CN100567985C - 大肠癌标记物的检测方法 - Google Patents
大肠癌标记物的检测方法 Download PDFInfo
- Publication number
- CN100567985C CN100567985C CN03826172.3A CN03826172A CN100567985C CN 100567985 C CN100567985 C CN 100567985C CN 03826172 A CN03826172 A CN 03826172A CN 100567985 C CN100567985 C CN 100567985C
- Authority
- CN
- China
- Prior art keywords
- rna
- detection method
- colorectal cancer
- cdna
- tumor marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
Abstract
Description
Claims (4)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003075552 | 2003-03-19 | ||
JP75552/2003 | 2003-03-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1759317A CN1759317A (zh) | 2006-04-12 |
CN100567985C true CN100567985C (zh) | 2009-12-09 |
Family
ID=33027864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN03826172.3A Expired - Lifetime CN100567985C (zh) | 2003-03-19 | 2003-09-19 | 大肠癌标记物的检测方法 |
Country Status (10)
Country | Link |
---|---|
US (3) | US7816077B2 (zh) |
EP (1) | EP1605261B1 (zh) |
JP (2) | JP4134047B2 (zh) |
CN (1) | CN100567985C (zh) |
AT (1) | ATE451617T1 (zh) |
AU (1) | AU2003264512A1 (zh) |
CA (1) | CA2518933C (zh) |
DE (1) | DE60330505D1 (zh) |
ES (1) | ES2335344T3 (zh) |
WO (1) | WO2004083856A1 (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2335344T3 (es) * | 2003-03-19 | 2010-03-25 | Hamamatsu Foundation For Science And Technology Promotion | Procedimiento para detectar un marcador de cancer de colon. |
WO2007018257A1 (ja) | 2005-08-10 | 2007-02-15 | Hamamatsu Foundation For Science And Technology Promotion | 大腸癌マーカー検出方法 |
JP4477575B2 (ja) * | 2005-12-14 | 2010-06-09 | 株式会社日立製作所 | 大腸がんの検査に使用する遺伝子セット |
JPWO2008093530A1 (ja) * | 2007-01-30 | 2010-05-20 | 国立大学法人浜松医科大学 | 大腸癌病期検出方法 |
JP2009065900A (ja) * | 2007-09-13 | 2009-04-02 | Olympus Corp | 標的rnaの解析方法及び保存方法 |
JPWO2009057695A1 (ja) * | 2007-10-30 | 2011-03-10 | オリンパス株式会社 | 遺伝子解析による腺腫又はがんの検出方法 |
JP5616786B2 (ja) * | 2008-05-12 | 2014-10-29 | オリンパス株式会社 | 糞便処理容器 |
JP4538525B2 (ja) * | 2009-01-16 | 2010-09-08 | 千絵 宮本 | 癌関連遺伝子マーカーの検出方法 |
JP2011250757A (ja) * | 2010-06-03 | 2011-12-15 | Olympus Corp | 生体試料中の核酸検出方法 |
JPWO2012014694A1 (ja) * | 2010-07-26 | 2013-09-12 | オリンパス株式会社 | 糞便由来核酸の合成方法 |
GB201107466D0 (en) | 2011-05-05 | 2011-06-15 | Loktionov Alexandre | Device and method for non-invasive collection of colorectal mucocellular layer and disease detection |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4843155A (en) * | 1987-11-19 | 1989-06-27 | Piotr Chomczynski | Product and process for isolating RNA |
NL8900725A (nl) * | 1989-03-23 | 1990-10-16 | Az Univ Amsterdam | Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur. |
US5654179A (en) * | 1990-11-14 | 1997-08-05 | Hri Research, Inc. | Nucleic acid preparation methods |
US5777099A (en) * | 1995-02-24 | 1998-07-07 | Biotecx Laboratories, Inc. | RNA separation |
ES2347854T5 (es) * | 1996-03-26 | 2014-07-24 | Michael S. Kopreski | Método que permite el uso de RNA extracelular extraído de plasma o suero para detectar, monitorizar o evaluar un cáncer |
AU6951098A (en) * | 1997-04-04 | 1998-10-30 | The Texas A & M University System | Noninvasive detection of colonic biomarkers using fecal messenger rna |
US6406857B1 (en) * | 1997-06-16 | 2002-06-18 | Exact Sciences Corporation | Methods for stool sample preparation |
EP0939118A1 (en) * | 1998-02-20 | 1999-09-01 | Universiteit Maastricht | Method for isolating DNA and RNA from faeces |
US6335193B1 (en) | 1999-04-15 | 2002-01-01 | Padmanabhan P Nair | Isolated colonocytes |
JP2002142767A (ja) | 2000-11-06 | 2002-05-21 | Fujirebio Inc | 癌の検出方法及び癌化の進行の有無の判定方法 |
EP1373569A4 (en) * | 2001-03-02 | 2006-02-08 | Univ Pittsburgh | PCR METHOD |
AU2003239087A1 (en) * | 2002-06-25 | 2004-01-06 | Index Pharmaceuticals Ab | Method and kit for the diagnosis of ulcerative colitis |
