CN102589700A - Optical fiber detecting probe head for portable raman spectrometer - Google Patents
Optical fiber detecting probe head for portable raman spectrometer Download PDFInfo
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- CN102589700A CN102589700A CN2012100469477A CN201210046947A CN102589700A CN 102589700 A CN102589700 A CN 102589700A CN 2012100469477 A CN2012100469477 A CN 2012100469477A CN 201210046947 A CN201210046947 A CN 201210046947A CN 102589700 A CN102589700 A CN 102589700A
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- optical fiber
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- detection probe
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Abstract
The invention relates to an optical fiber detecting probe head, in particular to an optical fiber detecting probe head for a portable raman spectrometer. The optical fiber detecting probe head for the portable raman spectrometer is characterized by comprising a probe head component and a plurality of collecting optical fibers (9), wherein one ends of the collecting optical fibers (9) are simultaneously connected with the probe head component, and another ends of the collecting optical fibers (9) are simultaneously connected with an FC (fiber channel) probe head; and the optical fiber detecting probe head for the portable raman spectrometer further comprises an exciting optical fiber (10), wherein one end of the exciting optical fiber (10) is connected with the probe head component, and another end of the exciting optical fiber (10) is connected with an SMA905 interface. Therefore, the optical fiber detecting probe head has the advantages that the optical fiber detecting probe head is mini, efficient, and suitable for the clinic detection of the early digestive tract cancer, and the raman light collecting efficiency at the side wall of the upper digestive tract can be improved.
Description
Technical field
The present invention relates to a kind of optical fiber detection probe, especially relate to the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance uses.
Background technology
Raman spectrum as a kind of harmless, fast analytical technology be widely used in that medical science detects and clinical diagnosis in, yet detect the conceptual phase that also rests on the early diagnosis of exsomatizing at present for the higher UGI cancer of the incidence of disease.Raman spectrum depends on efficiently, collects easily the Raman light system in the application of clinical diagnose, the Raman fiber detection probe then is the important component part of this system.Present commercial Raman fiber probe all is to be applied to industrial circle, and volume is greatly that it can not be applied to the disadvantage that internal in-situ detects.External also have the small size Raman fiber detection probe report of in-situ Raman detection in vivo, but its efficient of collecting Raman light is extremely low.In addition as far as our knowledge goes; All Raman fiber detection probe all are to collect Raman light on the top at present; Very unfavorable for the Raman light signal of collecting the UGI sidewall like this, therefore designing a kind of Raman probe that can collect sidewall Raman light signal efficiently becomes necessary.
Summary of the invention
The present invention solves the technical matters that the existing commercialization Raman fiber probe of existing in prior technology can not the internal in-situ detection etc.; Provide a kind of miniature, be applicable to the early stage Clinical detection of UGI cancer efficiently, and can improve the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance in the Raman light collection efficiency of UGI sidewall uses.
Above-mentioned technical matters of the present invention mainly is able to solve through following technical proposals:
The optical fiber detection probe that a kind of Portable Raman optical spectrum appearance uses is characterized in that, comprises that a probe assembly and some ends are connected with probe assembly simultaneously, the collection optical fiber that the other end is connected with the FC probe simultaneously; The optical fiber detection probe that this Portable Raman optical spectrum appearance uses comprises that also one one end is connected with probe assembly, and the other end is connected with the excitation fiber of a SMA905 interface.
In the optical fiber detection probe that above-mentioned a kind of Portable Raman optical spectrum appearance uses, described probe assembly comprises a metal sleeve and is arranged on filtering apparatus in the metal sleeve and the reflection unit that is arranged on filtering apparatus one side; The end that above-mentioned collection optical fiber is connected with probe assembly inserts metal sleeve to filtering apparatus opposite side; The end that above-mentioned excitation fiber is connected with probe assembly inserts metal sleeve to filtering apparatus opposite side.
