CN103221688A - A chromatography pump - Google Patents
A chromatography pump Download PDFInfo
- Publication number
- CN103221688A CN103221688A CN2011800573737A CN201180057373A CN103221688A CN 103221688 A CN103221688 A CN 103221688A CN 2011800573737 A CN2011800573737 A CN 2011800573737A CN 201180057373 A CN201180057373 A CN 201180057373A CN 103221688 A CN103221688 A CN 103221688A
- Authority
- CN
- China
- Prior art keywords
- pump
- piston
- outlet
- cylinder head
- valve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/16—Casings; Cylinders; Cylinder liners or heads; Fluid connections
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B11/00—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation
- F04B11/0008—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using accumulators
- F04B11/0033—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using accumulators with a mechanical spring
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/06—Venting
Abstract
The invention relates to a chromatography pump, comprising a cylinder (202, 402) in which a piston (204, 404) is arranged for a reciprocating movement; a front element (208) provided with a cylinder head area (210) which together with the cylinder (202, 402) and the piston (204, 404) defines a cylinder space (212); an inlet valve (214) and an outlet valve (216) arranged in the front element (208); an inlet channel (218) arranged in the front element (208) between the inlet valve (214) and the cylinder head area (210); an outlet channel (220) arranged in the front element (208) between the cylinder head area (210) and the outlet valve (216). The inlet channel (218) and outlet channel (220) extend in a substantially straight direction, so that air bubbles (234) are prevented from being trapped within the inlet and outlet channels (218, 220).
Description
Technical field
The present invention relates to chromatogram pump according to the preamble of claim 1.
Chromatographic analysis is to be used for discerning and quantitatively to remain on the component of sample and also be used for the chemical process of the purification and the extraction of component.In this process, the component in the solution is separated from one another when solution moves through the static material that remains in the tower.
Solution by the pumping under high pressure of one or several chromatogram pumps by the static material in the tower.
Background technique
In chromatographic analysis and especially liquid chromatography are analyzed, usually only can obtain the sample of the material of very little to be analyzed or purification.The process during the mixing gradient of two kinds of different liquids also to solution when it moves through static material in the tower flow and the quick variation sensitivity of pressure.For this reason, the chromatogram pumping system must be very accurate, so that realize from the stream output of chromatogram pump and the minimal ripple of pressure.
When preparing the chromatographic analysis process, must remove the air that remains in the chromatogram pump.In addition, must remove the air that remains in the sample.Therefore, the chromatogram pumping system usually is provided with and removes the cleaning device that remains on the air in the chromatogram pump when process begins.Cleaning device produces vacuum at delivery side of pump valve place, make to remain on that air from pump in the pump is sucked out and solution or sample are inhaled in the pump simultaneously.
Yet bubble tends to be trapped within the chromatogram pumping cylinder to a certain extent, even cleaning device has been removed the main volume of the air that remains in the chromatogram pump.The bubble that is trapped in the chromatogram pump has reduced the chromatogram pump performance, makes the pressure of solution and flow to fluctuate.This will influence overall chromatographic analysis mixed process, make to realize more coarse result.
Hereinafter in the prior art that will describe in more detail in conjunction with Fig. 1 in the obtainable chromatogram pump, bubble tends to be trapped within the entrance and exit passage of pump and in the cylinder.Bubble is trapped within the stagnant area, that is, and and edge in being formed at known pump and bight.
Summary of the invention
An object of the present invention is to realize having the chromatogram pump of automatic removing, it has eliminated the manual operating device that is used for clear operation.
Another object of the present invention is to realize helping bubble to be transferred chromatogram pump by pump.
Another purpose of the present invention is to realize preventing that bubble is trapped within chromatogram pump wherein.
Another purpose of the present invention is to realize the stream output of chromatogram pump and the minimal ripple of pressure.
These purposes realize by the chromatogram pump according to claim 1.
Because inlet channel and outlet passage extend along basic rectilinear direction, thereby do not exist the bubble can be in edge in this is trapped within passage or bight.But bubble will not influence the chromatogram pump performance by passage.Therefore, realized having high performance chromatogram pump.
According to an aspect of the present invention, the outlet that is arranged in the inlet channel in the cylinder head zone has basic elliptical configuration.This configuration helps bubble and is transferred exit and entrance and further arrives outlet passage.
