CN106073939A - The tissue repairing's sheet used under peritoneoscope - Google Patents

The tissue repairing's sheet used under peritoneoscope Download PDF

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Publication number
CN106073939A
CN106073939A CN201610505032.6A CN201610505032A CN106073939A CN 106073939 A CN106073939 A CN 106073939A CN 201610505032 A CN201610505032 A CN 201610505032A CN 106073939 A CN106073939 A CN 106073939A
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China
Prior art keywords
tissue repairing
sheet
peritoneoscope
used under
district
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CN201610505032.6A
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CN106073939B (en
Inventor
申英末
陈杰
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Tianjin Baihe Zhiyuan Medical Technology Co.,Ltd.
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申英末
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Priority to CN201610505032.6A priority Critical patent/CN106073939B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063Implantable repair or support meshes, e.g. hernia meshes

Abstract

The present invention relates to the tissue repairing's sheet used under a kind of peritoneoscope, belong to the technical field of medical disposable material.The tissue repairing's sheet used under the peritoneoscope of the present invention, has marginal area and the interior zone limited by described marginal area, and the sealing strip of described marginal area is on same datum plane, and described interior zone is caved inward by described datum plane and forms curved surface;Described datum plane is 12 °~16 ° with the angle of described curved surface, and described datum plane is 15~22mm with the ultimate range of described curved surface.Tissue repairing's sheet of the present invention is suitable for the anatomical features of inguinal region, laminating intact with iliac vessels, can use under peritoneoscope, and there is good compliance, location easily, stitching or the stitching that can reduce patch are fixed, thus narcotic consumption alleviate the misery of patient when can also reduce operation.

