CN102709705A - MRI (magnetic resonance imaging) magnetic signal enhancement device - Google Patents
MRI (magnetic resonance imaging) magnetic signal enhancement device Download PDFInfo
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- CN102709705A CN102709705A CN2012101282222A CN201210128222A CN102709705A CN 102709705 A CN102709705 A CN 102709705A CN 2012101282222 A CN2012101282222 A CN 2012101282222A CN 201210128222 A CN201210128222 A CN 201210128222A CN 102709705 A CN102709705 A CN 102709705A
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Abstract
The invention provides an MRI (magnetic resonance imaging) magnetic signal enhancement device arranged between a portion to be detected and a magnetic signal receiving coil of an MRI device. The MRI magnetic signal enhancement device comprises a housing and at least one tier of negative permeability metamaterial arranged in the housing. The negative permeability metamaterial is specially designed low-frequency negative permeability metamaterial. When permeability of the negative permeability metamaterial in the MRI magnetic signal enhancement device is negative and resonance frequency and MRI working frequency are consistent, the negative permeability metamaterial responds to the receiving coil of the MRI device, magnetic signals of the receiving coil are enhanced, and imaging quality of an MRI system is further improved. In addition, the imaging quality of the MRI system is improved, and accordingly the receiving coil of the MRI device need not cling to the portion to be detected, and comfort in using the MRI device is increased.
Description
Technical field
The present invention relates to the MRI field, relate to a kind of MRI magnetic signal enhance device particularly.
Background technology
The principle of nulcear magnetic resonance (NMR) (MRI) imaging system is to utilize coil to remove to detect the radio wave pulses energy that nuclear spin absorbs and launches, and this coil is being gone back simultaneously as transmitting coil as receiving coil sometimes.Under the help of radio wave pulses energy, the Magnetic resonance imaging scanner can the position patient body in a very little point, confirm that then this is the tissue of which kind of type.The magnetic resonance imaging machine device adopts the radio frequency pulse specific to hydrogen atom.The system pilot pulse is aimed at the body region that institute will check, and causes this regional proton to absorb they are rotated or the required energy of precession with different directions.This is NMR imaging device " resonance " part.Radio frequency pulse forces their (referring to a pair of or two pairs of unmatched protons unnecessary in each 1,000,000 proton) under CF, to be rotated according to specific direction.The CF that causes resonance is called as Rameau that frequency, and this value is to calculate according to the magnetic field intensity of the particular organization that will form images and main field to draw.Radio frequency pulse utilizes a coil to provide usually, and this coil is called transmitting coil.The necessary quite near-earth of the receiving coil of existing Magnetic resonance imaging equipment is near detected part, to obtain the magnetic signal that is discharged by detected part.The definition and the main field strength of MRI imaging device are proportionate, and the main magnetic field magnet system is the major part of MRI imaging device, in order to promote the image quality of MRI imaging system, generally need to change whole MRI imaging device, and cost is very high.
Ultra material is meant artificial composite structure or the composite material that some have the not available extraordinary physical property of natural material.Structurally ordered design through on the key physical yardstick of material can break through the restriction of some apparent natural law, thereby obtains to exceed the meta-materials function of the intrinsic common character of nature.The character of ultra material and function mainly come from its inner structure but not constitute their material.At present; The geometry of the artificial micro-structural of existing metal is the perhaps open annular of similar " recessed " font as shown in Figure 1 of " worker " font; But this structure all can not realize magnetic permeability μ and be significantly less than 0 or ultra material resonances frequency is reduced, and can not realize isotropism, has only the artificial micro-structural of metal that has the special geometric figure through design; Could make this artificial electromagnetic material in special frequency, reach magnetic permeability μ value, and have lower resonance frequency less than 0.
