CA2418669A1 - Apparatus and method for regulating fluid pump pressures - Google Patents

Apparatus and method for regulating fluid pump pressures Download PDF

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Publication number
CA2418669A1
CA2418669A1 CA002418669A CA2418669A CA2418669A1 CA 2418669 A1 CA2418669 A1 CA 2418669A1 CA 002418669 A CA002418669 A CA 002418669A CA 2418669 A CA2418669 A CA 2418669A CA 2418669 A1 CA2418669 A1 CA 2418669A1
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CA
Canada
Prior art keywords
pressure
liquid volume
liquid
fluid
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002418669A
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French (fr)
Other versions
CA2418669C (en
Inventor
Larry B. Gray
Robert Bryant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deka Products LP
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Individual
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Application filed by Individual filed Critical Individual
Publication of CA2418669A1 publication Critical patent/CA2418669A1/en
Application granted granted Critical
Publication of CA2418669C publication Critical patent/CA2418669C/en
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Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/06—Pumps having fluid drive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/155—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with treatment-fluid pumping means or components thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
    • A61M1/1565—Details of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/159—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit specially adapted for peritoneal dialysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A61M1/282—Operational modes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16809—Flow controllers by repeated filling and emptying of an intermediate volume
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D16/00—Control of fluid pressure
    • G05D16/20—Control of fluid pressure characterised by the use of electric means
    • G05D16/2006—Control of fluid pressure characterised by the use of electric means with direct action of electric energy on controlling means
    • G05D16/2066—Control of fluid pressure characterised by the use of electric means with direct action of electric energy on controlling means using controlling means acting on the pressure source
    • G05D16/2073—Control of fluid pressure characterised by the use of electric means with direct action of electric energy on controlling means using controlling means acting on the pressure source with a plurality of pressure sources
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/06—Control of flow characterised by the use of electric means
    • G05D7/0617—Control of flow characterised by the use of electric means specially adapted for fluid materials
    • G05D7/0629—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means
    • G05D7/0635—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means by action on throttling means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/152—Details related to the interface between cassette and machine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes

Abstract

A method is provided for regulating fluid pump pressures by detecting an elevation differential between a fluid flow control device and the distal end of a fluid line in communication with the fluid flow control device. A fluid flow control device, for instance a peritoneal dialysis device, is at a first height, a distal end of a fluid line is at a second height, and a valued outlet, when open, affords communication between the fluid flow control device and the distal end of the fluid line. The elevation differential is correlatable with a pressure measurable during a calibration procedure provided as a part of the methodology.

Claims (28)