Description

The tissue repairing's sheet used under peritoneoscope
Technical field
The present invention relates to the technical field of medical disposable material, it is more particularly related to use under a kind of peritoneoscope Tissue repairing's sheet.
Background technology
Inguinal hernia is surgical common disease and frequently-occurring disease, and the treatment maximally effective treatment means of adult inguinal hernia is hands at present Art is treated.Including traditional operation and the Tension-free Hernioplasty of use sticking patch, the cure mechanism of Hammock Method operation is exactly Use artificial material that weak transverse fascia is repaired or substituted, have become as the main flow for the treatment of adult inguinal hernia at present Modus operandi, laparoscopic repair for groin repairing operation is an important component part of Hammock Method operation.Peritoneoscope abdomen stock Ditch herniorrhaphy be the development with laparoscopic technique and gradually by a kind of newer hernia that surgeon accepted and used Gas treatment operation, is a kind of posterior approach art formula, perform the operation by laparoscopic technique from posterior approach to human body pectineus porose area peritoneum and Hernia defect carries out dissecting and dissociating, and uses planar patch to substitute defective region transverse fascia, sufficiently large in use in theory Patch treatment after, laparoscopic hernia repair can prevent and treat combination, reach effect a radical cure inguinal hernia effect.
In the prior art, the various sticking patch used based on polypropylene material, the peritoneoscope abdomen stock of current preforming The special sticking patch of ditch herniorrhaphy is respectively arranged with pluses and minuses, and traditional plane hernia structure not only operates complexity, and is difficult to accurately determine Position, when operation, anesthesia duration is the longest.
Summary of the invention
In order to solve above-mentioned technical problem of the prior art, it is an object of the invention to provide and use under a kind of peritoneoscope Tissue repairing's sheet.
In order to realize foregoing invention purpose, present invention employs techniques below scheme:
Under a kind of peritoneoscope use tissue repairing's sheet, it is characterised in that: described tissue repairing sheet have marginal area and The interior zone limited by described marginal area, the sealing strip of described marginal area is on same datum plane, and described interior Region, portion is caved inward by described datum plane and forms curved surface;Described datum plane is 12 °~16 ° with the angle of described curved surface, Described datum plane is 15~22mm with the ultimate range of described curved surface.
Wherein, described curved surface by X to the L limit of left end and right-hand member longest distance and the W limit of Y-direction top and bottom longest distance Definition, described X is outwardly directed A district to left end, and described X is the B district being connected with inguinal ligament to right-hand member, under described Y-direction End is provided with the groove T region of iliac vessels traveling, and extends out M district with the convex side of described groove T region adjacent.
Wherein, a length of the 12~a length of the 8 of 18cm, W limit~12cm of described L limit.
Wherein, a length of the 2.5~4.0cm of groove width W1 in described groove T region, depth bounds is 1.0~1.5cm, long Degree scope is 2~3cm, and groove center distance X is 5~8cm to right-hand member distance L1.
Wherein, length L2 in M district is 5~8cm, and width W2 is 4~6cm.
Wherein, described tissue repairing sheet is formed by polypropylene or braided polyester.
Wherein, tissue repairing's sheet surface-coated in described M district has bio-matrix coating.
Compared with prior art, the tissue repairing's sheet used under peritoneoscope of the present invention has the advantages that
Tissue repairing's sheet of the present invention is suitable for the anatomical features of inguinal region, and laminating intact with iliac vessels can be at peritoneoscope Lower use, and there is good compliance, location easily, it is possible to reduce stitching or the stitching of patch are fixed, thus can also Narcotic consumption alleviate the misery of patient when reducing operation.
Accompanying drawing explanation
Fig. 1 is the scale diagrams of the tissue repairing's sheet used under the peritoneoscope of embodiment 1.
Fig. 2 is the left view of the tissue repairing's sheet used under the peritoneoscope of embodiment 1.
Detailed description of the invention
Below with reference to specific embodiment, the tissue repairing's sheet used under peritoneoscope of the present invention is done further Illustrate, to help those skilled in the art that inventive concept, the technical scheme of the present invention are had more complete, accurate and deep reason Solve.
Embodiment 1
As shown in Figure 1-2, the tissue repairing's sheet used under the peritoneoscope of the present embodiment, there is marginal area and by described limit Edge region limit interior zone, the sealing strip of described marginal area is on same datum plane, and described interior zone by Described datum plane caves inward formation curved surface;Described datum plane and the angle of described curved surfaceIt is 12 °~16 °, described benchmark Plane is 15~22mm with the ultimate range of described curved surface.Described curved surface by X to the L limit of left end and right-hand member longest distance and Y-direction The W limit definition of top and bottom longest distance, described X is outwardly directed A district to left end, and described X to right-hand member is and groin The B district that ligament connects, described Y-direction lower end is provided with the groove T region of iliac vessels traveling, and with described groove T region adjacent Convex side extend out M district, walk line position at iliac vessels and groove T region be set, thus preferably can fit with blood vessel, it is possible to reduce mend Stitching or the stitching of sheet are fixed.A length of the 12 of described L limit~a length of the 8 of 18cm, W limit~12cm.Described groove T region A length of the 2.5 of groove width W1~4.0cm, depth bounds is 1.0~1.5cm, and length range is 2~3cm, groove center distance X It is 5~8cm to right-hand member distance L1.Length L2 in M district is 5~8cm, and width W2 is 4~6cm.Described tissue repairing sheet is by poly-third Alkene or braided polyester form, and use monfil braiding to form, and antibacterial can be avoided to grow thereon.