According to another aspect of the invention, cavity is arranged in the cylinder head zone and the inlet of outlet passage is arranged in this cavity.Thus, bubble and the bubble in the cylinder from inlet channel will be easy to be transferred out outlet passage.
According to another aspect of the invention, cavity has and corresponds essentially to arc shape.This configuration helps bubble is transferred out outlet passage.
According to another aspect of the invention, front elements is made by PEEK material, titanium or Hastelloy (hastelloy).Thus, realized the high strength of front elements.In addition, the surface properties of these materials can be suitable for preventing that bubble is trapped and attached on the surface in the passage neutralization tank.
According to another aspect of the invention, the surface roughness (Ra) of the wall in the wall of inlet channel and outlet passage and cylinder head zone is between 0.2-2.0, preferably between 1.0-2.0.This will prevent that bubble is attached to the surface of the wall in inlet channel and outlet passage and cylinder head zone.
According to another aspect of the invention, inlet valve and outlet valve are to be provided with a safety check of the ball of putting, and the weight that wherein is arranged on the ball forces ball against seat portion.Thus, prevented that bubble is owing to the power from the ball in the seat portion is trapped between ball and the seat portion.In addition, between the inwall of ball and valve, the capillary force that is caused by bubble is stuck on the inwall ball.This prevents by the weight that is arranged on the ball.
According to another aspect of the invention, the cylinder head zone has the normal that overlaps substantially with the axis of piston.Therefore, realized the compact design in cylinder space.Because inlet channel and outlet passage are connected to the normal in cylinder head zone and cylinder head zone and overlap substantially with the axis of piston, thereby the bubble in the cylinder will be easy to be transferred out outlet passage.
Description of drawings
Many-sided, advantage of the present invention and feature can draw with reference to the detailed description of accompanying drawing to exemplary embodiment of the present invention from following.
Fig. 1 illustrates the diagram sectional view of prior art chromatogram pump;
Fig. 2 illustrates the sectional view according to the preferred embodiment of chromatogram pump of the present invention;
Fig. 3 illustrates the front view according to the preferred embodiment of chromatogram pump of the present invention;
Fig. 4 illustrates the sectional view according to second embodiment of chromatogram pump of the present invention;
Fig. 5 illustrates the sectional view according to the 3rd embodiment of chromatogram pump of the present invention; And
Fig. 6 illustrates the amplification sectional view that is used for according to the 4th embodiment of the piston of chromatogram pump of the present invention.
Embodiment
Fig. 1 illustrates the diagram sectional view of prior art chromatogram pump 101, and this chromatogram pump 101 comprises cylinder 102, and piston 104 is arranged in wherein to move back and forth.Moving back and forth by the drive unit 106 such as motor of piston 104 produces.Front elements 108 is provided with cylinder head zone 110, and it limits cylinder space 112 together with cylinder 102 and piston 104.The inlet valve 114 and the outlet valve 116 that are the safety check form are arranged in the front elements 108.Inlet channel 118 is arranged in the front elements 108 between inlet valve 114 and cylinder head zone 110, and outlet passage 120 is arranged in the front elements 108 between cylinder head zone 110 and outlet valve 116.When piston 104 in Fig. 1 direction moves left the time, remain on liquid 122 in the schematically disclosed container 124 because the vacuum that piston 104 produces and being inhaled in the cylinder space 112 through inlet valve 114 and inlet channel 118 in cylinder space 112.When the vacuum that is produced when inlet valve 114 sucks liquid 122, the balls 126 in the valve 114 promote and open the path that is used for liquid 122 between ball 126 and the seat portion 128 by liquid stream from seat portion 128.Simultaneously, owing to ball 126 seals against seat portion 128, thereby prevented that liquid 122 from entering outlet valve 116.
When piston 104 after this change direction and along among Fig. 1 when right moves, liquid 122 is forced out from cylinder space 112 and because the pressure that produces cylinder space 112 of piston 104 and being forced out from outlet valve 116 through outlet passage 120.Liquid flows to static material 132 from outlet valve 116 and is maintained at wherein schematically disclosed tower 130.The liquid that has been sent to tower 130 is drawn towards waste material container 131 or distillate collector from tower 130.When pressure was pressed press liquid 122 by outlet valve 116, the ball 126 in the valve 116 promoted and opens the path that is used for liquid 122 between ball 126 and the seat portion 128 by the stream of liquid 122 from seat portion 128.Simultaneously, owing to ball 126 seals against seat portion 128, thereby liquid 122 effusion inlet valves 114 have been prevented.
