DE60232819D1 - Verwendung von vernetztem kollagen zur behandlung von bandscheiben - Google Patents
Verwendung von vernetztem kollagen zur behandlung von bandscheibenInfo
- Publication number
- DE60232819D1 DE60232819D1 DE60232819T DE60232819T DE60232819D1 DE 60232819 D1 DE60232819 D1 DE 60232819D1 DE 60232819 T DE60232819 T DE 60232819T DE 60232819 T DE60232819 T DE 60232819T DE 60232819 D1 DE60232819 D1 DE 60232819D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- therapeutic method
- discs
- belts
- tissues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/044—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33714501P | 2001-12-10 | 2001-12-10 | |
PCT/IL2002/000997 WO2003049669A2 (en) | 2001-12-10 | 2002-12-10 | Methods, devices, and preparations for intervertebral disc treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60232819D1 true DE60232819D1 (de) | 2009-08-13 |
Family
ID=23319301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60232819T Expired - Lifetime DE60232819D1 (de) | 2001-12-10 | 2002-12-10 | Verwendung von vernetztem kollagen zur behandlung von bandscheiben |
Country Status (11)
Country | Link |
---|---|
US (1) | US20040010251A1 (de) |
EP (1) | EP1465558B1 (de) |
JP (1) | JP2005511207A (de) |
AT (1) | ATE434996T1 (de) |
AU (1) | AU2002358957A1 (de) |
BR (1) | BRPI0215131A8 (de) |
CA (1) | CA2482309A1 (de) |
DE (1) | DE60232819D1 (de) |
IL (1) | IL162419A0 (de) |
MX (1) | MXPA04005707A (de) |
WO (1) | WO2003049669A2 (de) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6402750B1 (en) * | 2000-04-04 | 2002-06-11 | Spinlabs, Llc | Devices and methods for the treatment of spinal disorders |
US6805695B2 (en) * | 2000-04-04 | 2004-10-19 | Spinalabs, Llc | Devices and methods for annular repair of intervertebral discs |
US6723335B1 (en) * | 2000-04-07 | 2004-04-20 | Jeffrey William Moehlenbruck | Methods and compositions for treating intervertebral disc degeneration |
US8022101B2 (en) * | 2001-08-31 | 2011-09-20 | Orthopeutics, L.P. | Method of treating a knee meniscus with a cross-linking reagent to increase resistance to tearing or rupturing |
TW200526203A (en) * | 2001-08-31 | 2005-08-16 | Univ Southern California | Non-toxic crosslinking reagents to resist curve progression in scoliosis and increase disc permeability |
US20070202143A1 (en) * | 2001-08-31 | 2007-08-30 | Hedman Thomas P | Direct application of non-toxic crosslinking reagents to restabilize surgically destabilized intervertebral joints |
AU2003245251A1 (en) * | 2002-05-01 | 2003-11-17 | Verigen Ag | Injectable chondrocyte implant |
US7744651B2 (en) * | 2002-09-18 | 2010-06-29 | Warsaw Orthopedic, Inc | Compositions and methods for treating intervertebral discs with collagen-based materials |
US20040054414A1 (en) * | 2002-09-18 | 2004-03-18 | Trieu Hai H. | Collagen-based materials and methods for augmenting intervertebral discs |
CN101198297A (zh) * | 2002-09-18 | 2008-06-11 | 华沙整形外科股份有限公司 | 扩增椎间盘的胶原材料和方法 |
CN100394989C (zh) * | 2002-11-15 | 2008-06-18 | 华沙整形外科股份有限公司 | 包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节 |
US20040186471A1 (en) * | 2002-12-07 | 2004-09-23 | Sdgi Holdings, Inc. | Method and apparatus for intervertebral disc expansion |
AU2004208821B2 (en) * | 2003-01-31 | 2009-01-15 | Zimmer Orthobiologics Inc. | Hydrogel compositions comprising nucleus pulposus tissue |
CN1774220A (zh) | 2003-02-14 | 2006-05-17 | 德普伊斯派尔公司 | 原位成型的椎间融合器械和方法 |
US7344716B2 (en) * | 2003-05-13 | 2008-03-18 | Depuy Spine, Inc. | Transdiscal administration of specific inhibitors of pro-inflammatory cytokines |
US7452351B2 (en) | 2004-04-16 | 2008-11-18 | Kyphon Sarl | Spinal diagnostic methods and apparatus |
US7824390B2 (en) | 2004-04-16 | 2010-11-02 | Kyphon SÀRL | Spinal diagnostic methods and apparatus |
