CA2567403A1 - Interspinous spacer - Google Patents
Interspinous spacer Download PDFInfo
- Publication number
- CA2567403A1 CA2567403A1 CA002567403A CA2567403A CA2567403A1 CA 2567403 A1 CA2567403 A1 CA 2567403A1 CA 002567403 A CA002567403 A CA 002567403A CA 2567403 A CA2567403 A CA 2567403A CA 2567403 A1 CA2567403 A1 CA 2567403A1
- Authority
- CA
- Canada
- Prior art keywords
- spacer
- configuration
- hydrogel
- collapsed configuration
- profile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 125000006850 spacer group Chemical group 0.000 title claims abstract description 224
- 238000000034 method Methods 0.000 claims abstract description 98
- 230000008569 process Effects 0.000 claims abstract description 37
- 238000002513 implantation Methods 0.000 claims abstract description 30
- 230000000903 blocking effect Effects 0.000 claims abstract description 24
- 238000000926 separation method Methods 0.000 claims abstract description 3
- 229920002635 polyurethane Polymers 0.000 claims description 32
- 239000004814 polyurethane Substances 0.000 claims description 32
- 239000000017 hydrogel Substances 0.000 claims description 26
- 239000007943 implant Substances 0.000 claims description 26
- 229920001296 polysiloxane Polymers 0.000 claims description 15
- 229910052751 metal Inorganic materials 0.000 claims description 14
- 239000002184 metal Substances 0.000 claims description 14
- 239000003381 stabilizer Substances 0.000 claims description 11
- 239000002831 pharmacologic agent Substances 0.000 claims description 10
- 230000005489 elastic deformation Effects 0.000 claims description 6
- 150000004676 glycans Chemical class 0.000 claims description 6
- 229920001282 polysaccharide Polymers 0.000 claims description 6
- 239000005017 polysaccharide Substances 0.000 claims description 6
- 230000002441 reversible effect Effects 0.000 claims description 6
- 102000008186 Collagen Human genes 0.000 claims description 5
- 108010035532 Collagen Proteins 0.000 claims description 5
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 5
- 229920002367 Polyisobutene Polymers 0.000 claims description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 5
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 claims description 5
- 125000001931 aliphatic group Chemical group 0.000 claims description 5
- 229940035676 analgesics Drugs 0.000 claims description 5
- 239000000730 antalgic agent Substances 0.000 claims description 5
- 239000003242 anti bacterial agent Substances 0.000 claims description 5
- 229940124599 anti-inflammatory drug Drugs 0.000 claims description 5
- 229940088710 antibiotic agent Drugs 0.000 claims description 5
- 229920001436 collagen Polymers 0.000 claims description 5
- 229920001577 copolymer Polymers 0.000 claims description 5
- 229910001000 nickel titanium Inorganic materials 0.000 claims description 5
- 229920001084 poly(chloroprene) Polymers 0.000 claims description 5
- 229920002401 polyacrylamide Polymers 0.000 claims description 5
- 229920001692 polycarbonate urethane Polymers 0.000 claims description 5
- -1 polyether-urethane Polymers 0.000 claims description 5
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 claims description 5
- 229920001195 polyisoprene Polymers 0.000 claims description 5
- 229920000098 polyolefin Polymers 0.000 claims description 5
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 5
- 150000003431 steroids Chemical class 0.000 claims description 5
- 239000004636 vulcanized rubber Substances 0.000 claims description 5
- 150000002825 nitriles Chemical class 0.000 claims description 4
- 239000003102 growth factor Substances 0.000 claims description 2
- 239000013536 elastomeric material Substances 0.000 claims 12
- 239000004433 Thermoplastic polyurethane Substances 0.000 claims 4
- 229920002803 thermoplastic polyurethane Polymers 0.000 claims 4
- 229920003052 natural elastomer Polymers 0.000 claims 2
- 229920001194 natural rubber Polymers 0.000 claims 2
- 229920003051 synthetic elastomer Polymers 0.000 claims 2
- 239000005061 synthetic rubber Substances 0.000 claims 2
- 229920000459 Nitrile rubber Polymers 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 229920000515 polycarbonate Polymers 0.000 claims 1
- 239000004417 polycarbonate Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 description 11
- 238000001356 surgical procedure Methods 0.000 description 10
- 208000005198 spinal stenosis Diseases 0.000 description 7
- 208000002193 Pain Diseases 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 238000001727 in vivo Methods 0.000 description 3
- 230000032683 aging Effects 0.000 description 2
- 210000000436 anus Anatomy 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 238000002684 laminectomy Methods 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 210000000278 spinal cord Anatomy 0.000 description 2
- 210000001032 spinal nerve Anatomy 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 102000007350 Bone Morphogenetic Proteins Human genes 0.000 description 1
- 108010007726 Bone Morphogenetic Proteins Proteins 0.000 description 1
- 102000018233 Fibroblast Growth Factor Human genes 0.000 description 1
- 108050007372 Fibroblast Growth Factor Proteins 0.000 description 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 description 1
- 206010061246 Intervertebral disc degeneration Diseases 0.000 description 1
- 102100026632 Mimecan Human genes 0.000 description 1
- 101800002327 Osteoinductive factor Proteins 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 description 1
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 description 1
- 206010037779 Radiculopathy Diseases 0.000 description 1
- 208000008765 Sciatica Diseases 0.000 description 1
- 102000013275 Somatomedins Human genes 0.000 description 1
- 208000007156 Spondylarthritis Diseases 0.000 description 1
- 240000004543 Vicia ervilia Species 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940112869 bone morphogenetic protein Drugs 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 206010007821 cauda equina syndrome Diseases 0.000 description 1
- 230000000991 decompressive effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 208000018180 degenerative disc disease Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 229940126864 fibroblast growth factor Drugs 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 229920001477 hydrophilic polymer Polymers 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000021600 intervertebral disc degenerative disease Diseases 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 206010025005 lumbar spinal stenosis Diseases 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 208000037959 spinal tumor Diseases 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000003867 tiredness Effects 0.000 description 1
- 208000016255 tiredness Diseases 0.000 description 1
- 210000002517 zygapophyseal joint Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7062—Devices acting on, attached to, or simulating the effect of, vertebral processes, vertebral facets or ribs ; Tools for such devices
- A61B17/7065—Devices with changeable shape, e.g. collapsible or having retractable arms to aid implantation; Tools therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30069—Properties of materials and coating materials elastomeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/3008—Properties of materials and coating materials radio-opaque, e.g. radio-opaque markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30092—Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30159—Concave polygonal shapes
- A61F2002/30166—H-shaped or I-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30471—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30565—Special structural features of bone or joint prostheses not otherwise provided for having spring elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30579—Special structural features of bone or joint prostheses not otherwise provided for with mechanically expandable devices, e.g. fixation devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2002/4635—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor using minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0091—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
Abstract
A spacer for maintaining separation between adjacent spinous processes has a collapsed and an expanded configuration. The collapsed configuration presents a smaller profile to facilitate minimally invasive implantation of the spacer.
An exemplary interspinous spacer (10) includes a blocking member 15 and arms 11, 12, 13 and 14. When the spacer is in its relaxed (expaded) configuration it resembles an "H", with arms 11, 12 , 13 and 14 being the legs of the H, and blocking member 15 being the crossbar. To use the spacer, the arms are manipulated to be parallel to the blocking member, manipulating the spacer to its collapsed (implantable) configuration. The manipulation makes the spacer assume the shape of an "I" rather than the shape of an "H" .
An exemplary interspinous spacer (10) includes a blocking member 15 and arms 11, 12, 13 and 14. When the spacer is in its relaxed (expaded) configuration it resembles an "H", with arms 11, 12 , 13 and 14 being the legs of the H, and blocking member 15 being the crossbar. To use the spacer, the arms are manipulated to be parallel to the blocking member, manipulating the spacer to its collapsed (implantable) configuration. The manipulation makes the spacer assume the shape of an "I" rather than the shape of an "H" .
Description
INTERSPINOUS SPACER
FIELD OF THE INVENTION
The present invention relates generally to devices for treating spinal stenosis, and more particularly to interspinous spacers that can be implanted in a minimally invasive manner to treat spinal stenosis.
BACKGROUND OF THE INVENTION
Lumbar spinal stenosis ("LSS", and sometimes called sciatica) is a condition of the spine characterized by a narrowing of the lumbar spinal canal. With spinal stenosis, the spinal canal narrows and pinches the spinal cord and nerves, causing pain in the back and legs. It is estimated that approximately 5 in 10,000 people develop LSS each year. For patients who seek the aid of a physician specialist for back pain, approximately 12-15%
are diagnosed as having LSS.
Several causes of spinal stenosis have been identified, including aging, heredity, arthritis, and changes in blood flow to the lower spine. Aging is believed to be the most common cause, because as a person ages the ligaments coimecting the bones of the spine can thicken and spurs may develop on the bones and into the spinal canal. The cushioning discs between the vertebrae also frequently deteriorate, and the facet joints may begin to break down. Heredity is believed to play a role in some cases because it may cause some people to have a smaller than average spinal canal, typically leading to LSS
symptoms even at a relatively young age.
The most common symptoms of spinal stenosis is pain and difficulty when walking, although nunibness, tingling, hot or cold feelings in the legs, and wealaiess or tiredness may also be experienced. In extreme cases spinal stenosis can cause cauda equina syndrome, a syndrome characterized by neuromuscular dysfunction that may result in permanent i}erve dainage.
Common treatinents for LSS include pliysical therapy (including changes in posture), medication, and occasionally surgeiy. Changes in posture and physical tlierapy may be effective in flexing the spine to enlarge the space available to the spinal cord and nerves - thus relieving pressure on pinched nerves. Medications such as NSAIDS
and other anti-inflammatory medications are often used to alleviate pain, although they are not typically effective at addressing the cause of the pain. Surgical treatments are more aggressive than medication or physical therapy, but in appropriate cases surgery may be the best way to achieve a lessening of the syniptoms associated with LSS.
The most common surgery for treating LSS is deconipresive laminectomy, in which the lainina of one or more vertebrae is removed to create more space for the nerves.
The intervertebral disc may also be removed, and the vertebrae may be fused to strengthen unstable segments. The success rate of decoinpressive laminectoiny has been reported to be in excess of 65%, with a significant reduction in LSS symptoms being achieved in many cases.
More recently, a second surgical technique has been developed in which the vertebrae are distracted and an interspinous spacer is implanted to maintain the desired separation between the segments. This technique is somewhat less invasive than decompressive laminectomy, but may provide significant benefits to patients experiencing LSS symptoms.
As with otlier surgeries, one consideration when performing surgery to implant an interspinous spacer is the size of the incision that is required to allow introduction of the device. Minimally invasive techniques are generally preferred, but the interspinous spacers previously known to the art did not work well with minimally invasive surgical techniques. The implantation profile presented by known spacers precludes introduction tlzrough a very small incision.
A need therefore exists for an interspinous spacer that can be implanted using minimally invasive surgical techniques. The present invention addresses that need.
SUMMARY OF THE INVENTION
Briefly describing one aspect of the present invention, there is provided an interspinous spacer that is configurable to a first, collapsed configuration, and a second, expanded configuration. The spacer may be implanted in a minimally invasive manner due to the reduced profile of the collapsed configuration of the spacer.
The present invention also provides a method of introducing an interspinous spacer between adjacent spinous processes. The nlethod preferably comprises: (a) providing a spacer that is configurable to a collapsed configuration and to an expanded configuration;
wherein said collapsed configuration presents an iinplantation profile that is at least 10%
FIELD OF THE INVENTION
The present invention relates generally to devices for treating spinal stenosis, and more particularly to interspinous spacers that can be implanted in a minimally invasive manner to treat spinal stenosis.
BACKGROUND OF THE INVENTION
Lumbar spinal stenosis ("LSS", and sometimes called sciatica) is a condition of the spine characterized by a narrowing of the lumbar spinal canal. With spinal stenosis, the spinal canal narrows and pinches the spinal cord and nerves, causing pain in the back and legs. It is estimated that approximately 5 in 10,000 people develop LSS each year. For patients who seek the aid of a physician specialist for back pain, approximately 12-15%
are diagnosed as having LSS.
Several causes of spinal stenosis have been identified, including aging, heredity, arthritis, and changes in blood flow to the lower spine. Aging is believed to be the most common cause, because as a person ages the ligaments coimecting the bones of the spine can thicken and spurs may develop on the bones and into the spinal canal. The cushioning discs between the vertebrae also frequently deteriorate, and the facet joints may begin to break down. Heredity is believed to play a role in some cases because it may cause some people to have a smaller than average spinal canal, typically leading to LSS
symptoms even at a relatively young age.
The most common symptoms of spinal stenosis is pain and difficulty when walking, although nunibness, tingling, hot or cold feelings in the legs, and wealaiess or tiredness may also be experienced. In extreme cases spinal stenosis can cause cauda equina syndrome, a syndrome characterized by neuromuscular dysfunction that may result in permanent i}erve dainage.
Common treatinents for LSS include pliysical therapy (including changes in posture), medication, and occasionally surgeiy. Changes in posture and physical tlierapy may be effective in flexing the spine to enlarge the space available to the spinal cord and nerves - thus relieving pressure on pinched nerves. Medications such as NSAIDS
and other anti-inflammatory medications are often used to alleviate pain, although they are not typically effective at addressing the cause of the pain. Surgical treatments are more aggressive than medication or physical therapy, but in appropriate cases surgery may be the best way to achieve a lessening of the syniptoms associated with LSS.
The most common surgery for treating LSS is deconipresive laminectomy, in which the lainina of one or more vertebrae is removed to create more space for the nerves.
The intervertebral disc may also be removed, and the vertebrae may be fused to strengthen unstable segments. The success rate of decoinpressive laminectoiny has been reported to be in excess of 65%, with a significant reduction in LSS symptoms being achieved in many cases.
More recently, a second surgical technique has been developed in which the vertebrae are distracted and an interspinous spacer is implanted to maintain the desired separation between the segments. This technique is somewhat less invasive than decompressive laminectomy, but may provide significant benefits to patients experiencing LSS symptoms.
As with otlier surgeries, one consideration when performing surgery to implant an interspinous spacer is the size of the incision that is required to allow introduction of the device. Minimally invasive techniques are generally preferred, but the interspinous spacers previously known to the art did not work well with minimally invasive surgical techniques. The implantation profile presented by known spacers precludes introduction tlzrough a very small incision.
A need therefore exists for an interspinous spacer that can be implanted using minimally invasive surgical techniques. The present invention addresses that need.
SUMMARY OF THE INVENTION
Briefly describing one aspect of the present invention, there is provided an interspinous spacer that is configurable to a first, collapsed configuration, and a second, expanded configuration. The spacer may be implanted in a minimally invasive manner due to the reduced profile of the collapsed configuration of the spacer.
The present invention also provides a method of introducing an interspinous spacer between adjacent spinous processes. The nlethod preferably comprises: (a) providing a spacer that is configurable to a collapsed configuration and to an expanded configuration;
wherein said collapsed configuration presents an iinplantation profile that is at least 10%
smaller than the corresponding profile when the spacer is in its expanded configuration;
(b) causing said spacer to assume its collapsed configuration; (c) introducing said spacer into a medical patient while the spacer is in its collapsed configuration; and (d) allowing the spacer to assume its expanded configuration while in the medical patient.
At the conclusion of the method the expanded-configuration spacer is positioned between adjacent spinous processes.
In one aspect of the invention the spacer comprises a blocking member and four arms extending therefrom. Accordingly, the spacer may have an "H"-shaped configuration when in a relaxed configuration, and an "I"-shaped configuration when in a collapsed configuration. The method of implanting such a spacer may comprise:
(a) collapsing the spacer to its "I"-shaped configuration; (b) putting the collapsed spacer in a caimula to facilitate iinplantation in a medical patient; (c) from an oblique posterior approach positioning the distal end of the cannula in a medical patient so that the end of the caimula clears each of a pair of adjacent spinal processes; (d) pushing the collapsed spacer through the caimula until two of the arms exit the caimula and position themselves longitudinally beside the adjacent spinal processes; and (f) withdrawing said cannula while allowing or causing the spacer to continue through the cannula such that the spacer exits the cannula and the remaining two arms are positioned longitudinally on the other side of the adjacent spinal processes.
Objects and advantages of these and otlier aspects of the claimed invention will be apparent from the following description.
BRIEF DESCRIPTION OF THE DRAWINGS
FIGS. lA-1C show an interspinous spacer according to one preferred einbodiinent of the present invention.
FIGS. 2A-2E show the interspinous spacer of FIG.1 Ueing implanted in a medical patient.
FIGS. 3A-3C show an interspinous spacer according to another preferred emUodiinent of the present invention.
FIGS. 4A-4D show an interspinous spacer according to another preferred einbodiment of the present invention.
FIG. 5 shows an interspinous spacer according to another preferred einUodiment of the present invention, including a rigid spacer portion to give the device an adjustable height.
