DE69738874D1 - Stabilisierte gasübersättigte emulsionen und suspensionen - Google Patents

Stabilisierte gasübersättigte emulsionen und suspensionen

Info

Publication number
DE69738874D1
DE69738874D1 DE69738874T DE69738874T DE69738874D1 DE 69738874 D1 DE69738874 D1 DE 69738874D1 DE 69738874 T DE69738874 T DE 69738874T DE 69738874 T DE69738874 T DE 69738874T DE 69738874 D1 DE69738874 D1 DE 69738874D1
Authority
DE
Germany
Prior art keywords
overhauled
emulsions
suspensions
stabilized gas
stabilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69738874T
Other languages
English (en)
Inventor
J Richard Spears
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wayne State University
Original Assignee
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wayne State University filed Critical Wayne State University
Application granted granted Critical
Publication of DE69738874D1 publication Critical patent/DE69738874D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69738874T 1996-10-11 1997-10-09 Stabilisierte gasübersättigte emulsionen und suspensionen Expired - Lifetime DE69738874D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/730,517 US5834519A (en) 1996-10-11 1996-10-11 Stabilized gas-supersaturated emulsions and suspensions
PCT/US1997/018594 WO1998016203A1 (en) 1996-10-11 1997-10-09 Stabilized gas-supersaturated emulsions and suspensions

Publications (1)

Publication Number Publication Date
DE69738874D1 true DE69738874D1 (de) 2008-09-11

Family

ID=24935684

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738874T Expired - Lifetime DE69738874D1 (de) 1996-10-11 1997-10-09 Stabilisierte gasübersättigte emulsionen und suspensionen

Country Status (8)