Yet bubble 134 tends to be trapped among Fig. 1 in the disclosed known chromatogram pump 101, especially in the inlet channel 118 of pump 101 and outlet passage 120 and in the cylinder space 112.The reason that bubble 134 is trapped within inlet channel 118 and the outlet passage 120 is that passage 118,120 is provided with the stagnant area, for example edge and bight 136.Another reason is that the surface roughness of wall surface of passage is too level and smooth, and this helps bubble 134 and is attached to the surface.Similarly shortcoming can see 110 places, cylinder head zone in cylinder space 112.Bubble 134 also can be trapped between the ball 126 and seat portion 128 in inlet valve 114 and the outlet valve 116.The bubble 134 that is trapped can prevent that also ball 126 is owing to capillary force returns a portion 128.
As mentioned above, be trapped within the performance that chromatogram pump 101 interior bubbles 134 have reduced pump 101, make the pressure of liquid 122 and flow to fluctuate.This will influence overall chromatographic analysis process, make to realize more coarse result.
Fig. 2 illustrates the sectional view according to the preferred embodiment of chromatogram pump 201 of the present invention.Chromatogram pump 201 comprises cylinder 202, and piston 204 is arranged in wherein to move back and forth along axis 248.Seal arrangement 205 is arranged on the piston 204, makes that the leakage between piston 204 and the cylinder 202 is reduced to greatest extent.Moving back and forth by the drive unit 206 such as motor of piston 204 produces.Front elements 208 is provided with cylinder head zone 210, and it limits cylinder space 212 together with cylinder 202 and piston 204.The inlet valve 214 and the outlet valve 216 that are the safety check form are arranged in the front elements 208.Inlet channel 218 is arranged in the front elements 208 between inlet valve 214 and cylinder head zone 210, and outlet passage 220 is arranged in the front elements 208 between cylinder head zone 210 and outlet valve 216.When piston 204 in Fig. 2 direction moves left the time, remain on liquid 222 in the schematically disclosed container 224 because the vacuum that piston 204 produces and in inlet valve 214 and inlet channel 218 suction cylinder spaces 212 in cylinder space 212.When the vacuum that is produced when inlet valve 214 sucks liquid 222, the ball 226 in the valve 214 promotes and opens the path that is used for liquid 222 between ball 226 and the seat portion 228 by the stream of liquid 222 from seat portion 228.Simultaneously, owing to ball 226 seals against seat portion 228, thereby prevented that liquid 222 from entering outlet valve 216.When the pumping process began, cylinder 202, passage 218,220 and valve 214,216 were filled with air.Therefore, during special time period, air will be pumped out by moving back and forth from cylinder 202, passage 218,220 and valve 214,216 of piston 204.Therefore, chromatogram pump 201 according to the present invention is self-purging.
When piston 204 after this change direction and along among Fig. 2 when right moves, liquid 222 is forced out from cylinder space 212 and because the pressure that produces cylinder space 212 of piston 204 and being forced out from outlet valve 216 through outlet passage 220.Liquid 222 flows to static material 232 from outlet valve 216 and is maintained at wherein schematically disclosed tower 230.The liquid that has been sent to tower 230 is drawn towards waste material container 231 or distillate collector from tower 230.When pressure was pressed press liquid 222 by outlet valve 216, the ball 226 in the valve 216 promoted and opens the path that is used for liquid 222 between ball 226 and the seat portion 228 by the stream of liquid 222 from seat portion 228.Simultaneously, owing to ball 226 seals against seat portion 228, thereby liquid 222 effusion inlet valves 214 have been prevented.According to the pressure of chromatogram pump 201 of the present invention and the example of piston swept volume is 200bar and 125 μ l.The flow that pump produces is in 0-60ml/ minute scope.
Inlet channel 218 among Fig. 2 and outlet passage 220 extend not having sharp edges or bight or have the basic rectilinear direction in the situation lower edge in the least possible sharp edges or bight, make to have prevented that bubble 234 is trapped within the passage 218,220.Passage 218,220 is not provided with the stagnant area, for example edge and bight, and therefore bubble 234 can not be trapped within the passage.But bubble 234 will not influence the performance of chromatogram pump 201 by passage 218,220.In addition, outlet passage favours axis 248 and extends, as in the drawings as seen.In other words, outlet passage 218 and 220 provides in cylinder head zone 210 and has been connected with basic straight line between their valves 214 and 216 separately, and this straight line is with respect to axis 248 inclinations of piston 204 and have divergencing path.Therefore, utilize this layout of chromatogram pump 201, realized high-performance.Passage 218 and 220 configuration provide improved flow, and help the cleaning of pump 201.This is particularly important when different liquids is used for pump 201.When the liquid of pumping is treated in change, in the prior art generally bubble be trapped within the pump.In pump in accordance with the present invention 201, bubble 234 unlikely is trapped and pump 201 will be removed automatically.
