US20010016750A1 - Clamp assembly and method of use - Google Patents
Clamp assembly and method of use Download PDFInfo
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- US20010016750A1 US20010016750A1 US09/225,258 US22525899A US2001016750A1 US 20010016750 A1 US20010016750 A1 US 20010016750A1 US 22525899 A US22525899 A US 22525899A US 2001016750 A1 US2001016750 A1 US 2001016750A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
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- A—HUMAN NECESSITIES
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- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12009—Implements for ligaturing other than by clamps or clips, e.g. using a loop with a slip knot
- A61B17/12013—Implements for ligaturing other than by clamps or clips, e.g. using a loop with a slip knot for use in minimally invasive surgery, e.g. endoscopic surgery
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- A61B17/122—Clamps or clips, e.g. for the umbilical cord
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- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
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- A61B17/128—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips
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- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
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- A61B2017/3445—Cannulas used as instrument channel for multiple instruments
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1425—Needle
- A61B2018/1432—Needle curved
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3355—Controlling downstream pump pressure
Abstract
A clamp for clamping a body structure in a patient. The clamp includes a flexible cable housed within a sheath. The cable and sheath extend between a clamp and a handle. The cable actuator. The cable extends through a sheath which is anchored at the clamp and the actuator for actuating jaws from a proximal end of the clamp. A malleable positioner is provided for positioning the clamp about the body structure.
Description
- This application is a continuation of pending U.S. patent application Ser. No. 08/791,130, filed Feb. 13, 1997, which is a continuation of U.S. patent application Ser. No. 08/595,568, filed Feb. 1, 1996, now issued as U.S. Pat. No. 5,626,607, which is a continuation-in-part of 08/567,996, filed Dec. 4, 1995, by inventors Donlon, Stevens, Mueller, Daniel and Gifford, now issued as U.S. Pat. No. 5,618,307, which is a continuation-in-part of application Ser. No. 08/415,273, filed Apr. 3, 1995, by inventors Philip C. Evard et al., now issued as U.S. Pat. No. 5,536,251, and is related to commonly-assigned U.S. patent application No. 08/173,899, filed Dec. 27, 1993, now issued as U.S. Pat. No. 5,425,705, the complete disclosures of which are hereby incorporated by reference.
- This invention relates to less-invasive surgical instruments for clamping hollow body structures. A specific application of the present invention is described in connection with less-invasive devices and methods which can be used for isolating the heart and coronary blood vessels from the remainder of the arterial system. Another specific application of the present invention is for clamping of the internal mammary artery for performing a coronary artery bypass procedure.
- Various cardiovascular, neurosurgical, pulmonary, and other interventional procedures, including coronary artery bypass grafting, heart valve repair and replacement, septal defect repair, pulmonary thrombectomy, removal of atrial myxoma, patent foramen oval closure, treatment of aneurysms, myocardial drilling, electrophysiological mapping and ablation, angioplasty, atherectomy, correction of congenital defects, and other interventional procedures may require general anesthesia, cardiopulmonary bypass, and arrest of cardiac function. In order to arrest cardiac function, the heart and coronary blood vessels must be isolated from the remainder of the circulatory system. This serves several purposes. First, such isolation facilitates infusion of cardioplegic fluid into the coronary arteries to perfuse the myocardium and paralyze the heart without allowing the cardioplegic fluid to be distributed elsewhere in the patient's circulatory system. Second, such isolation facilitates use of a cardiopulmonary bypass system to maintain circulation of oxygenated blood throughout the circulatory system while the heart is stopped without allowing such blood to reach the coronary arteries and resuscitate the heart. Third, in cardiac procedures, such isolation creates a working space into which the flow of blood and other fluids can be controlled or prevented so as to create an optimum surgical environment.
- Circulatory isolation of the heart and coronary blood vessels is usually accomplished by placing a mechanical cross-clamp externally on the ascending aorta downstream of the ostia of the coronary arteries, but upstream of the brachiocephalic artery so that oxygenated blood from the cardiopulmonary bypass system reaches the arms, neck, head, and remainder of the body. Using conventional techniques, the sternum is cut longitudinally (a median sternotomy) thereby providing access between opposing halves of the anterior portion of the rib cage to the heart and other thoracic vessels and organs. Alternatively, a lateral thoracotomy is formed, wherein a large incision is made between two ribs and the ribs are retracted apart. A portion of one or more ribs may be permanently removed to optimize access.
- Through this large opening in the chest, a cross-clamp is placed externally on the ascending aorta thereby isolating the heart and coronary arteries from the remainder of the arterial system. Frequently, the aorta must be dissected away from adjacent tissue to facilitate placement of such a cross-clamp.
- To arrest cardiac function, a catheter is introduced through the sternotomy or thoracotomy and inserted through a puncture in the aortic wall into the ascending aorta between the cross-clamp and the aortic valve. Cardioplegic fluid is infused through the catheter into the aortic root and coronary arteries to perfuse the myocardium. An additional catheter may be introduced into the coronary sinus for retrograde perfusion of the myocardium with cardioplegic fluid. In addition, the myocardium is sometimes cooled by irrigation with cold saline solution and/or application of ice or cold packs to the outside of the heart. Cardiac contractions will then cease.
- In surgical procedures requiring a median sternotomy or other form of gross thoracotomy, the ascending aorta is accessible for placement of an external cross-clamp through the large opening in the chest. However, such open-chest surgery often entails weeks of hospitalization and months of recuperation time as well as pain and trauma suffered by the patient. Moreover, the average mortality rate associated with this type of procedure is about two to fifteen percent for first-time surgery, and mortality and morbidity are significantly increased for reoperation.
- New devices and methods are therefore desired to facilitate the performance of cardiac procedures such as heart valve repair and replacement, coronary artery bypass grafting, and the like, using minimally invasive techniques, eliminating the need for a gross thoracotomy. Such techniques are described in U.S. Pat. No. 5,452,733, and application Ser. No. 08/163,241 filed Dec. 6, 1993, which are assigned to the assignee of the present invention and are incorporated herein by reference. In those applications, methods and devices are described for performing coronary artery bypass grafting, heart valve repair and replacement, and other procedures through small incisions or cannulae positioned in the chest wall, obviating the need for a gross thoracotomy. One technique described for arresting the heart during such procedures involves the use of a catheter which is introduced into a peripheral artery such as a femoral artery and positioned in the ascending aorta. An expandable member at the distal end of the catheter is expanded within the ascending aorta to block blood flow therethrough. Cardioplegic fluid is then be infused into the aortic root and into the coronary arteries through a lumen in the catheter, and/or in a retrograde manner through a catheter positioned in the coronary sinus, paralyzing the myocardium.
- While this endovascular technique for arresting the heart provides significant advantages over conventional open-chest techniques, in some circumstances the use of an endovascular device for aortic partitioning may be undesirable. For example, in some cases the patient's femoral arteries and other vessels in which such a device could be introduced may not be suitable for such introduction, due to inadequate vessel diameter, vessel stenosis, vascular injury, or other conditions. In addition, where a number of endovascular cannulae are to be introduced to support cardiopulmonary bypass, retroperfusion of cardioplegic fluid, removal of blood from the heart, and other functions, a suitable arterial location for introduction of an endovascular aortic partitioning device may not be available. Further, it may be desirable to minimize the number of arterial punctures so as to reduce the risk of infection and other complications stemming from such punctures.
- The present invention also provides an improved method and apparatus for clamping a patient's internal mammary artery for performing a coronary artery bypass procedure. In order to use a mammary arterial graft in a coronary artery bypass procedure, blood flow through the target mammary artery is temporarily stopped using a removable surgical clamp. In a conventional open-chest procedure, a relatively large, easy to handle clamp is applied by hand or with a forceps directly to the mammary artery through the large opening in the patient's chest provided by a median sternotomy. After the mammary artery is clamped, the mammary artery is ligated and divided at a location downstream from the clamp to create a free end which is connected to the coronary artery. After the grafting is complete, the clamp is removed by the surgeon, typically by hand or with the open forceps, to permit blood to flow through the mammary artery and into the coronary artery downstream of the blockage. As discussed above, gross thoracotomies used in conventional open heart surgery are highly traumatic to the patient and, therefore, new methods of performing surgery on the heart using minimally-invasive techniques have been recently developed. A further application of the present invention is for clamping the internal mammary artery for performing a coronary artery bypass procedure when performing minimally invasive heart surgery.
- The present invention provides less-invasive devices and methods for clamping a body structure. An application of the present invention is described in connection with temporarily clamping a patient's internal mammary artery for performing a coronary artery bypass. Although the present invention is described in connection with clamping of the internal mammary artery, it is understood that the methods and apparatus described herein may be used to clamp any other body structure in a patient.
- In a preferred embodiment of the invention, the clamp assembly includes a clamp, a handle, and a cable housed within a sheath extending between the clamp and the handle. The handle includes a cable puller and a first sheath holder. A proximal end of a cable is connected to the cable puller and a proximal end of the sheath is held by the first sheath holder. The clamp is coupled to the distal end of the cable and sheath. The clamp includes a first jaw which is movable between an open position and a closed position relative to a second jaw. In a preferred embodiment, the second jaw is also movable between the open and closed positions. The first and second jaws preferably move parallel to one another so that shear forces are not applied to the body structure thereby minimizing trauma to the body structure. Parallel jaws also offer a uniform force distribution over the length of the jaws. The first and second jaws may, of course, also move in any other manner relative to one another. The cable puller is preferably slidably mounted to the handle. The cable puller may also be coupled to the handle in any other manner. For example, the cable puller may be rotatably coupled to the handle.
