CN105572017A - Smart gain adjustment system and blood cell analyzer - Google Patents
Smart gain adjustment system and blood cell analyzer Download PDFInfo
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- CN105572017A CN105572017A CN201510962811.4A CN201510962811A CN105572017A CN 105572017 A CN105572017 A CN 105572017A CN 201510962811 A CN201510962811 A CN 201510962811A CN 105572017 A CN105572017 A CN 105572017A
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- digital potentiometer
- blood cell
- regulation resistance
- resistance
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
Abstract
The invention is applicable to the field of medical detection equipment, and provides a smart gain adjustment system and a blood cell analyzer. The adjustment system comprises an animal species selection interaction unit, a digital potentiometer parameter library storage unit and a digital potentiometer interface unit. The digital potentiometer interface unit comprises a digital potentiometer driving program, a digital potentiometer interface circuit and a programmable digital potentiometer. The digital potentiometer interface unit outputs digital potentiometer parameters corresponding to preset animal species to the programmable digital potentiometer. The smart gain adjustment system and the blood cell analyzer have the advantages that the programmable digital potentiometer is arranged in a blood cell volume analog signal conditioning circuit, and resistance parameters of the programmable digital potentiometer are set suitably according to preset parameters, so that the same model of blood cell analyzers are applicable to blood cell analysis of various types of animals, and adaptability of the blood cell analyzer is improved.
Description
Technical field
The invention belongs to medical treatment detection device field, particularly relate to a kind of Intelligent Gain regulating system and cellanalyzer.
Background technology
Along with pet enters daily life day by day; state, inside and outside pet clinic quantity present obvious growing trend in recent years; people are also more and more stronger to animal protection consciousness; so the cellanalyzer for animal has also spread to pet clinic, zoo, herding Zhan Deng Animal Medicine mechanism gradually.
At present, during based on the animal blood cytoanalyze of electrical impedance method to blood count, in blood sample, blood cell volume is larger, the impedance that haemocyte is formed by cellanalyzer sensor is also larger, because be discrete by the haemocyte in the blood sample after diluting, so haemocyte is pulsation by the impedance variation caused during sensor.The impedance variation of sensor is converted to the electric impulse signal of certain amplitude by current cellanalyzer by blood cell volume analog signal conditioner circuit, in order to the amplitude of variation of this electric pulse is limited in certain scope so that subsequent conditioning circuit process, gain adjusting circuit is devised in above-mentioned analog signal conditioner circuit, adjustable electronic devices and components are wherein mechanical type potentiometer, this potentiometer is set by hand before instrument dispatches from the factory, and the gain of the blood cell volume analog signal conditioner circuit after therefore current cellanalyzer dispatches from the factory is fixed.
Because the gain of blood cell volume analog signal conditioner circuit is fixed, simultaneously due to dissimilar animal (as common cat and dog) haemocyte (comprising leucocyte, red blood cell and blood platelet) between form, volume difference larger, so, the animal blood cytoanalyze of same model can not be applicable to the blood cell analysis of polytype animal effectively on the market at present, such as, accurately when measuring the haemocyte of cat, and the haemocyte measuring dog may be just inaccurate, vice versa.
Therefore, existing animal blood cytoanalyze is fixed due to the gain of blood cell volume analog signal conditioner circuit, in type of animal adaptability, there is limitation, the haemocyte of the cellanalyzer of same model to many animals can not be used effectively to analyze.
Summary of the invention
The embodiment of the present invention provides a kind of Intelligent Gain regulating system, being intended to solve existing animal blood cytoanalyze due to the gain of blood cell volume analog signal conditioner circuit is fixed, in type of animal adaptability, there is limitation, the cellanalyzer of same model can not be used the haemocyte of many animals to be carried out to the problem effectively analyzed.
