DE3587036T2 - Verfahren und reagenziensystem zur differentiellen bestimmung vierer populationen von leukozyten. - Google Patents
Verfahren und reagenziensystem zur differentiellen bestimmung vierer populationen von leukozyten.Info
- Publication number
- DE3587036T2 DE3587036T2 DE8585902786T DE3587036T DE3587036T2 DE 3587036 T2 DE3587036 T2 DE 3587036T2 DE 8585902786 T DE8585902786 T DE 8585902786T DE 3587036 T DE3587036 T DE 3587036T DE 3587036 T2 DE3587036 T2 DE 3587036T2
- Authority
- DE
- Germany
- Prior art keywords
- leucocytes
- populations
- reagent system
- differential determination
- differential
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Ecology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/615,966 US4751179A (en) | 1984-05-31 | 1984-05-31 | Method and reagents for differential determination of four populations of leukocytes in blood |
PCT/US1985/000868 WO1985005684A1 (en) | 1984-05-31 | 1985-05-09 | Method and reagent system for four-population differential determination of leukocytes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3587036D1 DE3587036D1 (de) | 1993-03-11 |
DE3587036T2 true DE3587036T2 (de) | 1993-09-02 |
Family
ID=24467496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585902786T Expired - Fee Related DE3587036T2 (de) | 1984-05-31 | 1985-05-09 | Verfahren und reagenziensystem zur differentiellen bestimmung vierer populationen von leukozyten. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4751179A (de) |
EP (1) | EP0185048B1 (de) |
JP (1) | JPS61502277A (de) |
KR (1) | KR860700153A (de) |
AU (1) | AU4401985A (de) |
CA (1) | CA1248856A (de) |
DE (1) | DE3587036T2 (de) |
ES (1) | ES8609727A1 (de) |
WO (1) | WO1985005684A1 (de) |
Families Citing this family (87)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5188935A (en) * | 1984-05-31 | 1993-02-23 | Coulter Electronics, Inc. | Reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes |
CA1255197A (en) * | 1984-09-24 | 1989-06-06 | Joseph L. Orlik | Leukocyte differentiation composition and method |
US5175109A (en) * | 1986-09-10 | 1992-12-29 | Toa Medical Electronics Co., Ltd. | Reagent for classifying leukocytes by flow cytometry |
JPH06100596B2 (ja) * | 1986-09-10 | 1994-12-12 | 東亜医用電子株式会社 | フロ−サイトメトリ−による白血球の分類方法 |
US4791355A (en) * | 1986-10-21 | 1988-12-13 | Coulter Electronics Inc. | Particle analyzer for measuring the resistance and reactance of a particle |
US5179026A (en) * | 1986-11-27 | 1993-01-12 | Toa Medical Electronics Co., Ltd. | Method of classifying leukocytes by flow cytometry and reagents used in the method |
US5039613A (en) * | 1986-11-27 | 1991-08-13 | Toa Medical Electronics Co., Ltd. | Reagents used in a method of classifying leukocytes by flow cytometry |
KR970007077B1 (ko) * | 1987-03-13 | 1997-05-02 | 코울터 일렉트로닉스 인커퍼레이티드 | 광산란 기술을 이용한 다중-부분식별 분석 방법 |
US5155044A (en) * | 1987-03-13 | 1992-10-13 | Coulter Electronics, Inc. | Lysing reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples |
US6159740A (en) * | 1987-03-13 | 2000-12-12 | Coulter Corporation | Method and apparatus for screening obscured or partially obscured cells |
IL85532A (en) * | 1987-03-13 | 1992-03-29 | Coulter Electronics | Method and lytic reagent system for isolation,identification and/or analysis of leukocytes from whole blood samples |
US5389549A (en) * | 1987-05-29 | 1995-02-14 | Toa Medical Electronics Co., Ltd. | Method for classifying leukocytes and a reagent used therefor |