1. A method for regulating fluid pump pressures, the method comprising:
providing a fluid flow control device, the fluid flow control device having at least one liquid volume in valued communication with a distal end of a fluid line;
calibrating the pressure in the liquid volume;
establishing communication between the liquid volume and the distal end;
measuring a pressure associated with the liquid volume; and adjusting the fluid pump pressure in accordance with the measured pressure.
2. A method according to Claim 1, wherein calibrating the liquid volume comprises:
isolating the liquid volume from the distal end;
measuring a first calibration pressure of a control volume in pressure communication with the liquid volume;
pressurizing the liquid volume; and measuring a second calibration pressure of the control volume.
3. A method according to Claim 1, wherein calibrating the liquid volume comprises:
isolating the liquid volume from the distal end;
measuring the pressure of a control volume in pressure communication with the liquid volume;
positively pressurizing the liquid volume;
measuring the pressure of the control volume while the liquid volume is positively pressurized;
negatively pressurizing the liquid volume; and measuring the pressure of the control volume while the liquid volume is negatively pressurized.
4. A method according to Claim 1, wherein the liquid volume includes a flexible membrane, which separates the liquid volume from a control volume where pressure measurements are made.
5. A method according to Claim 1, wherein the fluid flow control device includes a pump.
6. A method for regulating fluid pump pressures, the method comprising:
providing a fluid flow control device, the fluid flow control device having a first liquid volume and a second liquid volume, the first liquid volume in valued communication with the second liquid volume;
providing a fluid line, the fluid line having a distal end in valued communication with the first liquid volume and the second liquid volume;
calibrating the pressures in the liquid volumes;
establishing communication between the first liquid volume and the distal end;
measuring a pressure associated with the first liquid volume;
adjusting the fluid pump pressure in accordance with the measured pressure.
7. A method according to Claim 6, wherein calibrating the liquid volumes comprises:
isolating the liquid volumes from the distal end;
measuring first calibration pressures associated with the first liquid volume and the second liquid volume;
pressurizing the first liquid volume;
measuring a second calibration pressure associated with the second liquid volume; and adjusting the fluid pump pressure in accordance with the measured pressures.
8. A method according to Claim 6, wherein calibrating the liquid volumes comprises:
isolating the liquid volumes from the distal end;
measuring first calibration pressures associated with the first liquid volume and the second liquid volume;
positively pressurizing the first liquid volume;
measuring a second calibration pressure associated with the second liquid volume while the first liquid volume is positively pressurized;
negatively pressurizing the first liquid volume;
measuring a third calibration pressure associated with the second liquid volume while the first liquid volume is negatively pressurized; and adjusting the fluid pump pressure in accordance with the measured pressures.
9. A method according to Claim 6, wherein each of the first and second liquid volumes includes a flexible membrane that separates the liquid volume from a control volume, and wherein the pressure measurements are taken from the control volume.
10. A method according to Claim 6, wherein the first and second liquid volumes are disposed within a cassette.
11. A method according to Claim 10, wherein the fluid flow control device includes a pump.
12. A method for estimating the relative elevation between a first location and a second location, the method comprising:
placing a fluid flow control device at the first location, the fluid flow control device having a membrane pump in valued communication with the second location, the membrane pump having a pressure transducer;
isolating the membrane pump from the second location;

calibrating the pressure transducer;
establishing communication between the membrane pump and the second location;
measuring the pressure in the membrane pump with the pressure transducer; and estimating the relative elevation based on the pressure.
13. A method according to Claim 12, wherein calibrating the pressure transducer comprises:
filling the membrane pump with fluid in pressure equilibrium with the pressure at the first location;
measuring a first calibration pressure in the membrane pump;
filling the membrane pump with fluid in pressure equilibrium with a known calibration pressure;
measuring a second calibration pressure in the membrane pump; and estimating the relative elevation by constructing a linear fit between pressure and relative elevation based on the known calibration pressure, the first calibration pressure, and the second calibration pressure.
14. A method according to Claim 13, wherein the relative elevation is determined by a processor.
15. A computer program product for use on a processor for determining an elevation differential between a first location and a second location, wherein a fluid flow control device is located at the first location, the fluid flow control device including at least one liquid volume in valued communication with a second location via a distal end of a fluid line, the computer program product comprising a computer usable medium having computer readable program code thereon, the computer readable program code including:
program code for reading and storing pressure values within the pumps;
program code for computing and identifying correlations between stored pressure values;
program code for calculating pressure values based on the identified correlations; and program code for estimating the elevation differential based upon the calculated pressures.
16. The computer program product according to Claim 15, further comprising:
program code for calculating a desired pumping pressure based upon the elevation differential; and program code for adjusting the pumping pressured withing the fluid flow control device in accordance with the desired pumping pressure.
17. A computer program product for use on a processor for regulating fluid pump pressures, wherein a fluid flow control device is located at the first location, the fluid flow control device including at least one liquid volume in valued communication with a second location via a distal end of a fluid line, the computer program product comprising a computer usable medium having computer readable program code thereon, the computer readable program code including:
program code for reading and storing pressure values within the pumps;
program code for computing and identifying correlations between stored pressure values;
program code for calculating pressure values based on the identified correlations; and program code for calculating a desired pumping pressure based on the identified correlations.
18. A fluid flow control device for detecting an elevation differential between a first location and a second location, wherein the device is located at the first location, the fluid flow control device comprising:

