DE69830598D1 - Optische vorrichtung und methode - Google Patents

Optische vorrichtung und methode

Info

Publication number
DE69830598D1
DE69830598D1 DE69830598T DE69830598T DE69830598D1 DE 69830598 D1 DE69830598 D1 DE 69830598D1 DE 69830598 T DE69830598 T DE 69830598T DE 69830598 T DE69830598 T DE 69830598T DE 69830598 D1 DE69830598 D1 DE 69830598D1
Authority
DE
Germany
Prior art keywords
reflectors
light
ellipsoid
revolution
prism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69830598T
Other languages
English (en)
Other versions
DE69830598T2 (de
Inventor
Johnathan Sharpe
Niven Schaare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
XY LLC
Original Assignee
Horticulture & Food Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horticulture & Food Res Inst filed Critical Horticulture & Food Res Inst
Publication of DE69830598D1 publication Critical patent/DE69830598D1/de
Application granted granted Critical
Publication of DE69830598T2 publication Critical patent/DE69830598T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N15/1436—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/04—Prisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G01N15/149—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N2015/1452—Adjustment of focus; Alignment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6469—Cavity, e.g. ellipsoid
DE69830598T 1997-01-31 1998-02-02 Optische vorrichtung und methode Expired - Lifetime DE69830598T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ31416997 1997-01-31
NZ31416997 1997-01-31
PCT/NZ1998/000009 WO1998034094A1 (en) 1997-01-31 1998-02-02 Optical apparatus

Publications (2)

Publication Number Publication Date
DE69830598D1 true DE69830598D1 (de) 2005-07-21
DE69830598T2 DE69830598T2 (de) 2006-05-18

Family

ID=19926129

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69830598T Expired - Lifetime DE69830598T2 (de) 1997-01-31 1998-02-02 Optische vorrichtung und methode

Country Status (8)

Country Link
US (8) US6819411B1 (de)
EP (4) EP1017987B1 (de)
JP (4) JP4323571B2 (de)
AT (1) ATE298084T1 (de)
AU (1) AU752985B2 (de)
CA (1) CA2279574C (de)
DE (1) DE69830598T2 (de)
WO (1) WO1998034094A1 (de)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1017987B1 (de) * 1997-01-31 2005-06-15 The Horticulture And Food Research Institute Of New Zealand Limited Optische vorrichtung und methode
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
DE69942959D1 (de) 1998-07-30 2010-12-30 Xy Llc Pferdesystem für die künstliche Befruchtung ohne chirurgischen Eingriff
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
PL359598A1 (en) * 2000-05-09 2004-08-23 Xy, Inc. High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
AU3651701A (en) 2000-10-05 2002-04-15 Xy Inc System of hysteroscopic insemination of mares
CA2468774C (en) 2000-11-29 2015-06-30 George E. Seidel System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002092247A1 (en) * 2001-05-17 2002-11-21 Cytomation, Inc. Flow cytometer with active automated optical alignment system
DE10202999B4 (de) * 2002-01-26 2004-04-15 Palas Gmbh Partikel- Und Lasermesstechnik Verfahren und Vorrichtung zum Messen der Größenverteilung und Konzentration von Partikeln in einem Fluid
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
MXPA05001100A (es) 2002-08-01 2005-04-28 Xy Inc Sistema de separacion de baja presion para celulas de esperma.
AU2003250800A1 (en) * 2002-08-02 2004-03-03 Siemens Aktiengesellschaft Evaluation of received useful information by the detection of error concealment
AU2003265471B2 (en) 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US6936828B2 (en) 2003-02-14 2005-08-30 Honeywell International Inc. Particle detection system and method
JP4614947B2 (ja) * 2003-03-28 2011-01-19 イングラン・リミテッド・ライアビリティ・カンパニー 粒子を仕分けるためおよび性別で仕分けられた動物の精子を提供するための装置、および方法
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
FR2860869B1 (fr) * 2003-10-10 2007-04-20 Optis Dispositif portable de mesure de l'intensite lumineuse d'un objet et utilisation d'un tel dispositif
PL2151243T3 (pl) 2004-03-29 2013-03-29 Inguran Llc Zawiesiny plemników do sortowania na populacje wzbogacone w niosące chromosom X lub Y
AU2005266930B2 (en) 2004-07-22 2010-09-16 Inguran, Llc Process for enriching a population of sperm cells
US7430046B2 (en) * 2004-07-30 2008-09-30 Biovigilant Systems, Inc. Pathogen and particle detector system and method
US7110192B2 (en) * 2005-01-12 2006-09-19 Dako Denmark A/S System and method for a composite lens for a flow cytometer
DE102005031647A1 (de) * 2005-07-06 2007-01-11 Chromasens Gmbh Beleuchtungsvorrichtung zur Dunkelfeldbeleuchtung für eine optische Testvorrichtung und Verfahren zum optischen Abtasten eines Objektes
KR101283071B1 (ko) 2005-07-15 2013-07-05 바이오비질런트 시스템즈 인코포레이티드 병원체 및 입자 검출기 시스템 및 방법
WO2007041458A2 (en) * 2005-10-03 2007-04-12 The Salk Institute For Biological Studies Maximal-aperture reflecting objective
DE102005054184B4 (de) 2005-11-14 2020-10-29 Carl Zeiss Microscopy Gmbh Multispektrale Beleuchtungsvorrichtung und Messverfahren
US7671985B1 (en) * 2006-03-13 2010-03-02 Milan Milosevic Device for small spot analysis using fiber optic interfaced spectrometers
CN101467306B (zh) * 2006-04-24 2012-12-26 睿励科学仪器（上海）有限公司 光谱椭偏仪
AU2007281902A1 (en) * 2006-08-04 2008-02-14 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health Wide-area fluorescence detection system for multi-photon microscopy
US20080055755A1 (en) * 2006-08-31 2008-03-06 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Electromagnetic device and method
CN101236150B (zh) * 2007-02-02 2012-09-05 深圳迈瑞生物医疗电子股份有限公司 用于基于流式细胞术的仪器的光电传感器及其照射单元
US7796253B2 (en) * 2007-04-16 2010-09-14 Kabushiki Kaisha Toshiba Image forming apparatus for forming image on record medium
WO2009063322A2 (en) * 2007-08-15 2009-05-22 Malvern Instruments Ltd Broad-range spectrometer
JP5252892B2 (ja) * 2007-11-20 2013-07-31 オリンパス株式会社 光学ユニット
US8628976B2 (en) 2007-12-03 2014-01-14 Azbil BioVigilant, Inc. Method for the detection of biologic particle contamination
WO2009073649A1 (en) * 2007-12-04 2009-06-11 Particle Measuring Systems, Inc. Non-orthogonal particle detection systems and methods
DE202008009859U1 (de) * 2007-12-21 2009-03-05 Berthold Technologies Gmbh & Co. Kg Vorrichtung zur wahlweisen Messung von insbesondere Lumineszenz- und/oder Fluoreszenzstrahlung
JP2009156659A (ja) * 2007-12-26 2009-07-16 Olympus Corp 測定装置及び測定方法
CN102087197B (zh) * 2009-12-08 2014-06-18 龚维燕 全功能血液分析仪器中库尔特微孔的共轴照明方法及其分析仪器
CN101965579B (zh) * 2008-02-05 2013-04-24 雷利恩特技术有限责任公司 使用展像段的光学图案生成器
JP4998618B2 (ja) * 2008-05-15 2012-08-15 株式会社島津製作所 生体画像撮影装置
US9013692B2 (en) 2008-06-12 2015-04-21 East Carolina University Flow cytometer apparatus for three dimensional difraction imaging and related methods
NZ590166A (en) 2008-06-30 2013-09-27 Microbix Biosystems Inc Method and apparatus for sorting cells
CN102144154B (zh) 2008-10-01 2015-04-22 东卡莱罗纳大学 用结构入射光测定混浊介质光学特征的方法与系统
WO2010080642A1 (en) * 2008-12-18 2010-07-15 Biovigilant Systems, Inc. Compact detector for simultaneous particle size and fluorescence detection
US8512224B2 (en) * 2009-01-24 2013-08-20 Xy, Llc Method of producing an inseminate
US8251887B2 (en) * 2009-01-24 2012-08-28 Xihe Li Reproductive technology of low dose semen production and in vitro/in vitro fertilization in domestic animals
US8665439B2 (en) 2009-06-30 2014-03-04 Microbix Biosystems, Inc. Method and apparatus for limiting effects of refraction in cytometry
JP5394504B2 (ja) * 2009-10-30 2014-01-22 富士通フロンテック株式会社 撮像装置の照明光学系
EP2545356B1 (de) * 2010-03-09 2015-12-02 Beckman Coulter, Inc. Berechnete tropfverzögerung für flusszytometriesysteme und verfahren dafür
US20110223586A1 (en) * 2010-03-11 2011-09-15 David Karabinus Optical particle characterization system
US20110223587A1 (en) * 2010-03-11 2011-09-15 Schulman Joseph D Optical particle characterization system
JP2012026837A (ja) * 2010-07-22 2012-02-09 Sony Corp 微小粒子測定装置
US8729502B1 (en) 2010-10-28 2014-05-20 The Research Foundation For The State University Of New York Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection
CA2826544C (en) * 2011-02-04 2020-06-30 Cytonome/St, Llc Particle sorting apparatus and method
CA2826914C (en) * 2011-02-15 2020-12-01 Microbix Biosystems Inc. Methods, systems, and apparatus for performing flow cytometry
US9625810B2 (en) * 2011-03-16 2017-04-18 Kla-Tencor Corporation Source multiplexing illumination for mask inspection
KR20140016923A (ko) * 2011-04-06 2014-02-10 인스턴트 바이오스캔, 엘엘씨 미생물 검출 장치 및 방법
CN102553830B (zh) * 2011-12-16 2014-12-03 东南大学 一种激光扫描分拣机
JP2013160672A (ja) 2012-02-07 2013-08-19 Sony Corp 蛍光検出用光学系及び微小粒子分析装置
US8879797B2 (en) * 2012-05-25 2014-11-04 Fluid Imaging Technologies, Inc. System and method for total internal reflection enhanced imaging flow cytometry
US9888990B2 (en) 2012-06-06 2018-02-13 Inguran, Llc Methods for use of sex sorted semen to improve genetic management in swine
US9433195B2 (en) 2012-06-06 2016-09-06 Inguran, Llc Methods for increasing genetic progress in a line or breed of swine using sex-selected sperm cells
JP5841498B2 (ja) * 2012-06-18 2016-01-13 国立大学法人東京工業大学 対象物検出装置
CN103575632B (zh) * 2012-08-09 2015-09-23 深圳开立生物医疗科技股份有限公司 一种鞘流装置及血液分析仪
US8919194B2 (en) 2012-09-05 2014-12-30 Simmonds Precision Products, Inc. Liquid level gauging system with bubble shedding reflectors
DE102012108347A1 (de) * 2012-09-07 2014-03-13 Limo Patentverwaltung Gmbh & Co. Kg Verfahren und Vorrichtung zur Fokussierung von Laserlicht
WO2014087380A1 (en) * 2012-12-05 2014-06-12 Genepoc Inc. Optical interrogation device
EP2984468B1 (de) 2013-04-12 2021-11-17 Becton, Dickinson and Company Automatisiertes setup für eine zellsortierung
WO2015056628A1 (ja) * 2013-10-15 2015-04-23 独立行政法人産業技術総合研究所 光学測定装置及び光学系を備える装置
CN103676436B (zh) * 2013-12-20 2016-04-06 海信集团有限公司 一种用于投影的光源整形方法及结构
US9551645B2 (en) 2014-07-10 2017-01-24 Kinetic River Corp. Flow cytometry apparatus and methods
KR102241978B1 (ko) * 2014-09-11 2021-04-19 삼성전자주식회사 피검체의 표면 검사 방법 및 이를 수행하기 위한 광학 시스템
DE102015114756B4 (de) * 2014-09-25 2021-07-22 Leica Microsystems Cms Gmbh Spiegelvorrichtung
WO2016094065A1 (en) 2014-12-12 2016-06-16 Becton, Dickinson And Company Methods for aligning a light source with a flow stream and systems thereof
FR3034578B1 (fr) * 2015-03-30 2018-04-27 Horiba Abx Sas Procede et dispositif de declenchement de sources lumineuses impulsionnelles
AU2016304897A1 (en) 2015-08-11 2018-01-25 Paul Anthony Iorio Stormwater biofiltration system and method
JP5943366B1 (ja) * 2015-08-28 2016-07-05 株式会社サタケ 光学ユニットを備えた装置
KR102114628B1 (ko) 2015-08-31 2020-05-25 휴렛-팩커드 디벨롭먼트 컴퍼니, 엘.피. 스펙트럼 현미경
US9983115B2 (en) 2015-09-21 2018-05-29 Fluid Imaging Technologies, Inc. System and method for monitoring particles in a fluid using ratiometric cytometry
RU2018110083A (ru) 2015-09-30 2019-09-24 Сони Корпорейшн Разъем для оптической связи, кабель для оптической связи и электронное устройство
US10302545B2 (en) 2015-10-05 2019-05-28 Becton, Dickinson And Company Automated drop delay calculation
CN113702269B (zh) * 2016-01-21 2024-04-09 东京毅力科创株式会社 药液供给装置和涂敷显影系统
US10365198B2 (en) * 2016-04-21 2019-07-30 Malvern Panalytical Limited Particle characterization
DE102016113042A1 (de) * 2016-07-15 2018-01-18 B. Braun Melsungen Ag Durchflussmesszellenvorrichtung zur Messung von Fluidparametern
USD869676S1 (en) 2017-03-28 2019-12-10 Becton, Dickinson And Company Particle sorting module
USD868991S1 (en) 2017-03-28 2019-12-03 Becton, Dickinson And Company Register block
DE102017115661A1 (de) * 2017-07-12 2019-01-17 Endress+Hauser Conducta Gmbh+Co. Kg Optischer Sensor
US11696747B2 (en) 2017-09-29 2023-07-11 Nanovare Sas Devices and methods for semen analysis
