DE69727221D1 - Technik zur epilepsiebehandlung durch hirnzellenanregung und medikamenteninfusion - Google Patents

Technik zur epilepsiebehandlung durch hirnzellenanregung und medikamenteninfusion

Info

Publication number
DE69727221D1
DE69727221D1 DE69727221T DE69727221T DE69727221D1 DE 69727221 D1 DE69727221 D1 DE 69727221D1 DE 69727221 T DE69727221 T DE 69727221T DE 69727221 T DE69727221 T DE 69727221T DE 69727221 D1 DE69727221 D1 DE 69727221D1
Authority
DE
Germany
Prior art keywords
technology
brain cell
medicine infusion
epilepsy treatment
cell excitation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69727221T
Other languages
English (en)
Other versions
DE69727221T2 (de
Inventor
Scott Ward
T Rise
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Inc
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Publication of DE69727221D1 publication Critical patent/DE69727221D1/de
Application granted granted Critical
Publication of DE69727221T2 publication Critical patent/DE69727221T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0693—Brain, cerebrum

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Electrotherapy Devices (AREA)
DE69727221T 1996-05-13 1997-04-28 Technik zur epilepsiebehandlung durch hirnzellenanregung und medikamenteninfusion Expired - Lifetime DE69727221T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US647590 1991-01-29
US08/647,590 US5713923A (en) 1996-05-13 1996-05-13 Techniques for treating epilepsy by brain stimulation and drug infusion
PCT/US1997/007115 WO1997042990A1 (en) 1996-05-13 1997-04-28 Techniques for treating epilepsy by brain stimulation and drug infusion

Publications (2)

Publication Number Publication Date
DE69727221D1 true DE69727221D1 (de) 2004-02-19
DE69727221T2 DE69727221T2 (de) 2004-11-04

Family

ID=24597559

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69727221T Expired - Lifetime DE69727221T2 (de) 1996-05-13 1997-04-28 Technik zur epilepsiebehandlung durch hirnzellenanregung und medikamenteninfusion

Country Status (5)

Country Link
US (2) US5713923A (de)
EP (1) EP0904119B1 (de)
AU (1) AU2746897A (de)
DE (1) DE69727221T2 (de)
WO (1) WO1997042990A1 (de)

Families Citing this family (300)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US20020169485A1 (en) 1995-10-16 2002-11-14 Neuropace, Inc. Differential neurostimulation therapy driven by physiological context
US6944501B1 (en) * 2000-04-05 2005-09-13 Neurospace, Inc. Neurostimulator involving stimulation strategies and process for using it
US6094598A (en) * 1996-04-25 2000-07-25 Medtronics, Inc. Method of treating movement disorders by brain stimulation and drug infusion
US5713923A (en) * 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion
US6647296B2 (en) * 1997-10-27 2003-11-11 Neuropace, Inc. Implantable apparatus for treating neurological disorders
US6354299B1 (en) * 1997-10-27 2002-03-12 Neuropace, Inc. Implantable device for patient communication
US6227203B1 (en) * 1998-02-12 2001-05-08 Medtronic, Inc. Techniques for controlling abnormal involuntary movements by brain stimulation and drug infusion
US6319241B1 (en) 1998-04-30 2001-11-20 Medtronic, Inc. Techniques for positioning therapy delivery elements within a spinal cord or a brain
US6018682A (en) * 1998-04-30 2000-01-25 Medtronic, Inc. Implantable seizure warning system
US6374140B1 (en) * 1998-04-30 2002-04-16 Medtronic, Inc. Method and apparatus for treating seizure disorders by stimulating the olfactory senses
US6161047A (en) 1998-04-30 2000-12-12 Medtronic Inc. Apparatus and method for expanding a stimulation lead body in situ
US5928272A (en) 1998-05-02 1999-07-27 Cyberonics, Inc. Automatic activation of a neurostimulator device using a detection algorithm based on cardiac activity
US7231254B2 (en) * 1998-08-05 2007-06-12 Bioneuronics Corporation Closed-loop feedback-driven neuromodulation
US9113801B2 (en) * 1998-08-05 2015-08-25 Cyberonics, Inc. Methods and systems for continuous EEG monitoring
US7403820B2 (en) * 1998-08-05 2008-07-22 Neurovista Corporation Closed-loop feedback-driven neuromodulation
US7277758B2 (en) * 1998-08-05 2007-10-02 Neurovista Corporation Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder
US8762065B2 (en) * 1998-08-05 2014-06-24 Cyberonics, Inc. Closed-loop feedback-driven neuromodulation
US7974696B1 (en) 1998-08-05 2011-07-05 Dilorenzo Biomedical, Llc Closed-loop autonomic neuromodulation for optimal control of neurological and metabolic disease
US9375573B2 (en) 1998-08-05 2016-06-28 Cyberonics, Inc. Systems and methods for monitoring a patient's neurological disease state
US9042988B2 (en) 1998-08-05 2015-05-26 Cyberonics, Inc. Closed-loop vagus nerve stimulation
US7209787B2 (en) * 1998-08-05 2007-04-24 Bioneuronics Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US7747325B2 (en) * 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US9415222B2 (en) 1998-08-05 2016-08-16 Cyberonics, Inc. Monitoring an epilepsy disease state with a supervisory module
AU5900299A (en) 1998-08-24 2000-03-14 Emory University Method and apparatus for predicting the onset of seizures based on features derived from signals indicative of brain activity