(b) causing said spacer to assume its collapsed configuration; (c) introducing said spacer into a medical patient while the spacer is in its collapsed configuration; and (d) allowing the spacer to assume its expanded configuration while in the medical patient.
At the conclusion of the method the expanded-configuration spacer is positioned between adjacent spinous processes.
In one aspect of the invention the spacer comprises a blocking member and four arms extending therefrom. Accordingly, the spacer may have an "H"-shaped configuration when in a relaxed configuration, and an "I"-shaped configuration when in a collapsed configuration. The method of implanting such a spacer may comprise:
(a) collapsing the spacer to its "I"-shaped configuration; (b) putting the collapsed spacer in a caimula to facilitate iinplantation in a medical patient; (c) from an oblique posterior approach positioning the distal end of the cannula in a medical patient so that the end of the caimula clears each of a pair of adjacent spinal processes; (d) pushing the collapsed spacer through the caimula until two of the arms exit the caimula and position themselves longitudinally beside the adjacent spinal processes; and (f) withdrawing said cannula while allowing or causing the spacer to continue through the cannula such that the spacer exits the cannula and the remaining two arms are positioned longitudinally on the other side of the adjacent spinal processes.
Objects and advantages of these and otlier aspects of the claimed invention will be apparent from the following description.
BRIEF DESCRIPTION OF THE DRAWINGS
FIGS. lA-1C show an interspinous spacer according to one preferred einbodiinent of the present invention.
FIGS. 2A-2E show the interspinous spacer of FIG.1 Ueing implanted in a medical patient.
FIGS. 3A-3C show an interspinous spacer according to another preferred emUodiinent of the present invention.
FIGS. 4A-4D show an interspinous spacer according to another preferred einbodiment of the present invention.
FIG. 5 shows an interspinous spacer according to another preferred einUodiment of the present invention, including a rigid spacer portion to give the device an adjustable height.
FIG. 6 shows an interspinous spacer implanted in a medical patient.
FIGS. 7A-7L show alternative shapes of an interspinous spacer according to other preferred embodiunents of the present invention.
FIGS. 8A-8M show representative configurations of an interspinous spacer according to other preferred embodiments of the present invention.
FIGS. 9A-9B show the use of a spacer/stabilizer, according to one preferred embodiment of the present invention.
FIGS. IOA-10K show alternative spacers/stabilizers, according to other prefeired embodiments of the present invention.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
For the purposes of promoting an understanding of the principles of the invention, reference will now be made to certain preferred embodiments and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the invention is thereby intended, such alterations and further modifications in the preferred embodiinents being contemplated as would normally occur to one skilled in the art to which the iiivention relates.
As indicated above, one aspect of the present invention relates to a method of providing an interspinous spacer between adjacent spinous processes. The method may be accomplished by: (a) providing a spacer that is configurable to a collapsed configuration and to an expanded configuration; wherein the collapsed configuration presents an implantation profile that is at least 10% smaller than the corresponding profile when the spacer is in its expanded configuration; (b) causing the spacer to assume its collapsed configuration; (c) introducing the spacer into a medical patient while the spacer is in its collapsed configuration; and (d) allowing the spacer to assuine its expanded configuration while in the medical patient. At the conclusion of the method the expanded-configuration spacer is positioned between adjacent spinous processes.
As to the characteristics of the spacer generally, the spacer is designed to maintain a minimal distance between the spinous processes of adjacent vertebrae. As such, the spacer typically has a blocking portion that keeps the vertebrae from coming together. In general, the blocking portion maintains a distance of 1/4" to '/z" between the spinous processes.
Additionally, the spacer is preferably designed to fit snugly around the spinous processes, and thus to avoid being dislodged by movement of the spine. In one einbodiment the spacer accomplishes that end by including "arms" extending fioin the blocking portion upward along both sides of the upper spinous process, and "anns"
FIGS. 7A-7L show alternative shapes of an interspinous spacer according to other preferred embodiunents of the present invention.
FIGS. 8A-8M show representative configurations of an interspinous spacer according to other preferred embodiments of the present invention.
FIGS. 9A-9B show the use of a spacer/stabilizer, according to one preferred embodiment of the present invention.
FIGS. IOA-10K show alternative spacers/stabilizers, according to other prefeired embodiments of the present invention.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
For the purposes of promoting an understanding of the principles of the invention, reference will now be made to certain preferred embodiments and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the invention is thereby intended, such alterations and further modifications in the preferred embodiinents being contemplated as would normally occur to one skilled in the art to which the iiivention relates.
As indicated above, one aspect of the present invention relates to a method of providing an interspinous spacer between adjacent spinous processes. The method may be accomplished by: (a) providing a spacer that is configurable to a collapsed configuration and to an expanded configuration; wherein the collapsed configuration presents an implantation profile that is at least 10% smaller than the corresponding profile when the spacer is in its expanded configuration; (b) causing the spacer to assume its collapsed configuration; (c) introducing the spacer into a medical patient while the spacer is in its collapsed configuration; and (d) allowing the spacer to assuine its expanded configuration while in the medical patient. At the conclusion of the method the expanded-configuration spacer is positioned between adjacent spinous processes.
As to the characteristics of the spacer generally, the spacer is designed to maintain a minimal distance between the spinous processes of adjacent vertebrae. As such, the spacer typically has a blocking portion that keeps the vertebrae from coming together. In general, the blocking portion maintains a distance of 1/4" to '/z" between the spinous processes.
Additionally, the spacer is preferably designed to fit snugly around the spinous processes, and thus to avoid being dislodged by movement of the spine. In one einbodiment the spacer accomplishes that end by including "arms" extending fioin the blocking portion upward along both sides of the upper spinous process, and "anns"
5 extending from the blocldng portion downward along both sides of the lower spinous process. The arms keep the spacer from moving laterally with respect to the spinous processes. In some einbodiments the arms have a relaxed configuration such that the distance between opposing anns is slightly less than width of a spinous process at that point. Tlius, the arms will grip the spinous process to provide additional stability to the implanted spacer.
In one aspect of the invention the spacer comprises a blocking member with four anns extending therefrom. Accordingly, the spacer may have an "H"-shaped configuration when in a relaxed configuration, and an "I"-shaped configuration when in a collapsed configuration. The method of implanting such a spacer may comprise:
(a) collapsing the spacer to its "I"-shaped configuration; (b) putting the collapsed spacer in a camlula to facilitate implantation in a medical patient; (c) from an oblique posterior approach positioning the distal end of the cannula in a medical patient so that the end of the cannula clears each of a pair of adjacent spinal processes; (d) pushing the collapsed spacer through the cannula until two of the arms exit the cannula and position themselves longitudinally beside the adjacent spinal processes; and (f) withdrawing said cannula wliile allowing or causing the spacer to continue through the cannula such that the spacer exits the caimula and the renlaining two arms are positioned longitudinally on the otlier side of the adjacent spinal processes.
In one embodiment the spacer is collapsible by virtue of the fact that the material used to malce the spacer is very elastic and pliable. In such embodiments the spacer arms may be manipulated so as to transform the H-shaped configuration to an I-shaped configuration merely by bending the arms from an orientation that is generally perpendicular to the crossbar of the "H" to an orientation that is generally parallel to the crossbar of the "H." Accordingly, in one embodiment the H-shaped iniplant is converted to an I-shaped implant by folding the upwardly and downwardly extending anns so that they extend horizontally, i.e., the folded arms extend in a direction that is generally parallel to the crossbar of the "H." When the force manipulating the spacer arms is released, the arms then return to their original orientation that is generally perpendicular to the crossbar of the "H." FIGS. lA-1C, described below, show the manipulation of one H-shaped embodiment.
In another embodiment the spacer is collapsible by virtue of a pivot point near the center of the spacer. Such einbodiments may work much like a pair of scissors, with four artns extending from a ceiitral pivot. As with scissors, the device may be converted from a generally "X"-shaped device to a generally "I"-shaped device by pivoting one pair of anus relative to the other. FIGS. 4A-4C, described below, show one such pivoting einbodiinent.
The ability of the spacer to assume a collapsed configuration allows the spacer to be in'lplanted using a minimally invasive surgical technique. Most preferably, the surgery is accomplished using a posterior oblique approach through a small incision in the patient's back.
Regardless of the surgical approach used for implantation, when the spacer passes into the body it presents an "implantation profile" corresponding to the size of the implant as it passes through the plane of the opening in the body. The implantation profile therefore defines the size of the opening required to accept the implant.
While it is appreciated that different surgeons may use different orientations of a spacer wlien implanting it into a patient, there is generally one orientation that presents a smaller implantation profile than the others. For the puiposes of this disclosure then, the tenn iinplantation profile is used to identify the size of an implant as it passes through an opening in the body, given that the inlplant is manipulated so as to present the smallest possible implantation profile. To the extent the size of the portion of the implant that is passing through the opening increases or decreases as different portions of the iinplant pass througli the opening, the iinplantation profile is the maximum size presented to the opening during iinplantation, and tlierefore corresponds to the ininimum opening size required to accommodate the implant.
In one embodiment of the present invention the implantation profile is at least about 10% smaller than the corresponding profile wlien the spacer is in its expanded configuration. In other embodinlents the iinplantation profile is at least about 20% sinaller than the corresponding profile when the spacer is in its expanded configuration. More preferably, the implantation profile is about 25% smaller than the corresponding profile when the spacer is in its expanded configuration. Most preferably, the implantation profile is at least 50% smaller than the corresponding profile when the spacer is in its expanded configuration.
An interspinous spacer for use in the invention may be formed froin a wide variety of biocompatible materials that can undergo reversible elastic deformation.
Examples of such materials include elastic or rubbery polymers, hydrogels or other hydrophilic polymers, or coinposites thereof. Particularly suitable elastomers include silicone, polyurethane, copolymers of silicone and polyurethane, polyolefins, such as polyisobutylene and polyisoprene, neoprene, nitrile, vulcanized rubber and combinations thereof.
Examples of polyurethanes include thennoplastic polyurethanes, aliphatic polyurethanes, segmented polyurethanes, hydrophilic polyurethanes, polyether-urethane, polycarbonate-urethane and silicone polyetheruretliane. Other suitable hydrophilic polyzners include polyvinyl alcohol hydrogel, polyacrylamide hydrogel, polyacrylic hydrogel, poly(N-vinyl-2-pyrrolidone hydrogel, polyhydroxyethyl methacrylate hydrogel, and naturally occurring materials such as collagen and polysaccharides, such as hyaluronic acid and cross-linked carboxyl-containing polysaccharides, and combinations thereof.
In other embodiments the spacer is made of a metal that can undergo reversible elastic deformation, such as shape memory metals or nickel titanium.
The nature of the materials employed to form the blocking portion of the spacer should be selected so the formed implants have sufficient load bearing capacity. In preferred embodiments, a compressive modulus of at least about 0.1 Mpa is desired, although compressive strengths in the range of about 1 Mpa to about 20 Mpa are more preferred. Most preferably the compressive modulus is at least about 5 Mpa.
In some embodiments the spacer may also advantageously deliver desired phai7nacological agents. The pharmacological agent may be a growtll factor that may advantageously repair dainaged tissue or bone, and may include an osteoinductive factor (e.g., a bone morphogenetic protein), transfonning growth factor-ss (TGF-ss), insulin-like growth factor, platelet derived growth factor, fibroblast growth factor or otlier similar growth factor or coinbination thereof having the ability to repair tissue or bone.
In otlier fonns of the invention, the spacer may comprise a phamlacological agent used for treating various spinal conditions, including degenerative disc disease, spinal arthritis, spinal infection, spinal tumor and osteoporosis. Such agents include antibiotics, analgesics, anti-inflammatory drugs, including steroids, and conibinations thereof. Other such agents are well known to the skilled artisan. These agents are also used in therapeutically effective amounts. Such amounts may be determined by the skilled artisan depending on the specific case.
The pharinacological agents, if any, are preferably dispersed within the spacer for in vivo release. The phannacological agents may be dispersed in the spacer by adding the agents to the spacer when it is formed, by soaking a fonned spacer in an appropriate solution containing the agent, or by other appropriate methods known to the skilled artisan. In other forms of the invention, the phamiacological agents may be chemically or otherwise associated with the spacer. For example, the agents may be chemically attached to the outer surface of the spacer.
In some embodiments the device may include one of more X-ray markers such as tantalum marlcers to assist in positioning the implant. A combination of larger x-ray inarlcers and smaller x-ray markers may be used to facilitate observing the orientation of the device when implanted. The x-ray markers can be more readily observed on x-rays, making the positioning and orientation of the device more easily observed and corrected.
Referring now to the drawings, FIGS. 1A-C show an interspinous spacer according to one embodiment of the present invention. Spacer 10 includes a blocking member 15 and arms 11, 12, 13, and 14. When the spacer is in its relaxed (expanded) configuration as shown in FIG. 1A, it resembles an "H," with arms 11, 12, 13, and 14 being the legs of the H, and blocking meinber 15 being the crossbar. As illustrated in the drawing, the anns are generally perpendicular to the blocking member when the spacer is in its relaxed/expanded configuration.
To use the spacer, the anns are manipulated to be parallel to the bloclcing niember, manipulating the spacer to its collapsed (implantable) configuration as illustrated in FIGS.
1B and 1C. The manipulation makes the spacer assume the shape of an "I" rather than the shape of ari "H." Arrows a, b, c, and d, show the direction of the manipulation to transform the "H" to an "I." As indicated above, the preferred manipulation converts the H-shaped implant to an I-shaped iinplant by folding the upwardly and dovcniwardly extending anns so that they extend horizontally in a direction that is generally parallel to the crossbar of the "H." When the spacer is manipulated to its collapsed/unplantable configuration, the implantation profile of the profile is reduced.
FIGS. 2A-E show one embodiment of a method for implanting the spacer. In FIG.
2A, spacer 10 is loaded in cannula 20 while the spacer is in its collapsed/implantable configuration. The spacer is in its collapsed configuration so that its iinplantation profile is reduced from the corresponding profile when the spacer is in its relaxed configuration.
Camiula 20 is positioned between two spinous processes, with the tip 20a of the carniula extending just beyond the spinous processes when the cannula is inserted from a posterior oblique approach. When the cannula is positioned, the spacer is pushed fioin the cannula so that the leading pair of arms 22 and 24 begins to unfold fiom its collapsed/implantable configuration to its relaxed/expanded configuratiori, as shown in FIG. 2B. As the arms unfold they extend upward and downward along one side of two spinous processes, as shown in FIG. 2C.
The cannula is then withdrawn as the spacer is ejected, as shown in FIGS. 2D.
The blocking portion 25 of spacer 10 is positioned between the two spinous processes, and the second pair of arms 21 and 23 unfolds to extend upward and downward along the second side of the spinous processes, as shown in FIG. 2E.
In another embodiment the spacer may have indents and/or otlZer surface features to facilitate collapsing and iniplanting the spacer, or to avoid craclcing or tearing the iinplant when the anns are folded to their collapsed configuration. Features such as ridges to facilitate gripping the spinous processes may also be included.
For example, FIGS. 7A through 7L show einbodiinents having surface features to reduce compressive forces on the outside walls during deformation (in the "I"
shape). The illustrated surface features, which are merely examples of the many types and/or shapes of surface features that may be utilized, act to reduce compressive forces on the outside surface of the iinplant when the iinplant is folded from its "H" configuration to its "I"
configuration.
In addition or as an alternative, surface features may be included on the "imzer"
surface of the iinplant to reduce tensile forces on those surfaces when the implant is defonned. FIGS. 8A tlirough 8M show some preferred embodiments of such surface features. Here too, the illustrated surface features are merely examples of the many types and/or shapes of surface features that may be utilized to reduce "stretcliing"
or tensile forces on the inside surface of the implant when the implant is folded from its "H"
configuration to its "I" configuration.
One einbodiment effective to reduce botli compressive and tensile forces is shown in FIGS. 3A-3C. In that embodiment, spacer 30 comprises arms 31, 32, 33, and 34, and 5 bloclcing portion 35. Blocking portion 35 includes at least one indent 35a, and may include two indents as shown in FIG. 3A. The implant is manipulated from its relaxed configuration to its straiglitened configuration as before. Arms 31 and 32 are folded downward until they are generally horizontal and lie in the same direction as blocking member 35. Arms 32 and 34 are folded upward until they are generally horizontal and lie 10 in the same direction as blocking meinber 35. The folded implant can then be placed in a cannula and pushed through a small opening in a patient's body as described above. Once implanted, the device relaxes to its H-shaped configuration with indents 35a centering the implant around the spinous processes and arms 31, 32, 33, and 34 preventing lateral displacement.
In another embodiment the implant may have one or more arms that pivot in relation to other non-pivoting anns. The arms preferable pivot around a central point in the blocking ineinber. Most preferably, the device comprises four arms arranged as two pivoting pairs, with each of the two pairs of arms pivoting together. In the most preferred embodiments, the pivoting arms are substantially rigid, although they may be elastic in other einbodiments.