US11422094B2 (en) * 2018-01-11 2022-08-23 Universiteit Hasselt Analysis of data obtained by fluorescence fluctuation microscopy from a plurality of dyes
USD872296S1 (en) 2018-01-30 2020-01-07 Becton, Dickinson And Company Particle sorting module
USD876668S1 (en) 2018-01-30 2020-02-25 Becton, Dickinson And Company Particle sorting module mount
USD882817S1 (en) 2018-01-30 2020-04-28 Becton, Dickinson And Company Sample container
USD864415S1 (en) 2018-01-30 2019-10-22 Becton, Dickinson And Company Particle sorting system
US11314074B2 (en) 2018-03-12 2022-04-26 The University Of North Carolina At Chapel Hill Light disc microscopy for fluorescence microscopes
WO2019178093A1 (en) * 2018-03-12 2019-09-19 The University Of North Carolina At Chapel Hill Mirror image microscopy for increased collection
CN108801883B (zh) * 2018-04-19 2021-01-05 深圳市趣方科技有限公司 一种微小悬浮颗粒流动光学检测机构以及检测方法
CA3106121A1 (en) * 2018-07-10 2020-01-16 Gerrit Jan Van Den Engh System, apparatus and method for off-axis illumination in flow cytometry
US11858008B2 (en) 2021-03-26 2024-01-02 Cytonome/St, Llc Systems and methods for particle sorting with automated adjustment of operational parameters
RU2763682C1 (ru) * 2021-06-09 2021-12-30 Геннадий Евгеньевич Котковский Оптическая система для определения составов аэрозолей на основе люминесцентного анализа аэрозольных частиц
WO2023053438A1 (ja) 2021-10-01 2023-04-06 株式会社テックジェーピー 細径ビーム生成装置

Family Cites Families (671)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US32350A (en) * 1861-05-21 Improvement in machines for turning and spreading hay
US2149735A (en) * 1935-07-08 1939-03-07 Alan W Ross Photosensitive measuring instrument
US3005756A (en) 1958-11-14 1961-10-24 Noland L Van Demark Diluter containing carbon dioxide for preserving semen
US3299354A (en) 1962-07-05 1967-01-17 Coulter Electronics Aperture tube structure for particle study apparatus
US3499435A (en) * 1967-06-02 1970-03-10 Paul E Rockwell Esophageal probe for use in monitoring
US3547526A (en) 1967-10-26 1970-12-15 Kollsman Instr Corp Optical beam cross-section converter
US3810010A (en) 1968-11-02 1974-05-07 Telefunken Patent Particle analysis method and apparatus wherein liquid containing particles is sucked into a constricted flow path
US3829216A (en) 1968-11-26 1974-08-13 M Persidsky Optical system and method for counting sperm cells
DE1815352C3 (de) 1968-12-18 1975-03-20 Wolfgang Prof. Dr. Dittrich Automatisches MeB- und Zählgerät für die Teilchen einer Dispersion
US4327177A (en) * 1969-04-10 1982-04-27 Wallace Shrimpton Method and means for controlling the sex of mammalian offspring and product therefor
US3894529A (en) 1969-04-10 1975-07-15 Bio Controls Inc Method and means for controlling the sex of mammalian offspring and product therefor
US4474875A (en) 1969-04-10 1984-10-02 Wallace Shrimpton Method and means for controlling the sex of mammalian offspring and product therefor
DE1919628C3 (de) 1969-04-18 1975-04-10 Wolfgang Prof. Dr. Dittrich Anordnung zum automatischen Zählen und/oder Klassifizieren von in einem strömungsfähigen Medium dispergierten Teilchen
US3687806A (en) 1969-11-04 1972-08-29 Bio Controls Inc Method for controlling sex of mammalian offspring
US3788744A (en) 1970-01-14 1974-01-29 Bio Physics Systems Inc Method and apparatus for photoanalysis
US3661460A (en) 1970-08-28 1972-05-09 Technicon Instr Method and apparatus for optical analysis of the contents of a sheathed stream
US3816249A (en) 1970-11-23 1974-06-11 B Bhattacharya Universal medium and method for extending the useful life of semen in vitro
US3644128A (en) * 1970-12-28 1972-02-22 Stuart Lipner Method of preparing comminuted meat products
US3756459A (en) 1971-01-12 1973-09-04 Damon Corp Method and apparatus for metering fluid utilizing pressure differentials
US3916143A (en) 1971-04-22 1975-10-28 Research Corp Branding living animals
US3791384A (en) 1971-07-15 1974-02-12 Schaumann H Artificial insemination of sows
US3833796A (en) 1971-10-13 1974-09-03 Georgia Tech Res Inst Method and apparatus for chromosome digitizing
BE793185A (fr) 1971-12-23 1973-04-16 Atomic Energy Commission Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques
US3826364A (en) 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3761941A (en) 1972-10-13 1973-09-25 Mead Corp Phase control for a drop generating and charging system
CA1029833A (en) 1973-02-23 1978-04-18 Hildegarde Goehde Apparatus for the automatic counting and measuring of suspended particles
US3791517A (en) 1973-03-05 1974-02-12 Bio Physics Systems Inc Digital fluidic amplifier particle sorter
US4009260A (en) * 1973-04-19 1977-02-22 Schering Aktiengesellschaft Fractionation of sperm
US3893766A (en) 1973-06-14 1975-07-08 Coulter Electronics Apparatus for orienting generally flat particles for slit-scan photometry
USRE29141E (en) 1973-06-14 1977-02-22 Coulter Electronics, Inc. Apparatus for orienting generally flat particles for sensing
JPS5613928B2 (de) * 1973-07-13 1981-04-01
US3947093A (en) 1973-06-28 1976-03-30 Canon Kabushiki Kaisha Optical device for producing a minute light beam
JPS5023242A (de) * 1973-06-28 1975-03-12
US3944917A (en) 1973-08-13 1976-03-16 Coulter Electronics, Inc. Electrical sensing circuitry for particle analyzing device
US3909744A (en) * 1973-09-24 1975-09-30 United Technologies Corp Unstable resonator system producing a high irradiance beam in the far field
US3906929A (en) 1973-11-23 1975-09-23 Lynn Lawrence Augspurger Processes for reproduction of cellular bodies
FR2254639B1 (de) 1973-12-18 1978-06-02 Agronomique Inst Nat Rech
US4070617A (en) 1974-05-08 1978-01-24 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Device for controlling the particle flow in an apparatus for measuring the properties of particles suspended in liquid
US3973196A (en) 1974-05-24 1976-08-03 Coulter Electronics, Inc. Method and apparatus for ejecting a metered amount of particulate sample
US3963606A (en) 1974-06-03 1976-06-15 Coulter Electronics, Inc. Semi-automatic adjusting delay for an electronic particle separator
US3877430A (en) * 1974-07-17 1975-04-15 Horst K Wieder Artificial insemination apparatus
US4083957A (en) * 1974-07-26 1978-04-11 Lang John L Process for the alteration of the sex-ratio of mammals
US4006360A (en) 1974-08-21 1977-02-01 Block Engineering, Inc. Method of discriminating between dyed particles and background fluorescence of the dye
US3920993A (en) * 1974-09-18 1975-11-18 Beckman Instruments Inc Piggyback optical bench
US3999855A (en) 1974-10-24 1976-12-28 Block Engineering, Inc. Illumination system
US4092229A (en) * 1975-12-17 1978-05-30 Bhattacharya Bhairab C Thermal convection counter streaming sedimentation and forced convection galvanization method for controlling the sex of mammalian offspring
USRE32350E (en) 1974-11-22 1987-02-10 Bhairab C. Bhattacharya Thermal convection counter streaming sedimentation and forced convection galvanization method for controlling the sex of mammalian offspring
US3976197A (en) * 1974-11-22 1976-08-24 Bhattacharya Bhairab C Thermal convection counter streaming sedimentation method and apparatus for controlling the sex of mammalian offspring
US4014611A (en) 1975-04-30 1977-03-29 Coulter Electronics, Inc. Aperture module for use in particle testing apparatus
US3989381A (en) * 1975-05-05 1976-11-02 Coulter Electronics, Inc. Optical chamber with spherical reflective portion and apparatus employing same
DE2521236C3 (de) 1975-05-10 1978-12-14 Hildegard Dr. 4400 Muenster Goehde Geb. Kuhl Einrichtung zum Zählen und Messen von in einer Flüssigkeit suspendierten Teilchen
US3960449A (en) 1975-06-05 1976-06-01 The Board Of Trustees Of Leland Stanford Junior University Measurement of angular dependence of scattered light in a flowing stream
US4058732A (en) 1975-06-30 1977-11-15 Analytical Radiation Corporation Method and apparatus for improved analytical fluorescent spectroscopy
US4021117A (en) 1975-08-07 1977-05-03 Hildegard Gohde Process for automatic counting and measurement of particles
US4007087A (en) * 1975-10-17 1977-02-08 Gametrics Limited Sperm fractionation and storage
AU2154077A (en) * 1976-01-27 1978-07-27 Univ Edinburgh Control of sex ratio in mammalian offspring
DE2710030C3 (de) * 1976-03-11 1981-06-19 Novosibirskij Inst Org Chimii Vorrichtung zur Photometrierung eines in einer zylindrischen Küvette befindlichen Stoffes
US4162282A (en) 1976-04-22 1979-07-24 Coulter Electronics, Inc. Method for producing uniform particles
US4302166A (en) 1976-04-22 1981-11-24 Coulter Electronics, Inc. Droplet forming apparatus for use in producing uniform particles
JPS5319891A (en) 1976-06-10 1978-02-23 Coulter Electronics Method and apparatus for folling drop formation and separation
GB1583150A (en) 1976-08-02 1981-01-21 Milk Marketing Board Apparatus for collecting eggs
US4110604A (en) 1976-11-04 1978-08-29 Becton, Dickinson And Company Particle density measuring system
DE2709399C3 (de) 1977-03-04 1980-07-24 Goehde, Wolfgang, Dr., 4400 Muenster Einrichtung zum Messen von Zelleigenschaften
DE2716095A1 (de) 1977-04-12 1978-10-19 Zoeld Tibor Dr Phys Gasgesteuertes verfahren zum sortieren von in einem elektrolyten suspendierten teilchen und vorrichtung zur durchfuehrung des verfahrens
US4448767A (en) * 1977-10-11 1984-05-15 Sumar Corporation Preparation of monospecific male-specific antibody and the use thereof for increasing the percentage of mammalian offspring of either sex
US4191749A (en) * 1977-10-11 1980-03-04 Bryant Bernard J Method and material for increasing the percentage of mammalian offspring of either sex
US4188543A (en) * 1978-03-20 1980-02-12 Coulter Electronics, Inc. Ellipsoid radiation collector apparatus and method
US4189236A (en) 1978-03-20 1980-02-19 Coulter Electronics, Inc. Ellipsoid-conic radiation collector and method
US4179218A (en) * 1978-05-15 1979-12-18 The Boeing Company Particle size analyzer
US4251733A (en) * 1978-06-29 1981-02-17 Hirleman Jr Edwin D Technique for simultaneous particle size and velocity measurement
DE2832091A1 (de) 1978-07-21 1980-01-31 Eidenschink Henning Optisches verfahren zur bestimmung der teilchengroesse kolloidaler loesungen und messgeraet zur durchfuehrung des verfahrens
US4199686A (en) * 1978-07-31 1980-04-22 Coulter Electronics, Inc. Dark field illuminator and collector apparatus and method
US4276139A (en) 1978-08-16 1981-06-30 Lawson Rommon L Process for magnetic separation and collection of viable female and male spermatozoa
US4225405A (en) 1978-08-16 1980-09-30 Lawson Rommom L Process for separation and collection of viable female and male spermatozoa
US4230558A (en) 1978-10-02 1980-10-28 Coulter Electronics, Inc. Single drop separator
DE3000034A1 (de) * 1979-01-02 1980-07-31 Coulter Electronics Verfahren und vorrichtung zum messen der richtungsverteilungseigenschaften der von einem teilchen zurueckgestrahlten strahlungsenergie
US4341471A (en) 1979-01-02 1982-07-27 Coulter Electronics, Inc. Apparatus and method for measuring the distribution of radiant energy produced in particle investigating systems
SE428972B (sv) * 1979-03-07 1983-08-01 Svenska Utvecklings Ab Anordning for detektering av forekommande av svevande, fasta eller vetskeformade partiklar i en gas
US4267268A (en) * 1979-03-12 1981-05-12 Nelson Jr Robert A Spermatozoa extenders
US4274408A (en) 1979-03-26 1981-06-23 Beatrice Nimrod Method for guide-wire placement and novel syringe therefor
US4200802A (en) * 1979-03-28 1980-04-29 The United States Of America As Represented By The United States Department Of Energy Parabolic cell analyzer
US4408877A (en) 1979-04-10 1983-10-11 Ernst Leitz Wetzlar Gmbh Device for hydrodynamic focussing of a particle-suspension in a liquid flow cytophotometer