US6253109B1 (en) * 1998-11-05 2001-06-26 Medtronic Inc. System for optimized brain stimulation
US6161044A (en) * 1998-11-23 2000-12-12 Synaptic Corporation Method and apparatus for treating chronic pain syndromes, tremor, dementia and related disorders and for inducing electroanesthesia using high frequency, high intensity transcutaneous electrical nerve stimulation
US6923784B2 (en) 1999-04-30 2005-08-02 Medtronic, Inc. Therapeutic treatment of disorders based on timing information
US6341236B1 (en) * 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6669663B1 (en) * 1999-04-30 2003-12-30 Medtronic, Inc. Closed loop medicament pump
US6350253B1 (en) * 1999-07-19 2002-02-26 I-Flow Corporation Catheter for uniform delivery of medication
AU6465400A (en) 1999-08-04 2001-03-05 Impulse Dynamics N.V. Inhibition of action potentials
US7228171B2 (en) * 1999-10-19 2007-06-05 The Johns Hopkins University Signal analysis, heat flow management, and stimulation techniques to treat medical disorders
US6882881B1 (en) * 1999-10-19 2005-04-19 The Johns Hopkins University Techniques using heat flow management, stimulation, and signal analysis to treat medical disorders
US6876991B1 (en) 1999-11-08 2005-04-05 Collaborative Decision Platforms, Llc. System, method and computer program product for a collaborative decision platform
US6873872B2 (en) * 1999-12-07 2005-03-29 George Mason University Adaptive electric field modulation of neural systems
TW483768B (en) 1999-12-07 2002-04-21 George Mason Universityi Adaptive electric field modulation of neural systems
US6587733B1 (en) * 2000-02-08 2003-07-01 Medtronic, Inc. Percutaneous surgical lead body with directed stimulation
US20050055064A1 (en) * 2000-02-15 2005-03-10 Meadows Paul M. Open loop deep brain stimulation system for the treatment of Parkinson's Disease or other disorders
US6609030B1 (en) * 2000-02-24 2003-08-19 Electrocore Techniques, Llc Method of treating psychiatric diseases by neuromodulation within the dorsomedial thalamus
US6473639B1 (en) 2000-03-02 2002-10-29 Neuropace, Inc. Neurological event detection procedure using processed display channel based algorithms and devices incorporating these procedures
US6477427B1 (en) 2000-03-31 2002-11-05 Medtronic Inc. Implantable stimulation lead and method of manufacture
US6466822B1 (en) 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US6626902B1 (en) * 2000-04-12 2003-09-30 University Of Virginia Patent Foundation Multi-probe system
US20040073099A1 (en) * 2000-04-28 2004-04-15 Medtronic, Inc. Brain fluid ion concentration modification for treating neurological disorders
US6447500B1 (en) * 2000-04-28 2002-09-10 Medtronic, Inc. Brain fluid ion concentration modification for treating neurological disorders
US6592519B1 (en) 2000-04-28 2003-07-15 Medtronic, Inc. Smart microfluidic device with universal coating
US6306403B1 (en) * 2000-06-14 2001-10-23 Allergan Sales, Inc. Method for treating parkinson's disease with a botulinum toxin
US20090209831A1 (en) * 2000-06-28 2009-08-20 Nexgen Medical Systems, Incorporated Imaging methods for visualizing implanted living cells
US20030125786A1 (en) * 2000-07-13 2003-07-03 Gliner Bradford Evan Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7672730B2 (en) 2001-03-08 2010-03-02 Advanced Neuromodulation Systems, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7010351B2 (en) * 2000-07-13 2006-03-07 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7305268B2 (en) 2000-07-13 2007-12-04 Northstar Neurscience, Inc. Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators
US7236831B2 (en) 2000-07-13 2007-06-26 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7024247B2 (en) 2001-10-15 2006-04-04 Northstar Neuroscience, Inc. Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures
US7831305B2 (en) 2001-10-15 2010-11-09 Advanced Neuromodulation Systems, Inc. Neural stimulation system and method responsive to collateral neural activity
US7146217B2 (en) * 2000-07-13 2006-12-05 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a change in a neural-function of a patient
US20040176831A1 (en) * 2000-07-13 2004-09-09 Gliner Bradford Evan Apparatuses and systems for applying electrical stimulation to a patient
US20050021118A1 (en) * 2000-07-13 2005-01-27 Chris Genau Apparatuses and systems for applying electrical stimulation to a patient
US7756584B2 (en) * 2000-07-13 2010-07-13 Advanced Neuromodulation Systems, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US6497699B1 (en) * 2000-08-09 2002-12-24 The Research Foundation Of State University Of New York Hybrid neuroprosthesis for the treatment of brain disorders
US6591138B1 (en) 2000-08-31 2003-07-08 Neuropace, Inc. Low frequency neurostimulator for the treatment of neurological disorders
US6405079B1 (en) * 2000-09-22 2002-06-11 Mehdi M. Ansarinia Stimulation method for the dural venous sinuses and adjacent dura for treatment of medical conditions
US20040034321A1 (en) * 2000-10-05 2004-02-19 Seacoast Technologies, Inc. Conformal pad for neurosurgery and method thereof
CA2425061A1 (en) 2000-10-05 2002-04-11 Seacoast Technologies, Inc. Neurosurgical device for thermal therapy