FIG. 4A shows one preferred embodiment of the present invention in which the iinplant has pivoting arms. Pivot post 47 defines the point around which arms 41, 42, 43, and 44 pivot. In the illustrated embodiment, arms 41 and 42 form one pair, and arms 43 and 44 forin another pair. A spring 48 may be used to bias the arms to their closed position, as shown in FIGS. 4A and 4B. In some einbodiments spring 48 is wound at least partially around pivot post 47.
To operate implant 40, the iinplant is preferably allowed to adopt its closed position as shown in FIG. 4A. In this position the implant has its minimum implantation profile, allowing the closed iinplant to pass through a small incision in a patient. After the ilnplant has been introduced into the patient, the ilnplant is opened by allowing the anus to move in the direction of the arrows shown in FIG. 4C. This allows the implant to adopt its open configuration as shown in FIG. 4D. In that configuration, the iunplant has a profile that is larger than the profile of the implant in its closed configuration.
In some embodiments the blocking member portion of implant 40 has a concave shape wlien the arms are opened to their open configuration. This allows the blocking inember to fit more securely around the interspinous processes.
In another embodiment of the present invention the implant includes a spacer portion between the two pair of opposing arms. The spacer portion may give the device an adjustable height, with varying sizes of rigid spacer portions being available.
FIG. 5 shows one embodiment of the device of the present invention having a spacer/stabilizer portion. In spacer 50, arms 51, 52, 53, and 54 extend from bloclcing portion 55 and spacer/stabilizer portion 56.
The device with a spacer is used in a inanner siinilar to the device without a spacer.
Accordingly, arms 51, 52, 53, and 54 may fold down to lie horizontally along the axis of blocking member 55 and spacer portion 56, so that the device has an implantation profile that is at least 10% smaller than the corresponding profile of the device in its relaxed configuration.
Alternative embodiments of an interspinous spacer having a spacer/stabilizer are shown in FIGS. 9A-9B, and in FIGS. 10A-10K. These embodiments are particularly effective for reducing or preventing iyz vivo deformation of the device, and thus for reducing or preventing dislocation and/or migration after implantation. In the einbodiments illustrated in the drawings, the central shank 91 provides the spacing effect for varying desired thiclaiesses, while the end portions 92 and 93 provide stabilization against in vivo deformation into the "I" shape. As may be appreciated by persons skilled in the art, the illustrated spacers/stabilizers inay be incorporated into the implant in vivo, with the spacer/stabilizer being installed and assembled oi-Ay after the device has assumed its "H"
shape.
FIG. 6 shows an interspinous spacer according to one preferred embodiment of the present invention, after implantation in a medical patient. Arms 61, 62, 63, and 64 of spacer 60 grip the spiiious processes 66a and 66b to hold the spacer in position.
While the invention has been illustrated and described in detail in the drawings and foregoing description, the same is to be considered as illustrative and not restrictive in character, it being understood that only the preferred embodiinent has been shown and described and that all changes and modifications that come within the spirit of the invention are desired to be protected.
In one aspect of the invention the spacer comprises a blocking member with four anns extending therefrom. Accordingly, the spacer may have an "H"-shaped configuration when in a relaxed configuration, and an "I"-shaped configuration when in a collapsed configuration. The method of implanting such a spacer may comprise:
(a) collapsing the spacer to its "I"-shaped configuration; (b) putting the collapsed spacer in a camlula to facilitate implantation in a medical patient; (c) from an oblique posterior approach positioning the distal end of the cannula in a medical patient so that the end of the cannula clears each of a pair of adjacent spinal processes; (d) pushing the collapsed spacer through the cannula until two of the arms exit the cannula and position themselves longitudinally beside the adjacent spinal processes; and (f) withdrawing said cannula wliile allowing or causing the spacer to continue through the cannula such that the spacer exits the caimula and the renlaining two arms are positioned longitudinally on the otlier side of the adjacent spinal processes.
In one embodiment the spacer is collapsible by virtue of the fact that the material used to malce the spacer is very elastic and pliable. In such embodiments the spacer arms may be manipulated so as to transform the H-shaped configuration to an I-shaped configuration merely by bending the arms from an orientation that is generally perpendicular to the crossbar of the "H" to an orientation that is generally parallel to the crossbar of the "H." Accordingly, in one embodiment the H-shaped iniplant is converted to an I-shaped implant by folding the upwardly and downwardly extending anns so that they extend horizontally, i.e., the folded arms extend in a direction that is generally parallel to the crossbar of the "H." When the force manipulating the spacer arms is released, the arms then return to their original orientation that is generally perpendicular to the crossbar of the "H." FIGS. lA-1C, described below, show the manipulation of one H-shaped embodiment.
In another embodiment the spacer is collapsible by virtue of a pivot point near the center of the spacer. Such einbodiments may work much like a pair of scissors, with four artns extending from a ceiitral pivot. As with scissors, the device may be converted from a generally "X"-shaped device to a generally "I"-shaped device by pivoting one pair of anus relative to the other. FIGS. 4A-4C, described below, show one such pivoting einbodiinent.
The ability of the spacer to assume a collapsed configuration allows the spacer to be in'lplanted using a minimally invasive surgical technique. Most preferably, the surgery is accomplished using a posterior oblique approach through a small incision in the patient's back.
Regardless of the surgical approach used for implantation, when the spacer passes into the body it presents an "implantation profile" corresponding to the size of the implant as it passes through the plane of the opening in the body. The implantation profile therefore defines the size of the opening required to accept the implant.
While it is appreciated that different surgeons may use different orientations of a spacer wlien implanting it into a patient, there is generally one orientation that presents a smaller implantation profile than the others. For the puiposes of this disclosure then, the tenn iinplantation profile is used to identify the size of an implant as it passes through an opening in the body, given that the inlplant is manipulated so as to present the smallest possible implantation profile. To the extent the size of the portion of the implant that is passing through the opening increases or decreases as different portions of the iinplant pass througli the opening, the iinplantation profile is the maximum size presented to the opening during iinplantation, and tlierefore corresponds to the ininimum opening size required to accommodate the implant.
In one embodiment of the present invention the implantation profile is at least about 10% smaller than the corresponding profile wlien the spacer is in its expanded configuration. In other embodinlents the iinplantation profile is at least about 20% sinaller than the corresponding profile when the spacer is in its expanded configuration. More preferably, the implantation profile is about 25% smaller than the corresponding profile when the spacer is in its expanded configuration. Most preferably, the implantation profile is at least 50% smaller than the corresponding profile when the spacer is in its expanded configuration.
An interspinous spacer for use in the invention may be formed froin a wide variety of biocompatible materials that can undergo reversible elastic deformation.
Examples of such materials include elastic or rubbery polymers, hydrogels or other hydrophilic polymers, or coinposites thereof. Particularly suitable elastomers include silicone, polyurethane, copolymers of silicone and polyurethane, polyolefins, such as polyisobutylene and polyisoprene, neoprene, nitrile, vulcanized rubber and combinations thereof.
Examples of polyurethanes include thennoplastic polyurethanes, aliphatic polyurethanes, segmented polyurethanes, hydrophilic polyurethanes, polyether-urethane, polycarbonate-urethane and silicone polyetheruretliane. Other suitable hydrophilic polyzners include polyvinyl alcohol hydrogel, polyacrylamide hydrogel, polyacrylic hydrogel, poly(N-vinyl-2-pyrrolidone hydrogel, polyhydroxyethyl methacrylate hydrogel, and naturally occurring materials such as collagen and polysaccharides, such as hyaluronic acid and cross-linked carboxyl-containing polysaccharides, and combinations thereof.
In other embodiments the spacer is made of a metal that can undergo reversible elastic deformation, such as shape memory metals or nickel titanium.
The nature of the materials employed to form the blocking portion of the spacer should be selected so the formed implants have sufficient load bearing capacity. In preferred embodiments, a compressive modulus of at least about 0.1 Mpa is desired, although compressive strengths in the range of about 1 Mpa to about 20 Mpa are more preferred. Most preferably the compressive modulus is at least about 5 Mpa.
In some embodiments the spacer may also advantageously deliver desired phai7nacological agents. The pharmacological agent may be a growtll factor that may advantageously repair dainaged tissue or bone, and may include an osteoinductive factor (e.g., a bone morphogenetic protein), transfonning growth factor-ss (TGF-ss), insulin-like growth factor, platelet derived growth factor, fibroblast growth factor or otlier similar growth factor or coinbination thereof having the ability to repair tissue or bone.
In otlier fonns of the invention, the spacer may comprise a phamlacological agent used for treating various spinal conditions, including degenerative disc disease, spinal arthritis, spinal infection, spinal tumor and osteoporosis. Such agents include antibiotics, analgesics, anti-inflammatory drugs, including steroids, and conibinations thereof. Other such agents are well known to the skilled artisan. These agents are also used in therapeutically effective amounts. Such amounts may be determined by the skilled artisan depending on the specific case.
The pharinacological agents, if any, are preferably dispersed within the spacer for in vivo release. The phannacological agents may be dispersed in the spacer by adding the agents to the spacer when it is formed, by soaking a fonned spacer in an appropriate solution containing the agent, or by other appropriate methods known to the skilled artisan. In other forms of the invention, the phamiacological agents may be chemically or otherwise associated with the spacer. For example, the agents may be chemically attached to the outer surface of the spacer.
In some embodiments the device may include one of more X-ray markers such as tantalum marlcers to assist in positioning the implant. A combination of larger x-ray inarlcers and smaller x-ray markers may be used to facilitate observing the orientation of the device when implanted. The x-ray markers can be more readily observed on x-rays, making the positioning and orientation of the device more easily observed and corrected.
Referring now to the drawings, FIGS. 1A-C show an interspinous spacer according to one embodiment of the present invention. Spacer 10 includes a blocking member 15 and arms 11, 12, 13, and 14. When the spacer is in its relaxed (expanded) configuration as shown in FIG. 1A, it resembles an "H," with arms 11, 12, 13, and 14 being the legs of the H, and blocking meinber 15 being the crossbar. As illustrated in the drawing, the anns are generally perpendicular to the blocking member when the spacer is in its relaxed/expanded configuration.
To use the spacer, the anns are manipulated to be parallel to the bloclcing niember, manipulating the spacer to its collapsed (implantable) configuration as illustrated in FIGS.
1B and 1C. The manipulation makes the spacer assume the shape of an "I" rather than the shape of ari "H." Arrows a, b, c, and d, show the direction of the manipulation to transform the "H" to an "I." As indicated above, the preferred manipulation converts the H-shaped implant to an I-shaped iinplant by folding the upwardly and dovcniwardly extending anns so that they extend horizontally in a direction that is generally parallel to the crossbar of the "H." When the spacer is manipulated to its collapsed/unplantable configuration, the implantation profile of the profile is reduced.
FIGS. 2A-E show one embodiment of a method for implanting the spacer. In FIG.
2A, spacer 10 is loaded in cannula 20 while the spacer is in its collapsed/implantable configuration. The spacer is in its collapsed configuration so that its iinplantation profile is reduced from the corresponding profile when the spacer is in its relaxed configuration.
Camiula 20 is positioned between two spinous processes, with the tip 20a of the carniula extending just beyond the spinous processes when the cannula is inserted from a posterior oblique approach. When the cannula is positioned, the spacer is pushed fioin the cannula so that the leading pair of arms 22 and 24 begins to unfold fiom its collapsed/implantable configuration to its relaxed/expanded configuratiori, as shown in FIG. 2B. As the arms unfold they extend upward and downward along one side of two spinous processes, as shown in FIG. 2C.
The cannula is then withdrawn as the spacer is ejected, as shown in FIGS. 2D.
The blocking portion 25 of spacer 10 is positioned between the two spinous processes, and the second pair of arms 21 and 23 unfolds to extend upward and downward along the second side of the spinous processes, as shown in FIG. 2E.
In another embodiment the spacer may have indents and/or otlZer surface features to facilitate collapsing and iniplanting the spacer, or to avoid craclcing or tearing the iinplant when the anns are folded to their collapsed configuration. Features such as ridges to facilitate gripping the spinous processes may also be included.
For example, FIGS. 7A through 7L show einbodiinents having surface features to reduce compressive forces on the outside walls during deformation (in the "I"
shape). The illustrated surface features, which are merely examples of the many types and/or shapes of surface features that may be utilized, act to reduce compressive forces on the outside surface of the iinplant when the iinplant is folded from its "H" configuration to its "I"
configuration.
In addition or as an alternative, surface features may be included on the "imzer"
surface of the iinplant to reduce tensile forces on those surfaces when the implant is defonned. FIGS. 8A tlirough 8M show some preferred embodiments of such surface features. Here too, the illustrated surface features are merely examples of the many types and/or shapes of surface features that may be utilized to reduce "stretcliing"
or tensile forces on the inside surface of the implant when the implant is folded from its "H"
configuration to its "I" configuration.
One einbodiment effective to reduce botli compressive and tensile forces is shown in FIGS. 3A-3C. In that embodiment, spacer 30 comprises arms 31, 32, 33, and 34, and 5 bloclcing portion 35. Blocking portion 35 includes at least one indent 35a, and may include two indents as shown in FIG. 3A. The implant is manipulated from its relaxed configuration to its straiglitened configuration as before. Arms 31 and 32 are folded downward until they are generally horizontal and lie in the same direction as blocking member 35. Arms 32 and 34 are folded upward until they are generally horizontal and lie 10 in the same direction as blocking meinber 35. The folded implant can then be placed in a cannula and pushed through a small opening in a patient's body as described above. Once implanted, the device relaxes to its H-shaped configuration with indents 35a centering the implant around the spinous processes and arms 31, 32, 33, and 34 preventing lateral displacement.
In another embodiment the implant may have one or more arms that pivot in relation to other non-pivoting anns. The arms preferable pivot around a central point in the blocking ineinber. Most preferably, the device comprises four arms arranged as two pivoting pairs, with each of the two pairs of arms pivoting together. In the most preferred embodiments, the pivoting arms are substantially rigid, although they may be elastic in other einbodiments.
FIG. 4A shows one preferred embodiment of the present invention in which the iinplant has pivoting arms. Pivot post 47 defines the point around which arms 41, 42, 43, and 44 pivot. In the illustrated embodiment, arms 41 and 42 form one pair, and arms 43 and 44 forin another pair. A spring 48 may be used to bias the arms to their closed position, as shown in FIGS. 4A and 4B. In some einbodiments spring 48 is wound at least partially around pivot post 47.
To operate implant 40, the iinplant is preferably allowed to adopt its closed position as shown in FIG. 4A. In this position the implant has its minimum implantation profile, allowing the closed iinplant to pass through a small incision in a patient. After the ilnplant has been introduced into the patient, the ilnplant is opened by allowing the anus to move in the direction of the arrows shown in FIG. 4C. This allows the implant to adopt its open configuration as shown in FIG. 4D. In that configuration, the iunplant has a profile that is larger than the profile of the implant in its closed configuration.
In some embodiments the blocking member portion of implant 40 has a concave shape wlien the arms are opened to their open configuration. This allows the blocking inember to fit more securely around the interspinous processes.
In another embodiment of the present invention the implant includes a spacer portion between the two pair of opposing arms. The spacer portion may give the device an adjustable height, with varying sizes of rigid spacer portions being available.
FIG. 5 shows one embodiment of the device of the present invention having a spacer/stabilizer portion. In spacer 50, arms 51, 52, 53, and 54 extend from bloclcing portion 55 and spacer/stabilizer portion 56.
The device with a spacer is used in a inanner siinilar to the device without a spacer.
Accordingly, arms 51, 52, 53, and 54 may fold down to lie horizontally along the axis of blocking member 55 and spacer portion 56, so that the device has an implantation profile that is at least 10% smaller than the corresponding profile of the device in its relaxed configuration.
Alternative embodiments of an interspinous spacer having a spacer/stabilizer are shown in FIGS. 9A-9B, and in FIGS. 10A-10K. These embodiments are particularly effective for reducing or preventing iyz vivo deformation of the device, and thus for reducing or preventing dislocation and/or migration after implantation. In the einbodiments illustrated in the drawings, the central shank 91 provides the spacing effect for varying desired thiclaiesses, while the end portions 92 and 93 provide stabilization against in vivo deformation into the "I" shape. As may be appreciated by persons skilled in the art, the illustrated spacers/stabilizers inay be incorporated into the implant in vivo, with the spacer/stabilizer being installed and assembled oi-Ay after the device has assumed its "H"
shape.
FIG. 6 shows an interspinous spacer according to one preferred embodiment of the present invention, after implantation in a medical patient. Arms 61, 62, 63, and 64 of spacer 60 grip the spiiious processes 66a and 66b to hold the spacer in position.
While the invention has been illustrated and described in detail in the drawings and foregoing description, the same is to be considered as illustrative and not restrictive in character, it being understood that only the preferred embodiinent has been shown and described and that all changes and modifications that come within the spirit of the invention are desired to be protected.
