CN102908188A

CN102908188A - Radio frequency ablation (RFA) catheter system for denervation of renal sympathetic nerves

Info

Publication number: CN102908188A
Application number: CN2012103130879A
Authority: CN
Inventors: 宋治远; 杨攀; 钟理; 王子洪; 廖新华; 仝识非; 舒茂琴
Original assignee: First Affiliated Hospital of TMMU
Current assignee: Third Military Medical University TMMU; First Affiliated Hospital of TMMU
Priority date: 2012-08-29
Filing date: 2012-08-29
Publication date: 2013-02-06
Anticipated expiration: 2032-08-29
Also published as: CN102908188B

Abstract

The invention provides a radio frequency ablation (RFA) catheter system for denervation of sympathetic nerves in renal arteries. The system comprises an ablation catheter, a control handle, a guiding catheter and an ablation generating device and can be provided or not provided with an independent guiding catheter control handle, wherein the ablation catheter is formed by a catheter body section and an ablation section from near end to far end in sequence. The system is characterized in that the front end of the catheter body section also comprises a controllable bending section; the controllable bending section is connected with the control handle by the catheter body section; at least two independent structures are installed on the ablation section; and an ablation head is installed on at least one independent structure. The system can carry out multipoint ablation simultaneously, monitors the ablation effect during operation in real time, and has better mechanical stability.

Description

Kidney goes to sympathetic nerve radio frequency ablation catheter system

Technical field

The present invention relates to a kind of medical apparatus and instruments, specifically a kind of be used for Hypertension, enter the orthosympathetic radio frequency ablation catheter of blocking-up kidney system in the renal artery by the mode that gets involved.

Background technology

Hypertension is common clinical, frequently-occurring disease, calculates according to up-to-date data, and Chinese hyperpietic group surpasses 200,000,000, and is number of the infected and increases year by year, and age of onset is trend in advance gradually.The important organ complication such as the heart that hypertension causes, brain, kidney have very high fatality rate and disability rate, and human health in serious harm.China has 3000～4,000 ten thousand obstinate hypertension approximately, and the following increase that is accompanied by aged tendency of population and obesity, diabetes patient, patient's quantity of intractable hypertension will further increase, and brings great burden for society, family, individual.Present nothing is the intractable hypertension Therapeutic Method preferably, opens up new non-drug therapy means, thereby the deficiency that remedies current pharmacotherapy is simple, it is very urgent safely, effectively to control blood pressure.

Studies confirm that in a large number, the sympathetic nervous system of excessive activation and hypertensive formation are closely related with progress, wherein, the kidney sympathetic nervous system is kidney Sympathetic Nerve and the nervus centripetalis of the most close renal artery wall particularly, the key factor that is considered to the hypertension initiating and keeps.For this mechanism, the foreign scholar has proposed by this new hypertension therapeutic strategy of catheter ablation renal artery sympathetic nerve treatment intractable hypertension.

2009, Krum etc. at first produce the Symplicity ablation catheter with Ardian company 45 routine obstinate hypertension enforcement kidneys are gone the sympathetic nerve radio-frequency ablation procedure in catheter ablation kidney sympathetic nerve treatment intractable hypertension research (Symplicity HTN-1), confirm simple, the safety of this new technique, antihypertensive effect occurs early, and can keep for a long time.In reaching the tracing study in 2 years, find that the blood pressure that descends increases again, and the kidney merit keeps stable.Nearly ten remainders of clinical research that the percutaneous catheter kidney goes sympathetic nerve treatment are being carried out or are being finished at external a plurality of center, finished or ongoing clinical test results encouraging, this technology is expected to become the revolutionary breakthrough in hypertension therapeutic field.

Technique application at home still is in the starting exploratory stage, and this product does not also enter the domestic market, the Fuwai Hospital on February 12nd, 2012 at home through give special approval to Symplicity ablation catheter on probation to 4 routine obstinate hypertension successful implementations operation.Domestic have several hospitals to implement the numerical example kidney in 2011 with the heart radio frequency ablation catheter to go sympathetic nerve treatment, and curative effect has not yet to see bibliographical information.

US 2011/0264075 A1 discloses and has a kind ofly removed orthosympathetic radio frequency ablation catheter for kidney, although this kind conduit that Ardian company produces has certain application in clinical abroad, also has significantly deficiency.At first this kind conduit only can carry out single-point and melts, and generally is to melt around carrying out 6-8 the spiral type of putting in one week of renal artery because kidney removes orthosympathetic radiofrequency ablation therapy, so this kind conduit of Ardian company need to melt 6-8 time, and operating time is long.Ablation catheter for Ardian company can not carry out the problem that multiple spot melts, US 2012/0116392 A1, US 2012/0029510 A1, CN 201110117776.8, thereby CN201110327772.2 arrives the purpose that multiple spot melts simultaneously by radio-frequency ablation electrode is set respectively on many strip electrodes bar, CN 102198015A then realizes that by according to the precalculated position a plurality of radio-frequency electrodes are installed on a spiral electrode stem multiple spot melts simultaneously, although above-mentioned design has realized that to a certain extent multiple spot melts simultaneously in the renal artery, but because radio-frequency ablation electrode and blood vessel wall applying are tight not, so that radio-frequency ablation electrode is mobile easily when melting, and cause ablation range excessive, cause unnecessary damage to the patient; For so that a plurality of radio-frequency ablation electrode attaches simultaneously closely blood vessel wall, US 2012/0101413A1 has adopted the scheme that dilating sacculus is set in revolving the electrode stem of shape, can be so that radio-frequency ablation electrode and blood vessel wall closely attach by in sacculus, being filled with liquid, but the kidney blood flow can be blocked during balloon expandable, cause easily renal ischaemia if the time of melting is grown, and cause unnecessary complication; Be blocked US 2012/0029512 A1 for fear of the kidney blood flow sacculus has been replaced to the tinsel tennis, although solved the problem that the kidney blood flow is blocked, the sacculus that is far from the operation is convenient; It is larger that this stranger's renal artery is walked row variation, and the design of above-mentioned these a plurality of radio-frequency ablation electrodes is difficult to use when the renal artery traveling is morphed, and therefore limited the crowd that kidney goes sympathetic nerve to treat.Secondly the guiding control of the injection of Ardian company frequency electrode catheter and above-mentioned a plurality of frequency ablation electrode catheters is not accurate enough, so that applicable crowd is less than normal, therefore can not finely satisfy clinical requirement.Again, the conduit of the injection of Ardian company frequency electrode catheter and above-mentioned a plurality of radio-frequency ablation electrodes all is difficult to the effect that melts is carried out Real-Time Monitoring, therefore is difficult to carry out examination of curative effect in art, so that patient's second operation risk increases.Ablation catheter in the past mainly adopts the line traffic control structure control, but the line traffic control structure is not easy to operate, and structure is also complicated, the invention provides a kind of conduit control system, and structure is easier.

Summary of the invention

The purpose of this invention is to provide a kind of multiple spot of realizing simultaneously and melted that but Real-Time Monitoring melts barrier effect in the art, the better kidney of mechanical stability goes to sympathetic nerve ablation catheter system

To achieve these goals, the invention provides a kind of ablation catheter system, ablation catheter, guiding catheter, joystick and melt generating means, wherein ablation catheter is comprised of catheter body section and the section of melting from lower to upper successively; Wherein

Described catheter body section links to each other with joystick;

The described section of melting is equipped with absolute construction, and absolute construction is at least two, and the near-end of described absolute construction links to each other, and the described section of melting has at least to be equipped with on the absolute construction and melts head; The described head that melts links to each other with energy exchange joint on the joystick by wire, conduit, microwave antenna or optical fiber, described energy exchange joint by wire, conduit, microwave antenna or optical fiber with melt generating means and link to each other;

Described guiding catheter is by tractive or push an end and be attached on the guiding catheter head end, and the other end is crooked by the guide wire control of handle control; Or the crooked or prefabricated deformation of compliance occurs in described guiding catheter (7).

The far-end of described catheter body section (4) is the controllable bending tune (5) that is connected of the section of comprising and melt (6) near-end also; Also comprise independent the setting or the not independent guiding catheter control handle that arranges.

Further, described ablation catheter or/and guiding catheter or/and the guiding catheter control handle or/and sensor also is installed on the joystick.

Link to each other at near-end between the described absolute construction, comprise three kinds of forms between two absolute construction: the far-end of two absolute construction connects as one and consists of and melt the paragraph header end; Perhaps two absolute construction far-ends are separated from each other independently of one another; Perhaps the mid portion of two absolute construction links together, and far-end is separated from each other again.

When guiding catheter provided fulcrum for ablation catheter deformation, the inclined hole that the head setting of guiding catheter communicates with blood vessel was or/and side channel.

Connect as one when the far-end of absolute construction and consist of when melting the paragraph header end, the guiding catheter head end arranges throat structure or plug, and side channel is set on the head side wall of guiding catheter; When absolute construction is separated from each other independently of one another, on the head end of guiding catheter or the head side wall inclined hole is set.

When the mid portion of absolute construction links together, when far-end was separated from each other again, the inclined hole that the head end of guiding catheter or head side wall setting communicate with blood vessel, inclined hole (74) arranged side channel on the sidewall of guiding catheter afterwards again.

When guiding catheter did not provide fulcrum for ablation catheter deformation, absolute construction arranged prefabricated deformation.

Comprise that also the controllable bending tune arranges prefabricated deformation.

On the described absolute construction or/and also be provided with detecting electrode on the controllable bending tune; Or the described head that melts is used for granting or/and receive electric pulse, melt barrier effect in order to detect, melt head upper, melt on the absolute construction around the head or on the controllable bending tune electric pulse granting can be set or/and collecting electrode, electrode itself can be with the ability of providing and accept electric pulse.For the situation that an electrode is only arranged, preferably electrode is placed that to melt head upper or melt on the absolute construction around the head, melt finish after, place ablation points to lean on the kidney side at electrode, provide suitable electric pulse, if this electric pulse still can cause elevation of the blood pressure, then explanation is melted and is not blocked the kidney sympathetic nerve fully.Situation for a plurality of electrodes, preferably a plurality of electrode gap certain distances are arranged, this moment is except the detection method that melts barrier effect that can adopt when an electrode is only arranged, can also allow at least two electrodes form the electrode pair of accepting and providing electric pulse, by before melting beginning and melt will at least two after finishing the electrode contraposition of electrodes compositions in the both sides, front and back of ablation lesions, by before the ablation relatively and the variation that receives between the electric impulse signal of postoperative electrode also can judge ablation effect, if this signal does not change, illustrate that the kidney sympathetic nerve around the renal artery still can stride across ablation lesions place conduct electrical impulses, namely melts and does not block the kidney sympathetic nerve fully.Above-mentioned two kinds of methods all can be used as and detect kidney and go whether successful method of sympathetic nerve art, and these detection methods help in art in time judgement ablation effect, avoid second operation.In addition the melting head and also can double as providing or/and receive the electrode of electric impulse signal of some type itself, for example radio-frequency ablation electrode head, liquid cooling perfusion radio-frequency electrode are first-class.Certainly the technical staff can not arrange electrode according to the function of ablation catheter yet.When a plurality of electrode is set, can be respectively provided to few electrode at the absolute construction that melts the head front and back, perhaps at least one electrode can be arranged on melt head upper, melt on the absolute construction around the head and other electrode be arranged on the place that the controllable bending tune contact with renal artery, or will melt as the granting of electric impulse signal or collecting electrode and be arranged on electrode on the absolute construction that melts on every side or place that the controllable bending tune contacts with renal artery.The shape of electrode can be various, for example can be that ring-type holds absolute construction, also can be semicircular, only holds the part that absolute construction contacts with blood vessel, the little point-like of all right projection; In any case but the shape of electrode should help it to contact with blood vessel.Electrode preferably passes to the signal that receives on the joystick by the wire in the ablation catheter, and preferably finally passes to and melt generating means.

Also be provided with on the afterbody sidewall of described guiding catheter for connecting syringe or priming device and carry out the perforate of injection in the blood vessel or injection Intravascular contrast agents, or carry out blood vessel in injection or/and inject Intravascular contrast agents with syringe or/and priming device links to each other by the guiding catheter end openings; Or/and described guiding catheter end arranges jointing, jointing is connected with syringe, priming device, ablation catheter or joystick.

Described ablation catheter or/and guiding catheter when making by selecting the material of different hardness, or by optionally reducing or/and increase the internal structure of catheter segment or/and the structure of tube wall.

Described ablation catheter is or/and reference mark on the guiding catheter, with the indication ablation catheter or/and the degree of depth of guiding catheter intravasation and length, the width of under ultrasonic or X ray image equipment, indirectly measuring organization of human body; Ablation catheter is used for distinguishing ablation catheter or/and guiding catheter or/and different developing marks is set on the guiding catheter under ultrasonic or X ray image equipment; Or/and being set on each absolute construction, different developing marks is used under ultrasonic or X ray image equipment, distinguishing different absolute construction; Ablation catheter is used for distinguishing different axial-rotation states or/and labelling also is set on the guiding catheter under ultrasonic or X ray image equipment.

The end of ablation catheter is or/and guiding catheter and joystick upper end is fixing, and ablation catheter links to each other with connecting rod on the annular control knob; The lower end of joystick or downside have the energy exchange joint, and the center cavity that passes joystick from the wire, conduit, microwave antenna or the optical fiber that melt head compiles at described energy exchange joint.

Ablation catheter is fixing by catheter body section and joystick upper end, and the lower end of joystick or downside have the energy exchange joint, passes joystick from the wire, conduit, microwave antenna or the optical fiber that melt head and compiles at described energy exchange joint.

Be provided with control knob or console panel for the deformation of control guiding catheter on the described joystick, described control knob or console panel are connected with guide wire, by moving up and down of control knob, or pass through the multiple-directional rotating realization of console panel to the control of controllable bending tune; Or/and annular control knob, described annular control knob is connected with traction fiber by connecting rod, and described connecting rod is arranged in the gathering sill of joystick, by moving up and down annular control knob, realizes the control to absolute construction; Also comprise the buffer structure that can prevent excessive tractive.

Be provided with control knob or console panel for the deformation of control guiding catheter on the described guiding catheter control handle, described control knob or console panel are connected with guide wire, by moving up and down of control knob, or pass through the multiple-directional rotating realization of console panel to the control of guiding catheter; Described guiding catheter control handle and joystick comprise can take off groove tooth slide construction, formed by draw-in groove, cone cylinder groove, snap ring, hole clipping pressure hook shape structure and the outstanding tenon of cone cylinder but can take off groove tooth slide construction, break and combination by taking off groove tooth slide construction.

The described generating means that melts is provided with the joint of energy output and the joint of sensor signal input, also is provided with simultaneously and external power supply phase ground joint; Described melt generating means contain by carry out touch screen control parameter and partly or entirely information can show thereon display and the button of adjusting parameter.

The invention provides and a kind ofly realize that simultaneously but multiple spot melts on-line real time monitoring and melts barrier effect, conduit and make relatively simple, the better kidney of mechanical stability and go to sympathetic nerve ablation catheter system.

Because having adopted all can arrange at least two absolute construction and every the absolute construction, the present invention melts head, therefore can realize that multiple spot melts simultaneously, shortened the time of melting, and then reduced operating time, reduced patient's misery, in addition since when melting melting head and will contact with blood vessel wall simultaneously on many absolute construction, can prevent from melting head slides, so that melt when melting add first watch stable, when having prevented from melting because melting a unnecessary damage of the unstable normal structure that causes, reduced the complication that melts generation, made ablation procedure safer.In addition, guiding catheter has corresponding line traffic control structure that its deformation is controlled, therefore conduit has handling preferably, the renal artery that can adapt to different travelings, and ablation catheter adds the cover guiding catheter and assist ablation catheter to locate, whole like this ablation catheter system will be more accurate in endovascular location, prevent unnecessary damage, also can make whole ablation system be applied to more crowd simultaneously.Ablation catheter has been avoided complicated line traffic control structure in this design in addition, makes its structure more easy.Moreover, for convenience Real-Time Monitoring ablation effect in operation, detecting electrode also is installed with the convenient ablation effect that in time detects on ablation catheter, avoids the second operation risk.

