DE69022760T2 - Allgemeinverfahren für die Bestätigung von Krebs. - Google Patents

Allgemeinverfahren für die Bestätigung von Krebs.

Info

Publication number
DE69022760T2
DE69022760T2 DE69022760T DE69022760T DE69022760T2 DE 69022760 T2 DE69022760 T2 DE 69022760T2 DE 69022760 T DE69022760 T DE 69022760T DE 69022760 T DE69022760 T DE 69022760T DE 69022760 T2 DE69022760 T2 DE 69022760T2
Authority
DE
Germany
Prior art keywords
confirmation
cancer
general procedure
procedure
general
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69022760T
Other languages
English (en)
Other versions
DE69022760D1 (de
Inventor
Bert Vogelstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Application granted granted Critical
Publication of DE69022760D1 publication Critical patent/DE69022760D1/de
Publication of DE69022760T2 publication Critical patent/DE69022760T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
DE69022760T 1989-03-16 1990-02-20 Allgemeinverfahren für die Bestätigung von Krebs. Expired - Lifetime DE69022760T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/324,512 US5380645A (en) 1989-03-16 1989-03-16 Generalized method for assessment of colorectal carcinoma

Publications (2)

Publication Number Publication Date
DE69022760D1 DE69022760D1 (de) 1995-11-09
DE69022760T2 true DE69022760T2 (de) 1996-03-14

Family

ID=23263922

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022760T Expired - Lifetime DE69022760T2 (de) 1989-03-16 1990-02-20 Allgemeinverfahren für die Bestätigung von Krebs.

Country Status (4)

