CN101065080A - 用于处理骨和其他组织的方法、材料和器械 - Google Patents
用于处理骨和其他组织的方法、材料和器械 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7094—Solid vertebral fillers; devices for inserting such fillers
- A61B17/7095—Solid vertebral fillers; devices for inserting such fillers the filler comprising unlinked macroscopic particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
- A61B17/8811—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by the introducer tip, i.e. the part inserted into or onto the bone
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- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
- A61B17/8816—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by the conduit, e.g. tube, along which fluid flows into the body or by conduit connections
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- A—HUMAN NECESSITIES
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- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
- A61B17/8822—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum
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- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
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- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/885—Tools for expanding or compacting bones or discs or cavities therein
- A61B17/8852—Tools for expanding or compacting bones or discs or cavities therein capable of being assembled or enlarged, or changing shape, inside the bone or disc
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- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01F27/05—Stirrers
- B01F27/11—Stirrers characterised by the configuration of the stirrers
- B01F27/114—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections
- B01F27/1143—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections screw-shaped, e.g. worms
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/86—Mixing heads comprising a driven stirrer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/10—Maintenance of mixers
- B01F35/12—Maintenance of mixers using mechanical means
- B01F35/123—Maintenance of mixers using mechanical means using scrapers for cleaning mixers
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/50—Mixing receptacles
- B01F35/53—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
- B01F35/531—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components with baffles, plates or bars on the wall or the bottom
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/75—Discharge mechanisms
- B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
- B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
- B01F35/754251—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers reciprocating in the mixing receptacle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
- A61B17/8819—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by the introducer proximal part, e.g. cannula handle, or by parts which are inserted inside each other, e.g. stylet and cannula
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- A61B2017/00535—Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
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- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
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- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
Abstract
Description
共聚物(MA∶LMA) | MA(ml/mol) | LMA(ml/mol) | BPO(mg/mol) | THF(ml) |
100∶080∶2070∶3060∶4050∶5040∶6030∶7020∶800∶100 | 100(0.94)80(0.75)70(0.66)60(0.56)50(0.47)40(0.38)30(0.28)20(0.19)0(0) | 0(0)20(0.07)30(0.10)40(0.14)50(0.17)60(0.20)70(0.24)80(0.27)100(0.34) | 285(1.18)258(1.06)239(0.99)220(0.9)201(0.83)182(0.75)163(0.67)144(0.6)107(0.44) | 100100100100100100100100100 |
给料比MMA∶LMA | NMR分析 | 聚合物的GPC分析 | |||
体积%(摩尔%) | [MMA]∶[LMA] | Mn | Mw | 多分散性 | [η] |
100∶0(100∶0)8∶2(91.5∶8.5)7∶3(87∶13)6∶4(84∶16)1∶1(74∶26)4∶5(69∶31)4∶6(64∶36)3∶7(56∶44)2∶8(40∶60)0∶100(0∶100) | 100∶0[88]∶[12]87∶1384∶1669∶3170∶3062∶3856∶4440∶600∶100 | 65190691186300673295941675545575648351032387627350 | 119544119194112442118384135880104711134745799866872075146 | 1.8331.7241.781.6151.441.8881.7812.272.872.74 | 0.5440.4210.3930.3660.3510.3160.3050.2210.1780.083 |
组合物 MA∶LA(体积%) | 最大强度(Mpa) | 模量(Mpa) |
1∶08∶27∶36∶45∶54∶63∶72∶8 | 106.8(9)82.5(17.1)63.3(13.2)48(11)18.9(4.5)1.9(0.2)19.19(3.42)0.253(0.06) | 2478(220)1100.7(129)634.5(116)550(250)69.6(20)49.5(11.8)8.3(1.2)1.71(0.417) |
Claims (66)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710017544.2A CN106963464B (zh) | 2004-07-30 | 2005-07-31 | 外科用具 |
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59214904P | 2004-07-30 | 2004-07-30 | |
US60/592,149 | 2004-07-30 | ||
IL16601704A IL166017A0 (en) | 2004-12-28 | 2004-12-28 | Materials devices and methods for treating bones |
IL166017 | 2004-12-28 | ||
US64778405P | 2005-01-31 | 2005-01-31 | |
US60/647,784 | 2005-01-31 | ||
US65449505P | 2005-02-22 | 2005-02-22 | |
US60/654,495 | 2005-02-22 | ||
PCT/IL2005/000812 WO2006011152A2 (en) | 2004-06-17 | 2005-07-31 | Methods for treating bone and other tissue |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201710017544.2A Division CN106963464B (zh) | 2004-07-30 | 2005-07-31 | 外科用具 |
Publications (2)
Publication Number | Publication Date |