Claims (62)
1. A method of providing an interspinous spacer between adjacent spinous processes; said method comprising:
a) providing a spacer that is configurable to a collapsed configuration and to an expanded configuration; wherein said collapsed configuration presents an implantation profile that is at least 10% smaller than the corresponding profile when the spacer is in its expanded configuration;
b) causing said spacer to assume its collapsed configuration;
c) introducing said spacer into a medical patient while the spacer is in its collapsed configuration; and d) allowing the spacer to assume its expanded configuration while in the medical patient;
wherein said expanded-configuration spacer is positioned between adjacent spinous processes.
a) providing a spacer that is configurable to a collapsed configuration and to an expanded configuration; wherein said collapsed configuration presents an implantation profile that is at least 10% smaller than the corresponding profile when the spacer is in its expanded configuration;
b) causing said spacer to assume its collapsed configuration;
c) introducing said spacer into a medical patient while the spacer is in its collapsed configuration; and d) allowing the spacer to assume its expanded configuration while in the medical patient;
wherein said expanded-configuration spacer is positioned between adjacent spinous processes.
2. The method of claim 1 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 25%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
3. The method of claim 1 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 50%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
4. The method of claim 1 wherein said spacer comprises an elastomeric material.
5. The method of claim 4 wherein said elastomeric material comprises a member selected from the group consisting of natural and synthetic rubbers.
6. The method of claim 5 wherein said natural or synthetic rubber comprises silicone, polyurethane, polyolefins, such as polyisobutylene and polyisoprene, neoprene, nitrile rubber, vulcanized rubber and copolymers and combinations thereof.
6. The method of claim 5 wherein said polyurethane comprises a member selected from the group consisting of thermoplastic polyurethanes, aliphatic polyurethanes, aromatic polyurethanes, segmented polyurethanes, hydrophilic polyurethanes, polyether-urethane, polycarbonate-urethanes, silicone polycarbonate polyurethanes, and silicone polyetherurethanes.
6. The method of claim 5 wherein said polyurethane comprises a member selected from the group consisting of thermoplastic polyurethanes, aliphatic polyurethanes, aromatic polyurethanes, segmented polyurethanes, hydrophilic polyurethanes, polyether-urethane, polycarbonate-urethanes, silicone polycarbonate polyurethanes, and silicone polyetherurethanes.
7. The method of claim 4 wherein said elastomeric material comprises a member selected from the group consisting of polyvinyl alcohol hydrogel, polyacrylamide hydrogel, polyacrylic hydrogel, poly(N-vinyl-2-pyrrolidone hydrogel, polyhydroxyethyl methacrylate hydrogel, collagen, and polysaccharides, and combinations thereof.
8. The method of claim 1 wherein said spacer comprises a metal that can undergo reversible elastic deformation.
9. The method of claim 8 wherein said metal is a shape memory metal or nickel titanium.
10. The method of claim 1 wherein said spacer has a compressive modulus of at least about 1 Mpa.
11. The method of claim 10 wherein said spacer has a compressive modulus of at least about 5 Mpa.
12. The method of claim 1 wherein said spacer additionally comprises a pharmacological agent.
13. The method of claim 1 wherein said pharmacological agent comprises a member selected from the group consisting of antibiotics, analgesics, anti-inflammatory drugs, including steroids, and combinations thereof.
14. The method of claim 1 wherein said spacer additionally comprises one or more, x-ray markers.
15. The method of claim 1 wherein said spacer additionally includes a spacer/stabilizer portion.
16. A method of providing an interspinous spacer between adjacent spinous processes; said method comprising:
a) providing a spacer comprising a blocking member with arms extending therefrom; said spacer being configurable in a collapsed configuration and in a relaxed configuration; wherein said collapsed configuration presents an implantation profile that is at least 10% smaller than the corresponding profile when the spacer is in its relaxed configuration to facilitate minimally invasive implantation of the spacer;
b) collapsing said spacer to its collapsed configuration, said collapsed configuration having a reduced profile when compared to the relaxed configuration;
c) introducing said spacer into a medical patient while the spacer is in its collapsed configuration; and d) allowing the spacer to assume its relaxed configuration while in the patient;
wherein said spacer is implanted such that the blocking member is positioned between the spinous processes and each arm is positioned longitudinally on one side of a spinous process.
a) providing a spacer comprising a blocking member with arms extending therefrom; said spacer being configurable in a collapsed configuration and in a relaxed configuration; wherein said collapsed configuration presents an implantation profile that is at least 10% smaller than the corresponding profile when the spacer is in its relaxed configuration to facilitate minimally invasive implantation of the spacer;
b) collapsing said spacer to its collapsed configuration, said collapsed configuration having a reduced profile when compared to the relaxed configuration;
c) introducing said spacer into a medical patient while the spacer is in its collapsed configuration; and d) allowing the spacer to assume its relaxed configuration while in the patient;
wherein said spacer is implanted such that the blocking member is positioned between the spinous processes and each arm is positioned longitudinally on one side of a spinous process.
17. The method of claim 16 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 25%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
18. The method of claim 16 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 50%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
19. The method of claim 16 wherein said spacer comprises an elastomeric material.
20. The method of claim 19 wherein said elastomeric material comprises a member selected from the group consisting of silicone, polyurethane, copolymers of silicone and polyurethane, polyolefins, such as polyisobutylene and polyisoprene, neoprene, nitrile, vulcanized rubber and combinations thereof.
21. The method of claim 20 wherein said polyurethane comprises a member selected from the group consisting of thermoplastic polyurethanes, aliphatic polyurethanes, segmented polyurethanes, hydrophilic polyurethanes, polyether-urethane, polycarbonate-urethanes, and silicone polyetherurethanes.
22. The method of claim 19 wherein said elastomeric material comprises a member selected from the group consisting of polyvinyl alcohol hydrogel, polyacrylamide hydrogel, polyacrylic hydrogel, poly(N-vinyl-2-pyrrolidone hydrogel, polyhydroxyethyl methacrylate hydrogel, collagen, and polysaccharides, and combinations thereof.
23. The method of claim 16 wherein said spacer comprises a metal that can undergo reversible elastic deformation.
24. The method of claim 23 wherein said metal is a shape memory metal or nickel titanium.
25. The method of claim 16 wherein said spacer has a compressive modulus of at least about 1 Mpa.
26. The method of claim 25 wherein said spacer has a compressive modulus of at least about 5 Mpa.
27. The method of claim 16 wherein said spacer additionally comprises a pharmacological agent.
29. The method of claim 28 wherein said pharmacological agent comprises at least one growth factor.
29. The method of claim 28 wherein said pharmacological agent comprises at least one growth factor.
28. The method of claim 16 wherein said pharmacological agent comprises a member selected from the group consisting of antibiotics, analgesics, anti-inflammatory drugs, including steroids, and combinations thereof.
29. The method of claim 16 wherein said spacer additionally comprises one or more x-ray markers.
30. The method of claim 16 wherein said spacer additionally includes a spacer/stabilizer portion.
31. A method of implanting an interspinous spacer, said method comprising:
a) providing a spacer comprising a blocking member and four arms extending therefrom; said spacer having an "H"-shaped configuration when in a relaxed configuration; and an "I"-shaped configuration when in a collapsed configuration;
b) collapsing said spacer to its "I"-shaped configuration;
c) providing said collapsed spacer in a device for holding said spacer in its collapsed configuration to facilitate implantation in a medical patient, said cannula having a proximal end and a distal end;
d) positioning the distal end of said cannula in a medical patient so that the end of the cannula clears each of a pair of adjacent spinal processes;
e) pushing the collapsed spacer through the cannula until two of the arms exit the cannula and position themselves longitudinally beside the adjacent spinal processes;
f) withdrawing said cannula while allowing or causing the spacer to continue through the cannula such that the spacer exits the cannula and the remaining two arms are positioned longitudinally on the other side of the adjacent spinal processes.
a) providing a spacer comprising a blocking member and four arms extending therefrom; said spacer having an "H"-shaped configuration when in a relaxed configuration; and an "I"-shaped configuration when in a collapsed configuration;
b) collapsing said spacer to its "I"-shaped configuration;
c) providing said collapsed spacer in a device for holding said spacer in its collapsed configuration to facilitate implantation in a medical patient, said cannula having a proximal end and a distal end;
d) positioning the distal end of said cannula in a medical patient so that the end of the cannula clears each of a pair of adjacent spinal processes;
e) pushing the collapsed spacer through the cannula until two of the arms exit the cannula and position themselves longitudinally beside the adjacent spinal processes;
f) withdrawing said cannula while allowing or causing the spacer to continue through the cannula such that the spacer exits the cannula and the remaining two arms are positioned longitudinally on the other side of the adjacent spinal processes.
32 The method of claim 31 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 25%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
33 The method of claim 31 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 50%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
34 The method of claim 31 wherein said spacer comprises an elastomeric material
35 The method of claim 34 wherein said elastomeric material comprises a member selected from the group consisting of silicone, polyurethane, copolymers of silicone and polyurethane, polyolefins, such as polyisobutylene and polyisoprene, neoprene, nitrile, vulcanized rubber and combinations thereof.
36 The method of claim 35 wherein said polyurethane comprises a member selected from the group consisting of thermoplastic polyurethanes, aliphatic polyurethanes, segmented polyurethanes, hydrophilic polyurethanes, polyether-urethane, polycarbonate-urethanes, and silicone polyetherurethanes
37 The method of claim 34 wherein said elastomeric material comprises a member selected from the group consisting of polyvinyl alcohol hydrogel, polyacrylamide, hydrogel, polyacrylic hydrogel, poly(N-vinyl-2-pyrrolidone hydrogel, polyhydroxyethyl methacrylate hydrogel, collagen, and polysaccharides, and combinations thereof
38 The method of claim 31 wherein said spacer comprises a metal that can undergo reversible elastic deformation.
39 The method of claim 38 wherein said metal is a shape memory metal or nickel titanium
40 The method of claim 31 wherein said spacer has a compressive modulus of at least about 1 Mpa.
41 The method of claim 40 wherein said spacer has a compressive modulus of at least about 5 Mpa.
42 The method of claim 31 wherein said spacer additionally comprises a pharmacological agent.
43. The method of claim 31 wherein said pharmacological agent comprises a member selected from the group consisting of antibiotics, analgesics, anti-inflammatory drugs, including steroids, and combinations thereof.
44. The method of claim 31 wherein said spacer additionally comprises one or more x-ray markers.
45. The method of claim 31 wherein said spacer additionally includes a spacer/stabilizer portion.
46. A spacer for maintaining separation between adjacent spinous processes;
said spacer comprising a blocking member with arms extending therefrom;
wherein said spacer is configurable into a collapsed configuration and an expanded configuration; and further wherein said collapsed configuration presents a smaller profile than said expanded configuration to facilitate minimally invasive implantation of the spacer.
said spacer comprising a blocking member with arms extending therefrom;
wherein said spacer is configurable into a collapsed configuration and an expanded configuration; and further wherein said collapsed configuration presents a smaller profile than said expanded configuration to facilitate minimally invasive implantation of the spacer.
47. The spacer of claim 46 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 25%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
48. The spacer of claim 46 wherein said spacer is configurable to a collapsed configuration that presents an implantation profile that is at least 50%
smaller than the corresponding profile when the spacer is in its expanded configuration.
smaller than the corresponding profile when the spacer is in its expanded configuration.
49. The spacer of claim 46 wherein said spacer comprises an elastomeric material.
50. The spacer of claim 49 wherein said elastomeric material comprises a member selected from the group consisting of silicone, polyurethane, copolymers of silicone and polyurethane, polyolefins, such as polyisobutylene and polyisoprene, neoprene, nitrile, vulcanized rubber and combinations thereof.
51. The spacer of claim 50 wherein said polyurethane comprises a member selected from the group consisting of thermoplastic polyurethanes, aliphatic polyurethanes, segmented polyurethanes, hydrophilic polyurethanes, polyether-urethane, polycarbonate-urethanes, and silicone polyetherurethanes.
52. The spacer of claim 49 wherein said elastomeric material comprises a member selected from the group consisting of polyvinyl alcohol hydrogel, polyacrylamide hydrogel, polyacrylic hydrogel, poly(N-vinyl-2-pyrrolidone hydrogel, polyhydroxyethyl methacrylate hydrogel, collagen, and polysaccharides, and combinations thereof.
53. The spacer of claim 46 wherein said spacer comprises a metal that can undergo reversible elastic deformation.
54. The spacer of claim 53 wherein said metal is a shape memory metal or nickel titanium.
55. The spacer of claim 46 wherein said spacer has a compressive modulus of at least about 1 Mpa.
56. The spacer of claim 55 wherein said spacer has a compressive modulus of at least about 5 Mpa.
57. The spacer of claim 45 wherein said spacer additionally comprises a pharmacological agent.
58. The spacer of claim 46 wherein said pharmacological agent comprises a member selected from the group consisting of antibiotics, analgesics, anti-inflammatory drugs, including steroids, and combinations thereof.
59. The spacer of claim 46 wherein said spacer additionally comprises one or more x-ray markers.
60. The spacer of claim 46 wherein said spacer additionally includes a spacer/stabilizer portion.
61. The spacer of claim 46 wherein said spacer additionally comprises one or more surface features to reduce compressive forces on an outside wall during deformation.