Tissue repairing's sheet surface-coated in described M district has acellular matrix coating, and polypropylene can be avoided iliac vessels, testis The direct friction such as ball arteriovenous, deferent duct stimulate, and biodegradable acellular matrix composition is that the extracellular matrix such as collagen, glycosaminoglycans becomes Point, biocompatibility is high, the degree of the reaction that can reduce inflammation.In the present embodiment, described acellular matrix refers to be taken off Cell is so that the tissue that removes from structural extracellular matrix of nucleus and cell component.Acellular matrix is by including organ Or the tissue preparation of the separate section of organ.Tissue include, but is not limited to cardiac valve, submucous layer of small intestine, corium, amniotic membrane, Bladder, nethike embrane, pericardium, ligament, blood vessel etc..Tissue is available from various mammal, such as goat, pig, cattle, sheep, Horse etc..De-cell step be usually directed to by extract with the saline solution containing detergent and with endonuclease digestion by the way of remove Cell component, is then transferred to acellular matrix in aqueous solution.In one embodiment, before being transferred in aqueous solution, Acellular matrix is processed into less fragment.Acellular matrix can be processed into less broken by such as following conventional method Block: cut with shears or blade;Clay into power with such as ball milling and cryogrinding;And jet grinding.By by de-cell base Matter is processed into less fragment (such as powder), can form bigger surface area, it is thus possible to be dissolved in quickly in aqueous solution.? In one embodiment, before adding in aqueous solution, by cryogrinding, acellular matrix is processed into powder.Can be used for implementing The aqueous solution of the present invention includes water, physiological buffer and saline.Physiological buffer includes, but is not limited to buffer saline (such as phosphorus Hydrochlorate buffer saline (PBS)), Hank balanced salt solution, Tris buffer saline and Hepes buffer saline.In one embodiment, Aqueous solution is water, and aqueous solution optionally comprises the plasticizer of enough effective doses.Plasticizer include, but is not limited to glycerol, the third two Alcohol, Polyethylene Glycol.In one embodiment, plasticizer is glycerol.Character ground as an example, acellular matrix glue (such as) passes through Prepared by following steps: provide the acellular matrix such as taking off Cuticle of cell substrate etc;Then will alternately through cryogrinding De-Cuticle of cell substrate is processed into powder, and this acellular matrix powder has the granularity of less than about 2mm;About 1.0g is taken off cell base Matter powder is mixed in 10ml aqueous solution (such as water or phosphate buffered saline (PBS) (PBS)), to form acellular matrix mixture. Generally, the content of acellular matrix is calculated as about 2 weight % to about 30 weight % by the weight of aqueous solution, it is therefore preferable to about 5 weights Amount % to about 20 weight %.In another embodiment, the content of acellular matrix is calculated as about 10 weights by the weight of aqueous solution Amount %.Then by acellular matrix mixture incubation enough effective time at enough effective temperature, generally at about 70 DEG C Incubation about 10 minutes to about 48 hours at about 100 DEG C, preferably from about 80 DEG C to about 90 DEG C, and generally incubation about 1 hour is extremely About 5 hours.Higher temperature can also be used at a higher pressure, such as, under 2 atmospheric pressure, use the temperature of 120 DEG C. Acellular matrix glue allow to be cooled to about 37 DEG C for using immediately, or be cooled to room temperature or following, until preparing to use Temperature.As preferably, described biodegradable acellular matrix coating is the coating containing glycosaminoglycans, as the most also containing There is carboxymethyl chitosan (addition is the 10~50% of glycosaminoglycans weight);It is possible not only to reduce inflammation by the two compounding use The degree of reaction, and controlled trial (uncoated patch, and only coating is containing glycosaminoglycans) show that it can reduce hands The probability (about reducing by 5~15%, sample number n=120) of postoperative recurrence and infection notices that sub-thread not Absorption Line extends only through when sewing up Propene polymer patch layer, does not penetrate biological sticking patch layer, and sewing up the sticking patch after having fixed should be open and flat without curling, no-station pole canopy, operation Wound surface carefully to stop blooding, to ensure the success of operative repair.
For the ordinary skill in the art, the present invention is simply exemplarily described by specific embodiment, Obviously the present invention implements and is not subject to the restrictions described above, as long as the method design that have employed the present invention is entered with technical scheme The improvement of various unsubstantialities of row, or the most improved design by the present invention and technical scheme directly apply to other occasion , all within protection scope of the present invention.