At present, international community is to the existing a large amount of research in magnetic permeability aspect, and wherein the research for positive magnetic permeability has been tending towards ripe; Research for the ultra material of negative magnetoconductivity is the focus of studying both at home and abroad now, and negative magnetoconductivity has the quantum polarization, can produce polarization to incident wave; Therefore sphere of action is very big, and like the mr imaging technique in the medical imaging field, negative magnetic-inductive capacity material can be strengthened electromagnetic imaging effect; Negative magnetic-inductive capacity material is also playing an important role aspect the lens research in addition; In the engineering field, magnetic permeability all is meant relative permeability usually, is the absolute permeability μ and the magnetic constant μ of material
0The ratio of (claiming permeability of vacuum again), μ
r=μ/μ
0, dimensionless number.Usually " relatively " two words and symbol subscript r are removed.Magnetic permeability is to represent that material receives magnetizing field H and does the time spent, and inner true magnetic field is with respect to the degree of increase (μ＞1) or the minimizing (μ＜1) of H.So far in the already present material of finding of nature, μ is generally greater than 0.
Summary of the invention
Technical problem to be solved by this invention is: a kind of MRI magnetic signal enhance device is provided; This MRI magnetic signal enhance device is the ultra material of negative magnetoconductivity; The image quality of Contrast-enhanced MRI imaging device, simultaneously, the image quality of MRI imaging device strengthens; Can make the receiving coil of MRI imaging device increase the comfortableness that the MRI imaging device uses near detected part.
The present invention for realizing the technical scheme that goal of the invention adopts is: a kind of MRI magnetic signal enhance device is provided; MRI magnetic signal enhance device is arranged between the magnetic signal receiving coil of detected part and MRI imaging device; MRI magnetic signal enhance device comprises shell and the ultra material of the negative magnetoconductivity of one deck at least in the enclosure is set; The ultra material of negative magnetoconductivity comprises substrate and is fixed on the artificial microstructured layers on the substrate; The periodic a plurality of artificial micro-structurals of array arrangement on the artificial microstructured layers; Artificial micro-structural is made up of four identical artificial microstructure units, and arbitrary artificial microstructure unit overlaps with other three artificial microstructure units respectively behind same rotating shaft half-twist, 180 °, 270 °, and artificial microstructure unit is formed the spill split ring resonator of multinest through the mode of multiple coiling by a wires.
Preferably, ultra material is by two-layer substrate and three layers of alternate cascading of artificial microstructured layers.
Preferably, the position of artificial microstructure unit is one to one, and artificial microstructure unit opening direction does, the opening direction of two outer artificial microstructure units is identical, and the opening direction of artificial microstructure unit in intermediate layer and outer artificial microstructure unit is opposite.
Preferably, substrate is FR-4 organic polymer substrate or ceramic substrate.
Preferably, the thickness of substrate is 0.10-0.30mm.
Preferably, metal wire live width 0.05-0.15mm.
Preferably, metal wire distance between centers of tracks 0.05-0.15mm.
Preferably, metal wire line thickness 0.015-0.020mm.
Preferably, artificial micro-structural is of a size of 30mm * 30mm.
Preferably, the metal wire winding turns is greater than 2.
The invention has the beneficial effects as follows: a kind of MRI magnetic signal enhance device is provided; MRI magnetic signal enhance device utilizes the magnetic permeability of the ultra material of negative magnetoconductivity for negative this characteristic, reaches the effect that signal strengthens, and makes MRI imaging device imaging effect better; Simultaneously; MRI equipment image quality strengthens, and can make the receiving coil of MRI equipment increase the comfortableness that MRI equipment uses near detected part.