JP2635142B2 (ja) * | 1987-05-29 | 1997-07-30 | 東亜医用電子株式会社 | 白血球分類方法および試薬 |
JP2619900B2 (ja) * | 1988-01-27 | 1997-06-11 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬および方法 |
US5408307A (en) * | 1988-07-11 | 1995-04-18 | Omron Tateisi Electronics Co. | Cell analyzer |
US5089384A (en) * | 1988-11-04 | 1992-02-18 | Amoco Corporation | Method and apparatus for selective cell destruction using amplified immunofluorescence |
CA2016699C (en) * | 1989-05-15 | 2003-11-18 | Paul N. Marshall | Lytic agents and uses thereof |
FR2654744B1 (fr) * | 1989-11-20 | 1992-03-13 | Abx Sa | Reactif et methode d'utilisation de celui-ci pour la determination automatique en cytometrie de flux d'au moins une sous-population leucocytaire a partir du sang total. |
JP2815435B2 (ja) * | 1989-12-22 | 1998-10-27 | 株式会社日立製作所 | 粒子解析装置及び血球カウンタ |
JP2941041B2 (ja) * | 1990-11-16 | 1999-08-25 | シスメックス株式会社 | フローサイトメトリーによる白血球の分類方法 |
US5270208A (en) * | 1991-05-09 | 1993-12-14 | Streck Laboratories, Inc. | White blood cell hematology control |
US5316725A (en) * | 1991-06-07 | 1994-05-31 | Edward Lawrence Carver, Jr. | Reagent system for the improved determination of white blood cell subpopulations |
US5262329A (en) * | 1991-06-13 | 1993-11-16 | Carver Jr Edward L | Method for improved multiple species blood analysis |
JP3048260B2 (ja) * | 1991-07-29 | 2000-06-05 | シスメックス株式会社 | 白血球分類計数用試料調製方法 |
JP3067849B2 (ja) * | 1991-07-29 | 2000-07-24 | シスメックス株式会社 | 白血球分類計数用試料調製方法 |
US5776709A (en) * | 1991-08-28 | 1998-07-07 | Becton Dickinson And Company | Method for preparation and analysis of leukocytes in whole blood |
JP2565844B2 (ja) * | 1992-02-07 | 1996-12-18 | アボツト・ラボラトリーズ | 細胞溶解処理条件下で異種細胞集団を正確に計数し,感受性に関する格付けを行う方法 |
US5451525A (en) * | 1992-02-14 | 1995-09-19 | Coulter Corporation | Method and materials for determining particle count in a flow cytometer |
WO1993017329A1 (en) * | 1992-02-24 | 1993-09-02 | Coulter Corporation | Suspension media for hematological composition and method for its use |
US6509192B1 (en) * | 1992-02-24 | 2003-01-21 | Coulter International Corp. | Quality control method |
ATE195810T1 (de) * | 1992-02-24 | 2000-09-15 | Coulter Corp | Hämatologisches kontrollprodukt mit leukozytenanalogen; und methoden zu ihrer herstellung und anwendung |
US6362003B1 (en) | 1992-02-24 | 2002-03-26 | Coulter Corporation | Hematological reference control composition containing leukocyte analogs, methods of making, and uses thereof |
JPH08501208A (ja) * | 1992-06-12 | 1996-02-13 | ジェン−プローブ・インコーポレイテッド | 血液から核酸の製造 |
AU2095992A (en) * | 1992-08-11 | 1994-03-24 | Abbott Laboratories | Flow cytometry sheath reagent for elimination of red cells with preservation of nucleated cells |
DE69327775T2 (de) * | 1992-11-19 | 2000-06-21 | Sysmex Corp | Verfahren zur Vorbehandlung für Blutanalyse |
JP2716267B2 (ja) * | 1993-02-25 | 1998-02-18 | アボツト・ラボラトリーズ | 全血試料を高速溶解するための多目的試薬系 |
JP3301646B2 (ja) | 1993-03-19 | 2002-07-15 | シスメックス株式会社 | 幼若細胞測定用試薬 |
JP3707620B2 (ja) * | 1993-05-14 | 2005-10-19 | コールター インターナショナル コーポレイション | 光散乱技術を使用した網赤血球分析方法と装置 |
DE4330213C2 (de) * | 1993-09-07 | 1995-08-10 | Patscheke Heinrich | Mittel zur Stabilisierung von Blut |
US5631165A (en) * | 1994-08-01 | 1997-05-20 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
CA2193971C (en) * | 1994-08-01 | 2000-10-31 | Vernon L. Chupp | Pseudo telecentric optical design for flow cytometric blood cell analyzer |