US20060122704A1 (en) * | 2004-07-27 | 2006-06-08 | Synthes Inc. | Supplementation or replacement of a nucleus pulposus of an intervertebral disc |
JP2008511420A (ja) | 2004-08-30 | 2008-04-17 | スピネオベイションズ・インコポレーテッド | 脊髄の椎間板内障害の治療の方法 |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
US8016744B2 (en) * | 2005-02-24 | 2011-09-13 | Ethicon Endo-Surgery, Inc. | External pressure-based gastric band adjustment system and method |
US8366773B2 (en) | 2005-08-16 | 2013-02-05 | Benvenue Medical, Inc. | Apparatus and method for treating bone |
JP4944111B2 (ja) * | 2005-08-16 | 2012-05-30 | ベンベニュー メディカル, インコーポレイテッド | 脊柱組織伸延装置 |
EP1937701A4 (de) * | 2005-09-02 | 2009-09-16 | Colbar Lifescience Ltd | Quervernetzte polysaccharid- und proteinmatrizen und verfahren zu ihrer herstellung |
US20070065415A1 (en) * | 2005-09-16 | 2007-03-22 | Kleinsek Donald A | Compositions and methods for the augmentation and repair of defects in tissue |
WO2007089233A1 (en) * | 2006-02-02 | 2007-08-09 | Tom Hedman | Direct application of non-toxic crosslinking reagents to resist progressive spinal deformity |
US8118779B2 (en) * | 2006-06-30 | 2012-02-21 | Warsaw Orthopedic, Inc. | Collagen delivery device |
US20080004703A1 (en) * | 2006-06-30 | 2008-01-03 | Warsaw Orthopedic, Inc. | Method of treating a patient using a collagen material |
US20080004431A1 (en) * | 2006-06-30 | 2008-01-03 | Warsaw Orthopedic Inc | Method of manufacturing an injectable collagen material |
US8399619B2 (en) * | 2006-06-30 | 2013-03-19 | Warsaw Orthopedic, Inc. | Injectable collagen material |
US20080082170A1 (en) * | 2006-09-29 | 2008-04-03 | Peterman Marc M | Apparatus and methods for surgical repair |
WO2008070863A2 (en) | 2006-12-07 | 2008-06-12 | Interventional Spine, Inc. | Intervertebral implant |
WO2008083153A2 (en) * | 2006-12-28 | 2008-07-10 | Mi4Spine, Llc | Vertebral disc annular fibrosis tensioning and lengthening device |
EP2124777A4 (de) * | 2007-02-21 | 2013-06-05 | Benvenue Medical Inc | Vorrichtungen zur wirbelsäulenbehandlung |
EP2124778B1 (de) | 2007-02-21 | 2019-09-25 | Benvenue Medical, Inc. | Vorrichtungen zur wirbelsäulenbehandlung |
US10278947B2 (en) | 2007-02-28 | 2019-05-07 | Orthopeutics, L.P. | Crosslinker enhanced repair of connective tissues |
US8864801B2 (en) * | 2007-04-30 | 2014-10-21 | Warsaw Orthopedic, Inc. | Method of deformity correction in a spine using injectable materials |
US8900307B2 (en) | 2007-06-26 | 2014-12-02 | DePuy Synthes Products, LLC | Highly lordosed fusion cage |
US8328738B2 (en) * | 2007-06-29 | 2012-12-11 | Actuated Medical, Inc. | Medical tool for reduced penetration force with feedback means |
US9987468B2 (en) | 2007-06-29 | 2018-06-05 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US10219832B2 (en) | 2007-06-29 | 2019-03-05 | Actuated Medical, Inc. | Device and method for less forceful tissue puncture |
CN101909548B (zh) | 2008-01-17 | 2014-07-30 | 斯恩蒂斯有限公司 | 可膨胀椎间植入件以及制造它的相关方法 |
US8469961B2 (en) | 2008-03-05 | 2013-06-25 | Neville Alleyne | Methods and compositions for minimally invasive capsular augmentation of canine coxofemoral joints |
JP5441997B2 (ja) | 2008-04-05 | 2014-03-12 | ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 拡張可能な椎骨間インプラント |
US8535327B2 (en) | 2009-03-17 | 2013-09-17 | Benvenue Medical, Inc. | Delivery apparatus for use with implantable medical devices |
US9526620B2 (en) | 2009-03-30 | 2016-12-27 | DePuy Synthes Products, Inc. | Zero profile spinal fusion cage |
US9044335B2 (en) | 2009-05-05 | 2015-06-02 | Cornell University | Composite tissue-engineered intervertebral disc with self-assembled annular alignment |
US8814807B2 (en) * | 2009-08-19 | 2014-08-26 | Mirador Biomedical | Spinal canal access and probe positioning, devices and methods |
US9393129B2 (en) | 2009-12-10 | 2016-07-19 | DePuy Synthes Products, Inc. | Bellows-like expandable interbody fusion cage |