The embodiment of the present invention is achieved in that a kind of Intelligent Gain regulating system,
Comprise animal species and select interactive unit, the digital regulation resistance parameter library storage unit selecting interactive unit to be connected with described animal species and the digital regulation resistance interface unit be connected with described animal species selection unit;
Described animal species selects interactive unit comprise control chip, the keyboard be connected with described control chip or touch-screen and be connected display with described control chip, for pre-setting detected animal species;
The digital regulation resistance parameter that at least one animal that described digital regulation resistance parameter library storage unit comprises storage medium and storage thereof is corresponding;
Described digital regulation resistance interface unit comprise based on described control chip digital regulation resistance driver, with the digital regulation resistance interface circuit of described digital regulation resistance driver compatibility and the programmable digital potentiometer that is connected with described digital regulation resistance interface circuit, described programmable digital potentiometer connects blood cell volume analog signal conditioner circuit, and described digital regulation resistance interface unit exports digital regulation resistance parameter corresponding for the described animal species pre-set to described programmable digital potentiometer.
Further, described programmable digital potentiometer (U1) comprises clock signal input terminal (SCL), data signal input (SDA), input end (A), output terminal (B), tap terminals (W), power end (VDD) and independent current source end (VLOGIC);
Described clock signal input terminal (SCL) connects the clock signal output terminal (I2CSCL) of described digital appliances interface circuit, described data signal input (SDA) connects the data signal output (I2CSDA) of described digital appliances interface circuit, described input end (A) connects one end of the first voltage stabilizing diode (D1) and the first resistance (R1), described output terminal (B) and tap terminals (W) ground connection, described power end (VDD) and independent current source end (VLOGIC) connect power input (VCC);
The other end ground connection of described first voltage stabilizing diode (D1), the reverse input end of the other end concatenation operation amplifier (U2A) of described first resistance (R1) and one end of the second resistance (R2), the other end of described second resistance (R2) connects the output terminal of described operational amplifier (U2A), the output terminal of described operational amplifier (U2A) connects the input end of the late-class circuit of described blood cell volume analog signal conditioner circuit, the front stage circuits output terminal of described blood cell volume analog signal conditioner circuit connects one end of the 3rd resistance (R3), the other end of described 3rd resistance (R3) connects the input end in the same way of described operational amplifier.
Further, the clock signal output terminal (I2CSCL) of the clock signal input terminal (SCL) of described programmable digital potentiometer, data signal input (SDA) and described digital appliances interface circuit, data signal output (I2CSDA) are connected by I2C bus.
Further, the clock signal output terminal (I2CSCL) of the clock signal input terminal (SCL) of described programmable digital potentiometer, data signal input (SDA) and described digital appliances interface circuit, data signal output (I2CSDA) are connected by a kind of bus in SPI/1-WIRE/UART bus.
Further, the resistance of described programmable digital potentiometer arranges scope is 0 ~ 10K Ω.
Further, the power end (VDD) of described programmable digital potentiometer connects the direct supply that voltage is 5V.
Further, described storage medium is data security storage card.
The embodiment of the present invention also provides a kind of cellanalyzer, and wherein, described cellanalyzer comprises above-mentioned Intelligent Gain regulating system.
The Intelligent Gain regulating system of the embodiment of the present invention, by arranging programmable digital regulation resistance in blood cell volume analog signal conditioner circuit, the setting that the resistance parameter of parameter to programmable digital potentiometer in the digital regulation resistance parameter library that use pre-sets adapts, make the type of animal that the cellanalyzer of same model is selected according to user, the gain of real-time change blood cell volume analog signal conditioner circuit, to be applicable to the blood cell analysis of polytype animal, improve the adaptability of cellanalyzer.
Accompanying drawing explanation
Fig. 1 is the module composition schematic diagram of the Intelligent Gain regulating system that the embodiment of the present invention provides;
Fig. 2 is the module composition schematic diagram of the Intelligent Gain regulating system that the embodiment of the present invention two provides;
Fig. 3 is the programmable digital potentiometer circuit schematic diagram of the Intelligent Gain regulating system that the embodiment of the present invention provides.