NO144002C (no) 1979-04-10 1981-05-27 Norsk Hydro S Inst For Kreftfo Anordning for anvendelse ved vaeskestroemsfotometri
US4255021A (en) * 1979-04-20 1981-03-10 The United States Of America As Represented By The United States Department Of Energy Optical device with conical input and output prism faces
US4263508A (en) 1979-04-20 1981-04-21 Research Corporation Pulse edge measurement for determining particle dimensional characteristics
JPS5613928A (en) 1979-07-17 1981-02-10 Duskin Franchise Co Method of deodorizing in case of cleaning
US4318480A (en) 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device
US4318481A (en) 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method for automatically setting the correct phase of the charge pulses in an electrostatic flow sorter
US4318482A (en) 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method for measuring the velocity of a perturbed jetting fluid in an electrostatic particle sorting system
US4325483A (en) 1979-08-20 1982-04-20 Ortho Diagnostics, Inc. Method for detecting and controlling flow rates of the droplet forming stream of an electrostatic particle sorting apparatus
US4317520A (en) 1979-08-20 1982-03-02 Ortho Diagnostics, Inc. Servo system to control the spatial position of droplet formation of a fluid jet in a cell sorting apparatus
US4318483A (en) 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Automatic relative droplet charging time delay system for an electrostatic particle sorting system using a relatively moveable stream surface sensing system
DE2943116C2 (de) 1979-10-25 1986-06-19 Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München Einrichtung zur durchflußcytometrischen Reaktions- und/oder Diffusionsmessung
US4284355A (en) 1979-10-29 1981-08-18 Ortho Diagnostics, Inc. Automated method for cell volume determination
US4400764A (en) 1980-02-05 1983-08-23 The Boeing Company Low backscatter illumination system
US4367043A (en) 1980-05-05 1983-01-04 Leland Stanford Junior University Method and means for delivering liquid samples to a sample scanning device
US4362246A (en) 1980-07-14 1982-12-07 Adair Edwin Lloyd Method of treating collected mammal semen and separating sperm into X Y components
US4348107A (en) * 1980-07-18 1982-09-07 Coulter Electronics, Inc. Orifice inside optical element
EP0046345A3 (de) 1980-08-15 1982-03-03 Ortho Diagnostic Systems Inc. Kontrollierte hydrodynamische Durchflusseinrichtung in einem Durchflusszytometerapparat
US4350410A (en) 1980-10-08 1982-09-21 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Multiprism collimator
US4691829A (en) 1980-11-03 1987-09-08 Coulter Corporation Method of and apparatus for detecting change in the breakoff point in a droplet generation system
US4487320A (en) 1980-11-03 1984-12-11 Coulter Corporation Method of and apparatus for detecting change in the breakoff point in a droplet generation system
US4395676A (en) 1980-11-24 1983-07-26 Coulter Electronics, Inc. Focused aperture module
US4361400A (en) 1980-11-26 1982-11-30 The United States Of America As Represented By The United States Department Of Energy Fluidic assembly for an ultra-high-speed chromosome flow sorter
US4680258A (en) 1981-03-24 1987-07-14 Sloan-Kettering Institute For Cancer Research Process for sex determination in man by use of monoclonal antibodies to the H-Y antigen
US4673288A (en) 1981-05-15 1987-06-16 Ratcom, Inc. Flow cytometry
US4818103A (en) 1981-05-15 1989-04-04 Ratcom Flow cytometry
EP0068404B1 (de) 1981-06-24 1985-10-02 Becton Dickinson and Company Analysator zur gleichzeitigen Bestimmung des Volumens und der Lichtemissionseigenschaften von Partikeln
FR2510393A1 (fr) 1981-07-31 1983-02-04 Bertrand Cassou Appareil de transfert d'elements de reproduction animale, tels que des embryons
US4339434A (en) 1981-08-17 1982-07-13 Gametrics Limited Method of increasing the incidence of female offspring
US4395397A (en) 1981-09-17 1983-07-26 Sidney Farber Cancer Institute, Inc. Apparatus and method for killing unwanted cells
US4422761A (en) * 1981-09-28 1983-12-27 Frommer Joseph C Photo-electric particle sensing system
US4515274A (en) 1981-12-02 1985-05-07 Coulter Corporation Particle analyzing and sorting apparatus
SU1056008A1 (ru) 1982-01-25 1983-11-23 Предприятие П/Я Р-6681 Проточный цитофлуориметр
JPS59500340A (ja) 1982-03-08 1984-03-01 モトロ−ラ・インコ−ポレ−テツド 集積回路のリ−ドフレ−ム
US4511661A (en) 1982-03-19 1985-04-16 University Patents, Inc. ATCC HB8116 And its monoclonal anti-H-Y antibody, Hyclonalan
US4498766A (en) 1982-03-25 1985-02-12 Becton, Dickinson And Company Light beam focal spot elongation in flow cytometry devices
DE3315195A1 (de) 1982-04-29 1983-11-03 International Remote Imaging Systems Inc., 91311 Chatsworth, Calif. Verfahren zum ausrichten von teilchen in einer fluidprobe
DE3315194A1 (de) 1982-04-29 1983-11-03 International Remote Imaging Systems Inc., 91311 Chatsworth, Calif. Verfahren zum trennen von in einer fluidprobe stroemenden teilchen
US4629687A (en) 1982-07-29 1986-12-16 Board Of Trustees Of Michigan State University Positive selection sorting of cells
GB2125181B (en) 1982-08-11 1986-01-29 Coulter Electronics Flow cells for particle study
US4559309A (en) 1982-09-01 1985-12-17 Memorial Sloan Kettering Cancer Center Flow cytometry-fluorescence measurements for characterizing sperm
WO1984001265A1 (en) 1982-10-05 1984-04-12 Genetic Engineering Inc Method of treating collected mammal semen and separating sperm into x and y components
FR2535053B1 (fr) * 1982-10-22 1985-06-21 Saint Etienne Universite Appareil d'identification optique des proprietes multiparametriques individuelles de particules ou objets en flux continu
US4501366A (en) * 1982-12-14 1985-02-26 Adolph Coors Company Photomultiplier tube assembly
DE3372137D1 (en) 1982-12-21 1987-07-23 Crosfield Electronics Ltd Light beam-splitter
US4492436A (en) 1983-01-03 1985-01-08 At&T Bell Laboratories Polarization independent beam splitter
JPS59143146A (ja) 1983-02-07 1984-08-16 Nippon Kogaku Kk <Nikon> ミラ−集光型照明光学系
CA1206559A (en) 1983-03-04 1986-06-24 Robert E. Auer Method of and apparatus for detecting change in the breakoff point of a droplet generation system
IT1197570B (it) 1983-02-11 1988-12-06 Serono Ist Farm Miscele di fsh e lh da ipofisi porcine in rapporto definito
CH651930A5 (en) 1983-03-24 1985-10-15 Coulter Corp Apparatus for analysis and sorting of particles
JPS59174742A (ja) 1983-03-25 1984-10-03 Agency Of Ind Science & Technol 微小粒子を区分又は選別する方法及びその装置
GB2145112B (en) 1983-04-27 1987-02-18 Milk Marketing Board Sorting living spermatozoa
US4523809A (en) 1983-08-04 1985-06-18 The United States Of America As Represented By The Secretary Of The Air Force Method and apparatus for generating a structured light beam array
NZ207393A (en) 1983-08-05 1987-03-31 Neal Lloyd First Staining dna in living cells
US4538733A (en) 1983-10-14 1985-09-03 Becton, Dickinson And Company Particle sorter with neutralized collection wells and method of using same
US4585736A (en) 1983-10-18 1986-04-29 The United States Of America As Represented By The United States Department Of Energy Flow cytometric measurement of total DNA and incorporated halodeoxyuridine
US4780406A (en) 1983-10-18 1988-10-25 The Regents Of The University Of California Flow cytometric measurement of total DNA and incorporated halodeoxyuridine
US4606636A (en) * 1983-10-25 1986-08-19 Universite De Saint-Etienne Optical apparatus for identifying the individual multiparametric properties of particles or bodies in a continuous flow
JPS6093944A (ja) * 1983-10-28 1985-05-25 Satoshi Okuda 光散乱粒子測定装置
US4735504A (en) 1983-10-31 1988-04-05 Technicon Instruments Corporation Method and apparatus for determining the volume & index of refraction of particles
EP0148497B1 (de) 1983-12-24 1990-10-31 Inotech Ag Vorrichtung zum Führen und Sammeln von Licht in der Fotometrie od. dgl.
US4573796A (en) 1984-01-06 1986-03-04 The United States Of America As Represented By The United States Department Of Energy Apparatus for eliminating background interference in fluorescence measurements
US4631483A (en) 1984-02-01 1986-12-23 Coulter Electronics, Inc. Particle analyzing apparatus and method of moving particles in suspension through such apparatus
US4714680B1 (en) 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
US4965204A (en) 1984-02-06 1990-10-23 The Johns Hopkins University Human stem cells and monoclonal antibodies
EP0172242A1 (de) * 1984-02-29 1986-02-26 Research Corporation Durchflusszellanalysegerät
US4545677A (en) 1984-03-05 1985-10-08 Becton, Dickinson And Company Prismatic beam expander for light beam shaping in a flow cytometry apparatus
US4600302A (en) 1984-03-26 1986-07-15 Becton, Dickinson And Company Flow cytometry apparatus with uniform incoherent light excitation
JPS60205335A (ja) * 1984-03-30 1985-10-16 Shimadzu Corp シ−スフロ−セル装置
DE3412620A1 (de) 1984-04-04 1985-10-17 Basf Ag, 6700 Ludwigshafen Laseroptische anordnung zur messung des dispergiergrades in stroemenden systemen
US4609286A (en) 1984-04-16 1986-09-02 Becton, Dickinson And Company Dispersion prism for separation of wavelengths of spectrally rich light in a flow cytometry apparatus
US4605558A (en) 1984-04-20 1986-08-12 Wallace Shrimpton Process for cell separation
US4660971A (en) 1984-05-03 1987-04-28 Becton, Dickinson And Company Optical features of flow cytometry apparatus
FR2563726B1 (fr) * 1984-05-04 1986-10-10 Robert Cassou Appareil d'insemination artificielle, notamment des carnivores
FR2566543B1 (fr) 1984-06-20 1988-02-26 Commissariat Energie Atomique Dispositif optique a rendement de collection eleve et cytofluorimetre en faisant application
DE3580418D1 (de) 1984-07-31 1990-12-13 Hitachi Ltd Elektrophoretisches trennverfahren mit freier stroemung und apparat dafuer.
ATE48477T1 (de) 1984-09-11 1989-12-15 Partec Ag Verfahren und vorrichtung zur sortierung von mikroskopischen partikeln.
US4661913A (en) 1984-09-11 1987-04-28 Becton, Dickinson And Company Apparatus and method for the detection and classification of articles using flow cytometry techniques
US4598408A (en) 1984-10-22 1986-07-01 Trw Inc. High extraction efficiency cylindrical ring resonator
SU1267231A1 (ru) 1984-11-21 1986-10-30 Ленинградский Институт Ядерной Физики Им.Б.П.Константинова Проточный цитофлуориметр-сортировщик клеток
JPS61139747A (ja) 1984-12-12 1986-06-27 Canon Inc 粒子解析装置
FR2574656B1 (fr) 1984-12-13 1988-08-05 Cassou Robert Sonde gynecologique notamment pour l'injection de semence ou d'embryons dans la cavite des animaux, tels que les juments
FR2575063B1 (fr) 1984-12-21 1988-07-01 Cassou Robert Sonde gynecologique pour insemination artificielle, notamment pour porcins
JPS61159135A (ja) 1984-12-31 1986-07-18 Canon Inc 粒子解析装置
SU1260778A1 (ru) 1985-01-31 1986-09-30 Центральный научно-исследовательский рентгено-радиологический институт Устройство дл флуоресцентного анализа отдельных микрочастиц в потоке
FR2577317B1 (fr) * 1985-02-08 1987-03-06 Inst Rech Hydrologique Appareil de mesure de la turbidite d'un liquide en flux continu.
US4702598A (en) 1985-02-25 1987-10-27 Research Corporation Flow cytometer
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1250808A (en) 1985-04-29 1989-03-07 David W. Dresser Semen sexing
US4662742A (en) 1985-05-10 1987-05-05 Becton, Dickinson And Company Scatter/fluorescene beam splitter in a flow cytometry apparatus
JPS61294334A (ja) 1985-06-21 1986-12-25 Canon Inc 粒子解析装置
US4877965A (en) 1985-07-01 1989-10-31 Diatron Corporation Fluorometer
USRE34782E (en) 1985-07-01 1994-11-08 Diatron Corporation Fluorometer
US4744090A (en) 1985-07-08 1988-05-10 Trw Inc. High-extraction efficiency annular resonator
NO156916C (no) 1985-07-10 1987-12-16 Harald B Steen Stroemningskammer for vaeskestroemsfotometer.