The surface roughness (Ra) of the wall 236 of inlet channel 218 and outlet passage 220 and the wall 238 in cylinder head zone 210 is between 0.2-2.0, preferably between 1.0-2.0.This will prevent that bubble 234 is attached to the wall 236 of inlet channel 218 and outlet passage 220 and the wall 238 in cylinder head zone 210.Surface roughness can realize by special processing technique.Front elements 208 is preferably made by PEEK material, titanium or Hastelloy.Other material also is possible.PEEK and Hastelloy are TM trade mark.Thus, realized the high strength of front elements 208.In addition, the surface properties of these materials can be suitable for above-mentioned surface roughness value.Liquid 222 must under high pressure be pumped through the static material 232 in the tower 230.Therefore, the material that is used for front elements 208 must have high strength properties.
Fig. 3 illustrates the front view according to the preferred embodiment of chromatogram pump 201 of the present invention.Cavity 242 is arranged in the cylinder head zone 210, and the outlet 240 of inlet channel 218 is arranged in the bottom of cavity 242.In addition, the inlet 244 of outlet passage 220 is arranged in the cavity 242.Thus, bubble 234 and the bubble 234 in the cylinder space 212 from inlet channel 218 will be easy to transfer out outlet passage 220.Preferably, cavity 242 has and corresponds essentially to arc shape, and the inlet 244 of outlet passage 220 has conical form.This configuration helps bubble 234 is transferred out outlet passage 220.Yet, the outlet 240 of inlet channel 218 might be arranged in cavity 242 outsides.
Fig. 4 illustrates the sectional view according to second embodiment of chromatogram pump 301 of the present invention.To have same numeral with disclosed similar member among Fig. 2.Inlet valve 214 and outlet valve 216 are provided with the ball 226 that seat is put, and wherein weight 303 is arranged on the ball 226, and this weight 303 forces ball 226 against seat portion 228.Thus, prevented that bubble 234 is owing to the power from the ball in the seat portion 228 226 is trapped between ball 226 and the seat portion 228.In addition, prevented that ball 226 is stuck on the inwall of valve 214,216 owing to capillary force.Therefore weight 303 is subjected to gravity effect, must be along making weight 303 rest on the direction installation on the ball 226 in the valve 214,216 according to this second embodiment's pump 301.Combine as an alternative or with weight 303, also spring (unexposed) may be arranged in the valve 214,216, it forces ball 226 against seat portion 228.
Fig. 5 illustrates the sectional view according to the 3rd embodiment of chromatogram pump 301 of the present invention.To have same numeral with disclosed similar member among Fig. 3.According to this embodiment, outlet passage 220 and inlet valve 214 and outlet valve 216 extend along the basic direction that overlaps, and make pump 301 can be mounted to outlet passage 220 and are in basic vertical direction about horizontal plane 308.Therefore, the bubble 234 in the pump 301 will leave outlet passage 220 easily owing to the gravity that influences the bubble 234 in the liquid.
Fig. 6 illustrates the amplification sectional view that is used for according to the 4th embodiment of the piston 404 of chromatogram pump 401 of the present invention.Piston 404 is provided with circumferential seal 405, and it by circumferential sheet spring 407 spring-loaded, make to realize the tight seal between cylinder 402 and the piston 404 on the radially outward direction.The stopper 409 that preferably is made of titanium is arranged on the end 411 of piston 402.Stopper 409 is attached to piston 404 and Sealing 405 is fixed on the end 411 of piston 404.
Chromatogram pump 201,301,401 according to the present invention mainly is designed for pumping liquid 222.Yet other fluid also can be by chromatogram pump 201,301,401 pumpings according to the present invention.
