SI9400079B
(sl)
*
|
1994-02-15 |
2003-02-28 |
Dr. Weidner Eckhard, Dipl. Ing. |
Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom
|
GB9413202D0
(en)
*
|
1994-06-30 |
1994-08-24 |
Univ Bradford |
Method and apparatus for the formation of particles
|
US6428771B1
(en)
*
|
1995-05-15 |
2002-08-06 |
Pharmaceutical Discovery Corporation |
Method for drug delivery to the pulmonary system
|
US6576264B1
(en)
*
|
1995-10-17 |
2003-06-10 |
Skyepharma Canada Inc. |
Insoluble drug delivery
|
US5874029A
(en)
*
|
1996-10-09 |
1999-02-23 |
The University Of Kansas |
Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
|
US5833891A
(en)
*
|
1996-10-09 |
1998-11-10 |
The University Of Kansas |
Methods for a particle precipitation and coating using near-critical and supercritical antisolvents
|
FR2753639B1
(fr)
|
1996-09-25 |
1998-12-11 |
|
Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede
|
US5766637A
(en)
*
|
1996-10-08 |
1998-06-16 |
University Of Delaware |
Microencapsulation process using supercritical fluids
|
DE19711393C1
(de)
*
|
1997-03-19 |
1998-08-13 |
Fraunhofer Ges Forschung |
Verfahren zum Mikroverkapseln von Partikeln
|
US6541606B2
(en)
*
|
1997-12-31 |
2003-04-01 |
Altus Biologics Inc. |
Stabilized protein crystals formulations containing them and methods of making them
|
GB9806462D0
(en)
*
|
1998-03-26 |
1998-05-27 |
Glaxo Group Ltd |
Improved compositions for inhalation
|
GB9810559D0
(en)
*
|
1998-05-15 |
1998-07-15 |
Bradford Particle Design Ltd |
Method and apparatus for particle formation
|
GB9814172D0
(en)
*
|
1998-06-30 |
1998-08-26 |
Andaris Ltd |
Formulation for inhalation
|
US6451349B1
(en)
|
1998-08-19 |
2002-09-17 |
Quadrant Healthcare (Uk) Limited |
Spray-drying process for the preparation of microparticles
|
US6051694A
(en)
*
|
1998-09-17 |
2000-04-18 |
Castor; Trevor Percival |
Method for size reduction of proteins
|
SE9804001D0
(sv)
†
|
1998-11-23 |
1998-11-23 |
Astra Ab |
New process
|
US6630121B1
(en)
|
1999-06-09 |
2003-10-07 |
The Regents Of The University Of Colorado |
Supercritical fluid-assisted nebulization and bubble drying
|
PT1196430E
(pt)
|
1999-06-29 |
2012-04-18 |
Mannkind Corp |
Purificação e estabilização de péptidos e proteínas em agentes farmacêuticos
|
US9006175B2
(en)
*
|
1999-06-29 |
2015-04-14 |
Mannkind Corporation |
Potentiation of glucose elimination
|
GB9915975D0
(en)
*
|
1999-07-07 |
1999-09-08 |
Bradford Particle Design Ltd |
Method for the formation of particles
|
US6680284B1
(en)
|
1999-07-13 |
2004-01-20 |
Degussa Ag |
Method for producing powdery particle-reduced formulations with the aid of compressed gases
|
FR2802445B1
(fr)
*
|
1999-12-15 |
2002-02-15 |
Separex Sa |
Procede et dispositif de captage de fines particules par piegeage au sein d'un melange solide de type neige carbonique
|
FR2803538B1
(fr)
*
|
1999-12-15 |
2002-06-07 |
Separex Sa |
Procede et dispositif de captage de fines particules par percolation dans un lit de granules
|
EP1242112A4
(de)
|
1999-12-21 |
2005-02-09 |
Rxkinetix Inc |
Partikel-enthaltende medikamente und methode zu deren herstellung
|
US6761909B1
(en)
*
|
1999-12-21 |
2004-07-13 |
Rxkinetix, Inc. |
Particulate insulin-containing products and method of manufacture
|
CH694686A5
(it)
*
|
2000-03-04 |
2005-06-15 |
Eco2 Sa |
Prodotto di micronizzazione di sostanze farmaceutiche.