NO156917C (no) 1985-07-16 1987-12-16 Harald B Steen Anordning for maaling av biologiske cellers lysspredning i vaeskestroemsfotometere.
US4989977A (en) 1985-07-29 1991-02-05 Becton, Dickinson And Company Flow cytometry apparatus with improved light beam adjustment
US4794086A (en) 1985-11-25 1988-12-27 Liquid Air Corporation Method for measurement of impurities in liquids
US4770992A (en) 1985-11-27 1988-09-13 Den Engh Gerrit J Van Detection of specific DNA sequences by flow cytometry
US4999283A (en) * 1986-01-10 1991-03-12 University Of Kentucky Research Foundation Method for x and y spermatozoa separation
US5447841A (en) 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US5756696A (en) 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
JPS62220833A (ja) * 1986-03-22 1987-09-29 Sigma Tec:Kk 光散乱式微粒子センサ
US4710635A (en) 1986-04-14 1987-12-01 Becton, Dickinson And Company Dual laser excitation from single laser source
NL8601000A (nl) 1986-04-21 1987-11-16 Jan Greve T H Twente Afdeling Het gebruik van gepolariseerd licht in stromingscytometrie.
US5336217A (en) 1986-04-24 1994-08-09 Institut National De La Sante Et De La Recherche Medicale (Insepm) Process for treatment by irradiating an area of a body, and treatment apparatus usable in dermatology for the treatment of cutaneous angio dysplasias
US4790653A (en) 1986-05-22 1988-12-13 Becton Dickinson And Company Housing for a flow cytometry apparatus with particle unclogging feature
JPS62274238A (ja) 1986-05-22 1987-11-28 ベクトン・デイツキンソン・アンド・カンパニ− フロ−サイトメトリ−装置に用いる光学的結合用ゲル
US4786165A (en) 1986-07-10 1988-11-22 Toa Medical Electronics Co., Ltd. Flow cytometry and apparatus therefor
US4867908A (en) 1986-08-29 1989-09-19 Becton, Dickinson And Company Method and materials for calibrating flow cytometers and other analysis instruments
US4704891A (en) 1986-08-29 1987-11-10 Becton, Dickinson And Company Method and materials for calibrating flow cytometers and other analysis instruments
FR2609885B1 (fr) 1987-01-22 1989-04-14 Cassou Robert Instrument pour l'insemination artificielle, le transfert d'embryons ou le prelevement de liquides folliculaires chez les mammiferes
US4780451B1 (en) 1987-01-23 1995-04-04 Asua International Inc Composition and method for producing superovulation in cattle
US5162306A (en) 1987-01-23 1992-11-10 Donaldson Lloyd E Composition and method for producing superovulation in mammals
EP0279000B1 (de) 1987-02-17 1993-07-21 Ratcom, Inc. Durchflusszytometrie
US4764013A (en) 1987-03-23 1988-08-16 The United States Of America As Represented By The United States Department Of Energy Interferometric apparatus and method for detection and characterization of particles using light scattered therefrom
US4765737A (en) 1987-03-30 1988-08-23 Cornell Research Foundation Cell size measurements using light in flow cytometry and cell sorting
EP0286088B1 (de) 1987-04-08 1994-09-14 Hitachi, Ltd. Vorrichtung mit einer scheideförmigen Durchflusszelle
US5021244A (en) 1988-12-06 1991-06-04 Cytogam, Inc. Sex-associated membrane antibodies and their use for increasing the probability that offspring will be of a desired sex
US5346990A (en) 1987-04-08 1994-09-13 Cytogam, Inc. Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
JPS63262565A (ja) 1987-04-20 1988-10-28 Hitachi Ltd フロ−セル
EP0289200B2 (de) 1987-04-27 1998-07-22 Fritz K. Preikschat Vorrichtung und Verfahren zur Untersuchung von Teilchen
EP0289677A3 (de) 1987-04-27 1989-05-10 Fritz K. Preikschat Einrichtung und Verfahren zum Untersuchen von Teilchen
FR2614626B1 (fr) * 1987-04-30 1989-07-21 Ranoux Claude Conteneur pour fecondation des ovocytes et replacement des embryons chez l'homme et l'animal
JP2642632B2 (ja) 1987-07-03 1997-08-20 株式会社日立製作所 微粒子計測装置および微粒子計測方法
GB8716285D0 (en) 1987-07-10 1987-08-19 Medical Res Council Light collecting device
US4979093A (en) 1987-07-16 1990-12-18 Cavro Scientific Instruments XYZ positioner
US4987539A (en) * 1987-08-05 1991-01-22 Stanford University Apparatus and method for multidimensional characterization of objects in real time
US4796788A (en) 1987-08-26 1989-01-10 Liqui-Box Corporation Bag-in-box packaging and dispensing of substances which will not readily flow by gravity
US4758729A (en) 1987-08-28 1988-07-19 Spectra-Physics, Inc. Apparatus and method for measuring the included angle of a reflective cone
DE3832901A1 (de) 1987-10-02 1989-04-20 Hitachi Ltd Teilchenmessvorrichtung
US4793705A (en) 1987-10-07 1988-12-27 The United States Of America As Represented By The United States Department Of Energy Single molecule tracking
US4831385A (en) 1987-10-14 1989-05-16 Burlington Industries, Inc. Vacuum tray fluid-jet start-up system
US4980277A (en) 1987-10-16 1990-12-25 Cultor Ltd. Cryoprotectant solution and method
US5712807A (en) 1987-10-21 1998-01-27 Bangham; James Andrew Pulse analyzing method and apparatus
US5789155A (en) 1987-10-30 1998-08-04 California Institute Of Technology Process for identifying nucleic acids and triple helices formed thereby
GB8726305D0 (en) 1987-11-10 1987-12-16 Secr Defence Portable particle analysers
US4845025A (en) 1987-11-10 1989-07-04 Coulter Corporation Biological sample mixing apparatus and method
EP0316173A1 (de) 1987-11-10 1989-05-17 The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Vorrichtung zur Überwachung von Teilchen
GB8726304D0 (en) 1987-11-10 1987-12-16 Secr Defence Particle asymmetry analyser
US5040890A (en) 1987-11-25 1991-08-20 Becton, Dickinson And Company Sheathed particle flow controlled by differential pressure
US4988619A (en) * 1987-11-30 1991-01-29 United States Department Of Energy Flow cytometry apparatus
US4887721A (en) 1987-11-30 1989-12-19 The United States Of America As Represented By The United States Department Of Energy Laser particle sorter
US4936465A (en) 1987-12-07 1990-06-26 Zoeld Tibor Method and apparatus for fast, reliable, and environmentally safe dispensing of fluids, gases and individual particles of a suspension through pressure control at well defined parts of a closed flow-through system
US5219729A (en) 1988-02-25 1993-06-15 Serono Laboratories, Inc. Fertility assay
US5622820A (en) * 1988-03-10 1997-04-22 City Of Hope Method for amplification and detection of RNA and DNA sequences
US4836038A (en) 1988-03-18 1989-06-06 Aim Instruments Ltd. Automated sampler-injector apparatus and method for sampling a quantity of sample and testing portions of said quantity
US5057413A (en) 1988-06-13 1991-10-15 Becton, Dickinson And Company Method for discriminating between intact and damaged cells in a sample
JPH0213830A (ja) 1988-06-30 1990-01-18 Canon Inc 粒子測定装置
US5070080A (en) 1988-08-10 1991-12-03 Fahim Mostafa S Method of inhibiting generation, maturation, motility and viability of sperm with minerals in bioavailable form
JPH0718785B2 (ja) 1988-09-19 1995-03-06 株式会社日立製作所 フローセル装置
JP2635126B2 (ja) 1988-09-30 1997-07-30 東亜医用電子株式会社 核の分葉指数を求めるための粒子分析装置及び方法
JP2635125B2 (ja) 1988-09-30 1997-07-30 東亜医用電子株式会社 核の分葉指数を求めるための粒子分析装置及び方法
JPH02168160A (ja) 1988-12-22 1990-06-28 Omron Tateisi Electron Co 細胞選別装置
US5726009A (en) 1989-03-20 1998-03-10 Anticancer, Inc. Native-state method and system for determining viability and proliferative capacity of tissues in vitro
JPH02289808A (ja) 1989-04-28 1990-11-29 Olympus Optical Co Ltd 照明光学系
US4981580A (en) 1989-05-01 1991-01-01 Coulter Corporation Coincidence arbitration in a flow cytomery sorting system
WO1990013303A1 (en) 1989-05-10 1990-11-15 The United States Of America, Represented By The Secretary, United States Department Of Commerce Method to preselect the sex of offspring
US4942305A (en) 1989-05-12 1990-07-17 Pacific Scientific Company Integrating sphere aerosol particle detector
WO1990013315A1 (en) 1989-05-12 1990-11-15 Cytogam, Inc. Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
FR2647668A1 (fr) 1989-06-06 1990-12-07 Medizin Labortechnik Veb K Pipette de transfert pour embryons
US5055393A (en) 1989-06-13 1991-10-08 Salk Institute Biotechnology/Industrial Associates, Inc. Prenatal sex determination of bovine cells using male-specific oligonucleotides
US4954715A (en) 1989-06-26 1990-09-04 Zoeld Tibor Method and apparatus for an optimized multiparameter flow-through particle and cell analyzer
JPH0353164A (ja) 1989-07-20 1991-03-07 Canon Inc サンプル供給装置及びこれを用いたサンプル測定装置
US5098657A (en) 1989-08-07 1992-03-24 Tsi Incorporated Apparatus for measuring impurity concentrations in a liquid
US5030002A (en) 1989-08-11 1991-07-09 Becton, Dickinson And Company Method and apparatus for sorting particles with a moving catcher tube
US5005981A (en) 1989-09-08 1991-04-09 Becton, Dickinson And Company Apparatus for method for causing vortices in a test tube
US5215376A (en) 1989-09-08 1993-06-01 Becton, Dickinson And Company Method for causing vortices in a test tube
DE69014507T2 (de) 1989-09-13 1995-04-13 Tiyoda Seisakusho Koushoku Kk Gerät zur Zellenvorbehandlung für Durchfluss-Zytometrie.
JP2808321B2 (ja) * 1989-09-19 1998-10-08 東亜医用電子株式会社 細胞分析方法及び装置
US5170064A (en) * 1989-09-29 1992-12-08 Atomic Energy Of Canada Limited Infrared-based gas detector using a cavity having elliptical reflecting surface
US5072382A (en) 1989-10-02 1991-12-10 Kamentsky Louis A Methods and apparatus for measuring multiple optical properties of biological specimens
US5275787A (en) 1989-10-04 1994-01-04 Canon Kabushiki Kaisha Apparatus for separating or measuring particles to be examined in a sample fluid
EP0422616B1 (de) 1989-10-11 1996-02-07 Canon Kabushiki Kaisha Gerät und Verfahren zur Trennung von Teilchen aus flüssigkeitssuspendierten Teilchen in Zusammenhang mit deren Eigenschaften
JPH03140840A (ja) 1989-10-26 1991-06-14 Hitachi Ltd 流動細胞分析装置
FR2653885B1 (fr) 1989-10-27 1994-01-14 Abx Appareil pour le comptage et la determination d'au moins une sous-population leucocytaire.