Description of drawings
Fig. 1, the artificial micro-structural sketch map of the ultra material of prior art negative magnetoconductivity;
Fig. 2, MRI magnetic signal enhance device sketch map;
Fig. 3, the artificial microstructure unit sketch map of the ultra material of negative magnetoconductivity of the present invention;
Fig. 4, the artificial microstructure unit opening direction of Fig. 3 sketch map;
Fig. 5, negative magnetoconductivity metamaterial structure sketch map of the present invention;
Fig. 6, the right view of Fig. 5;
Fig. 7, the artificial micro-structural sketch map of the ultra material of negative magnetoconductivity of the present invention;
Fig. 8, artificial microstructure unit polar coordinates sketch map;
Fig. 9, the ultra material simulated effect of prior art negative magnetoconductivity sketch map;
Figure 10, the ultra material simulated effect of negative magnetoconductivity of the present invention sketch map;
Figure 11, the MRI animal coronal-plane effect contrast figure that exsomatizes;
Among the figure, the ultra material of 10 negative magnetoconductivities, 12 shells, 1 artificial microstructure unit opening part, a, b, the artificial microstructured layers of c, d, e substrate.
Embodiment
Below in conjunction with accompanying drawing and embodiment the present invention is elaborated.
Shown in Figure 1 is the artificial micro-structural of open annular of similar " recessed " of the prior art font; The artificial micro-structural of this shape can make ultra material magnetic permeability for negative; But the resonance frequency that reaches negative magnetoconductivity is higher; Shown in the existing ultra material technology simulated effect of the negative magnetoconductivity sketch map of Fig. 9, above-mentioned artificial micro-structural shape reaches magnetic permeability and surpasses 350MHz for negative resonance frequency.
Fig. 2 is a MRI magnetic signal enhance device sketch map, and MRI magnetic signal enhance device of the present invention comprises shell 12 and is arranged on the ultra material 10 of the negative magnetoconductivity of one deck at least in the shell 12.Should be appreciated that shell 12 of the present invention plays the effect of support, the ultra material 10 of protection internal layer negative magnetoconductivity,, during like shank, neck, can carry out conformal design, be convenient to the user and use according to concrete needs to shell 12 measuring some privileged sites.If there is the ultra material 10 of two-layer above negative magnetoconductivity shell 12 inside, can be with its coaxial secured in parallel.
Fig. 3 shows the artificial microstructure unit sketch map of the present invention, and the artificial microstructure unit of the present invention is for being formed the spill split ring resonator of multinest through the mode of multiple coiling by a wires.1 is the opening part of artificial microstructure unit, and hence one can see that, and its opening direction upwards; Referring to Fig. 4, equidistantly array arrangement is on substrate d, e surface ringwise for four artificial microstructure units, and the position of artificial microstructure unit is one to one; Artificial microstructure unit opening direction does, the opening direction of two outer artificial microstructure units is identical, and the opening direction of artificial microstructure unit in intermediate layer and outer artificial microstructure unit is opposite; Form artificial micro-structural; Referring to Fig. 7, a plurality of artificial micro-structural cyclic arrays are arranged in substrate d, e surface, form artificial microstructured layers a, b, c; Substrate d, e and artificial microstructured layers a, b, the ultra material 10 of the alternate range upon range of composition negative magnetoconductivity of c are referring to Fig. 5.
Should be appreciated that a plurality of artificial micro-structurals are periodicity and arrange on the surface of substrate d, e, as shown in Figure 6; Rectangular array is arranged; Promptly be row, serve as that row ground is arranged, and each line space, each column pitch equate respectively, even line space equals column pitch and all can with y direction perpendicular to the x direction with an x direction.Preferred line space, column pitch be not more than the incident electromagnetic wave that will respond wavelength 1/4th; Promptly for example operational environment is that wavelength is the electromagnetic wave of λ; Needing ultra material is to present negative magnetoconductivity to this electromagnetic electromagnetic property; When then designing artificial micro-structural above-mentioned line space, column pitch are selected to be not more than quarter-wave, be preferably 1/10th wavelength.
The metal wire material that should be appreciated that the artificial micro-structural of the present invention is copper cash, silver-colored line, or even gold thread.Metal wire live width 0.05-0.15mm, metal wire distance between centers of tracks 0.05-0.15mm, metal wire line thickness 0.015-0.020mm, the metal wire winding turns is greater than 2, and artificial micro-structural is of a size of 30mm * 30mm.