Description of drawings

Fig. 1 is the sketch map according to an embodiment of the invention major part.

Fig. 2 is the sketch map of the connected mode between two absolute construction in the section of melting of amplifying.

Fig. 3 is the sketch map after under the different connected modes deformation occuring between two absolute construction in the section of melting of amplifying.

Fig. 4 is the sketch map of radio-frequency ablation electrode head different set-up mode on absolute construction.

Fig. 5 is the sketch map of radio-frequency ablation electrode head when being the radio-frequency ablation electrode head.

Fig. 6 is the sketch of absolute construction section of melting when being two.

Fig. 7 is the sketch of absolute construction section of melting when being three.

Fig. 8 is the sketch of absolute construction section of melting when being four.

Fig. 9 is that absolute construction is three and the sketch under the duty when being separated from each other.

Figure 10 is the cross-sectional profiles sketch of absolute construction when being two to four.

Sketch map when Figure 11 is the controllable bending tune for the design of " C " shape under the duty.

Figure 12, Figure 13, Figure 14, Figure 15 are as an example of two absolute construction example and guiding catheter can provide in the situation of fulcrum the sketch map of guiding catheter head as the deformation of ablation catheter.

Figure 16 be take far-end be connected in melt the paragraph header end two absolute construction in the situation of example, the sketch map under the sketch map of guiding catheter head and ablation catheter and the guiding catheter duty

Figure 17, Figure 18 are the sketch maps that changes ablation catheter and the distribution of guiding catheter hardness by the mode of structural design.

Figure 19 is the sketch map that is connected in the hardness distribution realization design deformation of the absolute construction that melts the paragraph header end by adjusting far-end.

Figure 20 distributes by the hardness of adjusting the controllable bending tune to realize the sketch map of design deformation.

Figure 21 is that the hardness of the absolute construction that is separated from each other by adjustment distributes and realizes the sketch map of design deformation.

Figure 22, Figure 23 distribute and realize the sketch map of design deformation by the link together hardness of the absolute construction that far-end is separated from each other again of somewhere in the middle of adjusting.

Figure 24 is the sketch map of guiding catheter afterbody primary structure.

Figure 25 is the line traffic control structure of guiding catheter and the sketch map that forms needed deformation form by chicken ribs spline structure promotion guiding catheter.

Figure 26, Figure 27 and Figure 28 are in the situation as an example of the line traffic control structure example, the sketch map of the main structure of several dissimilar joysticks.

The specific embodiment

Below in conjunction with the drawings and specific embodiments, further set forth embodiments of the invention.These embodiment are interpreted as only being used for the explanation embodiments of the invention and are not used in the protection domain that limits embodiments of the invention.After the content of having read the embodiments of the invention records, the technical staff can be used for various modifications or revise embodiments of the invention, and these equivalences change and modification falls into embodiments of the invention claim limited range equally.

Fig. 1 has shown parts main in the specific embodiment of the present invention.As shown in Figure 1, this kind kidney goes the sympathetic nerve ablation system mainly by ablation catheter 1, guiding catheter 7, joystick 2 and melt generating means 3 and form, and according to circumstances arranges or do not arrange guiding catheter control handle 27.As shown in Figure 1, ablation catheter 1 far-end (head end) is free, near-end (tail end, end) links to each other with joystick 2, ablation catheter 1 is comprised of catheter body section 4 and the section of melting 6 to far-end successively at least near-end, wherein the near-end of catheter body section 4 (tail end, end) links to each other with joystick 2, the far-end of the section of melting 6 (head end) is free, and catheter body section front end also can comprise controllable bending tune 5, and other section according to circumstances also can be set between catheter body section 4 and the section of melting 6.Preferably, the outline of ablation catheter 1 each section cross section preferably adopts circle or similar round, and it is preferably close or equal that ablation catheter 1 enters into endovascular each section diameter.The length of ablation catheter 1 must be so that the section of melting 6 can arrive the ablation site of bilateral renal arteries appointment smoothly, be generally 50--120cm, and the maximum gauge of whole ablation catheter 1 each section preferably less than must be through the minimum diameter of blood vessel path medium vessels, the diameter of ablation catheter 1 is generally 1.4--2.5mm.As shown in Figure 1, wherein guiding catheter 7 is preferably hollow tubular structure, and the head and the tail two ends are equipped with opening, and guiding catheter 7 is enclosed within the ablation catheter 1 outer ablation locations that can assist ablation catheter 1 to arrive appointment.The length of guiding catheter 7 must be so that guiding catheter 7 can successfully guide ablation catheter 1 to arrive the ablation site of bilateral renal arteries appointment, be generally 50--120cm, and the maximum outside diameter of whole guiding catheter 7 each sections preferably less than must be through the minimum diameter of blood vessel path medium vessels, the diameter of guiding catheter 7 is generally 1.4--2.5mm.

Fig. 2 has shown the main feature of the section of melting 6 in the embodiments of the invention.As shown in Figure 2, the section of melting 6 is comprised of at least two absolute construction 8; This absolute construction 8 can be cylinder shape, similar cylinder shape, half round post, cone-shaped, similar cone-shaped, arc etc., the length of each absolute construction 8 and cross sectional dimensions can equate also can not wait, but preferably, the outline of the section of melting 6 cross sections that surround of the outline of all absolute construction 8 cross sections is preferably near the outline of controllable bending tune 5 cross sections.Shown in Fig. 2 A, the far-end of two absolute construction 8 (head end) is connected in and melts paragraph header end 17 (also being the ablation catheter head end); Shown in Fig. 2 B, two absolute construction 8 are separated from each other, independently of one another; Shown in Fig. 2 C, the middle somewhere of two absolute construction 8 far-end that links together is separated from each other again, and wherein junction point 18 is described two places that absolute construction 8 links together.The tail end of absolute construction 8 is connected in the controllable bending tune 5 of catheter body section 4 front ends.

Fig. 3 has shown the situation of absolute construction 8 after under two different connected modes deformation occuring in the embodiments of the invention.Wherein Fig. 3 A has shown that far-end is connected in the situation after deformation occur the absolute construction 8 that melts paragraph header end 17, this moment absolute construction 8 the mid portion protuberance that will scatter, usually, with the centre of absolute construction 8 or swell the most obvious near middle place.Fig. 3 B has shown when absolute construction 8 is separated from each other situation about occuring after the deformation, this moment absolute construction 8 will be mutually away from, usually, with the head end of absolute construction 8 and near position thereof mutually away from the most obvious.Fig. 3 C has shown that somewheres in the middle of the absolute construction 8 link together situation after the deformation has occured when far-end is separated from each other again, this moment 8 head ends from junction point 18 to absolute construction part will be mutually away from, usually, with absolute construction 8 head ends and near position thereof mutually away from the most obvious, part 8 tail ends from junction point 18 to absolute construction (terminal, the far-end) protuberance that will scatter, usually, arrive the centre of the part between absolute construction 8 tail ends or swell the most obvious near middle place with junction point 18.

Fig. 4 has shown the different set-up mode on the absolute construction 8 of radio-frequency ablation electrode head 9 in the embodiments of the invention.Shown in Fig. 4 A, have at least on the absolute construction 8 to be provided with radio-frequency ablation electrode head 9; Shown in Fig. 4 B, Fig. 4 C, each absolute construction 8 can arrange not only radio-frequency ablation electrode head 9.Radio-frequency ablation electrode head 9 is mainly used in melting blocking-up to kidney is orthosympathetic; Radio-frequency ablation electrode head 9 should be the original paper of performance ablation, and preferred radio-frequency ablation electrode head 9 is the radio frequency electrical cartridge,

Fig. 5 A-C is that the far-end take two absolute construction 8 is connected in and melts paragraph header end 17 as example, shown the main structure of radio-frequency (RF) ablation 9.Fig. 5 A has shown the main structure under the vertical section, and the radio-frequency ablation electrode head comprises radio-frequency ablation electrode 91, and preferably, radio-frequency ablation electrode 91 slightly protrudes from the surperficial 0.05--0.2mm of absolute construction 8, in order to contact with blood vessel wall.Shown in Fig. 5 A, the radio frequency wire 101 of traveling in absolute construction 8 will link to each other with the radio-frequency ablation electrode utmost point 91, and for radio-frequency ablation electrode 91 provides energy, wire junction point 191 is link positions of radio frequency wire 101 and radio-frequency ablation electrode 91.Shown in Fig. 5 A, holding wire 102 be arranged on radio-frequency ablation electrode 91 on or/and the sensor 192 of contiguous radio-frequency ablation electrode 91 links to each other, be used for the signal of transmission sensor 192 (Fig. 5 B shows) transmission; Sensor 192 can be dissimilar, such as: temperature sensor, impedance transducer, pressure transducer etc.; The sensor 192 of same type also can more than one (Fig. 5 be as example with a sensor 192) on absolute construction 8; The parameter monitoring of 192 pairs of radio-frequency ablation electrodes 91 of sensor and human body helps to understand real-time condition, in time adjusts therapeutic scheme.Fig. 5 B and Fig. 5 C have shown radio-frequency ablation electrode head 9 and the main structure of absolute construction 8 on every side thereof with perspective fashion.Shown in Fig. 5 B, radio-frequency ablation electrode 91 (the figure bend represents part) can only hold the bent side of semicylinder and not hold the flat side 90 of semicylinder; Shown in Fig. 5 C, the bent side that radio-frequency ablation electrode 91 (the figure bend represents part) can both hold semicylinder also holds the flat side 90 of semicylinder; Certainly radio-frequency ablation electrode 91 also can according to circumstances be adjusted its scope that holds.Fig. 5 D, Fig. 5 E are that the far-end with two absolute construction 8 is separated from each other as example, have shown the main structure in radio-frequency (RF) ablation 9 vertical section; Wherein, Fig. 5 D shows is to melt 9 situations that hold the bent side of semicylinder and do not hold the flat side 90 of semicylinder, and Fig. 5 E shows is to melt 9 situations that hold the flat side 90 of the bent side of semicylinder and semicylinder.The design of the radio-frequency ablation electrode head that the design of the radio-frequency ablation electrode head that Fig. 5 D, Fig. 5 E illustrate and Fig. 5 A-C illustrate is similar.Shown in Fig. 5 D, Fig. 5 E, the far-end of absolute construction 8 can be mutually away from, similarly, the radio frequency wire 101 of traveling in absolute construction 8 will link to each other with radio-frequency ablation electrode 91, for radio-frequency ablation electrode head 9 provides energy, wire junction point 191 is positions that radio frequency wire 101 is connected with radio-frequency ablation electrode 91.Shown in Fig. 5 D, Fig. 5 E, similarly, holding wire 102 be arranged on radio-frequency ablation electrode 91 on or/and the sensor 192 of contiguous radio-frequency ablation electrode 91 links to each other, be used for the signal of transmission sensor 192 transmissions; Similarly, sensor 192 can be dissimilar, such as: temperature sensor, impedance transducer, pressure transducer etc.; The sensor 192 of same type also can more than one (Fig. 8 be as example with a sensor 192) on absolute construction 8; The parameter monitoring of 192 pairs of radio-frequency ablation electrode heads 9 of sensor and human body helps to understand real-time condition, in time adjusts therapeutic scheme.Shown in Fig. 5 D, radio-frequency ablation electrode 91 can only hold the bent side of semicylinder and not hold the flat side 90 of semicylinder; Shown in Fig. 5 E, the bent side that radio-frequency ablation electrode 91 can both hold semicylinder also holds the flat side 90 of semicylinder; Certainly radio-frequency ablation electrode 91 also can according to circumstances be adjusted its scope that holds absolute construction 8.Fig. 5 only is that the far-end take two absolute construction 8 is connected in and melts paragraph header end 17 and far-end and be separated from each other the design explanation of carrying out radio-frequency (RF) ablation 9 as example, and therefore the design of radio-frequency (RF) ablation illustrated in Figure 59 is equally applicable to other connected modes of absolute construction 8 and the situation of a plurality of absolute construction 8; For semi-cylindrical situation and for melting a situation that the shape of the absolute construction at 9 setting position places 8 changes to some extent, also can copy design illustrated in Figure 5 to design for the shape of absolute construction 8.

Fig. 6, Fig. 7, Fig. 8 be the simple main structure that has shown the section of melting 6 when absolute construction 8 is two to four respectively.It is three and the situation under the duty when being separated from each other that Fig. 9 has enumerated absolute construction 8.The cross-sectional profiles when absolute construction 8 is two to four has been shown in Figure 10 letter.

As shown in Figure 6, when absolute construction 8 was two, preferably each absolute construction 8 was provided with a radio-frequency ablation electrode head 9.As shown in Figure 6A, the far-end of two absolute construction 8 is connected in and melts paragraph header end 17, two absolute construction 8 preferably wait greatly, each absolute construction 8 length is preferably 13--30mm, the deformation of two absolute construction 8 is incited somebody to action so that the mid portion of two absolute construction 8 swells relatively, form similar fusiform structure, the most obvious place of protuberance generally is positioned at the centre of absolute construction 8 or also will at first contacts blood vessel wall near middle position, and radio-frequency ablation electrode head 9 preferably is arranged at each the most obvious place of absolute construction 8 protuberances at this moment; Each the most obvious place of absolute construction 8 protuberances can be different; The most obvious partial-length of median rise of each absolute construction 8 can be different, and this moment, radio-frequency ablation electrode head 9 can be on the same cross section or not on same cross section at the setting position of each absolute construction 8.Shown in Fig. 6 B, two absolute construction 8 are separated from each other, the length of two absolute construction 8 preferably equates, each absolute construction 8 length is preferably 10--20mm, the deformation of two absolute construction 8 will so that two absolute construction 8 mutually away from, away from the most also will at first contacting blood vessel wall, radio-frequency ablation electrode head 9 is preferably disposed on head end and near the position thereof of each absolute construction 8 at this moment mutually for the head end of general absolute construction 8 and near position thereof; If wish ablation points on the varying cross-section of blood vessel, can make the length of two absolute construction 8 unequal, the perhaps equal in length of two absolute construction 8, but radio-frequency ablation electrode head 9 is different at the setting position of each absolute construction 8 head.Shown in Fig. 6 C, the middle somewhere of two absolute construction 8 far-end that links together is separated from each other again, the length of two absolute construction 8 preferably equates, the length of each absolute construction 8 is preferably 20--40mm, and junction point 18 preferably is chosen in absolute construction 8 far-ends account for whole absolute construction 8 length 30--50% to the part of junction point 18 place; Shown in Fig. 6 C, the deformation of two absolute construction 8 is incited somebody to action so that junction point 18 swells relatively to the part of absolute construction 8 tail ends, generally so that protuberance is the most obvious relatively in the middle of this part or near middle position, and junction point 18 to the part of absolute construction 8 head ends mutually away from, generally with the head end of absolute construction 8 and near position thereof mutually away from the most obvious, to have four positions preferentially to contact blood vessel wall this moment, namely the head end of two absolute construction 8 and near position thereof and the protuberance the most obvious place, preferably radio-frequency ablation electrode head 9 is arranged at head end and near the position thereof of two absolute construction 8, and electrode 19 can be arranged on the most obvious place of median rise; If wish that ablation points is on the varying cross-section of blood vessel, can make in two absolute construction 8 junction point 18 unequal to the partial-length between absolute construction 8 head ends, the perhaps equal in length of two absolute construction 8, junction point 18 to the length of the absolute construction 8 between absolute construction 8 tail ends also equates, but radio-frequency ablation electrode head 9 is not identical at the setting position of each absolute construction 8 head.