Country Link
US (7) US5834519A (de)
EP (1) EP0984771B1 (de)
JP (2) JP2001502335A (de)
AU (1) AU4757097A (de)
CA (1) CA2268405A1 (de)
DE (1) DE69738874D1 (de)
ES (1) ES2312176T3 (de)
WO (1) WO1998016203A1 (de)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676900B1 (en) 1994-12-09 2004-01-13 Therox, Inc. Method for the preparation and delivery of gas-enriched fluids
US6607698B1 (en) * 1997-08-15 2003-08-19 Therox, Inc. Method for generalized extracorporeal support
US6537246B1 (en) * 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US6386751B1 (en) 1997-10-24 2002-05-14 Diffusion Dynamics, Inc. Diffuser/emulsifier
US7654728B2 (en) * 1997-10-24 2010-02-02 Revalesio Corporation System and method for therapeutic application of dissolved oxygen
US7128278B2 (en) * 1997-10-24 2006-10-31 Microdiffusion, Inc. System and method for irritating with aerated water
US6702949B2 (en) 1997-10-24 2004-03-09 Microdiffusion, Inc. Diffuser/emulsifier for aquaculture applications
FI981407A (fi) * 1998-05-11 1999-11-12 Nokia Networks Oy Handover ja verkkosovitus radiojärjestelmässä
US6602467B1 (en) 1998-07-24 2003-08-05 Therox, Inc. Apparatus and method for blood oxygenation
US6576191B1 (en) 1999-09-30 2003-06-10 Therox, Inc. Apparatus for blood oxygenation
US6387324B1 (en) 1999-09-30 2002-05-14 Therox, Inc. Apparatus and method for blood oxygenation
US6759008B1 (en) 1999-09-30 2004-07-06 Therox, Inc. Apparatus and method for blood oxygenation
US6890482B2 (en) 1999-09-30 2005-05-10 Therox, Inc. Apparatus for blood oxygenation
CA2436427A1 (en) * 2001-02-01 2002-08-08 Hydron Technologies, Inc. Compositions and method of tissue superoxygenation
US6613280B2 (en) 2001-03-20 2003-09-02 Therox, Inc. Disposable cartridge for producing gas-enriched fluids
US6582387B2 (en) * 2001-03-20 2003-06-24 Therox, Inc. System for enriching a bodily fluid with a gas
US20120156309A1 (en) * 2007-09-19 2012-06-21 Eckert C Edward Using Aqueous Oxygenation to Improve Animal Health & Wellness
US20130041312A1 (en) * 2007-09-19 2013-02-14 C. Edward Eckert Using Aqueous Oxygenation to Improve Human Wellness
US7357937B2 (en) 2002-09-24 2008-04-15 Therox, Inc. Perfluorocarbon emulsions with non-fluorinated surfactants
US7198179B2 (en) * 2003-02-25 2007-04-03 Therox, Inc. System for storing and dispensing a gas-solubilized product
US6939764B2 (en) * 2003-06-24 2005-09-06 Micron Technology, Inc. Methods of forming memory cells having self-aligned silicide
US20050244354A1 (en) * 2004-04-30 2005-11-03 Sam Speron Oxygenated personal care products
DE102004049574A1 (de) * 2004-10-12 2006-04-20 Doris Dr. Barnikol-Keuten Arzneimittel und System zur perkutanen Arzneistoffverabreichung
US20060147536A1 (en) * 2004-12-30 2006-07-06 Fiore Robert A Method for removing fluids containing dissolved or suspended carbohydrates, lipids, metals, salts, and/or toxins from biological systems
US20060286108A1 (en) * 2005-06-16 2006-12-21 Bell Katherine A Topical compositions for the treatment of chronic wounds
US8445546B2 (en) 2006-10-25 2013-05-21 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
US8784898B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of wound care and treatment
US8597689B2 (en) 2006-10-25 2013-12-03 Revalesio Corporation Methods of wound care and treatment
CA2667614A1 (en) 2006-10-25 2008-09-25 Revalesio Corporation Method of wound care and treatment
WO2008052143A2 (en) 2006-10-25 2008-05-02 Revalesio Corporation Mixing device and output fluids of same
US8784897B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of therapeutic treatment of eyes
US8609148B2 (en) 2006-10-25 2013-12-17 Revalesio Corporation Methods of therapeutic treatment of eyes
US9523090B2 (en) 2007-10-25 2016-12-20 Revalesio Corporation Compositions and methods for treating inflammation
US9745567B2 (en) 2008-04-28 2017-08-29 Revalesio Corporation Compositions and methods for treating multiple sclerosis
US10125359B2 (en) 2007-10-25 2018-11-13 Revalesio Corporation Compositions and methods for treating inflammation
US8618056B2 (en) 2007-12-22 2013-12-31 Cuthbert O. Simpkins Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
US8906855B2 (en) 2007-12-22 2014-12-09 Vivacelle Bio, Inc. Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
US8063020B2 (en) * 2007-12-22 2011-11-22 Simpkins Cuthbert O Resuscitation fluid
US7950370B2 (en) * 2008-03-13 2011-05-31 Cummins Inc. High pressure common rail fuel system with gas injection
CN103919804A (zh) 2008-05-01 2014-07-16 利发利希奥公司 治疗消化功能紊乱的组合物和方法
US8246564B2 (en) 2008-12-04 2012-08-21 Therox, Inc. System for enriching a bodily fluid with a gas having automated priming capabilities
US8192384B2 (en) 2008-12-04 2012-06-05 Therox, Inc. System for enriching a bodily fluid with a gas having a dual-function power switch mechanism
US8636952B2 (en) 2008-12-04 2014-01-28 Therox, Inc. System for enriching a bodily fluid with a gas having a removable gas-enrichment device with an information recording element
EP2391341A4 (de) * 2009-01-30 2012-05-09 Cuthbert O Simpkins Wiederbelebungsflüssigkeit
US8815292B2 (en) 2009-04-27 2014-08-26 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
CA2773181C (en) 2009-09-04 2018-02-27 The University Of North Carolina At Chapel Hill Systems, methods, and computer readable media for high-frequency contrast imaging and image-guided therapeutics
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
EP2498764B1 (de) 2009-11-09 2017-09-06 Spotlight Technology Partners LLC Fragmentierte hydrogele
EP2566460A4 (de) 2010-05-07 2015-12-23 Revalesio Corp Zusammensetzungen und verfahren für verbesserte sportliche leistungen und verkürzte erholungszeiten
MX2013001636A (es) 2010-08-12 2013-05-01 Revalesio Corp Composiciones y metodos para el tratamiento de taupatias
WO2012048335A2 (en) 2010-10-08 2012-04-12 The University Of North Carolina At Chapel Hill Formulation of acoustically activatable particles having low vaporization energy and methods for using same
CA2824056C (en) * 2011-01-14 2019-01-08 Children's Hospital Los Angeles Solution of carbon monoxide for treatment of disease, including sickle cell disease
CN103608065A (zh) * 2011-04-19 2014-02-26 因维希德姆有限责任公司 含过饱和气体物质的生产方法及其透皮给药设备与使用
WO2013086514A1 (en) 2011-12-08 2013-06-13 Pentair Water Pool And Spa, Inc. Aquaculture pump system and method
US10130800B2 (en) 2012-01-27 2018-11-20 Invisiderm, Llc Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof
WO2014055832A1 (en) 2012-10-04 2014-04-10 The University Of North Carolina At Chapel Hill Methods and systems for using encapsulated microbubbles to process biological samples
EP2969158A4 (de) 2013-03-14 2016-12-21 Pentair Water Pool & Spa Inc Kohlendioxidregelungssystem für eine aquakultur
US10219491B2 (en) 2013-03-15 2019-03-05 Pentair Water Pool And Spa, Inc. Dissolved oxygen control system for aquaculture