Should be appreciated that the circle of this paper, be meant as shown in Figure 8ly, a bit be polar limit O with ring-shaped inner part that split ring resonator was surrounded
e, leave limit O in split ring resonator two distal points
eNear distal point line to the extreme is this polar pole axis, and getting is positive direction counterclockwise, then uses polar coordinates (ρ successively along the every bit on the split ring resonator
e, represent that θ) every one 360 degree is a circle, up to reach split ring resonator from limit another distal point far away.
Should be appreciated that substrate d, e are FR-4 organic polymer substrate or ceramic substrate, the thickness of substrate d, e is 0.10-0.30mm.
Figure 10 is the ultra material simulated effect of negative magnetoconductivity of the present invention sketch map, and the simulation software that simulation software and Fig. 9 use is CST MICROWAVE STUDIO 2010, and simulation parameter is: metal wire is selected copper cash; Copper cash live width 0.1mm, copper cash distance between centers of tracks 0.1mm, copper cash line thickness 0.018mm; Substrate is the FR-4 epoxy resin base plate, thickness 0.018mm, artificial microstructure size 30mm * 30mm; Can know by simulation result; The ultra material of negative magnetoconductivity of the present invention realize magnetic permeability be-1 resonance frequency below 10MHz, compared with prior art, greatly reduce the resonance frequency of the ultra material of negative magnetoconductivity.
Based on the ultra material of above-mentioned low resonant frequency negative magnetoconductivity; Process MRI magnetic signal enhance device as shown in Figure 2, this magnetic signal enhance device places between the receiving coil and user of MRI equipment, when the ultra material of negative magnetoconductivity in the MRI magnetic signal enhance device at magnetic permeability when negative; And under the resonance frequency situation identical with the MRI operating frequency; The receiving coil of ultra material of negative magnetoconductivity and MRI equipment produces response, strengthens the magnetic signal of receiving coil, and then the image quality of Contrast-enhanced MRI system.
Shown in figure 11, left side figure is the stripped coronal-plane effect contrast figure of animal who does not add MRI magnetic signal enhance device, and animal is exsomatized and is the fresh in vitro leg of pork among the figure; Right figure is the same leg of pork uses identical MRI equipment after adding a MRI magnetic signal enhance device of the present invention image, can know through contrast, after the adding MRI magnetic signal enhance device; It is more clear that the muscle that animal is exsomatized, bone texture show; Image is brighter, and the MRI imaging effect obviously improves, and is convenient to the doctor and diagnoses.Simultaneously, the image quality of Contrast-enhanced MRI system can make the receiving coil of MRI equipment increase the comfortableness that MRI equipment uses near detected part.
The foregoing description among the present invention has only been done exemplary description, and those skilled in the art can carry out various modifications to the present invention under the situation that does not break away from the spirit and scope of the present invention after reading present patent application.
Claims (10)
1. MRI magnetic signal enhance device; It is characterized in that; Said MRI magnetic signal enhance device is arranged between the magnetic signal receiving coil of detected part and MRI imaging device; Said MRI magnetic signal enhance device comprises shell and the ultra material of the negative magnetoconductivity of one deck at least in the enclosure is set; The ultra material of said negative magnetoconductivity comprises substrate and is fixed on the artificial microstructured layers on the substrate, the periodic a plurality of artificial micro-structurals of array arrangement on the said artificial microstructured layers, and said artificial micro-structural is made up of four identical artificial microstructure units; Said arbitrary artificial microstructure unit overlaps with other three artificial microstructure units respectively behind same rotating shaft half-twist, 180 °, 270 °, and said artificial microstructure unit is formed the spill split ring resonator of multinest through the mode of multiple coiling by a wires.