- An actuator is coupled to the cable puller for actuating the first jaw. A spring is mounted to the handle or clamp for providing a biasing force between the cable and the sheath. The spring preferably has a side which contacts the actuator for biasing the actuator. The actuator is preferably threadably coupled to the cable puller so that rotation of the actuator changes the compression of the spring thereby changing the clamping force exerted by the first and second jaws. The spring is preferably mounted so that the cable and cable puller extend through the spring.
- The clamp assembly of the present invention provides a clamp which can be actuated from a location remote from the clamp and is therefore suitable for minimally invasive surgical techniques such as the coronary artery bypass procedure described above. An advantage of the clamp of the present invention is that the cable and sheath are flexible so that the clamp can be positioned in a convenient location which does not hinder access or use of other instruments. Another advantage of the present invention is that the flexible cable and sheath can be positioned through an instrument delivery member, such as a trocar, cannula, or retractor, while permitting other instruments to pass through the same instrument delivery member with minimal interference. In this manner, the number of openings in the patient is minimized.
- The clamp assembly of the present invention also preferably includes an introducer which is releasably attached to the clamp. The introducer is more rigid than the cable and sheath so that the introducer may be used to position the clamp around the desired body structure. The introducer is preferably releasably coupled to the handle but may also be completely independent of the handle. The introducer is preferably malleable so that it can be deformed into a desired shape for positioning the clamp around other body structures in the patient if a curved path to the clamped body structure is required.
- Because the patient's chest is preferably closed during the procedure except for one or more small percutaneous intercostal penetrations, visualization within the thoracic cavity is usually required to facilitate accurate positioning of the clamp and/or the delivery cannula. In an exemplary embodiment, a viewing device such as an endoscope or thoracoscope is positioned in a percutaneous intercostal penetration in the patient's chest to facilitate viewing at least a portion of the thoracic cavity. Other viewing devices may also be used which use ultrasound, transesophageal echocardiography, fluoroscopy, and the like. Although it is preferred to use an indirect visualization device, a small incision may be provided between adjacent ribs for direct visualization.
- The terms “percutaneous intercostal penetration” and “intercostal penetration” as used herein refer to a penetration, in the form or a small cut, incision, hole, cannula, trocar sleeve, or the like through the chest wall between two adjacent ribs, wherein the patient's rib cage and sternum remain substantially intact, without cutting, removing, or significantly displacing the ribs or sternum. These terms are intended to distinguish between a gross thoracotomy, wherein the sternum and/or one or more ribs are cut or removed from the rib cage, or one or more ribs are retracted significantly, to create a large opening into the thoracic cavity. A “percutaneous intercostal penetration” may abut or overlap the adjacent ribs between which it is formed, but the maximum width of the penetration which is available for introduction of instruments into the thoracic cavity will be the width of the intercostal space, bounded by two adjacent ribs in their natural, substantially undeflected positions. It should be understood that one or more ribs may be retracted or deflected a small amount and/or a small amount of intercostal cartilage may be removed without departing from the scope of the invention, however, it is an objective of the invention to avoid the pain, trauma, and complications which result from large incisions and/or significant deflection or cutting of ribs in conventional, open-chest techniques.
- A further understanding of the nature and advantages of the invention may be realized by reference to the remaining portions of the specification and drawings. It should be understood that while the invention is described in the context of thoracoscopic surgery on the mammary and coronary arteries, the system and method disclosed herein are equally useful on other types of body structures in the abdomen, pelvis, thorax and other body cavities.
- FIG. 1 is a perspective view of a first embodiment of a thoracoscopic aortic clamping device.
- FIG. 2A is a side cross-sectional view of the aortic clamping device of FIG. 1.
- FIG. 2B is a distal end view of the aortic clamping device of FIG. 1.
- FIG. 3 is a perspective view of a second embodiment of a thoracoscopic aortic clamping device.
- FIG. 4A is a side cross-sectional view of a proximal portion of the aortic clamping device of FIG. 3.
- FIG. 4B is a side cross-sectional view of a distal portion of the aortic clamping device of FIG. 3.
- FIG. 4C is a distal end view of the aortic clamping device of FIG. 3.
- FIG. 5A is a side cross-sectional view of a further embodiment of a thoracoscopic aortic clamping device showing a proximal portion thereof.
- FIG. 5B is a side cross-sectional view of a distal portion of the aortic clamping device of FIG. 5A.
- FIG. 5C is a distal end view of the aortic clamping device of FIG. 5A.
- FIG. 5D is a front view of a staple for closing an aortic puncture in the aortic clamping device of FIG. 5A.
- FIG. 5E is a top view of the staple of FIG. 5D.
- FIGS.6A-6D are side cross-sectional views of a distal portion of the aortic clamping device of FIGS. 5A-5D showing the delivery cannula penetrating the aortic wall and a staple closing a puncture in the aortic wall.
- FIG. 7 is a side partial cross-sectional view of a further embodiment of a thoracoscopic aortic clamping device and delivery cannula.
- FIG. 8 is a side view of a distal portion of the aortic clamping device of FIG. 7.
- FIG. 9 is a side cross-sectional view of the delivery cannula in the aortic clamping device of FIG. 7.
- FIG. 10A is a side cross-sectional view of another embodiment of an aortic clamping device and delivery cannula.
- FIG. 10B is a top view of a distal portion of the aortic clamping device of FIG. 10A in a unclamped position.
- FIG. 11 is a top view of a distal portion of the aortic clamping device of FIG. 10A in a clamped position.
- FIGS.12A-12B are side views showing the aortic clamping device of FIG. 10A positioned in the patient's ascending aorta in an open position and a clamped position, respectively.
- FIGS. 13 and 14 are side views illustrating alternative embodiments of the aortic clamping device of FIG. 10A positioned in the patient's ascending aorta.
- FIG. 15 is a front view of a patient showing the positioning of the delivery cannula and cardiopulmonary bypass cannulae in the patient's circulatory system to facilitate arresting cardiac function.
- FIG. 16 is a front view of the interior of a patient's thoracic cavity illustrating the positioning of the aortic clamping device of FIG. 3 about the patient's ascending aorta.
- FIG. 17 is an external view showing a clamp assembly having a clamp and a clamp positioner.
- FIG. 18 is an exploded isometric view of the clamp of FIG. 17.
- FIG. 19 is an enlarged external view of the proximal end of the clamp of FIG. 17.
- FIG. 20 is an enlarged cross-sectional view of the clamp of FIG. 19 with the jaws in a closed position.
- FIG. 21 is an enlarged cross-sectional view of the clamp of FIG. 19 with the jaws in an open position.
- FIG. 22 is an enlarged view of the distal end of the clamp positioner of FIG. 17.
- FIG. 23 is a front view of the interior of a patient's thoracic cavity illustrating the use of trocar sleeves between the patient's ribs to introduce various thoracoscopic surgical devices into the thoracic cavity and a detachable clamp clamping the ascending aorta during a surgical procedure.
- FIG. 24 is an enlarged view of a portion of FIG. 23 illustrating the distal end of an alternative clamp positioner used with the alternative clamp of FIGS. 23 and 24.
- FIG. 25 is a side view of a further clamping assembly in which the jaws are actuated with a drive rod.
- FIG. 26 is an end view of the clamp of FIG. 25 taken along line26-26.
- FIGS.27A-B are enlarged cross-sectional views of the proximal portion of the clamp of FIG. 25 in the closed and opened positions.
- FIGS.28A-C are plan, side and end views of another clamp.
- FIGS.29A-B are side views of a further clamp in closed and opened positions.
- FIG. 30A is a side view of a further clamping assembly showing the clamp in a closed position and the distal end of the clamp positioner adjacent the clamp.
- FIG. 30B illustrates the clamp of FIG. 30A in an open position with portions broken away to show internal detail.
- FIG. 30C is a plan view of the distal end of the clamp positioner of FIG. 30A.
- FIG. 31A is a further clamping assembly in which the clamp positioner includes a coaxial cable to actuate the jaws of the clamp.
- FIG. 31B shows an alternative embodiment of the clamp of FIG. 31A using a torsion spring.
- FIG. 31C shows a further alternative embodiment of the clamp of FIG. 31A in which the jaws move along straight lines relative to one another and a compression spring is used to bias the jaws.
- FIG. 31D illustrates an alternative embodiment of the clamp of FIG. 31C using a scissors mechanism to maintain the straight line movement of the jaws.
- FIG. 31E illustrates another embodiment of the clamp of FIG. 31A using jaws with concave, opposed, atraumatic surfaces and a scissors-like opening and closing action.
- FIG. 31F illustrates a portion of the clamp of FIG. 31D providing a clamping force to a hollow body structure.
- FIG. 32A illustrates a further clamping assembly using hydraulic pressure to actuate the clamp through a piston and cylinder arrangement.
- FIG. 32B illustrates an alternative embodiment of the clamp of FIG. 32A.
- FIG. 33A shows a clamp having jaw surfaces defined by inflatable balloons.
- FIG. 33B illustrates the distal ends of the jaws of FIG. 33 with the inflatable balloons inflated to close the opposed surfaces between the jaws.
- FIG. 34 is a simplified view showing a side biting clamp clamping onto a blood vessel.
- FIG. 35 shows a clamp assembly with the proximal end having a handle in cross-section and the distal end having a clamp in partial cross-section.
- FIG. 36 shows an introducer for introducing the clamp of FIG. 35 into a patient.
- FIG. 37 shows the clamp assembly of FIG. 35 with the clamp having a high clamping force.
- FIG. 38 shows the jaws of the clamp partially open.
- FIG. 39 shows the jaws in the fully open position.
- FIG. 40 is a side view of a first jaw.
- FIG. 41 is a side view of a second jaw with a jaw member attached.
- FIG. 42 is a plan view of the first and second jaws.
- FIG. 43 is a side view of the jaw member.
- FIG. 44 is an enlarged cross-section of the clamp of FIG. 39 along line A-A of FIG. 39.
- FIG. 45 is a side view of a slide.
