CA2376146A1 - Biopsy site marker and process and apparatus for applying it - Google Patents

Biopsy site marker and process and apparatus for applying it Download PDF

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Publication number
CA2376146A1
CA2376146A1 CA002376146A CA2376146A CA2376146A1 CA 2376146 A1 CA2376146 A1 CA 2376146A1 CA 002376146 A CA002376146 A CA 002376146A CA 2376146 A CA2376146 A CA 2376146A CA 2376146 A1 CA2376146 A1 CA 2376146A1
Authority
CA
Canada
Prior art keywords
gelatin
tube
biopsy site
typically
pellets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002376146A
Other languages
French (fr)
Other versions
CA2376146C (en
Inventor
Fred H. Burbank
Paul Lubock
Michael L. Jones
Nancy Forcier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SenoRx Inc
Original Assignee
Senorx, Inc.
Fred H. Burbank
Paul Lubock
Michael L. Jones
Nancy Forcier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senorx, Inc., Fred H. Burbank, Paul Lubock, Michael L. Jones, Nancy Forcier filed Critical Senorx, Inc.
Priority to CA2673620A priority Critical patent/CA2673620C/en
Publication of CA2376146A1 publication Critical patent/CA2376146A1/en
Application granted granted Critical
Publication of CA2376146C publication Critical patent/CA2376146C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3904—Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
    • A61B2090/3908—Soft tissue, e.g. breast tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3933—Liquid markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A61B2090/395—Visible markers with marking agent for marking skin or other tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3987—Applicators for implanting markers

Abstract

A biopsy site marker comprises small bodies or pellets (20) of gelatin which enclose substantially in their interior a radio (X-ray) opaque object. The gelatin pellets are deposited into the biopsy site, typically a cylindrical opening in the tissue created by the recent use of a vacuum assisted large core biopsy device, by an applicator device that includes an elongated cylindrical body that forms a flexible tube (26) and a piston (28) slidable in the tube. One end of the tube is placed into the biopsy site. Typically, sev-eral gelatin pellets, only some of which typically do, but all of which may contain the radio opaque object, are deposited sequentially into the site through the tube. The radio opaque objects contained in the gelatin bodies are of a non-biological configuration and readily identifiable as man-made object, so that in observation by typical mammography equipment they do not assume the shape of a line, whereby they are readily distinguishable from granules and lines of calcification.
CA002376146A 1999-06-30 2000-06-28 Biopsy site marker and process and apparatus for applying it Expired - Lifetime CA2376146C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2673620A CA2673620C (en) 1999-06-30 2000-06-28 Biopsy site marker and process and apparatus for applying it

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/343,975 1999-06-30
US09/343,975 US6347241B2 (en) 1999-02-02 1999-06-30 Ultrasonic and x-ray detectable biopsy site marker and apparatus for applying it
PCT/US2000/017906 WO2001000101A1 (en) 1999-06-30 2000-06-28 Biopsy site marker and process and apparatus for applying it

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2673620A Division CA2673620C (en) 1999-06-30 2000-06-28 Biopsy site marker and process and apparatus for applying it

Publications (2)

Publication Number Publication Date
CA2376146A1 true CA2376146A1 (en) 2001-01-04
CA2376146C CA2376146C (en) 2009-09-29

Family

ID=23348485

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2673620A Expired - Lifetime CA2673620C (en) 1999-06-30 2000-06-28 Biopsy site marker and process and apparatus for applying it
CA002376146A Expired - Lifetime CA2376146C (en) 1999-06-30 2000-06-28 Biopsy site marker and process and apparatus for applying it

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2673620A Expired - Lifetime CA2673620C (en) 1999-06-30 2000-06-28 Biopsy site marker and process and apparatus for applying it

Country Status (9)

Country Link
US (4) US6347241B2 (en)
EP (3) EP1974686A3 (en)
JP (1) JP2003503098A (en)
AT (2) ATE406141T1 (en)
AU (1) AU5777500A (en)
CA (2) CA2673620C (en)
DE (2) DE60040104D1 (en)
ES (2) ES2237435T3 (en)
WO (1) WO2001000101A1 (en)

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US6347241B2 (en) 2002-02-12
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