CN104983395A - Intraocular pressure real-time measuring apparatus and method based on conjunctival sac pressure detection - Google Patents

Intraocular pressure real-time measuring apparatus and method based on conjunctival sac pressure detection Download PDF

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Publication number
CN104983395A
CN104983395A CN201510260814.3A CN201510260814A CN104983395A CN 104983395 A CN104983395 A CN 104983395A CN 201510260814 A CN201510260814 A CN 201510260814A CN 104983395 A CN104983395 A CN 104983395A
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intraocular pressure
pressure
air bag
signal
real
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CN104983395B (en
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李贵刚
张虹
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Tongji Medical College of Huazhong University of Science and Technology
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Tongji Medical College of Huazhong University of Science and Technology
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Abstract

The invention relates to an intraocular pressure real-time measuring apparatus and method based on conjunctival sac pressure detection. The apparatus comprises a detection head disposed inside the conjunctival sac of a patient, and a signal receiver. The detection head comprises an air bag, and an air pressure sensor and a flexible circuit board both disposed inside the air bag. The air pressure in the air bag is the standard atmospheric pressure, the air bag is in contact with an eyeball, and the air bag is in a pressed state. The flexible circuit board is used for sensing the air pressure in the air bag, converting the air pressure into electric signals, and sending the electric signals. The signal receiver is used for receiving the signals sent by the flexible circuit board. According to the method, the air pressure sensor in the air bag senses the air pressure signals generated as the air bag is subjected to the intraocular pressure, the air pressure signals are converted into the electric signals, then the electric signals are sent out, and the signal receiver processes the signals after receiving the electric signals so as to obtain the real-time intraocular pressure value of the patient. The apparatus and the method are simple in structure, can automatically detect the intraocular pressure value of the patient in a real-time manner, facilitates a doctor in timely making a treatment scheme, and improves the treatment efficiency.