US6678548B1 (en) 2000-10-20 2004-01-13 The Trustees Of The University Of Pennsylvania Unified probabilistic framework for predicting and detecting seizure onsets in the brain and multitherapeutic device
US6529774B1 (en) 2000-11-09 2003-03-04 Neuropace, Inc. Extradural leads, neurostimulator assemblies, and processes of using them for somatosensory and brain stimulation
US6594524B2 (en) 2000-12-12 2003-07-15 The Trustees Of The University Of Pennsylvania Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control
US7299096B2 (en) * 2001-03-08 2007-11-20 Northstar Neuroscience, Inc. System and method for treating Parkinson's Disease and other movement disorders
US6671555B2 (en) 2001-04-27 2003-12-30 Medtronic, Inc. Closed loop neuromodulation for suppression of epileptic activity
US20030040479A1 (en) * 2001-07-02 2003-02-27 Omeros Corporation Rotational intrathecal analgesia method and device
WO2003004034A1 (en) * 2001-07-02 2003-01-16 Omeros Corporation Method for inducing analgesia comprising administration alternatively of an opioid receptor agonist and an opioid receptor like receptor 1 agonist for and an implantable infusion pump
US7013177B1 (en) 2001-07-05 2006-03-14 Advanced Bionics Corporation Treatment of pain by brain stimulation
US6606521B2 (en) 2001-07-09 2003-08-12 Neuropace, Inc. Implantable medical lead
US6974448B2 (en) * 2001-08-30 2005-12-13 Medtronic, Inc. Method for convection enhanced delivery catheter to treat brain and other tumors
US6893429B2 (en) * 2001-08-30 2005-05-17 Medtronic, Inc. Convection enhanced delivery catheter to treat brain and other tumors
AU2002334749A1 (en) * 2001-09-28 2003-04-07 Northstar Neuroscience, Inc. Methods and implantable apparatus for electrical therapy
US20070088335A1 (en) * 2001-10-24 2007-04-19 Med-El Elektromedizinische Geraete Gmbh Implantable neuro-stimulation electrode with fluid reservoir
US6944497B2 (en) * 2001-10-31 2005-09-13 Medtronic, Inc. System and method of treating stuttering by neuromodulation
US20030105409A1 (en) 2001-11-14 2003-06-05 Donoghue John Philip Neurological signal decoding
US20030125662A1 (en) * 2002-01-03 2003-07-03 Tuan Bui Method and apparatus for providing medical treatment therapy based on calculated demand
US7108680B2 (en) * 2002-03-06 2006-09-19 Codman & Shurtleff, Inc. Closed-loop drug delivery system
US20030171738A1 (en) * 2002-03-06 2003-09-11 Konieczynski David D. Convection-enhanced drug delivery device and method of use
US7221981B2 (en) * 2002-03-28 2007-05-22 Northstar Neuroscience, Inc. Electrode geometries for efficient neural stimulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7003352B1 (en) 2002-05-24 2006-02-21 Advanced Bionics Corporation Treatment of epilepsy by brain stimulation
EP1513584A2 (de) * 2002-06-04 2005-03-16 Cyberkinetics, Inc. Optisch verbundene implantate, darauf bezogene systeme und deren verwendung
US20040049121A1 (en) 2002-09-06 2004-03-11 Uri Yaron Positioning system for neurological procedures in the brain
US20050075679A1 (en) * 2002-09-30 2005-04-07 Gliner Bradford E. Methods and apparatuses for treating neurological disorders by electrically stimulating cells implanted in the nervous system
WO2004034997A2 (en) * 2002-10-15 2004-04-29 Medtronic Inc. Medical device system with relaying module for treatment of nervous system disorders
AU2003301481A1 (en) * 2002-10-15 2004-05-04 Medtronic Inc. Channel-selective blanking for a medical device system
US8738136B2 (en) * 2002-10-15 2014-05-27 Medtronic, Inc. Clustering of recorded patient neurological activity to determine length of a neurological event
WO2004036376A2 (en) * 2002-10-15 2004-04-29 Medtronic Inc. Multi-modal operation of a medical device system
EP1558131A4 (de) * 2002-10-15 2008-05-28 Medtronic Inc VERZöGERUNG DER ERNEUTEN VERABREICHUNG EINER BEHANDLUNG FüR EIN MEDIZINISCHES VORRICHTUNGSSYSTEM
AU2003301255A1 (en) * 2002-10-15 2004-05-04 Medtronic Inc. Screening techniques for management of a nervous system disorder
AU2003278006A1 (en) * 2002-10-15 2004-05-04 Creo Inc. Automated information management system and methods
WO2004034982A2 (en) * 2002-10-15 2004-04-29 Medtronic Inc. Treatment termination in a medical device
ATE537748T1 (de) * 2002-10-15 2012-01-15 Medtronic Inc Medizinisches vorrichtungssystem zur bewertung von gemessenen neurologischen ereignissen
EP1562674A4 (de) * 2002-10-15 2008-10-08 Medtronic Inc Kontrolle der behandlung bei beginn und im betrieb einesmedizinischen vorrichtungssystems
WO2004036377A2 (en) * 2002-10-15 2004-04-29 Medtronic Inc. Configuring and testing treatment therapy parameters for a medical device system
EP1565102A4 (de) * 2002-10-15 2008-05-28 Medtronic Inc Synchronisation und kalibrierung von uhren für einmedizinprodukt und kalibrierte uhr
US7149572B2 (en) * 2002-10-15 2006-12-12 Medtronic, Inc. Phase shifting of neurological signals in a medical device system
WO2004034885A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Signal quality monitoring and control for a medical device system
US20050010261A1 (en) * 2002-10-21 2005-01-13 The Cleveland Clinic Foundation Application of stimulus to white matter to induce a desired physiological response
US20050049649A1 (en) * 2002-10-21 2005-03-03 The Cleveland Clinic Foundation Electrical stimulation of the brain