|
US6620351B2
(en)
|
2000-05-24 |
2003-09-16 |
Auburn University |
Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer
|
US6821413B1
(en)
*
|
2000-08-31 |
2004-11-23 |
Fluidphase Technologies, Inc. |
Method and apparatus for continuous separation and reaction using supercritical fluid
|
US6562952B1
(en)
*
|
2000-10-31 |
2003-05-13 |
The University Of Kansas |
Precipitation of proteins from organic solutions
|
GB0027357D0
(en)
|
2000-11-09 |
2000-12-27 |
Bradford Particle Design Plc |
Particle formation methods and their products
|
AUPR197000A0
(en)
*
|
2000-12-08 |
2001-01-11 |
Unisearch Limited |
Synthesis of small particles
|
US6951656B2
(en)
*
|
2000-12-22 |
2005-10-04 |
Baxter International Inc. |
Microprecipitation method for preparing submicron suspensions
|
US8067032B2
(en)
|
2000-12-22 |
2011-11-29 |
Baxter International Inc. |
Method for preparing submicron particles of antineoplastic agents
|
US6977085B2
(en)
|
2000-12-22 |
2005-12-20 |
Baxter International Inc. |
Method for preparing submicron suspensions with polymorph control
|
US20030096013A1
(en)
*
|
2000-12-22 |
2003-05-22 |
Jane Werling |
Preparation of submicron sized particles with polymorph control
|
US7193084B2
(en)
*
|
2000-12-22 |
2007-03-20 |
Baxter International Inc. |
Polymorphic form of itraconazole
|
US20040256749A1
(en)
*
|
2000-12-22 |
2004-12-23 |
Mahesh Chaubal |
Process for production of essentially solvent-free small particles
|
US20050048126A1
(en)
*
|
2000-12-22 |
2005-03-03 |
Barrett Rabinow |
Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
|
US6884436B2
(en)
|
2000-12-22 |
2005-04-26 |
Baxter International Inc. |
Method for preparing submicron particle suspensions
|
US9700866B2
(en)
*
|
2000-12-22 |
2017-07-11 |
Baxter International Inc. |
Surfactant systems for delivery of organic compounds
|
US6869617B2
(en)
|
2000-12-22 |
2005-03-22 |
Baxter International Inc. |
Microprecipitation method for preparing submicron suspensions
|
EP1354581A4
(de)
*
|
2000-12-26 |
2007-07-04 |
Takeda Pharmaceutical |
Poröse substanz und verfahren zu ihrer herstellung
|
WO2002072636A2
(en)
*
|
2000-12-28 |
2002-09-19 |
Altus Biologics Inc. |
Crystals of whole antibodies and fragments thereof and methods for making and using them
|
US7708915B2
(en)
*
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
IL157346A0
(en)
*
|
2001-02-26 |
2004-02-19 |
Dompe Spa |
Apparatus and method for micron and submicron particle formation
|
US6610223B2
(en)
|
2001-03-30 |
2003-08-26 |
Picoliter Inc. |
Focused acoustic energy in the generation of solid particles
|
US6596206B2
(en)
|
2001-03-30 |
2003-07-22 |
Picoliter Inc. |
Generation of pharmaceutical agent particles using focused acoustic energy
|
US6869551B2
(en)
|
2001-03-30 |
2005-03-22 |
Picoliter Inc. |
Precipitation of solid particles from droplets formed using focused acoustic energy
|
JP2005500304A
(ja)
*
|
2001-06-21 |
2005-01-06 |
アルタス バイオロジックス インコーポレイテッド |
球状タンパク質粒子およびそれらの作製方法および使用方法
|
GB0208742D0
(en)
|
2002-04-17 |
2002-05-29 |
Bradford Particle Design Ltd |
Particulate materials
|
GB0117696D0
(en)
*
|
2001-07-20 |
2001-09-12 |
Bradford Particle Design Plc |
Particle information
|
US20080026068A1
(en)
*
|
2001-08-16 |
2008-01-31 |
Baxter Healthcare S.A. |
Pulmonary delivery of spherical insulin microparticles
|
US20060003012A9
(en)
*
|
2001-09-26 |
2006-01-05 |
Sean Brynjelsen |
Preparation of submicron solid particle suspensions by sonication of multiphase systems
|
CA2461349C
(en)
*
|
2001-09-26 |
2011-11-29 |
Baxter International Inc. |
Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
|
EP1435916B1
(de)
*
|
2001-10-10 |
2006-04-26 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Pulververarbeitung mit unter druck stehenden gasförmigen fluids
|
US7112340B2
(en)
*
|
2001-10-19 |
2006-09-26 |
Baxter International Inc. |
Compositions of and method for preparing stable particles in a frozen aqueous matrix
|
MXPA04003718A
(es)
*
|
2001-10-22 |
2004-07-30 |
Dompe Spa |
Procesamiento de fluidos supercriticos: preparacion de microparticulas de proteina y su estabilizacion.
