DE60140317D1 - Verfahren und kits zur verbesserung der hybridisierungsraten von polynukleotiden - Google Patents

Verfahren und kits zur verbesserung der hybridisierungsraten von polynukleotiden

Info

Publication number
DE60140317D1
DE60140317D1 DE60140317T DE60140317T DE60140317D1 DE 60140317 D1 DE60140317 D1 DE 60140317D1 DE 60140317 T DE60140317 T DE 60140317T DE 60140317 T DE60140317 T DE 60140317T DE 60140317 D1 DE60140317 D1 DE 60140317D1
Authority
DE
Germany
Prior art keywords
polynucleotides
kits
improving
hybridization rates
complementary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60140317T
Other languages
English (en)
Inventor
Michael M Becker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Application granted granted Critical
Publication of DE60140317D1 publication Critical patent/DE60140317D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
DE60140317T 2000-12-14 2001-12-07 Verfahren und kits zur verbesserung der hybridisierungsraten von polynukleotiden Expired - Lifetime DE60140317D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25553500P 2000-12-14 2000-12-14
PCT/US2001/048592 WO2002048404A2 (en) 2000-12-14 2001-12-07 Method and kit for enhancing the association rates of polynucleotides

Publications (1)

Publication Number Publication Date
DE60140317D1 true DE60140317D1 (de) 2009-12-10

Family

ID=22968766

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60140317T Expired - Lifetime DE60140317D1 (de) 2000-12-14 2001-12-07 Verfahren und kits zur verbesserung der hybridisierungsraten von polynukleotiden

Country Status (8)

Country Link
US (2) US7374945B2 (de)
EP (1) EP1377679B1 (de)
JP (1) JP2004537263A (de)
AT (1) ATE447043T1 (de)
AU (2) AU2002230901B2 (de)
CA (1) CA2436857A1 (de)
DE (1) DE60140317D1 (de)
WO (1) WO2002048404A2 (de)

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US6919180B2 (en) * 2002-03-22 2005-07-19 Sigma Genosys, L.P. Hybridization rate enhancement for substrate-bound specific nucleic acid-binding agents
DE10237284A1 (de) * 2002-08-14 2004-03-04 Advalytix Ag Nukleinsäurenachweis
KR101137572B1 (ko) * 2003-06-11 2012-05-30 이데라 파마슈티칼즈, 인코포레이티드 안정화된 면역조절 올리고뉴클레오티드
WO2006063065A2 (en) * 2004-12-08 2006-06-15 Gen-Probe Incorporated Detection of nucleic acids from multiple types of human papillomaviruses
JP5187847B2 (ja) * 2005-05-06 2013-04-24 ジェン−プローブ・インコーポレーテッド 核酸標的の捕獲方法
US7488581B2 (en) * 2006-03-20 2009-02-10 Kabushiki Kaisha Toshiba Method for detecting a target nucleic acid sequence
EP3733871A1 (de) * 2008-05-27 2020-11-04 Dako Denmark A/S Zusammensetzungen und verfahren zur erkennung von chromosomalen abweichungen mit neuen hybridisierungspuffern
WO2010097655A1 (en) * 2009-02-26 2010-09-02 Dako Denmark A/S Compositions and methods for rna hybridization applications
US10662465B2 (en) 2011-09-30 2020-05-26 Agilent Technologies, Inc. Hybridization compositions and methods using formamide
EP2766498B1 (de) 2011-10-14 2019-06-19 President and Fellows of Harvard College Sequenzierung durch strukturanordnung
EP2768974B1 (de) 2011-10-21 2017-07-19 Dako Denmark A/S Hybridisierungszusammensetzungen und -verfahren
US11021737B2 (en) 2011-12-22 2021-06-01 President And Fellows Of Harvard College Compositions and methods for analyte detection
EP4249605A3 (de) 2011-12-22 2023-11-15 President And Fellows Of Harvard College Verfahren zum nachweis von analyten
WO2013184754A2 (en) 2012-06-05 2013-12-12 President And Fellows Of Harvard College Spatial sequencing of nucleic acids using dna origami probes
US10138509B2 (en) 2013-03-12 2018-11-27 President And Fellows Of Harvard College Method for generating a three-dimensional nucleic acid containing matrix
AU2016349288A1 (en) 2015-11-03 2018-05-31 President And Fellows Of Harvard College Method and apparatus for volumetric imaging of a three-dimensional nucleic acid containing matrix
WO2017189525A1 (en) 2016-04-25 2017-11-02 President And Fellows Of Harvard College Hybridization chain reaction methods for in situ molecular detection
CN109923216A (zh) 2016-08-31 2019-06-21 哈佛学院董事及会员团体 将生物分子的检测组合到使用荧光原位测序的单个试验的方法
JP7239465B2 (ja) * 2016-08-31 2023-03-14 プレジデント アンド フェローズ オブ ハーバード カレッジ 蛍光ｉｎ ｓｉｔｕ配列決定による検出のための核酸配列ライブラリの作製法
US11185568B2 (en) 2017-04-14 2021-11-30 President And Fellows Of Harvard College Methods for generation of cell-derived microfilament network
CN110650703B (zh) * 2017-05-05 2023-05-12 史赛克欧洲运营有限公司 手术导航系统
EP3836967A4 (de) 2018-07-30 2022-06-15 ReadCoor, LLC Verfahren und systeme zur probenverarbeitung oder -analyse
EP3830302B1 (de) * 2018-08-01 2022-10-05 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis von nukleinsäuren des epstein-barr-virus
CN109988842B (zh) * 2019-04-19 2022-12-06 上海吉玛制药技术有限公司 一种寡核苷酸标记探针原位检测pdl1的试剂组与应用
JP7428951B2 (ja) * 2021-12-10 2024-02-07 日東紡績株式会社 核酸の対象塩基配列中における変異を検出するための方法、核酸の増幅を選択的に阻害する方法、およびこれらを実施するためのキット
JP7394301B2 (ja) * 2021-12-10 2023-12-08 日東紡績株式会社 二本鎖核酸の融解温度上昇化剤及びその用途

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WO1999011813A2 (en) * 1997-09-04 1999-03-11 Bayer Corporation Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof
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AU6093300A (en) 1999-07-14 2001-02-05 Genometrix Genomics Incorporated Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them
US6297016B1 (en) * 1999-10-08 2001-10-02 Applera Corporation Template-dependent ligation with PNA-DNA chimeric probes
US6380377B1 (en) * 2000-07-14 2002-04-30 Applied Gene Technologies, Inc. Nucleic acid hairpin probes and uses thereof
US6448407B1 (en) * 2000-11-01 2002-09-10 Pe Corporation (Ny) Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis
US20040265823A1 (en) * 2001-08-24 2004-12-30 Atsushi Maruyama Method of judging mismatch between single-stranded nucleic acid molecules
JP5034027B2 (ja) * 2005-10-03 2012-09-26 株式会社Ｍｏｒｅｓｃｏ パーフルオロポリエーテル化合物、およびこれを用いた潤滑剤ならびに磁気ディスク

Also Published As

Publication number Publication date
CA2436857A1 (en) 2002-06-20
AU3090102A (en) 2002-06-24
JP2004537263A (ja) 2004-12-16
AU2002230901B2 (en) 2006-09-07
US7374945B2 (en) 2008-05-20
ATE447043T1 (de) 2009-11-15
EP1377679A2 (de) 2004-01-07
WO2002048404A3 (en) 2003-10-23
US20020164614A1 (en) 2002-11-07
US20040077014A1 (en) 2004-04-22
EP1377679B1 (de) 2009-10-28
WO2002048404A2 (en) 2002-06-20

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