- FIG. 46 is a plan view of the slide.
- FIG. 47 is a side view of an anchor.
- FIG. 48 is a plan view of the anchor.
- FIG. 49 shows the malleable introducer mounted to the clamp and the handle.
- FIG. 50 is a plan view of an alternative handle for the clamp assembly of FIGS.35-49 with a spring force indicator.
- FIG. 51 is a partial cross-sectional view of the handle of FIG. 50.
- A first preferred embodiment of a thoracoscopic aortic clamping device according to the invention is illustrated in FIGS. 1, 2A, and2B.
Device 20 includes a tubularouter shaft 22 having aproximal end 24 and adistal end 26.Outer shaft 22 preferably has a length of about 10 to 35 cm so thatdistal end 26 may reach the ascending aorta from a lateral side or an anterior side of the chest. Adrive shaft 28 extends throughouter shaft 22 and is axially rotatable therein. A fixedjaw 30 is mounted todistal end 26 ofouter shaft 22. Amovable jaw 32 is mounted todistal end 33 ofdrive shaft 28 in opposition tojaw 30 so as to facilitate clamping the aorta therebetween.Jaws contact surface 34 configured to engage the exterior of the aorta, which may include textural features to enhance grip on the aorta. An elastomeric pad or cover (not shown) of silicone or other low durometer material may further be provided over contact surfaces 34 to reduce trauma on aortic tissue. - An actuator36 is mounted at
proximal end 24 ofouter shaft 22. Actuator 36 includes ahandle 38 mounted toproximal end 24 ofouter shaft 22, and amovable handle 40 mounted to driveshaft 28. By pivotinghandle 40 relative to handle 38,drive shaft 28 rotates withinouter shaft 22, thereby opening and closingjaws extensions 42 onhandles -
Device 20 further includes adelivery cannula 44 for delivering cardioplegic fluid into the aorta whilejaws Delivery cannula 44 has aproximal end 46 and adistal end 48 to which aneedle 50 is attached.Needle 50 is dimensioned and configured to penetrate the ascending aortic wall into the aortic lumen, preferably having a length of about 1 cm to 3 cm. Adelivery lumen 52 extends throughcannula 44 and is in fluid communication with a port 54 near the distal end ofneedle 50. A luer fitting 56 is mounted toproximal end 46 ofcannula 44, and is configured to engage a complementary luer fitting 58 mounted to the proximal end ofdrive shaft 28. Luer fitting 56 includes abarb 60 for connecting a hose (not shown) for delivering cardioplegic fluid intodelivery lumen 52. Usually, the hose will be connected to a cardioplegic fluid pump designed to deliver a continual or periodic flow of cardioplegic fluid into the aorta during a procedure. - It may be seen that
jaws outer shaft 22 and driveshaft 28 so as to permit introduction ofneedle 50 into the aorta upstream from the point at whichjaws -
Needle 50 is usually in the range of 10 gauge to 16 gauge so as to facilitate infusion of cardioplegic fluid into the aorta at a rate sufficient to paralyze the myocardium and to maintain such paralysis. Preferably, the size ofneedle 50 is minimized so that the puncture made in the ascending aorta will not bleed excessively whenneedle 50 is withdrawn from the aortic wall. However, in some cases, the puncture will require closure by means of sutures, staples, or other means, as described more fully below. To avoid the need for such closure, a plurality of smaller needles may be mounted todistal end 48 ofdelivery cannula 44 as an alternative to a singlelarger needle 50. The number and size of the needles are selected to provide an adequate total flow rate of cardioplegic fluid into the aorta, yet each needle is sufficiently small, e.g. less than about 0.025 in. outer diameter, so that each puncture need not be closed after withdrawal of the needles from the aortic wall due to normal blood clotting. - A second preferred embodiment of a thoracoscopic aortic clamping device according to the invention is illustrated in FIGS. 3 and 4A-4C. In this embodiment,
device 64 includes a tubularouter shaft 66 having aproximal end 68 and adistal end 70. A tubularinner shaft 72 is slidably disposed withinouter shaft 66 and has aproximal end 74 and adistal end 76. A pair ofjaw extensions inner shaft 72, each having an outwardly angleddistal portion jaws core tube 86 is disposed betweenjaw extensions inner shaft 72, and aninner lumen 88 extends throughcore tube 86. Delivery cannula 44 (described above) may be inserted throughinner lumen 88 so thatneedle 50 extends distally from thedistal end 76 ofinner shaft 72. As best illustrated in FIG. 4C,jaws outer shaft 70 andinner shaft 76 so as to permit introduction ofneedle 50 into the aorta upstream from the point at whichjaws Jaws elastomeric pads - A
handle 90 is attached to theproximal end 68 ofouter shaft 66 and includes ahousing 92 to which is coupled alever 94. Apin 96 extends through adistal end 98 oflever 94, and is slidable within a pair ofslots 100 inhousing 92. Alink 102 is pivotally coupled at one end to lever 94 in a middle portion thereof, and at the other end tohousing 92 proximal toslots 100.Inner shaft 72 is attached at itsproximal end 74 todistal end 98 oflever 94. In this way, pivotinglever 94 towardhousing 92 translates the lever distally withinslots 100, thus translatinginner shaft 72 distally overjaw extensions Distal end 76 ofinner shaft 72 engages angleddistal portions jaw extensions jaws housing 92 andlever 94 to biaslever 94 againsthousing 92 to maintainjaws -
Core tube 86 is fixed tohousing 92 at aproximal end 104 thereof. A luer fitting 106 is mounted to the exterior ofhousing 92 and has an interior passage in communication withinner lumen 88. Whenjaws delivery cannula 44 may be inserted throughinner lumen 88 untilneedle 50 penetrates the aortic wall upstream ofjaws delivery cannula 44 may be locked onto luer fitting 106 onhousing 92. A hose may be connected tobarb 60 ondelivery cannula 44 to deliver cardioplegic fluid into the aorta throughdelivery lumen 52. - As described above, the aortic puncture created by
needle 50 may sometimes require closure after withdrawal of the needle to prevent excessive bleeding when cardiac function is restored. Such closure may be performed by means of thoracoscopic instruments, such as staple appliers or suturing instruments. Alternatively, a means for closing the aortic puncture may be integrated into the aortic clamping device of the invention. An example of such a device is illustrated in FIGS. 5A-5D and 6A-6D. In this embodiment, clampingdevice 110 comprises the same jaw configuration, handle, and jaw closure mechanism as the embodiment of FIGS. 3 and 4A-4B.Device 110 further includes aninner sleeve 112 slidably disposed withincore tube 86 and having aproximal end 114, adistal end 116 and alumen 118 therebetween. Adelivery tube 120 resides withinlumen 118 and has a fitting 122 at its distal end to which aneedle 124 is attached. -
Distal end 116 ofinner sleeve 112 is configured to retain astaple 126 withinlumen 118.Staple 126 comprises, as shown in FIGS. 5D-5E, at least twolegs flexible cross member 132.Legs distal points legs member 132 such that points 134, 136 are closer together than the remainder oflegs Legs cross member 132 is deflected into a curved configuration, (shown in phantom in FIG. 5D). Whenlegs legs staple 126 may be applied to the aorta withlegs legs staple 126 may have three, four, or more legs with inwardly disposed distal points. Shallow axial channels (not shown) may be provided on opposing sides oflumen 118 extending proximally fromdistal end 116 in whichlegs staple 126. - As shown in FIG. 5E,
cross member 132 has abore 138 in a middle portion thereof that is larger thanneedle 124, but smaller than fitting 122. The staple is held withinlumen 118 so thatneedle 124 is aligned withbore 138. As shown in FIGS. 6A-6B, by distally advancingsleeve 112 anddelivery tube 120 in tandem,needle 124 penetrates the aortic wall whilestaple 126 is applied to aorta A withlegs Sleeve 112 may then be retracted proximally whiledelivery tube 120 remains in position, wherein fitting 122 holds staple 126 in the aortic wall andlegs delivery tube 120 may be retracted, removingneedle 124 from aorta A and leavingstaple 126 in the aortic wall to close the puncture created by needle 124 (FIG. 6D). - The means for actuating
sleeve 112 anddelivery tube 120 will be described with reference to FIG. 5A. Anactuation button 140 is mounted at the proximal end ofhousing 92 and is biased in an outward position by aspring 142.Actuation button 140 is coupled to anadaptor 144 fixed toproximal end 146 ofdelivery tube 120.Adaptor 144 has an inner chamber (not shown) in communication with the interior ofdelivery tube 120. An arm 148 onadaptor 144 has an inner passage (not shown) in communication with the inner chamber ofadaptor 144 and is configured for connection to a flexible tube 150. Tube 150 connects to a fitting 152 mounted tohousing 92, which may be connected to ahose 154 from a cardioplegic fluid delivery device. - A pawl156 is pivotally mounted to
adaptor 144 and is biased by a spring (not shown) to engage a set of linear teeth 158 onhousing 92, thus providing a ratcheted locking mechanism to maintainactuator button 140 in a depressed position. A catch 160 is pivotally mounted toadaptor 144 and is biased in a counter-clockwise direction. Asactuator button 140 is depressed,delivery tube 120 advances distally relative tosleeve 112 until catch 160 engagesproximal end 114 ofsleeve 112, at whichpoint needle 124 andstaple 126 are in the position shown in FIG. 6A. Further depression ofactuator button 140 advancesdelivery tube 120 andsleeve 112 in tandem, allowingneedle 124 andstaple 126 to penetrate the aortic wall, as shown in FIG. 6B. Delivery of cardioplegic fluid into aorta A may then be initiated throughhose 154, tube 150,delivery tube 120, andneedle 124. When the procedure is complete, cardioplegic fluid delivery is terminated and arelease button 162 is pressed, which pivots catch 160 in a clockwise direction, allowingsleeve 112 to retract proximally under the force of aspring 164 disposed about the proximal end ofsleeve 112. At this point,sleeve 112,delivery tube 120, andstaple 126 are in the positions shown in FIG. 6C.Sleeve 112 retracts relative todelivery tube 120 until itsproximal end 114 engages arelease arm 166 on pawl 156, disengaging pawl 156 from teeth 158 and allowingdelivery cannula 120 andactuator button 140 to retract. In this way, with the press of a single release button,needle 124 is removed from aorta A andstaple 126 is applied to aortic wall to close the puncture created byneedle 124, as illustrated in FIG. 6D.Staple 126 may remain in the patient's body indefinitely, may be resorbable, or may be surgically removed using thoracoscopic instruments after clotting has occurred or the aortic puncture has healed. - A further embodiment of an aortic clamping device according to the invention is illustrated in FIGS.7-9. In this embodiment, clamping
