CN102175982A - Superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI) - Google Patents
Superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI) Download PDFInfo
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- CN102175982A CN102175982A CN2011100340141A CN201110034014A CN102175982A CN 102175982 A CN102175982 A CN 102175982A CN 2011100340141 A CN2011100340141 A CN 2011100340141A CN 201110034014 A CN201110034014 A CN 201110034014A CN 102175982 A CN102175982 A CN 102175982A
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Abstract
The invention relates to a superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI). The SQUID cooling device comprises a cooling head and a cooling conduit, wherein the cooling head is connected with an external cooling device through the cooling conduit. Ultra low temperature suitable for the operation of an SQUID is acquired through a cold supply device and transmitted to the SQUID through the cooling conduit and the cooling head so as to provide an ultra low temperature working environment for the SQUID; because only the cooling head and partial cooling conduit need to be encapsulated, liquid helium and liquid nitrogen are not needed; because only the cooling head and the cooling conduit need to be encapsulated, the cooling device has simple and practical structure, and saves the operation and maintenance costs; and the device is suitable to be used as the cooling device for the SQUID of the handheld ultra low field MRI. A cooling capsule is arranged, and one of the cooling capsule and an external refrigerating device can be selectively used; under the condition that the external refrigerating device is started, the used cooling capsule can be inserted into the installation cavity of the cooling capsule; and through the external refrigerating device, the coolant in the cooling capsule is newly liquefied, so that the cooling capsule can be recycled.
Description
Technical field
The present invention relates to a kind of cooling device, relate in particular to the SQUID cooling device of the ultralow field MRI of a kind of hand-held.
Background technology
Existing MRI (Magnetic Resonance Imaging, magnetic resonance imaging), its hardware device mainly comprises computing machine, magnet (or polarizing coil), gradient coil, drive coil, magnetic flux probe, receiving coil, data acquisition module, main control module, electric power control module and interface module.Wherein, drive coil is placed on the position near testee, is used to produce the pumping signal to tested object different parts; Magnet (or polarizing coil) and gradient coil be evenly arranged in testee around, be used for the magnetic field of generation rule; The electric power control module all is electrically connected with data acquisition module, main control module and magnetic flux probe; Receiving coil is used to receive the magnetic resonance signal of testee, the output terminal of receiving coil is connected with the input end of magnetic flux probe, the output terminal of magnetic flux probe is connected with the input end of data acquisition module, the output terminal of data acquisition module is connected with the input end of main control module, the output terminal of main control module is connected with interface module, and interface module is connected with computing machine.Magnetic field by polarizing coil and gradient coil generation rule, make the atomic polarization in the testee, by regularly arranged, by drive coil testee is sent pumping signal again, make atom generation spin regularly arranged in the testee and send magnetic resonance signal, after magnetic resonance signal is received by receiving coil, be converted into electric signal through the magnetic flux probe, and, adopt imaging formula on computers by sending computing machine to after the foregoing circuit resume module, rebuild the image of testee.MRI mainly contains permanent-magnet type and superconduct in clinical practice:
Permanent-magnet type MRI price is lower, can reach the effect of clinical examination, but volume weight is huge, and magnet wherein needs a large amount of expensive rare earth materials that adopt.
Superconduct MRI, be the best mr imaging technique of performance at present, but because its magnetic flux detecting head has adopted the superconducting magnet material that need could work under ultralow temperature, need be operated under the ultra-low temperature surroundings, routine work, maintenance need a large amount of expensive liquid helium cold-producing mediums that use, volume is also very huge, is not suitable for purchasing and middle and small hospital that daily budget is few.
This shows that existing permanent-magnet type MRI and superconduct MRI structure are all huger, are not suitable for doing portable equipment, and need be in the indoor operation of electromagnetic screen.
SQUID (Superconducting Quantum Interference Device, superconducting quantum interference device) as the present the highest magnetic flux detector of sensitivity in the world, volume is very little, be suitable for making the ultralow field MRI of hand-held system, but at present owing to still need to adopt liquid helium SQUID to be cooled off as the cold-producing medium refrigeration, its cooling structure is huger, can't be packaged together with SQUID, this is to cause can't adopting at present SQUID to make a major reason of the ultralow field MRI of hand-held, therefore, also do not occur utilizing SQUID to make the ultralow field MRI of hand-held system at present as core component.And long-term a large amount of use liquid helium or liquid nitrogen cools off SQUID, and this class cold-producing medium belongs to non-renewable scarce resource, costs an arm and a leg.