As shown in Figure 6, when absolute construction 8 was two, preferably each absolute construction 8 was provided with a radio-frequency (RF) ablation 9.As shown in Figure 6A, the far-end of two absolute construction 8 is connected in and melts paragraph header end 17, two absolute construction 8 preferably wait greatly, each absolute construction 8 length is preferably 13--16mm, the deformation of two absolute construction 8 is incited somebody to action so that the mid portion of two absolute construction 8 swells relatively, form similar fusiform structure, the most obvious place of protuberance generally is positioned at the centre of absolute construction 8 or near middle position and will at first contact blood vessel wall, and this moment, radio-frequency (RF) ablation 9 preferably was arranged at each the most obvious place of absolute construction 8 protuberances; The most obvious place of each absolute construction 8 protuberances can different (shown in similar Figure 19 B); The most obvious partial-length of median rise of each absolute construction 8 can different (shown in similar Figure 19 D), and this moment, radio-frequency (RF) ablation 9 can be on the same cross section or not on same cross section at the setting position of each absolute construction 8.Shown in Fig. 6 B, two absolute construction 8 are separated from each other, the length of two absolute construction 8 preferably equates, each absolute construction 8 length is preferably 10--6mm, the deformation of two absolute construction 8 will so that two absolute construction 8 mutually away from, the head end of general absolute construction 8 and near position thereof be mutually away from the most obviously and will at first contact blood vessel wall, and this moment, radio-frequency (RF) ablation 9 was preferably disposed on head end and near the position thereof of each absolute construction 8; If wish that ablation points is on the varying cross-section of blood vessel, can make the length of two absolute construction 8 unequal (shown in similar Figure 21 B), the perhaps equal in length of two absolute construction 8, but radio-frequency (RF) ablation 9 is at the setting position of each absolute construction 8 head different (shown in similar Figure 21 C).Shown in Fig. 6 C, the middle somewhere of two absolute construction 8 far-end that links together is separated from each other again, the length of two absolute construction 8 preferably equates, the length of each absolute construction 8 is preferably 6--26mm, and junction point 18 preferably is chosen in absolute construction 8 far-ends account for whole absolute construction 8 length 16--26% to the part of junction point 18 place; Shown in Fig. 6 C, the deformation of two absolute construction 8 is incited somebody to action so that junction point 18 swells relatively to the part of absolute construction 8 tail ends, generally so that protuberance is the most obvious relatively in the middle of this part or near middle position, and junction point 18 to the part of absolute construction 8 head ends mutually away from, generally with the head end of absolute construction 8 and near position thereof mutually away from the most obvious, to have four positions preferentially to contact blood vessel wall this moment, namely the head end of two absolute construction 8 and near position thereof and the protuberance the most obvious place, preferably radio-frequency (RF) ablation 9 is arranged at head end and near the position thereof of two absolute construction 8, and detecting electrode 19 can be arranged on the most obvious place of median rise; If wish that ablation points is on the varying cross-section of blood vessel, can make in two absolute construction 8 junction point 18 to the partial-length between absolute construction 8 head ends unequal (shown in similar Figure 23 B), the perhaps equal in length of two absolute construction 8, junction point 18 to the length of the absolute construction 8 between absolute construction 8 tail ends also equates, but radio-frequency (RF) ablation 9 setting position not identical (shown in similar Figure 23 C) at each absolute construction 8 head.

As shown in Figure 7, when absolute construction 8 was three, preferably each absolute construction 8 was provided with a radio-frequency ablation electrode head 9.Shown in Fig. 7 A, the far-end of three absolute construction 8 is connected in and melts paragraph header end 17, three absolute construction 8 preferably wait greatly, the length of each absolute construction 8 is preferably 13--30mm, the deformation of three absolute construction 8 is with the protuberance so that the mid portion of three absolute construction 8 scatters, form similar fusiform structure, the most obvious place of protuberance generally is positioned at the centre of absolute construction 8 or also will at first contacts blood vessel wall near middle position, the most obvious place of mid portion protuberance of each absolute construction 8 is preferably different, and radio-frequency ablation electrode head 9 is preferably disposed on the most obvious place of protuberance at this moment; Perhaps the most obvious partial-length of median rise of each absolute construction 8 is different, and the setting position of radio-frequency ablation electrode head 9 on each absolute construction 8 be not preferably on same cross section at this moment.Shown in Fig. 7 B, three absolute construction 8 are separated from each other, the length of absolute construction 8 is preferably 10--20mm, the deformation of three absolute construction 8 will so that three absolute construction 8 mutually away from, generally with the head end of absolute construction 8 and near position thereof mutually away from the most obvious, radio-frequency ablation electrode head 9 is preferably disposed on head end and near the position thereof of each absolute construction 8 at this moment, the length of three absolute construction 8 can not wait, because the length of three absolute construction 8 is different, therefore each radio-frequency ablation electrode head 9 at first contacts the position of blood vessel wall also not on same cross section, as shown in Figure 9, the position of radio-frequency ablation electrode head 9 contact renal artery d lays respectively at a, b, on three different cross sections of c; The perhaps equal in length of three absolute construction 8, but radio-frequency ablation electrode head 9 is different at the setting position of each absolute construction 8 head.The middle somewhere of three absolute construction 8 far-end that links together is separated from each other again, junction point 18 preferably is chosen in the longest absolute construction 8 far-ends account for the longest whole absolute construction 8 length 30--50% to the part of junction point 18 place, preferably, each absolute construction 8 length is 20--40mm; Shown in Fig. 7 C, for so that ablation points not on the same cross section of blood vessel, the length of three absolute construction 8 can not wait, but junction point 18 to the partial-length between absolute construction 8 tail ends preferably equates, the deformation of three absolute construction 8 will so that on three absolute construction 8 junction point 18 to the part of the absolute construction 8 tail ends protuberance that scatters, generally so that protuberance is the most obvious relatively in the middle of this part or near middle position, and junction point 18 to the part of absolute construction 8 head ends mutually away from, generally with the head end of absolute construction 8 and near position thereof mutually away from the most obvious, to have six positions preferentially to contact blood vessel wall this moment, the i.e. head end of three absolute construction 8 and near position thereof and the most obvious place of protuberance, this moment, radio-frequency ablation electrode head 9 was preferably disposed on head end and near the position thereof of absolute construction 8; The perhaps equal in length of three absolute construction 8, junction point 18 to the partial-length between absolute construction 8 tail ends equate that also this moment, radio-frequency ablation electrode head 9 was different at the setting position of each absolute construction 8 head; Shown in Fig. 7 C, junction point 18 to protuberance between absolute construction 8 tail ends the most obviously can arrange electrode 19.

As shown in Figure 8, when absolute construction 8 is four, preferably on each absolute construction 8 a radio-frequency ablation electrode head 9 is set.Shown in Fig. 8 A, the far-end of four absolute construction 8 is connected in and melts paragraph header end 17, four absolute construction 8 preferably wait greatly, the length of each absolute construction 8 is preferably 13--30mm, the deformation of four absolute construction 8 is with the protuberance so that the mid portion of four absolute construction 8 scatters, form similar fusiform structure, the most obvious place of protuberance generally is positioned at the centre of absolute construction 8 or also will at first contacts blood vessel wall near middle position, the most obvious place of mid portion protuberance of each absolute construction 8 is preferably different, and radio-frequency ablation electrode head 9 is preferably disposed on the most obvious place of protuberance at this moment; Perhaps the most obvious partial-length of median rise of each absolute construction 8 is different, and the setting position of radio-frequency ablation electrode head 9 on each absolute construction 8 be not preferably on same cross section at this moment.Shown in Fig. 8 B, four absolute construction 8 are separated from each other, the length of absolute construction 8 is preferably 10--20mm, the deformation of four absolute construction 8 will so that four absolute construction 8 mutually away from, generally with the head end of absolute construction 8 and near position thereof mutually away from the most obvious, the length of four absolute construction 8 can not wait, radio-frequency ablation electrode head 9 preferably is arranged on head end and near the position thereof of absolute construction 8 at this moment, because the length of four absolute construction 8 is different, so each radio-frequency ablation electrode head 9 at first contacts the position of blood vessel wall also not on same cross section; The perhaps equal in length of four absolute construction 8, but radio-frequency ablation electrode head 9 is different at the setting position of each absolute construction 8 head.Shown in Fig. 8 C, the middle somewhere of four absolute construction 8 far-end that links together is separated from each other again, junction point 18 preferably is chosen in the longest absolute construction 8 far-ends account for the longest whole absolute construction 8 length 30--50% to the part of junction point 18 place, preferably, each absolute construction 8 length is 20--40mm; Shown in Fig. 8 C, for so that ablation points not on the same cross section of blood vessel, the length of four absolute construction 8 can not wait, but junction point 18 to the partial-length between absolute construction 8 tail ends preferably equates, the deformation of four absolute construction 8 will so that on four absolute construction 8 junction point 18 to the part of the absolute construction 8 tail ends protuberance that scatters, generally so that protuberance is the most obvious relatively in the middle of this part or near middle position, and junction point 18 to the part of absolute construction 8 head ends mutually away from, generally with the head end of absolute construction 8 and near position thereof mutually away from the most obvious, to have eight positions preferentially to contact blood vessel wall this moment, the i.e. head end of four absolute construction 8 and near position thereof and the most obvious place of protuberance, this moment, radio-frequency ablation electrode head 9 was arranged on head end and near the position thereof of absolute construction 8; The perhaps equal in length of four absolute construction 8, junction point 18 to the partial-length between absolute construction 8 tail ends equate that also this moment, radio-frequency ablation electrode head 9 was different at the setting position of each absolute construction 8 head; Shown in Fig. 8 C, junction point 18 to protuberance between absolute construction 8 tail ends the most obviously can arrange electrode 19.Shown in Fig. 8 D, have two relative absolute construction 8 to be separated from each other in four absolute construction 8, and the far-end of two other relative absolute construction 8 is connected in and melt paragraph header end 17, preferably, the length of each absolute construction 8 is 13--30mm; Shown in Fig. 8 D, being connected in two absolute construction 8 that melt paragraph header end 17 for far-end preferably waits greatly, the deformation of these two absolute construction 8 is incited somebody to action so that their mid portion swells relatively, the most obvious place of protuberance generally is positioned at the centre of these two absolute construction 8 or also will at first contacts blood vessel wall near middle position, the most obvious place of mid portion protuberance of these two absolute construction 8 is preferably different, radio-frequency ablation electrode head 9 preferably is arranged on the most obvious place of protuberance, perhaps the most obvious partial-length of median rise of these two absolute construction 8 is different, and the setting position of radio-frequency ablation electrode head 9 on these two absolute construction 8 be not preferably on same cross section at this moment; Shown in Fig. 8 D, can be different for two absolute construction 8 length that are separated from each other, the deformation of these two absolute construction 8 will so that they mutually away from, generally with the head end of these two absolute construction 8 and near position thereof mutually away from the most obvious, radio-frequency ablation electrode head 9 preferably is arranged on head end and near the position thereof of these two absolute construction 8, the perhaps equal in length of these two absolute construction 8, and radio-frequency ablation electrode head 9 is different at the setting position of these two absolute construction 8 heads; Above-mentioned design is the most at last so that four radio-frequency ablation electrode heads 9 contact the position of blood vessel wall on mutually different cross section.Shown in Fig. 8 E, the far-end of four not isometric absolute construction 8 is connected in the different parts of traction fiber 10, and preferably, the length of absolute construction 8 is 13--30mm, the major axis central lines of traction fiber 10 and ablation catheter 1; When deformation occurs in four absolute construction 8 under the effect of traction fiber 10, the mid portion of each absolute construction 8 protuberance that will scatter, the most obvious place of protuberance will at first contact blood vessel wall, because absolute construction 8 is not isometric and the fixed position on traction fiber is different, therefore the most obvious place of protuberance also can be different, like this radio-frequency ablation electrode head 9 are arranged on these the most obvious places of protuberance and just guaranteed that ablation points is not on arteriorenal same cross section.The cross section outline of the section of melting 6 is preferably similar to the cross section outline of controllable bending tune 5 in addition, each absolute construction 8 compact arranging as far as possible in the outline scope of the section of melting 6, as shown in figure 10, when absolute construction 8 was two to four, each absolute construction 8 is preferably in divided circle equally on the cross section.Certainly along with the increase of absolute construction 8 quantity, the cross-sectional profiles of absolute construction 8 also can adopt other designs so that compact the arranging of trying one's best in the outline scope of the section of melting 6 of each absolute construction 8.Continue the situation of increase for absolute construction 8 quantity, preferably adopt following design, be the far-end of each absolute construction 8 can be connected in melt paragraph header end 17, each absolute construction 8 is separated from each other and the far-end of not isometric absolute construction 8 is connected in the different parts of traction fiber 10, corresponding design that these designs can be copied absolute construction 8 when being three and four.

The Main Function that controllable bending tune 5 is set is to help the section of melting 6 to arrive more easily the ablation locations of appointment, such as so that the easier bending by blood vessel of the section of melting 6 so that the section of melting 6 is easier of assigned direction deflection etc.Cylindrical or the class cylinder design of controllable bending tune 5 preferred employings, different according to the length of different design controllable bending tunes 5.Situation when Figure 11 has shown controllable bending tune 5 for " C " shape curved design under the duty, Figure 25 is that the absolute construction 8 of the section of melting 6 describes when being two, and when be other design forms for the section of melting 6, a needs replacement section of melting 6 gets final product.As shown in figure 11, be shaped as " C " shape after 5 deformation of controllable bending tune, the controllable bending tune 5 of solid line part has represented the situation of a kind of " C " shape bending, under this shape, controllable bending tune 5 preferred lengths are 60--120mm, controllable bending tune 5 will have two local c1 to contact with the blood vessel medial wall with c2, wherein c1 contacts with the medial wall of renal artery a, and c2 contacts with the medial wall of ventral aorta b, be conducive to like this when melting, stablize radio-frequency ablation electrode head 9, controllable bending tune 5 this moment preferably and one of them absolute construction 8 at grade, like this for only have on the absolute construction 8 radio-frequency ablation electrode head 9 as the electric pulse granting or/and the situation of collecting electrode, can electrode 19 be set at c1, electrode 19 on electrode on radio-frequency ablation electrode head 9 or the absolute construction 8 19 and the controllable bending tune 5 will form one and provide electric pulse like this, one receives electric pulse, certainly for adapting to the renal artery of different tube diameters, a plurality of ring-type collecting electrodes 19 can be set near c1; As shown in figure 11, the controllable bending tune 5 of dotted portion has represented another kind " C " situation of shape bending, in this case, controllable bending tune 5 preferred lengths are 40--100mm, controllable bending tune 5 can not contact with the medial wall of tremulous pulse, perhaps only there is a local c2 to contact with the medial wall of tremulous pulse, so the stable strong point that will mainly rely on each absolute construction 8 to contact with the medial wall of tremulous pulse and form of radio-frequency ablation electrode head 9.

As the case may be, the technical staff can be merged the design of above-mentioned these sections of melting 6 and controllable bending tune 5, improvement and cross-reference, and these equivalences change and modify and fall into equally embodiments of the invention claim limited range.

Described controllable bending tune 5, absolute construction 8 and guiding catheter 7 can have prefabricated deformation, and for example as shown in figure 11, it is crooked in advance controllable bending tune 5 to be preset to " C " shape when external manufacturing, so that the section of melting 6 can enter renal artery smoothly.The technical staff can be implemented in and external prefabricated deformation adjusted by add the material with shape memory function in controllable bending tune 5, absolute construction 8 and guiding catheter 7, for example: in controllable bending tune 5, add marmem, it is crooked first it to be made " C " shape in advance at external bending shape, when needs controllable bending tune 5 changes bending shape, can again it be taken out the external curved pattern of controllable bending tune 5 being made other shapes by variations in temperature again.