US5034613A (en) 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
US5101978A (en) 1989-11-27 1992-04-07 The United States Of America As Represented By The Secretary Of The Army Fluidic sorting device for two or more materials suspended in a fluid
AU647741B2 (en) 1989-12-01 1994-03-31 Regents Of The University Of California, The Methods and compositions for chromosome-specific staining
US5274240A (en) 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
EP0448931B1 (de) 1990-01-26 1996-04-03 Canon Kabushiki Kaisha Verfahren zur Messung einer Spezies unter Verwendung von Fluoreszenzlicht
JP3049254B2 (ja) 1990-02-08 2000-06-05 シスメックス株式会社 ２種類の光源を備えた光学式粒子分析装置
IL93634A0 (en) 1990-03-05 1990-12-23 Galai Lab Ltd Particle size analyzer
EP0446509A1 (de) 1990-03-15 1991-09-18 Panayiotis M. Zavos Sperma-Säulenfilter
US5153117A (en) 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method
US5492534A (en) 1990-04-02 1996-02-20 Pharmetrix Corporation Controlled release portable pump
US5150313A (en) 1990-04-12 1992-09-22 Regents Of The University Of California Parallel pulse processing and data acquisition for high speed, low error flow cytometry
US5076472A (en) 1990-06-13 1991-12-31 Becton, Dickinson And Company Cleaning cycle for flow cytometers
US5087295A (en) 1990-06-13 1992-02-11 Becton Dickinson And Company Cleaning cycle for flow cytometers
JPH0716392B2 (ja) 1990-06-20 1995-03-01 株式会社ピーシーシーテクノロジー 細胞融合及び融合細胞選別システム
JPH0710226B2 (ja) 1990-06-20 1995-02-08 株式会社ピーシーシーテクノロジー プロトプラスト攪拌装置並びにそれを含む細胞融合装置及びフローサイトメーター装置
US5160974A (en) 1990-06-25 1992-11-03 Flow Science, Inc. Closed sample cell for use in flow cytometry
JPH04126065A (ja) 1990-06-25 1992-04-27 Saburo Okonogi 食品素材の棒状体成型装置
US5559032A (en) 1990-06-29 1996-09-24 Pomeroy; Patrick C. Method and apparatus for post-transfer assaying of material on solid support
US5366888A (en) 1990-07-09 1994-11-22 Amrad Corporation Limited Enhanced maintenance of pregnancy using leukaemia inhibitory factor in embryo culturing
JP2939647B2 (ja) 1990-07-24 1999-08-25 シスメックス株式会社 フローイメージングサイトメータにおける自動焦点調整方法
IE76732B1 (en) 1990-08-07 1997-11-05 Becton Dickinson Co One step test for absolute counts
US5259593A (en) 1990-08-30 1993-11-09 University Of Southern California Apparatus for droplet stream manufacturing
JPH04115136A (ja) 1990-09-05 1992-04-16 Hitachi Ltd 粒子計測装置
JPH04126080A (ja) 1990-09-14 1992-04-27 Juzo Udaka 耐熱性キシロースイソメラーゼの製造方法
JPH04126064A (ja) 1990-09-14 1992-04-27 Nitto Shokai:Kk 二重包餡食品の製造法
JP2957246B2 (ja) 1990-09-14 1999-10-04 大和化成株式会社 微生物起源カルボキシペプチダーゼｂ様酵素
US5132548A (en) * 1990-09-14 1992-07-21 High Yield Technology High sensitivity, large detection area particle sensor for vacuum applications
US5204884A (en) 1991-03-18 1993-04-20 University Of Rochester System for high-speed measurement and sorting of particles
US5273527A (en) 1992-05-12 1993-12-28 Ovamed Corporation Delivery catheter
US5663048A (en) 1990-10-04 1997-09-02 University Of Calgary Y-chromosome specific polynucleotide probes for prenatal sexing
US5840482A (en) * 1990-10-10 1998-11-24 The Regents Of The University Of California Y chromosome specific nucleic acid probe and method for determining the Y chromosome in situ
WO1992008120A1 (en) 1990-10-29 1992-05-14 Macquarie University Pulsed laser flow cytometry
US5116125A (en) 1990-10-31 1992-05-26 Biophos Medical Ab Fertility analyzer
DE69013366T2 (de) 1990-10-31 1995-04-20 Biophos Medical Ab Fruchtbarkeitsanalysegerät.
JP2874746B2 (ja) 1990-11-22 1999-03-24 シスメックス株式会社 フローイメージングサイトメータにおけるフローセル機構
US5991028A (en) 1991-02-22 1999-11-23 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for cell classification
JPH0734012B2 (ja) 1991-02-27 1995-04-12 東亜医用電子株式会社 フローイメージサイトメータ
JP3121849B2 (ja) 1991-02-27 2001-01-09 シスメックス株式会社 フローイメージサイトメータ
US5144224A (en) 1991-04-01 1992-09-01 Larsen Lawrence E Millimeter wave flow cytometer
US5199576A (en) 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
EP0515211A3 (en) 1991-05-23 1993-04-07 Becton Dickinson And Company Apparatus and method for phase resolved fluorescence lifetimes of independent and varying amplitude pulses
DE9107792U1 (de) * 1991-06-25 1991-09-12 Labotect-Labor-Technik, Goettingen, Gmbh, 3406 Bovenden, De
FR2678506B1 (fr) 1991-07-01 2000-03-10 Claude Ranoux Procede de fecondation en cycle spontane.
US5548661A (en) 1991-07-12 1996-08-20 Price; Jeffrey H. Operator independent image cytometer
US5412466A (en) 1991-07-26 1995-05-02 Toa Medical Electronics Co., Ltd. Apparatus for forming flattened sample flow for analyzing particles
US5488469A (en) 1991-08-30 1996-01-30 Omron Corporation Cell analyzing apparatus
DE69230902D1 (de) 1991-08-30 2000-05-18 Omron Tateisi Electronics Co Vorrichtung zur Zellenanalyse
US5548395A (en) 1991-09-20 1996-08-20 Toa Medical Electronics Co., Ltd. Particle analyzer
US5578449A (en) 1991-10-03 1996-11-26 Hilding Ohlsson, S.A. Procedure for the sex determination of embryos in mammals especially applied to bovine embryos
IT1253226B (it) 1991-10-24 1995-07-11 Piero Serra Catetere per l'introduzione o l'aspirazione di liquidi di diversa natura in animali particolarmente per trattamenti ginecologici in bovini, equini e simili
US5919621A (en) 1991-10-24 1999-07-06 Brown; David B. Methods for diagnosing human male infertility
JP3212647B2 (ja) 1991-10-24 2001-09-25 シスメックス株式会社 イメージングフローサイトメータ
US5866344A (en) 1991-11-15 1999-02-02 Board Of Regents, The University Of Texas System Antibody selection methods using cell surface expressed libraries
US5370842A (en) 1991-11-29 1994-12-06 Canon Kabushiki Kaisha Sample measuring device and sample measuring system
JP2593021B2 (ja) 1991-12-13 1997-03-19 伊藤ハム株式会社 ウシ胚の性の識別方法
JP3130628B2 (ja) 1992-01-30 2001-01-31 シスメックス株式会社 粒子判定装置
US5400179A (en) 1992-02-18 1995-03-21 Asahi Kogaku Kogyo Kabushiki Kaisha Optical multilayer thin film and beam splitter
DE69321748T2 (de) 1992-02-20 1999-06-17 Canon Kk Verfahren und Messapparatur zur Handhabung von Teilchen
AU3508993A (en) 1992-02-21 1993-09-13 Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Analysis of particle characteristics
US5558998A (en) 1992-02-25 1996-09-24 The Regents Of The Univ. Of California DNA fragment sizing and sorting by laser-induced fluorescence
US6120735A (en) 1992-02-26 2000-09-19 The Ohio States University Fractional cell sorter
JP3203624B2 (ja) * 1992-04-30 2001-08-27 株式会社島津製作所 レーザー蛍光検出装置
US5298967A (en) 1992-06-02 1994-03-29 Pacific Scientific Company Measurement of concentrations of dissolved solvent
JP3145486B2 (ja) 1992-06-12 2001-03-12 シスメックス株式会社 イメージングフローサイトメータ
PL307164A1 (en) 1992-07-13 1995-05-02 Pall Corp Automatic system for and method of processing biological fluids
JP3215175B2 (ja) 1992-08-10 2001-10-02 シスメックス株式会社 粒子分析装置
US5315122A (en) * 1992-08-25 1994-05-24 Becton, Dickinson And Company Apparatus and method for fluorescent lifetime measurement
WO1994005775A1 (en) 1992-09-03 1994-03-17 Systemix, Inc. High speed flow cytometric separation of viable mammalian cells
US5466572A (en) 1992-09-03 1995-11-14 Systemix, Inc. High speed flow cytometric separation of viable cells
US5736410A (en) * 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US5275933A (en) 1992-09-25 1994-01-04 The Board Of Trustees Of The Leland Stanford Junior University Triple gradient process for recovering nucleated fetal cells from maternal blood
US5311290A (en) 1992-09-30 1994-05-10 Pulp And Paper Research Institute Of Canada Imaging apparatus and method of fiber analysis
US5371585A (en) 1992-11-10 1994-12-06 Pacific Scientific Company Particle detecting instrument with sapphire detecting cell defining a rectangular flow path
US5359907A (en) 1992-11-12 1994-11-01 Horiba Instruments, Inc. Method and apparatus for dry particle analysis
US5395588A (en) 1992-12-14 1995-03-07 Becton Dickinson And Company Control of flow cytometer having vacuum fluidics
FR2699678A1 (fr) 1992-12-23 1994-06-24 Unceia Procédé cytométrique de séparation de spermatozoïdes X et Y en fonction de leur contenu en ADN.
JPH08505741A (ja) 1993-01-16 1996-06-18 バンガム，ジェイムズ・アンドリュー 信号処理システム
JP2525713B2 (ja) 1993-01-19 1996-08-21 農林水産省畜産試験場長 低分子チオ―ル化合物を用いた牛胚の培養法および輸送法
US5467189A (en) 1993-01-22 1995-11-14 Venturedyne, Ltd. Improved particle sensor and method for assaying a particle
JP3052665B2 (ja) 1993-01-26 2000-06-19 株式会社日立製作所 フローセル装置
CA2113957A1 (en) 1993-01-29 1994-07-30 University Of Guelph Nucleotide sequences for bovine sex determination
US5453575A (en) 1993-02-01 1995-09-26 Endosonics Corporation Apparatus and method for detecting blood flow in intravascular ultrasonic imaging
JPH08506664A (ja) 1993-02-01 1996-07-16 セック，リミテッド Ｄｎａ配列決定の方法および装置
US5367474A (en) 1993-02-08 1994-11-22 Coulter Corporation Flow cytometer
US5556764A (en) 1993-02-17 1996-09-17 Biometric Imaging, Inc. Method and apparatus for cell counting and cell classification
US5547849A (en) 1993-02-17 1996-08-20 Biometric Imaging, Inc. Apparatus and method for volumetric capillary cytometry
US5563059A (en) 1993-02-23 1996-10-08 Genentech, Inc. Use of human inhibin and human activin to increase the number of mature primate oocytes
DE69418131D1 (de) 1993-03-01 1999-06-02 Gen Signal Corp Vorrichtung zur erzeugung einer einstellbaren ringförmigen beleuchtung für einen photolithograpischen projektionsapparat
NO930980L (no) 1993-03-18 1994-09-19 Flowtech As Optisk konfigurasjon for væskeströmcytofotometer
US5658751A (en) 1993-04-13 1997-08-19 Molecular Probes, Inc. Substituted unsymmetrical cyanine dyes with selected permeability
US5494795A (en) * 1993-05-05 1996-02-27 The United States Of America As Represented By The Secretary Of The Navy Specific oligonucleotide primers for detection of pathogenic campylobacter bacteria by polymerase chain reaction
EP0627643B1 (de) 1993-06-03 1999-05-06 Hamamatsu Photonics K.K. Optisches Laser-Abtastsystem mit Axikon
US5439578A (en) 1993-06-03 1995-08-08 The Governors Of The University Of Alberta Multiple capillary biochemical analyzer
JPH08501718A (ja) * 1993-06-04 1996-02-27 クワハック・インターナショナル・カンパニー・リミテッド 人工受精及び受精卵移植装置
NO932088L (no) 1993-06-08 1995-01-05 Oddbjoern Gjelsnes Anordning for anvendelse ved væskeströmscytometri
US5464581A (en) 1993-08-02 1995-11-07 The Regents Of The University Of California Flow cytometer
US5483469A (en) 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer
US6328071B1 (en) 1993-08-06 2001-12-11 Cary Austin Well pressure tank
US5596401A (en) 1993-09-16 1997-01-21 Toa Medical Electronics Co., Ltd. Particle analyzing apparatus using a coherence lowering device
US5503994A (en) * 1993-10-08 1996-04-02 The Board Of Trustees Of The Leland Stanford Junior University System for sample detection with compensation for difference in sensitivity to detection of components moving at different velocities
US5480774A (en) * 1993-10-14 1996-01-02 A/F Protein, Inc. Determination of genomic sex in salmonids
JP3290786B2 (ja) 1993-11-26 2002-06-10 シスメックス株式会社 粒子分析装置
GB9324938D0 (en) 1993-12-04 1994-01-26 Atomic Energy Authority Uk Aerosol generator
FI96452C (fi) 1994-01-26 1996-06-25 Pekka Haenninen Menetelmä väriaineiden virittämiseksi
JP2683297B2 (ja) 1994-02-28 1997-11-26 スンキョン インダストリーズ カンパニー リミテッド ピリミジンアシクロヌクレオシド誘導体
US5475487A (en) 1994-04-20 1995-12-12 The Regents Of The University Of California Aqueous carrier waveguide in a flow cytometer
DE4414940C2 (de) 1994-04-28 1998-07-02 Pekka Haenninen Lumineszenz-Rastermikroskop mit zwei Photonen Anregung
US5595866A (en) 1994-05-27 1997-01-21 Methodist Hospital Of Indiana, Inc. Step-wise method to remove cryoprotectant from sperm
DE4419894A1 (de) * 1994-06-07 1995-12-14 Gip Medizin Technik Gmbh Endoskopische Punktionsnadelvorrichtung
EP0687956B2 (de) 1994-06-17 2005-11-23 Carl Zeiss SMT AG Beleuchtungseinrichtung
US5601234A (en) 1994-08-01 1997-02-11 Abbott Laboratories Fluid nozzle and method of introducing a fluid
US5891734A (en) * 1994-08-01 1999-04-06 Abbott Laboratories Method for performing automated analysis
JP3375203B2 (ja) 1994-08-08 2003-02-10 シスメックス株式会社 細胞分析装置
FR2723735B1 (fr) 1994-08-18 1996-10-31 Abx Sa Boitier a branchement automatique pour distribution de reactifs dans un appareil notamment un analyseur hematologique.