Claims (13)
1. chromatogram pump, comprising: cylinder (202,402), piston (204,404) are arranged in wherein to move back and forth along axis (248); Be provided with the front elements (208) of cylinder head zone (210), described cylinder head zone (210) limits cylinder space (212) together with described cylinder (202,402) and described piston (204,404); Be arranged in inlet valve (214) and outlet valve (216) in the described front elements (208); Between described inlet valve (214) and described cylinder head zone (210), be arranged in the inlet channel (218) in the described front elements (208); Between described cylinder head zone (210) and described outlet valve (216), be arranged in the outlet passage (220) in the described front elements (208), described chromatogram pump is characterised in that described inlet channel (218) and outlet passage (220) extend along basic rectilinear direction, and is that described inlet channel (218) and outlet passage (220) all favour described axis (248) and extend.
2. pump according to claim 1 is characterized in that, the contiguous described cylinder space of cavity (242) (212) is arranged, and is that the inlet (244) of described outlet passage (220) is arranged in the described cavity (242).
3. pump according to claim 2 is characterized in that, the outlet (240) of described inlet channel (218) is arranged in the described cavity (242).
4. according to claim 2 or 3 described pumps, it is characterized in that described cavity (242) has and corresponds essentially to arc shape, make to prevent that bubble (234) is trapped within the described cavity (242).
5. according to each described pump in the aforementioned claim, it is characterized in that described front elements (208) is made by PEEK material, titanium or Hastelloy.
6. according to each described pump in the aforementioned claim, it is characterized in that the surface roughness (Ra) of the wall (236) of described inlet channel and outlet passage (218,220) is between 0.2-2.0, preferably between 1.0-2.0.
7. according to each described pump in the aforementioned claim, it is characterized in that the surface roughness (Ra) of the wall (238) in described cylinder head zone (210) is between 0.2-2.0, preferably between 1.0-2.0.
8. according to each described pump in the aforementioned claim, it is characterized in that described inlet valve and outlet valve (214,216) are to be provided with a safety check of the ball of putting (226), wherein, the weight (303) that is arranged on the described ball (226) forces described ball (226) against seat portion (228).
9. according to each described pump in the aforementioned claim, it is characterized in that described cylinder head zone (210) has the normal (246) that overlaps substantially with the axis (248) of described piston (204).
10. according to each described pump in the aforementioned claim, it is characterized in that described chromatogram pump (201,301,401) is designed to pumping liquid (222).
11., it is characterized in that circumferential seal (405) is arranged on the described piston (404) according to each described pump in the aforementioned claim, and circumferential sheet spring (407) is arranged to apply the radial load of outside orientation on described Sealing (405).
12. pump according to claim 11, it is characterized in that, stopper (409) is arranged on the end (411) of described piston (404), and described stopper (409) is attached to described piston (404) and described Sealing (405) is fixed on the end (411) of described piston (404).
13. according to each described pump in the aforementioned claim, it is characterized in that, described outlet passage (220) and described inlet valve and outlet valve (214,216) extend along the basic direction that overlaps, make described pump can be mounted to outlet passage (220) and be in basic vertical direction about horizontal plane (308).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1051261 | 2010-11-30 | ||
| SE1051261-4 | 2010-11-30 | ||
| PCT/EP2011/070953 WO2012072494A1 (en) | 2010-11-30 | 2011-11-24 | A chromatography pump |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103221688A true CN103221688A (en) | 2013-07-24 |
Family