The Main Function of described guiding catheter 7 is to be enclosed within ablation catheter 1 to play guiding ablation catheter 1 direction outward, hold ablation catheter 1 and provide passage for ablation catheter 1, therefore the internal diameter of guiding catheter 7 is because of bigger than ablation catheter 1 external diameter, and guiding catheter 7 can also play the effect that fulcrum is provided for the deformation of ablation catheter 1 sometimes in addition.Figure 12, Figure 13, Figure 14, Figure 15 are take two absolute construction 8 as example, have shown that guiding catheter 7 can provide in the situation of fulcrum the main structure of guiding catheter 7 heads for the deformation of ablation catheter 1; Wherein Figure 12 shows is the main structure of absolute construction 8 guiding catheter 7 heads when being separated from each other, Figure 13 shows is absolute construction 8 situation under guiding catheter 7 and absolute construction 8 duties when being separated from each other, Figure 14 shows is the main structure that the far-end of absolute construction 8 is connected in guiding catheter 7 heads when melting paragraph header end 17, and Figure 15 shows is the link together main structure of far-end guiding catheter 7 heads when being separated from each other again of somewheres in the middle of the absolute construction 8.Figure 16 be take far-end be connected in melt paragraph header end 17 two absolute construction 8 as example, shown guiding catheter 7 not for the deformation of ablation catheter 1 provides in the situation of fulcrum, the main structure of guiding catheter 7 heads.

The inclined hole 74 that can provide for the deformation of ablation catheter 1 situation of fulcrum, the head of guiding catheter 7 preferably to arrange to communicate with blood vessel for guiding catheter 7 is or/and side channel 76.The passage that inclined hole 74 and side channel 76 stretch out outside guiding catheter 7 mainly as absolute construction 8 realizes that absolute construction 8 contacts with blood vessel wall, and certain inclined hole 74 and side channel 76 also can be used as in the blood vessel injection or/and the passage of injection of contrast medium.The set-up mode that interconnects the inclined hole 74 of different guiding catheters 7 heads of mode and side channel 76 according to absolute construction 8 quantity and absolute construction 8 in twos is also different.Figure 12 A, Figure 12 B, Figure 12 C are the vertical section sketch map, and Figure 12 D, Figure 12 E are perspective diagram.As shown in figure 12, when absolute construction 8 is separated from each other, leave the corresponding inclined hole 74 of some and each absolute construction 8 in the head end (far-end) of guiding catheter 7 or head side wall; Such as Figure 12 A, shown in the 12D, inclined hole 74 can be opened in the head end of guiding catheter 7, such as Figure 12 B, shown in Figure 12 C, inclined hole 74 also can be opened on the head side wall of guiding catheter 7, the internal diameter of each inclined hole 74 is greater than the external diameter of absolute construction 8, general 1.4--2.4mm, the angle of inclination of each inclined hole 74 is generally the 16--50 degree, the quantity of inclined hole 74 preferably equals the quantity of absolute construction 8 simultaneously, the coupling part 75 that inclined hole is 74 preferably is taper, coupling part 75 not only can limit controllable bending tune 5 by front release guiding catheter 7 also help to guide absolute construction 8 from inclined hole 74 by front release.If push ablation catheter 1 or rollback guiding catheter 7, such as Figure 12 C, shown in Figure 13, absolute construction 8 will be pushed into blood vessel from the inclined hole 74 interior divergence shapes that outwards are, and the radio-frequency ablation electrode head 9 of absolute construction 8 heads will preferentially contact with blood vessel wall; Push ablation catheter 1 or the distance of rollback guiding catheter 7 and the gradient of inclined hole 74 by control, can control the pressure that distance that absolute construction 8 far-ends are separated from each other and radio-frequency ablation electrode head 9 contact with blood vessel wall.Far-end for absolute construction 8 comes together in the situation that melts paragraph header end 17, and Figure 14 A, Figure 14 B are the vertical section sketch map, and Figure 14 C is perspective view.Shown in Figure 14 A, Figure 14 C, when the far-end of absolute construction 8 comes together in when melting paragraph header end 17, the head end opening of the guiding catheter 7 preferably mode by structural design limits and melts paragraph header end 17 by front release guiding catheter 7, aperture that throat structure 73 makes guiding catheter 7 head end openings preferably can be set less than the external diameter that melts paragraph header end 17 (shown in Figure 14 A), or with the head end opening (shown in Figure 14 B, Figure 14 C) of plug 72 confined bed guiding tubes 7; As shown in figure 14, preferably be provided with the length side channel 76 close and that communicate with blood vessel with absolute construction 8 on the head end sidewall of guiding catheter 7, the length of side channel 76 is generally 12--14mm, this side channel 76 is preferred parallel corresponding with absolute construction 8, the width of side channel 76 is slightly larger than the external diameter of absolute construction 8, be generally 1.4--2.4mm, and the quantity of side channel 76 preferably equals the quantity of absolute construction 8.If push ablation catheter 1 or rollback guiding catheter 7, as shown in Figure 14B, melt paragraph header end 17 because the restriction of plug 72 will so that absolute construction 8 from corresponding side channel 76 protuberance bulgings, will so that radio-frequency ablation electrode head 9 preferentially contact with blood vessel wall; By the distance of control propelling movement ablation catheter 1 or rollback guiding catheter 7, can control the spacing distance of the relative protuberance of absolute construction 8 mid portions and the pressure that radio-frequency ablation electrode head 9 contacts with blood vessel wall.For the middle somewhere of absolute construction 8 situation that far-end is separated from each other again that links together, the design of guiding catheter 7 heads combines Figure 12, Figure 13, design illustrated in Figure 14.Shown in Figure 15 A, in the head side wall of guiding catheter 7 some little inclined holes 74 or some little inclined holes 74 (similar Figure 12 A is set at the head end of guiding catheter 7 of communicating with blood vessel are set, shown in Figure 12 D), then on the sidewall of the guiding catheter 7 of certain distance after the inclined hole 74, arrange and inclined hole 74 side channels 76 corresponding and that parallel with absolute construction 8 again, inclined hole 74 is generally 2.5--5.5mm with the spacing distance of side channel 76, the internal diameter of each inclined hole is slightly larger than the external diameter of absolute construction 8, be generally 1.4--2.4mm, the angle of inclination of each inclined hole 74 is generally the 16--50 degree, coupling part 75 between inclined hole preferably is taper, coupling part 75 not only can limit junction point 18 and controllable bending tune 5 by front release guiding catheter 7 also help to guide absolute construction 8 from inclined hole 74 by front release, the width of side channel 76 preferably is slightly larger than the external diameter of absolute construction 8, be generally 1.4--2.4mm, the length of side channel 76 is close to the length of the part of junction point 18 with absolute construction 8 near-ends, be generally 10--22mm, the quantity of inclined hole 74 and side channel 76 preferably equals the quantity of absolute construction 8.If push ablation catheter 1 or rollback guiding catheter 7, shown in Figure 15 B, absolute construction 8 far-ends will be pushed into blood vessel from the inclined hole 74 interior divergence shapes that outwards are to the part between the junction point 18, the radio-frequency ablation electrode head 9 of absolute construction 8 heads will preferentially contact with blood vessel wall, absolute construction 8 near-ends will be from the side channel 76 protuberance bulgings of correspondence to the part between the junction point 18, swell the most obvious place will preferentially contact with blood vessel wall; The gradient that pushes the distance of ablation catheter 1 or rollback guiding catheter 7 and inclined hole 74 by control can be controlled the pressure that distance that absolute construction 8 far-ends are separated from each other and radio-frequency ablation electrode head 9 contact with blood vessel wall.Be separated from each other and the far-end of the relative absolute construction 8 of part is connected in the situation that melts paragraph header end 17 for the relative absolute construction 8 of part, also can use for reference the thinking of Figure 12, Figure 13, Figure 14, guiding catheter 7 head design schemes illustrated in Figure 15, at the head of guiding catheter 7 inclined hole 74 and side channel 76 are set simultaneously preferably; It is corresponding and preferably be arranged on the sidewall of guiding catheter 7 heads that inclined hole 74 and far-end are connected in the absolute construction 8 that melts paragraph header end 17, but also can be arranged on the opening part of guiding catheter 7 head ends, side channel 76 is corresponding with the absolute construction 8 that is separated from each other and preferably be arranged on the sidewall of the guiding catheter 7 of inclined hole 74 certain distances, side channel 76 and inclined hole 74 are not on same straight line and respectively corresponding with corresponding absolute construction 8, take four absolute construction 8 as example, two inclined holes 74 are on up and down two sidewalls of guiding catheter 7 heads, and two side channels 76 are then on two sidewalls about guiding catheter 7 heads; The size of each inclined hole 74 can allow absolute construction 8 pass through, be generally 1.4--2.4mm, simultaneously the quantity of inclined hole 74 preferably equals the quantity of the absolute construction 8 that is separated from each other, the coupling part 75 that inclined hole is 74 preferably is taper, coupling part 75 not only can limit melt paragraph header end 17 and controllable bending tune 5 by front release guiding catheter 7 also help to guide the absolute construction 8 that is separated from each other from inclined hole 74 by front release, the width of side channel 76 is greater than the maximum transverse diameter of absolute construction 8, be generally 1.4--2.4mm, side channel 76 is close with the length that far-end comes together in the absolute construction 8 that melts paragraph header end 17, be generally 12--14mm, the quantity of side channel 76 preferably equals the quantity that far-end comes together in the absolute construction 8 that melts paragraph header end 17; If push ablation catheter 1 or rollback guiding catheter 7, for the absolute construction 8 that is separated from each other, they will be pushed into blood vessel from the inclined hole 74 interior divergence shapes that outwards are, the radio-frequency ablation electrode head 9 of absolute construction 8 heads will preferentially contact with blood vessel wall, for being connected in the absolute construction 8 that melts paragraph header end 17, since melt paragraph header end 17 by the restriction of the coupling part of 74 of inclined holes will so that these absolute construction 8 from the 76 protuberance bulgings of corresponding side channel, and so that radio-frequency ablation electrode head 9 preferentially contact with blood vessel wall.Inclined hole 74 in the above-mentioned design and side channel 76 also have the effect of in blood vessel injection or injection of contrast medium.In order to make things convenient for absolute construction 8 to form design deformation, can make the easier realization of design deformation by the structural design of adjustment absolute construction 8 or by changing manufactured materials hardness.Figure 12, Figure 13, Figure 14, Figure 15 carry out the design explanation as an example of two absolute construction 8 example, therefore be not limited to the situation of two rule absolute construction 8, only need to adjust quantity and the setting position of inclined hole 74 and side channel 76 according to Figure 12, Figure 13, Figure 14, mentality of designing illustrated in Figure 15 for the situation more than two absolute construction 8.

The situation of fulcrum can not be provided for the deformation of ablation catheter 1 for guiding catheter 7, absolute construction 8 preferably arranges prefabricated deformation, controllable bending tune 5 can arrange prefabricated deformation, then ablation catheter 1 is pressed in the guiding catheter 7, after the head end of guiding catheter 7 arrives assigned address, ablation catheter 1 can be out pushed from the opening of guiding catheter 7 head ends, recovers prefabricated deformation.Shown in Figure 16 A, far-end is come together in two absolute construction 8 that melt paragraph header end 17 be prefabricated into the class subfusiform, this ablation catheter 1 is pressed in the guiding catheter 7, because the restriction of guiding catheter 7, the mid portion that is prefabricated into fusiform two absolute construction 8 will be drawn close mutually.Shown in Figure 16 B, when guiding catheter 7 arrives the opening part of renal artery a on aorta b, the section of melting 6 is pushed out in guiding catheter 7 head end openings, two absolute construction 8 will revert to prefabricated class subfusiform this moment, and the ledge that adheres to radio-frequency ablation electrode head 9 will preferentially contact with blood vessel wall.Shown in Figure 16 C, when controllable bending tune 5 is prefabricated into " C " shape, guiding catheter 7 can be about to the section of melting 6 and push out in guiding catheter 7 head end openings near the opening part of renal artery a on aorta b the time, because the existence of " C " shape bending of controllable bending tune 5, the section of melting 6 also can enter renal artery a from aorta b smoothly.Figure 16 is connected in two absolute construction 8 melting paragraph header end 17 take far-end to carry out the design explanation as example, therefore be not limited to the situation of two absolute construction 8, also be not limited to absolute construction 8 far-ends and be connected in the connected mode that melts paragraph header end 17 these a kind of in twos absolute construction 8, for more than the situation of two absolute construction 8 with other connected mode of absolute construction 8 is applicable too in twos, for example for the absolute construction 8 that is separated from each other, absolute construction 8 need to be prefabricated into head end and near position thereof mutually away from the most obvious state, then be pressed into guiding catheter 7, again for example for the middle somewhere of absolute construction 8 situation that far-end is separated from each other again that links together, absolute construction 8 far-ends need to be become with head end and near position thereof mutually away from the most obvious state to the partial precast between the junction point 18, and absolute construction 8 near-ends are become spindle to the partial precast between the junction point 18, then be pressed into guiding catheter 7, for example be separated from each other for the relative absolute construction 8 of part again and the far-end of the relative absolute construction 8 of part is connected in the situation that melts paragraph header end 17, the absolute construction 8 that is separated from each other need to be prefabricated into head end and near position thereof mutually away from the most obvious state, be prefabricated into spindle and far-end is connected in the absolute construction 8 that melts paragraph header end 17, then be pressed into guiding catheter 7.In addition also can be at the head setting of guiding catheter 7 and absolute construction 8 corresponding inclined holes 74 or/and side channel 76, in will not the situation of the section of melting 6 front release guiding catheters 7, can realize that also absolute construction 8 recovers prefabricated deformation like this.

Figure 17, Figure 18 have shown the mode that changes ablation catheter 1 and the distribution of guiding catheter 7 hardness in the embodiments of the invention by structural design.It is this that to change the hardness of the mode that ablation catheter 1 and guiding catheter 7 hardness distribute and the manufactured materials itself that does not require various piece by structural design different.