Country Link
US (2) US5380645A (de)
EP (1) EP0390324B1 (de)
JP (1) JP3152917B2 (de)
DE (1) DE69022760T2 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380645A (en) * 1989-03-16 1995-01-10 The Johns Hopkins University Generalized method for assessment of colorectal carcinoma
CA2073186C (en) * 1990-01-04 2002-06-11 Bert Vogelstein Gene deleted in colorectal cancer in humans
FR2680520B1 (fr) * 1991-08-22 1995-09-22 France Etat Armement Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique.
AT397478B (de) * 1991-10-03 1994-04-25 Voest Alpine Stahl Verfahren und vorrichtung zum stranggiessen eines dünnen bandes oder einer dünnen bramme
WO1994011531A1 (en) * 1992-11-13 1994-05-26 California Institute Of Biological Research Identification of neoplasms by detection of genetic insertions and deletions
US5492808A (en) * 1993-05-05 1996-02-20 The Johns Hopkins University Means for detecting familial colon cancer (FCC)
EP0779935A4 (de) * 1994-08-31 2006-07-19 Univ Johns Hopkins Med Die bestimmung von schnell mutierenden nukleinsäuresequenzen im gewebe
EP0782633A4 (de) * 1994-09-23 2002-01-02 Sydney D Finkelstein Topographische genotypisierung
US5702886A (en) * 1994-10-05 1997-12-30 The Johns Hopkins University Chromosome I8Q loss and prognosis in colorectal cancer
US20040254101A1 (en) * 1995-06-06 2004-12-16 Human Genome Sciences, Inc. Colon specific gene and protein and cancer
AU711346B2 (en) * 1995-06-06 1999-10-14 Human Genome Sciences, Inc. Colon specific gene and protein
US5861494A (en) * 1995-06-06 1999-01-19 Human Genome Sciences, Inc. Colon specific gene and protein
US5670325A (en) * 1996-08-14 1997-09-23 Exact Laboratories, Inc. Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
US5955279A (en) * 1996-06-13 1999-09-21 Gatti; Richard A. Ataxia-telangiectasia: mutations in the ATM gene
US5858673A (en) * 1996-06-24 1999-01-12 Charlotte-Mecklenburg Hospital Authority Method for detecting prostate cells
US5952178A (en) 1996-08-14 1999-09-14 Exact Laboratories Methods for disease diagnosis from stool samples
US6020137A (en) * 1996-08-14 2000-02-01 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US5928870A (en) * 1997-06-16 1999-07-27 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US6203993B1 (en) 1996-08-14 2001-03-20 Exact Science Corp. Methods for the detection of nucleic acids
US6300077B1 (en) 1996-08-14 2001-10-09 Exact Sciences Corporation Methods for the detection of nucleic acids
US6100029A (en) * 1996-08-14 2000-08-08 Exact Laboratories, Inc. Methods for the detection of chromosomal aberrations
US6146828A (en) * 1996-08-14 2000-11-14 Exact Laboratories, Inc. Methods for detecting differences in RNA expression levels and uses therefor
CA2410120A1 (en) * 1996-08-28 1998-03-05 The Johns Hopkins University School Of Medicine Method for detecting cell proliferative disorders
US6406857B1 (en) 1997-06-16 2002-06-18 Exact Sciences Corporation Methods for stool sample preparation
US6268136B1 (en) 1997-06-16 2001-07-31 Exact Science Corporation Methods for stool sample preparation
US20020064792A1 (en) * 1997-11-13 2002-05-30 Lincoln Stephen E. Database for storage and analysis of full-length sequences
SE9704186D0 (sv) * 1997-11-14 1997-11-14 Astra Ab New composition of matter
US7226731B1 (en) 1998-07-24 2007-06-05 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services PB 39, a gene dysregulated in prostate cancer, and uses thereof
WO2000005376A1 (en) * 1998-07-24 2000-02-03 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Pb 39, a gene dysregulated in prostate cancer, and uses thereof
WO2000009759A1 (en) * 1998-08-17 2000-02-24 The Burnham Institute Methods for identifying somatic changes in genomic sequences useful for cancer diagnosis and prognosis
US6503718B2 (en) 1999-01-10 2003-01-07 Exact Sciences Corporation Methods for detecting mutations using primer extension for detecting disease
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
AU752817B2 (en) 1999-02-25 2002-10-03 Exact Sciences Corporation Methods for preserving DNA integrity
JP4794052B2 (ja) * 1999-04-09 2011-10-12 ジェンザイム・コーポレーション 癌の指標である核酸を検出するための方法
US6586177B1 (en) * 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6919174B1 (en) * 1999-12-07 2005-07-19 Exact Sciences Corporation Methods for disease detection
CA2394921A1 (en) * 1999-12-07 2001-06-14 Anthony P. Shuber Supracolonic aerodigestive neoplasm detection
DE60125596T2 (de) * 2000-07-11 2007-10-04 Kirk Madison Hogan Verfahren und zusammensetzungen zur bestimmung von perioperativen genomprofile
US20030190602A1 (en) * 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
US20030165895A1 (en) * 2001-06-12 2003-09-04 Bogdan Czerniak Methods of detecting, diagnosing and treating cancer and identifying neoplastic progression
AU2003213107A1 (en) 2002-02-15 2003-09-09 Exact Sciences Corporation Methods for analysis of molecular events
US20060147915A1 (en) * 2002-06-27 2006-07-06 Aarhus Universitet Disease risk estimating method fusing sequence polymorphisms in a specific region of chromosome 19
CA2490280A1 (en) * 2002-07-01 2004-01-08 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
US20040259101A1 (en) * 2003-06-20 2004-12-23 Shuber Anthony P. Methods for disease screening
US20050142585A1 (en) * 2003-10-02 2005-06-30 University Of South Florida Determination of phenotype of cancer and of precancerous tissue
US20080241827A1 (en) * 2004-05-10 2008-10-02 Exact Sciences Corporation Methods For Detecting A Mutant Nucleic Acid
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
WO2006026654A2 (en) * 2004-08-27 2006-03-09 Exact Sciences Corporation Method for detecting a recombinant event
EP1809769A2 (de) * 2004-10-22 2007-07-25 Redpath Integrated Pathology, Inc. Erhöhte vervielfältigbarkeit winziger gewebeproben, winzige gefärbte zytologieproben und andere winzige dna-quellen
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) * 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
EP1945794A2 (de) * 2005-11-09 2008-07-23 Chemimage Corporation System und verfahren zur zytologischen analyse über raman-spektroskopische abbildung
US20090280491A1 (en) * 2008-03-27 2009-11-12 The Trustees Of Columbia University In The City Of New York Predicting cancer invasiveness
US9341628B2 (en) 2012-11-30 2016-05-17 Interpace Diagnostics Corporation Methods for measuring carcinoembryonic antigen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
GB8719061D0 (en) * 1987-08-12 1987-09-16 Imp Cancer Research Fund Paten Probe
US5380645A (en) * 1989-03-16 1995-01-10 The Johns Hopkins University Generalized method for assessment of colorectal carcinoma

Also Published As

Publication number Publication date
EP0390324A3 (de) 1991-08-28
EP0390324B1 (de) 1995-10-04
US5380645A (en) 1995-01-10
JP3152917B2 (ja) 2001-04-03
US5580729A (en) 1996-12-03
EP0390324A2 (de) 1990-10-03
JPH03244400A (ja) 1991-10-31
DE69022760D1 (de) 1995-11-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: PATENTANWAELTE RUFF, WILHELM, BEIER, DAUSTER & PARTNER, 70173 STUTTGART