at least one liquid volume;
a fluid line in valued pressure communication with the liquid volume, the fluid line having a distal end located at the second location;
at least one transducer for measuring pressure associated with the liquid volume; and a processor for:
reading and storing pressure values;
computing and identifying a correlation between the pressure values;
calculating pressure values based on the identified correlations; and estimating the elevation differential based upon the calculated pressures.
19. A device according to Claim 18, wherein the correlation computed and identified is a linear fit.
20. A device according to Claim 18, wherein the liquid volume includes a flexible membrane that separates the liquid volume from a control volume, and wherein the pressure measurements are taken from the control volume.
21. A device according to Claim 18, wherein the liquid volume is disposed within a cassette.
22. A device according to Claim 18, further comprising at least one pump.
23. A device according to Claim 18, further comprising at least one piston.
24. A system for regulating fluid pump pressures, the system comprising:
a fluid flow control device having at least one liquid volume in valued communication with a distal end of a fluid line, the fluid flow control device including pressure means for pressurizing the liquid volume;

a valve arrangement for controlling fluid communication between the at least one liquid volume and the distal end;
a transducer for measuring a pressure associated with the at least one liquid volume; and a controller for controlling the valve arrangement, the means for pressurizing the liquid volume, and the fluid pump pressure, and wherein the controller adjusts the fluid pump pressure in accordance with the pressure measured by the transducer.
25. A system for regulating fluid pump pressures, the system comprising:
a fluid flow control device having first and second liquid volumes in valued communication with each other and with a distal end of a fluid line, the fluid flow control device including means for pressurizing at least one liquid volume;
a valve arrangement for controlling fluid communication between the liquid volumes and between the liquid volumes and the distal end;
a transducer for measuring a pressure associated with at least one liquid volume; and a controller for controlling the valve arrangement, the means for pressurizing the liquid volumes, and the fluid pump pressure, and wherein the controller adjusts the fluid pump pressure in accordance with the pressure measured by the transducer.
26. A system according to Claim 25, wherein the controller causes:
the valve arrangement to isolate the liquid volumes from the distal end;
the transducer to measure the pressure associated with the first liquid volume, while it is isolated from the distal end;
the means for pressurizing the second liquid volume; and measuring the pressure associated with the first liquid volume after the pressure in the second liquid volume has been pressurized.
27. A system according to Claim 25, wherein the liquid volumes include a flexible membrane.
28. A system according to Claim 27, wherein at least one liquid volume is disposed within a cassette.
CA2418669A 2000-07-10 2001-06-25 Apparatus and method for regulating fluid pump pressures Expired - Lifetime CA2418669C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/612,005 2000-07-10
US09/612,005 US6503062B1 (en) 2000-07-10 2000-07-10 Method for regulating fluid pump pressure
PCT/US2001/041131 WO2003011376A2 (en) 2000-07-10 2001-06-25 Apparatus and method for regulating fluid pump pressures

Publications (2)

Publication Number Publication Date
CA2418669A1 true CA2418669A1 (en) 2003-02-13
CA2418669C CA2418669C (en) 2011-10-18

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ID=24451321

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Application Number Title Priority Date Filing Date
CA2418669A Expired - Lifetime CA2418669C (en) 2000-07-10 2001-06-25 Apparatus and method for regulating fluid pump pressures

Country Status (10)

Country Link
US (6) US6503062B1 (en)
EP (2) EP2289577A1 (en)
JP (2) JP4900887B2 (en)
AU (1) AU2001298000A1 (en)
BR (1) BRPI0112320B8 (en)
CA (1) CA2418669C (en)
DE (1) DE60142797D1 (en)
MX (1) MXPA03000328A (en)
TW (1) TW506840B (en)
WO (1) WO2003011376A2 (en)

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