62. The spacer of claim 46 wherein said spacer additionally comprises one or more surface features to reduce tensile forces on an inner surface of the implant when the implant is deformed.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/851,889 US7585316B2 (en) | 2004-05-21 | 2004-05-21 | Interspinous spacer |
US10/851,889 | 2004-05-21 | ||
PCT/US2005/015582 WO2005115261A1 (en) | 2004-05-21 | 2005-05-04 | Interspinous spacer |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2567403A1 true CA2567403A1 (en) | 2005-12-08 |
Family
ID=34968720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002567403A Abandoned CA2567403A1 (en) | 2004-05-21 | 2005-05-04 | Interspinous spacer |
Country Status (7)
Country | Link |
---|---|
US (2) | US7585316B2 (en) |
EP (1) | EP1765205B1 (en) |
JP (2) | JP4495218B2 (en) |
CN (1) | CN1997320B (en) |
AU (1) | AU2005247335C1 (en) |
CA (1) | CA2567403A1 (en) |
WO (1) | WO2005115261A1 (en) |
Families Citing this family (285)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8128661B2 (en) | 1997-01-02 | 2012-03-06 | Kyphon Sarl | Interspinous process distraction system and method with positionable wing and method |
US20080086212A1 (en) | 1997-01-02 | 2008-04-10 | St. Francis Medical Technologies, Inc. | Spine distraction implant |
US20080071378A1 (en) * | 1997-01-02 | 2008-03-20 | Zucherman James F | Spine distraction implant and method |
US6068630A (en) | 1997-01-02 | 2000-05-30 | St. Francis Medical Technologies, Inc. | Spine distraction implant |
US20080039859A1 (en) | 1997-01-02 | 2008-02-14 | Zucherman James F | Spine distraction implant and method |
US7959652B2 (en) * | 2005-04-18 | 2011-06-14 | Kyphon Sarl | Interspinous process implant having deployable wings and method of implantation |
US7306628B2 (en) | 2002-10-29 | 2007-12-11 | St. Francis Medical Technologies | Interspinous process apparatus and method with a selectably expandable spacer |
US7201751B2 (en) | 1997-01-02 | 2007-04-10 | St. Francis Medical Technologies, Inc. | Supplemental spine fixation device |
FR2844179B1 (en) * | 2002-09-10 | 2004-12-03 | Jean Taylor | POSTERIOR VERTEBRAL SUPPORT KIT |
US20080021468A1 (en) | 2002-10-29 | 2008-01-24 | Zucherman James F | Interspinous process implants and methods of use |
US7909853B2 (en) | 2004-09-23 | 2011-03-22 | Kyphon Sarl | Interspinous process implant including a binder and method of implantation |
US8147548B2 (en) | 2005-03-21 | 2012-04-03 | Kyphon Sarl | Interspinous process implant having a thread-shaped wing and method of implantation |
US8048117B2 (en) | 2003-05-22 | 2011-11-01 | Kyphon Sarl | Interspinous process implant and method of implantation |
US7833246B2 (en) | 2002-10-29 | 2010-11-16 | Kyphon SÀRL | Interspinous process and sacrum implant and method |
US7549999B2 (en) | 2003-05-22 | 2009-06-23 | Kyphon Sarl | Interspinous process distraction implant and method of implantation |
US7749252B2 (en) * | 2005-03-21 | 2010-07-06 | Kyphon Sarl | Interspinous process implant having deployable wing and method of implantation |
US8070778B2 (en) | 2003-05-22 | 2011-12-06 | Kyphon Sarl | Interspinous process implant with slide-in distraction piece and method of implantation |
US7335203B2 (en) | 2003-02-12 | 2008-02-26 | Kyphon Inc. | System and method for immobilizing adjacent spinous processes |
FR2851154B1 (en) * | 2003-02-19 | 2006-07-07 | Sdgi Holding Inc | INTER-SPINOUS DEVICE FOR BRAKING THE MOVEMENTS OF TWO SUCCESSIVE VERTEBRATES, AND METHOD FOR MANUFACTURING THE SAME THEREOF |
EP1677691B1 (en) * | 2003-10-30 | 2010-09-29 | Synthes GmbH | Intervertebral implant |
US7585316B2 (en) | 2004-05-21 | 2009-09-08 | Warsaw Orthopedic, Inc. | Interspinous spacer |
US7641690B2 (en) * | 2004-08-23 | 2010-01-05 | Abdou M Samy | Bone fixation and fusion device |
WO2006034436A2 (en) | 2004-09-21 | 2006-03-30 | Stout Medical Group, L.P. | Expandable support device and method of use |
US8012209B2 (en) | 2004-09-23 | 2011-09-06 | Kyphon Sarl | Interspinous process implant including a binder, binder aligner and method of implantation |
US7951153B2 (en) | 2004-10-05 | 2011-05-31 | Samy Abdou | Devices and methods for inter-vertebral orthopedic device placement |
US8123807B2 (en) | 2004-10-20 | 2012-02-28 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
US8128662B2 (en) | 2004-10-20 | 2012-03-06 | Vertiflex, Inc. | Minimally invasive tooling for delivery of interspinous spacer |
US8425559B2 (en) | 2004-10-20 | 2013-04-23 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
US7763074B2 (en) | 2004-10-20 | 2010-07-27 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
US8152837B2 (en) | 2004-10-20 | 2012-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
US8277488B2 (en) | 2004-10-20 | 2012-10-02 | Vertiflex, Inc. | Interspinous spacer |
US8167944B2 (en) | 2004-10-20 | 2012-05-01 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
WO2009009049A2 (en) | 2004-10-20 | 2009-01-15 | Vertiflex, Inc. | Interspinous spacer |
US9161783B2 (en) | 2004-10-20 | 2015-10-20 | Vertiflex, Inc. | Interspinous spacer |
US8267969B2 (en) | 2004-10-20 | 2012-09-18 | Exactech, Inc. | Screw systems and methods for use in stabilization of bone structures |
US9119680B2 (en) | 2004-10-20 | 2015-09-01 | Vertiflex, Inc. | Interspinous spacer |
US8613747B2 (en) | 2004-10-20 | 2013-12-24 | Vertiflex, Inc. | Spacer insertion instrument |
US9023084B2 (en) | 2004-10-20 | 2015-05-05 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for stabilizing the motion or adjusting the position of the spine |
US8945183B2 (en) | 2004-10-20 | 2015-02-03 | Vertiflex, Inc. | Interspinous process spacer instrument system with deployment indicator |
US8409282B2 (en) * | 2004-10-20 | 2013-04-02 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
US8012207B2 (en) | 2004-10-20 | 2011-09-06 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
US8317864B2 (en) * | 2004-10-20 | 2012-11-27 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
US8123782B2 (en) * | 2004-10-20 | 2012-02-28 | Vertiflex, Inc. | Interspinous spacer |
US8226690B2 (en) | 2005-07-22 | 2012-07-24 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for stabilization of bone structures |
US7918875B2 (en) * | 2004-10-25 | 2011-04-05 | Lanx, Inc. | Interspinous distraction devices and associated methods of insertion |
CA2614133A1 (en) | 2004-10-25 | 2006-05-04 | Lanx, Llc | Interspinous distraction devices and associated methods of insertion |
US9055981B2 (en) | 2004-10-25 | 2015-06-16 | Lanx, Inc. | Spinal implants and methods |
US8241330B2 (en) | 2007-01-11 | 2012-08-14 | Lanx, Inc. | Spinous process implants and associated methods |
US7887589B2 (en) * | 2004-11-23 | 2011-02-15 | Glenn Bradley J | Minimally invasive spinal disc stabilizer and insertion tool |
ATE524121T1 (en) * | 2004-11-24 | 2011-09-15 | Abdou Samy | DEVICES FOR PLACING AN ORTHOPEDIC INTERVERTEBRAL IMPLANT |
EP2219538B1 (en) | 2004-12-06 | 2022-07-06 | Vertiflex, Inc. | Spacer insertion instrument |
US8057513B2 (en) | 2005-02-17 | 2011-11-15 | Kyphon Sarl | Percutaneous spinal implants and methods |
US7998208B2 (en) | 2005-02-17 | 2011-08-16 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8157841B2 (en) | 2005-02-17 | 2012-04-17 | Kyphon Sarl | Percutaneous spinal implants and methods |
US7998174B2 (en) | 2005-02-17 | 2011-08-16 | Kyphon Sarl | Percutaneous spinal implants and methods |
US7988709B2 (en) | 2005-02-17 | 2011-08-02 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8043335B2 (en) * | 2005-02-17 | 2011-10-25 | Kyphon Sarl | Percutaneous spinal implants and methods |
US7927354B2 (en) | 2005-02-17 | 2011-04-19 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8096994B2 (en) | 2005-02-17 | 2012-01-17 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8038698B2 (en) * | 2005-02-17 | 2011-10-18 | Kphon Sarl | Percutaneous spinal implants and methods |
US7993342B2 (en) | 2005-02-17 | 2011-08-09 | Kyphon Sarl | Percutaneous spinal implants and methods |
US20070276373A1 (en) * | 2005-02-17 | 2007-11-29 | Malandain Hugues F | Percutaneous Spinal Implants and Methods |
US8007521B2 (en) | 2005-02-17 | 2011-08-30 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8092459B2 (en) | 2005-02-17 | 2012-01-10 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8034080B2 (en) | 2005-02-17 | 2011-10-11 | Kyphon Sarl | Percutaneous spinal implants and methods |
US20070276493A1 (en) | 2005-02-17 | 2007-11-29 | Malandain Hugues F | Percutaneous spinal implants and methods |
US8096995B2 (en) | 2005-02-17 | 2012-01-17 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8097018B2 (en) | 2005-02-17 | 2012-01-17 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8029567B2 (en) | 2005-02-17 | 2011-10-04 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8100943B2 (en) | 2005-02-17 | 2012-01-24 | Kyphon Sarl | Percutaneous spinal implants and methods |
US8066742B2 (en) * | 2005-03-31 | 2011-11-29 | Warsaw Orthopedic, Inc. | Intervertebral prosthetic device for spinal stabilization and method of implanting same |
US20060241757A1 (en) * | 2005-03-31 | 2006-10-26 | Sdgi Holdings, Inc. | Intervertebral prosthetic device for spinal stabilization and method of manufacturing same |
US7862590B2 (en) | 2005-04-08 | 2011-01-04 | Warsaw Orthopedic, Inc. | Interspinous process spacer |
US8034079B2 (en) | 2005-04-12 | 2011-10-11 | Warsaw Orthopedic, Inc. | Implants and methods for posterior dynamic stabilization of a spinal motion segment |
US7780709B2 (en) | 2005-04-12 | 2010-08-24 | Warsaw Orthopedic, Inc. | Implants and methods for inter-transverse process dynamic stabilization of a spinal motion segment |
FR2884406B1 (en) | 2005-04-14 | 2008-10-17 | Memometal Technologies Soc Par | INTRAMEDULAR OSTEOSYNTHESIS DEVICE OF TWO BONE PARTS, IN PARTICULAR HAND AND / OR FOOT |
US7789898B2 (en) * | 2005-04-15 | 2010-09-07 | Warsaw Orthopedic, Inc. | Transverse process/laminar spacer |
US7727233B2 (en) | 2005-04-29 | 2010-06-01 | Warsaw Orthopedic, Inc. | Spinous process stabilization devices and methods |
US7967844B2 (en) * | 2005-06-10 | 2011-06-28 | Depuy Spine, Inc. | Multi-level posterior dynamic stabilization systems and methods |
US20070005064A1 (en) * | 2005-06-27 | 2007-01-04 | Sdgi Holdings | Intervertebral prosthetic device for spinal stabilization and method of implanting same |
FR2887434B1 (en) | 2005-06-28 | 2008-03-28 | Jean Taylor | SURGICAL TREATMENT EQUIPMENT OF TWO VERTEBRATES |
WO2007009107A2 (en) | 2005-07-14 | 2007-01-18 | Stout Medical Group, P.L. | Expandable support device and method of use |
US8523865B2 (en) | 2005-07-22 | 2013-09-03 | Exactech, Inc. | Tissue splitter |
US7611537B2 (en) * | 2005-08-01 | 2009-11-03 | Warsaw Orthopedic, Inc. | System, device, and method for percutaneous interbody device and nucleus removal system |
FR2889438B1 (en) * | 2005-08-04 | 2008-06-06 | Scient X Sa | DOUBLE-SHAPED INTERVERTEBRAL IMPLANT |
US8870890B2 (en) * | 2005-08-05 | 2014-10-28 | DePuy Synthes Products, LLC | Pronged holder for treating spinal stenosis |
US7753938B2 (en) * | 2005-08-05 | 2010-07-13 | Synthes Usa, Llc | Apparatus for treating spinal stenosis |
WO2007044705A2 (en) | 2005-10-07 | 2007-04-19 | Abdou Samy M | Devices and methods for inter-verterbral orthopedic device placement |
US8267970B2 (en) * | 2005-10-25 | 2012-09-18 | Depuy Spine, Inc. | Laminar hook spring |
US8357181B2 (en) | 2005-10-27 | 2013-01-22 | Warsaw Orthopedic, Inc. | Intervertebral prosthetic device for spinal stabilization and method of implanting same |
US7862591B2 (en) | 2005-11-10 | 2011-01-04 | Warsaw Orthopedic, Inc. | Intervertebral prosthetic device for spinal stabilization and method of implanting same |
US8430911B2 (en) * | 2005-12-14 | 2013-04-30 | Spinefrontier Inc | Spinous process fixation implant |
AU2013273815B2 (en) * | 2005-12-20 | 2016-01-07 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
US7585313B2 (en) * | 2005-12-22 | 2009-09-08 | Depuy Spine, Inc. | Rotatable interspinous spacer |
US7922745B2 (en) * | 2006-01-09 | 2011-04-12 | Zimmer Spine, Inc. | Posterior dynamic stabilization of the spine |
US20070173823A1 (en) * | 2006-01-18 | 2007-07-26 | Sdgi Holdings, Inc. | Intervertebral prosthetic device for spinal stabilization and method of implanting same |
US8083795B2 (en) * | 2006-01-18 | 2011-12-27 | Warsaw Orthopedic, Inc. | Intervertebral prosthetic device for spinal stabilization and method of manufacturing same |
US8758409B2 (en) * | 2006-01-23 | 2014-06-24 | Pioneer Surgical Technology, Inc. | Interlaminar stabilizing system |
US20070233084A1 (en) * | 2006-01-25 | 2007-10-04 | Spinemedica Corporation | Implantable spinous process prosthetic devices, including cuffs, and methods of fabricating same |
US7682376B2 (en) | 2006-01-27 | 2010-03-23 | Warsaw Orthopedic, Inc. | Interspinous devices and methods of use |
US7837711B2 (en) | 2006-01-27 | 2010-11-23 | Warsaw Orthopedic, Inc. | Artificial spinous process for the sacrum and methods of use |
US7815663B2 (en) | 2006-01-27 | 2010-10-19 | Warsaw Orthopedic, Inc. | Vertebral rods and methods of use |
US7691130B2 (en) | 2006-01-27 | 2010-04-06 | Warsaw Orthopedic, Inc. | Spinal implants including a sensor and methods of use |
WO2007089905A2 (en) | 2006-02-01 | 2007-08-09 | Synthes (U.S.A.) | Interspinous process spacer |
US8262698B2 (en) * | 2006-03-16 | 2012-09-11 | Warsaw Orthopedic, Inc. | Expandable device for insertion between anatomical structures and a procedure utilizing same |
US7871426B2 (en) * | 2006-03-21 | 2011-01-18 | Spinefrontier, LLS | Spinous process fixation device |
US8361116B2 (en) * | 2006-03-24 | 2013-01-29 | U.S. Spine, Inc. | Non-pedicle based interspinous spacer |
US7985246B2 (en) * | 2006-03-31 | 2011-07-26 | Warsaw Orthopedic, Inc. | Methods and instruments for delivering interspinous process spacers |
US8118844B2 (en) | 2006-04-24 | 2012-02-21 | Warsaw Orthopedic, Inc. | Expandable device for insertion between anatomical structures and a procedure utilizing same |
US20070270824A1 (en) * | 2006-04-28 | 2007-11-22 | Warsaw Orthopedic, Inc. | Interspinous process brace |
US8252031B2 (en) | 2006-04-28 | 2012-08-28 | Warsaw Orthopedic, Inc. | Molding device for an expandable interspinous process implant |
DE102007018860B4 (en) | 2006-04-28 | 2023-01-05 | Paradigm Spine L.L.C. | Instrument system for use with an interspinous implant |
US20070270823A1 (en) | 2006-04-28 | 2007-11-22 | Sdgi Holdings, Inc. | Multi-chamber expandable interspinous process brace |
US8048118B2 (en) | 2006-04-28 | 2011-11-01 | Warsaw Orthopedic, Inc. | Adjustable interspinous process brace |
US8348978B2 (en) | 2006-04-28 | 2013-01-08 | Warsaw Orthopedic, Inc. | Interosteotic implant |