US7212851B2 (en) * 2002-10-24 2007-05-01 Brown University Research Foundation Microstructured arrays for cortex interaction and related methods of manufacture and use
US7236830B2 (en) * 2002-12-10 2007-06-26 Northstar Neuroscience, Inc. Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders
US7561919B2 (en) 2002-11-14 2009-07-14 Brainsgate Ltd. SPG stimulation via the greater palatine canal
US20050075680A1 (en) * 2003-04-18 2005-04-07 Lowry David Warren Methods and systems for intracranial neurostimulation and/or sensing
US7302298B2 (en) * 2002-11-27 2007-11-27 Northstar Neuroscience, Inc Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography
AU2003297761A1 (en) * 2002-12-09 2004-06-30 Northstar Neuroscience, Inc. Methods for treating neurological language disorders
US6959215B2 (en) * 2002-12-09 2005-10-25 Northstar Neuroscience, Inc. Methods for treating essential tremor
US8246602B2 (en) * 2002-12-23 2012-08-21 Medtronic, Inc. Catheters with tracking elements and permeable membranes
US8043281B2 (en) * 2002-12-23 2011-10-25 Medtronic, Inc. Catheters incorporating valves and permeable membranes
EP1581287A1 (de) * 2002-12-23 2005-10-05 Medtronic, Inc. Katheter mit mehreren infusionsabschnitten und zugehörige methoden
US6902544B2 (en) * 2003-01-22 2005-06-07 Codman & Shurtleff, Inc. Troubleshooting accelerator system for implantable drug delivery pumps
US7155279B2 (en) * 2003-03-28 2006-12-26 Advanced Bionics Corporation Treatment of movement disorders with drug therapy
US9446229B2 (en) 2003-04-08 2016-09-20 Omar Omar-Pasha Catheter
DE10318071A1 (de) * 2003-04-17 2004-11-25 Forschungszentrum Jülich GmbH Vorrichtung zur Desynchronisation von neuronaler Hirnaktivität
US6990377B2 (en) 2003-04-24 2006-01-24 Northstar Neuroscience, Inc. Systems and methods for facilitating and/or effectuating development, rehabilitation, restoration, and/or recovery of visual function through neural stimulation
US7149574B2 (en) * 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
US7738952B2 (en) * 2003-06-09 2010-06-15 Palo Alto Investors Treatment of conditions through modulation of the autonomic nervous system
CA2432810A1 (en) * 2003-06-19 2004-12-19 Andres M. Lozano Method of treating depression, mood disorders and anxiety disorders by brian infusion
US20050004221A1 (en) * 2003-07-01 2005-01-06 Medtronic, Inc. Intrathecal gabapentin compositions
US20050004219A1 (en) * 2003-07-01 2005-01-06 Medtronic, Inc. Pump systems including injectable gabapentin compositions
EP1654032A2 (de) * 2003-08-01 2006-05-10 Northstar Neuroscience, Inc. Gerät und verfahren für die neurale stimulation eines patienten
US20050153885A1 (en) * 2003-10-08 2005-07-14 Yun Anthony J. Treatment of conditions through modulation of the autonomic nervous system
US20050143378A1 (en) 2003-12-29 2005-06-30 Yun Anthony J. Treatment of conditions through pharmacological modulation of the autonomic nervous system
US20050090548A1 (en) * 2003-10-23 2005-04-28 Medtronic, Inc. Intrathecal gabapentin for treatment of epilepsy
US7022116B2 (en) * 2003-10-23 2006-04-04 Medtronic, Inc. Method for monitoring bolus delivery
US20050090549A1 (en) * 2003-10-23 2005-04-28 Medtronic, Inc. Intrathecal gabapentin for treatment of pain
EP1677667A2 (de) * 2003-10-24 2006-07-12 Medtronic, Inc. Techniken zur behandlung von neurologischen erkrankungen durch abschwächung der produktion von entzündungsfördernden mediatoren
US8617572B2 (en) 2003-10-29 2013-12-31 Allergan, Inc. Botulinum toxin treatments of depression
US8734810B2 (en) 2003-10-29 2014-05-27 Allergan, Inc. Botulinum toxin treatments of neurological and neuropsychiatric disorders
US8609112B2 (en) 2003-10-29 2013-12-17 Allergan, Inc. Botulinum toxin treatments of depression
US8609113B2 (en) 2003-10-29 2013-12-17 Allergan, Inc. Botulinum toxin treatments of depression
US20050143589A1 (en) * 2003-11-09 2005-06-30 Donoghue John P. Calibration systems and methods for neural interface devices
US20050113744A1 (en) * 2003-11-21 2005-05-26 Cyberkinetics, Inc. Agent delivery systems and related methods under control of biological electrical signals
US7751877B2 (en) * 2003-11-25 2010-07-06 Braingate Co., Llc Neural interface system with embedded id
US9050469B1 (en) 2003-11-26 2015-06-09 Flint Hills Scientific, Llc Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
US20050137579A1 (en) * 2003-12-23 2005-06-23 Medtronic, Inc. Permeable membrane catheters, systems, and methods
US7846137B2 (en) * 2003-12-26 2010-12-07 Medtronic Minimed, Inc. Modular catheter system
US7226430B2 (en) * 2003-12-26 2007-06-05 Codman & Shurtleff, Inc. Closed loop system and method for controlling muscle activity via an intrathecal catheter
US7676269B2 (en) * 2003-12-29 2010-03-09 Palo Alto Investors Treatment of female fertility conditions through modulation of the autonomic nervous system
US7647097B2 (en) * 2003-12-29 2010-01-12 Braingate Co., Llc Transcutaneous implant
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US20050203366A1 (en) * 2004-03-12 2005-09-15 Donoghue John P. Neurological event monitoring and therapy systems and related methods
US7717848B2 (en) 2004-03-16 2010-05-18 Medtronic, Inc. Collecting sleep quality information via a medical device