|
WO2003047553A1
(en)
|
2001-12-07 |
2003-06-12 |
Eiffel Technologies Limited |
Synthesis of small particles
|
CA2479751C
(en)
|
2002-03-20 |
2008-06-03 |
Trent Poole |
Inhalation apparatus
|
CA2484052C
(en)
*
|
2002-04-11 |
2011-06-14 |
Medimmune Vaccines, Inc. |
Preservation of bioactive materials by spray drying
|
US7582284B2
(en)
*
|
2002-04-17 |
2009-09-01 |
Nektar Therapeutics |
Particulate materials
|
GB0216562D0
(en)
|
2002-04-25 |
2002-08-28 |
Bradford Particle Design Ltd |
Particulate materials
|
US9339459B2
(en)
|
2003-04-24 |
2016-05-17 |
Nektar Therapeutics |
Particulate materials
|
KR20060015587A
(ko)
*
|
2003-05-08 |
2006-02-17 |
넥타 쎄라퓨틱스 유케이 리미티드 |
미립물
|
US7767118B2
(en)
|
2003-06-03 |
2010-08-03 |
Ferro Corporation |
Nanoparticles from supercritical fluid antisolvent process using particle growth and agglomeration retardants
|
SG135204A1
(en)
*
|
2003-07-18 |
2007-09-28 |
Baxter Int |
Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation
|
US20050142205A1
(en)
*
|
2003-07-18 |
2005-06-30 |
Julia Rashba-Step |
Methods for encapsulating small spherical particles prepared by controlled phase separation
|
US20070092452A1
(en)
*
|
2003-07-18 |
2007-04-26 |
Julia Rashba-Step |
Methods for fabrication, uses, compositions of inhalable spherical particles
|
US20050048127A1
(en)
*
|
2003-07-22 |
2005-03-03 |
Larry Brown |
Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
|
CA2538237A1
(en)
*
|
2003-09-10 |
2005-03-24 |
Map Pharmaceuticals, Inc. |
Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation
|
WO2005042219A1
(en)
*
|
2003-10-24 |
2005-05-12 |
Ferro Corporation |
Method of forming particles
|
US7338171B2
(en)
*
|
2003-10-27 |
2008-03-04 |
Jen-Chuen Hsieh |
Method and apparatus for visual drive control
|
CN101027082A
(zh)
*
|
2004-01-12 |
2007-08-29 |
曼恩坎德公司 |
降低2型糖尿病患者血清胰岛素原水平的方法
|
EP1711163A2
(de)
*
|
2004-02-05 |
2006-10-18 |
Baxter International Inc. |
Unter verwendung von selbststabilisierenden mitteln hergestellte dispersionen
|
US7279457B2
(en)
*
|
2004-03-12 |
2007-10-09 |
Biodel, Inc. |
Rapid acting drug delivery compositions
|
US20080096800A1
(en)
*
|
2004-03-12 |
2008-04-24 |
Biodel, Inc. |
Rapid mucosal gel or film insulin compositions
|
US20080090753A1
(en)
|
2004-03-12 |
2008-04-17 |
Biodel, Inc. |
Rapid Acting Injectable Insulin Compositions
|
US20080085298A1
(en)
*
|
2004-03-12 |
2008-04-10 |
Biodel, Inc. |
Rapid Mucosal Gel or Film Insulin Compositions
|
US8728525B2
(en)
*
|
2004-05-12 |
2014-05-20 |
Baxter International Inc. |
Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
|
AU2005244851B2
(en)
*
|
2004-05-12 |
2010-08-26 |
Baxter Healthcare S.A. |
Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
|
CN103393601A
(zh)
|
2004-05-12 |
2013-11-20 |
巴克斯特国际公司 |
含有蛋白并在高浓度蛋白下显示可注射性的微球体
|
JP2007537284A
(ja)
*
|
2004-05-12 |
2007-12-20 |
バクスター インターナショナル インコーポレイテッド |
核酸マイクロスフェア、その生成および送達
|
ES2385934T3
(es)
|
2004-08-20 |
2012-08-03 |
Mannkind Corporation |
Catálisis de la síntesis de dicetopiperazina.
|
KR101644250B1
(ko)
|
2004-08-23 |
2016-07-29 |
맨카인드 코포레이션 |
약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
|
MX2007013356A
(es)
*
|
2005-04-27 |
2008-03-26 |
Baxter Int |
Microparticulas modificadas en la superficie y metodos de formacion y uso de las mismas.
