Alan L. Weiner, Padmanabh Pravinchandra Bhatt, Victor Albert Raul, David Clayton Gantner, Escalon Ophthalmic, Inc., Dow Corning Corporation, Intelligent Surgical Lasers, Inc., Escalon Medical Corp. filed Critical Sohrab Darougar
Publication of CA2165071A1 publication Critical patent/CA2165071A1/en
Application granted granted Critical
Publication of CA2165071C publication Critical patent/CA2165071C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

A flexible ocular insert device adapted for the controlled sustained release of an ophthalmic drug into the eye. In one embodiment, the device includes an elongated body of a polymeric material in the form of a rod or tube containing a pharmaceutically active ingredient and with at least two anchoring protrusions extending radially outwardly from the body. The device has a length of at least 8 mm and the diameter of its body portion including the protrusions does not exceed 1.9 mm. As shown in Figure 7, the device (70) with ribbed configuration has circular cylindrical walls (72) with domed end portions (74). A series of arcuate shaped ribs (76), of circular, toroidal cross section, are provided at intervals along the length of the device (70).
CA002165071A 1993-06-29 1994-06-20 Ocular insert with anchoring protrusions Expired - Fee Related CA2165071C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/083,303 1993-06-29
US08/083,303 US5322691A (en) 1986-10-02 1993-06-29 Ocular insert with anchoring protrusions
PCT/US1994/007136 WO1995001764A2 (en) 1993-06-29 1994-06-20 Ocular insert with anchoring protrusions

Publications (2)

Publication Number Publication Date
CA2165071A1 true CA2165071A1 (en) 1995-01-19
CA2165071C CA2165071C (en) 2000-08-15

Family

ID=22177459

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002165071A Expired - Fee Related CA2165071C (en) 1993-06-29 1994-06-20 Ocular insert with anchoring protrusions

Country Status (5)

Country Link
US (2) US5322691A (en)
EP (1) EP0707464A4 (en)
JP (1) JP2995137B2 (en)
CA (1) CA2165071C (en)
WO (1) WO1995001764A2 (en)

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Also Published As

Publication number Publication date
CA2165071C (en) 2000-08-15
US5322691A (en) 1994-06-21
EP0707464A1 (en) 1996-04-24
WO1995001764A2 (en) 1995-01-19
WO1995001764A3 (en) 1995-03-02
EP0707464A4 (en) 1997-03-26
JP2995137B2 (en) 1999-12-27
US5395618A (en) 1995-03-07
JPH0767910A (en) 1995-03-14

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