DE60115005D1 - Formulierungen mit verzögerter freisetzung enthaltend wachstumshormon - Google Patents
Formulierungen mit verzögerter freisetzung enthaltend wachstumshormonInfo
- Publication number
- DE60115005D1 DE60115005D1 DE60115005T DE60115005T DE60115005D1 DE 60115005 D1 DE60115005 D1 DE 60115005D1 DE 60115005 T DE60115005 T DE 60115005T DE 60115005 T DE60115005 T DE 60115005T DE 60115005 D1 DE60115005 D1 DE 60115005D1
- Authority
- DE
- Germany
- Prior art keywords
- growth hormone
- formulations
- delayed release
- containing growth
- release containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH] (Somatotropin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19820900P | 2000-04-19 | 2000-04-19 | |
US198209P | 2000-04-19 | ||
PCT/US2001/012909 WO2001078683A2 (en) | 2000-04-19 | 2001-04-19 | Sustained release formulations comprising growth hormone |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60115005D1 true DE60115005D1 (de) | 2005-12-22 |
DE60115005T2 DE60115005T2 (de) | 2006-07-27 |
Family
ID=22732439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60115005T Expired - Lifetime DE60115005T2 (de) | 2000-04-19 | 2001-04-19 | Formulierungen mit verzögerter freisetzung enthaltend wachstumshormon |
Country Status (11)
Country | Link |
---|---|
US (1) | US6992065B2 (de) |
EP (1) | EP1274459B1 (de) |
JP (1) | JP4361710B2 (de) |
AT (1) | ATE309822T1 (de) |
AU (2) | AU2001259111B2 (de) |
CA (1) | CA2406790C (de) |
DE (1) | DE60115005T2 (de) |
DK (1) | DK1274459T3 (de) |
ES (1) | ES2253375T3 (de) |
IL (1) | IL152360A0 (de) |
WO (1) | WO2001078683A2 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7318931B2 (en) * | 2001-06-21 | 2008-01-15 | Genentech, Inc. | Sustained release formulation |
US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
DE10242088A1 (de) * | 2002-09-11 | 2004-03-25 | Bayer Ag | Kontrolliertes Freisetzungssystem, welches Saccharoseacetatisobutyrat enthält |
CA2507522C (en) | 2002-12-13 | 2015-02-24 | Durect Corporation | Oral drug delivery system |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
BR0317421A (pt) * | 2002-12-19 | 2005-11-08 | Alza Corp | Géis de fase única não-aquosa estável e formulações destes para liberação a partir de um dispositivo implantável |
DE10312346A1 (de) * | 2003-03-20 | 2004-09-30 | Bayer Healthcare Ag | Kontrolliertes Freisetzungssystem |
EP1708734A4 (de) * | 2004-01-07 | 2009-06-17 | Trimeris Inc | Von hiv gp41 hr2 abgeleitete peptide und deren verwendung in der therapie zur hemmung der übertragung des humanen immundefizienzvirus |
LT2767292T (lt) * | 2004-09-17 | 2016-12-12 | Durect Corporation | Palaikomosios vietinės anestezijos mišinys su saib |
JP2008528509A (ja) * | 2005-01-21 | 2008-07-31 | アルザ コーポレイション | 少なくとも1つの対イオンを含む、向上した安定性でマイクロニードルをコーティングするための治療用ペプチド製剤 |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
EP2361630A1 (de) * | 2005-02-03 | 2011-08-31 | Intarcia Therapeutics, Inc | Implantierbares Arzneimittelfreigabesystem Partikel und eine osmotische Pumpe enthaltend |
EP3081215B9 (de) | 2005-05-23 | 2020-08-19 | Natural Alternatives International, Inc. | Zusammensetzungen und verfahren zur anhaltenden freisetzung von beta-alanin |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
US7456251B2 (en) | 2006-02-02 | 2008-11-25 | Trimeris, Inc. | HIV fusion inhibitor peptides with improved biological properties |
CN101453982B (zh) | 2006-05-30 | 2011-05-04 | 精达制药公司 | 两件式内部通道渗透递送系统流动调节器 |
ES2422864T3 (es) | 2006-08-09 | 2013-09-16 | Intarcia Therapeutics, Inc | Sistemas de liberación osmótica y unidades de pistón |
US8337883B2 (en) | 2006-11-03 | 2012-12-25 | Durect Corporation | Transdermal delivery systems |
US20080140106A1 (en) * | 2006-12-12 | 2008-06-12 | Kimberly-Clark Worldwide, Inc. | Enhanced cuff sealing for endotracheal tubes |
AU2007234612B2 (en) * | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
KR20100016142A (ko) * | 2007-04-03 | 2010-02-12 | 트라이머리스, 인코퍼레이티드 | 항바이러스 펩티드 치료제 전달용 신규 제제 |
RU2440097C2 (ru) | 2007-04-23 | 2012-01-20 | Интарсия Терапьютикс, Инк. | Способ лечения диабета ii типа и ожирения, осмотическое устройство для доставки и способ его изготовления |
US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
CA2695697A1 (en) | 2007-08-07 | 2009-02-12 | Advanced Technologies And Regenerative Medicine, Llc | Protein formulations comprising gdf-5 in aqueous acidic solution |