device 170 is constructed in large part like the embodiment of FIGS. 3 and 4A-4C, except that noinner lumen 88 is required for insertion of adelivery cannula 44, and thatjaws shafts endovascular delivery cannula 172 positioned within the aortic lumen betweenjaws delivery cannula 172 comprises aflexible shaft 174 of a biocompatible polymer such as polyurethane, polyvinyl chloride, polyether block amide, or polyethylene, with adistal end 176, aproximal end 178, and at least one inner lumen 180 therebetween. Aport 182 is disposed atdistal end 176 in fluid communication with inner lumen 180, to facilitate infusion of cardioplegic fluid into the aorta. Asoft tip 184 may be provided ondistal end 176 to reduce the risk of injury to vessel walls, to the aortic valve, or to other tissue. Asecond lumen 186 may also be provided with aport 188 neardistal end 176, to facilitate infusion or aspiration of fluids, pressure measurement, and the like. Anadaptor 190 is attached toproximal end 178 and has afirst arm 192 with apassage 193 in communication with inner lumen 180 and asecond arm 194 with apassage 195 in communication withsecond lumen 186.First arm 192 may be connected to a hose from a cardioplegic fluid delivery pump, whilesecond arm 194 may be connected to a pressure measurement device, aspiration device, fluid delivery device, or the like. - As illustrated in FIGS.7-8,
delivery cannula 172 is positioned in the aorta A, withdistal end 176 in the ascending aorta between the brachiocephalic artery and the coronary ostia.Shaft 174 preferably has a length of at least about 80 cm to allow introduction into a femoral artery and transluminal positioning ofdistal end 176 in the ascending aorta.First arm 192 may be connected to acardioplegic fluid supply 196, whilesecond arm 194 may be connected to apressure measurement device 198.Jaws aortic clamping device 170 are positioned about the ascending aorta A between the brachiocephalic artery and the coronary arteries.Jaws lever 94, which extendsinner shaft 66 overangled segments Jaws delivery cannula 172, as shown in FIG. 8. Cardioplegic fluid may then be delivered through inner lumen 180, while the pressure within the aorta upstream of clampingdevice 170 may be measured throughsecond lumen 186. - Referring now to FIGS.10A-10B and 11, a further embodiment of an aortic clamping device according to the invention will be described. In this embodiment,
aortic clamping device 200 comprises ashaft 202 having adistal end 204, aproximal end 206, and first andsecond lumens strap 212 is slidably disposed infirst lumen 208 and extends distally through anopening 214 indistal end 204. Ananchor 216 is attached to the distal end ofcable 212. Awire 218 is slidably disposed insecond lumen 210 and has aloop 220 extending distally fromdistal end 204 ofshaft 202.Loop 220 has a width which narrows in the distal direction, so thatanchor 216 may be passed through a proximal portion ofloop 220, and trapped in a distal portion ofloop 220. - A
handle 222 is attached toproximal end 204 ofshaft 202 and has agrip 224 suitable for grasping with the user's hand. Alever 226 is pivotally mounted to handle 222 and has anupper end 227 to which aspring 228 is attached to biasupper end 227 in a proximal direction.Wire 218 has asecond loop 230 at its proximal end to which is attached aflexible cord 232.Cord 232 extends around apulley 234 rotatably coupled to handle 222 and attaches toupper end 227 oflever 226. Agear 233 is mounted to lever 226 and is engaged by apawl 235 pivotally mounted to handle 222.Cable 212 extends throughhandle 222 and exits through anopening 236, with aproximal end 238 disposed outside ofhandle 222. An anchor ball 240 is attached toproximal end 238 and has a width larger than that of opening 236 to prevent passage therethrough. Anchor ball 240 may be configured to allow adjustment of its longitudinal position oncable 212 to facilitate use ofdevice 200 on aortas of various sizes. - Usually,
aortic clamping device 200 is used in conjunction withdelivery cannula 172, described above in connection with FIGS. 7-9. As shown in FIGS. 12A-12B,delivery cannula 172 is first introduced into the patient's arterial system, usually through a femoral artery, and advanced so thatdistal end 176 is in the ascending aorta A between brachiocephalic artery B and coronary ostia C.Aortic clamping device 200 is positioned so thatdistal end 204 is adjacent the aorta at the point it is to be clamped. As shown in FIGS. 10A-10B,cable 212 is wrapped around aorta A, usually by means of conventional thoracoscopic instruments such as forceps and/or needle drivers, andanchor 216 is inserted throughloop 220.Lever 226 is then actuated, drawinganchor 216 andcable 212 proximally throughlumen 210 so as to tightencable 212 around aorta A until the aortic wall seals against the exterior ofdelivery cannula 172, as shown in FIGS. 11 and 12B. - In an exemplary embodiment, as shown in FIGS.12A-12B,
delivery cannula 172 has apad 242 of silicone or other low durometer polymer fixed to its exterior neardistal end 176 to minimize trauma to the aortic wall and to resist movement of the cannula during clamping. Astiffener coil 244 embedded inshaft 174 may also be provided to maintain the patency oflumens 180, 186 during clamping. In addition,shaft 202 may be bendable to facilitatepositioning shaft 202 through an intercostal space withdistal end 204 near the ascending aorta. - To release
aortic clamping device 200 from aorta A,cable 212 may be severed by inserting a scissors or knife throughside port 246 inhandle 222, thereby releasing tension oncable 212 and allowing thedevice 200 to be withdrawn from the thoracic cavity. Alternatively, anchor ball 240 may be configured to be removable fromproximal end 238 ofcable 212. Or, arelease cord 248 coupled topawl 235 may be provided to facilitate disengagingpawl 235 fromgear 233, allowinglever 226 to return to its outward position, thereby releasing tension oncable 212.Anchor 216 may then be removed fromloop 220 using thoracoscopic instruments, allowingdevice 200 to be removed from the thoracic cavity. - FIGS. 13 and 14 illustrate two alternative constructions of
delivery cannula 172 in conjunction withaortic clamping device 200. In the embodiment of FIG. 13,delivery cannula 172 includes aballoon 250 attached toshaft 174 and spaced proximally from distal end 176 a sufficient distance to allow aorta A to be clamped aboutshaft 174 distal to balloon 250. The interior ofballoon 250 is in communication with an inflation lumen (not shown) inshaft 174 for delivery of an inflation fluid into the balloon, and is configured to fully occlude the aortic lumen when inflated. A plurality ofports 252 are provided inshaft 174 distal to balloon 250 and are in communication with an aspiration lumen (not shown) within shaft 274. In this way, whencable 212 is released after a procedure, any air, fluids, thrombus, and/or other emboli which might have been produced are prevented from flowing downstream byballoon 250, and may be aspirated from the arterial system throughports 252. - In the embodiment of FIG. 14,
delivery cannula 172 includes an aortic occlusion means 254 atdistal end 176 ofshaft 174. Occlusion means 254 is configured to completely occlude the aortic lumen, and may be funnel-shaped with a tapered interior passage in communication with an aspiration lumen (not shown) inshaft 174. In this way, air, fluids, thrombus, and/or other emboli which might be produced during a procedure distal to the point of clamping are trapped in occlusion means 254 and may be withdrawn from the arterial system through the aspiration lumen indelivery catheter 174. Occlusion means 254 is preferably a soft collapsible material to allow it to be collapsed and inserted into a sheath for introduction. The sheath may be positioned in the ascending aorta, then retracted to allow occlusion means 254 to expand and occlude aorta A.Aortic clamping device 200 may then be used to clamp aorta A aboutshaft 174. - The method of the invention will now be described with reference to FIGS. 15 and 16. The patient is first placed on cardiopulmonary bypass, using the system illustrated in FIG. 15. A
venous cannula 260 is positioned in a vein V of the patient, preferably a femoral vein in the groin area, and advanced into the inferior vena cava IVC and/or into the interior of heart H to withdraw deoxygenated blood therefrom.Venous cannula 260 may alternatively be introduced thoracoscopically into the inferior vena cava IVC, into the superior vena cava SVC, or into the right atrium RA.Venous cannula 260 is connected to acardiopulmonary bypass system 262 which receives the withdrawn blood, oxygenates the blood, and returns the oxygenated blood to anarterial return cannula 264 positioned in an artery AR, preferably a femoral artery.Arterial return cannula 264 may alternatively be introduced thoracoscopically directly into an ascending or descending portion of the aorta A. - A
pulmonary venting catheter 266 may also be utilized to withdraw blood from the pulmonary trunk PT.Pulmonary venting catheter 266 may be introduced from the neck through the internal jugular vein JV and superior vena cava SVC, or from the groin through femoral vein V and inferior vena cava IVC. Usually, a Swan-Ganz catheter (not shown) is first introduced and positioned in pulmonary trunk PT using well-known techniques, andpulmonary venting catheter 266 is then introduced over the Swan-Ganz catheter. Blood is withdrawn from pulmonary trunk PT through a port at the distal end ofpulmonary venting catheter 266 and an inner lumen extending through the catheter outside of the patient's body.Pulmonary venting catheter 266 may further have one ormore balloons 268 at its distal end proximal to the distal port for occluding pulmonary trunk PT. - An alternative method of venting blood from pulmonary trunk PT is described in U.S. Pat. No. 4,889,137, which is incorporated herein by reference. In the technique described therein, a catheter is positioned from the internal jugular vein JV in the neck through the right atrium, right ventricle, and pulmonary valve into the pulmonary trunk PT. The catheter has a coil about its periphery which holds the pulmonary valve open so as to drain blood from pulmonary trunk PT, thereby decompressing the left side of the heart.
