CN2621723Y - Non-invasive percutaneous electrical stimulator for treating obstructive sleep apnea syndrome - Google Patents

Abstract

The utility model relates to a non-invasive percutaneous electrical stimulator for treating obstructive sleep apnea syndrome, consisting of a plurality of non-implanted percutaneous electrodes, an apnea sensor and an electrical stimulation pulse series generator; the electrical stimulation pulse series generator includes a programmable pulse control system consisting of a programmable micro-processing unit (10), a program memory ROM module (12) and a data memory RAM module (11), and a electrical stimulation pulse series generating circuit (22). In the treating process, the patient will not feel uncomfortable; the device is of no noise, the low cost, safety and effectiveness, and convenient use. When the device is used, no medical staff is needed to be on duty; and even the patient can use the device at home.

Description

The noinvasive transcutaneous electrostimulation device of treatment obstructive sleep apnea syndrome

Technical field: this utility model relates to a kind of noinvasive transcutaneous electrostimulation device for the treatment of obstructive sleep apnea syndrome.

Background technology: present known sleep illness is 84 kinds, and its sleep apnea syndrome accounts for 60-70%, and blocking sleep apnea syndrome in the population of China, to send out sickness rate be 3%, and rate 13% is levied in snore.This type of patient since when sleep air flue subside repeatedly and cause that asphyxia shows effect repeatedly, cause the nighttime sleep hypoxia to cause serious Sleep architecture disorder, thereby cause that often excessive daytime is drowsiness, absent minded, vigilance descends, bradykinesia, and these are the major reasons that cause vehicle accident.This type of disease can cause the multisystem dysfunction, be pulmonary heart disease, the heart, brain, kidney, angiopathy, can concurrent erythrocytosis, secondary hypertension, pulmonary heart disease, congestive heart failure and sleep period arrhythmia, one of the higher and endocrine of viscosity of blood, the handicapped major reason of fat growth hormone metabolism, potential deadly possibility is arranged, very big to health hazard.

And less to the Therapeutic Method of Obstructive Sleep Apnea (OSAS) at present, take operative treatment and non-operation expectant treatment usually.Surpass 45 years old because the OSAS patient's age is most of, operative treatment has certain risk and untoward reaction, and most patients are easier to accept non-operative treatment.Operative treatment is one of main Therapeutic Method of Obstructive Sleep Apnea, wherein with Uvulopalatopharyngoplasty (uvulopal-atopharyngoplasty, UPPP) being most widely used, only is about 50% but add up effective percentage more than 6 months according to lot of documents report UPPP postoperative.Keeping positive airway pressure (CPAP) treatment and can obviously reduce the asphyxia number of times and improve symptom and non-operative treatment mostly adopts, is effective method comparatively at present.But because of all putting on breathing mask every night, the noise that not only some patient's incompatibility, and respirator is sent can influence patient and household's sleep, and its medical expense is not low yet in addition, so cause the treatment of continuous positive pressure venti lation (CPAP) to be difficult for promoting.

After testing, determine, after sleep state generation asphyxia, give suitably electricity irritation genioglossus is shunk, the tongue body reach, pharyngeal cavity enlarges relatively, has prevented to weigh down behind the root of the tongue that the obstruction that pharynx wall subsides and causes can obviously improve upper airway resistance.Can reduce asphyxia number of times and apneic time effectively like this, confirm that electrostimulation treatment OSAS is effective really, but the not good part of its method: need to be percutaneous vertically to thrust 4-4.5cm, to be difficult for accepting for the patient like this; In addition, need night the doctor on duty by the patient, the sleep state of monitored patient gives electricity irritation when patient respiratory suspends.

Summary of the invention: the purpose of this utility model is based on the current experiments result, it is lower, safe and effective easy to use to provide in a kind of therapeutic process the patient not have uncomfortable sensation, noiseless, cost, it is on duty to need not the medical worker during use, even the noinvasive transcutaneous electrostimulation device of patient's treatment obstructive sleep apnea syndrome that can use in the own home.

