CA2366778A1 - Methods for detecting nucleic acids indicative of cancer - Google Patents

Methods for detecting nucleic acids indicative of cancer Download PDF

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Publication number
CA2366778A1
CA2366778A1 CA002366778A CA2366778A CA2366778A1 CA 2366778 A1 CA2366778 A1 CA 2366778A1 CA 002366778 A CA002366778 A CA 002366778A CA 2366778 A CA2366778 A CA 2366778A CA 2366778 A1 CA2366778 A1 CA 2366778A1
Authority
CA
Canada
Prior art keywords
cancer
methods
nucleic acids
detecting nucleic
acids indicative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002366778A
Other languages
French (fr)
Other versions
CA2366778C (en
Inventor
Stanley N. Lapidus
Anthony P. Shuber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esoterix Genetic Laboratories LLC
Original Assignee
Exact Sciences Corporation
Stanley N. Lapidus
Anthony P. Shuber
Exact Laboratories, Inc.
Exact Corporation
Genzyme Corporation
Esoterix Genetic Laboratories, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exact Sciences Corporation, Stanley N. Lapidus, Anthony P. Shuber, Exact Laboratories, Inc., Exact Corporation, Genzyme Corporation, Esoterix Genetic Laboratories, Llc filed Critical Exact Sciences Corporation
Publication of CA2366778A1 publication Critical patent/CA2366778A1/en
Application granted granted Critical
Publication of CA2366778C publication Critical patent/CA2366778C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57473—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA

Abstract

The invention provides methods for screening tissue or body fluid samples for nucleic acid indicia of cancer or precancer.
CA002366778A 1999-04-09 2000-04-07 Methods for detecting nucleic acids indicative of cancer Expired - Fee Related CA2366778C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12862999P 1999-04-09 1999-04-09
US60/128,629 1999-04-09
PCT/US2000/009263 WO2000061808A2 (en) 1999-04-09 2000-04-07 Methods for detecting nucleic acids indicative of cancer

Publications (2)

Publication Number Publication Date
CA2366778A1 true CA2366778A1 (en) 2000-10-19
CA2366778C CA2366778C (en) 2008-07-22

Family

ID=22436245

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002366778A Expired - Fee Related CA2366778C (en) 1999-04-09 2000-04-07 Methods for detecting nucleic acids indicative of cancer

Country Status (9)

Country Link
US (5) US6964846B1 (en)
EP (1) EP1169479B1 (en)
JP (2) JP4794052B2 (en)
AT (1) ATE331811T1 (en)
AU (1) AU767983B2 (en)
CA (1) CA2366778C (en)
DE (1) DE60029092T2 (en)
ES (1) ES2269129T3 (en)
WO (1) WO2000061808A2 (en)

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US20090291436A1 (en) 2009-11-26
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US20100173320A1 (en) 2010-07-08
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AU4210500A (en) 2000-11-14

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