Claims (10)

1. under a peritoneoscope use tissue repairing's sheet, it is characterised in that: described tissue repairing sheet have marginal area and by The interior zone that described marginal area limits, the sealing strip of described marginal area is on same datum plane, and described inside Region is caved inward by described datum plane and forms curved surface;Described datum plane is 12 °~16 ° with the angle of described curved surface, institute The ultimate range stating datum plane and described curved surface is 15~22mm.
The tissue repairing's sheet used under peritoneoscope the most according to claim 1, it is characterised in that: described curved surface is by X to the left End defines with the L limit of right-hand member longest distance and the W limit of Y-direction top and bottom longest distance, and described X is outwardly directed to left end A district, described X is the B district being connected with inguinal ligament to right-hand member, and described Y-direction lower end is provided with the groove T district of iliac vessels traveling Territory, and extend out M district with the convex side of described groove T region adjacent.
The tissue repairing's sheet used under peritoneoscope the most according to claim 2, it is characterised in that: described L limit a length of A length of the 8~12cm of 12~18cm, W limit.
The tissue repairing's sheet used under peritoneoscope the most according to claim 2, it is characterised in that: described groove T region A length of the 2.5 of groove width W1~4.0cm, depth bounds is 1.0~1.5cm, and length range is 2~3cm, groove center distance X It is 5~8cm to right-hand member distance L1.
Under peritoneoscope the most according to claim 2 use tissue repairing's sheet, it is characterised in that: length L2 in M district be 5~ 8cm, width W2 are 4~6cm.
Under peritoneoscope the most according to claim 1 use tissue repairing's sheet, it is characterised in that: described tissue repairing sheet by Polypropylene or braided polyester form.
Under peritoneoscope the most according to claim 6 use tissue repairing's sheet, it is characterised in that: described tissue repairing sheet by Monfil braiding forms.
The tissue repairing's sheet used under peritoneoscope the most according to claim 1, it is characterised in that: the tissue in described M district is repaiied Patch faces is coated with biodegradable acellular matrix coating.
The tissue repairing's sheet used under peritoneoscope the most according to claim 8, it is characterised in that: described de-cell biological base Matter coating is the coating containing glycosaminoglycans.
The tissue repairing's sheet used under peritoneoscope the most according to claim 9, it is characterised in that: described de-cell biological Matrix coating is possibly together with carboxymethyl chitosan.
CN201610505032.6A 2016-06-30 2016-06-30 The tissue repairing's piece used under laparoscope Active CN106073939B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288867A (en) * 2018-10-26 2019-02-01 上海慧存医疗科技有限公司 A kind of preparation method of compound amnion powder preparation
CN114795573A (en) * 2021-01-27 2022-07-29 应脉医疗科技(上海)有限公司 3D inguinal area hernia repair patch

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007666A1 (en) * 1993-09-13 1995-03-23 C.R. Bard, Inc. Curved prosthetic mesh and method of manufacture
US5972007A (en) * 1997-10-31 1999-10-26 Ethicon Endo-Surgery, Inc. Energy-base method applied to prosthetics for repairing tissue defects
US6174320B1 (en) * 1994-09-29 2001-01-16 Bard Asdi Inc. Hernia mesh patch with slit
CN101112335A (en) * 2006-07-28 2008-01-30 北京天助畅运医疗技术有限公司 Embeddable multipurpose external hernia remedying slice
CN102379729A (en) * 2010-09-03 2012-03-21 北京天助畅运医疗技术股份有限公司 Laparoscopic hernia repair mesh
CN104039267A (en) * 2011-12-29 2014-09-10 索弗拉狄姆产品公司 Prosthesis for inguinal hernia
CN204501104U (en) * 2015-03-30 2015-07-29 广西壮族自治区人民医院 A kind of sticking patch of repairing male inguinal hernia of laparoscopic surgery
CN206063259U (en) * 2016-06-30 2017-04-05 申英末 The tissue repairing's piece used under peritoneoscope

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007666A1 (en) * 1993-09-13 1995-03-23 C.R. Bard, Inc. Curved prosthetic mesh and method of manufacture
US6174320B1 (en) * 1994-09-29 2001-01-16 Bard Asdi Inc. Hernia mesh patch with slit
US5972007A (en) * 1997-10-31 1999-10-26 Ethicon Endo-Surgery, Inc. Energy-base method applied to prosthetics for repairing tissue defects
CN101112335A (en) * 2006-07-28 2008-01-30 北京天助畅运医疗技术有限公司 Embeddable multipurpose external hernia remedying slice
CN102379729A (en) * 2010-09-03 2012-03-21 北京天助畅运医疗技术股份有限公司 Laparoscopic hernia repair mesh
CN104039267A (en) * 2011-12-29 2014-09-10 索弗拉狄姆产品公司 Prosthesis for inguinal hernia
CN204501104U (en) * 2015-03-30 2015-07-29 广西壮族自治区人民医院 A kind of sticking patch of repairing male inguinal hernia of laparoscopic surgery
CN206063259U (en) * 2016-06-30 2017-04-05 申英末 The tissue repairing's piece used under peritoneoscope

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288867A (en) * 2018-10-26 2019-02-01 上海慧存医疗科技有限公司 A kind of preparation method of compound amnion powder preparation
CN114795573A (en) * 2021-01-27 2022-07-29 应脉医疗科技(上海)有限公司 3D inguinal area hernia repair patch
CN114795573B (en) * 2021-01-27 2024-03-19 心宜医疗器械(深圳)有限公司 3D inguinal region hernia repair patch

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