For realizing above-mentioned purpose of the present utility model, described noinvasive transcutaneous electrostimulation device comprises several non-built-in mode percutaneous electrodes 23, asphyxia pick off and electric stimulation pulse string generator, described electric stimulation pulse string generator comprises by microprocessing unit able to programme, the memory under program ROM cell, chip microprocessor programmable pulse control system that the data memory ram cell is formed and electric stimulation pulse string produce circuit, chip microprocessor programmable pulse control system is provided with several outfans and input, the electric stimulation pulse string produces circuit and is provided with trigger end and the pulse output channel that pulse produces, described non-built-in mode percutaneous electrode 23 is connected with the pulse output channel, the outfan of chip microprocessor programmable pulse control system is connected the train of pulse that control electric stimulation pulse string generation circuit generation parameter meets with the trigger end that the electric stimulation pulse string produces circuit, and input is connected with the asphyxia pick off gathers sleep parameters; The boost pulse parameter comprise at least the boost pulse string pulse amplitude, persistent period and apart from one another by; Chip microprocessor programmable pulse control system also is provided with the nonvolatile memory unit, and described nonvolatile memory unit is used to store boost pulse string parameter and the sleep parameters of patient under the train of pulse of this parameter stimulates.

Further solution of the present utility model is that the waveform of the train of pulse generation boost pulse that system produced is positive and negative bidirectional pulse, and a delay time is arranged between the positive negative pulse stuffing.Further solution of the present utility model is that the positive and negative bi-directional charge of boost pulse equates that wherein negative-going pulse plays the nerve fiber unpolarizing; Direct impulse is the exponential damping pulse, plays the electric charge balanced action, and making the net charge of taking in when stimulating is zero.

Further solution of the present utility model is that the asphyxia pick off comprises mouth and nose pneumatic sensor, breast abdominal respiration pick off and transcutaneous oxygen saturation pick off.

Further solution of the present utility model is that therapeutic apparatus also is provided with the communication interface that carries out data communication with personal computer mutually.

Further solution of the present utility model is that therapeutic apparatus also is provided with acoustic-optic alarm, and the train of pulse of therapeutic apparatus produces system also can produce the wake up stimulus pulse.

The noinvasive transcutaneous electrostimulation device of treatment obstructive sleep apnea syndrome of the present utility model is compared with other therapeutic modality, following advantage is arranged: 1, can be when unmanned, microprocessor is by the sleep state of the constantly automatic monitored patient of asphyxia pick off, when detecting the patient asphyxia take place or/and blood oxygen saturation when descending, after single-chip microcomputer (Microcontroller) is done intellectual analysis and is handled these signals, draw the intensity that to send electrical stimulation signal, direction, time span and cycle, then by being arranged on the transcutaneous electrostimulation electrode 23 of jaw lower area, send electrical stimulation signal, the open pharyngeal cavity to stimulate lingualis that tongue body is travelled forward, thereby reduction upper airway resistance, under the condition that does not influence sleep, reach therapeutic purposes; 2, make opportunity, intensity and the time span of automatic feedback regulation electricity irritation by single-chip microcomputer, just in case electricity irritation is inoperative and the vim and vigour saturation is crossed low or during the asphyxia overlong time, can send the stimulus signal that wakes the patient up, and in time send alarm signal, in order to avoid anoxia causes sudden death; 3, single-chip microcomputer is using patient's optimum detected parameters and electrical stimulation parameters to be stored in Nonvolatile memory inside, for calling at any time the time spent patient's next time or second angel; 4, simultaneously, the sleep parameters that is taken place overnight all is recorded in the internal memory of single-chip microcomputer,, sends in the computer, do analysis for the medical worker by wired or wireless transmission.

The utility model is described in further detail below in conjunction with accompanying drawing, provides embodiment simultaneously.