Description

Based on intraocular pressure real-time measurement apparatus and the method for conjunctival sac pressure detecting
Technical field
The present invention relates to the measurement of intraocular pressure, refer to the real-time tonometry device and method based on conjunctival sac pressure detecting particularly.
Background technology
Glaucoma is second-biggest-in-the-world diseases causing blindness, and raise with pathologic intraocular pressure, irreversibility optic atrophy, defect of visual field is feature.In China, glaucoma sickness rate is 0.21%-1.64%, blind rate 10%-20%, is deputy irreversible blinding oculopathy.
Intraocular pressure is the size that eyeball content (aqueous humor, crystalline lens, vitreous body, blood) acts on unit volume wall of eyeball pressure.Intraocular pressure has 24h day and night fluctuation, and intraocular pressure raises for a long time and day and night fluctuation increase will cause optic nerve ischemia, neurodegeneration, and the picture signal changed by retina can not be delivered to brain occipital lobe visual centre smoothly, causes irreversibility defect of visual field.
Therefore finding as early as possible and control intraocular pressure, reducing intraocular pressure day and night fluctuation amplitude, is slow down the definite treatment means that glaucoma disease continues deterioration at present.Therefore, realize 24 hours continuous measurement intraocular pressures be early discovery intraocular pressure abnormal need the problem of solution badly, and lack reliable instrument and equipment at present to realize 24 hours continuous measurement intraocular pressures.
At present, traditional tonometry comprises and refers to survey method, directly ophthalmic measurement method and tonometer detection method.Due to the impact of accuracy and safety, refer to that survey method and the direct method of measurement seldom use clinical.And the instrument of indirect inspection intraocular pressure---tonometer becomes the requisite instrumentation of tonometry owing to possessing accurate, noninvasive feature, conventional intraocular pressure in respect of: Goldmann planishing type tonometer, indentation tonometers, non-contact tonometer etc.But existing tonometer has following deficiency: 1) portable performance is low, need patient's timing repeatedly to hospital's repetition measurement intraocular pressure, measuring process expends huge manpower financial capacity's resource.2) operation need be completed by the ophthalmologist of specialty, and measuring process is loaded down with trivial details.3) use narcotics or instrument contacts cornea, easily cause the coup injury of cornea.And these gauges all only can single measurement intraocular pressure, the fluctuation of long-term intraocular pressure cannot be monitored, thus easily fail to pinpoint a disease in diagnosis some early-stage glaucomas patient.And the method that can realize long term monitoring intraocular pressure at present needs underwent operative implanted sensor, this is that one has traumatic operation, applies because which limit it.As: (the Carter.C.Collins.Miniature passive pressure transensor forimplanting in the eye.IEEE transaction on bio-medicalengineering.1967:4 such as scleral band button tonometer, intraocular pressure sensor tonometer, 14,2; P.-Jui.Chen.Implantable Wireless IntraocularPressure Sensors.IEEE.2008; )
Therefore, be badly in need of a kind of safety, accurate, seriality intraocular pressure monitoring device clinically, make ophthalmologist can make glaucomatous diagnosis more early stage, objective, all sidedly, make invisible glaucoma patient and anti-glaucoma surgery patient can accept in early days more rationally, more effectively to treat.
Summary of the invention
In order to overcome the above-mentioned weakness of existing intraocular pressure monitoring device, the invention provides a kind of mode indirect inspection intraocular pressure based on conjunctival sac pressure detecting, the method can realize safety, accurate, long-range, portable intraocular pressure monitoring.
The technical scheme realizing the object of the invention employing is a kind of intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting, and this device comprises the detection head and signal receiver that load patients conjunctival's capsule;
Described detection head comprises air bag and the baroceptor be located in air bag and flexible PCB, and the air pressure in described air bag is normal atmosphere, and air bag contacts with eyeball, and is in pressured state; Described flexible PCB sends for responding to described air bag internal gas pressure and air pressure being converted to the signal of telecommunication;
Signal receiver, for receiving the signal that described flexible PCB sends.
In technique scheme, the two ends of described air bag are respectively equipped with carves type connector, connect two carve type connector after, described balloon occlusion, and described flexible PCB switches on power.
Further, described flexible PCB comprises:
Pressure transducer, for detecting the intraocular pressure value of air bag induction; And
Processor, is converted to the signal of telecommunication for the intraocular pressure value detected by described pressure transducer;
Signal projector, for outwards launching the described signal of telecommunication.
In technique scheme, the described intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting also comprises:
Memorizer, for receive and store described signal projector launch signal.
In technique scheme, the described intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting also comprises:
Printer, is connected with described memorizer, for the data in print memory.
In addition, the present invention also provides a kind of method being measured intraocular pressure by said apparatus in real time, and the method comprises:
Detection head is loaded measured's conjunctival sac, air bag is contacted with eyeball, and air bag is in pressured state;
With the current intraocular pressure of tonometer test measured, obtain the current intraocular pressure value of measured, this test value is intraocular pressure reference value;
The atmospheric pressure value detected is converted to the signal of telecommunication and sends by the flexible PCB be located in air bag;
Signal receiver receives the signal of telecommunication that flexible PCB sends, and obtains intraocular pressure value according to the signal of telecommunication, corrects, thus obtain real-time intraocular pressure value according to reference value to this intraocular pressure value.
Further, the omnidistance intraocular pressure wave pattern stored in memorizer is printed display by printer.