EP2579765B1 (de) * | 2010-06-13 | 2019-08-07 | Omeq Medical Ltd. | Vorrichtung für anatomische positionierung mit einer dehnbaren vorrichtung |
US9282979B2 (en) | 2010-06-24 | 2016-03-15 | DePuy Synthes Products, Inc. | Instruments and methods for non-parallel disc space preparation |
US8979860B2 (en) | 2010-06-24 | 2015-03-17 | DePuy Synthes Products. LLC | Enhanced cage insertion device |
WO2012003175A1 (en) | 2010-06-29 | 2012-01-05 | Synthes Usa, Llc | Distractible intervertebral implant |
US9364568B2 (en) | 2010-07-15 | 2016-06-14 | Warsaw Orthopedic, Inc. | Methods to diagnose degenerative disc disease |
US9402732B2 (en) | 2010-10-11 | 2016-08-02 | DePuy Synthes Products, Inc. | Expandable interspinous process spacer implant |
US8814873B2 (en) | 2011-06-24 | 2014-08-26 | Benvenue Medical, Inc. | Devices and methods for treating bone tissue |
US8562681B2 (en) | 2012-01-31 | 2013-10-22 | Styker Spine | Laminoplasty implant, method and instrumentation |
US9522070B2 (en) | 2013-03-07 | 2016-12-20 | Interventional Spine, Inc. | Intervertebral implant |
US10085783B2 (en) | 2013-03-14 | 2018-10-02 | Izi Medical Products, Llc | Devices and methods for treating bone tissue |
JP7004501B2 (ja) | 2013-12-03 | 2022-01-21 | コーネル ユニバーシティー | 線維輪を修復する方法及びコラーゲンゲル組成物 |
WO2015138328A2 (en) * | 2014-03-10 | 2015-09-17 | Medtrain Technologies, Llc | Collagen hydrogel kit and methods of making a collagen hydrogel |
ES2693579T3 (es) | 2015-01-16 | 2018-12-12 | Spineovations, Inc. | Método de tratamiento del disco intervertebral |
US11426290B2 (en) | 2015-03-06 | 2022-08-30 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
US10940292B2 (en) | 2015-07-08 | 2021-03-09 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US11793543B2 (en) | 2015-09-18 | 2023-10-24 | Obvius Robotics, Inc. | Device and method for automated insertion of penetrating member |
US11510788B2 (en) | 2016-06-28 | 2022-11-29 | Eit Emerging Implant Technologies Gmbh | Expandable, angularly adjustable intervertebral cages |
WO2018002715A2 (en) | 2016-06-28 | 2018-01-04 | Eit Emerging Implant Technologies Gmbh | Expandable and angularly adjustable articulating intervertebral cages |
US10888433B2 (en) | 2016-12-14 | 2021-01-12 | DePuy Synthes Products, Inc. | Intervertebral implant inserter and related methods |
US10398563B2 (en) | 2017-05-08 | 2019-09-03 | Medos International Sarl | Expandable cage |
US11344424B2 (en) | 2017-06-14 | 2022-05-31 | Medos International Sarl | Expandable intervertebral implant and related methods |
US10940016B2 (en) | 2017-07-05 | 2021-03-09 | Medos International Sarl | Expandable intervertebral fusion cage |
US11202674B2 (en) | 2018-04-03 | 2021-12-21 | Convergent Dental, Inc. | Laser system for surgical applications |
US11446156B2 (en) | 2018-10-25 | 2022-09-20 | Medos International Sarl | Expandable intervertebral implant, inserter instrument, and related methods |
US11426286B2 (en) | 2020-03-06 | 2022-08-30 | Eit Emerging Implant Technologies Gmbh | Expandable intervertebral implant |
US11850160B2 (en) | 2021-03-26 | 2023-12-26 | Medos International Sarl | Expandable lordotic intervertebral fusion cage |
US11752009B2 (en) | 2021-04-06 | 2023-09-12 | Medos International Sarl | Expandable intervertebral fusion cage |
WO2022097128A1 (en) * | 2021-12-22 | 2022-05-12 | Heydarian Mohammad | Surgeon robot minimally invasive laser lumbar disc surgery by pldd method |
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US5246457A (en) * | 1985-03-28 | 1993-09-21 | Collagen Corporation | Xenogeneic collagen/mineral preparations in bone repair |
US5108438A (en) * | 1989-03-02 | 1992-04-28 | Regen Corporation | Prosthetic intervertebral disc |