US7846185B2 (en) | 2006-04-28 | 2010-12-07 | Warsaw Orthopedic, Inc. | Expandable interspinous process implant and method of installing same |
US8105357B2 (en) | 2006-04-28 | 2012-01-31 | Warsaw Orthopedic, Inc. | Interspinous process brace |
WO2007131002A2 (en) | 2006-05-01 | 2007-11-15 | Stout Medical Group, L.P. | Expandable support device and method of use |
US8062337B2 (en) | 2006-05-04 | 2011-11-22 | Warsaw Orthopedic, Inc. | Expandable device for insertion between anatomical structures and a procedure utilizing same |
US8012179B2 (en) * | 2006-05-08 | 2011-09-06 | Warsaw Orthopedic, Inc. | Dynamic spinal stabilization members and methods |
US8147517B2 (en) | 2006-05-23 | 2012-04-03 | Warsaw Orthopedic, Inc. | Systems and methods for adjusting properties of a spinal implant |
US20070276496A1 (en) | 2006-05-23 | 2007-11-29 | Sdgi Holdings, Inc. | Surgical spacer with shape control |
US8048119B2 (en) * | 2006-07-20 | 2011-11-01 | Warsaw Orthopedic, Inc. | Apparatus for insertion between anatomical structures and a procedure utilizing same |
US20080082104A1 (en) | 2006-07-27 | 2008-04-03 | Lanx, Llc | Methods and apparatuses for facilitating percutaneous fusion |
WO2008013960A2 (en) | 2006-07-27 | 2008-01-31 | Abdou Samy M | Devices and methods for the minimally invasive treatment of spinal stenosis |
US20080086115A1 (en) | 2006-09-07 | 2008-04-10 | Warsaw Orthopedic, Inc. | Intercostal spacer device and method for use in correcting a spinal deformity |
US8444682B2 (en) * | 2006-09-13 | 2013-05-21 | The University Of Hong Kong | Shape memory locking device for orthopedic implants |
US9017388B2 (en) * | 2006-09-14 | 2015-04-28 | Warsaw Orthopedic, Inc. | Methods for correcting spinal deformities |
US8845726B2 (en) | 2006-10-18 | 2014-09-30 | Vertiflex, Inc. | Dilator |
US8097019B2 (en) * | 2006-10-24 | 2012-01-17 | Kyphon Sarl | Systems and methods for in situ assembly of an interspinous process distraction implant |
US8096996B2 (en) | 2007-03-20 | 2012-01-17 | Exactech, Inc. | Rod reducer |
FR2908035B1 (en) | 2006-11-08 | 2009-05-01 | Jean Taylor | INTEREPINE IMPLANT |
US7879104B2 (en) | 2006-11-15 | 2011-02-01 | Warsaw Orthopedic, Inc. | Spinal implant system |
US20080114357A1 (en) * | 2006-11-15 | 2008-05-15 | Warsaw Orthopedic, Inc. | Inter-transverse process spacer device and method for use in correcting a spinal deformity |
US8105382B2 (en) | 2006-12-07 | 2012-01-31 | Interventional Spine, Inc. | Intervertebral implant |
DE102006059395A1 (en) * | 2006-12-08 | 2008-06-19 | Aesculap Ag & Co. Kg | Implant and implant system |
US7955392B2 (en) | 2006-12-14 | 2011-06-07 | Warsaw Orthopedic, Inc. | Interspinous process devices and methods |
US9039768B2 (en) | 2006-12-22 | 2015-05-26 | Medos International Sarl | Composite vertebral spacers and instrument |
US20080167657A1 (en) * | 2006-12-31 | 2008-07-10 | Stout Medical Group, L.P. | Expandable support device and method of use |
US8974496B2 (en) | 2007-08-30 | 2015-03-10 | Jeffrey Chun Wang | Interspinous implant, tools and methods of implanting |
US9265532B2 (en) | 2007-01-11 | 2016-02-23 | Lanx, Inc. | Interspinous implants and methods |
US8672976B2 (en) | 2007-02-06 | 2014-03-18 | Pioneer Surgical Technology, Inc. | Intervertebral implant devices and methods for insertion thereof |
WO2008106140A2 (en) | 2007-02-26 | 2008-09-04 | Abdou M Samy | Spinal stabilization systems and methods of use |
FR2913876B1 (en) * | 2007-03-20 | 2009-06-05 | Memometal Technologies Soc Par | OSTEOSYNTHESIS DEVICE |
WO2008124802A2 (en) * | 2007-04-10 | 2008-10-16 | Medicinelodge, Inc. | Interspinous process spacers |
EP2155121B1 (en) | 2007-04-16 | 2015-06-17 | Vertiflex, Inc. | Interspinous spacer |
US20080262619A1 (en) * | 2007-04-18 | 2008-10-23 | Ray Charles D | Interspinous process cushioned spacer |
US7799058B2 (en) * | 2007-04-19 | 2010-09-21 | Zimmer Gmbh | Interspinous spacer |
US20090012614A1 (en) * | 2007-05-08 | 2009-01-08 | Dixon Robert A | Device and method for tethering a spinal implant |
US9173686B2 (en) * | 2007-05-09 | 2015-11-03 | Ebi, Llc | Interspinous implant |
US9381047B2 (en) | 2007-05-09 | 2016-07-05 | Ebi, Llc | Interspinous implant |
US8840646B2 (en) | 2007-05-10 | 2014-09-23 | Warsaw Orthopedic, Inc. | Spinous process implants and methods |
US8070779B2 (en) * | 2007-06-04 | 2011-12-06 | K2M, Inc. | Percutaneous interspinous process device and method |
US8900307B2 (en) | 2007-06-26 | 2014-12-02 | DePuy Synthes Products, LLC | Highly lordosed fusion cage |
US8348976B2 (en) | 2007-08-27 | 2013-01-08 | Kyphon Sarl | Spinous-process implants and methods of using the same |
CA2698718C (en) * | 2007-09-07 | 2015-10-06 | Vertiflex, Inc. | Interspinous spacer |
US8308767B2 (en) | 2007-09-19 | 2012-11-13 | Pioneer Surgical Technology, Inc. | Interlaminar stabilization system |
US8177813B2 (en) * | 2007-09-20 | 2012-05-15 | Life Spine, Inc. | Expandable spinal spacer |
US20090105773A1 (en) * | 2007-10-23 | 2009-04-23 | Warsaw Orthopedic, Inc. | Method and apparatus for insertion of an interspinous process device |
US20090118833A1 (en) * | 2007-11-05 | 2009-05-07 | Zimmer Spine, Inc. | In-situ curable interspinous process spacer |
US8758439B2 (en) | 2007-11-19 | 2014-06-24 | Linares Medical Devices, Llc | Spine support implant including inter vertebral insertable fluid ballastable insert and inter-vertebral web retaining harnesses |
US8888850B2 (en) * | 2007-11-19 | 2014-11-18 | Linares Medical Devices, Llc | Combination spacer insert and support for providing inter-cervical vertebral support |
US20090131984A1 (en) * | 2007-11-19 | 2009-05-21 | Linares Miguel A | Spine support implant including inter vertebral insertable fluid ballastable insert and inter-vertebral web retaining harnesses |
EP2244670B1 (en) | 2008-01-15 | 2017-09-13 | Vertiflex, Inc. | Interspinous spacer |
CN101909548B (en) | 2008-01-17 | 2014-07-30 | 斯恩蒂斯有限公司 | An expandable intervertebral implant and associated method of manufacturing the same |
US8105358B2 (en) | 2008-02-04 | 2012-01-31 | Kyphon Sarl | Medical implants and methods |
US8252029B2 (en) * | 2008-02-21 | 2012-08-28 | Zimmer Gmbh | Expandable interspinous process spacer with lateral support and method for implantation |
US8114136B2 (en) | 2008-03-18 | 2012-02-14 | Warsaw Orthopedic, Inc. | Implants and methods for inter-spinous process dynamic stabilization of a spinal motion segment |
US8202299B2 (en) | 2008-03-19 | 2012-06-19 | Collabcom II, LLC | Interspinous implant, tools and methods of implanting |
US20090248092A1 (en) | 2008-03-26 | 2009-10-01 | Jonathan Bellas | Posterior Intervertebral Disc Inserter and Expansion Techniques |
WO2009124269A1 (en) | 2008-04-05 | 2009-10-08 | Synthes Usa, Llc | Expandable intervertebral implant |
KR101547212B1 (en) * | 2008-04-22 | 2015-08-25 | 키네틱 스파인 테크놀로지스 인크. | Artificial intervertebral spacer |
US9398926B2 (en) * | 2008-05-05 | 2016-07-26 | Industrial Technology Research Institute | Interspinous stabilization device |
DE102008032685B4 (en) * | 2008-07-04 | 2016-06-23 | Aesculap Ag | Implant for mutual support of spinous processes of vertebral bodies |
FR2935601B1 (en) | 2008-09-09 | 2010-10-01 | Memometal Technologies | INTRAMEDULLARY IMPLANT RESORBABLE BETWEEN TWO BONE OR TWO BONE FRAGMENTS |
US8623056B2 (en) | 2008-10-23 | 2014-01-07 | Linares Medical Devices, Llc | Support insert associated with spinal vertebrae |
US8114131B2 (en) | 2008-11-05 | 2012-02-14 | Kyphon Sarl | Extension limiting devices and methods of use for the spine |
US9084638B2 (en) | 2008-11-10 | 2015-07-21 | Linares Medical Devices, Llc | Implant for providing inter-vertebral support and for relieving pinching of the spinal nerves |
US20100121239A1 (en) * | 2008-11-10 | 2010-05-13 | Linares Medical Devices, Llc | Support including stabilizing brace and inserts for use with any number of spinal vertebrae such as upper thoracic vertebrae |
US20100211176A1 (en) | 2008-11-12 | 2010-08-19 | Stout Medical Group, L.P. | Fixation device and method |
US20100204795A1 (en) | 2008-11-12 | 2010-08-12 | Stout Medical Group, L.P. | Fixation device and method |
US8216278B2 (en) | 2008-12-22 | 2012-07-10 | Synthes Usa, Llc | Expandable interspinous process spacer |
US8114135B2 (en) | 2009-01-16 | 2012-02-14 | Kyphon Sarl | Adjustable surgical cables and methods for treating spinal stenosis |
WO2010085809A1 (en) * | 2009-01-26 | 2010-07-29 | Life Spine, Inc. | Flexible and static interspinous/inter-laminar spinal spacers |
US10052139B2 (en) | 2009-01-26 | 2018-08-21 | Life Spine, Inc. | Flexible and static interspinous/inter-laminar spinal spacers |
US9526620B2 (en) | 2009-03-30 | 2016-12-27 | DePuy Synthes Products, Inc. | Zero profile spinal fusion cage |
BRPI1014864A2 (en) | 2009-03-31 | 2017-03-28 | Lanx Inc | "implantation of spinous processes and associated methods" |
US8372117B2 (en) | 2009-06-05 | 2013-02-12 | Kyphon Sarl | Multi-level interspinous implants and methods of use |
US8157842B2 (en) | 2009-06-12 | 2012-04-17 | Kyphon Sarl | Interspinous implant and methods of use |
EP2475334A4 (en) * | 2009-09-11 | 2014-10-22 | Articulinx Inc | Disc-shaped orthopedic devices |
US9149305B2 (en) * | 2009-10-14 | 2015-10-06 | Latitude Holdings, Llc | Spinous process fixation plate and minimally invasive method for placement |
US8771317B2 (en) | 2009-10-28 | 2014-07-08 | Warsaw Orthopedic, Inc. | Interspinous process implant and method of implantation |
JP2013509959A (en) * | 2009-11-06 | 2013-03-21 | ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング | Minimally invasive interspinous spacer implant and method |
US8795335B1 (en) | 2009-11-06 | 2014-08-05 | Samy Abdou | Spinal fixation devices and methods of use |
US8764806B2 (en) | 2009-12-07 | 2014-07-01 | Samy Abdou | Devices and methods for minimally invasive spinal stabilization and instrumentation |
US9393129B2 (en) | 2009-12-10 | 2016-07-19 | DePuy Synthes Products, Inc. | Bellows-like expandable interbody fusion cage |
US8740948B2 (en) | 2009-12-15 | 2014-06-03 | Vertiflex, Inc. | Spinal spacer for cervical and other vertebra, and associated systems and methods |
US8317831B2 (en) | 2010-01-13 | 2012-11-27 | Kyphon Sarl | Interspinous process spacer diagnostic balloon catheter and methods of use |
US8114132B2 (en) | 2010-01-13 | 2012-02-14 | Kyphon Sarl | Dynamic interspinous process device |
US8262697B2 (en) | 2010-01-14 | 2012-09-11 | X-Spine Systems, Inc. | Modular interspinous fixation system and method |
DE102010000230A1 (en) | 2010-01-27 | 2011-07-28 | Aesculap AG, 78532 | Surgical instruments |
DE102010000231A1 (en) | 2010-01-27 | 2011-07-28 | Aesculap AG, 78532 | Implant for the mutual support of spinous processes of adjacent vertebral bodies and surgical system |
US8388656B2 (en) * | 2010-02-04 | 2013-03-05 | Ebi, Llc | Interspinous spacer with deployable members and related method |
US8834568B2 (en) * | 2010-02-04 | 2014-09-16 | Paul S. Shapiro | Surgical technique using a contoured allograft cartilage as a spacer of the carpo-metacarpal joint of the thumb or tarso-metatarsal joint of the toe |
US8147526B2 (en) | 2010-02-26 | 2012-04-03 | Kyphon Sarl | Interspinous process spacer diagnostic parallel balloon catheter and methods of use |
US8876870B2 (en) * | 2010-04-27 | 2014-11-04 | Adnan Iqbal Qureshi | Intraspinal device deployed through percutaneous approach into subarachnoid or intradural space of vertebral canal to protect spinal cord from external compression |
US8535380B2 (en) | 2010-05-13 | 2013-09-17 | Stout Medical Group, L.P. | Fixation device and method |
US9724140B2 (en) | 2010-06-02 | 2017-08-08 | Wright Medical Technology, Inc. | Tapered, cylindrical cruciform hammer toe implant and method |
US8608785B2 (en) | 2010-06-02 | 2013-12-17 | Wright Medical Technology, Inc. | Hammer toe implant with expansion portion for retrograde approach |
US9498273B2 (en) | 2010-06-02 | 2016-11-22 | Wright Medical Technology, Inc. | Orthopedic implant kit |
US9072564B2 (en) | 2010-06-02 | 2015-07-07 | Wright Medical Technology, Inc. | Hammer toe implant and method |
US9907560B2 (en) | 2010-06-24 | 2018-03-06 | DePuy Synthes Products, Inc. | Flexible vertebral body shavers |
US8979860B2 (en) | 2010-06-24 | 2015-03-17 | DePuy Synthes Products. LLC | Enhanced cage insertion device |
TW201215379A (en) | 2010-06-29 | 2012-04-16 | Synthes Gmbh | Distractible intervertebral implant |
US8814908B2 (en) | 2010-07-26 | 2014-08-26 | Warsaw Orthopedic, Inc. | Injectable flexible interspinous process device system |
EP2608747A4 (en) | 2010-08-24 | 2015-02-11 | Flexmedex Llc | Support device and method for use |
US20120078372A1 (en) | 2010-09-23 | 2012-03-29 | Thomas Gamache | Novel implant inserter having a laterally-extending dovetail engagement feature |
US20120078373A1 (en) | 2010-09-23 | 2012-03-29 | Thomas Gamache | Stand alone intervertebral fusion device |
US11529241B2 (en) | 2010-09-23 | 2022-12-20 | DePuy Synthes Products, Inc. | Fusion cage with in-line single piece fixation |
KR101872045B1 (en) * | 2010-09-30 | 2018-06-27 | 스피네벨딩 아게 | Anterior cervical plate |
US9402732B2 (en) | 2010-10-11 | 2016-08-02 | DePuy Synthes Products, Inc. | Expandable interspinous process spacer implant |
US9149286B1 (en) | 2010-11-12 | 2015-10-06 | Flexmedex, LLC | Guidance tool and method for use |
US8512408B2 (en) | 2010-12-17 | 2013-08-20 | Warsaw Orthopedic, Inc. | Flexiable spinal implant |
US8496689B2 (en) | 2011-02-23 | 2013-07-30 | Farzad Massoudi | Spinal implant device with fusion cage and fixation plates and method of implanting |
US8562650B2 (en) | 2011-03-01 | 2013-10-22 | Warsaw Orthopedic, Inc. | Percutaneous spinous process fusion plate assembly and method |
US8425560B2 (en) | 2011-03-09 | 2013-04-23 | Farzad Massoudi | Spinal implant device with fixation plates and lag screws and method of implanting |
US8591548B2 (en) | 2011-03-31 | 2013-11-26 | Warsaw Orthopedic, Inc. | Spinous process fusion plate assembly |
US8591549B2 (en) | 2011-04-08 | 2013-11-26 | Warsaw Orthopedic, Inc. | Variable durometer lumbar-sacral implant |
US20120323276A1 (en) * | 2011-06-17 | 2012-12-20 | Bryan Okamoto | Expandable interspinous device |
US9149306B2 (en) | 2011-06-21 | 2015-10-06 | Seaspine, Inc. | Spinous process device |
FR2977139B1 (en) | 2011-06-30 | 2014-08-22 | Ldr Medical | INTER-SPINAL IMPLANT AND IMPLANTATION INSTRUMENT |
WO2013006830A1 (en) * | 2011-07-07 | 2013-01-10 | Samy Abdou | Devices and methods to prevent or limit spondlylolisthesis and other aberrant movements of the vertebral bones |
WO2013028808A1 (en) | 2011-08-23 | 2013-02-28 | Flexmedex, LLC | Tissue removal device and method |
