CA2548696A1 - Silicon dioxide coating for medical implants - Google Patents
Silicon dioxide coating for medical implants Download PDFInfo
- Publication number
- CA2548696A1 CA2548696A1 CA002548696A CA2548696A CA2548696A1 CA 2548696 A1 CA2548696 A1 CA 2548696A1 CA 002548696 A CA002548696 A CA 002548696A CA 2548696 A CA2548696 A CA 2548696A CA 2548696 A1 CA2548696 A1 CA 2548696A1
- Authority
- CA
- Canada
- Prior art keywords
- coating
- medical implant
- substrate
- silicon dioxide
- implant according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00161—Carbon; Graphite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00598—Coating or prosthesis-covering structure made of compounds based on metal oxides or hydroxides
- A61F2310/00604—Coating made of aluminium oxide or hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00598—Coating or prosthesis-covering structure made of compounds based on metal oxides or hydroxides
- A61F2310/00616—Coating made of titanium oxide or hydroxides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/26—Web or sheet containing structurally defined element or component, the element or component having a specified physical dimension
Abstract
The invention is directed towards a coating for medical implants, in particular, vascular stents, said coating comprising silicon dioxide, towards medical implants with a coating containi ng silicon dioxide and towards a method for their production. The coating can contain additional admixtures and have functionalisation coats. The substrate of the coating is produced from a durable material, preferably from a stainless steel.
Claims (21)
1. Coating for medical implants, said coating comprising silicon dioxide.
2. Coating according to Claim 1, characterised in that the medical implant is a vascular stent.
3. Coating according to Claim 1 or 2, characterised in that the coating contains an admixture that is selected from aluminium oxide, titanium oxide, calcium compounds, sodium oxide, germanium oxide, magnesium oxide, selenium oxide and hydroxides, particularly hydroxides of the previously mentioned metals, and mixtures of the same.
4. Coating according to Claim 3, characterised in that a ratio of the admixture to the total quantity of the coating amounts to 0.5 to 50 % by weight.
5. Coating according to one of the Claims 1 to 4, characterised in that the coating is essentially pore-free.
6. Coating according to one of the Claims 1 to 4, characterised in that the coating has pores for functionalisation.
7. Coating according to one of the Claims 1 to 6, characterised in that the coating contains an additional functionalisation coat.
8. Coating according to Claim 7, characterised in that the functionalisation coat comprises at least one medicine and / or at least one cell poison.
9. Coating according to one of the Claims 1 to 8, characterised in that the thickness of the coating is 0.1 to 1000 nm.
10. Coating according to one of the Claims 1 to 9, characterised in that the coating consists of multiple, successively applied layers.
11. Medical implant comprising a substrate that forms a basic structure and a coating that is applied to at least sections of the substrate and that contains silicon dioxide.
12. Medical implant according to Claim 11, characterised in that it is a vascular stent.
13. Medical implant according to Claim 11 or 12, characterised in that the coating is a coating according to one of the Claims 1 to 10.
14. Medical implant according to one of the Claims 11 to 13, characterised in that the substrate is constructed of a difficult-to-degrade material.
15. Medical implant according to one of the Claims 11 to 14, characterised in that the substrate comprises carbon, PTFE, Dacron, metal alloys, PHA.
16. Medical implant according to Claim 15, characterised in that the substrate comprises iron alloys.
17. Medical implant according to Claim 16, characterised in that the iron alloy is a stainless steel.
18. Medical implant according to Claim 14, characterised in that the substrate comprises a shape memory metal, in particular, nickel-titanium alloys.
19. Medical implant according to one of the Claims 12 to 18, characterised in that the vascular stent is intended for a blood vessel, a bile duct, the oesophagus or the trachea.
20. Method for the production of a coated medical implant, in particular of a medical implant according to one of the Claims 11 to 19, having the steps:
- provision of a substrate forming the basic structure; and - application of a coating containing silicon dioxide by means of a plasma coating method.
- provision of a substrate forming the basic structure; and - application of a coating containing silicon dioxide by means of a plasma coating method.