- For purposes of arresting cardiac function, a
delivery cannula 172 may be positioned in a femoral artery AR by a percutaneous technique such as the Seldinger technique, or through a surgical cut-down CD.Delivery cannula 172 is advanced, usually over a guidewire (not shown), until itsdistal end 176 is disposed in the ascending aorta AA between the coronary ostia C and the brachiocephalic artery B. Blood may be vented from ascending aorta AA through aport 182 at the distal end ofdelivery cannula 172 in communication with inner lumen 180 indelivery cannula 172, through which blood may flow toproximal end 178. The blood may then be directed to a blood filter/recovery system 270 to remove emboli, and then returned to the patient's arterial system viaCPB system 262. - Ascending aorta AA may then be clamped using one of the various embodiments of aortic clamping device described above. FIG. 16 illustrates the use of
aortic clamping device 110 of FIGS. 5A-5D.Shaft 66 of clampingdevice 110 is positioned through the chest wall and into the thoracic cavity TC through an intercostal space I between two adjacent ribs R. Another preferred entry for theshaft 66 is through a penetration on the patient's right hand side between the first and second ribs. A trocar sleeve may be positioned in the chest wall within an intercostal space to facilitate introduction of clampingdevice 110. An endoscope positioned in thoracic cavity TC through and intercostal space I may be used for visualization to facilitate accurate positioning ofclamping device 110.Jaws Lever 94 is then actuated to closejaws - When it is desired to arrest cardiac function, a cardioplegic fluid such as potassium chloride (KCl) is delivered to the myocardium in at least one of several ways. Clamping
device 110 includes an integrated cardioplegic fluid delivery cannula 120 (FIGS. 5A-5D), which may be activated by depressingactuator button 140 onhandle 90.Needle 124 will penetrate the aortic wall upstream ofjaws cardioplegic fluid pump 276 connected to fitting 152 in communication withdelivery cannula 120. - As alternative or addition to delivery by means of clamping
device 110, cardioplegic fluid may be delivered in an anterograde manner from acardioplegic fluid pump 196 through inner lumen 180 indelivery cannula 172 into the ascending aorta upstream of the point at which the aorta is clamped. The cardioplegic fluid flows from the ascending aorta AA into the coronary arteries and paralyzes the myocardium. It should be noted that, when usingclamping device 110 withintegrated delivery cannula 120,endovascular delivery cannula 172 need not be utilized. However, it may be desirable to utilize such a cannula to facilitate pressure measurement, aspiration of air, fluids, thrombus, and other emboli from the aortic lumen, as well as supplementary delivery of cardioplegic fluid. - In addition, cardioplegic fluid may be delivered in a retrograde manner through a
retroperfusion catheter 272 positioned in the coronary sinus CS.Retroperfusion catheter 272 may be positioned, usually over a guidewire (not shown), from the neck through the internal jugular vein JV and superior vena cava SVC, or from the groin through a femoral vein V and the inferior vena cava IVC.Retroperfusion catheter 272 may have one or more balloons (not shown) at its distal end to enhance positioning and infusion of cardioplegia into the coronary sinus. Cardioplegic fluid may thus be infused through the coronary veins into the capillary beds, paralyzing the myocardium. - Following delivery of cardioplegic fluid into the aortic lumen, cardiac function will quickly cease. The patient is now prepared for an interventional procedure to be performed. A variety of thoracoscopic, endovascular, or open surgical procedures may be performed, including coronary artery bypass grafting, heart valve repair and replacement, septal defect repair, pulmonary thrombectomy, removal of atrial myxoma, patent foramen ovale closure, treatment of aneurysms, myocardial drilling, electrophysiological mapping and ablation, angioplasty, atherectomy, correction of congenital defects, and other interventional procedures. Less-invasive techniques for performing such procedures are described in commonly-assigned copending application Ser. No. 08/023,778, and application Ser. No. 08/163,241, both of which are incorporated herein by reference.
- When it is desired to restore cardiac function, infusion of cardioplegic fluid through
thoracoscopic delivery cannula 120,endovascular delivery cannula 172 and/orretroperfusion catheter 272 is discontinued. Blood, other fluids, air, thrombus, and other emboli within the heart or coronary arteries may then be aspirated through inner lumen 180 ofdelivery cannula 172, as well as throughvenous cannula 260 and/orpulmonary venting catheter 266.Release button 162 on clampingdevice 110 may then be depressed, causingneedle 124 to retract from aorta A and leaving a staple 126 (FIGS. 6A-6D) in the aortic wall to close the puncture created therein. If the clamping device utilized does not include a means for closing the aortic puncture, conventional thoracoscopic instruments may be used to suture or staple the aortic puncture closed, if necessary. -
Lever 94 on clampingdevice 110 may then be released, openingjaws device 110 is withdrawn from the thoracic cavity. Any trocar sleeves used in the procedure are then removed, and thoracoscopic incisions are sutured or stapled closed.Delivery catheter 172 andretroperfusion catheter 272 may be removed from the patient. Cardiopulmonary bypass is then discontinued, andarterial cannula 264,venous cannula 260, andpulmonary venting catheter 266 are removed from the patient. Vascular punctures are closed. - The clamps described above are suitable for clamping hollow body structures in a patient, and in particular the ascending aorta, while the proximal end of the clamp extends through a percutaneous intercostal penetration in the patient. The following preferred embodiments describe deployable clamps which have clamp positioners which are detachable from the clamps. In this manner, the clamp positioner can be removed so that increased visual access is provided and, furthermore, a trocar used to introduce the clamp is available for another instrument thereby advantageously minimizing the number of penetrations in the patient.
- FIGS. 17 and 18 illustrates a
clamp assembly 302 having aclamp 304 releasably connected to aclamp 306 positioner. Theclamp 304 includes first andsecond jaws jaws Jaw 310 is pivotally mounted tojaw 308 by apivot pin 316 which passes through abore 318 formed in ajaw extension 320 ofjaw 308. Pin 316 passes through abore 322 formed at the proximal end ofjaw 310. - Referring to FIGS.19-21,
clamp 304 also includes anactuator housing 324 slidably mounted tojaw extension 320. Theslidable actuator housing 324 moves thejaw 310 between open and closed positions through a pin and slot configuration, however, any other mechanical connection may be provided. Asecond pin 334 is fixed within asecond bore 336 formed of thesecond jaw 310 in an interference fit. The ends ofpin 334 reside withinslots 330 so that movement ofactuator housing 324 in the direction ofarrow 338 of FIG. 21 causes pin 334 to move upwardly withinslots 330 thereby pivotingjaw 310 upwardly from the closed position of FIG. 20 to the open position of FIG. 21. Thedistal end 326 ofactuator housing 324 circumscribesjaw extension 320 and anotherslot 330 formed therein. Slot 328 passes into theopen interior 332 ofactuator housing 324 to permit thejaw 310 to pass therethrough when in the open position of FIG. 21. -
Jaw extension 320 includes a set ofratchet teeth 340 for locking the jaws in the closed position. Theratchet teeth 340 are engaged by apawl 342 pivotally mounted within aslot 344 at apivot 345.Pawl 342 is biased by a spring, not shown, to pivot in a clockwise direction. Pawl is pivoted in a counterclockwise direction using theclamp positioner 306 to disengagepawl 342 fromratchet teeth 340. - Referring now primarily to FIGS. 17 and 22,
clamp positioner 306 includes an elongatehollow body 346 sized to fit within a trocar sleeve 348 (see FIG. 23) withclamp 304 mounted to the distal end ofclamp positioner 306.Hollow body 346 houses a pair of longitudinallyslidable manipulator rods Manipulator rods lug slots actuator housing 324 andjaw extension 320, respectively.Lugs slots distal end 366 ofhollow body 346 pivots pawl 342 in a counter-clockwise direction when thelugs slots jaw 310 and permits moving thejaws handles clamp 304 is locked again by rotating and pullingclamp positioner 306 so that thelugs slots pawl 342 and permittingpawl 342 to return to the position of FIG. 20. Theclamp positioner 306 is then preferably withdrawn from thoracic cavity TC throughtrocar sleeve 348 leavingclamp 304 in the patient - FIGS. 23 and 24 illustrate the use of a
deployable clamping assembly 304A to clamp the aorta AO. The embodiments discussed below with reference to FIGS. 23-33A have like parts referred to with like reference numerals. Aneedle 50 penetrates the aorta for delivering cardioplegic fluid into the patient for paralyzing the myocardium. Alternatively, cardioplegic fluid may be delivered through a cannula positioned within the aorta as shown in FIG. 8.Clamp 304A has a pair ofopposed jaws pivot 367.Jaws compression spring 368 by the engagement by a pair ofratchets 370 mounted tojaw extensions clamp positioner 306A has a pair ofmanipulator arms openings 376 injaw extensions jaws 310A, 312A onto pulmonary artery PA. Atether 373 extends between theclamp 304A and theclamp positioner 306A so that theclamp 304A can be easily located after theclamp positioner 306A is removed from the patient. A separate device (not shown) can be used to disengageratchets 370 to releasejaws clamp positioner 306A can be used to remove theclamp 304A. -
Clamp 304A is introduced through atrocar sleeve 348 in the closed position of FIG. 24.Clamp 304A and the portion of theclamp positioner 306A passing throughtrocar sleeve 348 are sized to fit within thetrocar sleeve 348 which preferably has a maximum internal dimension of about 20 mm by 32 mm although any size may be provided. The size oftrocar sleeve 348 is determined largely by the spacing between ribs R. The above described method may, of course, be performed using any of the clamps disclosed herein. - FIG. 25 illustrates a clamping
assembly 302B having aclamp positioner 306B and aclamp 304B having first andsecond jaws first jaw 310B is pivotally mounted to a threadedjaw extension 320B at apivot 316B whilejaw 308B is fixed.Jaws -