Summary of the invention
Technical matters to be solved by this invention provides the SQUID cooling device of the ultralow field MRI of a kind of hand-held, the SQUID cooling device of the ultralow field MRI of this hand-held is simple in structure, and volume is little, is suitable as the cooling of the SQUID of the ultralow field MRI of hand-held, good cooling results, and save cost.The technical scheme that adopts is as follows:
The SQUID cooling device of the ultralow field MRI of a kind of hand-held is characterized in that: comprise refrigerating head, cooling duct and cooling apparatus, refrigerating head contacts with SQUID, and refrigerating head is connected with cooling apparatus by cooling duct.
The basic demand that constitutes hand-held MRI is that polarizing coil module, gradient coil module, receiving coil module, cooling device and SQUID all are encapsulated in the probing shell the inside, yet, adopt the type of cooling of liquid helium, liquid nitrogen obviously not meet the requirement that is packaged together at present.The present invention obtains to be suitable for the ultralow temperature of SQUID work by cooling apparatus, and conduct to SQUID by cooling duct and refrigerating head, for SQUID provides the ultralow temperature working environment, needing the part of encapsulation is refrigerating head and part cooling duct, under the less situation of cooling apparatus volume, can also be encapsulated in cooling apparatus in the probing shell in the lump, make the hand-held degree higher, realize simple, so being suitable as the refrigerating plant of hand-held MRI uses, and need not to adopt the liquid helium cooling, saving work, maintenance cost, simple and practical.
In order to reach purpose simple in structure, as preferred version of the present invention, it is characterized in that: described cooling apparatus comprises the external refrigeration device, and the external refrigeration device is connected with cooling duct.Freeze by existing external refrigeration device, need be encapsulated in the just refrigerating head and the part cooling duct of probing shell the inside, simple in structure.The said external refrigerating plant can adopt the UP series etc. of the Thales Cryogenics company in the PT405 of U.S. Cryomech company or Europe, and this two super low temperature refrigeration device is well suited for providing for SQUID the working environment of ultralow temperature.
In order to reach purpose easy to use, as another kind of preferred version of the present invention, it is characterized in that: described cooling apparatus comprises cooling capsule installation cavity and cooling capsule; The cooling capsule comprises capsule interface module module, cooling medium inlet valve, capsule cavity and cooling medium delivery outlet valve, and the capsule cavity is provided with heat insulation layer, and cooling medium inlet valve and coolant outlet valve are divided into capsule cavity two ends; Cooling medium inlet valve is connected with the main control module by the capsule interface module with the coolant outlet valve; The cooling capsule is in the cooling capsule installation cavity, and cooling medium delivery outlet valve is connected with cooling duct.The capsule interface module is connected with the main control module of MRI, accepts the instruction of main control module, makes cooling medium inlet valve and coolant outlet valve closing or unlatching.Can inject cooling mediums such as liquid helium, liquid nitrogen in the capsule cavity by cooling medium inlet valve, discharging cooling medium by cooling medium delivery outlet valve is the SQUID cooling through refrigerating head.To cool off capsule and make plug-in with cooling capsule installation cavity, the cooling capsule that will be full of cooling medium inserts in the cooling capsule installation cavity, discharging cooling medium by the cooling capsule is the SQUID cooling, the cooling medium that injects the cooling capsule maintains can expire Polaroid dosage and be as the criterion, therefore cooling off capsule can do very for a short time, can all be encapsulated in the probing shell the inside, easy to use, be more suitable for the hand-held requirement of MRI system; The cooling capsule by the external refrigeration device, liquefies the cooling medium in the cooling capsule again, thereby the cooling capsule can be recycled losing under the situation of cooling effect.
In order to reach the purpose of conveniently using and recycling, as another kind of preferred version of the present invention, it is characterized in that: described cooling apparatus comprises external refrigeration device, cooling capsule installation cavity and cooling capsule; The external refrigeration device is connected with cooling duct; The cooling capsule comprises capsule interface module, cooling medium inlet valve, capsule cavity and cooling medium delivery outlet valve, and the capsule cavity is provided with heat insulation layer, and cooling medium inlet valve and coolant outlet valve are divided into capsule cavity two ends; Cooling medium inlet valve is connected with the main control module by the capsule interface module with the coolant outlet valve; The cooling capsule is in the cooling capsule installation cavity, and cooling medium delivery outlet valve is connected with cooling duct.Under the situation of not opening the external refrigeration device, the cooling capsule that is full of cooling medium can be inserted in the cooling capsule installation cavity, discharging cooling medium by the cooling capsule is the SQUID cooling, the cooling medium that injects the cooling capsule maintains can expire Polaroid dosage and be as the criterion, therefore cooling off capsule can do very for a short time, is more suitable for the hand-held requirement of MRI system; And under the situation of not using the cooling of cooling capsule, can cool off by external refrigeration device, cooling duct and refrigerating head; Externally under the situation that refrigerating plant is opened, used cooling capsule (having lost cooling effect) can be inserted in the cooling capsule installation cavity, by the external refrigeration device, the cooling medium in the cooling capsule is liquefied again, thereby the cooling capsule can be recycled.