ID=45092341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011800573737A Pending CN103221688A (en) | 2010-11-30 | 2011-11-24 | A chromatography pump |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20130259723A1 (en) |
| EP (1) | EP2646686A1 (en) |
| JP (1) | JP2014505194A (en) |
| CN (1) | CN103221688A (en) |
| CA (1) | CA2819114A1 (en) |
| WO (1) | WO2012072494A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107076126A (en) * | 2014-10-13 | 2017-08-18 | 阿尔法有限责任公司 | For fluid product displacement pump and pumping group and use its method |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102013105445B4 (en) † | 2013-05-28 | 2015-08-20 | Pintsch Bubenzer Gmbh | Function unit and electro-hydraulic brake release device with such a |
| CN106104267B (en) * | 2014-03-31 | 2020-11-03 | 安捷伦科技有限公司 | Seal moving with piston in high pressure pump |
| CN105443372B (en) * | 2015-11-26 | 2017-07-14 | 中国南方电网有限责任公司超高压输电公司广州局 | A kind of double acting linear reciprocating pump head |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE850995C (en) * | 1950-11-01 | 1952-09-29 | Albert Ziegler Fa | Hand pump for venting the suction line of a motorized syringe |
| DE1960369A1 (en) * | 1969-12-02 | 1971-06-09 | Siemens Ag | Device for damping the pulsation of a flowing liquid |
| EP0818629A1 (en) * | 1996-07-11 | 1998-01-14 | GETRAG Getriebe- und Zahnradfabrik Hermann Hagenmeyer GmbH & Cie | Hydraulic actuator and process for venting a hydraulic actuator |
| CN1393693A (en) * | 2001-06-29 | 2003-01-29 | 中国科学院大连化学物理研究所 | Low-pulse high-precision efficient liquid-phase chromatographic pump with dual plungers |
| US20050024609A1 (en) * | 2003-06-11 | 2005-02-03 | Asml Netherlands B.V. | Lithographic apparatus and device manufacturing method |
| WO2006012836A2 (en) * | 2004-08-02 | 2006-02-09 | Dionex Softron Gmbh | Device for the refrigerated storage and delivery of samples and an integrated liquid cooling unit that is suitable therefor |
| DE102007050335A1 (en) * | 2007-10-18 | 2009-04-23 | Bayer Technology Services Gmbh | Arrangement and method for providing a preferably time-variable liquid mixture |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2246685A (en) * | 1940-03-27 | 1941-06-24 | Clearing Machine Corp | Piston packing |
| US3049082A (en) * | 1958-05-26 | 1962-08-14 | John W Mecom | Reciprocating pump |
| US3545897A (en) * | 1964-07-08 | 1970-12-08 | Peters & Russell Inc | Pump |
| DE2940606C2 (en) * | 1979-10-06 | 1985-12-19 | Woma-Apparatebau Wolfgang Maasberg & Co Gmbh, 4100 Duisburg | Pump valve head for high pressure pumps |
| DE3111614A1 (en) * | 1981-03-25 | 1982-10-07 | Uhde Gmbh, 4600 Dortmund | "VALVE SET FOR HIGH PRESSURE PUMPS" |
| DE3122091C1 (en) * | 1981-06-03 | 1982-12-16 | Saphirwerk, Industrieprodukte AG Nidau, 2560 Nidau | Submersible piston pump |
| US4467703A (en) * | 1982-08-26 | 1984-08-28 | United States Steel Corporation | Reciprocable pump |
| US4527961A (en) * | 1982-08-26 | 1985-07-09 | United States Steel Corporation | Reciprocable pump having axially pivotable manifold to facilitate valve inspection |
| US4758135A (en) * | 1986-12-30 | 1988-07-19 | Weatherford U.S., Inc. | Pump head |
| US5037277A (en) * | 1989-07-26 | 1991-08-06 | Flow International Corporation | Poppet valve for a high pressure fluid pump |
| US5154589A (en) * | 1990-11-09 | 1992-10-13 | National Instrument Company | Metering pump |
| US5664938A (en) * | 1992-03-05 | 1997-09-09 | Yang; Frank Jiann-Fu | Mixing apparatus for microflow gradient pumping |
| JP3777490B2 (en) * | 1997-01-31 | 2006-05-24 | 株式会社荏原製作所 | Liquid feeding device and control method thereof |
| JP4455713B2 (en) * | 2000-02-21 | 2010-04-21 | 株式会社島津製作所 | Valve unit and liquid feed pump using the same |
| US6623259B1 (en) * | 2002-05-06 | 2003-09-23 | George H. Blume | High pressure plunger pump housing and packing |
| US8147227B1 (en) * | 2000-07-18 | 2012-04-03 | Blume George H | Valve guide and spring retainer assemblies |
| US6382940B1 (en) * | 2000-07-18 | 2002-05-07 | George H. Blume | High pressure plunger pump housing and packing |
| JP2005133647A (en) * | 2003-10-30 | 2005-05-26 | Ebara Corp | Axial piston pump or motor |
| US8221100B2 (en) * | 2008-12-04 | 2012-07-17 | Nlb Corp. | High pressure water pump valve and seal structure |
| JP5533061B2 (en) * | 2009-06-12 | 2014-06-25 | パナソニック株式会社 | Hermetic compressor and refrigeration system |