US8725244B2 (en) 2004-03-16 2014-05-13 Medtronic, Inc. Determination of sleep quality for neurological disorders
US7366572B2 (en) 2004-03-16 2008-04-29 Medtronic, Inc. Controlling therapy based on sleep quality
US8055348B2 (en) 2004-03-16 2011-11-08 Medtronic, Inc. Detecting sleep to evaluate therapy
WO2005107858A1 (en) * 2004-04-30 2005-11-17 Advanced Neuromodulation Systems, Inc. Method of treating mood disorders and/or anxiety disorders by brain stimulation
US20100260669A1 (en) * 2004-05-13 2010-10-14 Anthony Joonkyoo Yun Treatment of Seasonal Conditions Through Modulation of the Autonomic Nervous System
US7899527B2 (en) * 2004-05-13 2011-03-01 Palo Alto Investors Treatment of conditions through modulation of the autonomic nervous system during at least one predetermined menstrual cycle phase
DE102004025825A1 (de) * 2004-05-24 2005-12-29 Forschungszentrum Jülich GmbH Vorrichtung zur Behandlung von Patienten mittels Hirnstimulation, ein elektronisches Bauteil sowie die Verwendung der Vorrichtung und des elektronischen Bauteils in der Medizin und medizinisches Behandlungsverfahren
EP1786510A4 (de) 2004-07-15 2009-12-02 Northstar Neuroscience Inc Systeme und verfahren zur verstärkung oder beeinflussung der effizienz oder wirksamkeit einer neuralen stimulation
EP1786320B1 (de) * 2004-07-27 2016-09-14 MRI Interventions, Inc. Mri-systeme mit mri-kompatiblen universellen ablieferungskanülen mit kooperierenden mri-antennensonden und diesbezügliche systeme und verfahren
EP1799302B1 (de) * 2004-07-28 2015-03-04 Ardian, Inc. Vorrichtungen für die nierennervenblockade
US8569277B2 (en) * 2004-08-11 2013-10-29 Palo Alto Investors Methods of treating a subject for a condition
US20060049957A1 (en) * 2004-08-13 2006-03-09 Surgenor Timothy R Biological interface systems with controlled device selector and related methods
US8560041B2 (en) * 2004-10-04 2013-10-15 Braingate Co., Llc Biological interface system
US8473060B2 (en) * 2004-10-05 2013-06-25 The Trustees Of Dartmouth College Apparatus and method for modulating neurochemical levels in the brain
WO2006041871A2 (en) * 2004-10-05 2006-04-20 Dartmouth College Apparatus and method for modulating neurochemical levels in the brain
US20060253100A1 (en) 2004-10-22 2006-11-09 Medtronic, Inc. Systems and Methods to Treat Pain Locally
US20060106430A1 (en) * 2004-11-12 2006-05-18 Brad Fowler Electrode configurations for reducing invasiveness and/or enhancing neural stimulation efficacy, and associated methods
US7565200B2 (en) * 2004-11-12 2009-07-21 Advanced Neuromodulation Systems, Inc. Systems and methods for selecting stimulation sites and applying treatment, including treatment of symptoms of Parkinson's disease, other movement disorders, and/or drug side effects
CN101076290B (zh) 2004-12-09 2011-11-23 铸造品股份有限公司 主动脉瓣修复
US7366571B2 (en) 2004-12-10 2008-04-29 Cyberonics, Inc. Neurostimulator with activation based on changes in body temperature
US8108038B2 (en) * 2004-12-17 2012-01-31 Medtronic, Inc. System and method for segmenting a cardiac signal based on brain activity
US8214035B2 (en) 2004-12-17 2012-07-03 Medtronic, Inc. System and method for utilizing brain state information to modulate cardiac therapy
US20070239060A1 (en) * 2004-12-17 2007-10-11 Medtronic, Inc. System and method for regulating cardiac triggered therapy to the brain
US8209019B2 (en) * 2004-12-17 2012-06-26 Medtronic, Inc. System and method for utilizing brain state information to modulate cardiac therapy
ATE527016T1 (de) * 2004-12-17 2011-10-15 Medtronic Inc System zur überwachung oder behandlung von erkrankungen des nervensystems
US8485979B2 (en) * 2004-12-17 2013-07-16 Medtronic, Inc. System and method for monitoring or treating nervous system disorders
US8112153B2 (en) * 2004-12-17 2012-02-07 Medtronic, Inc. System and method for monitoring or treating nervous system disorders
US8112148B2 (en) * 2004-12-17 2012-02-07 Medtronic, Inc. System and method for monitoring cardiac signal activity in patients with nervous system disorders
US8108046B2 (en) 2004-12-17 2012-01-31 Medtronic, Inc. System and method for using cardiac events to trigger therapy for treating nervous system disorders
US8209009B2 (en) * 2004-12-17 2012-06-26 Medtronic, Inc. System and method for segmenting a cardiac signal based on brain stimulation
US8095209B2 (en) * 2005-01-06 2012-01-10 Braingate Co., Llc Biological interface system with gated control signal
US7901368B2 (en) * 2005-01-06 2011-03-08 Braingate Co., Llc Neurally controlled patient ambulation system
US20070032738A1 (en) * 2005-01-06 2007-02-08 Flaherty J C Adaptive patient training routine for biological interface system
US20060189899A1 (en) * 2005-01-10 2006-08-24 Flaherty J Christopher Joint movement apparatus
US20060189901A1 (en) * 2005-01-10 2006-08-24 Flaherty J C Biological interface system with surrogate controlled device
DE202005000544U1 (de) * 2005-01-13 2006-05-24 Mantsch, Christian Medizinisches Elektrodensystem
US8060194B2 (en) * 2005-01-18 2011-11-15 Braingate Co., Llc Biological interface system with automated configuration
US8600521B2 (en) * 2005-01-27 2013-12-03 Cyberonics, Inc. Implantable medical device having multiple electrode/sensor capability and stimulation based on sensed intrinsic activity