The SQUID cooling device of the ultralow field MRI of hand-held of the present invention obtains to be suitable for the ultralow temperature of SQUID work by cooling apparatus, and conduct to SQUID by cooling duct and refrigerating head, for SQUID provides the ultralow temperature working environment, needing the part of encapsulation is refrigerating head and part cooling duct, simple in structure, practical, saving work, safeguard maintenance cost, be suitable as the cooling device of the SQUID of the ultralow field MRI of hand-held.By the cooling capsule is set, and the minimum cryogen consumption, under the situation of not opening the external refrigeration device, discharging cooling medium by the cooling capsule is the SQUID cooling, the cooling capsule can be done very for a short time, is more suitable for the hand-held requirement of MRI system; And do not using under the anxious situation about lacking of cooling of cooling capsule or cooling medium, can cool off by external refrigeration device, cooling duct and refrigerating head, externally under the situation that refrigerating plant is opened, used cooling capsule (having lost cooling effect) can be inserted in the cooling capsule installation cavity, by the external refrigeration device, cooling medium in the cooling capsule is liquefied again, thereby the cooling capsule can be recycled.
Description of drawings
Fig. 1 is the structural representation of the preferred embodiment for the present invention one
Fig. 2 is the structural representation of cooling capsule in the preferred embodiment for the present invention one
Fig. 3 is the structural representation of the preferred embodiment for the present invention two
Fig. 4 is the structural representation of the preferred embodiment for the present invention three
Embodiment
Be described further below in conjunction with accompanying drawing and preferred implementation of the present invention.
Embodiment one
As depicted in figs. 1 and 2, the SQUID cooling device of the ultralow field MRI of this hand-held comprises refrigerating head 1, cooling duct 2, external refrigeration device 3, cooling capsule installation cavity 4 and cooling capsule 5; Refrigerating head 1 is connected with external refrigeration device 3 by cooling duct 2; Cooling capsule 5 comprises capsule interface module 6, cooling medium inlet valve 7, capsule cavity 8 and cooling medium delivery outlet valve 9, and capsule cavity 8 is provided with heat insulation layer, and cooling medium inlet valve 7 and coolant outlet valve 9 are divided into capsule cavity 8 two ends; Capsule interface module 6 is connected with coolant outlet valve 9 with cooling medium inlet valve 7; Cooling capsule 5 is in the cooling capsule installation cavity 4, and cooling medium delivery outlet valve 9 is connected with cooling duct 2, and cooling duct 2 is connected with refrigerating head 1.
During installation, to cool off capsule 5 and insert in the capsule installation cavity 4, capsule interface module 6 is connected with the main control module 10 of MRI, accepts the instruction of main control module 10, make cooling medium inlet valve 7 and coolant outlet valve 9 close or open, refrigerating head 1 contacts with SQUID11.
By utilizing external refrigeration device 3 (existing refrigerating plant) to freeze, and give refrigerating head 1, SQUID11 is cooled off, need not to use liquid helium, liquid nitrogen by cooling duct 2 conduction; Under the situation of not opening external refrigeration device 3, discharging cooling medium by cooling capsule 5 is the SQUID11 cooling, and cooling capsule 5 can be done very for a short time, is more suitable for the hand-held requirement of MRI system; And do not using under 5 coolings of cooling capsule or the anxious situation about lacking of cooling medium, can cool off by external refrigeration device 3, cooling duct 2 and refrigerating head 1, externally under the situation that refrigerating plant 3 is opened, used cooling capsule 5 (having lost cooling effect) can be inserted in the cooling capsule installation cavity 4, by external refrigeration device 3, cooling medium in the cooling capsule 5 is liquefied again, thereby cooling capsule 5 can be recycled.
The UP ultralow temperature refrigeratory of the PT405 that preferred said external refrigerating plant is a U.S. Cryomech company or the Thales Cryogenics company in Europe.
Embodiment two
As shown in Figure 3, the SQUID cooling device of the ultralow field MRI of this hand-held only comprises refrigerating head 1, cooling duct 2 and external refrigeration device 3.
Embodiment three
As shown in Figure 4, the SQUID cooling device of the ultralow field MRI of this hand-held only comprises refrigerating head 1, cooling duct 2, cooling capsule installation cavity 4 and cooling capsule 5.