US5656499A (en) * | 1994-08-01 | 1997-08-12 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
US5891734A (en) * | 1994-08-01 | 1999-04-06 | Abbott Laboratories | Method for performing automated analysis |
US5879900A (en) * | 1994-12-15 | 1999-03-09 | Abbott Laboratories | Method for simultaneous analysis of cell viability, nucleated red blood cells and white blood cell differentials |
US5559037A (en) * | 1994-12-15 | 1996-09-24 | Abbott Laboratories | Method for rapid and simultaneous analysis of nucleated red blood cells |
JPH10503285A (ja) * | 1995-04-28 | 1998-03-24 | コールター インターナショナル コーポレイション | 血液学的器具の品質コントロール法 |
DE19520298A1 (de) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Sortiervorrichtung für biologische Zellen oder Viren |
FR2735578B1 (fr) * | 1995-06-13 | 1997-09-05 | Hycel Groupe Lisabio | Reactif de lyse des erythrocytes, et son utilisation dans des procedes d'isolement et de discrimination des leucocytes |
US5817518A (en) * | 1995-12-18 | 1998-10-06 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
EP0944829B1 (de) * | 1996-12-11 | 2003-07-02 | Amersham plc | Selektives verfahren zur lyse von zellen |
US6146901A (en) * | 1997-06-16 | 2000-11-14 | Hematronix, Inc. | Composition for manipulating optical and electrical properties of particles to achieve target values for such properties and methods for using the composition |
US6106779A (en) * | 1997-10-02 | 2000-08-22 | Biosite Diagnostics, Inc. | Lysis chamber for use in an assay device |
FR2781055B1 (fr) * | 1998-07-09 | 2000-10-13 | Immunotech Sa | Reactif et methode pour la permeabilisation et l'identification des erythrocytes |
FR2782166B1 (fr) * | 1998-08-04 | 2000-10-06 | Abx Sa | Reactif pour la mesure de l'hemoglobine et la determination des leucocytes dans un echantillon de sang |
FR2782730B1 (fr) | 1998-08-25 | 2002-05-17 | Biocom Sa | Procede de separation cellulaire pour l'isolation de cellules pathogeniques, notamment cancereuses rares, equipement et reactif pour la mise en oeuvre du procede et application du procede |
US6221668B1 (en) | 1999-08-20 | 2001-04-24 | Streck Laboratories, Inc. | Hematology control and system for multi-parameter hematology measurements |
US6200500B1 (en) | 1999-08-20 | 2001-03-13 | Streck Laboratories, Inc. | Hematology control and system for multi-parameter hematology measurements |
US20020098589A1 (en) * | 2001-01-19 | 2002-07-25 | Crews Harold Richardson | Multi-purpose reagent system and method for enumeration of red blood cells, white blood cells and thrombocytes and differential determination of white blood cells |
US6514763B2 (en) | 2000-04-28 | 2003-02-04 | Hematronix, Inc. | Hematology blood control and method for preparation of same |
DE60212343T2 (de) * | 2001-02-02 | 2007-06-14 | Cellomics, Inc. | Verfahren zur schätzung der besten anfangsfokussierung |
FR2821428B1 (fr) * | 2001-02-23 | 2004-08-06 | Abx Sa | Reactif et procede pour l'identification et le comptage de cellules biologiques |
US20030119080A1 (en) * | 2001-10-15 | 2003-06-26 | Mangano Joseph A. | Strategies for the identification and isolation of cancer stem cells and non-cancerous stem cells |
US6653137B2 (en) | 2001-12-03 | 2003-11-25 | Streck Laboratories Inc. | Hematology reference control |
US6723563B2 (en) | 2001-12-03 | 2004-04-20 | Streck Laboratories Inc. | Hematology reference control |