US5147514A (en) * | 1987-08-02 | 1992-09-15 | University Of North Carolina | Process for cross-linking collagenous material and resulting product |
US4772287A (en) * | 1987-08-20 | 1988-09-20 | Cedar Surgical, Inc. | Prosthetic disc and method of implanting |
AU624627B2 (en) * | 1988-08-18 | 1992-06-18 | Johnson & Johnson Orthopaedics, Inc. | Functional and biocompatible intervertebral disc spacer containing elastomeric material of varying hardness |
US4971954A (en) * | 1988-11-23 | 1990-11-20 | University Of Medicine And Dentistry Of New Jersey | Collagen-based matrices ribose cross-linked |
CA2022480C (en) * | 1989-08-02 | 2001-02-27 | Gerald L. Mechanic | Process for cross-linking collagenous materials and resulting product |
DE59100448D1 (de) * | 1990-04-20 | 1993-11-11 | Sulzer Ag | Implantat, insbesondere Zwischenwirbelprothese. |
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EP0700671B1 (de) * | 1994-09-08 | 2001-08-08 | Stryker Technologies Corporation | Bandscheibenkern aus Hydrogel |
CA2201607C (en) * | 1994-10-17 | 2001-02-13 | Charles D. Ray | Prosthetic spinal disc nucleus |
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US6126682A (en) * | 1996-08-13 | 2000-10-03 | Oratec Interventions, Inc. | Method for treating annular fissures in intervertebral discs |
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FR2787992B1 (fr) * | 1999-01-04 | 2001-04-20 | Aesculap Sa | Prothese tibiale du genou a rotule a double inserts |
US6585972B2 (en) * | 1999-03-09 | 2003-07-01 | Gholam A. Peyman | Process for crosslinking of collagen in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina |
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US6723335B1 (en) | 2000-04-07 | 2004-04-20 | Jeffrey William Moehlenbruck | Methods and compositions for treating intervertebral disc degeneration |
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US20020176893A1 (en) * | 2001-02-02 | 2002-11-28 | Wironen John F. | Compositions, implants, methods, and kits for closure of lumen openings, repair of ruptured tissue, and for bulking of tissue |
US20030069639A1 (en) * | 2001-04-14 | 2003-04-10 | Tom Sander | Methods and compositions for repair or replacement of joints and soft tissues |
AU2002336694A1 (en) * | 2001-11-01 | 2003-05-12 | Lawrence M. Boyd | Devices and methods for the restoration of a spinal disc |
US20040054414A1 (en) * | 2002-09-18 | 2004-03-18 | Trieu Hai H. | Collagen-based materials and methods for augmenting intervertebral discs |
-
2002
- 2002-12-10 US US10/315,220 patent/US20040010251A1/en not_active Abandoned
- 2002-12-10 EP EP02793301A patent/EP1465558B1/de not_active Expired - Lifetime
- 2002-12-10 JP JP2003550720A patent/JP2005511207A/ja active Pending
- 2002-12-10 CA CA002482309A patent/CA2482309A1/en not_active Abandoned
- 2002-12-10 IL IL16241902A patent/IL162419A0/xx unknown
- 2002-12-10 AT AT02793301T patent/ATE434996T1/de not_active IP Right Cessation
- 2002-12-10 WO PCT/IL2002/000997 patent/WO2003049669A2/en active Application Filing
- 2002-12-10 BR BRPI0215131A patent/BRPI0215131A8/pt not_active Application Discontinuation
- 2002-12-10 MX MXPA04005707A patent/MXPA04005707A/es unknown
- 2002-12-10 AU AU2002358957A patent/AU2002358957A1/en not_active Abandoned
- 2002-12-10 DE DE60232819T patent/DE60232819D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2482309A1 (en) | 2003-06-19 |
MXPA04005707A (es) | 2005-06-20 |
WO2003049669A2 (en) | 2003-06-19 |
EP1465558A2 (de) | 2004-10-13 |
WO2003049669A3 (en) | 2004-03-11 |
IL162419A0 (en) | 2005-11-20 |
ATE434996T1 (de) | 2009-07-15 |
AU2002358957A1 (en) | 2003-06-23 |
BR0215131A (pt) | 2005-04-26 |
EP1465558A4 (de) | 2005-03-16 |
BRPI0215131A8 (pt) | 2017-09-12 |
EP1465558B1 (de) | 2009-07-01 |
US20040010251A1 (en) | 2004-01-15 |
JP2005511207A (ja) | 2005-04-28 |
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