Optical fiber detection probe in above-mentioned a kind of Portable Raman optical spectrum appearance use; Said filtering apparatus comprises a long pass filter of annular and is arranged on long pass filter circular hole place, middle part and contacts good bandpass filter with circular-hole internal-wall that the end that above-mentioned collection optical fiber inserts metal sleeve contacts with long pass filter; The end that above-mentioned excitation fiber is inserted metal sleeve contacts with bandpass filter.
In the optical fiber detection probe that above-mentioned a kind of Portable Raman optical spectrum appearance uses, said collection optical fiber is 6, is that the center centers on the rounded arrangement of excitation fiber with the excitation fiber.
Optical fiber detection probe in above-mentioned a kind of Portable Raman optical spectrum appearance use; Said metal sleeve inwall is provided with a placement hole; Said reflection unit comprises the plated film globe lens that is arranged on the gold-plated catoptron that is positioned at filtering apparatus one side in the metal sleeve and is arranged on the placement hole of gold-plated catoptron below metal sleeve inwall, and said gold-plated catoptron and metal sleeve inwall are 45 ° and are obliquely installed.
Optical fiber detection probe in above-mentioned a kind of Portable Raman optical spectrum appearance use; Also be provided with a loose sleeve pipe in the said metal sleeve; The end that above-mentioned collection optical fiber and excitation fiber are inserted in the metal sleeve all is arranged in the loose sleeve pipe, is provided with machine potting resin layer between said loose sleeve outer wall and the metal sleeve inwall.
In the optical fiber detection probe that above-mentioned a kind of Portable Raman optical spectrum appearance uses, said plated film globe lens diameter is 1.5 mm, and said placement hole diameter is less than plated film globe lens diameter.
In the optical fiber detection probe that above-mentioned a kind of Portable Raman optical spectrum appearance uses, said collection fibre diameter is 400 μ m, and said excitation fiber diameter is 150 μ m.
Therefore, the present invention has following advantage: miniature, be applicable to the early stage Clinical detection of UGI cancer efficiently, and can improve Raman light collection efficiency at the UGI sidewall.
Description of drawings
Fig. 1 is a kind of main TV structure diagrammatic cross-section of the present invention.
Fig. 2 is the sectional structure synoptic diagram at A place among Fig. 1.
Embodiment
Pass through embodiment below, and combine accompanying drawing, do further bright specifically technical scheme of the present invention.Among the figure, bandpass filter 1, gold-plated catoptron 2, metal sleeve 3, plated film globe lens 4, testing sample 5, long pass filter 6, loose sleeve pipe 7, organic potting resin layer 8, collection optical fiber 9, excitation fiber 10.
Embodiment:
The present invention includes a probe assembly and 6 one ends and is connected with probe assembly simultaneously, the collection optical fiber 10 that the other end is popped one's head in and is connected with FC simultaneously; The optical fiber detection probe that this Portable Raman optical spectrum appearance uses comprises that also one one end is connected with probe assembly, and the other end is connected with the excitation fiber 11 of a SMA905 interface, and collecting optical fiber is that the center is around excitation fiber 11 rounded arrangements with excitation fiber 11.
Probe assembly comprises that an inwall is provided with the metal sleeve 3 of organic potting resin layer 8 and is arranged on filtering apparatus in the metal sleeve 3 and the reflection unit that is arranged on filtering apparatus one side; Collect end insertion metal sleeve 3 to the filtering apparatus opposite side that optical fiber 9 is connected with probe assembly; The end that excitation fiber 10 is connected with probe assembly inserts metal sleeve 3 to filtering apparatus opposite side; Also be provided with a loose sleeve pipe 7 in the metal sleeve 3; Above-mentioned collection optical fiber 9 all is arranged in the loose sleeve pipe 7 with the end that excitation fiber 10 is inserted in the metal sleeve 3, is provided with machine potting resin layer 8 between said loose sleeve pipe 7 outer walls and metal sleeve 3 inwalls
Filtering apparatus comprises a long pass filter 6 of annular and is arranged on long pass filter circular hole place, 6 middle part and contacts good bandpass filter 1 with circular-hole internal-wall that an end of collecting optical fiber 9 insertion metal sleeves 3 contacts with long pass filter 6; The end that excitation fiber 10 is inserted metal sleeve 3 contacts with bandpass filter 1; Metal sleeve 3 inwalls are provided with a placement hole; Said reflection unit comprises the plated film globe lens 4 that is arranged on the gold-plated catoptron 2 that is positioned at filtering apparatus one side in the metal sleeve 3 and is arranged on the placement hole of gold-plated catoptron 2 below metal sleeves 3 inwalls, and said gold-plated catoptron 2 is 45 ° with metal sleeve 3 inwalls and is obliquely installed.