US7561918B2 (en) 2005-01-28 2009-07-14 Cyberonics, Inc. Autocapture in a neurostimulator
US7454245B2 (en) 2005-01-28 2008-11-18 Cyberonics, Inc. Trained and adaptive response in a neurostimulator
US9931500B2 (en) * 2005-03-01 2018-04-03 Andres M. Lozano Method of treating depression, mood disorders and anxiety disorders using neuromodulation
WO2006094072A2 (en) * 2005-03-01 2006-09-08 Functional Neuroscience Inc. Method of treating cognitive disorders using neuromodulation
US20070027499A1 (en) * 2005-07-29 2007-02-01 Cyberonics, Inc. Neurostimulation device for treating mood disorders
US7499752B2 (en) * 2005-07-29 2009-03-03 Cyberonics, Inc. Selective nerve stimulation for the treatment of eating disorders
US20070055320A1 (en) * 2005-09-07 2007-03-08 Northstar Neuroscience, Inc. Methods for treating temporal lobe epilepsy, associated neurological disorders, and other patient functions
US20070088404A1 (en) * 2005-10-19 2007-04-19 Allen Wyler Methods and systems for improving neural functioning, including cognitive functioning and neglect disorders
US7856264B2 (en) * 2005-10-19 2010-12-21 Advanced Neuromodulation Systems, Inc. Systems and methods for patient interactive neural stimulation and/or chemical substance delivery
US7729773B2 (en) 2005-10-19 2010-06-01 Advanced Neuromodualation Systems, Inc. Neural stimulation and optical monitoring systems and methods
US8929991B2 (en) 2005-10-19 2015-01-06 Advanced Neuromodulation Systems, Inc. Methods for establishing parameters for neural stimulation, including via performance of working memory tasks, and associated kits
US7555344B2 (en) * 2005-10-28 2009-06-30 Cyberonics, Inc. Selective neurostimulation for treating epilepsy
US20070106143A1 (en) * 2005-11-08 2007-05-10 Flaherty J C Electrode arrays and related methods
WO2007075477A2 (en) * 2005-12-19 2007-07-05 University Of Florida Closed-loop state-dependent seizure prevention systems
US20100023021A1 (en) * 2005-12-27 2010-01-28 Flaherty J Christopher Biological Interface and Insertion
US20070156126A1 (en) * 2005-12-29 2007-07-05 Flaherty J C Medical device insertion system and related methods
US20070149952A1 (en) * 2005-12-28 2007-06-28 Mike Bland Systems and methods for characterizing a patient's propensity for a neurological event and for communicating with a pharmacological agent dispenser
US8868172B2 (en) * 2005-12-28 2014-10-21 Cyberonics, Inc. Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US8725243B2 (en) * 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US7657310B2 (en) 2006-01-26 2010-02-02 Cyberonics, Inc. Treatment of reproductive endocrine disorders by vagus nerve stimulation
US7801601B2 (en) 2006-01-27 2010-09-21 Cyberonics, Inc. Controlling neuromodulation using stimulus modalities
US20070287931A1 (en) * 2006-02-14 2007-12-13 Dilorenzo Daniel J Methods and systems for administering an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
EP1998849B1 (de) 2006-03-24 2014-12-24 Medtronic, Inc. Sammlung von ganginformationen zur beurteilung und kontrolle einer therapie
US8326431B2 (en) * 2006-04-28 2012-12-04 Medtronic, Inc. Implantable medical device for the concurrent treatment of a plurality of neurological disorders and method therefore
US20080027348A1 (en) * 2006-06-23 2008-01-31 Neuro Vista Corporation Minimally Invasive Monitoring Systems for Monitoring a Patient's Propensity for a Neurological Event
US8025634B1 (en) * 2006-09-18 2011-09-27 Baxter International Inc. Method and system for controlled infusion of therapeutic substances
US8295934B2 (en) * 2006-11-14 2012-10-23 Neurovista Corporation Systems and methods of reducing artifact in neurological stimulation systems
US20080161712A1 (en) * 2006-12-27 2008-07-03 Kent Leyde Low Power Device With Contingent Scheduling
US7706875B2 (en) 2007-01-25 2010-04-27 Cyberonics, Inc. Modulation of drug effects by vagus nerve stimulation
WO2008092133A2 (en) * 2007-01-25 2008-07-31 Neurovista Corporation Methods and systems for measuring a subject's susceptibility to a seizure
US9898656B2 (en) 2007-01-25 2018-02-20 Cyberonics, Inc. Systems and methods for identifying a contra-ictal condition in a subject
US20080208074A1 (en) * 2007-02-21 2008-08-28 David Snyder Methods and Systems for Characterizing and Generating a Patient-Specific Seizure Advisory System
US8036736B2 (en) 2007-03-21 2011-10-11 Neuro Vista Corporation Implantable systems and methods for identifying a contra-ictal condition in a subject
US20080249591A1 (en) * 2007-04-06 2008-10-09 Northstar Neuroscience, Inc. Controllers for implantable medical devices, and associated methods
US7611483B2 (en) 2007-04-19 2009-11-03 Medtronic, Inc. Indicator metrics for infection monitoring
US8000788B2 (en) * 2007-04-27 2011-08-16 Medtronic, Inc. Implantable medical device for treating neurological conditions including ECG sensing
US7556373B2 (en) * 2007-07-13 2009-07-07 Nike, Inc. Eyewear with retaining assembly
US20090030403A1 (en) * 2007-07-27 2009-01-29 Leyde Kent W Methods and Systems for Attenuating the Tolerance Response to a Drug
US9788744B2 (en) 2007-07-27 2017-10-17 Cyberonics, Inc. Systems for monitoring brain activity and patient advisory device