Clamp positioner 306B includes ahollow drive body 346B which houses a stabilizingrod 378. Thehollow drive body 346B actuates the jaws while the stabilizingrod 378 stabilizes the clamp assembly against the torsional forces produced by rotational actuation of therotatable drive body 346B. Theactuator housing 324B includes ashoulder 325 against which thejaw 310B abuts due to the force of the torsion spring (not shown). Thus, slidable movement of theactuator housing 324B, and consequentlyshoulder 325, moves the jaws between the open and closed positions. Thedrive body 346B has asquare opening 384 at the distal end which is configured to engage a squareouter surface 392 of the jaw extension for rotatably driving thejaw extension 320B. Thesquare opening 384 may have any other shape which is adapted for rotation. Thejaw extension 320B has threads which engage thehollow actuator housing 324B so that rotation of theactuator housing 324B moves theactuator housing 324B relative to thejaws rod 378 has a square shaft 382 (FIG. 26) at a distal end which matingly engages asquare hole 386 formed in thejaw extension 320B. The stabilizingrod 378 is coupled to ahandle 380 for preventing rotation of the stabilizingrod 378. Although thehandles handles - A
tether 327 is preferably attached to theclamp 304B at one end and extends through thedrive body 346B. Thetether 327 helps the user locate the clamp after theclamp positioner 304B is removed from the patient. A locking tab (not shown) is preferably provided at thehandle 380 for locking thetether 327 to thehandle 380. Thetether 327 is preferably locked to thehandle 380 so that theclamp 304B andclamp positioner 306B are coupled together when removing theclamp 304B from the patient. Thetether 327 may be provided with any of the clamps described herein. - The
clamp 304B is introduced into the thoracic cavity TC through atrocar sleeve 348 while in the closed position of FIG. 25. Whenclamp 304B is properly positioned, handle 380 is held stationary while theproximal end 394 ofhollow drive body 346B is rotated thereby moving theactuator housing 324B and permittingjaws jaws proximal end 394 ofhollow drive body 346B is rotated in the opposite direction to close thejaws clamp positioner 306B is preferably removed from the patient throughtrocar sleeve 348. When it is desired to remove the clamp, thetether 327 is used to locate the clamp and theclamp positioner 306B is used to remove theclamp 304B. - FIGS.28A-28C show three different views of a
clamp 304C which also uses a rotatable actuating element.Clamp 304C includes first andsecond jaws jaw surfaces Jaws -
Arms clamp base 396.Clamp base 396 has a threaded central hole through which a threadedshaft 398 passes. Theshaft 398 rotates within the threaded hole formed inbase 396 so that rotation displaces the shaft axially relative to the base. A clamp positioner similar to that shown in FIG. 25 is preferably used to rotate a hex-head 400 while preventingbase 396 from rotating. Aconnector 402 is coupled to a distal end of theshaft 398.Connector 402 is coupled to first andsecond jaws links shaft 398moves jaws - FIGS. 29A and 29B illustrate a
clamp 304D having a pair ofjaws jaw extensions jaws pivot point 408 and are normally biased to the open position of FIG. 29B with a spring or any other conventional biasing mechanism, not shown.Clamp 304D includes abase 396D having a threaded bore through which a threadedshaft 398D passes. Threadedshaft 398D is connected to awedge 410 at its outer end.Wedge 410 is sized to engage the opposed faces 412, 414 ofextensions jaws 308D. Thus,rotating shaft 398D, while maintainingbase 396D stationary, moveswedge 410 between the position of FIG. 29A, which closesjaws jaws 308D. - FIGS.30A-30C illustrate a clamping
assembly 302E including afirst jaw 308E having ajaw extension 320E housing theproximal end 416 of asecond jaw 310E.Jaw 310E is pivotally mounted tojaw extension 320E at apivot 418. Atorsion spring 420 is mounted aboutpivot 418 whichbiases jaws pawl 342E is pivotally mounted tojaw 310E.Pawl 342E includes a number ofteeth 340E which engage astationary tooth 422 carried byjaw extension 320.Teeth 340E are biased towardstooth 422 by atorsion spring 424. -
Clamp positioner 306B includes a first part 426 and a pair ofsecond parts arrow 430. Part 426 has ahook 432 at its distal end which engages aneye 434 injaw extension 320E. Withclamp positioner 306E in the orientation of FIG. 30A and thehook 432 mounted ineye 434, thesecond part 428 is configured to engage thesecond jaw 310E. Thesecond part 429 is moved in a distal direction to engagepawl 342E thereby pivotingpawl 342E away fromtooth 422 and permittingjaw 310E to pivot to the open position of FIG. 30B. - The above-described embodiments of clamping assembly302-302E all provide a clamp which is completely separable from the clamp positioner, apart from the tether, after being clamped onto a hollow body structure. Although it is preferred to provide a clamp positioner which is also used to retrieve the clamp after the medical procedure, it is within the scope of the present invention to provide a separate clamp remover which is used to remove the clamp after introduction with the clamp positioner. It also may be desired to provide the
tether 327 to the clamp which extends through the trocar sleeve. Tether 327 does not take up much room and does not hinder access to the target region but aids retrieval of the clamp by guiding the distal end of the clamp positioner to the clamp when removing the clamp from the patient. - The following embodiments disclose jaw actuating mechanisms which include a cable or hydraulic actuator. An advantage of the cable and hydraulic actuators described below is that they also do not take up much room in the trocar sleeve and, therefore, enhance visualization and permit introduction of other instruments into the patient through the same trocar sleeve.
- Referring to FIG. 31A, a clamping assembly302F having a
clamp 304F and aclamp positioner 306F is shown.Clamp 304F includes jaw surfaces 312F, 314F which are not parallel when the jaws are in the fully closed position of FIG. 31. The jaw surfaces 312F, 314F are covered with a resilient, ribbed material, having nesting troughs and grooves. This configuration may be useful when the hollow body structure being clamped has relatively thick walls (see FIG. 31E) so that when the hollow body structure is completely collapsed,jaws -
Clamp positioner 306F includes acoaxial cable 438 having an outer,hollow sheath 440 and aninner cable 442. The distal end 444 ofsheath 440 terminates at arecess 446 formed injaw extension 372F.Cable 442 passes throughjaw extension 372F and acompression spring 368F and is secured to thejaw extension 374F atball end 448.Clamp positioner 306F includes acable puller 450 having adistal end 452 against which aproximal end 454 ofsheath 440 rests.Cable 442 passes throughcable puller 450 and a second ball end 456 fits within a ball opening 458 on thehandle 460. Handle 460 is secured to thebase 462 ofcable puller 450 at apivot 464 and is biased to the position of FIG. 31A by thecompression spring 466. -
Coaxial cable 438 is preferably sufficiently rigid to enable the user to guideclamp 304F to the target location, often without the use of additional guiding structure, however, a guide rod or wire may also be used as disclosed below. Onceclamp 304F is adjacent to the body structure to be clamped, handle 460 is pressed againstbase 462 thereby pullingcable 442 and opening thejaws handle 460 is then released andspring 368F closesjaws 308F around the aorta.Ball end 456 may then be disengaged from ball opening 458 andsheath 440 can be removed from the patient through thetrocar sleeve 348 while leavingcable 442 within the patient. In this manner,cable 442 serves as a tether permitting easy and rapid employment ofcable sheath 440 againstclamp 304F while taking up very little space within the trocar sleeve and creating minimal interference at the target region. Alternatively, thecable sheath 440 andcable 442 may remain in the patient. As discussed above, the trocar sheath through which the cable passes may include a passageway for holding the cable so that the cable is not inadvertently actuated by another instrument passing through the same trocar. - Referring to FIG. 31B, a
clamp 304 G including jaws 308G is shown. A torsion spring 468 biases thejaws clamp 304G is substantially similar to theclamp 304F, however, thejaws jaws - FIG. 31C shows a
clamp 304 H having jaws Jaw 308H includes a pair ofslots 441 andjaw 310H includes a pair ofpins 443 for maintaining the parallel relationship betweenjaws Clamp 304H includes a pair of inwardly directed tips 472 at the end of eachjaw jaws Compression spring 368 H biases jaws cable 442 closesjaws latch 470 locks thejaws Latch 470 is biased towards the latched position of FIG. 31B by a coil torsion spring, not shown. To releaselatch 470,sheath 440 includes an axially movable latch engagement element, not shown. Alternatively, a separate latch release mechanism may be provided - FIG. 31D shows a clamp
304 I having jaws 308I, 310I which move parallel to one another as in the embodiment of FIG. 31C. Acable 442 is attached to acentral pivot 474 and a pair oflinks 476 so that pulling oncable 442 causespivot 474 to move proximally thereby openingjaws 308I, 310I. Thejaws 308I, 310I are biased closed by springs (not shown) coupled to the ends oflinks jaws 308I, 310I and, furthermore, limits the overall compression of the body part. A safety spring or other tension-sensitive element could be used alongcable 442 to limit the force exerted by thecable 442 for any of the cable actuated embodiments described herein. - FIG. 31E illustrates a
clamp 304J having a pair ofconcave jaws pivot 367J. The proximal ends ofjaw extensions links common pivot 484.Cable 442 is coupled to pivot 367J so that pullingcable 442 causes pivots 367J and 484 to be drawn towards one another thereby openingjaws pivot 367J to biasjaws jaws openings 488. The set screw limits how farjaws jaws 308J by positioning the set screw in the appropriate threadedopenings 488. FIG. 31F illustrates a relatively thick-walledhollow body structure 490, such as an aorta, captured betweenjaws - FIG. 32A illustrates a
clamp 304K actuated by aclamp positioner 306K having a hydraulic actuator.Links cylinder 492 bypivots 494.Cylinder 492 houses apiston 493 coupled to apiston rod 496. The distal end ofpiston rod 496 is connected to pivot 367K so that movement of the piston rod causesjaws Cylinder 492 is supplied with hydraulic fluid through ahydraulic line 498.Clamp positioner 306K includes asyringe 500 which supplies hydraulic fluid tohydraulic fluid line 498 through pressure-relief shut-offvalve 502. Although it is preferred to provide thesyringe 500, any other hydraulic actuator may be provided.Valve 502 is closed when the desired pressure is applied to thecylinder 492. To prevent excessive force on the body part,valve 502 limits the pressure of the hydraulic fluid. If desired, the pressure relief feature ofvalve 502 could be adjusted according to the procedure being conducted, the condition of the patient and other pertinent information. - FIG. 32B shows a