2. MRI magnetic signal enhance device according to claim 1 is characterized in that, said ultra material is by two-layer said substrate and three layers of alternate cascading of said artificial microstructured layers.
3. MRI magnetic signal enhance device according to claim 1; It is characterized in that; The position of said artificial microstructure unit is one to one; Said artificial microstructure unit opening direction does, the opening direction of two outer artificial microstructure units is identical, and the opening direction of artificial microstructure unit in intermediate layer and outer artificial microstructure unit is opposite.
4. MRI magnetic signal enhance device according to claim 1 is characterized in that said substrate is FR-4 organic polymer substrate or ceramic substrate.
5. MRI magnetic signal enhance device according to claim 1 is characterized in that the thickness of said substrate is 0.10-0.30mm.
6. the ultra material of negative magnetoconductivity according to claim 1 is characterized in that, said metal wire live width 0.05-0.15mm.
7. the ultra material of negative magnetoconductivity according to claim 1 is characterized in that, said metal wire distance between centers of tracks 0.05-0.15mm.
8. the ultra material of negative magnetoconductivity according to claim 1 is characterized in that, said metal wire line thickness 0.015-0.020mm.
9. MRI magnetic signal enhance device according to claim 1 is characterized in that said artificial micro-structural is of a size of 30mm * 30mm.
10. MRI magnetic signal enhance device according to claim 1 is characterized in that said metal wire winding turns is greater than 2.
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| CN104409863A (en) * | 2014-11-27 | 2015-03-11 | 骆柳春 | MRI magnetic signal enhancing device |
| CN104409866A (en) * | 2014-11-27 | 2015-03-11 | 骆柳春 | Magnetic signal enhancement device |
| CN104409865A (en) * | 2014-11-27 | 2015-03-11 | 骆柳春 | MRI magnetic signal enhancing component |
| CN104459585A (en) * | 2014-11-27 | 2015-03-25 | 骆柳春 | Magnetic signal enhancement device used for magnetic resonance imaging |
| RU2601373C1 (en) * | 2015-07-03 | 2016-11-10 | федеральное государственное автономное образовательное учреждение высшего образования "Санкт-Петербургский национальный исследовательский университет информационных технологий, механики и оптики" (Университет ИТМО) | Magnetic resonance tomographic scanner |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104409863A (en) * | 2014-11-27 | 2015-03-11 | 骆柳春 | MRI magnetic signal enhancing device |
| CN104409866A (en) * | 2014-11-27 | 2015-03-11 | 骆柳春 | Magnetic signal enhancement device |
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| CN107835658A (en) * | 2015-07-03 | 2018-03-23 | 圣彼得堡国立信息技术机械与光学大学 | Magnetic resonance imaging machine |
| KR20180040572A (en) * | 2015-07-03 | 2018-04-20 | 세인트 피터스버그 내셔널 리서치 유니버시티 오브 인포메이션 테크놀로지스, 메카닉스 앤드 옵틱스 (아이티엠오 유니버시티) | Magnetic resonance imaging device |
| EA033641B1 (en) * | 2015-07-03 | 2019-11-12 | Federal State Autonomous Educational Institution Of Higher Education Saint Petersburg National Resea | Magnetic resonance imaging machine |
| US10732237B2 (en) | 2015-07-03 | 2020-08-04 | Saint Petersburg National Research University Of Information Technologies, Mechanics And Optics (Itmo University) | Magnetic resonance imaging machine |
| CN107835658B (en) * | 2015-07-03 | 2022-03-15 | 圣彼得堡国立信息技术机械与光学大学 | Magnetic resonance imaging machine |
| KR102495322B1 (en) * | 2015-07-03 | 2023-02-01 | 세인트 피터스버그 내셔널 리서치 유니버시티 오브 인포메이션 테크놀로지스, 메카닉스 앤드 옵틱스 (아이티엠오 유니버시티) | magnetic resonance imaging device |
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