Embodiment
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
As shown in Figure 1, a kind of Intelligent Gain regulating system that the embodiment of the present invention provides,
Comprise animal species and select interactive unit 1, the digital regulation resistance parameter library storage unit 2 selecting interactive unit 1 to be connected with described animal species, and the digital regulation resistance interface unit 3 to be connected with described animal species selection unit 1, described animal species selects interactive unit to be belong to which kind of animal to carry out artificial selection to the animal be detected before carrying out the haemocyte of animal analyzing, digital regulation resistance parameter library storage unit is for resistance parameter value corresponding to the yield value that prestores blood cell volume analog signal conditioner circuit corresponding to often kind of animal, ensure the accuracy detected, digital regulation resistance interface unit exports resistance parameter value corresponding with the animal species that user selects in digital regulation resistance parameter library storage unit to digital regulation resistance, make the type of animal that the cellanalyzer of same model can be selected according to user, the gain of real-time change blood cell volume analog signal conditioner circuit, be applicable to the blood cell analysis of polytype animal, no longer be confined to the blood cell analysis of single animal species, the haemocyte avoiding existing Blood cell analyzer detection two kinds of animals needs the cellanalyzer of two types, or use the phenomenon causing testing result mistake during the haemocyte of the Blood cell analyzer detection different animals of same model, improve the adaptability of cellanalyzer, ensure that the accuracy of the Blood cell analyzer detection many animals haemocyte using same model, also improve the detection efficiency of many animals haemocyte simultaneously,
Shown in figure 2, described animal species selects interactive unit to comprise control chip 11, the keyboard be connected with described control chip 11 or touch-screen 12 and display 13, for pre-setting detected animal species, in embodiments of the present invention, control chip can adopt ARM series CPU, also single-chip microcomputer can be adopted to control, with the control software design in addition of control chip Hardware match, described control software design and described digital regulation resistance driver both can be stored in the embedded storage medium of described control chip, also can be stored in the storage medium independent of described control chip, keyboard or touch-screen and display are used for the selection of type of animal,
Digital regulation resistance parameter corresponding at least one animal that described digital regulation resistance parameter library storage unit 2 comprises storage medium 21 and stores, in embodiments of the present invention, storage medium both can be embedded in described control chip, also can independent of described control chip, can be data security storage card (SD card), or USB flash disk, disks etc. have the medium storing data function, the digital regulation resistance parameter that at least one animal is corresponding is stored in storage medium, such as, the corresponding a kind of digital regulation resistance parameter values of dog, the corresponding another kind of digital regulation resistance parameter values of cat, in embodiments of the present invention, digital regulation resistance parameter values scope is 0 ~ 255, multiple different animal is made to use the different digital potentiometer parameter value pre-set when detecting, described digital regulation resistance parameter value verifies the adaptability of this digital regulation resistance setting value by a certain amount of clinical testing data,
Described digital regulation resistance interface unit 3 comprises the digital regulation resistance driver 31 based on described control chip 11, with the digital regulation resistance interface circuit 32 of described digital regulation resistance driver 31 compatibility, and the programmable digital potentiometer 33 to be connected with described digital regulation resistance interface circuit 32, described programmable digital potentiometer 33 connects blood cell volume analog signal conditioner circuit 4, described digital regulation resistance interface unit 3 exports digital regulation resistance parameter corresponding for the described animal species pre-set to described programmable digital potentiometer 33, the optimum configurations of programmable digital potentiometer is that parameter value is sent to programmable digital potentiometer by digital regulation resistance driver through the mode of universal serial bus by control chip, to realize the adjustment of the different gains of blood cell volume analog signal conditioner circuit, to adapt to the detection of different animals type haemocyte.