US20020186874A1 (en) 1994-09-07 2002-12-12 Jeffrey H. Price Method and means for image segmentation in fluorescence scanning cytometry
US5790692A (en) 1994-09-07 1998-08-04 Jeffrey H. Price Method and means of least squares designed filters for image segmentation in scanning cytometry
US5540020A (en) 1994-09-26 1996-07-30 Santini; Daniel E. Building panel
US5700692A (en) 1994-09-27 1997-12-23 Becton Dickinson And Company Flow sorter with video-regulated droplet spacing
IL115327A (en) 1994-10-07 2000-08-13 Bayer Ag Diaphragm pump
US5934885A (en) 1994-10-07 1999-08-10 Bayer Corporation Reagent pump assembly
US5643796A (en) 1994-10-14 1997-07-01 University Of Washington System for sensing droplet formation time delay in a flow cytometer
US5602039A (en) * 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
US6861265B1 (en) 1994-10-14 2005-03-01 University Of Washington Flow cytometer droplet formation system
US5602349A (en) * 1994-10-14 1997-02-11 The University Of Washington Sample introduction system for a flow cytometer
WO1996012171A2 (en) 1994-10-14 1996-04-25 University Of Washington High speed flow cytometer droplet formation system
JP3347495B2 (ja) 1994-11-14 2002-11-20 シスメックス株式会社 粒子分析装置
US5495719A (en) 1994-11-14 1996-03-05 Gray, Jr.; Carl O. Method of preserving spermatozoa
US5514537A (en) * 1994-11-28 1996-05-07 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Process and apparatus for sorting spermatozoa
WO1996018205A1 (en) 1994-12-08 1996-06-13 Molecular Dynamics, Inc. Fluorescence imaging system employing a macro scanning objective
US5632754A (en) * 1994-12-23 1997-05-27 Devices For Vascular Intervention Universal catheter with interchangeable work element
DE69533469T2 (de) 1994-12-26 2005-09-22 Sysmex Corp. Durchflusszytometer
US5835262A (en) 1994-12-28 1998-11-10 Research Development Corporation Of Japan Multi-wavelength optical microscope
FI98765C (fi) * 1995-01-16 1997-08-11 Erkki Soini Virtaussytometrinen menetelmä ja laite
US5608519A (en) 1995-03-20 1997-03-04 Gourley; Paul L. Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells
US5793485A (en) 1995-03-20 1998-08-11 Sandia Corporation Resonant-cavity apparatus for cytometry or particle analysis
US5620842A (en) 1995-03-29 1997-04-15 Becton Dickinson And Company Determination of the number of fluorescent molecules on calibration beads for flow cytometry
US5786560A (en) 1995-03-31 1998-07-28 Panasonic Technologies, Inc. 3-dimensional micromachining with femtosecond laser pulses
US5699152A (en) * 1995-04-03 1997-12-16 Alltrista Corporation Electro-optical inspection system and method
US5682038A (en) 1995-04-06 1997-10-28 Becton Dickinson And Company Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations
US5528045A (en) 1995-04-06 1996-06-18 Becton Dickinson And Company Particle analyzer with spatially split wavelength filter
US5641457A (en) 1995-04-25 1997-06-24 Systemix Sterile flow cytometer and sorter with mechanical isolation between flow chamber and sterile enclosure
US5687727A (en) 1995-05-01 1997-11-18 Danforth Biomedical Incorporated Catheter adaptor with slitting blade and improved manual control and method of use
WO1996035384A1 (en) 1995-05-09 1996-11-14 Curators Of The University Of Missouri A system for introducing a fluid into the uterus of an animal
FR2734637B1 (fr) 1995-05-24 1997-08-14 Abx Sa Dispositif d'inspection optique d'un fluide, notamment pour analyses hematologiques
US5798276A (en) 1995-06-07 1998-08-25 Molecular Probes, Inc. Reactive derivatives of sulforhodamine 101 with enhanced hydrolytic stability
US5650847A (en) 1995-06-14 1997-07-22 Erkki Soini Method and device for determination of parameters of individual microparticles
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US5589457A (en) 1995-07-03 1996-12-31 Ausa International, Inc. Process for the synchronization of ovulation
US6411835B1 (en) 1997-01-13 2002-06-25 Medispectra, Inc. Spectral volume microprobe arrays
DE69634449T2 (de) 1995-08-11 2006-01-05 University Of Guelph, Guelph Verfahren zum identifizieren von geschlechtsspezifischen und speziesspezifischen molekülen, mit verfahren identifizierte moleküle und verwendung der moleküle
EP0862432A4 (de) 1995-09-06 2003-03-19 Univ New York State Res Found Zwei-photonen nach oben konvertierende farbstoffe und deren anwendungen
DE19533092A1 (de) 1995-09-07 1997-03-13 Basf Ag Vorrichtung zur parallelisierten Zweiphotonen-Fluoreszenz-Korrelations-Spektroskopie (TPA-FCS) und deren Verwendung zum Wirkstoff-Screening
US6329158B1 (en) 1995-09-15 2001-12-11 Becton Dickinson And Company Use of dimly fluorescing nucleic acid dyes in the identification of nucleated cells
US6040139A (en) 1995-09-19 2000-03-21 Bova; G. Steven Laser cell purification system
US5726751A (en) 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer
US5780230A (en) 1995-10-06 1998-07-14 Coriell Institute For Medical Research Compositions and methods for human sperm activation and quantitative assessment of human sperm genome replication
US5736330A (en) 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
DE69637625D1 (de) 1995-10-19 2008-09-18 Bio Origyn Llc Methoden und zusammensetzungen, die das ueberleben und die funktion von keimbahnzellen und embryonen verbessern
US6117068A (en) 1995-10-19 2000-09-12 Elite Genetics, Inc Artificial insemination system
ES2186732T3 (es) 1995-11-09 2003-05-16 Medical Res Council Uso de medio cyb para el transporte y almacenamiento de esperma.
DE19549015C1 (de) 1995-12-28 1997-04-03 Siemens Ag Verfahren und Anordnung zur Überwachung eines abreißenden Flüssigkeitstrahls
JP3584108B2 (ja) 1996-01-08 2004-11-04 キヤノン株式会社 レンズ鏡筒
US6641708B1 (en) 1996-01-31 2003-11-04 Board Of Regents, The University Of Texas System Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation
WO1997029354A1 (de) 1996-02-05 1997-08-14 Bayer Aktiengesellschaft Verfahren und vorrichtung zum sortieren und zur gewinnung von planar ausgebrachten biologischen objekten wie biologische zellen bzw. zellorganellen, histologischen schnitten, chromosomenteilchen etc. mit laserstrahlen
BR9600722A (pt) 1996-02-14 1997-12-30 Jorge Antonio Rodrigues Claro Bomba de infusão para contidos em bolsas plásticas flexíveis
WO1997030338A1 (en) 1996-02-16 1997-08-21 Inphocyte, Inc. System and method for rapid analysis of cells using spectral cytometry
JP3127111B2 (ja) 1996-02-22 2001-01-22 株式会社日立製作所 フロー式粒子画像解析方法および装置
US6143901A (en) 1996-07-31 2000-11-07 Genesoft, Inc. Complex formation between dsDNA and pyrrole imidazole polyamides
US6090947A (en) 1996-02-26 2000-07-18 California Institute Of Technology Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
US5895922A (en) * 1996-03-19 1999-04-20 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
US5701012A (en) 1996-03-19 1997-12-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
US5747349A (en) 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
JP3640461B2 (ja) 1996-04-03 2005-04-20 シスメックス株式会社 粒子分析装置
US5707808A (en) 1996-04-15 1998-01-13 The Regents Of The University Of California Optical selection and collection of DNA fragments
BR9710836A (pt) 1996-04-25 2000-10-24 Spectrametrix Inc Ensaio de analitos usando marcas em partìculas
WO1997043620A1 (en) 1996-05-15 1997-11-20 International Remote Imaging Systems, Inc. Selectively emphasizing particles of interest from a fluid sample for analysis
JP2963393B2 (ja) * 1996-06-14 1999-10-18 浜松ホトニクス株式会社 光電子増倍管用電圧分割回路
US5846737A (en) 1996-07-26 1998-12-08 Molecular Probes, Inc. Conjugates of sulforhodamine fluorophores with enhanced fluorescence
US5909278A (en) 1996-07-29 1999-06-01 The Regents Of The University Of California Time-resolved fluorescence decay measurements for flowing particles
EP0822401A3 (de) 1996-07-30 1999-05-06 Bayer Corporation Hydraulisches System für hämatologische Analysevorrichtung
US6074827A (en) 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US5844685A (en) 1996-07-30 1998-12-01 Bayer Corporation Reference laser beam sampling apparatus
US6042249A (en) 1996-07-30 2000-03-28 Bayer Corporation Illuminator optical assembly for an analytical instrument and methods of alignment and manufacture
US5872627A (en) 1996-07-30 1999-02-16 Bayer Corporation Method and apparatus for detecting scattered light in an analytical instrument
US5883378A (en) 1996-07-30 1999-03-16 Bayer Corporation Apparatus and methods for transmitting electrical signals indicative of optical interactions between a light beam and a flowing suspension of particles
US5745308A (en) 1996-07-30 1998-04-28 Bayer Corporation Methods and apparatus for an optical illuminator assembly and its alignment
US5719667A (en) 1996-07-30 1998-02-17 Bayer Corporation Apparatus for filtering a laser beam in an analytical instrument
ES2328423T3 (es) 1996-07-30 2009-11-12 Siemens Healthcare Diagnostics Inc. Sistema optico para un instrumento de hematologia analitica.
US5998140A (en) 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
US5804436A (en) 1996-08-02 1998-09-08 Axiom Biotechnologies, Inc. Apparatus and method for real-time measurement of cellular response
CA2261148A1 (en) 1996-08-07 1998-02-12 Robert Slovak Additive dispensing apparatus
JP2002503334A (ja) 1996-09-04 2002-01-29 テクニカル ユニバーシティ オブ デンマーク 粒子の分離と分析用のマイクロフローシステム
EP0929300B1 (de) 1996-09-06 2004-05-26 Medarex, Inc. Cyanidinzusammensetzungen und deren therapeutische und diagnostische verwendungen
US5873254A (en) * 1996-09-06 1999-02-23 Interface Multigrad Technology Device and methods for multigradient directional cooling and warming of biological samples
US6221654B1 (en) 1996-09-25 2001-04-24 California Institute Of Technology Method and apparatus for analysis and sorting of polynucleotides based on size
US5759767A (en) 1996-10-11 1998-06-02 Joseph R. Lakowicz Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids
US6002471A (en) 1996-11-04 1999-12-14 California Institute Of Technology High resolution scanning raman microscope
US5799830A (en) 1996-11-08 1998-09-01 Carroll; David C. Pressure vessel access port
US5696157A (en) 1996-11-15 1997-12-09 Molecular Probes, Inc. Sulfonated derivatives of 7-aminocoumarin
EP1017987B1 (de) 1997-01-31 2005-06-15 The Horticulture And Food Research Institute Of New Zealand Limited Optische vorrichtung und methode
US5874266A (en) 1997-03-27 1999-02-23 Palsson; Bernhard O. Targeted system for removing tumor cells from cell populations
US6534308B1 (en) * 1997-03-27 2003-03-18 Oncosis, Llc Method and apparatus for selectively targeting specific cells within a mixed cell population
US6753161B2 (en) 1997-03-27 2004-06-22 Oncosis Llc Optoinjection methods
GB9707096D0 (en) 1997-04-08 1997-05-28 Smithkline Beecham Plc Novel device
JP2968231B2 (ja) 1997-04-11 1999-10-25 株式会社荏原製作所 空調システム
US6050935A (en) * 1997-05-09 2000-04-18 Biofertec Container assembly for intravaginal fertilization and culture and embryo transfer and method of intravaginal fertilization and culture employing such a container
US6133995A (en) 1997-05-09 2000-10-17 Sysmex Corporation Particle measuring apparatus
JP4754661B2 (ja) 1997-06-09 2011-08-24 ミリポア・コーポレイション 流体サンプル中のミクロ粒子を検出するための方法及び装置
US6139800A (en) 1997-06-23 2000-10-31 Luminex Corporation Interlaced lasers for multiple fluorescence measurement
ES2260809T3 (es) 1997-07-01 2006-11-01 Vlp Watertown Limited Partnership Metodo para la determinacion del sexo de una progenie mamifera.