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3049665T1 (de) * 1979-06-25 1982-03-18 Suntech Use of perfluorocarbon as burn treatment
US5261875A (en) * 1991-02-14 1993-11-16 Wayne State University Method and apparatus for injection of gas hydrates
US5086620A (en) * 1991-02-14 1992-02-11 Wayne State University Method of microencapsulation of hyperbaric gas
US5407426A (en) * 1991-02-14 1995-04-18 Wayne State University Method and apparatus for delivering oxygen into blood
US4761288A (en) * 1984-09-24 1988-08-02 Mezei Associates Limited Multiphase liposomal drug delivery system
EP0186187B1 (de) * 1984-12-27 1992-02-26 Banyu Pharmaceutical Co., Ltd. Cephalosporinverbindungen
DE3501175A1 (de) * 1985-01-16 1986-07-17 Franz-Josef Dipl.-Ing. 4791 Lichtenau Damann Verfahren und vorrichtung zur mischung und loesung von gas in fluessigkeit
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US5847009A (en) * 1986-01-14 1998-12-08 Alliance Pharmaceutical Corp. Prophylaxis in the parenteral administration of particulate dispersions in fluorocarbon emulsions
US5080885A (en) * 1986-01-14 1992-01-14 Alliance Pharmaceutical Corp. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4927623A (en) * 1986-01-14 1990-05-22 Alliance Pharmaceutical Corp. Dissolution of gas in a fluorocarbon liquid
EP0231091B1 (de) * 1986-01-24 1993-03-31 Children's Hospital Medical Center Stabile Emulsionen von stark fluorierten, organischen Verbindungen
US4664680A (en) * 1986-04-07 1987-05-12 Atec Inc. Method and system for enriching oxygen content of water
FR2602774B1 (fr) 1986-07-29 1990-10-19 Atta Nouvelles molecules amphiphiles polyhydroxylees et perfluoroalkylees ayant des proprietes tensioactives
US5243044A (en) * 1986-08-25 1993-09-07 International Therapeutics, Inc. Compounds of perfluoro[3,3,3]propellene and perfluoro hexamethylenetetramine
US4929317A (en) 1986-12-01 1990-05-29 Tokuyama Soda Kabushiki Kaisha Process for preparation of perfluoro organic compounds
US4874509A (en) * 1987-04-24 1989-10-17 Donald Bullock Oxidation saturation device
US4965022A (en) * 1987-07-01 1990-10-23 Union Carbide Industrial Gases Technology Corporation Process for dissolving a gas in a liquid
US5061484A (en) * 1988-03-11 1991-10-29 Alpha Therapeutic Corporation Perfluorochemical emulsion with stabilized vesicles
US4973558A (en) * 1988-04-28 1990-11-27 Endotronics, Inc. Method of culturing cells using highly gas saturated media
US5061688A (en) * 1988-08-19 1991-10-29 Illinois Institute Of Technology Hemoglobin multiple emulsion
GB8909574D0 (en) 1989-04-26 1989-06-14 Ici Plc Chemical process
JP2849471B2 (ja) 1989-06-22 1999-01-20 アライアンス ファーマシューティカル コーポレイション 界面活性剤の性質を有するフッ素およびリン含有両親媒性分子
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
DE3943300A1 (de) * 1989-12-29 1991-07-11 Werner Margrit Dipl Ing Fh System zur sammlung und retransfusion von autologem blut
FR2665705B1 (fr) * 1990-08-09 1993-07-30 Atta Nouveaux derives fluores amphiphiles a structure telomere, leur procede de preparation et leur utilisation dans des preparations a usage biomedical.
US5149321A (en) * 1990-10-10 1992-09-22 Klatz Ronald M Brain resuscitation device and method for performing the same
GB9105167D0 (en) 1991-03-12 1991-04-24 Ici Plc Chemical process
AU2441592A (en) * 1991-08-08 1993-03-02 Leigh D. Segel Fluorocarbon blood substitute
US5304325A (en) * 1991-11-13 1994-04-19 Hemagen/Pfc Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
US5621144A (en) * 1991-11-29 1997-04-15 Isis Innovation Limited Fluorinated compounds as oxygen transport agents
US5344393A (en) * 1992-02-28 1994-09-06 Alliance Pharmaceutical Corp. Use of synthetic oxygen carriers to facilitate oxygen delivery
US5443695A (en) 1993-02-26 1995-08-22 Athens Corporation Distillation apparatus for concentrating less volatile liquids
GB9305349D0 (en) * 1993-03-16 1993-05-05 Nycomed Imaging As Improvements in or relating to contrast agents
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement

Also Published As

Publication number Publication date
US5958377A (en) 1999-09-28
EP0984771A1 (de) 2000-03-15
JP2001502335A (ja) 2001-02-20
US6461590B2 (en) 2002-10-08
JP2009167222A (ja) 2009-07-30
EP0984771B1 (de) 2008-07-30
US5922305A (en) 1999-07-13
CA2268405A1 (en) 1998-04-23
US6197279B1 (en) 2001-03-06
US5834519A (en) 1998-11-10
JP5314489B2 (ja) 2013-10-16
AU4757097A (en) 1998-05-11
EP0984771A4 (de) 2004-09-01
US20010028893A1 (en) 2001-10-11
US6169117B1 (en) 2001-01-02
WO1998016203A1 (en) 1998-04-23
ES2312176T3 (es) 2009-02-16
US6238645B1 (en) 2001-05-29

Similar Documents

Publication Publication Date Title
DE69738874D1 (de) Stabilisierte gasübersättigte emulsionen und suspensionen
DE69739009D1 (de) Gasanalysator
DE69529340D1 (de) Gesteuertes biopsiegerät und analysegerät
ID19316A (id) Pemrosesan gas hidrokarbon
DK0799364T3 (da) Olie- og gasfeltkemikalier
DE69810696T2 (de) Prüfanordnung und Prüfverfahren
ID20234A (id) Pemrosesan gas hidrokarbon
DE59805235D1 (de) Testsystem und testverfahren
DE59509167D1 (de) Gaslaser und Gasnachweis damit
DE959898T1 (de) Laktoferrin varianten und verwendungen davon
DE69724256D1 (de) Gaskompressor
BR9703826A (pt) Dispositivo de excitação de gás
DK0886718T3 (da) Olie- og gasfeltkemikalier
DE69825615D1 (de) Gaseinführung
DE19882580T1 (de) Schneidverfahren und Schneidöl
DE19782033T1 (de) Verbesserte Dichtung für Gasfedern und Dergleichen
NO995420L (no) Gass- og faststoffreduserende slurry-fallroer
EE04509B1 (et) Kokkupandav klaviatuur ja meetod klaviatuuri valmistamiseks
DE59914173D1 (de) Zündanlage und zündsteuerverfahren
DE69842206D1 (de) Echounterdrücker und echounterdrückungsverfahren
DE69826826D1 (de) Gasanalysegerät
DE59702772D1 (de) Gaslaseranordnung
DE59805607D1 (de) Ventilanordnung und dafür vorgesehenes ventil
DE59708683D1 (de) Kupfer-Chrom-Titan-Silizium-Legierung und ihre Verwendung
NO992508D0 (no) Gasskompressor

Legal Events

Date Code Title Description
8364 No opposition during term of opposition