WO2009026382A1 (en) * 2007-08-20 2009-02-26 Kopell, Brian, H. Systems and methods for treating neurological disorders by light stimulation
WO2009055000A1 (en) 2007-10-23 2009-04-30 Optima Neuroscience, Inc. System for seizure monitoring and detection
EP2222700A2 (de) 2007-11-27 2010-09-01 Medtronic, Inc. Humanisierte anti-amyloid-beta-antikörper
WO2009073891A1 (en) * 2007-12-07 2009-06-11 Northstar Neuroscience, Inc. Systems and methods for providing targeted neural stimulation therapy to address neurological disorders, including neuropyschiatric and neuropyschological disorders
US9259591B2 (en) * 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US20090171168A1 (en) * 2007-12-28 2009-07-02 Leyde Kent W Systems and Method for Recording Clinical Manifestations of a Seizure
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
US8660651B2 (en) * 2008-06-30 2014-02-25 Accelerated Care Plus Corp. Electrical stimulation method for treatment of peripheral neuropathy
JP5653918B2 (ja) 2008-07-30 2015-01-14 エコーレ ポリテクニーク フェデラーレ デ ローザンヌ （イーピーエフエル） 神経標的の最適化された刺激のための装置および方法
US8417344B2 (en) 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
US20100121214A1 (en) 2008-11-11 2010-05-13 Medtronic, Inc. Seizure disorder evaluation based on intracranial pressure and patient motion
EP3563902B1 (de) 2008-11-12 2021-07-14 Ecole Polytechnique Fédérale de Lausanne Mikrohergestellte neurostimulationsvorrichtung
EP2369986A4 (de) * 2008-12-23 2013-08-28 Neurovista Corp Gehirnzustandsanalyse auf basis ausgewählter anfallausbruchseigenschaften und klinischer manifestationen
US8849390B2 (en) 2008-12-29 2014-09-30 Cyberonics, Inc. Processing for multi-channel signals
US8588933B2 (en) 2009-01-09 2013-11-19 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US8374703B2 (en) * 2009-01-26 2013-02-12 Incube Labs, Llc Method and apparatus for the detection of aberrant neural-electric activity
US9107993B2 (en) 2011-11-21 2015-08-18 Incube Labs, Llc Myocardial drug delivery apparatus and method
US11331424B2 (en) 2009-01-26 2022-05-17 Incube Labs, Llc Apparatus, systems and methods for delivery of medication to the brain to treat neurological conditions
US20100239632A1 (en) 2009-03-23 2010-09-23 Warsaw Orthopedic, Inc. Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US8239028B2 (en) 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
US8172759B2 (en) * 2009-04-24 2012-05-08 Cyberonics, Inc. Methods and systems for detecting epileptic events using nonlinear analysis parameters
US20100280336A1 (en) * 2009-04-30 2010-11-04 Medtronic, Inc. Anxiety disorder monitoring
US8786624B2 (en) 2009-06-02 2014-07-22 Cyberonics, Inc. Processing for multi-channel signals
WO2011000034A1 (en) * 2009-06-30 2011-01-06 The Bionic Ear Institute Method of counteracting seizures
CA2782710C (en) 2009-12-01 2019-01-22 Ecole Polytechnique Federale De Lausanne Microfabricated neurostimulation device and methods of making and using the same
US8914115B2 (en) * 2009-12-03 2014-12-16 Medtronic, Inc. Selecting therapy cycle parameters based on monitored brain signal
US9643019B2 (en) 2010-02-12 2017-05-09 Cyberonics, Inc. Neurological monitoring and alerts
US20110219325A1 (en) * 2010-03-02 2011-09-08 Himes David M Displaying and Manipulating Brain Function Data Including Enhanced Data Scrolling Functionality
US20110218820A1 (en) * 2010-03-02 2011-09-08 Himes David M Displaying and Manipulating Brain Function Data Including Filtering of Annotations
US9717439B2 (en) 2010-03-31 2017-08-01 Medtronic, Inc. Patient data display
JP5927176B2 (ja) 2010-04-01 2016-06-01 エコーレ ポリテクニーク フェデラーレ デ ローザンヌ （イーピーエフエル） 神経組織と相互作用するためのデバイス、ならびにそれを作製および使用する方法
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
WO2011149461A1 (en) 2010-05-27 2011-12-01 Medtronic, Inc. Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
US9950112B2 (en) * 2010-08-17 2018-04-24 University Of Florida Research Foundation, Incorporated Intelligent drug and/or fluid delivery system to optimizing medical treatment or therapy using pharmacodynamic and/or pharamacokinetic data
WO2012050847A2 (en) 2010-09-28 2012-04-19 Masimo Corporation Depth of consciousness monitor including oximeter
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
WO2012103224A1 (en) 2011-01-25 2012-08-02 Medtronic, Inc. Target therapy delivery site selection
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
EP2694150A1 (de) 2011-04-08 2014-02-12 Covidien LP Iontophorese-medikamentenabgabesystem sowie verfahren zur denervierung der renalen sympathischen nerven und iontophorese-medikamentenabgabe
US8725239B2 (en) 2011-04-25 2014-05-13 Cyberonics, Inc. Identifying seizures using heart rate decrease
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
US10206591B2 (en) 2011-10-14 2019-02-19 Flint Hills Scientific, Llc Seizure detection methods, apparatus, and systems using an autoregression algorithm
US10220144B2 (en) * 2011-11-21 2019-03-05 Incube Labs, Llc Apparatus, systems and methods for the treatment of neurological conditions
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