US8845728B1 (en) | 2011-09-23 | 2014-09-30 | Samy Abdou | Spinal fixation devices and methods of use |
US11812923B2 (en) | 2011-10-07 | 2023-11-14 | Alan Villavicencio | Spinal fixation device |
US9119683B2 (en) | 2012-01-18 | 2015-09-01 | Warsaw Orthopedic, Inc. | Interspinous implant with overlapping arms |
US9204959B2 (en) * | 2012-02-02 | 2015-12-08 | Smith & Nephew, Inc. | Implantable biologic holder |
US20130226240A1 (en) | 2012-02-22 | 2013-08-29 | Samy Abdou | Spinous process fixation devices and methods of use |
US9271836B2 (en) | 2012-03-06 | 2016-03-01 | DePuy Synthes Products, Inc. | Nubbed plate |
JP6148330B2 (en) | 2012-05-11 | 2017-06-14 | アエスキュラップ アーゲー | Implants for stabilizing spinous processes |
WO2013177314A1 (en) * | 2012-05-22 | 2013-11-28 | The Regents Of The University Of California | A method and device for restabilization with axial rotation of the atlantoaxial junction |
US9248026B2 (en) * | 2012-08-23 | 2016-02-02 | DePuy Synthes Products, Inc. | Surface expanding spacer |
US9198767B2 (en) | 2012-08-28 | 2015-12-01 | Samy Abdou | Devices and methods for spinal stabilization and instrumentation |
US9320617B2 (en) | 2012-10-22 | 2016-04-26 | Cogent Spine, LLC | Devices and methods for spinal stabilization and instrumentation |
US10182921B2 (en) | 2012-11-09 | 2019-01-22 | DePuy Synthes Products, Inc. | Interbody device with opening to allow packing graft and other biologics |
US8945232B2 (en) | 2012-12-31 | 2015-02-03 | Wright Medical Technology, Inc. | Ball and socket implants for correction of hammer toes and claw toes |
US9522070B2 (en) | 2013-03-07 | 2016-12-20 | Interventional Spine, Inc. | Intervertebral implant |
US9675303B2 (en) | 2013-03-15 | 2017-06-13 | Vertiflex, Inc. | Visualization systems, instruments and methods of using the same in spinal decompression procedures |
US9724139B2 (en) | 2013-10-01 | 2017-08-08 | Wright Medical Technology, Inc. | Hammer toe implant and method |
US9474561B2 (en) | 2013-11-19 | 2016-10-25 | Wright Medical Technology, Inc. | Two-wire technique for installing hammertoe implant |
US9615935B2 (en) * | 2014-01-30 | 2017-04-11 | Titan Spine, Llc | Thermally activated shape memory spring assemblies for implant expansion |
US9545274B2 (en) | 2014-02-12 | 2017-01-17 | Wright Medical Technology, Inc. | Intramedullary implant, system, and method for inserting an implant into a bone |
US9498266B2 (en) * | 2014-02-12 | 2016-11-22 | Wright Medical Technology, Inc. | Intramedullary implant, system, and method for inserting an implant into a bone |
AU2015256024B2 (en) | 2014-05-07 | 2020-03-05 | Vertiflex, Inc. | Spinal nerve decompression systems, dilation systems, and methods of using the same |
WO2016043751A1 (en) | 2014-09-18 | 2016-03-24 | Wright Medical Technology, Inc. | Hammertoe implant and instrument |
CN105960211B (en) | 2014-12-19 | 2019-01-11 | 瑞特医疗技术公司 | For anchor log in the marrow of interphalangeal arthrodesis of toe |
WO2016137983A1 (en) | 2015-02-24 | 2016-09-01 | X-Spine Systems, Inc. | Modular interspinous fixation system with threaded component |
US9757168B2 (en) | 2015-03-03 | 2017-09-12 | Howmedica Osteonics Corp. | Orthopedic implant and methods of implanting and removing same |
US11426290B2 (en) | 2015-03-06 | 2022-08-30 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
US10918841B2 (en) * | 2015-03-31 | 2021-02-16 | Mar-Med Co. | Abscess drainage |
US10857003B1 (en) | 2015-10-14 | 2020-12-08 | Samy Abdou | Devices and methods for vertebral stabilization |
US10335207B2 (en) | 2015-12-29 | 2019-07-02 | Nuvasive, Inc. | Spinous process plate fixation assembly |
EP3251621B1 (en) | 2016-06-03 | 2021-01-20 | Stryker European Holdings I, LLC | Intramedullary implant |
JP6995789B2 (en) | 2016-06-28 | 2022-01-17 | イーアイティー・エマージング・インプラント・テクノロジーズ・ゲーエムベーハー | Expandable and angle adjustable intervertebral cage |
JP7019616B2 (en) | 2016-06-28 | 2022-02-15 | イーアイティー・エマージング・インプラント・テクノロジーズ・ゲーエムベーハー | Expandable and angle adjustable intervertebral cage with range of motion joints |
US10034693B2 (en) | 2016-07-07 | 2018-07-31 | Mark S. Stern | Spinous laminar clamp assembly |
US10973648B1 (en) | 2016-10-25 | 2021-04-13 | Samy Abdou | Devices and methods for vertebral bone realignment |
US10744000B1 (en) | 2016-10-25 | 2020-08-18 | Samy Abdou | Devices and methods for vertebral bone realignment |
TWI627935B (en) * | 2017-01-24 | 2018-07-01 | 好喜歡妮有限公司 | Interspinous stabilizer |
CN106901877A (en) * | 2017-04-10 | 2017-06-30 | 北京大学人民医院 | A kind of assembly type artificial vertebral body |
US10398563B2 (en) | 2017-05-08 | 2019-09-03 | Medos International Sarl | Expandable cage |
US11344424B2 (en) | 2017-06-14 | 2022-05-31 | Medos International Sarl | Expandable intervertebral implant and related methods |
US10940016B2 (en) | 2017-07-05 | 2021-03-09 | Medos International Sarl | Expandable intervertebral fusion cage |
US11931269B2 (en) * | 2017-07-10 | 2024-03-19 | Xtant Medical, Inc. | Delivery systems for interspinous, interlaminar stabilization devices and methods of use |
JP2020533070A (en) | 2017-09-08 | 2020-11-19 | パイオニア サージカル テクノロジー インコーポレイテッド | Intervertebral implants, instruments, and methods |
USD907771S1 (en) | 2017-10-09 | 2021-01-12 | Pioneer Surgical Technology, Inc. | Intervertebral implant |
US10973658B2 (en) | 2017-11-27 | 2021-04-13 | Titan Spine, Inc. | Rotating implant and associated instrumentation |
US11179248B2 (en) | 2018-10-02 | 2021-11-23 | Samy Abdou | Devices and methods for spinal implantation |
EP3863544B1 (en) * | 2018-10-04 | 2023-01-18 | G & G S.R.L. | Improved interlaminar-type intervertebral support device |
US11446156B2 (en) | 2018-10-25 | 2022-09-20 | Medos International Sarl | Expandable intervertebral implant, inserter instrument, and related methods |
US11426286B2 (en) | 2020-03-06 | 2022-08-30 | Eit Emerging Implant Technologies Gmbh | Expandable intervertebral implant |
KR102490198B1 (en) * | 2020-05-07 | 2023-01-19 | 신승준 | Endoscopic Interspinous Insert |
US11850160B2 (en) | 2021-03-26 | 2023-12-26 | Medos International Sarl | Expandable lordotic intervertebral fusion cage |
US11752009B2 (en) | 2021-04-06 | 2023-09-12 | Medos International Sarl | Expandable intervertebral fusion cage |
TWI784572B (en) * | 2021-06-16 | 2022-11-21 | 兆峰生技股份有限公司 | Spinous process expanding and supporting device and method |
Family Cites Families (172)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2677369A (en) | 1952-03-26 | 1954-05-04 | Fred L Knowles | Apparatus for treatment of the spinal column |
US3648691A (en) | 1970-02-24 | 1972-03-14 | Univ Colorado State Res Found | Method of applying vertebral appliance |
US4011602A (en) | 1975-10-06 | 1977-03-15 | Battelle Memorial Institute | Porous expandable device for attachment to bone tissue |
PL114098B1 (en) | 1978-04-14 | 1981-01-31 | Wyzsza Szkola Inzynierska | Apparatus for correcting spinal curvature |
CH628803A5 (en) | 1978-05-12 | 1982-03-31 | Sulzer Ag | Implant insertable between adjacent vertebrae |
SU988281A1 (en) | 1981-06-26 | 1983-01-15 | За витель | Vertical column fixing device |
US4554914A (en) | 1983-10-04 | 1985-11-26 | Kapp John P | Prosthetic vertebral body |
GB8333442D0 (en) | 1983-12-15 | 1984-01-25 | Showell A W Sugicraft Ltd | Devices for spinal fixation |
US4604995A (en) | 1984-03-30 | 1986-08-12 | Stephens David C | Spinal stabilizer |
US4573454A (en) | 1984-05-17 | 1986-03-04 | Hoffman Gregory A | Spinal fixation apparatus |
FR2575059B1 (en) | 1984-12-21 | 1988-11-10 | Daher Youssef | SHORING DEVICE FOR USE IN A VERTEBRAL PROSTHESIS |
SE458417B (en) | 1985-08-15 | 1989-04-03 | Sven Olerud | FIXING INSTRUMENTS PROVIDED FOR USE IN SPINE OPERATIONS |
EP0267959A1 (en) | 1986-05-30 | 1988-05-25 | BUMPUS, John | Distraction rods |
GB8620937D0 (en) | 1986-08-29 | 1986-10-08 | Shepperd J A N | Spinal implant |
FR2623085B1 (en) | 1987-11-16 | 1992-08-14 | Breard Francis | SURGICAL IMPLANT TO LIMIT THE RELATIVE MOVEMENT OF VERTEBRES |
FR2625097B1 (en) | 1987-12-23 | 1990-05-18 | Cote Sarl | INTER-SPINOUS PROSTHESIS COMPOSED OF SEMI-ELASTIC MATERIAL COMPRISING A TRANSFILING EYE AT ITS END AND INTER-SPINOUS PADS |
US5609635A (en) | 1988-06-28 | 1997-03-11 | Michelson; Gary K. | Lordotic interbody spinal fusion implants |
GB8825909D0 (en) | 1988-11-04 | 1988-12-07 | Showell A W Sugicraft Ltd | Pedicle engaging means |
US5201734A (en) | 1988-12-21 | 1993-04-13 | Zimmer, Inc. | Spinal locking sleeve assembly |
FR2642645B1 (en) | 1989-02-03 | 1992-08-14 | Breard Francis | FLEXIBLE INTERVERTEBRAL STABILIZER AND METHOD AND APPARATUS FOR CONTROLLING ITS VOLTAGE BEFORE PLACEMENT ON THE RACHIS |
US5098433A (en) | 1989-04-12 | 1992-03-24 | Yosef Freedland | Winged compression bolt orthopedic fastener |
DE3922044A1 (en) | 1989-07-05 | 1991-02-07 | Richter Turtur Matthias Dr | Treatment of fractured vertebra - by instrument which avoids any force on intact adjacent to vertebrae |
US5059193A (en) | 1989-11-20 | 1991-10-22 | Spine-Tech, Inc. | Expandable spinal implant and surgical method |
US5345927A (en) | 1990-03-02 | 1994-09-13 | Bonutti Peter M | Arthroscopic retractors |
DE4012622C1 (en) | 1990-04-20 | 1991-07-18 | Eska Medical Luebeck Medizintechnik Gmbh & Co, 2400 Luebeck, De | Two-part metal vertebra implant - has parts locked by two toothed racks, pre-stressed by elastic cushion between both implant parts |
US5047055A (en) | 1990-12-21 | 1991-09-10 | Pfizer Hospital Products Group, Inc. | Hydrogel intervertebral disc nucleus |
US5390683A (en) | 1991-02-22 | 1995-02-21 | Pisharodi; Madhavan | Spinal implantation methods utilizing a middle expandable implant |
US5171278A (en) | 1991-02-22 | 1992-12-15 | Madhavan Pisharodi | Middle expandable intervertebral disk implants |
FR2681525A1 (en) | 1991-09-19 | 1993-03-26 | Medical Op | Device for flexible or semi-rigid stabilisation of the spine, in particular of the human spine, by a posterior route |
CH686610A5 (en) | 1991-10-18 | 1996-05-15 | Pina Vertriebs Ag | Compression implant. |
FR2693364B1 (en) | 1992-07-07 | 1995-06-30 | Erpios Snc | INTERVERTEBRAL PROSTHESIS FOR STABILIZING ROTATORY AND FLEXIBLE-EXTENSION CONSTRAINTS. |
DE9213656U1 (en) | 1992-10-09 | 1992-12-03 | Angiomed Ag, 7500 Karlsruhe, De | |
DE69330909T2 (en) | 1992-11-12 | 2002-06-20 | Neville Alleyne | HEART PROTECTION DEVICE |
US5306275A (en) | 1992-12-31 | 1994-04-26 | Bryan Donald W | Lumbar spine fixation apparatus and method |
US5540703A (en) | 1993-01-06 | 1996-07-30 | Smith & Nephew Richards Inc. | Knotted cable attachment apparatus formed of braided polymeric fibers |
US5496318A (en) | 1993-01-08 | 1996-03-05 | Advanced Spine Fixation Systems, Inc. | Interspinous segmental spine fixation device |
FR2700941A1 (en) | 1993-02-03 | 1994-08-05 | Felman Daniel | Monobloc interspinal intervertebral fixation implant |
US5415661A (en) | 1993-03-24 | 1995-05-16 | University Of Miami | Implantable spinal assist device |
FR2703239B1 (en) | 1993-03-30 | 1995-06-02 | Brio Bio Rhone Implant Medical | Clip for interspinous prosthesis. |
FR2707864B1 (en) | 1993-07-23 | 1996-07-19 | Jean Taylor | Surgical forceps for tensioning an osteosynthesis ligament. |
US5360430A (en) | 1993-07-29 | 1994-11-01 | Lin Chih I | Intervertebral locking device |
US5454812A (en) | 1993-11-12 | 1995-10-03 | Lin; Chih-I | Spinal clamping device having multiple distance adjusting strands |
FR2715293B1 (en) | 1994-01-26 | 1996-03-22 | Biomat | Vertebral interbody fusion cage. |
FR2717675B1 (en) | 1994-03-24 | 1996-05-03 | Jean Taylor | Interspinous wedge. |
FR2719763B1 (en) | 1994-05-11 | 1996-09-27 | Jean Taylor | Vertebral implant. |
JP2793771B2 (en) * | 1994-05-12 | 1998-09-03 | 碩夫 福与 | Medical coupling fixture |
FR2721501B1 (en) | 1994-06-24 | 1996-08-23 | Fairant Paulette | Prostheses of the vertebral articular facets. |
FR2722088B1 (en) | 1994-07-08 | 1998-01-23 | Cahlik Marc Andre | SURGICAL IMPLANT FOR STABILIZING THE INTERVERTEBRAL SPACE |
FR2722087A1 (en) | 1994-07-08 | 1996-01-12 | Cahlik Marc Andre | Surgical implant for limiting relative movement of vertebrae |
FR2722980B1 (en) | 1994-07-26 | 1996-09-27 | Samani Jacques | INTERTEPINOUS VERTEBRAL IMPLANT |
ATE203885T1 (en) | 1994-09-08 | 2001-08-15 | Stryker Technologies Corp | HYDROGEL DISC CORE |
FR2724554B1 (en) | 1994-09-16 | 1997-01-24 | Voydeville Gilles | DEVICE FOR FIXING A LIGAMENT PROSTHESIS |
WO1996011642A1 (en) | 1994-10-17 | 1996-04-25 | Raymedica, Inc. | Prosthetic spinal disc nucleus |
FR2725892A1 (en) | 1994-10-21 | 1996-04-26 | Felman Daniel | Vertebral implant insertion process using shape memory material |
FR2728159B1 (en) | 1994-12-16 | 1997-06-27 | Tornier Sa | ELASTIC DISC PROSTHESIS |
US5665122A (en) | 1995-01-31 | 1997-09-09 | Kambin; Parviz | Expandable intervertebral cage and surgical method |
FR2730156B1 (en) | 1995-02-03 | 1997-04-30 | Textile Hi Tec | INTER SPINOUS HOLD |
FR2731643A1 (en) | 1995-03-16 | 1996-09-20 | Jbs Sa | Angular screwdriver for access of awkwardly placed screws for use in surgery |
US5690649A (en) | 1995-12-05 | 1997-11-25 | Li Medical Technologies, Inc. | Anchor and anchor installation tool and method |
US5702455A (en) | 1996-07-03 | 1997-12-30 | Saggar; Rahul | Expandable prosthesis for spinal fusion |
US5716416A (en) | 1996-09-10 | 1998-02-10 | Lin; Chih-I | Artificial intervertebral disk and method for implanting the same |
US5810815A (en) | 1996-09-20 | 1998-09-22 | Morales; Jose A. | Surgical apparatus for use in the treatment of spinal deformities |
US6190414B1 (en) | 1996-10-31 | 2001-02-20 | Surgical Dynamics Inc. | Apparatus for fusion of adjacent bone structures |
DE19652608C1 (en) | 1996-12-18 | 1998-08-27 | Eska Implants Gmbh & Co | Prophylaxis implant against fractures of osteoporotically affected bone segments |
US20020143331A1 (en) | 1998-10-20 | 2002-10-03 | Zucherman James F. | Inter-spinous process implant and method with deformable spacer |
US5836948A (en) | 1997-01-02 | 1998-11-17 | Saint Francis Medical Technologies, Llc | Spine distraction implant and method |
US6451019B1 (en) | 1998-10-20 | 2002-09-17 | St. Francis Medical Technologies, Inc. | Supplemental spine fixation device and method |
US6068630A (en) | 1997-01-02 | 2000-05-30 | St. Francis Medical Technologies, Inc. | Spine distraction implant |
US5860977A (en) | 1997-01-02 | 1999-01-19 | Saint Francis Medical Technologies, Llc | Spine distraction implant and method |
US7306628B2 (en) | 2002-10-29 | 2007-12-11 | St. Francis Medical Technologies | Interspinous process apparatus and method with a selectably expandable spacer |
US6712819B2 (en) | 1998-10-20 | 2004-03-30 | St. Francis Medical Technologies, Inc. | Mating insertion instruments for spinal implants and methods of use |