WO2003104772A1 (en) * | 2002-06-01 | 2003-12-18 | Chempaq A/S | A disposable cartridge for characterizing particles suspended in a liquid |
CN1874720B (zh) | 2003-09-03 | 2010-11-17 | 生命修复国际股份有限公司 | 个人诊断装置 |
AU2006212607B2 (en) | 2005-02-10 | 2010-12-09 | Koninklijke Philips Electronics N.V. | Dual sample cartridge and method for characterizing particle in liquid |
US8028566B2 (en) * | 2005-02-10 | 2011-10-04 | Chempaq A/S | Dual sample cartridge and method for characterizing particles in liquid |
EP2030013B1 (de) | 2006-06-06 | 2009-12-16 | Roche Diagnostics GmbH | Gebrauchsfertiges sammelgefäss für vollblut |
JP5156738B2 (ja) | 2006-06-06 | 2013-03-06 | エフ.ホフマン−ラ ロシュ アーゲー | 全血試料の特異的溶血 |
WO2008030154A1 (en) * | 2006-09-08 | 2008-03-13 | Hemocue Ab | Haemolysing agent |
CN101349644B (zh) * | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
CN101464454B (zh) * | 2007-12-18 | 2016-08-03 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类试剂及方法 |
CN105440725A (zh) * | 2008-01-04 | 2016-03-30 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 |
US20110027826A1 (en) * | 2008-05-02 | 2011-02-03 | Arkray, Inc. | Leukocyte analysis method and analysis reagent for use in the method |
CN101602762B (zh) * | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
US20100086962A1 (en) * | 2008-10-08 | 2010-04-08 | Streck, Inc. | Hematology controls and methods |
CN101726579B (zh) * | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
US8367358B2 (en) * | 2008-12-17 | 2013-02-05 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Reagent, kit and method for differentiating and counting leukocytes |
EP2259045A1 (de) * | 2009-06-05 | 2010-12-08 | Koninklijke Philips Electronics N.V. | Multifrequenz-Impedanzverfahren und Vorrichtung zur Unterscheidung und Zählung von Partikeln, die einen spezifischen Marker exprimieren |
EP2259044A1 (de) * | 2009-06-05 | 2010-12-08 | Koninklijke Philips Electronics N.V. | Multifrequenz-Impedanzverfahren und Vorrichtung zur Unterscheidung und Zählung von Partikeln, die einen spezifischen Marker exprimieren |
CN101988082B (zh) * | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
WO2014143332A1 (en) * | 2013-03-12 | 2014-09-18 | Abbott Laboratories | Reagents, systems and methods for analyzing white blood cells |
WO2016106688A1 (zh) * | 2014-12-31 | 2016-07-07 | 深圳迈瑞生物医疗电子股份有限公司 | 一种有核红细胞报警方法、装置及流式细胞分析仪 |
EP3286324B1 (de) * | 2015-04-20 | 2020-05-20 | Qiagen GmbH | Verfahren, lyselösung und ausrüstung zur selektiven abreicherung von tierischen nukleinsäuren in einer probe |
JP7143678B2 (ja) * | 2018-08-24 | 2022-09-29 | 東ソー株式会社 | 標的細胞を検出する方法 |
CN116097093A (zh) * | 2020-09-03 | 2023-05-09 | 生物辐射实验室股份有限公司 | 制备有核rbc(nrbc)类似物用作自动化血液分析仪中的参比血液对照 |
Family Cites Families (21)
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US2656508A (en) * | 1949-08-27 | 1953-10-20 | Wallace H Coulter | Means for counting particles suspended in a fluid |
US3259842A (en) * | 1959-08-19 | 1966-07-05 | Coulter Electronics | Particle analyzing device |
US3446751A (en) * | 1965-11-29 | 1969-05-27 | Brunswick Corp | Hemolyzing composition |
US3502974A (en) * | 1966-05-23 | 1970-03-24 | Coulter Electronics | Signal modulated apparatus for generating and detecting resistive and reactive changes in a modulated current path for particle classification and analysis |
US3741875A (en) * | 1970-10-30 | 1973-06-26 | Mount Sinai Res Foundation Inc | Process and apparatus for obtaining a differential white blood cell count |