Description of drawings:

Fig. 1 is this utility model embodiment theory diagram;

Fig. 2 is this utility model embodiment outline drawing;

Fig. 3 is this utility model electrode embodiment front view;

Fig. 4 is this utility model electrode embodiment rearview;

Fig. 5 is that this utility model electrode embodiment A-A is to cutaway view;

Fig. 6 is that this utility model embodiment train of pulse produces circuit theory diagrams;

Fig. 7 is this utility model profile embodiment bonnet figure;

The specific embodiment: Fig. 1 has represented whole system of the present utility model, comprise several non-built-in mode percutaneous electrodes 23, asphyxia pick off and electric stimulation pulse string generator, electric stimulation pulse string generator is core with the microprocessor, because single-chip microcomputer inside has been integrated with CPU 10, memory under program ROM cell 12, data memory ram cell 11, select for use single-chip microcomputer to help reduced volume, the selection of chip microprocessor should be considered its memory under program, data memory capacity and input/output terminal number need satisfy system requirements, preferred microprocessor is Alim6759, certainly, under the prerequisite that does not deviate from scope of the present utility model and design, can adopt other suitable microcontroller, as Winbond W78E58.CPU 10 in this circuit is all operations of CPU control minute book system, data memory 11 is used for all operations data information of effective reading and recording native system, read-only memory under program 12 is used for the storage system control sequence, chip microprocessor programmable pulse control system also is provided with nonvolatile memory EEPORM unit 13, nonvolatile memory 13 is used to store boost pulse string parameter and the sleep parameters of patient under the train of pulse of this parameter stimulates, make the medical worker answer the people and the data of different treatment stimulation protocol according to the patient is predetermined, in addition, also the keeping records patient uses the situation of native system, adopting the purpose of nonvolatile memory 13 is to hinder for some reason in order to prevent, battery loss class reason causes down circuitry and causes losing of significant data, be provided with four outfan CRG in the CPU 10, DISCRG, TEST, OUT and three asphyxia pick off inputs, mouth and nose pneumatic sensor 17, the signal of breast abdominal respiration pick off 18 and transcutaneous oxygen saturation pick off 19 is connected to three asphyxia pick off inputs respectively after amplifying unit 16 amplifies; Train of pulse produces circuit 22 and adopts following physical circuit: as shown in Figure 6, the other end of positive source Vcc after inductance L 25 and the anodal series connection of diode D26 is as an end PAl of pulse passage, be connected to storage capacitor C29 between diode D26 negative pole and the power cathode, cross-over connection has NPN type audion Q31 between diode D26 positive terminal and the power cathode, charging end CRG is connected to audion Q31 base stage through resistance R 30, also be parallel with the series arm of resistance R 27 and NPN type audion Q37 on the storage capacitor C29, discharge end DisCRG is connected on the audion Q37 base stage through resistance R 28, the emitter stage of positive-negative-positive audion Q32 is drawn the other end PA2 as pulse paths, be connected to the series arm of resistance R 35 and NPN type audion Q36 between base stage and the power cathode, outfan OUT is connected to audion Q36 base stage through resistance R 37, test lead Test is connected to colelctor electrode through resistance R 33, and colelctor electrode is to being connected to stabilivolt W34 between the power cathode.The amplitude of pulse, width, the time that keeps, by CPU 10 controls, shown in Figure 2, during CPU 10 work, outfan CRG output low level, outfan OUT exports high level, control audion Q31 ends, audion Q32, audion Q36 conducting, battery is by inductance L 25, diode D26, electrode 23PAl, PA2, audion Q32, Q36 forms current loop, CPU is by controlling resistance R28, audion Q31, audion Q32, their corresponding conductings of audion Q37, deadline, be controlled at electrode 23PAl thereby reach, the amplitude of the last formation of PA2 boost pulse, the width persistent period, will guarantee that in the selection of component parameters train of pulse produces circuit and can send the stimulus signal that wakes the patient up, Test is used for detecting electrode 23 to have or not and come off.Electrode 23 is disposable, has a circular paper substrate 20, substrate center is provided with aperture, the aperture both sides respectively are fixed with sequin, and by the mutual electrical communication of aperture, can adopt the mode of spot welding, adopt the copper buckle 21 that uses in the clothing in the present embodiment, the one side that is provided with circular protrusions in the copper buckle is fixed on the substrate, the another side of Kou Heing is welded on the end of pulse passage lead-in wire with it, in order to improve the electric conductivity with contact skin, apply one deck electric silica gel 24 on the buckle of electrode 23, and scribble adhesive sticker be convenient to electrode 23 is fixed on skin surface on substrate 20, electrode 23 can be fastened and connected by the copper buckle with being connected of pulse passage, electrode 23 is changed very convenient, as Fig. 3, as Fig. 4, as shown in Figure 5.