In the present embodiment, plated film globe lens 4 diameters are 1.5 mm, and said placement hole diameter is less than plated film globe lens 4 diameters, and collecting fibre diameter is 400 μ m, and said excitation fiber diameter is 150 μ m.The length of metal tube is 3 cm, and outer wrap the medical teleflex of one deck, and overall diameter is 2.6 mm.The outer optical fiber that connects of probe is by soft metal sleeve pipe and medical teleflex parcel.
During assembling; At first the FC interface is connected on the fiber laser through optical fiber; SMA 905 interfaces are connected on the Raman spectrometer; In the present embodiment, fiber laser emission gloss uses the laser beam of wavelength as 785nm, long pass filter 6 employings can wavelength-filtered less than the optical filter of 785nm light beam.
The concrete path of light is in the present embodiment: 785nm laser passes bandpass filter 1 level via excitation fiber 10 and penetrates on gold-plated catoptron 2; Plated film globe lens 4 is passed in reflection through gold-plated catoptron 2, and plated film globe lens 4 converges parallel exciting light and gets on the testing sample 5.The Raman light signal that reflects from testing sample 5 is gathered into directional light by plated film globe lens 4 again and is incident on the gold-plated catoptron 2, incides on the long pass filter 6 via the reflection levels of gold-plated catoptron 2, collects in the spectrometer via collecting optical fiber 9 again.
Specific embodiment described herein only is that the present invention's spirit is illustrated.Person of ordinary skill in the field of the present invention can make various modifications or replenishes or adopt similar mode to substitute described specific embodiment, but can't depart from spirit of the present invention or surmount the defined scope of appended claims.
Although this paper has used bandpass filter 1, gold-plated catoptron 2, metal sleeve 3, plated film globe lens 4, testing sample 5, long pass filter 6, loose sleeve pipe 7, organic potting resin layer 8, collected terms such as optical fiber 9, excitation fiber 10 morely, do not get rid of the possibility of using other term.Using these terms only is in order to describe and explain essence of the present invention more easily; It all is contrary with spirit of the present invention being construed to any additional restriction to them.
Claims (8)
1. the optical fiber detection probe that the Portable Raman optical spectrum appearance uses is characterized in that, comprises that a probe assembly and some ends are connected with probe assembly simultaneously, the collection optical fiber (9) that the other end is connected with the FC probe simultaneously; The optical fiber detection probe that this Portable Raman optical spectrum appearance uses comprises that also one one end is connected with probe assembly, and the other end is connected with the excitation fiber (10) of a SMA905 interface.
2. the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance according to claim 1 uses; It is characterized in that described probe assembly comprises a metal sleeve (3) and is arranged on filtering apparatus in the metal sleeve (3) and the reflection unit that is arranged on filtering apparatus one side; The end that above-mentioned collection optical fiber (9) is connected with probe assembly inserts metal sleeve (3) to the filtering apparatus opposite side; The end that above-mentioned excitation fiber (10) is connected with probe assembly inserts metal sleeve (3) to the filtering apparatus opposite side.
3. the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance according to claim 2 uses; It is characterized in that; Said filtering apparatus comprises an annular long pass filter (6) and is arranged on long pass filter (6) circular hole place, middle part and contacts good bandpass filter (1) with circular-hole internal-wall that the end that above-mentioned collection optical fiber (9) inserts metal sleeve (3) contacts with long pass filter (6); The end that above-mentioned excitation fiber (10) is inserted metal sleeve (3) contacts with bandpass filter (1).