Such as Figure 17 A, shown in Figure 17 B, in ablation catheter 1 inside the chicken ribs spline structure shown in Figure 17 A and Figure 17 B is set, be that interval d5 is the structure shown in Figure 17 B apart from a cross section is set, the part that this structure bend represents is had certain elastic Material Filling, preferred high molecular polymer, white space a1 will form a chamber in that ablation catheter 1 is interior, be mainly used in wire, fine duct, the travelings such as optical fiber, certainly white space a1 is not limited to circle, also be not limited to a chamber is only arranged, it is (for example oval according to circumstances can be arranged to other shapes, rectangle etc.), the respectively different member of traveling of more chamber also can be set.Shown in Figure 17 A, Figure 17 B, white space b1 also will form a chamber in ablation catheter 1, but also traveling wire, fine duct, optical fiber etc., white space a1, b1 just can distinguish the different member of traveling like this, certainly white space b1 is not limited to semicircle, also being not limited to only has a chamber, according to circumstances can be arranged to other shapes (such as ellipse, rectangle etc.), and the respectively different member of traveling of more chamber also can be set.Shown in Figure 17 A, owing to the arcuate structure in d3 and the d4 institute inclusion region among shortage Figure 17 B in the included zone of d5, therefore on y direction, the included zone of each d5 will bend easily, and the bending in the zone that all d5 are included will make the structure shown in Figure 17 A form integrally bending.Similarly, shown in Figure 17 C, the white space of b1 sample among two Figure 17 B is set in the included zone of d3, d4, d3 ', d4 ', be white space b1, b2, and this moment white space a1 between white space b1, b2, be in (mainly in the zone that d2 and d2 ' surround) in the included zone of d1, structure among Figure 17 A in the included zone of d6 will be substituted by the structure shown in Figure 17 C, and the structure in the included zone of d5 will be the extension of the structure in the included zone of d1 among Figure 17 C among Figure 17 A; White space a1 will form a chamber in that ablation catheter 1 is interior, be used for the travelings such as wire, fine duct, optical fiber, and white space a1 is not limited to ellipse certainly, and also being not limited to only has a chamber; White space b1 and b2 also will form two chambers in ablation catheter 1, but also traveling wire, fine duct, optical fiber etc., white space b1 and b2 are not limited to semicircle certainly, and also being not limited to only has respectively a chamber; Owing in the included zone of d5, lack the arcuate structure in d3, d4, the included zone of d3 ', d4 ' among Figure 17 C, therefore on y direction, the included zone of each d5 will bend easily, the bending in the zone that all d5 are included will make structure shown in Figure 17 A form integrally bending, this moment is because the d5 both sides all lack supporting construction, therefore compound bending can occur, and pass through to adjust the large young pathbreaker of white space b1 and b2 so that different to the complexity of both direction bending; Certainly, also can the b1 sample white space that three Figure 17 B illustrate be set at three different directions similarly, with the bending of at least three directions of realization, and this project organization can also be by that analogy.Shown in Figure 17 D, Figure 17 E, when the cross section of ablation catheter 1 some part is not circle, the chicken ribs spline structure can be realized in these ablation catheter 1 parts equally, Figure 17 D, Figure 17 E have illustrated the implementation of chicken ribs spline structure in other shapes except circle as an example of semicircular structure example, according to the difference of bending direction, the position that white space a1 and b1 arrange is different.For example, shown in Figure 17 D, white space b1 is arranged in the left side of white space a1, structure among Figure 17 A in the included zone of d6 will be substituted by the structure shown in Figure 17 D, and the structure in the included zone of d5 will be the extension of the structure in the included zone of d1 among Figure 17 D among Figure 17 A, and whole like this stereochemical structure will be easily to white space b1 lateral bend; Shown in Figure 17 E, b1 is arranged in the right of a1, structure among Figure 17 A in the included zone of d6 will be substituted by the structure shown in Figure 17 E, and the structure in the included zone of d5 will be the extension of the structure in the included zone of d1 among Figure 17 E, and whole like this stereochemical structure will be easily to white space b1 lateral bend.In structure shown in Figure 17, by changing white space a1, the size of b1, b2, quantity, and by changing the size of d1, d2, d3, d4, d5, d6, can realize the difference of each section hardness, for example a certain section in Figure 17 A widened d1, dwindling d3 or d4 will be so that this section be not easy deformation, more for example a certain section widen d5 will so that, the easier deformation of this section; Can realize that by the relative position that changes the interior white space a1 of different sections and b1 zone different sections are non-crooked in the same way, for example with the Lower Half horizontal rotary turnback of Figure 17 structure that A illustrates, with so that the arrow side of Lower Half white space b1 in Figure 17 A, the structure after improving like this will help to realize that serpentine is crooked.In a word, the essence of chicken ribs spline structure is by optionally reducing or/and increase the internal structure of some conduit segment and then optionally reduce or/and improve the counter-bending ability of a certain side of the little intrasegmental part of some conduit or a few sides, so that conduit is easier to be crooked or/and form some bending shape to some direction.

Figure 18 has shown that another kind of the distribution by change structure design and then change hardness makes the design of crooked easier realization in the embodiments of the invention.This project organization is the implementation of chicken ribs spline structure in hollow tubular structure, and this kind structure optimization is used for hollow pipe spline structure (such as guiding catheter 7 etc.).This structure mainly by change metal gauze in ablation catheter 1 and guiding catheter 7 tube walls in different conduit segments arrange or ablation catheter 1 and the thickness of guiding catheter 7 tube walls in different conduit segments realizes by changing, certainly metal gauze described here is construed as the project organization of reinforcing duct wall hardness, such as also can being macromolecular material net etc., therefore the essence of this kind design is by optionally reducing or/and increase the structure of some conduit segment tube wall and then optionally reduce or/and improve a certain side of some conduit segment tube wall or the counter-bending ability of a few sides, so that conduit is easier to be crooked or form some bending shape to some direction.Figure 18 changes metal gauze in ablation catheter 1 or guiding catheter 7 tube walls arranging in different conduit segments to describe for example.Shown in Figure 18 A, netting twine represents metal gauze among the figure, can see from the lower-left figure of Figure 18 A, metal gauze in the duct wall is to cover duct wall fully, can see from the picture left above of Figure 18 A, does not have metal gauze in the side pipe wall of conduit, two little spacer segments of conduit are stacked together, structure shown in the right figure of pie graph 18A, owing to do not have metal gauze in the side pipe wall of a bit of conduit of top, so the easier curving to there not being metal gauze of conduit.Certainly also be not limited to the design that does not have metal gauze in the side pipe wall of conduit, shown in Figure 18 D, between two conduit segments that complete metal gauze arranged, four serpentine tinsel f1 are arranged, f2, f3, f4, can be at f1, between f2 and f3, metal gauze is set between f4, and at f2, between f3 and f1, metal gauze is not set between f4, so easier two lateral bends to there not being metal gauze of conduit, the metal gauze of half in like manner also can only be set between every adjacent two serpentine tinsels, the easier four direction to there not being metal gauze of conduit is crooked like this, can also only have four serpentine tinsels and not have metal gauze, whole like this conduit will be crooked to a plurality of directions easily.Also be not limited in addition a certain side of some conduit segment tube wall or the situation that a few side does not have metal gauze, the modes such as the aperture that this can be by changing metal gauze, density, width wiry realize that a certain side of some conduit segment tube wall or a few side are soft or hard than other catheter walls; According to circumstances serpentine quantity wiry can be adjusted, and simultaneously the serpentine tinsel also can be other forms, such as " Z " shape etc.The structure of Figure 18 A can be arranged according to the side sight figure shown in Figure 18 B, and the bending direction of whole like this run will be consistent; The structure of Figure 18 A can be arranged according to the side sight figure shown in Figure 18 C, the bending direction of whole like this run top and the bottom is inconsistent, just can realize complicated bends by a guide wire 70 in this way, for example pass easier realization serpentine guide wire 70 d3 and the crossing zone of d3 ' from Figure 18 C crooked.Shown in Figure 18 B and Figure 18 C, can also change the complexity of each section of conduit bending by the width of adjusting d1, d3, d3 ', d4, d5.Total also is not limited to the situation that conduit cross section is circle in addition, conduit cross section still can design according to this thinking when being the shape such as semicircle, square, but need to consider that these shapes are on the impact of guide wire 70 and the hardness of chicken ribs spline structure own this moment.

The mode of passing through structural design change ablation catheter 1 and guiding catheter 7 hardness that Figure 17, Figure 18 are shown, can also realize by the hardness that changes manufactured materials, for example the cross section of each segment of conduit can all be designs of Figure 18 B, but the included regional manufactured materials of d3, d4 is hard than other segments on the cross section of some segment, and these segments will be not easy to bend so.

Figure 19 is connected in take two absolute construction 8 far-ends to melt paragraph header end 17 as example, and how having shown in the embodiments of the invention distributes by the hardness of adjusting absolute construction 8 makes the easier realization of deformation of design.Shown in Figure 19 A, article two, absolute construction 8a, 8b bending shape are symmetrical each other, relatively swell for semi-cylindrical two absolute construction 8a, 8b are outside for convenient, Figure 17 can be adopted or/and chicken ribs spline structure illustrated in Figure 18, when adopting chicken ribs spline structure illustrated in Figure 17, absolute construction 8 can adopt the design shown in Figure 17 D, and wherein the form of the cross section shown in the dotted line cc is preferably shown in Figure 17 D; When adopting chicken ribs spline structure illustrated in Figure 18, the blank parts in the absolute construction 8 is interpreted as the structural rigidity that absolute construction 8 tube walls keep at a certain distance away and reduces, such as by removing metal gauze, changing the density of metal gauze etc.Shown in Figure 19 B, Figure 19 C, Figure 19 D, the bending shape of two absolute construction 8 also can be asymmetric, and this is very necessary for absolute construction 8 during more than two, and it helps so that ablation points is on the different renal artery cross sections; Similar with the chicken ribs spline structure that Figure 19 A illustrates, the design that Figure 19 B, Figure 19 C, Figure 19 D illustrate also can adopt Figure 17 or/and chicken ribs spline structure illustrated in Figure 18, in order to realize different bending shapes, can realize by the arrangement of adjusting chicken ribs spline structure on each absolute construction 8 difference of each section hardness, the local hardness larger in curvature is preferably less, and easier realization is crooked.The blank parts of absolute construction 8a, 8b represents the less part of hardness on each absolute construction 8 among Figure 19, therefore the hardness that can change the chicken ribs spline structure such as the size by adjusting absolute construction 8a, the upper blank parts of 8b, form, branch's density distributes, and then the change bending shape.Shown in Figure 19 B, radio-frequency ablation electrode head 9 radio-frequency ablation electrode head 9 to the part of absolute construction 8a tail end and the absolute construction 8b is larger to the part curvature that melts paragraph header end 17 in absolute construction 8a, so blank parts is also larger and closeer.Similarly, among Figure 19 C, in order to realize that latter two radio-frequency ablation electrode head 9 of absolute construction 8 deformation equates to the distance of the section of melting 6 major axis centrages, in the situation of two absolute construction 8 equal in length, it is flexible and far-end and mid portion easily bend that absolute construction 8b has been designed to near-end, therefore far-end and the mid portion blank parts of absolute construction 8b are also more intensive, make it more flexible.Among Figure 19 D, latter two radio-frequency ablation electrode head 9 of absolute construction 8 deformation is unequal to the distance of the section of melting 6 major axis centrages, in the situation of two absolute construction 8 equal in length, the length of the most obvious part of median rise of absolute construction 8 on two absolute construction 8 is different, the most obvious part of median rise of absolute construction 8b is longer, this just requires other part curvature of absolute construction 8b larger, more flexible, so the blank parts of the far-end of absolute construction 8b and near-end is also larger, more intensive.As shown in figure 19, the shape of blank parts also can be changeable, can be the shape shown in Figure 19 A, Figure 19 C, Figure 19 D, also can be the shape shown in Figure 19 B, and the technical staff can also be according to concrete other shapes of actual design certainly.Figure 19 carries out the design explanation as an example of two absolute construction 8 example, therefore be not limited to the situation of two absolute construction 8, and is applicable too for the situation more than two absolute construction 8.The blank parts on the absolute construction 8 is interpreted as the structural rigidity reduction that absolute construction 8 keeps at a certain distance away among Figure 19 in addition, and this hardness descends and not only can realize by the mode of change structure design also can realizing by the mode that changes material hardness.Need absolute construction 8 to form the situation of other bending shapes for the technical staff, can the blank parts of absolute construction among Figure 19 8 be adjusted accordingly.

Figure 21 is take two absolute construction 8 as example, and how having shown when absolute construction 8 is separated from each other in the embodiments of the invention distributes by the hardness of adjusting absolute construction 8 makes the easier realization of deformation of design.The meaning that blank parts among Figure 21 on the absolute construction 8 represents is interpreted as the structural rigidity reduction that absolute construction 8 keeps at a certain distance away, this lower hardness not only can realize by the mode of change structure design also can realizing by the mode that changes material hardness, and the hardness distribution of the changes absolute construction 8 such as size that therefore can be by adjusting blank parts, form, distribution density makes it more flexiblely become needed form.Similar to the structural design thinking that absolute construction 8 illustrated in Figure 19 is connected in when melting paragraph header end 17, design illustrated in Figure 21 preferably adopts the chicken ribs spline structure, adopts shown in Figure 17 or/and chicken ribs sample design shown in Figure 180 all can.As shown in figure 21, in the part near absolute construction 8 head ends, blank parts preferably is arranged on absolute construction 8 by the part of the section of melting 6 centrages, and at mid portion and the afterbody of absolute construction 8, blank parts preferably is arranged on absolute construction 8 away from the part of the section of melting 6 centrages; Blank parts all can certainly be arranged on absolute construction 8 by the part of the section of melting 6 centrages or absolute construction 8 part away from the section of melting 6 centrages.Figure 21 B, Figure 21 C are that how explanation realizes that ablation points is on different renal artery cross sections as an example of two absolute construction 8 example.Shown in Figure 21 B, two absolute construction 8a, 8b are uneven in length, and radio-frequency ablation electrode head 9 all is arranged on the head of every absolute construction 8 owing to the length difference of two absolute construction 8, therefore can realize that ablation points is on different renal artery cross sections.Shown in Figure 21 C, article two, the length of absolute construction 8a, 8b also can equate and internal structure is mirror symmetry substantially, just the attachment position of radio-frequency ablation electrode head 9 is different, the far-end of the more close absolute construction 8 of radio-frequency ablation electrode head 9a on the absolute construction 8a can realize also that in this way ablation points is on different renal artery cross sections.Figure 21 carries out the design explanation as an example of two absolute construction 8 example, therefore be not limited to the situation of two absolute construction 8, and is applicable too for the situation more than two absolute construction 8.Need absolute construction 8 to form the situation of other bending shapes for the technical staff in addition, can the blank parts of absolute construction among Figure 21 8 be adjusted accordingly.

Figure 22, Figure 23 are take two absolute construction 8 as example, and how the middle somewhere that has shown absolute construction 8 far-end that links together distributes by the hardness of adjusting absolute construction 8 when being separated from each other again and make the easier realization of deformation of design.The meaning that blank parts among Figure 23 on the absolute construction 8 represents is interpreted as the structural rigidity reduction that absolute construction 8 keeps at a certain distance away, this lower hardness not only can realize by the mode of change structure design also can realizing by the mode that changes material hardness, and the hardness distribution of the changes absolute construction 8 such as size that therefore can be by adjusting blank parts, form, distribution density makes it more flexiblely become needed form.As shown in figure 22, when absolute construction 8 is two, the junction point 18 of two absolute construction 8 can be made the connection joint, connecting the joint can link together semi-cylindrical absolute construction 8a, 8b by breechblock e, and can relatively rotate; When pushing connection joint contact that ablation catheter 1 or rollback guiding catheter 7 make junction point 18 places to the coupling part 75 of 74 of guiding catheter 7 head inclined holes, article two, the far-end of absolute construction 8 will be mutually away from, the radio-frequency ablation electrode head 9 that is attached to absolute construction 8 heads will contact with blood vessel wall; In order to make radio-frequency ablation electrode head 9 and blood vessel wall contact area larger, as shown in figure 22, the semi-cylindrical direction of the head of two absolute construction 8 is horizontal half round post, and other parts of absolute construction 8 are for half-cylindrical longitudinally; In order to make the easier formation of bending shape shown in Figure 22, equally also can adopt the chicken ribs spline structure, outer absolute construction 8b is because curved openings is downward, the downside that therefore can keep at a certain distance away at absolute construction 8b arranges the part that hardness weakens, similarly, inner absolute construction 8b is because curved openings makes progress, and the upside that therefore can keep at a certain distance away at absolute construction 8a arranges the part that hardness weakens; If adopt chicken ribs spline structure illustrated in Figure 17, the cross section enlarged drawing of dotted line cc1, cc2 cross section is the semicircle little figure of upper and lower two width of cloth among Figure 22 among Figure 22, and then the horizontal figure in cross section of the included zone of d6 absolute construction 8a, 8b in Figure 22 namely is respectively the semicircle little figure of upper and lower two width of cloth among Figure 22 among Figure 17 A.Similar to the structural design thinking that absolute construction 8 illustrated in Figure 19 is connected in when melting paragraph header end 17, design illustrated in Figure 23 also preferably adopts the chicken ribs spline structure, adopts shown in Figure 17 or/and chicken ribs sample design shown in Figure 180 all can.As shown in figure 23, in the part near absolute construction 8 head ends, blank parts preferably is arranged on absolute construction 8 by the part of the section of melting 6 centrages, arrive the part of junction point 18 thereafter, blank parts preferably is arranged on absolute construction 8 away from the part of the section of melting 6 centrages, in the part of junction point 18 to absolute construction 8 ends, blank parts preferably is arranged on absolute construction 8 by the part of the section of melting 6 centrages; Blank parts all can certainly be arranged on absolute construction 8 by the part of the section of melting 6 centrages or absolute construction 8 part away from the section of melting 6 centrages, and the technical staff can adjust to the setting position of blank parts according to circumstances.Figure 23 B, Figure 23 C are that how explanation realizes that ablation points is on different renal artery cross sections as an example of two absolute construction 8 example.Shown in Figure 23 B, article two, absolute construction 8a, 8b's is uneven in length, but junction point 18 equates to the partial-length of absolute construction 8 tail ends, radio-frequency ablation electrode head 9 all is arranged on the head of every absolute construction 8 owing to the length difference of two absolute construction 8, therefore can realize that also ablation points is on different renal artery cross sections.Shown in Figure 23 C, article two, the length of absolute construction 8a, 8b also can equate and internal structure is mirror symmetry substantially, just the attachment position of radio-frequency ablation electrode head 9 is different, the far-end of the more close absolute construction 8 of radio-frequency ablation electrode head 9a on the absolute construction 8a can realize that in this way ablation points is on different renal artery cross sections.Figure 23 carries out the design explanation as an example of two absolute construction 8 example, therefore be not limited to the situation of two absolute construction 8, and is applicable too for the situation more than two absolute construction 8.Need absolute construction 8 to form the situation of other bending shapes for the technical staff in addition, can the blank parts of absolute construction among Figure 23 8 be adjusted accordingly.