US6111398A (en) 1997-07-03 2000-08-29 Coulter International Corp. Method and apparatus for sensing and characterizing particles
BR9704313A (pt) 1997-07-08 1999-04-06 Alves Elias Walter Utilização de ig-y de ovo de galinha associado a anticorpos monoclonais contra antigenos sexo especifico na imunosexagem de espermatozóides de bovinos
US5899848A (en) 1997-07-14 1999-05-04 Haubrich; Mark A. Device and process for artificial insemination of animals
US5985216A (en) 1997-07-24 1999-11-16 The United States Of America, As Represented By The Secretary Of Agriculture Flow cytometry nozzle for high efficiency cell sorting
US5876942A (en) * 1997-07-24 1999-03-02 National Science Council Of Republic Of China Process for sexing cow embryos
US5985538A (en) 1997-08-01 1999-11-16 Saint Barnabas Medical Center Cryopreservation and cell culture medium comprising less than 50 mM sodium ions and greater than 100 mM choline salt
US5819948A (en) 1997-08-21 1998-10-13 Van Den Engh; Gerrit J. Particle separating apparatus and method
US6003678A (en) 1997-08-21 1999-12-21 University Of Washington Particle separating apparatus and method
US5880474A (en) 1997-08-29 1999-03-09 Becton Dickinson And Company Multi-illumination-source flow particle analyzer with inter-location emissions crosstalk cancelation
US6395305B1 (en) 1997-09-22 2002-05-28 University Of Guelph Reduction of sperm sensitivity to chilling
US6540895B1 (en) 1997-09-23 2003-04-01 California Institute Of Technology Microfabricated cell sorter for chemical and biological materials
JP3735190B2 (ja) 1997-10-28 2006-01-18 オリンパス株式会社 走査型サイトメータ
US6322901B1 (en) 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
WO1999026186A1 (en) 1997-11-19 1999-05-27 University Of Washington High throughput optical scanner
US6086574A (en) 1997-11-21 2000-07-11 Hyclone Laboratories, Inc. Fluid delivery systems with diptube connector
US5895764A (en) * 1997-11-24 1999-04-20 University Of New Mexico Controlled sheath flow injection cytometry
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US5990479A (en) 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6221671B1 (en) 1997-12-12 2001-04-24 Chemunex S.A. Digital flow cytometer and method
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
EP1058688A4 (de) 1998-02-03 2004-10-06 Xy Inc Spezifische oligonukleotidprimer zur detektion der anwesenheit des männlichen bovinen chromosoms durch eine polymerasekettenreaktion
RU2224992C2 (ru) 1998-02-20 2004-02-27 Кси, Инк. Вибрационная система для проточного цитометра, предназначенного для сортинга
US6746873B1 (en) 1998-02-20 2004-06-08 Xy, Inc. Vibratory system for a sorting flow cytometer
US6154276A (en) 1998-02-23 2000-11-28 The Regents Of The University Of California Waveguide detection of right-angle-scattered light in flow cytometry
US6211477B1 (en) 1998-02-26 2001-04-03 Becton Dickinson And Company Electrostatic deceleration system for flow cytometer
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
US6042025A (en) * 1998-03-13 2000-03-28 Smith Et Al. Two hole dispenser with baffles
JP2002506989A (ja) 1998-03-16 2002-03-05 パルテック パルテーケルツェールゲレーテ ゲーエムベーハー 流体を精確な少量に分配する電子装置
JP3594794B2 (ja) 1998-03-24 2004-12-02 独立行政法人 科学技術振興機構 ナノ秒時間ゲート分光診断装置
US6642018B1 (en) 1998-03-27 2003-11-04 Oncosis Llc Method for inducing a response in one or more targeted cells
EP1068509A4 (de) 1998-03-30 2005-05-25 Bioshaf Durchflusszytometer zur analyse von allgemeinen diagnostischen faktoren in zellen und körperflüssigkeiten
US6175409B1 (en) * 1999-04-02 2001-01-16 Symyx Technologies, Inc. Flow-injection analysis and variable-flow light-scattering methods and apparatus for characterizing polymers
JP3350442B2 (ja) 1998-04-09 2002-11-25 科学技術振興事業団 顕微鏡システム
AU4184099A (en) 1998-05-14 1999-11-29 Luminex Corporation Zero dead time architecture and method for flow cytometer
AU3897999A (en) 1998-05-14 1999-11-29 Luminex Corporation Multi-analyte diagnostic system and computer implemented process for same
EP1046032A4 (de) 1998-05-18 2002-05-29 Univ Washington Patrone zur flüssigkeitsanalyse
ATE530891T1 (de) 1998-05-22 2011-11-15 California Inst Of Techn Miniaturisierter zellsortierer
US6079836A (en) 1998-07-20 2000-06-27 Coulter International Corp. Flow cytometer droplet break-off location adjustment mechanism
DE69942959D1 (de) 1998-07-30 2010-12-30 Xy Llc Pferdesystem für die künstliche Befruchtung ohne chirurgischen Eingriff
US20040107150A1 (en) 1998-07-31 2004-06-03 Chata Biosystems, Inc. Of Colorado Apparatus and method with vessel for containing/transporting a fluent substance
US6729369B2 (en) 1998-07-31 2004-05-04 Chata Biosystems, Inc. Vessel for containing/transporting a fluent substance
DE29813921U1 (de) 1998-08-04 1998-10-08 Kisfeld Alfons Vorrichtung zur Besamung von Tieren, insbesondere Sauen
US6309815B1 (en) 1998-08-07 2001-10-30 University Of Kansas Medical Center Composition and method for preparation, storage and activation of large populations of immotile sperm
WO2000009113A1 (en) 1998-08-17 2000-02-24 Trout William E Use of zeranol to modulate reproductive cycles
DE69937353T2 (de) 1998-08-21 2008-07-17 Union Biometrica, Inc., Somerville Instrument zur analyse und selektiven verteilung von objektproben
US6326144B1 (en) 1998-09-18 2001-12-04 Massachusetts Institute Of Technology Biological applications of quantum dots
US6495333B1 (en) 1998-09-22 2002-12-17 Becton Dickinson And Company Flow cytometric, whole blood dendritic cell immune function assay
US6208411B1 (en) 1998-09-28 2001-03-27 Kla-Tencor Corporation Massively parallel inspection and imaging system
US6707555B1 (en) 1998-10-15 2004-03-16 Sysmex Corporation Optical information measuring apparatus
US6423505B1 (en) 1998-12-03 2002-07-23 Becton Dickinson And Company Methods and reagents for quantitation of HLA-DR and CD11b expression on peripheral blood cells
US7649153B2 (en) 1998-12-11 2010-01-19 International Business Machines Corporation Method for minimizing sample damage during the ablation of material using a focused ultrashort pulsed laser beam
US7116407B2 (en) 1998-12-15 2006-10-03 Union Biometrica, Inc. System for axial pattern analysis of multicellular organisms
US6128133A (en) 1998-12-22 2000-10-03 Lucent Technologies Inc. Optical beamsplitter
EP1018644A2 (de) 1999-01-06 2000-07-12 Bayer Corporation Zähler für Teilchen variabler Rate und Inwendungsverfahren
US20010006416A1 (en) 1999-01-11 2001-07-05 Johnson Paul E. Ribbon flow cytometry apparatus and methods
US6256096B1 (en) 1999-01-11 2001-07-03 Softray Flow cytometry apparatus and method
US6150119A (en) 1999-01-19 2000-11-21 Caliper Technologies Corp. Optimized high-throughput analytical system
US6580504B1 (en) 1999-01-25 2003-06-17 Amnis Corporation Multipass cavity for illumination and excitation of moving objects
US6671044B2 (en) 1999-01-25 2003-12-30 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells in broad flat flow
US6473176B2 (en) 1999-01-25 2002-10-29 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6707551B2 (en) 2000-01-24 2004-03-16 Amnis Corporation Multipass cavity for illumination and excitation of moving objects
US6119465A (en) 1999-02-10 2000-09-19 Mullens; Patrick L. Shipping container for storing materials at cryogenic temperatures
FR2789778B1 (fr) * 1999-02-12 2001-09-14 France Telecom Procede pour associer des references d'acheminement a des paquets de donnees au moyen d'une memoire trie, et routeur de paquets appliquant ce procede
US6323632B1 (en) 1999-08-13 2001-11-27 Coulter International Corp. Solid state RF oscillator-detector for flow cytometer
US6097485A (en) 1999-03-08 2000-08-01 Integrated Waveguides, Inc. Microchip optical transport technology for use in a personal flow cytometer
FR2791645B1 (fr) 1999-04-02 2001-06-15 Valois Sa Echantillon de produit fluide destine a la presse
US6193647B1 (en) 1999-04-08 2001-02-27 The Board Of Trustees Of The University Of Illinois Microfluidic embryo and/or oocyte handling device and method
US6793387B1 (en) 1999-05-08 2004-09-21 Chata Biosystems, Inc. Apparatus for automatic preparation of a mixture and method
FR2793495B1 (fr) 1999-05-14 2001-08-10 Imv Technologies Dilueur pour la cryoconservation de spermatozoides de bovins
FR2793708B1 (fr) 1999-05-21 2001-08-03 Valois Sa Dispositif de distribution de produit fluide
US6372506B1 (en) 1999-07-02 2002-04-16 Becton, Dickinson And Company Apparatus and method for verifying drop delay in a flow cytometer
IT1307787B1 (it) 1999-07-26 2001-11-19 Univ Firenze Processo per incrementare la motilita' degli spermatozoi e spermatozoia motilita' superiore cosi' ottenuti.
DE19935766A1 (de) * 1999-07-29 2001-02-01 Friedrich Schiller Uni Jena Bu Verfahren zur optischen Anregung von Fluorophor-markierter DNA und RNA
US6664550B2 (en) 1999-08-30 2003-12-16 Sandia National Laboratories Apparatus to collect, classify, concentrate, and characterize gas-borne particles
US6495366B1 (en) 1999-09-03 2002-12-17 Therakos, Inc. Uninterrupted flow pump apparatus and method
WO2001029538A1 (en) 1999-10-20 2001-04-26 Becton Dickinson And Company An apparatus and method employing incoherent light emitting semiconductor devices as particle detection light sources in a flow cytometer
US6813017B1 (en) 1999-10-20 2004-11-02 Becton, Dickinson And Company Apparatus and method employing incoherent light emitting semiconductor devices as particle detection light sources in a flow cytometer
JP2003512605A (ja) 1999-10-21 2003-04-02 サイトメーション， インコーポレイテッド 一時的動的フローサイトメータ分析システム
US6472153B1 (en) 1999-10-26 2002-10-29 Epoch Biosciences, Inc. Hybridization-triggered fluorescent detection of nucleic acids
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
EP1234026B1 (de) 1999-11-30 2011-08-17 Cyntellect, Inc. Verfahren und vorrichtung zur selektiven zielgerichtetheit von spezifischen zellen innerhalb einer zellpopulation
US6263745B1 (en) 1999-12-03 2001-07-24 Xy, Inc. Flow cytometer nozzle and flow cytometer sample handling methods
US6558911B1 (en) 1999-12-10 2003-05-06 Oregon Health Sciences University Sperm quality assay
WO2001049205A1 (es) 2000-01-03 2001-07-12 Iberica De Reproduccion Asistida, S.L. Dispositivo de inseminacion artificial en ganado porcino
US6465169B2 (en) 2000-01-14 2002-10-15 Artemis Pharmaceuticals Gmbh Method for cryoconservation of Zebrafish sperm
EP1118268B1 (de) 2000-01-14 2002-04-17 ARTEMIS Pharmaceuticals GmbH Verfahren zur Kryokonservierung von Zebrafisch-Samen
IT1317724B1 (it) 2000-01-14 2003-07-15 Istituto Sperimentale Italiano Procedimento per la produzione di embrioni non umani di sessopredeterminato ad alto valore genetico.