clamp 304L which is hydraulically actuated viahydraulic line 498 and hydraulic cylinder 492L. Application of hydraulic fluid throughline 498 to cylinder 492L extendspiston rod 496L so that aroller 504 presses againstjaw extension 372L and closesjaws pivot 367L andbias jaws - FIG. 33A illustrates a
clamp 304 M including jaws jaw surfaces inflatable balloons balloons hydraulic lines balloons - FIG. 34 illustrates a side-biting
clamp 304N clamping onto ablood vessel 510 in a manner to restrict but not prevent fluid flow through the blood vessel as suggested byarrow 512. Although all of the previous embodiments have been described in connection with occluding the clamped body structure, all of the clamps disclosed herein may also be used to partially occlude the body structure in a manner similar to theclamp 304N of FIG. 34. - Referring to FIG. 35, a
clamp assembly 600 is shown which includes aclamp 602 and ahandle 604. Thehandle 604 and a portion of theclamp 602 are shown in cross-section. Acable 606 and asheath 608 extend between theclamp 602 and handle 604. Thecable 606 is housed within thesheath 608 and is connected to acable puller 610. Thecable 606 is used for actuating theclamp 602 as described below. Thesheath 608 is held at afirst sheath holder 612 at thehandle 604 and at asecond sheath holder 614 at ananchor 616. Thecable 606 passes through theanchor 616 and is coupled to aslide 618 which is slidably coupled to theanchor 616. Thesheath 608 andcable 606 preferably has a length from the distal end of the handle to the proximal end of the clamp which is at least 6 inches, and more preferably at least 10 inches, so that the clamp can reach the internal mammary artery through an percutaneous intercostal penetration while the handle remains outside the patient's chest. Theslide 618 andanchor 616 will also be described in greater detail below. Thecable 606 preferably has a 0.018 inch outer diameter and is made of stainless steel. Thesheath 608 is preferably a 0.050 inch outer diameter coil spring made of stainless steel. A 0.0005 shrink tube made of polyester is placed over the coil spring to prevent stretching. Any other cable and sheath may be used without departing from the scope of the invention. Thesheath 610 andcable 606 advantageously permit the introduction of other instruments through the same instrument delivery member since thesheath 610 takes up little room in the instrument delivery member and can be moved to a convenient location which does not hinder access of other instruments through the same instrument delivery member. Thesheath 610 preferably has a maximum outer diameter of less than 0.080, and more preferably equal to or less than 0.050. - The
clamp 602 includes afirst jaw 620 and asecond jaw 622. The first andsecond jaws jaw member 624 having anatraumatic jaw surface 626. Thejaws jaws clamp 602 may also be configured with only thefirst jaw 620 being movable. Referring to FIGS. 40 and 41, side views of the first andsecond jaws second jaw 622 having thejaw member 624 attached. Thejaws third slots second slot 630 being oriented substantially perpendicular to the jaw surfaces 626. Thesecond slot 630 of the first andsecond jaws second slots 630 helps maintain the first and second jaw surfaces 626 parallel to one another throughout movement between the open and closed positions. The first andthird slots jaws jaw surface 626. Referring to FIG. 35, first, second and third pins 629, 631, 633 pass through the first, second andthird slots - Referring to the plan view of FIG. 42, the
jaws slot 634 for attaching thejaw members 624 to thejaws slots 634 include adetent 636 which engages a protrusion 639 (FIG. 43) in thejaw members 624 for securing thejaw member 624 to thejaws jaws jaw member 624 has aretention tooth 638 at the distal end which extends beyond thejaw surface 626. Theretention teeth 638 help retain a clamped body structure between thejaws jaws jaw member 624 also has a roundedbumper 640 at the distal end for minimizing trauma to the patient when theclamp 602 is introduced into the body. Thejaw member 624 advantageously provides theatraumatic jaw surface 626,bumper 640 andretention tooth 638 in an integral piece which is easily attached to the first andsecond jaws jaws jaws - Referring to FIG. 44, an enlarged cross-sectional view of the
jaws jaw members 624 is shown. Theretention teeth 638 are preferably offset so that theretention teeth 638 do not interfere with one another when thejaws jaw members 624 are preferably hollow to further cushion the clamped body structure. Thejaw members 624 are preferably made of silicone but may be formed of any other suitable material. - Referring to FIGS. 45 and 46, side and plan views of the
slide 618 are shown. Theslide 618 includes athroughhole 642 for receiving thecable 606. The distal end of thecable 606 preferably has an anchor (not shown) which prevents withdrawal of thecable 606 through thethroughhole 642. Theslide 618 includes first andsecond holes second sides second holes third slots second jaws second jaws slide 618 is moved. Theslide 618 also includesgrooves 652 extending between the first andsecond holes - Referring to FIGS. 47 and 48, side and plan views of the
anchor 616 are shown. Theanchor 614 includescentral guides 654 which are positioned in thegrooves 652 of theslide 618. Thecentral guides 654 andgrooves 652 cooperate to help maintain the linearly slidable relationship between theslide 618 andanchor 614. Thecentral guides 654 also includeholes 656 therethrough for receiving the second pin 631 which extends through thesecond slots 630 in the first andsecond jaws anchor 614 has a roundedproximal end 658 which facilitates withdrawal of theclamp 602 from the patient. Theproximal end 658 also has thesecond sheath holder 614 for receiving thesheath 606. Theanchor 614 also includes four arms 615, three of which are shown in FIGS. 47 and 48, which extend between thecentral guides 654 and theproximal end 658. - Referring again to FIG. 35, the
handle 604 includes a pair offinger engaging elements 660 positioned on opposite sides of acavity 662. Anactuator 664 is slidably disposed within thecavity 662 for actuating the first andsecond jaws actuator 664 is positioned between thefinger engaging elements 660 for easy manipulation with the thumb or palm of the hand. Although it is preferred to provide thefinger engaging elements 660 and centrally locatedactuator 664, thehandle 604 may have any other configuration such as a pistol-type handle with a trigger actuator. - A
spring 668 is positioned within thecavity 662 with thecable 606 extending through thespring 668. Thespring 668 provides a biasing force between thecable 606 and thehandle 604 for biasing thejaws cable puller 610 has a threadedexterior surface 670 which matingly engages a threadedinterior surface 672 of theactuator 664. Alternatively, theinterior surface 674 of theactuator 664 may be threadably coupled to theexterior surface 676 of thecable puller 610. Thehandle 604 also includes aguide 678 which receives thecable puller 610. Theguide 678 preferably has a square internal cross-sectional shape (not shown) and thecable puller 610 has a correspondingly sized square external cross-sectional shape (not shown) so that thecable puller 610 does not rotate within thecavity 662. - The spring force which biases the
jaws actuator 664 thereby changing the compression of thespring 668. Referring to FIGS. 35 and 37, rotation of theactuator 664 moves theactuator 664 relative to thecable puller 610 and thehandle 604. The clamping force of theclamp assembly 600 in FIG. 35 is low since thespring 668 is relaxed while the clamping force of the clamp assembly in FIG. 37 is high since thespring 668 is compressed. Although it is preferred to threadably couple thecable puller 610 andactuator 664 together, thecable puller 610 may be coupled to theactuator 664 and handle 604 in any other manner. For example thecable puller 610 may be rotatably coupled to thehandle 604, the actuator may be linearly stable on the cable puller, and/or thespring 668 may be a torsion spring or a cantilevered lever instead of a compression spring. - Referring to FIG. 36, the clamp assembly preferably includes an
introducer 680 for facilitating introduction of theclamp 602 into the patient. Theintroducer 680 has aclamp holder 682 which is releasably fixed to theclamp 602. Theintroducer 680 has a pair ofprongs 684 which engage a pair ofholes 686 in theclamp 602. The proximal end of theintroducer 680 has arib 688 which engages aslot 690 in thehandle 604. Theintroducer 680 also has amalleable shaft 681 which can be bent to a desired shape. Although it is preferred to releasably couple theintroducer 680 to thehandle 604, theintroducer 680 may be completely independent of thehandle 604. Referring to FIG. 49, theintroducer 680 has a length similar to the length of theclamp assembly 600 so that thesheath 610 is pulled taught when theintroducer 680 is coupled to theclamp 602 and handle 604. In this manner, theintroducer 680 retains theclamp 602 with theprongs 684. To release theclamp 602, therib 688 is disengaged from theslot 690 and theintroducer 680 is simply pulled from theclamp 602 with theprongs 684 sliding out of theholes 686. Theintroducer 680 may also include an actuator for positively attaching and releasing theclamp 602 to and from theclamp holder 682. Although it is preferred to provide theintroducer 680, theclamp 602 may also be positioned with a conventional medical instrument such as forceps or the like. - Referring to FIG. 50, the
clamp assembly 600 also preferably includes anindicator 692 which provides a relative indication of thespring 668 compression. Theindicator 692 extend through aslot 694 in thehandle 604 and a numerical scale indicates the relative clamping force. Referring to FIG. 51, theindicator 692 is received in acircumferential slot 696 in the distal end of theactuator 664. When theactuator 664 is rotated, theindicator 692 translates in theslot 696. Theclamp assembly 600 also preferably includes aclip 698 for securing thehandle 604 to a drape or curtain which covers the patient. - Referring to FIGS. 35, 37,39 and 49, operation of the