Be connected in for part absolute construction 8 far-ends and melt paragraph header end 17 and situation that part absolute construction 8 is separated from each other, the design of Figure 19, absolute construction 8 illustrated in Figure 21 can be merged, be that far-end is connected in the absolute construction 8 employings design illustrated in Figure 19 that melts paragraph header end 17, and the absolute construction 8 that is separated from each other adopt design illustrated in Figure 21.

Figure 20 has shown embodiments of the invention are how to make the easier realization of design deformation by the hardness distribution of adjusting controllable bending tune 5, and wherein Figure 20 B, Figure 20 C are the side view after controllable bending tune 5 amplifies.Blank parts among Figure 20 on the controllable bending tune 5 is interpreted as the structural rigidity reduction that controllable bending tune 5 keeps at a certain distance away, this hardness descends and not only can realize by the mode of change structure design also can realizing by the mode that changes material hardness, and the hardness distribution of the changes controllable bending tunes 5 such as size that therefore can be by adjusting blank parts on the controllable bending tune 5, form, branch's density makes it more flexiblely become needed form.Similar with the design of absolute construction 8 illustrated in Figure 19, controllable bending tune 5 also preferably adopts the chicken ribs spline structure; When adopting chicken ribs spline structure shown in Figure 17, controllable bending tune 5 can adopt the design shown in Figure 17 A and Figure 17 B, and wherein the section morphology of the cross section shown in the dotted line cc1 is preferably shown in Figure 17 B among Figure 20 B; When adopting chicken ribs spline structure shown in Figure 180, the blank parts of controllable bending tune 5 is interpreted as the structural rigidity that controllable bending tune 5 tube walls keep at a certain distance away and descends among Figure 20 A, Figure 20 B, Figure 20 C, such as by removing metal gauze, changing the density of metal gauze etc.; If need crooked direction and the opposite direction (being direction shown in the arrow ao2) shown in Figure 20 B arrow ao1, then can adopt the design shown in Figure 20 C.If need controllable bending tune 5 to both sides all than being easier to bending, can adopt the design shown in Figure 20 D, namely preferably respectively Figure 17 is set or/and chicken ribs spline structure illustrated in Figure 18 in controllable bending tune 5 relative both sides; When adopting chicken ribs spline structure illustrated in Figure 17, shown in the similar Figure 17 C of its design, just the size in each zone slightly has adjustment (shown in Figure 20 D middle graph), because the integral hardness of bendable control tune 5 both sides is smaller, controllable bending tune 5 is easier of two lateral bends; When adopting chicken ribs spline structure illustrated in Figure 18, the blank parts of controllable bending tune 5 is interpreted as the structural rigidity that controllable bending tune 5 tube walls keep at a certain distance away and descends among Figure 20 D, such as by removing metal gauze, changing the density of metal gauze etc.Shown in two width of cloth side views about Figure 20 D, the not necessarily full symmetric of arranging of both sides chicken ribs spline structure can have certain dislocation.Realize multi-direction bending (more than or equal to 3 directions) for needs, can adopt the expansion design of chicken ribs spline structure illustrated in Figure 17 and the realization that the chicken ribs spline structure shown in Figure 18 D is helped multi-direction bending by empty bending section 5.Need bendable control tune 5 to form the situation of other bending shapes for the technical staff in addition, can the blank parts of controllable bending tune 5 among Figure 20 be adjusted accordingly.

In addition, Figure 19, Figure 20, Figure 21, Figure 22, blank parts illustrated in Figure 23 can also cushion the pressure of 1 pair of blood vessel of ablation catheter except helping ablation catheter 1 to form the effect of design deformation, play the effect of protection blood vessel.

Figure 24 has shown the main structure of guiding catheter 7 afterbodys in the embodiments of the invention.Shown in Figure 24 A, according to actual needs, the end of guiding catheter 7 (tail end, near-end) can be provided with perforate 77, after being connected with one section conduit 20, perforate 77 links to each other with syringe or priming device, therefore can be by injection in the perforate 77 promoting the circulation of blood pipes or injection Intravascular contrast agents, conduit 20 did not seal when perforate 77 was not used.As shown in figure 24, the afterbody of guiding catheter 7 preferably has Seal Design, for example sealing ring or sealing shroud 79, anti-Hemostatic Oral Liquid spills and prevents to spill to the medicine of intravascular injection or the contrast agent of injection through guiding catheter 7 through guiding catheter 7, what wherein Figure 24 A, Figure 24 B showed is the situation of not inserting ablation catheter 1, what Figure 24 C showed is the situation of inserting ablation catheter 1, and Figure 24 B, Figure 24 C are the enlarged drawing of guiding catheter 7 afterbodys; As shown in figure 24, rigidized cover 78 is preferably arranged around the afterbody of guiding catheter 7 in addition, make guiding catheter 7 afterbodys be difficult for deformation, convenient operation also conveniently simultaneously is connected with other structures or is attached on other structures.Deformation itself also occurs under the control structure control in guiding catheter 7 online, also prefabricated deformation can be set simultaneously.Shown in Figure 24 A, for guiding catheter 7 situation of prefabricated deformation is only arranged, guiding catheter control handle 27 preferably is not set, its end can only arrange jointing 71, and jointing 71 can be connected with syringe, priming device, ablation catheter 1 etc.Figure 25 has shown the main structure of guiding catheter 7 line traffic control structural designs in the embodiments of the invention and how has distributed by the hardness of adjusting guiding catheter 7 and promotes guiding catheter 7 to form required deformation form.In the line traffic control structure of guiding catheter 7 is established, preferably in the mode that increases guide wire 70 tension force (being tractive guide wire 70 or front guiding catheter 7 other parts except guide wire 70 of sending) guiding catheter 7 is controlled, the technical staff also can according to circumstances control guiding catheter 7 in the mode that increases guide wire 70 stress (namely pushing guide wire 70 or rollback guiding catheter 7 other parts except guide wire 70) certainly.Shown in Figure 25 A, in a side pipe wall of guiding catheter 7, be provided with guide wire 70, when increasing the tension force of guide wire 70, guiding catheter 7 will bend to the side that guide wire 70 is set, also i.e. direction shown in the arrow ao1 among the figure can arrange respectively guide wire 70 if guiding catheter 7 needs to realize multidirectional control bending on several directions of guiding catheter 7.In order to make things convenient for guiding catheter 7 to form the deformation form that needs, the hardness that can change guiding catheter 7 segments distributes, and the change that this hardness distributes not only can realize by the mode of change structure design also can realizing by the mode that changes material hardness; Figure 25 B, Figure 25 C be the structural design that changes guiding catheter 7 segments be that example describes, the blank parts of guiding catheter 7 tube walls represents the part that structural pipe wall hardness lowers among Figure 25 B, Figure 25 C, for the mode of the material hardness that passes through change guiding catheter 7 segments, only the blank parts of guiding catheter 7 tube walls among Figure 25 B, Figure 25 C need to be made with softer material.Shown in Figure 25 B, Figure 25 C, guiding catheter 7 can adopt the chicken ribs spline structure, and preferably adopts the design of chicken ribs spline structure shown in Figure 32; Shown in Figure 25 B, when needs are strengthened guiding catheter 7 to the bending of direction shown in the arrow ao1, the project organization of strengthening tube wall hardness in guiding catheter 7 tube walls of arrow ao1 side can be weakened, for example can keep at a certain distance away the tinsel in arrow ao1 side guiding catheter 7 tube walls is removed, when increasing the tension force of guide wire 70, guiding catheter 7 will be easier to be crooked to arrow ao1 direction; Shown in Figure 25 C, for the situation of line traffic control compound bending, the project organization of strengthening tube wall hardness in the guiding catheter 7 both sides tube walls can be weakened, for example, can keep at a certain distance away the tinsel in arrow ao2 and arrow ao3 side guiding catheter 7 tube walls is removed; Can be with reference to the design of figure 32D for the crooked chicken ribs spline structure of multidirectional control.In addition, guiding catheter 7 heads also can be made first the bending shape to certain direction, like this when guiding catheter 7 does not have line traffic control structure control deformation, also can help guiding catheter 7 to arrive renal artery, if when guiding catheter 7 has its deformation of line traffic control structure control, the prefabricated case of bending of guiding catheter 7 can also increase the control bending direction of guiding catheter 7, for example the bending direction of the line traffic control structure control deformation of guiding catheter 7 is arranged to so just can control the bending of both direction with to preset the deformation bending direction opposite.Decide according to the deformation form of guiding catheter 7 in the traveling path of guide wire 70 in guiding catheter 7 tube walls, general parallel with the guiding catheter 7 major axis neutral conductors; Guide wire 70 can be connected to guiding catheter 7 tail ends independently on the guiding catheter control handle 27, this guiding catheter control handle 27 can be connected with joystick 2 or independent the existence, guide wire 70 in the guiding catheter 7 also can be directly connected to joystick 2, by joystick 2 controls (aftermentioned).Magnetron configuration design for guiding catheter 7, preferably permanent magnet, electric magnet or other can be arranged in the tube wall of guiding catheter 7 heads and near position thereof by the material of attraction, can control the bending of more than 7 direction of guiding catheter by the change of externally-applied magnetic field direction.The guiding catheter 7 of structural design and the hardness of the manufactured materials of guiding catheter 7 segments and then the hardness that changes guiding catheter 7 also can be by adjusting to(for) the guiding catheter 7 that adopts the magnetron configuration design distribute and make the easier realization of deformation of design.Certainly the technical staff can be according to actual needs, adjusts permanent magnet, electric magnet or other can by the setting position of the material of attraction on guiding catheter 7, make guiding catheter 7 form the deformation of other shapes.

Described ablation catheter 1 and guiding catheter 7 outer surfaces can labelling development scales, with the degree of depth of indication ablation catheter 1 and guiding catheter 7 intravasations and the convenient length of indirectly measuring organization of human body under the image documentation equipments such as ultrasonic, X ray, width etc.Different developing marks also can be set on ablation catheter 1 and the guiding catheter 7 to be used for distinguishing different conduits under the image documentation equipments such as ultrasonic, X ray.Different developing marks preferably is set on each absolute construction 8 to be used for distinguishing different absolute construction 8 under the image documentation equipments such as ultrasonic, X ray, for example at an absolute construction 8 subscript trianglees, and another absolute construction 8 mark squares, or at an absolute construction 8 subscripts three bands, and another absolute construction 8 marks two bands.Developing mark also can be set on ablation catheter 1 and the guiding catheter 7 in addition to be used for distinguishing different axial-rotation states under the image documentation equipments such as ultrasonic, X ray, such as the left surface at ablation catheter 1 short-term that can develop is set under the image documentation equipments such as ultrasonic, X ray, at the right flank of ablation catheter 1 short-term that another can develop is set under the image documentation equipments such as ultrasonic, X ray, two short-terms overlap when ablation catheter 1 is horizontal, when ablation catheter 1 axial-rotation certain angle, short-term then is separated by a distance.In order to reduce the probability of ablation catheter 1 and 7 pairs of blood vessel injuries of guiding catheter, preferably, ablation catheter 1 is preferably as far as possible smooth with the place that guiding catheter 7 contacts with blood vessel wall, and it is round and smooth that the while form is preferably tried one's best, and the head of ablation catheter 1 and guiding catheter 7 is preferably softer in addition.

The part that may directly or indirectly contact with human body fluid or tissue in ablation catheter 1 and the guiding catheter 7 all must reach accordingly and the national standard of human body fluid or tissue contacting material, for can not reaching ablation catheter 1 that above-mentioned requirements may directly or indirectly contact with human body fluid or tissue again and the part of guiding catheter 7, must wrap up with the material of the national standard that meets the material that contacts with human body fluid or tissue outside it.Ablation catheter 1 and guiding catheter 7 may should be able to tolerate with the manufactured materials of the direct or indirect contact portion of human body at least a medical disinfecting method.Ablation catheter 1 may should insulate with the part that human body directly or indirectly contacts with guiding catheter 7, can the outer wrapping insulant for the place that can not reach insulating requirements.

During the acting on catheter body section 4 controllable bending tune 5 is not set of above-mentioned controllable bending tune 5, can by catheter body section 4 on behalf of enforcement, only the design of above-mentioned controllable bending tune 5 need to be applied to catheter body section 4 and get final product.

The technical staff can according to actual requirement to the design of above-mentioned these ablation catheters 1 and guiding catheter 7 merge, improvement and cross-reference, these equivalences change and modify and fall into equally embodiments of the invention claim limited range.

Be connected in joystick 2 by the situation of joystick 2 responsible controls for guiding catheter 7, joystick 2 can be controlled guiding catheter 7 and ablation catheter 1 simultaneously.Can controlled bending direction quantity and can controlled bend mode according to guiding catheter 7, the design of joystick 2 is slightly different.Because the general line traffic control structure that adopts is controlled the deformation of guiding catheter 7, therefore the design of joystick 2 is take the line traffic control structure as the basis, for other control modes of guiding catheter 7 deformation, only need to improve a little on the basis of online control structure joystick 2.Figure 26, Figure 27, Figure 28 all are take the line traffic control structure as example, have shown the main structure of joystick 2.In Figure 26 A, Figure 26 C, the design illustrated in Figure 27, guiding catheter 7 and 2 stable linking to each other of joystick are by joystick 2 responsible controls; In the design that Figure 26 B illustrates, guiding catheter 7 is connected with ablation catheter 1 afterbody by terminal jointing 71, and when needing, guiding catheter 7 can separate with ablation catheter 1 end again; In the design illustrated in Figure 28, guiding catheter 7 links to each other with guiding catheter control handle 27, is responsible for control by guiding catheter control handle 27.Dotted line ac represents wire, fine duct, the optical fiber in the joystick 2 among Figure 26, Figure 27, Figure 28.