21. Method according to Claim 20, characterised in that it furthermore comprises the production of pores in the coating by means of neutron bombardment or laser light.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005024913.2 | 2005-05-31 | ||
DE102005024913A DE102005024913A1 (en) | 2005-05-31 | 2005-05-31 | Stent for insertion into vessel, comprises specifically applied coating for avoidance of new blockage |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2548696A1 true CA2548696A1 (en) | 2006-11-30 |
CA2548696C CA2548696C (en) | 2011-11-22 |
Family
ID=37439850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2548696A Expired - Fee Related CA2548696C (en) | 2005-05-31 | 2006-05-30 | Silicon dioxide coating for medical implants |
Country Status (5)
Country | Link |
---|---|
US (2) | US8105374B2 (en) |
JP (1) | JP2006334406A (en) |
AU (2) | AU2006202205A1 (en) |
CA (1) | CA2548696C (en) |
DE (1) | DE102005024913A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7702764B1 (en) * | 2004-01-30 | 2010-04-20 | Cisco Technology, Inc. | System and method for testing network protocols |
DE102005024913A1 (en) * | 2005-05-31 | 2006-12-14 | Axetis Ag | Stent for insertion into vessel, comprises specifically applied coating for avoidance of new blockage |
US20070112421A1 (en) * | 2005-11-14 | 2007-05-17 | O'brien Barry | Medical device with a grooved surface |
US20080234810A1 (en) * | 2006-06-28 | 2008-09-25 | Abbott Cardiovascular Systems Inc. | Amorphous Glass-Coated Drug Delivery Medical Device |
DE602007011822D1 (en) * | 2006-11-16 | 2011-02-17 | Boston Scient Ltd | STENT WITH FUNCTION FOR DIFFERENT TIMES OF ABLUMINAL AND LUMINOUS RELEASE OF A TREATMENT |
DE102007032686A1 (en) * | 2007-07-13 | 2009-01-15 | Biotronik Vi Patent Ag | Stent with a coating |
DE102007042451A1 (en) * | 2007-09-06 | 2009-03-12 | Biotronik Vi Patent Ag | Stent with a body made of a biocorrodible alloy |
US20090076591A1 (en) * | 2007-09-19 | 2009-03-19 | Boston Scientific Scimed, Inc. | Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface |
US7833266B2 (en) | 2007-11-28 | 2010-11-16 | Boston Scientific Scimed, Inc. | Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment |
US7951193B2 (en) * | 2008-07-23 | 2011-05-31 | Boston Scientific Scimed, Inc. | Drug-eluting stent |
CH706803A1 (en) * | 2012-08-06 | 2014-02-14 | Axetis Ag | A coated stent. |
WO2014058589A1 (en) * | 2012-10-08 | 2014-04-17 | Cormatrix Cardiovascular, Inc. | Multi-layer vascular prosthesis |
EP3040090B1 (en) | 2014-12-31 | 2019-05-29 | Cook Medical Technologies LLC | Medical devices and methods of making |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS573739A (en) * | 1980-06-11 | 1982-01-09 | Nippon Kogaku Kk <Nikon> | Bioactive glass and glass ceramic |
EP0401793B1 (en) * | 1989-06-06 | 1995-10-04 | TDK Corporation | Use of ceramic materials for living hard tissue replacements |
JPH06112133A (en) * | 1992-09-25 | 1994-04-22 | Nippon Sheet Glass Co Ltd | Method of covering upper section of base body with transparent dielectric film |
DE19506188C2 (en) * | 1995-02-22 | 2003-03-06 | Miladin Lazarov | Implant and its use |
US6774278B1 (en) * | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
EP0792688A1 (en) * | 1996-03-01 | 1997-09-03 | Dow Corning Corporation | Nanoparticles of silicon oxide alloys |
CA2241678C (en) * | 1997-06-26 | 2007-08-28 | General Electric Company | Silicon dioxide deposition by plasma activated evaporation process |
US20020099438A1 (en) * | 1998-04-15 | 2002-07-25 | Furst Joseph G. | Irradiated stent coating |
JPH11299901A (en) * | 1998-04-16 | 1999-11-02 | Johnson & Johnson Medical Kk | Stent and its manufacture |
EP1175236A1 (en) | 1999-04-23 | 2002-01-30 | Agion Technologies, L.L.C. | Stent having antimicrobial agent |
FI19991852A (en) | 1999-09-01 | 2001-03-01 | Yli Urpo Antti | New multilayer material with a biologically active agent, and its preparation |
AU2023301A (en) * | 2000-01-03 | 2001-07-16 | Ory Keynan | Improved prosthesis |
US20020018851A1 (en) * | 2000-06-21 | 2002-02-14 | Edward Chang | Manufacturing method for surgical implants having a layer of bioactive ceramic coating |
US6716444B1 (en) * | 2000-09-28 | 2004-04-06 | Advanced Cardiovascular Systems, Inc. | Barriers for polymer-coated implantable medical devices and methods for making the same |
US7261735B2 (en) | 2001-05-07 | 2007-08-28 | Cordis Corporation | Local drug delivery devices and methods for maintaining the drug coatings thereon |
DE10123442C2 (en) | 2001-03-23 | 2003-05-22 | Alcove Surfaces Gmbh | operation tool |
DE10123441C2 (en) | 2001-03-23 | 2003-08-14 | Alcove Surfaces Gmbh | Implant in the form of a stent |
EP1381402B1 (en) * | 2001-04-27 | 2009-11-18 | Vivoxid Oy | Method for improvement of soft tissue attachment and implants making use of said method |