Concrete, as shown in Figure 3, in embodiments of the present invention, described programmable digital potentiometer (U1) comprises clock signal input terminal (SCL), data signal input (SDA), input end (A), output terminal (B), tap terminals (W), power end (VDD) and independent current source end (VLOGIC);
Described clock signal input terminal (SCL) connects the clock signal output terminal (I2CSCL) of described digital appliances interface circuit, described data signal input (SDA) connects the data signal output (I2CSDA) of described digital appliances interface circuit, described input end (A) connects one end of the first voltage stabilizing diode (D1) and the first resistance (R1), described output terminal (B) and tap terminals (W) ground connection, described power end (VDD) and independent current source end (VLOGIC) connect power input (VCC), data signal input (SDA) receives the digital regulation resistance parameter electric signal that control chip transmits, , and the intelligence realizing resistance value between input end (A) and output terminal (B) changes,
The other end ground connection of described first voltage stabilizing diode (D1), first voltage stabilizing diode (D1) plays the effect of protection circuit, the reverse input end of the other end concatenation operation amplifier (U2A) of described first resistance (R1) and one end of the second resistance (R2), the other end of described second resistance (R2) connects the output terminal of described operational amplifier (U2A), the output terminal of described operational amplifier (U2A) connects the input end of the late-class circuit 42 of described blood cell volume analog signal conditioner circuit, front stage circuits 41 output terminal of described blood cell volume analog signal conditioner circuit connects one end of the 3rd resistance (R3), the other end of described 3rd resistance (R3) connects the input end in the same way of described operational amplifier, operational amplifier (U2A) realizes the amplification of measuring-signal in blood cell volume analog signal conditioner circuit, be convenient to the use of late-class circuit.
As one embodiment of the present of invention, clock signal output terminal (I2CSCL), the data signal output (I2CSDA) of the clock signal input terminal (SCL) of described programmable digital potentiometer, data signal input (SDA) and described digital appliances interface circuit are connected by I2C bus, I2C bus adopts two-wire system serial transmission mode, make digital regulation resistance interface circuit structure simply effective, take up room little, reduce cost, meet again the requirement of multiple digital regulation resistance transformation parameter in bus simultaneously.
As an alternative embodiment of the invention, clock signal output terminal (I2CSCL), the data signal output (I2CSDA) of the clock signal input terminal (SCL) of described programmable digital potentiometer, data signal input (SDA) and described digital appliances interface circuit are connected by a kind of bus in SPI/1-WIRE/UART bus, multiple transfer bus makes cellanalyzer adapt to the transmission requirement of different pieces of information, improves the adaptability of equipment.
In embodiments of the present invention, it is 0 ~ 10K Ω that the resistance of described programmable digital potentiometer arranges scope, Standard resistance range adapts to the different gains value of blood cell volume analog signal conditioner circuit corresponding to different animal species, and the analysis carrying out different animals haemocyte detects.
In embodiments of the present invention, the power end (VDD) of described programmable digital potentiometer connects the direct supply that voltage is 5V, and 5V direct supply ensures the confession electrical stability of programmable digital potentiometer, and ensures the accuracy that blood cell analysis is measured.
Also provide a kind of cellanalyzer in the embodiment of the present invention, wherein, described cellanalyzer comprises Intelligent Gain regulating system described above, makes animal blood cytoanalyze be applicable to many animals blood testing, improves the practicality of equipment.