Figure 26 has shown can not be by in the situation of line traffic control structure control guiding catheter 7 bending directions in the embodiments of the invention, the main structure of joystick 2.Figure 26 A, Figure 26 C have shown in guiding catheter 7 and the joystick 2 stable situations that link to each other, the main structure of joystick 2, Figure 26 B has shown that guiding catheter 7 is by in terminal jointing 71 and the situation that ablation catheter 1 afterbody is connected, the main structure of joystick 2, wherein Figure 26 C is the schematic cross-section that dotted line cc cross section amplifies among Figure 26 A.Shown in Figure 26 A, joystick 2 is preferably designed to shape shown, mainly formed by lever 271 and lever 226, wherein lever 271 generally is positioned at the front portion of joystick 2, the main control guiding catheter 7 of being responsible for, and lever 226 generally is positioned at the rear portion of joystick 2, the main control ablation catheter 1 of being responsible for; Lever 271 and 7 terminal linking to each other of guiding catheter, lever 271 is connected the groove tooth slide construction that indicates by dotted rectangle ar among the figure and is connected with lever, groove tooth slide construction is comprised of the annular hook formation 272 of lever 271 afterbodys and annular hook formation 240 mutual the coincideing of lever 226 heads, and can relatively rotate after connecting.Shown in Figure 26 A, Figure 26 C, ablation catheter 1 links to each other with the connecting rod 251 that the cross section radial launches, connecting rod 251 links to each other with annular control knob 250, push (showing such as Figure 26 B) or rollback annular control knob 250 and can realize advancing of ablation catheter 1 or rollback, because control knob 250 circlewise, even therefore rotary manipulation handle 226 does not still affect by annular control knob 250 control ablation catheters 1.Figure 26 C has shown the schematic cross-section that Figure 26 A dotted line cc cross section amplifies, and helps to further specify the space structure relation of connecting rod 251, annular control knob 250, lever 226.Shown in Figure 26 C, ablation catheter 1 links to each other with the connecting rod 251 that the cross section radial launches, connecting rod 251 passes one section fluting 244 and the annular control knob 250 on the lever 226, because fluting 244 can limit the rotation of connecting rod 251, any one of therefore rotating annular control knob 250 and lever 226 can both realize that both rotate together, and then realizes the rotation of ablation catheter 1; Certainly the length of fluting 244 is the distance that ablation catheter 1 can move, this length is generally less than the width of annular control knob 250, so annular control knob 250 can cover fluting 244, and annular control knob 250 also is unlikely to appear the internal structure of joystick 2 when sliding; The quantity of connecting rod 251 and fluting 244 differs and is decided to be four, can adjust according to actual needs.Shown in Figure 26 A, afterbody at lever 226 preferably is provided with energy exchange joint 201, energy exchange joint 201 (includes wire by cable 23, optical fiber or fine duct etc., Fig. 1 shows) with melt generating means part 3 and link to each other, main be responsible for receiving by melt energy that generating means 3 transmits and with this energy by the wire in the joystick 2, fine duct, optical fiber ac etc. transfers to and melts 9, other need the part of energy supply on the ablation catheter 1, need on the part of energy supply and the joystick 2 to need the part of energy supply on the guiding catheter 7, energy exchange joint 201 is also with transmitting ablation catheter 1 simultaneously, sensor signal on guiding catheter 7 and the joystick 2 and reception are melted instruction that generating means 3 transmits and it are passed to ablation catheter 1, the effect of guiding catheter 7 and joystick 2.Shown in Figure 26 A, the position of the end of lever 226 and energy exchange joint 201 vicinities according to circumstances can arrange liquid perfusion joint 202, liquid perfusion joint 202 links to each other with fine duct in the ablation catheter 1, be used for providing liquid coolant to ablation catheter 1, contrast agent etc., liquid perfusion joint 202 links to each other with liquid filling apparatus 203 by conduit outside joystick 2, this liquid filling apparatus 203 can be arranged on and melt on the generating means part 3, melted the control of generating means part 3, also can be to be independent of the system that melts generating means part 3, this liquid filling apparatus 203 can be manually to carry out the liquid perfusion simultaneously, also can be automatically to carry out the liquid perfusion.The signable ablation catheter of the outer surface of the outer surface of this external lever 226 and annular control knob 250 1 pushes distance and pushes direction, in the signable lever 271 of outer surface and lever 226 relative rotation angle and the direction of rotation of outer surface and the lever 226 of annular hook formation 272.Shown in Figure 26 B, whole joystick 2 mainly is comprised of lever 217, guiding catheter 7 will not link to each other with joystick 2, ablation catheter 1 end will link to each other with the head end of lever 217, near-end at ablation catheter 1 is provided with rigidized cover 48, so that ablation catheter 1 is difficult for deformation, convenient operation with the place that joystick 2 is connected.Shown in Figure 26 B, guiding catheter 7 links to each other with ablation catheter 1 afterbody by terminal jointing 71, the rigidized cover 48 of ablation catheter 1 afterbody helps ablation catheter 1 to link to each other with jointing 71, and sealing ring or sealing shroud 79 in the guiding catheter 7 can prevent that Hemostatic Oral Liquid spills and prevent to spill to the medicine of intravascular injection or the contrast agent of injection through guiding catheter 7 through guiding catheter 7; Control to ablation catheter 1 will be mainly by front sending or rollback operation handle 217 and rotary manipulation handle 217.Shown in Figure 26 B, similarly, preferably be provided with energy exchange joint 201 at the afterbody of lever 217, according to circumstances the next door of energy exchange joint 201 can arrange liquid perfusion joint 202.

Figure 27 has shown the main structure that can pass through the joystick 2 of line traffic control structure control guiding catheter 7 bending directions in the embodiments of the invention; Wherein Figure 27 A, Figure 27 B have shown that joystick 2 can control the main structure of guiding catheter 7 joystick 2 in the crooked situation of direction, Figure 27 C, Figure 27 D have shown that joystick 2 can control the main structure of guiding catheter 7 joystick 2 in the crooked situation of both direction, Figure 27 E, Figure 27 F be situation take four guide wires 70 as example, shown that joystick 2 can control the main structure of guiding catheter 7 joystick 2 in the crooked situation of a plurality of directions (〉=3 direction); Because the design of lever 226 is identical with the design of lever 226 among Figure 26 A, Figure 26 C among Figure 27, therefore Figure 27 has mainly shown the construction features of lever 271, in addition for the place just no longer repetition here identical with the design of joystick 2 illustrated in Figure 26 of the design of joystick illustrated in Figure 27 2.Figure 27 A, Figure 27 B have shown that joystick 2 can control guiding catheter 7 in the crooked situation of direction, and the main structure of joystick 2 preferably arranges a guide wire 70 this moment; Wherein Figure 27 B is the schematic cross-section that dotted line cc1 cross section amplifies among Figure 27 A.Shown in Figure 27 A, after guide wire 70 goes out from guiding catheter 7 terminal travelings, link to each other through the control knob 237 of similar annular on the interface channel 277 on the lever 271 and the encircling operation handle 271, control knob 237 can be in lever 271 slips; When pushing control knob 237 to arrow ao1 direction, guide wire 70 will be subject to tractive, can control in this way the bending direction of guiding catheter 7.Being subject to undue tractive for fear of guide wire 70 causes the bending of guiding catheter 7 to injure blood vessel wall, buffer structure can be set, one section of the centre that is about to the guide wire 70 of traveling interface channel 277 in is with spring or tool fine rule replacement springy, Figure 27 A describes as example so that spring 282 to be set, at interface channel 277 diameters at spring 282 places slightly slightly to hold spring 282, when tractive guide wire 70, spring 282 can stretch, can play like this effect of buffering traction force, simultaneously since the slightly larger in diameter of spring 282 in the diameter of both sides interface channel 277, therefore the extension distance of spring 282 can not surpass the part that interface channel 277 expands, this just so that spring 282 is unlikely to surpass spring 282 maximum extension apart from the lower pulling force that produces to the tension force of the guide wire 70 of guiding catheter 7 head ends, also just is equivalent to set a pulling force limit value.Certainly be subject to undue tractive for fear of guide wire 70 and cause the bending of guiding catheter 7 to injure blood vessel wall, can also connect tension pick-up at guide wire 70.In addition, the technical staff can also regulate and control the sensitivity that control knob 237 is controlled guide wires 70 by initial tension, traveling path, the interface channel 277 of guide wire 70 in joystick 2 of regulating guide wire 70 in the modes such as openings of sizes of lever 271 females according to actual needs.Rotation for the rotation control operation handle 271 by control knob 237 can arrange groove tooth slide construction at control knob 237 and 271 of levers; Shown in Figure 27 B, the little rectangle frame rc of dotted line is the position at groove tooth slide construction place, image in the dotted line large rectangle frame has shown the enlarged drawing of groove tooth slide construction, groove tooth slide construction is comprised of groove 285 and projecting teeth 286, Figure 27 B is arranged at respectively on control knob 237 and the lever 271 as example take groove 285 and projecting teeth 286 and describes, and also groove 285 and projecting teeth 286 can be arranged at respectively on lever 271 and the control knob 237 as the case may be; When Spin Control button 237, because the existence of groove tooth slide construction will drive lever 271 and rotate together, slide and can not be affected again in control knob 237 front and back simultaneously; The technical staff is position and the magnitude setting of adjustment tank tooth slide construction as required, as long as guarantee control knob 237 and lever 271 can rotate together and the front and back of control knob 237 are slided unaffected.Be handled easily, at signable control knob 237 displacements of the outer surface of lever 271 and control knob 237 and moving direction, in the outer surface of lever 226, the outer surface of annular hook formation 272 and the signable lever 271 of outer surface and lever 226 relative rotation angle and the rotation direction of control knob 237.Figure 27 C, Figure 27 D have shown that joystick 2 can control guiding catheter 7 in the crooked situation of both direction, the main structure of joystick 2, and wherein Figure 27 D is the schematic cross-section that dotted line cc2 cross section amplifies among Figure 27 C.Shown in Figure 27 C, two guide wire 70a, 70b preferably are set this moment, two guide wire 70a, 70b control the bending of 7 one directions of guiding catheter with each, and preferably on relative position, link to each other with control knob 237 through interface channel 277a, 277b respectively, the tractive that spring 282 is used for 237 pairs of guide wires 70 of dash-control button similarly also can be set; Control knob 237 can before and after slide, when control knob 237 slides to arrow ao2 direction, guide wire 70b will be subject to tractive, spring 282b stretches, and guide wire 70a is owing to the existence of interface channel 277a far-end funnel-like groove 278a, it is in relaxation state; When control knob 237 slides to arrow ao3 direction, guide wire 70a will be subject to tractive, and spring 282a stretches, and guide wire 70b is because the existence of interface channel 277b far-end funnel-like groove 278b, and it is in relaxation state.Similarly, the technical staff can be according to actual needs regulates and control the sensitivity that control knob 237 is controlled two guide wires 70 by traveling path joystick 2 in of the initial tension of regulating guide wire 70, guide wire 70, the modes such as position, funnel-like groove 278 openings of sizes and setting position that control knob 237 is charged into lever 271 parts, so that control knob 237 leaves in the situation of initial position same distance the tractive that two guide wires 70 are subject to identical or different big or small power in different directions.Similarly, in order to realize the rotation by the rotation control operation handle 271 of control knob 237, what the design shown in Figure 27 C, Figure 27 D can adopt also that Figure 27 B illustrates arranges groove tooth slide construction at control knob 237 and 271 of levers.If guiding catheter 7 has the prefabricated Bending Deformation of a direction, and thereby guide wire 70 is arranged on the another one direction realizes 7 two relative directions of control guiding catheter with the prefabricated Bending Deformation of antagonism bending, need in this case from guide wire 70a, 70b, to remove one, and remove corresponding accessory structure.Similarly, at signable control knob 237 displacements of the outer surface of lever 271 and control knob 237 and moving direction, in the outer surface of lever 226, the outer surface of annular hook formation 272 and the signable lever 271 of outer surface and lever 226 relative rotation angle and the rotation direction of control knob 237.Figure 27 E, Figure 27 F are that situation take four guide wires 70 is as example, shown that joystick 2 can control the main structure of guiding catheter 7 joystick 2 in the crooked situation of a plurality of directions (〉=3 direction), wherein Figure 27 F is the schematic cross-section that dotted line cc3 cross section amplifies among Figure 27 E.Shown in Figure 27 E, the control knob 237 of control guide wire 70 is replaced by console panel 238 among Figure 27 A, Figure 27 B, Figure 27 C, Figure 27 D, console panel 238 is not charged into the part of lever 271, and the contact surface between lever 271 and the console panel 238 is the part in spherical universal joint, therefore console panel 238 can rotate to a plurality of directions, and promotes forward or backward console panel 238 can not move it and skid off lever 271.Because the cause chart 27E in cross section has only shown two guide wire 70a, 70c.Shown in Figure 27 E, Figure 27 F, each four guide wire 70a, 70b, 70c, 70d that controls 5 one direction bendings of controllable bending tune will pass through interface channel 277a, 277b respectively, 277c, 277d link to each other with console panel 238, four guide wires 70 preferably are uniformly distributed on the circumference of console panel 238 and lever 271, similarly also buffer structure can be set, the tractive that spring 282 is used for 238 pairs of guide wires 70 of dash-control dish for example is set; When console panel 238 rotates to direction shown in the arrow ao4, guide wire 70c will be subject to tractive, and spring 282c stretches, and guide wire 70b is because the existence of interface channel 277b far-end funnel-like groove 278b, and it is in relaxation state; When console panel 238 rotates to direction shown in the arrow ao5, guide wire 70a will be subject to tractive, and spring 282a stretches, and guide wire 70c is because the existence of interface channel 277c far-end funnel-like groove 278c, and it is in relaxation state; If console panel 238 rotation directions are not on any guide wire 70, to have two adjacent guide wires 70 to be subject to tractive this moment, guiding catheter 7 will be crooked to the direction that two guide wires 70 that are subject to tractive are made a concerted effort like this, namely realize the multi-direction bending of control guiding catheter 7 by such mode.Similarly, the technical staff can also be according to actual needs regulate and control the sensitivity that console panel 238 is controlled four guide wires 70 by initial tension, the modes such as traveling path, funnel-like groove 278 openings of sizes and setting position of guide wire 70 joystick 2 in of regulating guide wire 70, so that console panel 238 leaves in the situation of initial position same distance the tractive that four guide wires 70 are subject to identical or different big or small power in four guide wire 70 directions.Similarly, in signable console panel 238 rotational angles of the outer surface of lever 271 and console panel 238 and rotation direction, in the outer surface of lever 226, the outer surface of annular hook formation 272 and the signable lever 271 of outer surface and lever 226 relative rotation angle and the rotation direction of console panel 238.Figure 27 E, Figure 27 F only carry out the structure explanation as an example of four guide wires 70 example, the design shown in Figure 27 E, Figure 27 F can also be used for expansion for the situation of guide wire 70 more than or equal to one.