CA2398107C (en) 2000-01-28 2013-11-19 Althea Technologies, Inc. Methods for analysis of gene expression
US6587203B2 (en) 2000-02-17 2003-07-01 Cornell Research Foundation, Inc. Sort stream stabilizer for flow cytometer
US6618143B2 (en) 2000-02-18 2003-09-09 Idexx Laboratories, Inc. High numerical aperture flow cytometer and method of using same
US6646742B1 (en) 2000-02-19 2003-11-11 Mwi, Inc. Optical device and method for multi-angle laser light scatter
JP3587755B2 (ja) 2000-03-14 2004-11-10 シスメックス株式会社 粒子測定装置およびその方法
GB2360360B (en) 2000-03-14 2002-03-20 Univ Bristol A method of sorting cells
US6482652B2 (en) 2000-03-23 2002-11-19 The Board Of Trustees Of The Leland Stanford Junior University Biological particle sorter
EP1276905A2 (de) 2000-03-30 2003-01-22 Iowa State University Research Foundation Genetische marker für verbesserte fleisch-merkmale in tieren
AU5028701A (en) 2000-04-11 2001-10-23 Chemometec As Method and apparatus for detecting fluorescence of a sample
EP1147774A1 (de) 2000-04-20 2001-10-24 Stichting Dienst Landbouwkundig Onderzoek Verfahren zur Verbesserung der Qualität von Sperma für künstlische Besamung von Tieren
PL359598A1 (en) * 2000-05-09 2004-08-23 Xy, Inc. High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
AU2001274864A1 (en) 2000-05-19 2001-12-03 Cytomation, Inc. A rapid multi-material sample input system
US6784981B1 (en) * 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
US6700130B2 (en) 2001-06-29 2004-03-02 Honeywell International Inc. Optical detection system for flow cytometry
US6590911B1 (en) 2000-06-02 2003-07-08 Coherent, Inc. Passively modelocked harmonic-generating laser
US7351376B1 (en) 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
US6503698B1 (en) 2000-06-16 2003-01-07 The United States Of America As Represented By The Secretary Of Agriculture Cryopreservation of swine embryos
NZ523569A (en) 2000-06-12 2005-11-25 Colorado State University Thro Integrated herd management system utilizing isolated populations of X-chromosome bearing and Y-chromosome bearing spermatozoa
DE10031028B4 (de) 2000-06-26 2008-09-04 Gnothis Holding Sa Verfahren zur Selektion von Partikeln
GB0016920D0 (en) 2000-07-10 2000-08-30 Univ Cambridge Tech Decondensation of DNA
US20040005582A1 (en) * 2000-08-10 2004-01-08 Nanobiodynamics, Incorporated Biospecific desorption microflow systems and methods for studying biospecific interactions and their modulators
NZ523911A (en) 2000-08-10 2005-03-24 Gtc Biotherapeutics Inc Cryopreservation of sperm
FR2813283B1 (fr) 2000-08-25 2003-02-14 Valois Sa Distributeur a pompe integree
EP1190684A1 (de) 2000-09-05 2002-03-27 Universiteit Gent Vorrichtung und Verfahren für die künstliche Besamung von Rindvieh und anderen Tieren
US20020028434A1 (en) 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
AU8898001A (en) 2000-09-08 2002-03-22 Univ Iowa State Res Found Inc Novel prkag3 alleles and use of the same as genetic markers for reproductive andmeat quality traits
EP1334347A1 (de) 2000-09-15 2003-08-13 California Institute Of Technology Miniaturisierte querstromvorrichtungen und -verfahren
GB0023041D0 (en) 2000-09-20 2000-11-01 Univ Manchester Identification apparatus
CN1325909C (zh) 2000-09-27 2007-07-11 清华大学 用于微粒操纵与微粒导向的装置及其使用方法
US7208120B2 (en) 2000-09-27 2007-04-24 The Trustees Of Boston University Cellular diagnostic arrays, methods of using and processing for producing same
BR0005045A (pt) 2000-09-28 2002-05-14 Marcos Fernando De Resende Mat Método para sexagem de espermatozóides usando a via clássica do sistema complemento, com eliminação da via alternativa pela inativação da proteina "b"
US7258774B2 (en) 2000-10-03 2007-08-21 California Institute Of Technology Microfluidic devices and methods of use
AU3651701A (en) 2000-10-05 2002-04-15 Xy Inc System of hysteroscopic insemination of mares
US20040031071A1 (en) * 2000-10-05 2004-02-12 Xy, Inc. System of hysteroscopic insemination of mares
AU2002211913A1 (en) 2000-10-12 2002-04-22 Amnis Corporation Multipass cavity for illumination and excitation of moving objects
JP2004537712A (ja) 2000-10-18 2004-12-16 バーチャル・アレイズ・インコーポレーテッド 多重細胞分析システム
CA2426182C (en) 2000-10-23 2007-03-13 Py Patent, Inc. Fluid dispenser having a housing and flexible inner bladder
CA2428326A1 (en) 2000-11-09 2002-05-16 University Of Guelph Mammalian sex selection using genetic modification
SE0004777D0 (sv) 2000-12-22 2000-12-22 Amersham Pharm Biotech Ab Separation of X-and Y-sperm cells
US20050064383A1 (en) 2000-11-22 2005-03-24 Bashkin James K. Methods and apparatus for producing gender enriched sperm
US20020064809A1 (en) 2000-11-29 2002-05-30 Mutz Mitchell W. Focused acoustic ejection cell sorting system and method
US7713687B2 (en) * 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US6849423B2 (en) 2000-11-29 2005-02-01 Picoliter Inc Focused acoustics for detection and sorting of fluid volumes
CA2468774C (en) 2000-11-29 2015-06-30 George E. Seidel System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US20020064808A1 (en) 2000-11-29 2002-05-30 Mutz Mitchell W. Focused acoustic energy for ejecting cells from a fluid
US6596499B2 (en) 2000-11-30 2003-07-22 The Netherlands Cancer Institute Membrane molecule indicator compositions and methods
US6576291B2 (en) 2000-12-08 2003-06-10 Massachusetts Institute Of Technology Preparation of nanocrystallites
JP2004518127A (ja) 2000-12-15 2004-06-17 サイトメーション， インコーポレイテッド 電気伝導性格納システム
US6577387B2 (en) 2000-12-29 2003-06-10 Johnson & Johnson Vision Care, Inc. Inspection of ophthalmic lenses using absorption
CN1231472C (zh) 2001-01-29 2005-12-14 日内瓦大学 嘧啶无环核苷衍生物、其制备方法及其用途
US6673095B2 (en) * 2001-02-12 2004-01-06 Wound Healing Of Oklahoma, Inc. Apparatus and method for delivery of laser light
US7029916B2 (en) 2001-02-21 2006-04-18 Maxcyte, Inc. Apparatus and method for flow electroporation of biological samples
WO2002077011A2 (en) 2001-03-12 2002-10-03 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Oxidation-reduction sensitive green fluorescent protein variants
US6797139B2 (en) 2001-03-19 2004-09-28 Applera Corporation Detection cell for guiding excitation light therein and method for using same
US6706163B2 (en) 2001-03-21 2004-03-16 Michael Seul On-chip analysis of particles and fractionation of particle mixtures using light-controlled electrokinetic assembly of particles near surfaces
CA2442019A1 (en) 2001-03-22 2002-10-03 Infigen, Inc. Sex-specific selection of sperm from transgenic animals
EP1565747B1 (de) 2001-03-29 2013-11-27 Cellect Technologies Corp. Verfahren and System zum Sortieren und Trennen von Teilchen
DE60218074T2 (de) 2001-03-29 2008-02-07 Sysmex Corp. Durchflusszytometer
US20020159920A1 (en) 2001-04-03 2002-10-31 Weigl Bernhard H. Multiple redundant microfluidic structures cross reference to related applications
JP2002311027A (ja) 2001-04-09 2002-10-23 Hitachi Software Eng Co Ltd ビーズ、ビーズ製造方法、フローサイトメータ及びプログラム
US6416190B1 (en) 2001-04-27 2002-07-09 University Of Chicago Apparatus for using optical tweezers to manipulate materials
US20020186375A1 (en) 2001-05-01 2002-12-12 Asbury Charles L. Device and methods for detecting samples in a flow cytometer independent of variations in fluorescence polarization
WO2002092161A1 (en) 2001-05-10 2002-11-21 Biophan, Llc Miniaturized particle analyzer
US7345758B2 (en) 2001-05-17 2008-03-18 Cytopeia Apparatus for analyzing and sorting biological particles
WO2002092247A1 (en) 2001-05-17 2002-11-21 Cytomation, Inc. Flow cytometer with active automated optical alignment system
US20020182590A1 (en) 2001-05-25 2002-12-05 Vanderbilt University Determining protein function in cell culture using RNA interference
US20030048433A1 (en) 2001-06-01 2003-03-13 Jean-Marie Desjonqueres Cytometer signal processing system and method
FR2825987B1 (fr) 2001-06-19 2003-12-12 Valois Sa Distributeur de produit fluide
US7105355B2 (en) 2001-07-18 2006-09-12 The Regents Of The University Of Michigan Flow cytometers and detection system of lesser size
US7704728B2 (en) 2001-07-18 2010-04-27 The University Of Michigan Microfluidic gravity pump with constant flow rate
FR2828281B1 (fr) 2001-08-02 2004-12-31 Biocytex Dispositif pour l'analyse d'un echantillon notamment par cytometrie de flux
WO2003020877A2 (en) 2001-09-01 2003-03-13 Pharmacia Corporation Staining and sorting genomes and chromosomes using sequence-specific polyamides
DE10151216A1 (de) 2001-10-16 2003-04-24 Zeiss Carl Jena Gmbh Verfahren zur optischen Erfassung von charakteristischen Größen einer beleuchteten Probe
US20030078703A1 (en) 2001-10-19 2003-04-24 Surromed, Inc. Cytometry analysis system and method using database-driven network of cytometers
US6838289B2 (en) 2001-11-14 2005-01-04 Beckman Coulter, Inc. Analyte detection system
US6831279B2 (en) 2001-11-27 2004-12-14 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Laser diode-excited biological particle detection system
WO2003056330A2 (de) 2001-12-31 2003-07-10 Institut für Physikalische Hochtechnologie e.V. Zellsortiersystem zur grössenabhängigen sortierung oder separation von in einer strömenden flüssigkeit suspendierten zellen
AU2002361220A1 (en) 2001-12-31 2003-07-15 Institut Fur Physikalische Hochtechnologie E.V. Micro-recess array for size-dependent sorting or separation of cells suspended in a flowing medium and method for analysing the functional activity of individual cells
EP1468266A4 (de) 2002-01-22 2009-03-11 Beckman Coulter Inc Umweltabgeschlossenes system für ein durchflusszytometer
US6698627B2 (en) 2002-02-19 2004-03-02 Valois S.A.S. Fluid dispenser
US6849394B2 (en) 2002-02-21 2005-02-01 Minitube Of America Compositions comprising reproductive cell media and methods for using such compositions
EP1478739A1 (de) 2002-02-27 2004-11-24 The Regents of the University of Michigan Verfahren und vorrichtung zur sortierung beweglicher teilchen von weniger beweglichen teilchen
US20030175980A1 (en) 2002-03-14 2003-09-18 Hayenga Jon W. Ribbon flow cytometry and cell sorting
US7223371B2 (en) 2002-03-14 2007-05-29 Micronics, Inc. Microfluidic channel network device
JP2004000144A (ja) 2002-03-29 2004-01-08 Aisin Seiki Co Ltd 細胞分離選別装置、細胞整列用基板
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
US20050251476A1 (en) 2002-06-28 2005-11-10 Monsanto Technology Llc Swine genetics business system
US20050222225A1 (en) 2002-07-10 2005-10-06 Applied Research Systems Ars Holding Nv Use of compounds for increasing spermatozoa motility
US20060067916A1 (en) 2002-07-22 2006-03-30 Xy, Inc. Sperm cell process system
MXPA05001100A (es) 2002-08-01 2005-04-28 Xy Inc Sistema de separacion de baja presion para celulas de esperma.
AU2003265471B2 (en) 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) * 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US7201875B2 (en) 2002-09-27 2007-04-10 Becton Dickinson And Company Fixed mounted sorting cuvette with user replaceable nozzle
US20040061853A1 (en) 2002-09-27 2004-04-01 Blasenheim Barry J. Prism-based flow cytometry excitation optics
US6941005B2 (en) 2002-11-01 2005-09-06 Coulter International Corp. Monitoring and control of droplet sorting
WO2004046712A2 (en) 2002-11-20 2004-06-03 University Of Virginia Patent Foundation Isolation of sperm cells from other biological materials using microfabricated devices and related methods thereof
WO2004059282A2 (en) 2002-12-19 2004-07-15 Monsanto Technology Llc Method and means for early detection of pregnancy in animals by combination testing
CA2519989A1 (en) * 2003-03-28 2004-10-14 Monsanto Technology Llc Process for the staining of sperm
JP4614947B2 (ja) 2003-03-28 2011-01-19 イングラン・リミテッド・ライアビリティ・カンパニー 粒子を仕分けるためおよび性別で仕分けられた動物の精子を提供するための装置、および方法
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
US20050011582A1 (en) 2003-06-06 2005-01-20 Haug Jeffrey S. Fluid delivery system for a flow cytometer
US7460223B2 (en) * 2003-09-19 2008-12-02 Applied Biosystems Inc. Inverted orientation for a microplate
PL2151243T3 (pl) 2004-03-29 2013-03-29 Inguran Llc Zawiesiny plemników do sortowania na populacje wzbogacone w niosące chromosom X lub Y
NZ550197A (en) 2004-03-29 2009-10-30 Inguran Llc Use of a composition which regulates oxidation/reduction reactions intracellularly and/or extracellularly in a staining or sorting process of spermatozoa
AU2005266930B2 (en) 2004-07-22 2010-09-16 Inguran, Llc Process for enriching a population of sperm cells
PT1771729E (pt) 2004-07-27 2015-12-31 Beckman Coulter Inc Acentuação da discriminação da citometria de fluxo com transformação geométrica
US20060118167A1 (en) 2004-12-03 2006-06-08 Xy, Inc. Pressure regulated continuously variable volume container for fluid delivery
US20060147894A1 (en) 2004-12-30 2006-07-06 Vicam, L.P. Jacketed vessel for holding semen for sex biasing mammals through artificial insemination and systems and methods for enhancing the probability of sex biasing using the same
US7618770B2 (en) 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US7732408B2 (en) * 2005-10-19 2010-06-08 Iversync Ii Llc Reproductive management
DE202006018701U1 (de) 2006-12-05 2007-03-01 Takata-Petri Ag Gehäuse für eine Gassackanordnung
CN100998524A (zh) 2007-01-19 2007-07-18 北京锦绣大地农业股份有限公司 牛性控胚胎生产方法
NZ590166A (en) 2008-06-30 2013-09-27 Microbix Biosystems Inc Method and apparatus for sorting cells
DE102013226771A1 (de) 2013-12-19 2015-06-25 Robert Bosch Gmbh Verfahren und Vorrichtung zur Masseentkopplung für ein Kraftfahrzeug

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US20150204772A1 (en) 2015-07-23
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US20100007880A1 (en) 2010-01-14
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US7221453B2 (en) 2007-05-22
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EP2264428B1 (de) 2017-05-03
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