The Intelligent Gain regulating system that the embodiment of the present invention provides and cellanalyzer, by arranging programmable digital regulation resistance in blood cell volume analog signal conditioner circuit, make the setting that the resistance parameter of parameter to programmable digital potentiometer in the digital regulation resistance parameter library that pre-sets adapts, make the type of animal that the cellanalyzer of same model is selected according to user, the gain of real-time change blood cell volume analog signal conditioner circuit, to be applicable to the blood cell analysis of polytype animal, ensure the accuracy detected, improve the adaptability of cellanalyzer and the efficiency of detection.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (8)
1. an Intelligent Gain regulating system, it is characterized in that, comprise animal species and select interactive unit, the digital regulation resistance parameter library storage unit selecting interactive unit to be connected with described animal species and the digital regulation resistance interface unit be connected with described animal species selection unit;
The display that described animal species selects interactive unit to comprise control chip, the keyboard be connected with described control chip or touch-screen and be connected with described control chip, for pre-setting detected animal species;
The digital regulation resistance parameter that at least one animal that described digital regulation resistance parameter library storage unit comprises storage medium and storage thereof is corresponding;
Described digital regulation resistance interface unit comprise based on described control chip digital regulation resistance driver, with the digital regulation resistance interface circuit of described digital regulation resistance driver compatibility and the programmable digital potentiometer that is connected with described digital regulation resistance interface circuit, described programmable digital potentiometer connects blood cell volume analog signal conditioner circuit, and described digital regulation resistance interface unit exports digital regulation resistance parameter corresponding for the described animal species pre-set to described programmable digital potentiometer.
2. Intelligent Gain regulating system according to claim 1, it is characterized in that, described programmable digital potentiometer (U1) comprises clock signal input terminal (SCL), data signal input (SDA), input end (A), output terminal (B), tap terminals (W), power end (VDD) and independent current source end (VLOGIC);
Described clock signal input terminal (SCL) connects the clock signal output terminal (I2CSCL) of described digital appliances interface circuit, described data signal input (SDA) connects the data signal output (I2CSDA) of described digital appliances interface circuit, described input end (A) connects one end of the first voltage stabilizing diode (D1) and the first resistance (R1), described output terminal (B) and tap terminals (W) ground connection, described power end (VDD) and independent current source end (VLOGIC) connect power input (VCC);
The other end ground connection of described first voltage stabilizing diode (D1), the reverse input end of the other end concatenation operation amplifier (U2A) of described first resistance (R1) and one end of the second resistance (R2), the other end of described second resistance (R2) connects the output terminal of described operational amplifier (U2A), the output terminal of described operational amplifier (U2A) connects the input end of the late-class circuit of described blood cell volume analog signal conditioner circuit, the front stage circuits output terminal of described blood cell volume analog signal conditioner circuit connects one end of the 3rd resistance (R3), the other end of described 3rd resistance (R3) connects the input end in the same way of described operational amplifier.
3. Intelligent Gain regulating system according to claim 2, it is characterized in that, clock signal output terminal (I2CSCL), the data signal output (I2CSDA) of the clock signal input terminal (SCL) of described programmable digital potentiometer, data signal input (SDA) and described digital appliances interface circuit are connected by I2C bus.
4. Intelligent Gain regulating system according to claim 2, it is characterized in that, clock signal output terminal (I2CSCL), the data signal output (I2CSDA) of the clock signal input terminal (SCL) of described programmable digital potentiometer, data signal input (SDA) and described digital appliances interface circuit are connected by a kind of bus in SPI/1-WIRE/UART bus.
5. the Intelligent Gain regulating system according to claim 3 or 4, is characterized in that, it is 0 ~ 10K Ω that the resistance of described programmable digital potentiometer arranges scope.
6. Intelligent Gain regulating system according to claim 5, is characterized in that, the power end (VDD) of described programmable digital potentiometer connects the direct supply that voltage is 5V.
7. Intelligent Gain regulating system according to claim 3, is characterized in that, described storage medium is data security storage card.
8. a cellanalyzer, is characterized in that, described cellanalyzer comprises the Intelligent Gain regulating system as described in any one of claim 1 to 7.
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| CN201510962811.4A CN105572017B (en) | 2015-12-21 | 2015-12-21 | A kind of Intelligent Gain regulating system and cellanalyzer |
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| CN201510962811.4A CN105572017B (en) | 2015-12-21 | 2015-12-21 | A kind of Intelligent Gain regulating system and cellanalyzer |
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