4. the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance according to claim 3 uses is characterized in that said collection optical fiber (9) is 6, is that the center is around the rounded arrangement of excitation fiber (10) with excitation fiber (10).
5. the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance according to claim 2 uses; It is characterized in that; Said metal sleeve (3) inwall is provided with a placement hole; Said reflection unit comprises the plated film globe lens (4) that is arranged on the gold-plated catoptron (2) that is positioned at filtering apparatus one side in the metal sleeve (3) and is arranged on the placement hole of gold-plated catoptron (2) below metal sleeve (3) inwall, and said gold-plated catoptron (2) and metal sleeve (3) inwall are 45 ° and are obliquely installed.
6. the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance according to claim 2 uses; It is characterized in that; Also be provided with a loose sleeve pipe (7) in the said metal sleeve (3); The end that above-mentioned collection optical fiber (9) and excitation fiber (10) are inserted in the metal sleeve (3) all is arranged in the loose sleeve pipe (7), is provided with machine potting resin layer (8) between said loose sleeve pipe (7) outer wall and metal sleeve (3) inwall.
7. the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance according to claim 5 uses is characterized in that said plated film globe lens (4) diameter is 1.5 mm, and said placement hole diameter is less than plated film globe lens (4) diameter.
8. the optical fiber detection probe that a kind of Portable Raman optical spectrum appearance according to claim 1 uses is characterized in that said collection fibre diameter is 400 μ m, and said excitation fiber diameter is 150 μ m.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100469477A CN102589700A (en) | 2012-02-28 | 2012-02-28 | Optical fiber detecting probe head for portable raman spectrometer |
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| CN2012100469477A CN102589700A (en) | 2012-02-28 | 2012-02-28 | Optical fiber detecting probe head for portable raman spectrometer |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102928395A (en) * | 2012-10-18 | 2013-02-13 | 武汉大学 | Laser Raman spectrometer system for in-situ early diagnosis of upper gastrointestinal cancer |
| CN103776815A (en) * | 2014-02-24 | 2014-05-07 | 南京派光信息技术有限公司 | Portable adjustable Raman probe |
| CN103822910A (en) * | 2012-11-16 | 2014-05-28 | 福州高意通讯有限公司 | Raman probes for miniature Raman spectrometer |
| CN104458697A (en) * | 2014-12-08 | 2015-03-25 | 成都鼎智汇科技有限公司 | Portable raman spectrum explosive identifier |
| CN104603601A (en) * | 2012-08-16 | 2015-05-06 | 新加坡国立大学 | Diagnostic instrument and methods relating to raman spectroscopy |
| CN104932087A (en) * | 2015-05-15 | 2015-09-23 | 奥普多威（开曼）控股有限公司 | Integrated optical coherent detection probe |
| CN105044075A (en) * | 2015-06-24 | 2015-11-11 | 中国电子科技集团公司第三十八研究所 | Mini-type optical fiber detection probe for raman spectrometer |
| CN105190262A (en) * | 2013-02-19 | 2015-12-23 | 新加坡国立大学 | Diagnostic instrument and method |
| CN105358947A (en) * | 2013-02-14 | 2016-02-24 | 曾海山 | Integrated spectral probe for raman, reflectance and fluorescence spectral measurements |
| WO2018015951A1 (en) * | 2016-07-20 | 2018-01-25 | Verifood, Ltd. | Accessories for handheld spectrometer |