| US7950322B2 (en) * | 2009-10-09 | 2011-05-31 | Vicars Berton L | Plunger assembly |
-
2011
- 2011-11-24 CA CA2819114A patent/CA2819114A1/en active Pending
- 2011-11-24 US US13/990,754 patent/US20130259723A1/en not_active Abandoned
- 2011-11-24 WO PCT/EP2011/070953 patent/WO2012072494A1/en active Application Filing
- 2011-11-24 JP JP2013541300A patent/JP2014505194A/en active Pending
- 2011-11-24 CN CN2011800573737A patent/CN103221688A/en active Pending
- 2011-11-24 EP EP11790755.0A patent/EP2646686A1/en not_active Withdrawn
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE850995C (en) * | 1950-11-01 | 1952-09-29 | Albert Ziegler Fa | Hand pump for venting the suction line of a motorized syringe |
| DE1960369A1 (en) * | 1969-12-02 | 1971-06-09 | Siemens Ag | Device for damping the pulsation of a flowing liquid |
| EP0818629A1 (en) * | 1996-07-11 | 1998-01-14 | GETRAG Getriebe- und Zahnradfabrik Hermann Hagenmeyer GmbH & Cie | Hydraulic actuator and process for venting a hydraulic actuator |
| CN1393693A (en) * | 2001-06-29 | 2003-01-29 | 中国科学院大连化学物理研究所 | Low-pulse high-precision efficient liquid-phase chromatographic pump with dual plungers |
| US20050024609A1 (en) * | 2003-06-11 | 2005-02-03 | Asml Netherlands B.V. | Lithographic apparatus and device manufacturing method |
| WO2006012836A2 (en) * | 2004-08-02 | 2006-02-09 | Dionex Softron Gmbh | Device for the refrigerated storage and delivery of samples and an integrated liquid cooling unit that is suitable therefor |
| DE102007050335A1 (en) * | 2007-10-18 | 2009-04-23 | Bayer Technology Services Gmbh | Arrangement and method for providing a preferably time-variable liquid mixture |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107076126A (en) * | 2014-10-13 | 2017-08-18 | 阿尔法有限责任公司 | For fluid product displacement pump and pumping group and use its method |
| CN107076126B (en) * | 2014-10-13 | 2020-07-07 | 阿尔法有限责任公司 | Volumetric pump and pumping group for fluid products and method for using same |
| US11053930B2 (en) | 2014-10-13 | 2021-07-06 | Alfa S. R. L. | Positive-displacement pump and pumping group for fluid products and method for the use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012072494A1 (en) | 2012-06-07 |
| US20130259723A1 (en) | 2013-10-03 |
| CA2819114A1 (en) | 2012-06-07 |
| EP2646686A1 (en) | 2013-10-09 |
| JP2014505194A (en) | 2014-02-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103221688A (en) | A chromatography pump | |
| CN101166581B (en) | Dosing head for dispensing a fluid from a container | |
| CN104053907A (en) | Piston pump for a high-pressure cleaning device | |
| CN101258325A (en) | Piston pump with improved piston | |
| US7682129B2 (en) | Filtration device combined with self-priming pump | |
| CN106414192B (en) | Discharge valve with a receiving element | |
| CN106232020A (en) | Aspirator | |
| CN206874446U (en) | Plunger pump | |
| JP2015510134A5 (en) | ||
| US8529223B2 (en) | Dual diaphragm pump assembly for a sanitation system | |
| EP3187729A2 (en) | Fluted piston components for pumps | |
| CN103492781A (en) | Method to prevent debris build-up on reciprocating air motor pilot valves | |
| US10046255B1 (en) | Dual filter pump assembly | |
| JP6381540B2 (en) | Flow type analyzer and waste liquid separation method | |
| US20100046320A1 (en) | Shot Pump and Variable-Speed-Type Two-Liquid Metering and Mixing Apparatus | |
| JP6329131B2 (en) | Sample injection device for flow analysis device, flow analysis device, and hemoglobin component measurement method | |
| JP7350724B2 (en) | Piston rod sealing system for reciprocating machines and methods of sealing such piston rods | |
| EP2730826A1 (en) | Cap for cooperating with a flow control element of a valve for a self-priming electric pump | |
| CN110892263B (en) | Plunger pump | |
| CN108612852B (en) | Valve seat and valve structure | |
| RU130231U1 (en) | Degasser | |
| US4664606A (en) | Reciprocating pump for fluids, specifically such contaminated by solids | |
| CN1158166A (en) | Method for analysis and device for carrying out the method | |
| JP5280721B2 (en) | Reciprocating pump with automatic degassing mechanism | |
| US9702793B2 (en) | Variable volume sample capture device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130724 |