ES2335344T3 (es) * | 2003-03-19 | 2010-03-25 | Hamamatsu Foundation For Science And Technology Promotion | Procedimiento para detectar un marcador de cancer de colon. |
JP3805330B2 (ja) | 2003-08-20 | 2006-08-02 | 独立行政法人科学技術振興機構 | 大腸癌及び大腸腺腫の検査方法 |
DE10345021A1 (de) * | 2003-09-23 | 2005-05-04 | Univ Potsdam | Verfahren zur nichtinvasiven Früherkennung von Dickdarmkrebs und/oder Darmkrebsvorläuferzellen |
WO2007018257A1 (ja) | 2005-08-10 | 2007-02-15 | Hamamatsu Foundation For Science And Technology Promotion | 大腸癌マーカー検出方法 |
US7939255B2 (en) * | 2006-07-03 | 2011-05-10 | Catholic University Industry Academy Cooperation Foundation | Diagnostic methods for colorectal cancer |
-
2003
- 2003-09-19 ES ES03816367T patent/ES2335344T3/es not_active Expired - Lifetime
- 2003-09-19 DE DE60330505T patent/DE60330505D1/de not_active Expired - Lifetime
- 2003-09-19 CA CA2518933A patent/CA2518933C/en not_active Expired - Fee Related
- 2003-09-19 EP EP03816367A patent/EP1605261B1/en not_active Expired - Lifetime
- 2003-09-19 US US10/549,389 patent/US7816077B2/en not_active Expired - Lifetime
- 2003-09-19 AU AU2003264512A patent/AU2003264512A1/en not_active Abandoned
- 2003-09-19 CN CN03826172.3A patent/CN100567985C/zh not_active Expired - Lifetime
- 2003-09-19 AT AT03816367T patent/ATE451617T1/de not_active IP Right Cessation
- 2003-09-19 WO PCT/JP2003/011972 patent/WO2004083856A1/ja active Application Filing
- 2003-09-19 JP JP2004569601A patent/JP4134047B2/ja not_active Expired - Lifetime
-
2008
- 2008-04-21 JP JP2008109891A patent/JP4206425B2/ja not_active Expired - Lifetime
-
2009
- 2009-07-14 US US12/460,143 patent/US8080378B2/en not_active Expired - Lifetime
-
2010
- 2010-09-03 US US12/875,207 patent/US8445202B2/en not_active Expired - Fee Related
Non-Patent Citations (10)
Title |
---|
. 吉田功等.日本消化器并学会杂志,第99卷第临时增刊期. 2002 |
Abnormal expression of CD44 variants in the exfoliated cells inthe feces of patients with colorectal cancer. Takekazu Yamao et al.Gastroenterology,Vol.114 No.6. 1998 |
Abnormal expression of CD44 variants in the exfoliated cells inthe feces of patients with colorectal cancer. Takekazu Yamao et al.Gastroenterology,Vol.114 No.6. 1998 * |
Bio Jikken Illustrated 2 Idenshi Kaiseki no Kiso. Hiroki Nakagawa,153-166,Shujunsha Co., Ltd.. 1995 |
Expression of cyclooxygenase-1 and -2 in human colorectalcancer. Hajime Sano et al.Cancer Research,Vol.55 No.17. 1995 |
Expression of cyclooxygenase-1 and-2 in human colorectalcancer. Hajime Sano et al.Cancer Research,Vol.55 No.17. 1995 * |
Non-invasive detectionof fecal protein kinase C βII and ξmessenger RNA: putative biomarkers for colon cancer. Laurie A. Davidson et al.Carcinogenesis,Vol.19 No.2. 1998 |
Purificationof total RNA from human stool samples. Richard J. Alexander et al.Digestive Disease and Science,Vol.43 No.12. 1998 |
吉田功等.日本消化器并学会杂志,第99卷第临时增刊期. 2002 * |
大肠癌胃泌素mRNA表达的临床研究. 方胜等.皖南医学院学报,第21卷第1期. 2002 |
Also Published As
Publication number | Publication date |
---|---|
EP1605261A4 (en) | 2007-08-29 |
ES2335344T3 (es) | 2010-03-25 |
US7816077B2 (en) | 2010-10-19 |
CA2518933A1 (en) | 2004-09-30 |
CA2518933C (en) | 2012-04-03 |
CN1759317A (zh) | 2006-04-12 |
EP1605261B1 (en) | 2009-12-09 |
JP2008271969A (ja) | 2008-11-13 |
US8445202B2 (en) | 2013-05-21 |
DE60330505D1 (de) | 2010-01-21 |
JP4206425B2 (ja) | 2009-01-14 |
AU2003264512A1 (en) | 2004-10-11 |
US20060216714A1 (en) | 2006-09-28 |
US20090291447A1 (en) | 2009-11-26 |
WO2004083856A1 (ja) | 2004-09-30 |
EP1605261A1 (en) | 2005-12-14 |
ATE451617T1 (de) | 2009-12-15 |
US20100323367A1 (en) | 2010-12-23 |
US8080378B2 (en) | 2011-12-20 |
JP4134047B2 (ja) | 2008-08-13 |
JPWO2004083856A1 (ja) | 2006-06-22 |
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