The circuit part of whole therapeutic instrument is contained in the quadrate can 1, as shown in Figure 2, panel 8 is provided with 3 display lamps of being made up of different color LEDs 2,3,3 display lamps 2 of a selector switch are represented breathing respectively, are stimulated output and asphyxia, working power socket 4 and the serial line interface socket 5 that is connected with PC are arranged on the bonnet 6, also be provided with the input socket 7 of an electrode 23 sockets 9 and three pick offs on the bonnet 6, respectively corresponding external tapping nasal respiration pick off, breast abdominal respiration pick off and oximetry sensor.

Claims (6)

1, a kind of noinvasive transcutaneous electrostimulation device for the treatment of obstructive sleep apnea syndrome, it is characterized in that: described noinvasive transcutaneous electrostimulation device comprises several non-built-in mode percutaneous electrodes, asphyxia pick off and electric stimulation pulse string generator, described electric stimulation pulse string generator comprises by microprocessing unit able to programme (10), memory under program ROM cell (12), chip microprocessor programmable pulse control system that data memory ram cell (11) is formed and electric stimulation pulse string produce circuit (22), chip microprocessor programmable pulse control system is provided with several outfans and input, the electric stimulation pulse string produces circuit (22) and is provided with trigger end and the pulse output channel that pulse produces, described non-built-in mode percutaneous electrode 23 is connected with the pulse output channel, the outfan of chip microprocessor programmable pulse control system is connected the train of pulse that control electric stimulation pulse string generation circuit (22) generation parameter meets with the trigger end that the electric stimulation pulse string produces circuit (22), and input is connected with the asphyxia pick off gathers sleep parameters; The boost pulse parameter comprise at least the boost pulse string pulse amplitude, persistent period and apart from one another by; Chip microprocessor programmable pulse control system also is provided with nonvolatile memory unit (13), and described nonvolatile memory unit (13) is used to store boost pulse string parameter and the sleep parameters of patient under the train of pulse of this parameter stimulates.

2, the noinvasive transcutaneous electrostimulation device of treatment obstructive sleep apnea syndrome according to claim 1, it is characterized in that: the waveform that described train of pulse produces the boost pulse that system produced is positive and negative bidirectional pulse, and a delay time is arranged between the positive negative pulse stuffing.

3, the noinvasive transcutaneous electrostimulation device of treatment obstructive sleep apnea syndrome according to claim 2 is characterized in that: the positive and negative bi-directional charge of described boost pulse equates that wherein negative-going pulse plays the nerve fiber unpolarizing; Direct impulse is the exponential damping pulse, plays the electric charge balanced action, and making the net charge of taking in when stimulating is zero.

4, according to the noinvasive transcutaneous electrostimulation device of claim 1 or 2 or 3 described treatment obstructive sleep apnea syndromes, it is characterized in that: described asphyxia pick off comprises mouth and nose pneumatic sensor (17), breast abdominal respiration pick off (18) and transcutaneous oxygen saturation pick off (19).

5, the noinvasive transcutaneous electrostimulation device of treatment obstructive sleep apnea syndrome according to claim 4 is characterized in that: described therapeutic apparatus also is provided with the communication interface (14) that carries out data communication with personal computer mutually.

6, according to the noinvasive transcutaneous electrostimulation device of the described treatment obstructive sleep apnea syndrome of claim 1, it is characterized in that: described therapeutic apparatus also is provided with acoustic-optic alarm, and the train of pulse of therapeutic apparatus produces system also can produce the wake up stimulus pulse.

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