US6945994B2 (en) * | 2001-12-05 | 2005-09-20 | Boston Scientific Scimed, Inc. | Combined balloon-expanding and self-expanding stent |
US7387742B2 (en) * | 2002-03-11 | 2008-06-17 | Becton, Dickinson And Company | Silicon blades for surgical and non-surgical use |
JP2003305124A (en) * | 2002-04-15 | 2003-10-28 | Takehisa Matsuda | Stent with disseminated cell |
DE10230720A1 (en) * | 2002-07-08 | 2004-02-12 | Tinox Ag I.Ins. | Implant for use in human or animal, e.g. stent, has surface of e.g. glass, glass ceramic, cermet or metal alloy with low angle of contact with water and coating containing albumen |
DE10243092B4 (en) | 2002-07-17 | 2006-04-27 | Alcove Surfaces Gmbh | Surgical device used as operating tool for humans and animals comprises base material covered with barrier layer made from amorphous hypostoichiometric silicon oxide and having specified average Vickers hardness and elastic modulus |
DK1405647T3 (en) | 2002-10-03 | 2006-06-26 | Vivoxid Oy | Bioactive glass composition |
CA2500823A1 (en) * | 2002-10-03 | 2004-04-15 | Vivoxid Oy | Composition, use and manufacture of bioactive glass |
CA2448592C (en) | 2002-11-08 | 2011-01-11 | Howmedica Osteonics Corp. | Laser-produced porous surface |
US20050038498A1 (en) * | 2003-04-17 | 2005-02-17 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
ATE316801T1 (en) * | 2003-11-07 | 2006-02-15 | Eska Implants Gmbh & Co | JOINT DOPROSTHESIS WITH METALLIC CORE AND GLASS CERAMIC COATING |
US20050165487A1 (en) * | 2004-01-28 | 2005-07-28 | Muhanna Nabil L. | Artificial intervertebral disc |
US7981441B2 (en) * | 2004-02-18 | 2011-07-19 | The Board Of Trustees Of The Leland Stanford Junior University | Drug delivery systems using mesoporous oxide films |
US20050209670A1 (en) * | 2004-03-02 | 2005-09-22 | Cardiomind, Inc. | Stent delivery system with diameter adaptive restraint |
DE102005024913A1 (en) * | 2005-05-31 | 2006-12-14 | Axetis Ag | Stent for insertion into vessel, comprises specifically applied coating for avoidance of new blockage |
-
2005
- 2005-05-31 DE DE102005024913A patent/DE102005024913A1/en not_active Withdrawn
-
2006
- 2006-05-25 AU AU2006202205A patent/AU2006202205A1/en not_active Abandoned
- 2006-05-30 CA CA2548696A patent/CA2548696C/en not_active Expired - Fee Related
- 2006-05-31 JP JP2006152258A patent/JP2006334406A/en active Pending
- 2006-05-31 US US11/443,717 patent/US8105374B2/en not_active Expired - Fee Related
-
2008
- 2008-12-24 AU AU2008264179A patent/AU2008264179B2/en not_active Ceased
-
2012
- 2012-01-31 US US13/362,477 patent/US8911857B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2008264179A1 (en) | 2009-01-29 |
AU2006202205A1 (en) | 2006-12-14 |
CA2548696C (en) | 2011-11-22 |
DE102005024913A1 (en) | 2006-12-14 |
US8105374B2 (en) | 2012-01-31 |
US20120130482A1 (en) | 2012-05-24 |
US8911857B2 (en) | 2014-12-16 |
JP2006334406A (en) | 2006-12-14 |
AU2008264179B2 (en) | 2012-03-01 |
US20070100438A1 (en) | 2007-05-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2548696A1 (en) | Silicon dioxide coating for medical implants | |
Amukarimi et al. | Biodegradable magnesium‐based biomaterials: An overview of challenges and opportunities | |
Li et al. | Biodegradable Mg–Zn–Ca–Sr bulk metallic glasses with enhanced corrosion performance for biomedical applications | |
JP6678982B2 (en) | Bioabsorbable stent | |
Toong et al. | Bioresorbable metals in cardiovascular stents: Material insights and progress | |
US8216632B2 (en) | Endoprosthesis coating | |
Tian et al. | In vitro degradation behavior and cytocompatibility of biodegradable AZ31 alloy with PEO/HT composite coating | |
US20090164002A1 (en) | Implant with a base body of a biocorrodible alloy | |
CN110234366A (en) | High functional biological bioabsorbable stent | |
US10960110B2 (en) | Iron-based biodegradable metals for implantable medical devices | |
US11284988B2 (en) | Method for producing biocorrodible magnesium alloy implant | |
US20080177371A1 (en) | Implantable devices and methods of forming the same | |
Zhao et al. | Functionalization of biomedical materials using plasma and related technologies | |
EP2101835B1 (en) | Metal implants | |
US8801778B2 (en) | Implant with a base body of a biocorrodible alloy | |
TWI513480B (en) | Magnesium alloy suitable for medical implants and method for manufacturing the same | |
Schmitz | Functional coatings by physical vapor deposition (PVD) for biomedical applications | |
Istrate et al. | Current Research Studies of Mg–Ca–Zn Biodegradable Alloys Used as Orthopedic Implants—Review. Crystals 2022, 12, 1468 | |
Hu et al. | Recent Developments of Zn-based Medical Implants | |
Morales | Antibacterial and biocompatible titanium-copper oxide coating may be a potential strategy to reduce periprosthetic infection: An in vitro study |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20180530 |
|
MKLA | Lapsed |
Effective date: 20180530 |