DE50015938D1 - Polypeptidvarianten mit erhoehter heparin-bindungsfaehigkeit - Google Patents

Polypeptidvarianten mit erhoehter heparin-bindungsfaehigkeit

Info

Publication number
DE50015938D1
DE50015938D1 DE50015938T DE50015938T DE50015938D1 DE 50015938 D1 DE50015938 D1 DE 50015938D1 DE 50015938 T DE50015938 T DE 50015938T DE 50015938 T DE50015938 T DE 50015938T DE 50015938 D1 DE50015938 D1 DE 50015938D1
Authority
DE
Germany
Prior art keywords
sub
polypeptide variants
increased heparin
binding capacity
heparin binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50015938T
Other languages
English (en)
Inventor
Walter Sebald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osteopharma Inc
Original Assignee
Osteopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteopharma Inc filed Critical Osteopharma Inc
Priority to DE50015938T priority Critical patent/DE50015938D1/de
Application granted granted Critical
Publication of DE50015938D1 publication Critical patent/DE50015938D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DE50015938T 1999-02-13 2000-01-27 Polypeptidvarianten mit erhoehter heparin-bindungsfaehigkeit Expired - Lifetime DE50015938D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE50015938T DE50015938D1 (de) 1999-02-13 2000-01-27 Polypeptidvarianten mit erhoehter heparin-bindungsfaehigkeit

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19906096A DE19906096A1 (de) 1999-02-13 1999-02-13 Protein mit einem Heparin-bindenden Epitop
DE50015938T DE50015938D1 (de) 1999-02-13 2000-01-27 Polypeptidvarianten mit erhoehter heparin-bindungsfaehigkeit
PCT/EP2000/000637 WO2000047736A1 (de) 1999-02-13 2000-01-27 Polypeptidvarianten mit erhöhter heparin-bindungsfähigkeit

Publications (1)

Publication Number Publication Date
DE50015938D1 true DE50015938D1 (de) 2010-07-22

Family

ID=7897433

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19906096A Ceased DE19906096A1 (de) 1999-02-13 1999-02-13 Protein mit einem Heparin-bindenden Epitop
DE50015938T Expired - Lifetime DE50015938D1 (de) 1999-02-13 2000-01-27 Polypeptidvarianten mit erhoehter heparin-bindungsfaehigkeit

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19906096A Ceased DE19906096A1 (de) 1999-02-13 1999-02-13 Protein mit einem Heparin-bindenden Epitop

Country Status (11)

Country Link
US (1) US7253254B1 (de)
EP (1) EP1151095B1 (de)
JP (3) JP4155711B2 (de)
CN (1) CN1169959C (de)
AT (1) ATE470713T1 (de)
AU (1) AU762387B2 (de)
BR (1) BR0008785A (de)
CA (1) CA2362496C (de)
DE (2) DE19906096A1 (de)
RU (1) RU2227743C2 (de)
WO (1) WO2000047736A1 (de)

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US9216212B2 (en) 2005-08-05 2015-12-22 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
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US20080206299A1 (en) * 2007-02-27 2008-08-28 Shimp Lawrence A Method for Recovering Minerals From Bone and Use of Same
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US9554920B2 (en) 2007-06-15 2017-01-31 Warsaw Orthopedic, Inc. Bone matrix compositions having nanoscale textured surfaces
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US9492278B2 (en) 2007-07-10 2016-11-15 Warsaw Orthopedic, Inc. Delivery system
JP2009045142A (ja) * 2007-08-16 2009-03-05 Okayama Univ 生体内にて基材周囲に骨形成を誘導するための基材処理方法
WO2010039224A2 (en) 2008-09-30 2010-04-08 University Of Massachusetts Medical School Respiratory syncytial virus (rsv) sequences for protein expression and vaccines
JP5799409B2 (ja) * 2008-12-19 2015-10-28 国立大学法人 新潟大学 ヘパリン親和性エリスロポエチン
US9011537B2 (en) 2009-02-12 2015-04-21 Warsaw Orthopedic, Inc. Delivery system cartridge
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US10919948B2 (en) 2016-12-30 2021-02-16 Biogend Therapeutics Co., Ltd. Recombinant polypeptides, compositions, and methods thereof

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Also Published As

Publication number Publication date
RU2227743C2 (ru) 2004-04-27
ATE470713T1 (de) 2010-06-15
AU762387B2 (en) 2003-06-26
CN1340102A (zh) 2002-03-13
JP2009011323A (ja) 2009-01-22
JP2008086319A (ja) 2008-04-17
CN1169959C (zh) 2004-10-06
US7253254B1 (en) 2007-08-07
JP4155711B2 (ja) 2008-09-24
DE19906096A1 (de) 2000-08-17
EP1151095B1 (de) 2010-06-09
WO2000047736A1 (de) 2000-08-17
CA2362496A1 (en) 2000-08-17
AU2110600A (en) 2000-08-29
JP2002536016A (ja) 2002-10-29
EP1151095A1 (de) 2001-11-07
CA2362496C (en) 2011-04-19
BR0008785A (pt) 2001-11-06

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