The air pressure signal that the inventive method is produced because being subject to intraocular pressure by the pressure transducer induction air bag in air bag, and send after this air pressure signal is converted to the signal of telecommunication, signal receiver is received the laggard signal processing excessively of the signal of telecommunication and is obtained the real-time intraocular pressure value of patient.Structure of the present invention is simple, the intraocular pressure value of patient can be detected in real time, automatically, be conducive to doctor and make therapeutic scheme in time, improves therapeutic efficiency.
Accompanying drawing explanation
Fig. 1 is the structural representation of the intraocular pressure real-time measurement apparatus that the present invention is based on conjunctival sac pressure detecting.
Fig. 2 is the using state schematic diagram of the intraocular pressure real-time measurement apparatus that the present invention is based on conjunctival sac pressure detecting.
Fig. 3 is the flow chart of the intraocular pressure method for real-time measurement that the present invention is based on conjunctival sac pressure detecting.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, the present invention is described in further detail.
As shown in Figure 1, the intraocular pressure real-time measurement apparatus that the present invention is based on conjunctival sac pressure detecting comprises detection head 1 and signal receiver.The structure of detection head 1 as shown in Figure 1, comprise air bag 2, be provided with flexible PCB 3 and pressure transducer 4 in air bag 2, pressure transducer 4 is connected with flexible PCB 3, pressure transducer 4 detects the air pressure in air bag, and the air pressure signal detected is transferred to flexible PCB 3.The two ends of air bag 2 are respectively equipped with carves type connector 5, connect two carve type connector 5 after, the conductive switch 6 of flexible PCB 3 is connected, and air bag 2 is closed.The present embodiment flexible PCB 3 used comprises processor and signal emission module, and the air pressure signal that pressure transducer detects is converted to the signal of telecommunication by processor, and the signal of telecommunication after conversion is outwards launched by signal emission module.
Due to air bag in its natural state its internal pressure be atmospheric pressure, now pressure transducer 4 no-output.Pressured state is in after air bag 2 loads conjunctival sac, as shown in Figure 2, the pressure change that pressure transducer 4 will detect in air bag 2.When intraocular pressure changes, size and the hardness of eyeball can be changed, and detection head 1 is owing to being subject to the fixation of conjunctival sac, position is relatively fixing, the size of eyeball and the change of hardness can produce different pressure to air bag 2, thus change the air pressure of air bag 2 inside, now pressure transducer 4 just can detect the air pressure signal of transformation.
The signal of telecommunication that signal receiver Received signal strength transmitter module is launched, through signal processing, obtains the force value corresponding to air pressure signal that pressure transducer detects.For the ease of storing data, signal receiver is also connected with memorizer, and the signal that memorizer Received signal strength emitter is launched also stores.Immediately obtain the intraocular pressure information of patient for the ease of medical personnel, the present invention can also arrange the computer that is connected with printer, and computer is also connected with memorizer, exports the data in memorizer to printer and prints.
The process of intraocular pressure is measured in real time as shown in Figure 3 by above-mentioned intraocular pressure real-time measurement apparatus.
Type connector is carved at S1, connection detection head 1 two ends, flexible PCB 3 in detection head 1 is connected, and forms the detection air bag closed, and namely detection head 1 enters duty, at this moment the pressure in air bag 2 can be approximately normal atmosphere (An), and the Signal aspects current gas pressure received by signal receiver is zero.
S2, be installed in measured's conjunctival sac by detection head 1, now air bag 2 contacts with eyeball, and is in pressured state.
S3, due to air bag 2 pressurized, at this moment signal receiver should be shown as the current intraocular pressure of measured according to received signal.But owing to being subject to the impact of the factor such as detection head installation site and measured's eyelid thickness, hardness, and the difference of individual physiological structure or detection head present position, detection head 1 can export different intraocular pressure values, current intraocular pressure value shown by receiver and actual intraocular pressure value misfit, and at this moment need to detect the current intraocular pressure value of eyeball by third party's detection means.
Therefore, this step tonometer measures the current intraocular pressure value of eyeball 7, this tonometry value is the equilibrium point of air bag internal gas pressure, and using this equilibrium point as zero, when eyeball pressure increase or when declining, air bag internal gas pressure rises thereupon or declines.
S4, correct according to the tonometry value detected in step S3, namely signal receiver is using the datum mark of tonometry value as this testing process.
S5, pressure transducer are detected different atmospheric pressure values and are sent by the signal emission module in detection head 1, after signal receiver receives the sent signal of telecommunication, through the real-time intraocular pressure value that signal processing finally obtains in different time sections.
The real-time intraocular pressure value that signal receiver obtains deducts the actual intraocular pressure value that tonometry value corresponding to datum mark is patient.
In 24 hours of actual testing process, detection head 1 can be controlled by flexible PCB 3 and submit one-time detection value to, each duration 1 second in every 5 minutes.All data all input store are preserved, and preserve the time of each data receiver.Intraocular pressure value representated by each detected value is obtained by experiment, and this experimental data input computer, entered signal processing by computer and calculate intraocular pressure value detected by different times.
S6, to signal receiver receive signal store, computer the data in memorizer are exported to printer carry out omnidistance intraocular pressure wave pattern print display.
The present invention is not only confined to above-mentioned concrete embodiment; persons skilled in the art are content disclosed in example and accompanying drawing; other multiple detailed description of the invention can be adopted to implement the present invention; therefore; every employing mentality of designing of the present invention and project organization; do the design that some simply change or change, all fall into the scope of protection of the invention.