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CN101065080A true CN101065080A (zh) | 2007-10-31 |
CN101065080B CN101065080B (zh) | 2021-10-29 |
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ID=37913514
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CN200580031798.5A Active CN101065080B (zh) | 2004-07-30 | 2005-07-31 | 用于处理骨和其他组织的材料和器械 |
CN201710017544.2A Active CN106963464B (zh) | 2004-07-30 | 2005-07-31 | 外科用具 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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CN201710017544.2A Active CN106963464B (zh) | 2004-07-30 | 2005-07-31 | 外科用具 |
Country Status (6)
Country | Link |
---|---|
US (5) | US10039585B2 (zh) |
EP (1) | EP1786343B1 (zh) |
CN (2) | CN101065080B (zh) |
CA (1) | CA2575699C (zh) |
IL (1) | IL181072A0 (zh) |
WO (1) | WO2006011152A2 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102665797A (zh) * | 2009-10-19 | 2012-09-12 | 药物代谢动力公司 | 用于向椎间盘和脊椎供给生物制剂的远程致动压电泵 |
CN113558740A (zh) * | 2021-08-04 | 2021-10-29 | 西安市红会医院 | 一种椎体成型用骨水泥自搅拌用推送器 |
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US7621950B1 (en) | 1999-01-27 | 2009-11-24 | Kyphon Sarl | Expandable intervertebral spacer |
DE10032220A1 (de) * | 2000-07-03 | 2002-01-24 | Sanatis Gmbh | Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung |
US6632235B2 (en) * | 2001-04-19 | 2003-10-14 | Synthes (U.S.A.) | Inflatable device and method for reducing fractures in bone and in treating the spine |
CN1835720B (zh) * | 2001-07-25 | 2011-09-28 | Disc整形外科技术股份有限公司 | 可变形工具及植入物 |
US20030055316A1 (en) * | 2001-09-19 | 2003-03-20 | Brannon James Kevin | Endoscopic bone debridement |
DE10154163A1 (de) | 2001-11-03 | 2003-05-22 | Advanced Med Tech | Vorrichtung zum Aufrichten und Stabilisieren der Wirbelsäule |
US7273523B2 (en) * | 2002-06-07 | 2007-09-25 | Kyphon Inc. | Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof |
WO2004019815A2 (en) * | 2002-08-27 | 2004-03-11 | Sdgi Holdings, Inc. | Systems and methods for intravertebral reduction |
US20060264967A1 (en) | 2003-03-14 | 2006-11-23 | Ferreyro Roque H | Hydraulic device for the injection of bone cement in percutaneous vertebroplasty |
US8066713B2 (en) | 2003-03-31 | 2011-11-29 | Depuy Spine, Inc. | Remotely-activated vertebroplasty injection device |
TWI235055B (en) * | 2003-05-21 | 2005-07-01 | Guan-Gu Lin | Filling device capable of removing animal tissues |
TW587932B (en) * | 2003-05-21 | 2004-05-21 | Guan-Gu Lin | Removable animal tissue filling device |
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US8415407B2 (en) | 2004-03-21 | 2013-04-09 | Depuy Spine, Inc. | Methods, materials, and apparatus for treating bone and other tissue |
WO2006011152A2 (en) | 2004-06-17 | 2006-02-02 | Disc-O-Tech Medical Technologies, Ltd. | Methods for treating bone and other tissue |
US8062270B2 (en) * | 2003-07-15 | 2011-11-22 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US9326806B2 (en) * | 2003-09-02 | 2016-05-03 | Crosstrees Medical, Inc. | Devices and methods for the treatment of bone fracture |
WO2005030034A2 (en) | 2003-09-26 | 2005-04-07 | Depuy Spine, Inc. | Device for delivering viscous material |
TW200511970A (en) * | 2003-09-29 | 2005-04-01 | Kwan-Ku Lin | A spine wrapping and filling apparatus |
ES2396133T3 (es) | 2004-04-27 | 2013-02-19 | Kyphon SÀRl | Composiciones de sustitución osea y método de uso |
US20080132899A1 (en) * | 2004-05-17 | 2008-06-05 | Shadduck John H | Composite implant and method for treating bone abnormalities |
US7749268B2 (en) * | 2004-05-26 | 2010-07-06 | Warsaw Orthopedic, Inc. | Methods for treating the spine |
US7621952B2 (en) * | 2004-06-07 | 2009-11-24 | Dfine, Inc. | Implants and methods for treating bone |
US20060085081A1 (en) * | 2004-06-07 | 2006-04-20 | Shadduck John H | Implants and methods for treating bone |
US20060095138A1 (en) * | 2004-06-09 | 2006-05-04 | Csaba Truckai | Composites and methods for treating bone |
US20060085009A1 (en) * | 2004-08-09 | 2006-04-20 | Csaba Truckai | Implants and methods for treating bone |
CN101257864A (zh) * | 2004-09-02 | 2008-09-03 | 十字桅杆药品公司 | 脊椎盘腔牵引用的设备和方法 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102665797A (zh) * | 2009-10-19 | 2012-09-12 | 药物代谢动力公司 | 用于向椎间盘和脊椎供给生物制剂的远程致动压电泵 |
CN102665797B (zh) * | 2009-10-19 | 2014-06-18 | 药物代谢动力公司 | 用于向椎间盘和脊椎供给生物制剂的远程致动压电泵 |
CN113558740A (zh) * | 2021-08-04 | 2021-10-29 | 西安市红会医院 | 一种椎体成型用骨水泥自搅拌用推送器 |
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US8956368B2 (en) | 2015-02-17 |
CA2575699C (en) | 2014-07-08 |
EP1786343A2 (en) | 2007-05-23 |
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US20090264942A1 (en) | 2009-10-22 |
CN106963464A (zh) | 2017-07-21 |
IL181072A0 (en) | 2008-04-13 |
US20090264892A1 (en) | 2009-10-22 |
US20060079905A1 (en) | 2006-04-13 |
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EP1786343B1 (en) | 2012-05-02 |
WO2006011152A3 (en) | 2007-05-24 |
EP1786343A4 (en) | 2008-10-15 |
US8540722B2 (en) | 2013-09-24 |
WO2006011152A2 (en) | 2006-02-02 |
CN106963464B (zh) | 2019-11-05 |
US20150127058A1 (en) | 2015-05-07 |
US9504508B2 (en) | 2016-11-29 |
CA2575699A1 (en) | 2006-02-02 |
CN101065080B (zh) | 2021-10-29 |
US10039585B2 (en) | 2018-08-07 |
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