Claims (4)
1. the SQUID cooling device of the ultralow field MRI of hand-held, it is characterized in that: comprise refrigerating head, cooling duct and cooling apparatus, refrigerating head contacts with SQUID, and refrigerating head is connected with cooling apparatus by cooling duct.
2. SQUID cooling device as claimed in claim 1 is characterized in that: described cooling apparatus comprises the external refrigeration device, and the external refrigeration device is connected with cooling duct.
3. SQUID cooling device as claimed in claim 1 is characterized in that: described cooling apparatus comprises cooling capsule installation cavity and cooling capsule; The cooling capsule comprises capsule interface module module, cooling medium inlet valve, capsule cavity and cooling medium delivery outlet valve, and the capsule cavity is provided with heat insulation layer, and cooling medium inlet valve and coolant outlet valve are divided into capsule cavity two ends; Cooling medium inlet valve is connected with the main control module by the capsule interface module with the coolant outlet valve; The cooling capsule is in the cooling capsule installation cavity, and cooling medium delivery outlet valve is connected with cooling duct.
4. SQUID cooling device as claimed in claim 1 is characterized in that: described cooling apparatus comprises external refrigeration device, cooling capsule installation cavity and cooling capsule; The external refrigeration device is connected with cooling duct; The cooling capsule comprises capsule interface module, cooling medium inlet valve, capsule cavity and cooling medium delivery outlet valve, and the capsule cavity is provided with heat insulation layer, and cooling medium inlet valve and coolant outlet valve are divided into capsule cavity two ends; Cooling medium inlet valve is connected with the main control module by the capsule interface module with the coolant outlet valve; The cooling capsule is in the cooling capsule installation cavity, and cooling medium delivery outlet valve is connected with cooling duct.
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| CN 201110034014 CN102175982B (en) | 2011-01-31 | 2011-01-31 | Superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI) |
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| CN 201110034014 CN102175982B (en) | 2011-01-31 | 2011-01-31 | Superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110888096A (en) * | 2018-09-10 | 2020-03-17 | 通用电气公司 | System and method for thermal management of cryocooler |
Citations (4)
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| CN2566196Y (en) * | 2002-07-09 | 2003-08-13 | 中国科学院理化技术研究所 | Non-magnetic low vibration coaxial pulse pipe refrigerator |
| CN1467461A (en) * | 2002-07-09 | 2004-01-14 | 中国科学院理化技术研究所 | Nonmagnetic low-vibration coaxial impulse pipe refrigerating machine |
| CN1595675A (en) * | 2004-06-23 | 2005-03-16 | 华中科技大学 | A cooling arrangement for high temperature superconducting device |
| US20090072828A1 (en) * | 2007-05-04 | 2009-03-19 | Penanen Konstantin I | Low field squid mri devices, components and methods |
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2011
- 2011-01-31 CN CN 201110034014 patent/CN102175982B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2566196Y (en) * | 2002-07-09 | 2003-08-13 | 中国科学院理化技术研究所 | Non-magnetic low vibration coaxial pulse pipe refrigerator |
| CN1467461A (en) * | 2002-07-09 | 2004-01-14 | 中国科学院理化技术研究所 | Nonmagnetic low-vibration coaxial impulse pipe refrigerating machine |
| CN1595675A (en) * | 2004-06-23 | 2005-03-16 | 华中科技大学 | A cooling arrangement for high temperature superconducting device |
| US20090072828A1 (en) * | 2007-05-04 | 2009-03-19 | Penanen Konstantin I | Low field squid mri devices, components and methods |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110888096A (en) * | 2018-09-10 | 2020-03-17 | 通用电气公司 | System and method for thermal management of cryocooler |
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Owner name: SHANTOU DONGFANG ULTRASONIC TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: SHANTOU INSTITUTE OF ULTRASONIC INSTRUMENTS CO., LTD. Effective date: 20140702 |
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Effective date of registration: 20140702 Address after: 515041 Guangdong, Shantou Jinsha Road, No. 1, building 77 Patentee after: Shantou Dongfang Ultrasonic Technology Co.,Ltd. Address before: 515041 No. 77 Jinsha Road, Jinping District, Guangdong, Shantou Patentee before: Shantou Institute of Ultrasonic Instruments Co., Ltd. |
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Address after: 515041 Guangdong City, Longhu Province Wan Industrial Zone, Longjiang Road, Mount Everest road and the junction of the northwest side of the area, building 2, on the east side of the East Patentee after: Shantou Ultrasonic Testing Technology Co., Ltd. Address before: 515041 Guangdong, Shantou Jinsha Road, No. 1, building 77 Patentee before: Shantou Dongfang Ultrasonic Technology Co.,Ltd. |