clamp 602 is now described in connection with clamping an internal mammary artery. Although clamping of the internal mammary artery is described as a preferred use of the clamping assembly, the clamp assembly may, of course, be used for clamping any other body structure. When thejaws slide 618 is biased toward the proximal end by thespring 668 and is positioned near the proximal end of theanchor 614. If a high clamping force is desired, theactuator 664 is rotated to the position of FIG. 37. If a low clamping force is desired, theactuator 664 is moved to the position of FIG. 35. Theclamp 602 is then mounted to theintroducer 680 as shown in FIG. 49 and theclamp 602 is introduced into the patient. When theclamp 602 is positioned near the internal mammary artery, theactuator 664 is depressed so that thecable 606 and slide 618 move distally relative to thesheath 610. The pin and slot configuration of thejaws anchor 614 cause thejaws clamp 602 is then moved so that the internal mammary artery is positioned between thejaws actuator 664 is then released so that thejaws rib 688 of theintroducer 680 is released from thehandle 604 and theintroducer 680 is pulled from theclamp 602 and removed from the patient. Thehandle 604 is then moved to a convenient location where it will not interfere with the medical procedure such as grafting of the internal mammary artery to a blocked coronary artery. After the procedure is completed, theactuator 664 is depressed to open thejaws clamp 602 is then simply pulled from the patient. An advantage of theclamp assembly 600 is that the clamping force may be adjusted during the procedure without requiring re-application of theclamp 602. If, for example, the clamped body structure is a blood vessel which is not fully occluded, the clamping force may be increased without releasing theclamp 602. Referring to FIG. 38, another advantage of the clamp assembly is that theretention teeth 638 can be used to retain the body structure even when thejaws actuator 664 is depressed to release theclamp 602 and permit blood flow through the internal mammary artery. - The
clamp assembly 600 advantageously provides aclamp 602 which may be actuated at a location remote from theclamp 602 and is particularly useful for temporarily clamping a body structure such as an internal mammary artery. Theclamp 602 may be positioned around the internal mammary artery with thecable 606 andsheath 610 extending through an instrument delivery member such as a trocar, cannula, retractor, or the like. Although it is preferred to provide the pin and slot configuration of the FIGS. 35, it is also within the scope of the present invention to use any of the other cable actuated clamps described above with theactuator 664. Conversely, any of the actuators described above may be used with theclamp 602 of FIG. 35. - While the clamps described have been described specifically with reference to aortic clamping and clamping of the internal mammary artery, it will be understood to those of ordinary skill in the art that the invention is useful in a variety of other interventional procedures as well. For example, the clamping device of the invention may be used for clamping, cannulation of, and infusing fluid into blood vessels other than the aorta, as well as hollow body structures such as the bowel, bile duct, colon, and various other tubular ducts and organs. Furthermore, all of the clamps are suited for the procedures described herein including use of the intraluminally positionable
delivery cannula 172 shown in FIGS. 7, 8, and 10-14 and the tether of FIGS. 23-25. In addition, although each of the preferred jaw shapes may be described with a particular actuating mechanism, any jaw shape may be used with the clamps and actuating mechanisms described herein and, in particular, curved and flattened tips will aid in blunt dissection. While the above is a complete description of the preferred embodiments of the invention, various alternatives, modifications and equivalents may be used. Therefore, the above description should not be taken as limiting the scope of the invention, which is defined by the claims.
Claims (20)
1. A method of clamping a structure in a patient, comprising the steps of:
providing a clamp, a cable puller, a flexible sheath, and a flexible cable, the handle having a first sheath holder and the clamp having a second sheath holder, the sheath extending between the first and second sheath holders, the cable being at least partially housed within the sheath and being coupled to the cable puller, the cable puller being adapted to displace the cable relative to the sheath, the clamp having a first jaw and a second jaw, the first jaw being movable relative to the second jaw between an open position and a closed position, the first jaw being coupled to the cable so that the first jaw moves between the open and closed positions when the cable is moved by the cable puller;
introducing the clamp into a patient;
moving the cable puller thereby displacing the cable relative to the sheath and moving the first jaw to the open position;
positioning a body structure of a patient between the first and second jaws after the moving step; and
closing the jaws around the body structure by moving the cable puller.
2. The method of , wherein:
claim 1
the providing step is carried out with an introducer releasably coupled to the clamp; and
the positioning step is carried out by manipulating the introducer so that the first and second jaws are positioned around the body structure.
3. The method of , further comprising the step of:
claim 2
disengaging the introducer from the clamp after the positioning step.
4. The method of , wherein:
claim 1
the providing step is carried out with both the first and second jaws being movable between the open and closed positions.
5. The method of , wherein:
claim 4
the moving step is carried out with the first and second jaws having jaw surfaces remaining substantially parallel to one another when moving between the open and closed positions.
6. The method of , further comprising the step of:
claim 1
adjusting a force biasing the first and second jaws toward the closed position.
7. The method of , wherein:
claim 1
the positioning step is carried out with the body structure being an internal mammary artery.
8. A clamp for clamping a body structure in a patient, comprising:
a handle having a first sheath holder;
a clamp having a second sheath holder, a cable holder, a first jaw and a second jaw, the first jaw being movable relative to the second jaw between an open position and a closed position, at least the first jaw being operably coupled to the cable holder for moving the first jaw between the open and closed positions;
a flexible sheath extending between the first and second sheath holders;
a flexible cable at least partially housed within the sheath; and
a cable puller movably coupled to the handle, the cable puller being configured to displace the cable relative to the sheath.
9. The clamp of , wherein:
claim 8
the second jaw is also movable between the open and closed positions relative to the first jaw.
10. The clamp of , wherein:
claim 9
the first and second jaws remain substantially parallel to one another when moving between the open and closed positions.
11. The clamp of , further comprising:
claim 8
a spring biasing the cable relative to the sheath, the spring biasing the first and second jaws toward the closed position.
12. The clamp of , further comprising:
claim 11
a spring force adjusting member contacting the spring and being coupled to the cable puller, the spring force adjusting member being configured to adjust a closing force of the first and second jaws.
13. The clamp of , further comprising:
claim 11
an actuator movably coupled to the handle, the actuator being connected to the cable puller and contacting the spring, the actuator being movable relative to the handle between a first position, in which a first clamping force is applied to the actuator by the spring when the jaws are in the closed position, and a second position, in which a second clamping force is applied by the spring when the first and second jaws are in the closed position, the first clamping force being larger than the second clamping force.
14. The clamp of , wherein:
claim 19
the introducer is releasably attached to the handle.
15. The clamp of , wherein:
claim 19
the introducer is malleable so that the introducer may be deformed.
16. The clamp of , wherein:
claim 8
the cable puller is linearly slidable relative to the handle;
the handle having means for preventing rotation of the cable puller.
17. The clamp of , further comprising:
claim 8
first and second links coupled to one another at a first pivot, the first and second jaws being coupled to one another at a second pivot;
the cable being coupled to at least one of the first and second pivots for moving the first jaw from the open position to the closed position.
18. The clamp of , wherein: the cable includes an end which is detachable from the clamp.
claim 8
19. The clamp of , further comprising;
claim 8
an introducer releasably attached to the clamp.
20. A clamp, comprising:
a clamp body having a distal end; and
a jaw member coupled to the clamp body, the jaw member having an atraumatic jaw surface and a bumper, the bumper extending substantially around a distal end for reducing trauma when the clamp is inserted into a patient, the bumper being integrally formed with the atraumatic jaw surface.
Priority Applications (1)
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US09/225,258 US6368340B2 (en) | 1995-04-03 | 1999-01-04 | Clamp assembly and method of use |
Applications Claiming Priority (5)
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US08/415,273 US5536251A (en) | 1993-02-22 | 1995-04-03 | Thoracoscopic devices and methods for arresting the heart |
US08/567,996 US5618307A (en) | 1995-04-03 | 1995-12-04 | Clamp assembly and method of use |
US08/595,568 US5626607A (en) | 1995-04-03 | 1996-02-01 | Clamp assembly and method of use |
US08/791,130 US5855590A (en) | 1995-04-03 | 1997-02-13 | Clamp assembly and method of use |
US09/225,258 US6368340B2 (en) | 1995-04-03 | 1999-01-04 | Clamp assembly and method of use |
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US08/791,130 Continuation US5855590A (en) | 1995-04-03 | 1997-02-13 | Clamp assembly and method of use |
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US09/225,258 Expired - Fee Related US6368340B2 (en) | 1995-04-03 | 1999-01-04 | Clamp assembly and method of use |
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US08/791,130 Expired - Lifetime US5855590A (en) | 1995-04-03 | 1997-02-13 | Clamp assembly and method of use |
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Also Published As
Publication number | Publication date |
---|---|
WO1997020506A1 (en) | 1997-06-12 |
AU1087497A (en) | 1997-06-27 |
US6368340B2 (en) | 2002-04-09 |
US5626607A (en) | 1997-05-06 |
US5855590A (en) | 1999-01-05 |
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