MX2010003179A (es) * | 2007-09-25 | 2010-04-30 | Trimeris Inc | Metodos de sintesis para peptidos anti-vih terapeuticos. |
US8114883B2 (en) | 2007-12-04 | 2012-02-14 | Landec Corporation | Polymer formulations for delivery of bioactive materials |
CA2706658A1 (en) | 2007-12-06 | 2009-06-18 | Durect Corporation | Methods useful for the treatment of pain, arthritic conditions or inflammation associated with a chronic condition |
US20090181068A1 (en) | 2008-01-14 | 2009-07-16 | Dunn Richard L | Low Viscosity Liquid Polymeric Delivery System |
US8586103B2 (en) * | 2008-02-08 | 2013-11-19 | Foresee Pharmaceuticals, Llc | Non-polymeric compositions for controlled drug delivery |
CA2714506C (en) | 2008-02-08 | 2016-06-07 | Qps Llc | Composition for sustained release delivery of proteins or peptides |
EP2240155B1 (de) | 2008-02-13 | 2012-06-06 | Intarcia Therapeutics, Inc | Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe |
AU2009236459B2 (en) | 2008-04-14 | 2013-07-25 | Advanced Technologies And Regenerative Medicine, Llc | Liquid buffered GDF-5 formulations |
US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
EP3323423B1 (de) | 2009-09-28 | 2020-06-17 | Intarcia Therapeutics, Inc | Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel |
BR112012014721B1 (pt) | 2009-12-15 | 2022-06-28 | Ascendis Pharma Endocrinology Division A/S | Composições de hormônio do crescimento, seus métodos de fabricação, recipiente e kit |
EA026964B1 (ru) * | 2010-11-24 | 2017-06-30 | Дьюрект Корпорейшн | Биоразлагаемая композиция для доставки лекарственного средства (варианты) |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
ITMI20110445A1 (it) * | 2011-03-22 | 2012-09-23 | Lo Li Pharma Srl | Formulazione farmaceutica comprendente inositolo. |
CN103127514B (zh) * | 2011-11-22 | 2014-07-02 | 朱成钢 | 一种可体内注射的药物缓释栓剂 |
CN102389571B (zh) * | 2011-11-22 | 2013-04-24 | 朱成钢 | 一种可体内注射的药物缓释栓剂 |
CN105120659A (zh) | 2013-03-15 | 2015-12-02 | 度瑞公司 | 用于降低溶解可变性的具有流变改性剂的组合物 |
US20160303242A1 (en) | 2013-12-09 | 2016-10-20 | Durect Corporation | Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
EP3302354B1 (de) | 2015-06-03 | 2023-10-04 | i2o Therapeutics, Inc. | Systeme zum einsetzen eines implantats |
WO2017200943A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
WO2019060921A1 (en) | 2017-09-25 | 2019-03-28 | Bolt Threads, Inc. | METHODS OF GENERATING HIGHLY CRYSTALLINE RECOMBINANT SPIDER SILK PROTEIN FIBERS |
WO2020033970A2 (en) * | 2018-08-10 | 2020-02-13 | Bolt Threads, Inc. | Composition for a molded body |
CA3167217A1 (en) | 2020-01-13 | 2021-07-22 | Durect Corporation | Sustained release drug delivery systems with reduced impurities and related methods |
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-
2001
- 2001-04-19 EP EP01932596A patent/EP1274459B1/de not_active Expired - Lifetime
- 2001-04-19 AT AT01932596T patent/ATE309822T1/de not_active IP Right Cessation
- 2001-04-19 IL IL15236001A patent/IL152360A0/xx not_active IP Right Cessation
- 2001-04-19 ES ES01932596T patent/ES2253375T3/es not_active Expired - Lifetime
- 2001-04-19 DK DK01932596T patent/DK1274459T3/da active
- 2001-04-19 WO PCT/US2001/012909 patent/WO2001078683A2/en active IP Right Grant
- 2001-04-19 JP JP2001575984A patent/JP4361710B2/ja not_active Expired - Fee Related
- 2001-04-19 US US09/839,684 patent/US6992065B2/en not_active Expired - Fee Related
- 2001-04-19 CA CA002406790A patent/CA2406790C/en not_active Expired - Fee Related
- 2001-04-19 AU AU2001259111A patent/AU2001259111B2/en not_active Ceased
- 2001-04-19 AU AU5911101A patent/AU5911101A/xx active Pending
- 2001-04-19 DE DE60115005T patent/DE60115005T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE309822T1 (de) | 2005-12-15 |
CA2406790A1 (en) | 2001-10-25 |
DE60115005T2 (de) | 2006-07-27 |
DK1274459T3 (da) | 2006-02-06 |
ES2253375T3 (es) | 2006-06-01 |
WO2001078683A2 (en) | 2001-10-25 |
EP1274459A2 (de) | 2003-01-15 |
JP4361710B2 (ja) | 2009-11-11 |
AU2001259111B2 (en) | 2005-12-08 |
IL152360A0 (en) | 2003-05-29 |
JP2004500423A (ja) | 2004-01-08 |
CA2406790C (en) | 2009-07-07 |
EP1274459B1 (de) | 2005-11-16 |
US20020001631A1 (en) | 2002-01-03 |
WO2001078683A3 (en) | 2002-05-30 |
AU5911101A (en) | 2001-10-30 |
US6992065B2 (en) | 2006-01-31 |
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