BE790042A (nl) * | 1971-10-14 | 1973-04-13 | Coulter Electronics | Werkwijze voor het classifiseren van deeltjes |
BE793185A (fr) * | 1971-12-23 | 1973-04-16 | Atomic Energy Commission | Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques |
US4146604A (en) * | 1973-05-31 | 1979-03-27 | Block Engineering, Inc. | Differential counting of leukocytes and other cells |
US3884579A (en) * | 1973-06-14 | 1975-05-20 | Cambridge Chemical Products In | Method for counting blood platelets |
US3883247A (en) * | 1973-10-30 | 1975-05-13 | Bio Physics Systems Inc | Method for fluorescence analysis of white blood cells |
US3873467A (en) * | 1974-02-01 | 1975-03-25 | United Medical Lab Inc | Hematologic reference control |
US4198206A (en) * | 1977-06-13 | 1980-04-15 | Ryan Wayne L | Method for preparing a platelet reference control |
US4099917A (en) * | 1977-07-21 | 1978-07-11 | Technicon Instruments Corporation | Process for preparing a cell suspension from blood for discrimination of white blood cells and platelets from other blood particles |
US4213876A (en) * | 1978-08-22 | 1980-07-22 | Coulter Electronics, Inc. | Multi-purpose blood diluent for use in electronic blood analysis instrumentation |
US4250051A (en) * | 1978-12-26 | 1981-02-10 | Coulter Electronics, Inc. | Preservative for use in calibrator compositions for blood analysis |
US4286963A (en) * | 1979-11-23 | 1981-09-01 | Coulter Electronics, Inc. | Differential lymphoid-myeloid determination of leukocytes in whole blood |
US4521518A (en) * | 1980-06-16 | 1985-06-04 | Coulter Electronics, Inc. | Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes |
US4500509A (en) * | 1981-03-11 | 1985-02-19 | Lawrence Kass | Metachromatic dye sorption and fluorescent light emmisive means for differential determination of developmental stages of neutrophilic granulocytic cells and other leukocytes |
US4492752A (en) * | 1982-09-03 | 1985-01-08 | Ortho Diagnostics Systems Inc. | Method for discriminating between unstained and absorbing dye stained cells |
US4506018A (en) * | 1982-12-30 | 1985-03-19 | Becton, Dickinson And Company | Blood diluent |
US4485175A (en) * | 1983-01-03 | 1984-11-27 | Coulter Electronics, Inc. | Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes |
-
1984
- 1984-05-31 US US06/615,966 patent/US4751179A/en not_active Expired - Lifetime
-
1985
- 1985-05-09 EP EP85902786A patent/EP0185048B1/de not_active Expired - Lifetime
- 1985-05-09 DE DE8585902786T patent/DE3587036T2/de not_active Expired - Fee Related
- 1985-05-09 WO PCT/US1985/000868 patent/WO1985005684A1/en active IP Right Grant
- 1985-05-09 AU AU44019/85A patent/AU4401985A/en not_active Abandoned
- 1985-05-09 JP JP60502359A patent/JPS61502277A/ja active Pending
- 1985-05-30 ES ES543657A patent/ES8609727A1/es not_active Expired
- 1985-05-30 CA CA000482841A patent/CA1248856A/en not_active Expired
-
1986
- 1986-01-30 KR KR1019860700056A patent/KR860700153A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPS61502277A (ja) | 1986-10-09 |
DE3587036D1 (de) | 1993-03-11 |
EP0185048A4 (de) | 1988-09-28 |
CA1248856A (en) | 1989-01-17 |
ES8609727A1 (es) | 1986-08-16 |
EP0185048B1 (de) | 1993-01-27 |
AU4401985A (en) | 1985-12-31 |
KR860700153A (ko) | 1986-03-31 |
WO1985005684A1 (en) | 1985-12-19 |
US4751179A (en) | 1988-06-14 |
ES543657A0 (es) | 1986-08-16 |
EP0185048A1 (de) | 1986-06-25 |
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