Claims (7)

1. based on an intraocular pressure real-time measurement apparatus for conjunctival sac pressure detecting, it is characterized in that: comprise the detection head and signal receiver that load patients conjunctival's capsule;
Described detection head comprises air bag and the baroceptor be located in air bag and flexible PCB, and the air pressure in described air bag is normal atmosphere, and air bag contacts with eyeball, and is in pressured state; Described flexible PCB sends for responding to described air bag internal gas pressure and air pressure being converted to the signal of telecommunication;
Signal receiver, for receiving the signal that described flexible PCB sends.
2. according to claim 1 based on the intraocular pressure real-time measurement apparatus of conjunctival sac pressure detecting, it is characterized in that: the two ends of described air bag are respectively equipped with carves type connector, connect two carve type connector after, described balloon occlusion, and described flexible PCB switches on power.
3. according to claim 1 or 2 based on the intraocular pressure real-time measurement apparatus of conjunctival sac pressure detecting, it is characterized in that described flexible PCB comprises:
Pressure transducer, for detecting the intraocular pressure value of air bag induction; And
Processor, is converted to the signal of telecommunication for the intraocular pressure value detected by described pressure transducer;
Signal projector, for outwards launching the described signal of telecommunication.
4., according to claim 3 based on the intraocular pressure real-time measurement apparatus of conjunctival sac pressure detecting, characterized by further comprising:
Memorizer, for receive and store described signal projector launch signal.
5., according to claim 4 based on the intraocular pressure real-time measurement apparatus of conjunctival sac pressure detecting, characterized by further comprising:
Printer, is connected with described memorizer, for the data in print memory.
6. measured a method for intraocular pressure by device described in claim 1 in real time, it is characterized in that:
Detection head is loaded measured's conjunctival sac, air bag is contacted with eyeball, and air bag is in pressured state;
With the current intraocular pressure of tonometer test measured, obtain the current intraocular pressure value of measured, this test value is intraocular pressure reference value;
The atmospheric pressure value detected is converted to the signal of telecommunication and sends by the flexible PCB be located in air bag;
Signal receiver receives the signal of telecommunication that flexible PCB sends, and obtains intraocular pressure value according to the signal of telecommunication, corrects, thus obtain real-time intraocular pressure value according to reference value to this intraocular pressure value.
7. measure the method for intraocular pressure according to claim 6 in real time, it is characterized in that:
The omnidistance intraocular pressure wave pattern stored in memorizer is printed display by printer.
CN201510260814.3A 2015-05-21 2015-05-21 Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting and method Active CN104983395B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108670193A (en) * 2018-07-02 2018-10-19 苏州兆乘四海通科技有限公司 A kind of intraocular pressure tracking measurement instrument
CN111166490A (en) * 2020-02-25 2020-05-19 姜通渊 Medical robot pressure detection method and medical robot
CN111361473A (en) * 2018-12-26 2020-07-03 北京奇虎科技有限公司 Safety prompt system and child safety seat
CN111381693A (en) * 2018-12-29 2020-07-07 广州幻境科技有限公司 Intelligent pressure sensing pen
CN112539868A (en) * 2019-09-23 2021-03-23 北京远见医疗技术发展有限责任公司 Method and equipment for detecting internal pressure and surface tangent tension of spherical capsule through surface

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CN104523223A (en) * 2014-12-23 2015-04-22 苏州联科盛世科技有限公司 Portable intraocular pressure detector and intraocular pressure detection method

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US3929124A (en) * 1974-05-01 1975-12-30 Us Navy Opthalmodynamometer
US4089329A (en) * 1976-03-18 1978-05-16 University Of Utah Research Institute Noninvasive, continuous intraocular pressure monitor
US4305399A (en) * 1978-10-31 1981-12-15 The University Of Western Australia Miniature transducer
US20110015512A1 (en) * 2008-03-06 2011-01-20 The Regents Of The University Of California Measuring outflow resistance/facility of an eye
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108670193A (en) * 2018-07-02 2018-10-19 苏州兆乘四海通科技有限公司 A kind of intraocular pressure tracking measurement instrument
CN111361473A (en) * 2018-12-26 2020-07-03 北京奇虎科技有限公司 Safety prompt system and child safety seat
CN111381693A (en) * 2018-12-29 2020-07-07 广州幻境科技有限公司 Intelligent pressure sensing pen
CN112539868A (en) * 2019-09-23 2021-03-23 北京远见医疗技术发展有限责任公司 Method and equipment for detecting internal pressure and surface tangent tension of spherical capsule through surface
CN112539868B (en) * 2019-09-23 2022-03-11 北京远见医疗技术发展有限责任公司 Method and equipment for detecting internal pressure and surface tangent tension of spherical capsule through surface
CN111166490A (en) * 2020-02-25 2020-05-19 姜通渊 Medical robot pressure detection method and medical robot

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