US10933218B2 (en) 2013-07-30 2021-03-02 Massachusetts Institute Of Technology Systems and methods for delivering chemical and electrical stimulation across one or more neural circuits
EP2878335B1 (de) 2013-11-10 2018-01-03 Brainsgate Ltd. Implantat und implantationssystem für nervenstimulator
US9192759B2 (en) 2014-03-31 2015-11-24 Dennison Hamilton System and method for stabilizing implanted spinal cord stimulators
EP3476430B1 (de) 2014-05-16 2020-07-01 Aleva Neurotherapeutics SA Vorrichtung zur interaktion mit neurologischem gewebe
US11311718B2 (en) 2014-05-16 2022-04-26 Aleva Neurotherapeutics Sa Device for interacting with neurological tissue and methods of making and using the same
US9403011B2 (en) 2014-08-27 2016-08-02 Aleva Neurotherapeutics Leadless neurostimulator
US9474894B2 (en) 2014-08-27 2016-10-25 Aleva Neurotherapeutics Deep brain stimulation lead
US10154815B2 (en) 2014-10-07 2018-12-18 Masimo Corporation Modular physiological sensors
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
EP3411111A1 (de) 2016-02-02 2018-12-12 Aleva Neurotherapeutics SA Behandlung von autoimmunkrankheiten mit tiefhirnstimulation
US11596795B2 (en) 2017-07-31 2023-03-07 Medtronic, Inc. Therapeutic electrical stimulation therapy for patient gait freeze
US11116561B2 (en) 2018-01-24 2021-09-14 Medtronic Ardian Luxembourg S.A.R.L. Devices, agents, and associated methods for selective modulation of renal nerves
US10702692B2 (en) 2018-03-02 2020-07-07 Aleva Neurotherapeutics Neurostimulation device
WO2020068830A1 (en) 2018-09-24 2020-04-02 Vivek Sharma Auricular nerve stimulation to address patient disorders, and associated systems and methods

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3850161A (en) * 1973-04-09 1974-11-26 S Liss Method and apparatus for monitoring and counteracting excess brain electrical energy to prevent epileptic seizures and the like
US3918461A (en) * 1974-01-31 1975-11-11 Irving S Cooper Method for electrically stimulating the human brain
US4146029A (en) * 1974-04-23 1979-03-27 Ellinwood Jr Everett H Self-powered implanted programmable medication system and method
US3993046A (en) * 1974-11-06 1976-11-23 Heriberto Fernandez Seizure suppression device
US4692147A (en) * 1980-04-02 1987-09-08 Medtronic, Inc. Drug administration device
WO1985001213A1 (en) * 1983-09-14 1985-03-28 Jacob Zabara Neurocybernetic prosthesis
US5025807A (en) * 1983-09-14 1991-06-25 Jacob Zabara Neurocybernetic prosthesis
US4867164A (en) * 1983-09-14 1989-09-19 Jacob Zabara Neurocybernetic prosthesis
US4702254A (en) * 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
JPS63115538A (ja) * 1986-11-04 1988-05-20 株式会社日本エム・デイ・エム 頭蓋内圧測定装置
US5871472A (en) * 1987-11-17 1999-02-16 Brown University Research Foundation Planting devices for the focal release of neuroinhibitory compounds
US5108363A (en) * 1988-02-19 1992-04-28 Gensia Pharmaceuticals, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
US5011472A (en) * 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
US5458631A (en) * 1989-01-06 1995-10-17 Xavier; Ravi Implantable catheter with electrical pulse nerve stimulators and drug delivery system
US5154172A (en) * 1989-11-13 1992-10-13 Cyberonics, Inc. Constant current sources with programmable voltage source
US5031618A (en) * 1990-03-07 1991-07-16 Medtronic, Inc. Position-responsive neuro stimulator
US5342410A (en) * 1990-10-05 1994-08-30 Eric Braverman Apparatus and method for increasing the amplitude of P300 waves in the human brain
US5269303A (en) * 1991-02-22 1993-12-14 Cyberonics, Inc. Treatment of dementia by nerve stimulation
US5299569A (en) * 1991-05-03 1994-04-05 Cyberonics, Inc. Treatment of neuropsychiatric disorders by nerve stimulation
US5293879A (en) * 1991-09-23 1994-03-15 Vitatron Medical, B.V. System an method for detecting tremors such as those which result from parkinson's disease
US5342401A (en) * 1992-08-19 1994-08-30 The Regents Of The University Of California Real time cardiac arrhythmia stabilizing system
DE69331185T2 (de) * 1993-03-26 2002-07-18 Edwards Lifesciences Corp Intra-cranialer Druckmonitor und Drainagekatheter
US5697975A (en) * 1994-02-09 1997-12-16 The University Of Iowa Research Foundation Human cerebral cortex neural prosthetic for tinnitus
US5540734A (en) * 1994-09-28 1996-07-30 Zabara; Jacob Cranial nerve stimulation treatments using neurocybernetic prosthesis
US5716377A (en) * 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5707396A (en) * 1996-04-25 1998-01-13 Institute National De La Sante De La Recherche Medicale (Inserm) Method of arresting degeneration of the substantia nigra by high frequency stimulation of subthalamic nucleus
US5683422A (en) * 1996-04-25 1997-11-04 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
US5711316A (en) * 1996-04-30 1998-01-27 Medtronic, Inc. Method of treating movement disorders by brain infusion
US5735814A (en) * 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
US5713923A (en) * 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion
US5752979A (en) * 1996-11-01 1998-05-19 Medtronic, Inc. Method of controlling epilepsy by brain stimulation
US5800474A (en) * 1996-11-01 1998-09-01 Medtronic, Inc. Method of controlling epilepsy by brain stimulation

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