DE69733664D1 - Verfahren zur INaktivierung von Viren und Lyophilisierung von Blutproteinen - Google Patents

Verfahren zur INaktivierung von Viren und Lyophilisierung von Blutproteinen

Info

Publication number
DE69733664D1
DE69733664D1 DE69733664T DE69733664T DE69733664D1 DE 69733664 D1 DE69733664 D1 DE 69733664D1 DE 69733664 T DE69733664 T DE 69733664T DE 69733664 T DE69733664 T DE 69733664T DE 69733664 D1 DE69733664 D1 DE 69733664D1
Authority
DE
Germany
Prior art keywords
factor viii
blood proteins
cyclodextrin
inactivating viruses
lyophilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69733664T
Other languages
English (en)
Other versions
DE69733664T2 (de
DE69733664T3 (de
Inventor
Prabir Bhattacharya
Toshiharu Motokubota
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grifols Shared Services North America Inc
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24545689&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69733664(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Publication of DE69733664D1 publication Critical patent/DE69733664D1/de
Publication of DE69733664T2 publication Critical patent/DE69733664T2/de
Application granted granted Critical
Publication of DE69733664T3 publication Critical patent/DE69733664T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/32—Extraction; Separation; Purification by precipitation as complexes
DE69733664T 1996-04-19 1997-04-17 Verfahren zur INaktivierung von Viren und Lyophilisierung von Blutproteinen Expired - Lifetime DE69733664T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63492196A 1996-04-19 1996-04-19
US634921 1996-04-19
PCT/US1997/006585 WO1997039761A1 (en) 1996-04-19 1997-04-17 A process for viral inactivation of lyophilized blood proteins

Publications (3)

Publication Number Publication Date
DE69733664D1 true DE69733664D1 (de) 2005-08-04
DE69733664T2 DE69733664T2 (de) 2005-12-15
DE69733664T3 DE69733664T3 (de) 2011-04-14

Family

ID=24545689

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69733664T Expired - Lifetime DE69733664T3 (de) 1996-04-19 1997-04-17 Verfahren zur INaktivierung von Viren und Lyophilisierung von Blutproteinen

Country Status (8)

Country Link
US (1) US6566504B2 (de)
EP (1) EP0954326B2 (de)
JP (1) JP2000509374A (de)
AT (1) ATE298582T1 (de)
CA (1) CA2252374C (de)
DE (1) DE69733664T3 (de)
ES (1) ES2243994T5 (de)
WO (1) WO1997039761A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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US8735374B2 (en) * 2009-07-31 2014-05-27 Intelgenx Corp. Oral mucoadhesive dosage form
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US7989593B1 (en) 2010-05-27 2011-08-02 Bing Lou Wong Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof
US7932356B1 (en) 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
US8048856B1 (en) 2010-06-23 2011-11-01 Billion King, Ltd. Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition
US8084581B1 (en) 2011-04-29 2011-12-27 Bing Lou Wong Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus
US20130052232A1 (en) 2011-08-31 2013-02-28 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking
AR107262A1 (es) * 2016-01-27 2018-04-11 Lilly Co Eli Inactivación de patógenos por delipidación
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー 凍結乾燥方法
JP2022525742A (ja) 2019-03-14 2022-05-19 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー 凍結乾燥用ローディングトレイ組立体及びシステム

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Also Published As

Publication number Publication date
CA2252374A1 (en) 1997-10-30
WO1997039761A1 (en) 1997-10-30
ES2243994T3 (es) 2005-12-01
CA2252374C (en) 2007-08-07
DE69733664T2 (de) 2005-12-15
JP2000509374A (ja) 2000-07-25
EP0954326B1 (de) 2005-06-29
EP0954326B2 (de) 2009-07-22
DE69733664T3 (de) 2011-04-14
ATE298582T1 (de) 2005-07-15
EP0954326A4 (de) 2002-11-20
EP0954326A1 (de) 1999-11-10
US6566504B2 (en) 2003-05-20
ES2243994T5 (es) 2009-10-29
US20010047085A1 (en) 2001-11-29

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: GRIFOLS INC., LOS ANGELES, CA, US

8327 Change in the person/name/address of the patent owner

Owner name: GRIFOLS INC. (N.D. GES.D.STAATES DELAWARE), LO, US