|
ES2285605T3
(es)
*
|
2005-06-11 |
2007-11-16 |
Tutech Innovation Gmbh |
Procedimiento para la microencapsulacion de sustancias organicas en forma de particula mediante rociado de un gas soporte hipercritico inerte junto con material de recubrimiento para las sustancias organicas en un lecho fluidizado de alta presion en un autoclave.
|
US20060280787A1
(en)
*
|
2005-06-14 |
2006-12-14 |
Baxter International Inc. |
Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
|
US20060280786A1
(en)
*
|
2005-06-14 |
2006-12-14 |
Rabinow Barrett E |
Pharmaceutical formulations for minimizing drug-drug interactions
|
DK1928423T3
(en)
|
2005-09-14 |
2016-02-29 |
Mannkind Corp |
A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces
|
WO2007041481A1
(en)
*
|
2005-09-29 |
2007-04-12 |
Biodel, Inc. |
Rapid acting and prolonged acting insulin preparations
|
US7713929B2
(en)
|
2006-04-12 |
2010-05-11 |
Biodel Inc. |
Rapid acting and long acting insulin combination formulations
|
US8084420B2
(en)
*
|
2005-09-29 |
2011-12-27 |
Biodel Inc. |
Rapid acting and long acting insulin combination formulations
|
WO2007059515A2
(en)
*
|
2005-11-15 |
2007-05-24 |
Baxter International, Inc. |
Compositions of lipoxygenase inhibitors
|
CA2639925C
(en)
|
2006-01-24 |
2016-07-12 |
Nexbio, Inc. |
Technology for preparation of macromolecular microspheres
|
US8039431B2
(en)
|
2006-02-22 |
2011-10-18 |
Mannkind Corporation |
Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
|
MX2008013165A
(es)
*
|
2006-04-12 |
2009-01-29 |
Biodel Inc |
Formulaciones de combinacion de insulina de accion rapida y accion larga.
|
DE102006020148A1
(de)
*
|
2006-05-02 |
2007-11-08 |
Universität Bremen |
Gentechnisch hergestelltes Perlucin und seine Verwendung zur Herstellung von Biomaterialien
|
US20070281031A1
(en)
*
|
2006-06-01 |
2007-12-06 |
Guohan Yang |
Microparticles and methods for production thereof
|
WO2008019346A2
(en)
*
|
2006-08-04 |
2008-02-14 |
Baxter International Inc. |
Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
|
WO2008060786A2
(en)
*
|
2006-10-06 |
2008-05-22 |
Baxter International Inc. |
Microencapsules containing surface-modified microparticles and methods of forming and using the same
|
US20090152176A1
(en)
*
|
2006-12-23 |
2009-06-18 |
Baxter International Inc. |
Magnetic separation of fine particles from compositions
|
PL2425820T3
(pl)
*
|
2007-02-11 |
2015-08-31 |
Map Pharmaceuticals Inc |
Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych
|
WO2008124522A2
(en)
*
|
2007-04-04 |
2008-10-16 |
Biodel, Inc. |
Amylin formulations
|
US20080293814A1
(en)
*
|
2007-05-22 |
2008-11-27 |
Deepak Tiwari |
Concentrate esmolol
|
US8426467B2
(en)
*
|
2007-05-22 |
2013-04-23 |
Baxter International Inc. |
Colored esmolol concentrate
|
US8722736B2
(en)
*
|
2007-05-22 |
2014-05-13 |
Baxter International Inc. |
Multi-dose concentrate esmolol with benzyl alcohol
|
US8785396B2
(en)
|
2007-10-24 |
2014-07-22 |
Mannkind Corporation |
Method and composition for treating migraines
|
US20090175840A1
(en)
*
|
2008-01-04 |
2009-07-09 |
Biodel, Inc. |
Insulin formulations for insulin release as a function of tissue glucose levels
|
US8485180B2
(en)
|
2008-06-13 |
2013-07-16 |
Mannkind Corporation |
Dry powder drug delivery system
|
AU2009257311B2
(en)
|
2008-06-13 |
2014-12-04 |
Mannkind Corporation |
A dry powder inhaler and system for drug delivery
|
US9364619B2
(en)
|
2008-06-20 |
2016-06-14 |
Mannkind Corporation |
Interactive apparatus and method for real-time profiling of inhalation efforts
|
TWI532497B
(zh)
|
2008-08-11 |
2016-05-11 |