Guiding catheter 7 also can directly link to each other with guiding catheter control handle 27, be responsible for control by guiding catheter control handle 27, preferred guiding catheter control handle 27 can engage with the joystick 2 of control ablation catheter 1 and break this moment, design illustrated in Figure 28 is with Figure 26, design illustrated in Figure 27 is that the basis is carried out improved, improved design is mainly improved lever 226, therefore in the design of guiding catheter control handle 27 illustrated in Figure 28 and joystick 2 with Figure 26, the place that design illustrated in Figure 27 is consistent just repeats no more here.Figure 28 be take guiding catheter control handle 27 can control guiding catheter 7 in the situation of a direction bending guiding catheter control handle 27 and the design of joystick 2 as example, illustrated how the present invention realizes guiding catheter control handle independently 27 and joystick 2 are bonded with each other and break, realized that namely both separable uses also can engage use; Wherein Figure 28 B is the sketch map of guiding catheter control handle 27, and Figure 28 C is the sketch map of joystick 2, and Figure 28 A is the sketch map that both are bonded together, and Figure 28 D, Figure 28 E are respectively the schematic cross-sections that dotted line cc1 among Figure 28 A, cc2 cross section amplify.Shown in Figure 28 B, guiding catheter control handle 27 mainly is comprised of lever 271', lever 273, control knob 237', and the rotation between lever 271' and lever 273 levers can be by being realized by annular hook formation 272 and the annular hook formation 270 mutual groove tooth slide constructions that form that coincide shown in the dotted rectangle ar among the figure.Shown in Figure 28 C, joystick 2 mainly is comprised of lever 241, annular control knob 250, connecting rod 251, energy exchange joint 201, the scheme of mentioning among the implementation of rotating together of lever 241 and annular control knob 250 and Figure 41 is identical, according to circumstances arranges or liquid is not set and pour into joint 202.When guiding catheter control handle 27 needs to engage with joystick 2, ablation catheter 1 will at first be inserted in guiding catheter 7 through guiding catheter control handle 27, shown in Figure 28 A, Figure 28 B, Figure 28 C, guiding catheter control handle 27 and engaging of joystick 2 become a control handle and mainly rely on taken off groove tooth slide construction on lever 273 and the lever 241, but this can take off groove tooth slide construction and is comprised of the pressure hook shape structure 242 on the draw-in groove 293 on the lever 273, cone cylinder groove 292, snap ring 297, hole clipping 299 and the lever 241, the outstanding tenon 243 of cone cylinder.Such as Figure 28 A, shown in Figure 28 B, during joint, but with 242 pairs of draw-in grooves 293 of pressure hook shape structure, to bore the outstanding tenon 243 of cylinder and aim at cone cylinder groove 292, then push operation handle 241 or back pressure guiding catheter control handle 27, because that but the pressure of pressure hook shape structure 242 heads is turned round 294 inclined-plane is relative by the inclined-plane of lever 241 with snap ring 297, but pressure hook shape structure 242 will be taken advantage of a situation and be entered draw-in groove 293, the outstanding tenon 243 of cone cylinder also will enter cone cylinder groove 292, when lever 273 and lever 241 approaching contacting, but pressure hook shape structure 242 will spring in the hole clipping 299 that is comprised of snap ring 297 and lever 273, because but the pressure of pressure hook shape structure 242 heads turns round 294 and the restriction of hole clipping 299, guiding catheter control handle 27 will be very stable with engaging of joystick 2.Such as Figure 28 A, shown in Figure 28 B, during separation, but the pressure of pressing simultaneously two pressure hook shape structure 242 heads on the relative position turns round 294 it is withdrawed from the hole clipping 299, take advantage of a situation simultaneously and push guiding catheter control handle 27 or pullback operation handle 241, because that but the inclined-plane of snap ring 297 and the pressure of pressure hook shape structure 242 heads are turned round 294 inclined-plane is relative, pressure turns round 294 will enter draw-in groove 293 again, along with lever 273 and lever 241 further away from each other, but the head of pressure hook shape structure 242 pressure is turned round 294 and will be ejected draw-in groove 293, bore simultaneously the outstanding tenon 243 of cylinder and also will withdraw from cone cylinder groove 292, ablation catheter 1 withdraws from guiding catheter 7 subsequently, finishes separation.But but in order to make pressure hook shape structure 242 can pass in and out smoothly the rotation that 293 while of draw-in groove draw-in groove 293 can limit again pressure hook shape structure 242, shown in Figure 28 D, but the width of draw-in groove 293 is preferably close with pressure hook shape structure 242, but and can just block pressure hook shape structure 242, and the height of draw-in groove 293 is preferably greater than the thickness of press button 294.In order to realize the together rotation of lever 273 and lever 241, shown in Figure 28 D, Figure 28 E, can between the outstanding tenon 243 of cone cylinder and lever 273, the groove tooth slide construction that dotted rectangle rc illustrates among similar Figure 42 be set in addition; Amplified this structure among Figure 28 E in the dotted line large rectangle, wherein preferably groove 295 is arranged on the lever 273, projecting teeth 296 is arranged on the outstanding tenon 243 of cone cylinder, the technical staff also can be arranged on groove 295 on the outstanding tenon 243 of cone cylinder as required, and projecting teeth 296 is arranged on the lever 273; Four groove tooth slide constructions are arranged among Figure 28 D, Figure 28 E, and the technical staff can adjust its quantity and branch as required.In addition, but pressure hook shape structure 242 preferably is set to two, and the technical staff can adjust as required.Similarly, be handled easily guiding catheter control handle 27, can be on control knob 237', lever 271' indicates displacement and the moving direction of control knob 237', on the control knob 237', on the lever 271', lever 273 indicates lever 271' and lever 273 relative rotation angle and direction of rotation; In order to make things convenient for guiding catheter control handle 27 to engage with joystick 2, can indicate respectively pairs of bit line that both engage, para-position sign etc. on the guiding catheter control handle 27 with on the joystick 2.Only to be the design that can control the guiding catheter control handle 27 of guiding catheter 7 in the situation of a direction bending and joystick 2 take guiding catheter control handle 27 describe as example Figure 28, can two-wayly or multidirectional control crooked situation for guiding catheter 7, only the lever 271' among Figure 28 need to be replaced to guiding catheter 7 can two-way or multidirectional lever 271 or the lever 213 of controlling in the crooked situation.Can take off in addition Fastening tenon structure and mentality of designing also can expand for other designs of joystick 2 and other controller's design schemes.

If be designed in the situation of a joystick 2 in guiding catheter control handle 27 and joystick 2 fusions, need to guide guiding catheter 7 intravasations with seal wire, the preferred not head end opening of confined bed guiding tube 7, inclined hole 74 or side channel 76 by seal wire being passed guiding catheter 7 head end openings and guiding catheter 7 heads are bootable guiding catheter 7 intravasations, the situation that inclined hole 74 or side channel 76 are not set for guiding catheter 7 heads, the inclined hole 74 that similar Figure 26 B illustrates can be set in the head side wall of guiding catheter 7, is bootable guiding catheter 7 intravasations by the inclined hole 74 that seal wire is passed on guiding catheter 7 head end openings and the head side wall.

The appearance curve of joystick 2 and guiding catheter control handle 27 preferably makes things convenient for holding and controlling of staff in the design of above-mentioned these joysticks 2 and guiding catheter control handle 27.The part that may directly or indirectly contact with human body fluid or tissue in joystick 2 and the guiding catheter control handle 27 all must reach accordingly and the national standard of human body fluid or tissue contacting material, for can not reaching joystick 2 that above-mentioned requirements may directly or indirectly contact with human body fluid or tissue again and the part of guiding catheter control handle 27, must wrap up with the material of the national standard that meets the material that contacts with human body fluid or tissue outside it.Joystick 2 and guiding catheter control handle 27 may should be able to tolerate with the manufactured materials of the direct or indirect contact portion of human body at least a medical disinfecting method.Joystick 2 may should insulate with the part that human body directly or indirectly contacts with guiding catheter control handle 27, can the outer wrapping insulant for the place that can not reach insulating requirements.The technical staff can according to actual requirement to the design of above-mentioned these joysticks 2 and guiding catheter control handle 27 merge, improvement and cross-reference, these equivalences change and modify and fall into equally embodiments of the invention claim limited range.

As shown in Figure 1, melting generating means 3 is energy that corresponding form is provided for the part that needs energy supply on ablation catheter 1, guiding catheter 7, joystick 2, the guiding catheter control handle 27, for example when guiding catheter 7 needs intellectual material to change shape, melting generating means 3 can provide and induce intellectual material to change the needed energy of shape.Melt simultaneously generating means 3 and can receive and process the information that ablation catheter 1, guiding catheter 7, joystick 2, guiding catheter control handle 27 transmit, information after the processing can partly or entirely be presented on the display 320 that melts generating means 3, and the information after this processing can also feedback regulation melts the energy output of generating means 3.The control parameter that melts generating means 3 can carry out by the display 320 that melts generating means touch screen control or by parameter button 330 is set regulating; Melt generating means 3 and should be provided with the joint of energy output and the joint 311 of sensor signal input, also should be provided with simultaneously the joint 321 that joins with external power supply, be used for receiving the electric energy that is transmitted by power supply circuits.Need energy supply and be not provided with the equipment of operating switch at joystick 2 or guiding catheter control handle 27 for ablation catheter 1, joystick 2, guiding catheter 7 and guiding catheter control handle 27, preferably be provided with operating switch on the generating means 3 melting.For ablation catheter 1 or/and the situation of coolant, rewarming agent and infusion liquid that guiding catheter 7 needs, melt generating means 3 and carry out automatic or manual to ablation catheter 1 perfusion coolant, rewarming agent and infusion liquid or/and guiding catheter 7 can be provided with filling apparatus, melt generating means 3 this moment should have corresponding pipeline to communicate with the container that coolant, rewarming agent and infusion liquid raw material or finished product are provided.The priming device that connects for the terminal perforate 77 of guiding catheter 7 is arranged on the situation that melts generating means 3, melts generating means 3 these priming devices of reply and controls and arrange corresponding control panel or control knob.Melting generating means 3 can be to merge above-mentioned functions in the complete machine of one, also can be the split air conditioner of exercising respectively difference in functionality, will independently be an extension set for the part of radio-frequency ablation electrode head 9 energy supplies for example, independently is another extension set with filling apparatus.

Claims

1. a kidney goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that comprising:

Ablation catheter (1), guiding catheter (7), joystick (2) and melt generating means (3), wherein ablation catheter (1) comprises catheter body section (4) and the section of melting (6) from lower to upper successively; Wherein

Described catheter body section (4) links to each other with joystick (2);

The described section of melting (6) comprises at least two absolute construction (8), and the near-end of described absolute construction (8) links to each other, and the described section of melting (6) has at least to be equipped with on the absolute construction (8) and melts (9); The described head (9) that melts links to each other with energy exchange joint (201) on the joystick (2) by wire, conduit, microwave antenna or optical fiber, described energy exchange joint (201) by wire, conduit, microwave antenna or optical fiber with melt generating means (3) and link to each other;

Described guiding catheter (7) is by tractive or push an end and be attached on guiding catheter (7) head end, and the other end is crooked by guide wire (70) control of handle control; Or the compliance bending occurs or/and prefabricated deformation is set in described guiding catheter (7);

Described guiding catheter (7) is controlled and is not controlled by handle by guiding catheter control handle (27) or joystick (2).

2. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: the far-end of described catheter body section (4) is the controllable bending tune (5) that is connected of the section of comprising and melt (6) near-end also, and it is crooked or/and prefabricated deformation is set that compliance occurs described controllable bending tune (5); Described guiding catheter (7) also comprises independent the setting or the not independent guiding catheter control handle (27) that arranges.

3. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: described ablation catheter (1) or/and joystick (2) or/and sensor (92) also is installed on the guiding catheter (7).

4. kidney according to claim 2 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: sensor (92) also is installed on the described guiding catheter control handle (27).

5. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: link to each other at near-end between the described absolute construction (8), comprise three kinds of forms between two absolute construction (8): the far-end of two absolute construction (8) connects as one and consists of and melt paragraph header end (17); Perhaps two absolute construction (8) far-end is separated from each other independently of one another; Perhaps the mid portion of two absolute construction (8) links together, and far-end is separated from each other again.

6. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: when guiding catheter (7) is ablation catheter (1) when deformation provides fulcrum, the inclined hole (74) that the head setting of guiding catheter (7) communicates with blood vessel is or/and side channel (76).

7. kidney goes to sympathetic nerve radio frequency ablation catheter system according to claim 1 or 5, it is characterized in that:

Connect as one when the far-end of absolute construction (8) and consist of when melting paragraph header end (17), the guiding catheter head end arranges throat structure (73) or plug (72), and side channel (76) is set on the head side wall of guiding catheter (7);

When absolute construction (8) when being separated from each other independently of one another, inclined hole (74) is set on the head end of guiding catheter (7) or the head side wall;

When the mid portion of absolute construction (8) links together, when far-end is separated from each other again, the inclined hole (74) that the head end of guiding catheter (7) or head side wall setting communicate with blood vessel, inclined hole (74) arrange side channel (76) on the sidewall of guiding catheter (7) afterwards again.

8. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: when guiding catheter (7) is not ablation catheter (1) when deformation provides fulcrum, absolute construction (8) arranges prefabricated deformation.

According to claim 1 or 7 described kidneys go to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: comprise that also controllable bending tune (5) arranges prefabricated deformation.

10. described kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: also be provided with on the afterbody sidewall of described guiding catheter (7) for connecting syringe or priming device and carry out the perforate (77) of injection in the blood vessel or injection Intravascular contrast agents, or carry out blood vessel in injection or/and inject Intravascular contrast agents with syringe or/and priming device links to each other by guiding catheter (7) end openings; Or/and described guiding catheter (7) end arranges jointing (76), jointing (76) is connected with syringe, priming device, ablation catheter (1) or joystick (2).

11. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: described ablation catheter (1) or/and guiding catheter (7) when making by selecting the material of different hardness, or by optionally reducing or/and increase the internal structure of catheter segment or/and the structure of tube wall.

12. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: described ablation catheter (1) is or/and the upper reference mark of guiding catheter (7), with indication ablation catheter (1) or/and the degree of depth of guiding catheter (7) intravasation and length, the width of under ultrasonic or X ray image equipment, indirectly measuring organization of human body; Ablation catheter (1) is or/and arrange different developing marks for distinguishing ablation catheter (1) or/and guiding catheter (7) under ultrasonic or X ray image equipment on the guiding catheter (7); Or/and being set on each absolute construction (8), different developing marks is used under ultrasonic or X ray image equipment, distinguishing different absolute construction (8); Ablation catheter (1) is used for distinguishing different axial-rotation states or/and labelling also is set on the guiding catheter (7) under ultrasonic or X ray image equipment.

13. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: ablation catheter (1) is fixing with joystick (2) upper end by catheter body section (4), the lower end of joystick (2) or downside have energy exchange joint (201), and the center cavity that passes joystick (2) from the wire, conduit, microwave antenna or the optical fiber that melt head (9) compiles at described energy exchange joint (201).

14. according to claim 1 or 13 described kidneys go to sympathetic nerve radio frequency ablation catheter system, it is characterized in that:

Described joystick (2) comprises lever (241) or/and lever (271); Or described joystick (2) only comprises lever (217);

Be provided with control knob (237) or console panel (238) for the deformation of control controllable bending tune (5) on the lever (271), described control knob (237) or console panel (238) are connected with guide wire (11), by moving up and down of control knob (237), or pass through the multiple-directional rotating realization of console panel (238) to the control of controllable bending tune; Or/and comprise annular control knob (250), described annular control knob (250) is connected with ablation catheter (1) by connecting rod (251), described connecting rod (251) is arranged in the gathering sill (244) of joystick (2), by moving up and down annular control knob (250), realize the control to absolute construction (8); Also comprise the buffer structure that can prevent excessive tractive;

Described guiding catheter control handle (27) comprises lever (271') and lever (273), be provided with control knob (237') or console panel (238') for the deformation of control guiding catheter (7) on the lever (271'), described control knob (237') or console panel (238') are connected with guide wire (11), by moving up and down of control knob (237'), or pass through the multiple-directional rotating realization of console panel (238') to the control of guiding catheter (7); Also comprise the buffer structure that can prevent excessive tractive; Described guiding catheter control handle (27) comprises with joystick (2) can take off groove tooth slide construction, can take off groove tooth slide construction by the draw-in groove (293) on the lever (273), cone cylinder groove (292), snap ring (297), hole clipping (299) and lever (241) but on pressure hook shape structure (242), cone cylinder give prominence to tenon (243), break and combination by taking off groove tooth slide construction.

15. kidney according to claim 1 goes to sympathetic nerve radio frequency ablation catheter system, it is characterized in that: the described generating means (3) that melts is provided with the joint of energy output and the joint (311) of sensor signal input, also is provided with simultaneously and external power supply phase ground joint (321); Described melt generating means (3) contain by carry out touch screen control parameter and partly or entirely information can show thereon display (320) and the button (330) of adjusting parameter.