| CN109557077A (en) * | 2019-01-23 | 2019-04-02 | 江西农业大学 | Portable multifunctional Raman spectrum for Detecting Pesticide in fruit and fruit juice acquires attachment |
| CN109557076A (en) * | 2019-01-23 | 2019-04-02 | 江西农业大学 | Portable Raman optical spectrum for fruit quality detection acquires attachment |
| CN109730694A (en) * | 2019-01-08 | 2019-05-10 | 北京信息科技大学 | The raman spectroscopy measurement probe of plaque type in a kind of diagnosis human vas |
| US11333552B2 (en) | 2014-10-23 | 2022-05-17 | Verifood, Ltd. | Accessories for handheld spectrometer |
| CN115420382A (en) * | 2022-08-16 | 2022-12-02 | 元珵科技(北京)有限公司 | Raman probe and working system and working method thereof |
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Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104603601A (en) * | 2012-08-16 | 2015-05-06 | 新加坡国立大学 | Diagnostic instrument and methods relating to raman spectroscopy |
| CN104603601B (en) * | 2012-08-16 | 2017-08-22 | 新加坡国立大学 | The diagnostic instrments relevant with Raman spectroscopy and method |
| CN102928395A (en) * | 2012-10-18 | 2013-02-13 | 武汉大学 | Laser Raman spectrometer system for in-situ early diagnosis of upper gastrointestinal cancer |
| CN103822910A (en) * | 2012-11-16 | 2014-05-28 | 福州高意通讯有限公司 | Raman probes for miniature Raman spectrometer |
| CN105358947B (en) * | 2013-02-14 | 2018-03-16 | 曾海山 | Integration spectrum for Raman, reflection and fluorescence spectral measuring is popped one's head in |
| CN105358947A (en) * | 2013-02-14 | 2016-02-24 | 曾海山 | Integrated spectral probe for raman, reflectance and fluorescence spectral measurements |
| CN105190262A (en) * | 2013-02-19 | 2015-12-23 | 新加坡国立大学 | Diagnostic instrument and method |
| CN103776815A (en) * | 2014-02-24 | 2014-05-07 | 南京派光信息技术有限公司 | Portable adjustable Raman probe |
| CN103776815B (en) * | 2014-02-24 | 2016-05-04 | 南京派光信息技术有限公司 | A kind of portable adjustable Raman probe |
| US11333552B2 (en) | 2014-10-23 | 2022-05-17 | Verifood, Ltd. | Accessories for handheld spectrometer |
| CN104458697A (en) * | 2014-12-08 | 2015-03-25 | 成都鼎智汇科技有限公司 | Portable raman spectrum explosive identifier |
| CN104932087A (en) * | 2015-05-15 | 2015-09-23 | 奥普多威（开曼）控股有限公司 | Integrated optical coherent detection probe |
| CN105044075B (en) * | 2015-06-24 | 2017-12-05 | 中国电子科技集团公司第三十八研究所 | A kind of Raman spectrometer mini optical fibre detection probe |
| CN105044075A (en) * | 2015-06-24 | 2015-11-11 | 中国电子科技集团公司第三十八研究所 | Mini-type optical fiber detection probe for raman spectrometer |
| WO2018015951A1 (en) * | 2016-07-20 | 2018-01-25 | Verifood, Ltd. | Accessories for handheld spectrometer |
| US11378449B2 (en) | 2016-07-20 | 2022-07-05 | Verifood, Ltd. | Accessories for handheld spectrometer |
| CN109730694A (en) * | 2019-01-08 | 2019-05-10 | 北京信息科技大学 | The raman spectroscopy measurement probe of plaque type in a kind of diagnosis human vas |
| CN109557077A (en) * | 2019-01-23 | 2019-04-02 | 江西农业大学 | Portable multifunctional Raman spectrum for Detecting Pesticide in fruit and fruit juice acquires attachment |
| CN109557076A (en) * | 2019-01-23 | 2019-04-02 | 江西农业大学 | Portable Raman optical spectrum for fruit quality detection acquires attachment |
| CN115420382A (en) * | 2022-08-16 | 2022-12-02 | 元珵科技(北京)有限公司 | Raman probe and working system and working method thereof |
| CN115420382B (en) * | 2022-08-16 | 2024-03-12 | 元珵科技(北京)有限公司 | Raman probe, working system and working method thereof |
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Application publication date: 20120718 |