曼凱公司 |
超快起作用胰島素之用途
|
US20100047292A1
(en)
*
|
2008-08-20 |
2010-02-25 |
Baxter International Inc. |
Methods of processing microparticles and compositions produced thereby
|
US8323615B2
(en)
*
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing multi-phasic dispersions
|
US8323685B2
(en)
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
US8367427B2
(en)
*
|
2008-08-20 |
2013-02-05 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
WO2010065387A1
(en)
*
|
2008-12-01 |
2010-06-10 |
Innovative Technologies, Inc. |
Improved preparation of organic compounds for enhanced reactivity
|
US8314106B2
(en)
|
2008-12-29 |
2012-11-20 |
Mannkind Corporation |
Substituted diketopiperazine analogs for use as drug delivery agents
|
US9060927B2
(en)
*
|
2009-03-03 |
2015-06-23 |
Biodel Inc. |
Insulin formulations for rapid uptake
|
JP5667095B2
(ja)
|
2009-03-11 |
2015-02-12 |
マンカインド コーポレイション |
吸入器の抵抗を測定するための装置、システムおよび方法
|
CA2764505C
(en)
|
2009-06-12 |
2018-09-25 |
Mannkind Corporation |
Diketopiperazine microparticles with defined specific surface areas
|
WO2011056889A1
(en)
|
2009-11-03 |
2011-05-12 |
Mannkind Corporation |
An apparatus and method for simulating inhalation efforts
|
RU2571331C1
(ru)
|
2010-06-21 |
2015-12-20 |
Маннкайнд Корпорейшн |
Системы и способы доставки сухих порошковых лекарств
|
US9138705B2
(en)
|
2010-11-22 |
2015-09-22 |
Hong Kong Polytechnic University |
Method for precipitating a solute from a solution
|
US9808030B2
(en)
|
2011-02-11 |
2017-11-07 |
Grain Processing Corporation |
Salt composition
|
CN105667994B
(zh)
|
2011-04-01 |
2018-04-06 |
曼金德公司 |
用于药物药盒的泡罩包装
|
WO2012174472A1
(en)
|
2011-06-17 |
2012-12-20 |
Mannkind Corporation |
High capacity diketopiperazine microparticles
|
CA2852536A1
(en)
|
2011-10-24 |
2013-05-02 |
Mannkind Corporation |
Methods and compositions for treating pain
|
DK3574897T3
(da)
|
2011-11-18 |
2022-04-04 |
Regeneron Pharma |
Formulering med forlænget frigivelse, omfattende polymerproteinmikropartikler til anvendelse i øjets glaslegeme til behandling af vaskulære øjenlidelser
|
US20140099380A1
(en)
|
2012-06-28 |
2014-04-10 |
Ansun Biopharma, Inc. |
Microparticle Formulations for Delivery to the Lower and Central Respiratory Tract and Methods of Manufacture
|
US9802012B2
(en)
|
2012-07-12 |
2017-10-31 |
Mannkind Corporation |
Dry powder drug delivery system and methods
|
US10159644B2
(en)
|
2012-10-26 |
2018-12-25 |
Mannkind Corporation |
Inhalable vaccine compositions and methods
|
ES2754388T3
(es)
|
2013-03-15 |
2020-04-17 |
Mannkind Corp |
Composiciones y métodos de dicetopiperazina microcristalina
|
US9925144B2
(en)
|
2013-07-18 |
2018-03-27 |
Mannkind Corporation |
Heat-stable dry powder pharmaceutical compositions and methods
|
EP3030294B1
(de)
|
2013-08-05 |
2020-10-07 |
MannKind Corporation |
Insufflationsvorrichtung
|
US10307464B2
(en)
|
2014-03-28 |
2019-06-04 |
Mannkind Corporation |
Use of ultrarapid acting insulin
|
US10561806B2
(en)
|
2014-10-02 |
2020-02-18 |
Mannkind Corporation |
Mouthpiece cover for an inhaler
|
CN108310797A
(zh)
*
|
2018-04-09 |
2018-07-24 |
南通市华安超临界萃取有限公司 |
一种超临界流体重结晶装置
|
EP4065086A1
(de)
|
2019-11-25 |
2022-10-05 |
Regeneron Pharmaceuticals, Inc. |
Formulierungen mit verzögerter freisetzung unter verwendung nichtwässriger emulsionen
|
US20220160828A1
(en)
|
2020-11-25 |
2022-05-26 |
Regeneron Pharmaceuticals, Inc. |
Sustained release formulations using non-aqueous membrane emulsification
|
CA3205135A1
(en)
|
2020-12-17 |
2022-06-23 |
Regeneron Pharmaceuticals, Inc. |
Fabrication of protein-encapsulating microgels
|