US7201751B2 (en) | 1997-01-02 | 2007-04-10 | St. Francis Medical Technologies, Inc. | Supplemental spine fixation device |
US6695842B2 (en) | 1997-10-27 | 2004-02-24 | St. Francis Medical Technologies, Inc. | Interspinous process distraction system and method with positionable wing and method |
US20070282443A1 (en) | 1997-03-07 | 2007-12-06 | Disc-O-Tech Medical Technologies Ltd. | Expandable element |
WO2001054598A1 (en) | 1998-03-06 | 2001-08-02 | Disc-O-Tech Medical Technologies, Ltd. | Expanding bone implants |
IL128261A0 (en) | 1999-01-27 | 1999-11-30 | Disc O Tech Medical Tech Ltd | Expandable element |
US6127597A (en) | 1997-03-07 | 2000-10-03 | Discotech N.V. | Systems for percutaneous bone and spinal stabilization, fixation and repair |
US6022376A (en) | 1997-06-06 | 2000-02-08 | Raymedica, Inc. | Percutaneous prosthetic spinal disc nucleus and method of manufacture |
CA2307888C (en) | 1997-10-27 | 2007-09-18 | Saint Francis Medical Technologies, Inc. | Spine distraction implant |
US6123731A (en) * | 1998-02-06 | 2000-09-26 | Osteotech, Inc. | Osteoimplant and method for its manufacture |
FR2774581B1 (en) | 1998-02-10 | 2000-08-11 | Dimso Sa | INTEREPINOUS STABILIZER TO BE ATTACHED TO SPINOUS APOPHYSIS OF TWO VERTEBRES |
FR2775183B1 (en) | 1998-02-20 | 2000-08-04 | Jean Taylor | INTER-SPINOUS PROSTHESIS |
US6126689A (en) | 1998-06-15 | 2000-10-03 | Expanding Concepts, L.L.C. | Collapsible and expandable interbody fusion device |
US6352537B1 (en) | 1998-09-17 | 2002-03-05 | Electro-Biology, Inc. | Method and apparatus for spinal fixation |
US6652527B2 (en) * | 1998-10-20 | 2003-11-25 | St. Francis Medical Technologies, Inc. | Supplemental spine fixation device and method |
US6554833B2 (en) | 1998-10-26 | 2003-04-29 | Expanding Orthopedics, Inc. | Expandable orthopedic device |
BR9805340B1 (en) | 1998-12-14 | 2009-01-13 | variable expansion insert for spinal stabilization. | |
US6206923B1 (en) | 1999-01-08 | 2001-03-27 | Sdgi Holdings, Inc. | Flexible implant using partially demineralized bone |
US6520991B2 (en) | 1999-05-11 | 2003-02-18 | Donald R. Huene | Expandable implant for inter-vertebral stabilization, and a method of stabilizing vertebrae |
US6214050B1 (en) | 1999-05-11 | 2001-04-10 | Donald R. Huene | Expandable implant for inter-bone stabilization and adapted to extrude osteogenic material, and a method of stabilizing bones while extruding osteogenic material |
US6419704B1 (en) | 1999-10-08 | 2002-07-16 | Bret Ferree | Artificial intervertebral disc replacement methods and apparatus |
JP4247519B2 (en) | 1999-08-18 | 2009-04-02 | イントリンジック セラピューティックス インコーポレイテッド | Apparatus and method for nucleus augmentation and retention |
FR2799640B1 (en) * | 1999-10-15 | 2002-01-25 | Spine Next Sa | IMPLANT INTERVETEBRAL |
US6520967B1 (en) | 1999-10-20 | 2003-02-18 | Cauthen Research Group, Inc. | Spinal implant insertion instrument for spinal interbody prostheses |
ATE294538T1 (en) | 1999-11-11 | 2005-05-15 | Synthes Ag | RADIALLY EXPANDABLE INTEGRAL NAIL |
US6293949B1 (en) | 2000-03-01 | 2001-09-25 | Sdgi Holdings, Inc. | Superelastic spinal stabilization system and method |
FR2806616B1 (en) | 2000-03-21 | 2003-04-11 | Cousin Biotech | INTERPINEUSE SHIM AND FASTENING DEVICE ON THE SACRUM |
US6402750B1 (en) | 2000-04-04 | 2002-06-11 | Spinlabs, Llc | Devices and methods for the treatment of spinal disorders |
US6645207B2 (en) | 2000-05-08 | 2003-11-11 | Robert A. Dixon | Method and apparatus for dynamized spinal stabilization |
FR2811540B1 (en) | 2000-07-12 | 2003-04-25 | Spine Next Sa | IMPORTING INTERVERTEBRAL IMPLANT |
US20020026244A1 (en) * | 2000-08-30 | 2002-02-28 | Trieu Hai H. | Intervertebral disc nucleus implants and methods |
CA2426932A1 (en) | 2000-10-25 | 2002-06-20 | Sdgi Holdings, Inc. | Vertically expanding intervertebral body fusion device |
US6582467B1 (en) | 2000-10-31 | 2003-06-24 | Vertelink Corporation | Expandable fusion cage |
FR2816197B1 (en) * | 2000-11-07 | 2003-01-10 | Jean Taylor | INTER-SPINABLE PROSTHESIS, TOOL AND PROCESS FOR PREPARING THE SAME |
US6666891B2 (en) | 2000-11-13 | 2003-12-23 | Frank H. Boehm, Jr. | Device and method for lumbar interbody fusion |
US6579319B2 (en) | 2000-11-29 | 2003-06-17 | Medicinelodge, Inc. | Facet joint replacement |
FR2818530B1 (en) | 2000-12-22 | 2003-10-31 | Spine Next Sa | INTERVERTEBRAL IMPLANT WITH DEFORMABLE SHIM |
GB0102141D0 (en) * | 2001-01-27 | 2001-03-14 | Davies John B C | Improvements in or relating to expandable bone nails |
WO2002065954A1 (en) | 2001-02-16 | 2002-08-29 | Queen's University At Kingston | Method and device for treating scoliosis |
US6364883B1 (en) | 2001-02-23 | 2002-04-02 | Albert N. Santilli | Spinous process clamp for spinal fusion and method of operation |
US6595998B2 (en) * | 2001-03-08 | 2003-07-22 | Spinewave, Inc. | Tissue distraction device |
FR2822051B1 (en) | 2001-03-13 | 2004-02-27 | Spine Next Sa | INTERVERTEBRAL IMPLANT WITH SELF-LOCKING ATTACHMENT |
US6582433B2 (en) | 2001-04-09 | 2003-06-24 | St. Francis Medical Technologies, Inc. | Spine fixation device and method |
US6527806B2 (en) | 2001-07-16 | 2003-03-04 | Third Millennium Engineering, Llc | Intervertebral spacer device having a spiral wave washer force restoring element |
US6375682B1 (en) | 2001-08-06 | 2002-04-23 | Lewis W. Fleischmann | Collapsible, rotatable and expandable spinal hydraulic prosthetic device |
FR2828398B1 (en) * | 2001-08-08 | 2003-09-19 | Jean Taylor | VERTEBRA STABILIZATION ASSEMBLY |
EP1418852A1 (en) | 2001-08-20 | 2004-05-19 | Synthes AG Chur | Interspinal prosthesis |
US6931259B2 (en) * | 2001-10-02 | 2005-08-16 | Agilnet Technologies, Inc. | Integrated circuit architecture for programmable wireless device |
FR2832917B1 (en) * | 2001-11-30 | 2004-09-24 | Spine Next Sa | ELASTICALLY DEFORMABLE INTERVERTEBRAL IMPLANT |
JP2005516648A (en) | 2001-12-13 | 2005-06-09 | エスディージーアイ・ホールディングス・インコーポレーテッド | Instruments and methods for introducing an implant into a vertebral space |
WO2003057055A1 (en) | 2001-12-27 | 2003-07-17 | Osteotech Inc. | Orthopedic/neurosurgical system and method for securing vertebral bone facets |
FR2835173B1 (en) * | 2002-01-28 | 2004-11-05 | Biomet Merck France | INTERTEPINEOUS VERTEBRAL IMPLANT |
US6733534B2 (en) * | 2002-01-29 | 2004-05-11 | Sdgi Holdings, Inc. | System and method for spine spacing |
US6923830B2 (en) | 2002-02-02 | 2005-08-02 | Gary K. Michelson | Spinal fusion implant having deployable bone engaging projections |
JP3708883B2 (en) * | 2002-02-08 | 2005-10-19 | 昭和医科工業株式会社 | Vertebral space retainer |
EP1346708A1 (en) | 2002-03-20 | 2003-09-24 | A-Spine Holding Group Corp. | Three-hooked device for fixing spinal column |
US7048736B2 (en) | 2002-05-17 | 2006-05-23 | Sdgi Holdings, Inc. | Device for fixation of spinous processes |
US20030220643A1 (en) | 2002-05-24 | 2003-11-27 | Ferree Bret A. | Devices to prevent spinal extension |
FR2844179B1 (en) * | 2002-09-10 | 2004-12-03 | Jean Taylor | POSTERIOR VERTEBRAL SUPPORT KIT |
US7833246B2 (en) * | 2002-10-29 | 2010-11-16 | Kyphon SÀRL | Interspinous process and sacrum implant and method |
US7749252B2 (en) | 2005-03-21 | 2010-07-06 | Kyphon Sarl | Interspinous process implant having deployable wing and method of implantation |
US20060064165A1 (en) * | 2004-09-23 | 2006-03-23 | St. Francis Medical Technologies, Inc. | Interspinous process implant including a binder and method of implantation |
US7549999B2 (en) * | 2003-05-22 | 2009-06-23 | Kyphon Sarl | Interspinous process distraction implant and method of implantation |
US6723126B1 (en) | 2002-11-01 | 2004-04-20 | Sdgi Holdings, Inc. | Laterally expandable cage |
US6685742B1 (en) | 2002-11-12 | 2004-02-03 | Roger P. Jackson | Articulated anterior expandable spinal fusion cage system |
CN1756517A (en) | 2002-11-21 | 2006-04-05 | Sdgi控股股份有限公司 | Systems and techniques for intravertebral spinal stablization with expandable devices |
WO2004047689A1 (en) | 2002-11-21 | 2004-06-10 | Sdgi Holdings, Inc. | Systems and techniques for intravertebral spinal stablization with expandable devices |
FR2851154B1 (en) | 2003-02-19 | 2006-07-07 | Sdgi Holding Inc | INTER-SPINOUS DEVICE FOR BRAKING THE MOVEMENTS OF TWO SUCCESSIVE VERTEBRATES, AND METHOD FOR MANUFACTURING THE SAME THEREOF |
ITFI20030084A1 (en) | 2003-03-28 | 2004-09-29 | Cousin Biotech S A S | INTERLAMINARY VERTEBRAL PROSTHESIS |
KR100582768B1 (en) | 2003-07-24 | 2006-05-23 | 최병관 | Insert complement for vertebra |
CN2638760Y (en) | 2003-08-04 | 2004-09-08 | 邹德威 | Dilator for forming cavity in pyramid |
EP1675513B8 (en) | 2003-10-24 | 2013-07-10 | Cousin Biotech, S.A.S. | Inter-blade support |
ES2287686T3 (en) | 2003-11-07 | 2007-12-16 | Impliant Ltd. | VERTEBRAL PROTESIS. |
AU2003304546A1 (en) | 2003-11-10 | 2005-06-08 | Umc Utrecht Holding B.V. | Expandable implant for treating fractured and/or collapsed bone |
US7217293B2 (en) | 2003-11-21 | 2007-05-15 | Warsaw Orthopedic, Inc. | Expandable spinal implant |
WO2005072301A2 (en) * | 2004-01-26 | 2005-08-11 | Reiley Mark A | Percutaneous spine distraction implant systems and methods |
US7641664B2 (en) * | 2004-02-12 | 2010-01-05 | Warsaw Orthopedic, Inc. | Surgical instrumentation and method for treatment of a spinal structure |
US8636802B2 (en) * | 2004-03-06 | 2014-01-28 | DePuy Synthes Products, LLC | Dynamized interspinal implant |
US7763073B2 (en) | 2004-03-09 | 2010-07-27 | Depuy Spine, Inc. | Posterior process dynamic spacer |
US7507241B2 (en) | 2004-04-05 | 2009-03-24 | Expanding Orthopedics Inc. | Expandable bone device |
US20080033552A1 (en) | 2004-05-17 | 2008-02-07 | Canon Kasushiki Kaisha | Sensor Device |
US7585316B2 (en) | 2004-05-21 | 2009-09-08 | Warsaw Orthopedic, Inc. | Interspinous spacer |
FR2871366A1 (en) * | 2004-06-09 | 2005-12-16 | Ceravic Soc Par Actions Simpli | PROSTHETIC EXPANSIBLE BONE IMPLANT |
US7776091B2 (en) * | 2004-06-30 | 2010-08-17 | Depuy Spine, Inc. | Adjustable posterior spinal column positioner |
US20060015181A1 (en) * | 2004-07-19 | 2006-01-19 | Biomet Merck France (50% Interest) | Interspinous vertebral implant |
US7951153B2 (en) * | 2004-10-05 | 2011-05-31 | Samy Abdou | Devices and methods for inter-vertebral orthopedic device placement |
US8162985B2 (en) * | 2004-10-20 | 2012-04-24 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
US9023084B2 (en) * | 2004-10-20 | 2015-05-05 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for stabilizing the motion or adjusting the position of the spine |
US8012207B2 (en) * | 2004-10-20 | 2011-09-06 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
US8317864B2 (en) * | 2004-10-20 | 2012-11-27 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
US8123807B2 (en) * | 2004-10-20 | 2012-02-28 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
US8167944B2 (en) * | 2004-10-20 | 2012-05-01 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
US20060089719A1 (en) * | 2004-10-21 | 2006-04-27 | Trieu Hai H | In situ formation of intervertebral disc implants |
CA2614133A1 (en) * | 2004-10-25 | 2006-05-04 | Lanx, Llc | Interspinous distraction devices and associated methods of insertion |
US7918875B2 (en) * | 2004-10-25 | 2011-04-05 | Lanx, Inc. | Interspinous distraction devices and associated methods of insertion |
US20060106381A1 (en) * | 2004-11-18 | 2006-05-18 | Ferree Bret A | Methods and apparatus for treating spinal stenosis |
US20060184248A1 (en) * | 2005-02-17 | 2006-08-17 | Edidin Avram A | Percutaneous spinal implants and methods |
US8038698B2 (en) * | 2005-02-17 | 2011-10-18 | Kphon Sarl | Percutaneous spinal implants and methods |
US20060195102A1 (en) * | 2005-02-17 | 2006-08-31 | Malandain Hugues F | Apparatus and method for treatment of spinal conditions |
US7837688B2 (en) | 2005-06-13 | 2010-11-23 | Globus Medical | Spinous process spacer |
US7383639B2 (en) * | 2005-07-12 | 2008-06-10 | Medtronic Spine Llc | Measurement instrument for percutaneous surgery |
AU2005336579A1 (en) | 2005-09-21 | 2007-03-29 | Sintea Biotech S.P.A. | Device, kit and method for intervertebral stabilization |
-
2004
- 2004-05-21 US US10/851,889 patent/US7585316B2/en active Active
-
2005
- 2005-05-04 CA CA002567403A patent/CA2567403A1/en not_active Abandoned
- 2005-05-04 WO PCT/US2005/015582 patent/WO2005115261A1/en active Application Filing
- 2005-05-04 JP JP2007527271A patent/JP4495218B2/en not_active Expired - Fee Related
- 2005-05-04 AU AU2005247335A patent/AU2005247335C1/en not_active Ceased
- 2005-05-04 EP EP05745238A patent/EP1765205B1/en not_active Not-in-force
- 2005-05-04 CN CN2005800162700A patent/CN1997320B/en not_active Expired - Fee Related
-
2009
- 2009-07-29 US US12/511,227 patent/US8216276B2/en active Active
-
2010
- 2010-03-04 JP JP2010047886A patent/JP4912480B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2005247335A1 (en) | 2005-12-08 |
CN1997320B (en) | 2011-11-09 |
US20050261768A1 (en) | 2005-11-24 |
EP1765205A1 (en) | 2007-03-28 |
US7585316B2 (en) | 2009-09-08 |
JP4912480B2 (en) | 2012-04-11 |
CN1997320A (en) | 2007-07-11 |
JP2008500129A (en) | 2008-01-10 |
US8216276B2 (en) | 2012-07-10 |
AU2005247335C1 (en) | 2009-11-05 |
WO2005115261A1 (en) | 2005-12-08 |
JP4495218B2 (en) | 2010-06-30 |
EP1765205B1 (en) | 2012-09-12 |
JP2010162358A (en) | 2010-07-29 |
US20090292315A1 (en) | 2009-11-26 |
AU2005247335B2 (en) | 2009-05-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2005247335B2 (en) | Interspinous spacer | |
US8252029B2 (en) | Expandable interspinous process spacer with lateral support and method for implantation | |
JP4852680B2 (en) | Intervertebral joint stabilization procedure | |
US7985246B2 (en) | Methods and instruments for delivering interspinous process spacers | |
US8177813B2 (en) | Expandable spinal spacer | |
US7261738B2 (en) | C-shaped disc prosthesis | |
US20090105773A1 (en) | Method and apparatus for insertion of an interspinous process device | |
US20160074086A1 (en) | Expandable Bone Implant | |
JP3224060U (en) | Spacer used for implanting in or between bones of an object, and implant component and implant system including the spacer | |
US20140379087A1 (en) | Cervical distraction method | |
US20080051896A1 (en) | Expandable Spinous Process Distractor | |
US20060084983A1 (en) | Systems and methods for posterior dynamic stabilization of the spine | |
JP2006515780A (en) | Artificial nucleus pulposus and injection method thereof | |
EP2608725A2 (en) | Intervertebral support | |
WO2020070697A1 (en) | Improved interlaminar-type intervertebral support device | |
JP2007537834A (en) | Functional spinal unit prosthesis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |