US20020029055A1 - Apparatus and method for tissue removal - Google Patents
Apparatus and method for tissue removal Download PDFInfo
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- US20020029055A1 US20020029055A1 US09/872,526 US87252601A US2002029055A1 US 20020029055 A1 US20020029055 A1 US 20020029055A1 US 87252601 A US87252601 A US 87252601A US 2002029055 A1 US2002029055 A1 US 2002029055A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
- A61B17/1635—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for grafts, harvesting or transplants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320016—Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes
- A61B17/32002—Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes with continuously rotating, oscillating or reciprocating cutting instruments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
- A61B17/1613—Component parts
- A61B17/1615—Drill bits, i.e. rotating tools extending from a handpiece to contact the worked material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
- A61B17/1613—Component parts
- A61B17/1631—Special drive shafts, e.g. flexible shafts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00969—Surgical instruments, devices or methods, e.g. tourniquets used for transplantation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2217/00—General characteristics of surgical instruments
- A61B2217/002—Auxiliary appliance
- A61B2217/005—Auxiliary appliance with suction drainage system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2217/00—General characteristics of surgical instruments
- A61B2217/002—Auxiliary appliance
- A61B2217/007—Auxiliary appliance with irrigation system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/71—Suction drainage systems
- A61M1/79—Filters for solid matter
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Abstract
Description
- 1. Technical Field
- The present invention relates to the field of tissue removal and tissue grafting. More particularly, t he present invention relates to an apparatus and method for the percutaneous cutting and removal of selected portions of tissue from a patient and the possible harvesting and implantation of the tissue portion in the donor.
- 2. Description of the Prior Art
- There are various known methods and apparatus for the cutting and removal of tissue fragments from a human. Each of these, however, suffers from one or more deficiencies.
- U.S. Pat. No. 4,832,683 shows an instrument for ultrasonic cutting of bones, with irrigation or suction. However, there is no suction while cutting, no removal of the cut bone or tissue, and no flexibility in the instrument.
- U.S. Pat. No. 4,265,231 shows apparatus f or drilling a curved hole having a flexible shaft confined in a rigid tubular sheath, but which shows no removal of cut bone or tissue.
- U.S. Pat. No. 4,541,423 shows apparatus for drilling a curved hole having a flexible shaft confined in a semirigid tubular sheath, but which shows no removal of cut bone or tissue.
- U.S. Pat. No. 4,589,414 shows a surgical cutting instrument with a reciprocatory cutting motion, but which has no removal of cut bone or tissue, and no flexibility in the instrument.
- U.S. Pat. No. 4,603,694 shows a rotating arthroscopic shaver with suction, but which is not flexible and which has no removal of cut bone or tissue.
- U.S. Pat. No. 4,751,922 shows a flexible medullary reamer with a plastic shaft and a guide rod, but which has no suction and no removal of the cut bone or tissue.
- U.S. Pat. Nos. 4,798,213, 4,649,918, and 4,142,517 show various apparatus for bone coring.
- The present invention is a percutaneous tissue removal apparatus including a flexible drill shaft and means for transmitting motion to the shaft. A cutting tip is mounted on the shaft to cut tissue fragments from the tissue. The tissue fragments are removed by suction along the flexible drill shaft to a location outside the body while cutting. One or more selected components of the removed tissue fragments may be collected for implantation, preferably into the body of the patient from whom they were removed. Because the drill shaft is flexible, the surgeon can guide the cutting tip into various locations within the tissue from a small (percutaneous) incision. The surgeon can cut around arcs or angles, rather than only being able to go in a straight line, to reach any desired location, and to avoid vital tissue which would otherwise be in the cutting path. For example, when removing unwanted tissue inside a knee joint the drill shaft can deform, and is therefore less likely to damage normal tissue or joint surfaces. None of these functions is possible with a straight line system.
- The present invention is a percutaneous tissue removal device and method. In the preferred embodiments described below, the apparatus and method are illustrated as used for removal of bone tissue, but such description is for illustrative purposes only. The invention is not limited to the removal of bone tissue and may be used for removal of cartilage, muscle, fetal tissue, etc. It may be used to break up and remove kidney stones, in the gall bladder for a stone or tumor, in the stomach, in the colon to remove a polyp or tumor, etc. It can reach spaces not currently available with the straight line systems currently available.
- A percutaneous tissue removal apparatus in accordance with the present invention includes a flexible drill shaft for insertion inside a tissue. A cutting tip is mounted on the drill shaft for cutting the tissue. Either rotating motion or reciprocating motion is transmitted to the drill shaft to move the cutting tip against the tissue to cut tissue fragments from the tissue. While cutting, the tissue fragments are removed by suction to a location outside the body. The drill shaft and cutting tip are small enough to be usable percutaneously. They may also be used for endoscopic, arthroscopic or fiberoptic or open surgery.
- Because the drill shaft is flexible, the surgeon can guide the cutting tip into various locations within the tissue from one percutaneous incision. The surgeon can cut around arcs or angles, rather than only being able to go in a straight line, to reach any desired location, and to avoid vital tissue which would otherwise be in the cutting path. The flexible drill shaft also allows the surgeon when working inside a bone, for example, to keep the cutting tip away from the harder outer cortical bone and to remove only the softer inner cancellous bone. None of these features is available with the current straight line cutting devices.
- The drill shaft may be made of metal, of polymeric material to reduce friction, or of a composite material. Extensive use of polymers in the drill shaft, its housing if provided, and the cutting tip area reduces friction substantially, thus requiring less energy and generating less heat within the tissue. The drill shaft is drivable by hand (for improved feel) or by motor, at variable speeds based on the need for the tissue removed.
- To provide for the collection of the tissue fragments to be harvested, the removal apparatus has an axially extending suction passage along the drill shaft through which the tissue fragments are removed. The suction passage has a smooth lining to keep the tissue fragments or graft material contained and to reduce friction of the harvested tissue fragments. This lining may be the inside diameter of the flexible drill shaft itself, or may be a separate liner sleeve which can be removed and disposed of when it becomes unsanitary or clogged, without having to remove the drill shaft and cutting tip. Alternatively, if a separate guide sleeve or guide rod is used the suction passage may be formed between the drill shaft and the guide sleeve or guide rod. In such a case, the drill shaft may be solid rather than hollow.
- The cutting tip is made of a material which is harder than the material to be cut. The cutting tip may be slightly larger in diameter than the drill shaft. The cutting tip may be made of a polymeric material or a composite material. Alternatively, the cutting tip may be made of a ceramic material. The cutting tip is separable from the drill shaft, and several different cutting tips may be provided in varying hardnesses, so that the surgeon can selectively remove various portions of tissue as desired.
- By virtue of its flexibility, the flexible drill shaft, when removing bone tissue, may stay within the cortical confines of the bone. Alternatively, it may work with a guide device to control the location of the cutting tip within the bone. The guide means may be a guide rod extending within the flexible drill shaft, or a hollow guide sleeve outside the flexible drill shaft. The guide rod or guide sleeve may be rigid in a particular shape, to fit a particular application; or it may be bendable into a particular shape which it will hold; or it may be selectively rigidifiable into a particular shape in situ. The guide means may include structure for positioning the tip of the flexible drill shaft. The guide means may also be inserted into a separate flexible tube system to guide it to a specific location, then removed, allowing the flexible drill to be inserted.
- Fluid may be injected through the flexible drill shaft to a location adjacent the cutting tip to increase the efficiency of the tissue removal and to limit thermal necrosis. Alternatively, a fluid injection passage may extend axially along the flexible drill shaft, the drill shaft. Alternatively, fluid may be injected through the suction passage, alternating with the suction. The fluid injection may be constant or it may be pulsatile in nature. If fluid injection is used, centrifuging of the harvested material may be performed.
- Means for collecting one or more selected components of the harvested tissue fragments may include a known trap or filter connected to the outlet of the suction passage. Removed tissue may be centrifuged to separate its components. Thus, the tissue fragments are not merely removed from the body and may be harvested for implantation of the fragments, preferably into the body of the patient from whom they were removed. In order to maintain the sterility of the tissue removed, the entire suction apparatus including the suction passage and the trap or filter is sterilized, and, if necessary, is disposable.
- With the present invention all work is done by going percutaneously through the skin to a specific tissue area to minimize the damage to skin, muscle, and bone. For example, when removing bone tissue, trauma is limited to a small opening in the hard outer structural cortical bone, limiting postoperative bleeding from the bone which is difficult to stop, because the small operative hole can easily be plugged after the grafting procedure is completed, preventing postoperative bleeding into soft tissue. There is only intraosseous bleeding, so that fewer complications, and less pain, are likely to arise. The operation does not create stress risers which would weaken the bone. Thus, the present invention provides a safe and efficient way to collect and reuse a patient's own tissue.
- Human tissue grafting works best using the patient's own tissue as donor material. Therefore, the harvested tissue may be implanted in the donor's own body for grafting. To implant one or more selected components of harvested bone fragments, for example, a cannula is inserted through the skin and muscle to the area of the bone where the graft is to be placed. A drill or curette is then used to remove a portion of the outer cortical bone. A curette or probe is inserted through the cannula to clear out the area where the graft is to be placed, either in open surgery or through X-ray guidance in percutaneous surgery. The harvested tissue fragments may be packed or compressed into a plug of tissue graft material, of a specific shape, with or without blood or fibrin for adhesion. Or, a retaining material such as a biodegradable mesh may be used to hold the graft material together as a unit. The graft material and its retaining material are then inserted at the graft location in the bone. Alternatively, the graft material is inserted and then sealed in place with a mass of formable polymeric material inserted over the graft material to hold the graft together in position.
- A method of percutaneous tissue removal in accordance with the present invention includes the steps of placing within a tissue mass a flexible drill shaft having mounted thereon a cutting tip for cutting the tissue; transmitting motion to the drill shaft to move the cutting tip against the tissue to cut tissue fragments from the tissue; and removing the tissue fragments by suction to a location outside the tissue mass while cutting the tissue. The method may further include the step of controlling the location of the cutting tip within the tissue with a guide rod, the step of collecting one or more selected components of the harvested tissue fragments, and/or the step of implanting the fragments into the body of the patient from whom they were removed.
- Further features of the present invention will become apparent to those skilled in the art to which the present invention relates from reading the following specification with reference to the accompanying drawings, in which:
- FIG. 1 is a schematic view of a tissue removal system in accordance with the present invention and including a flexible drill;
- FIG. 2 is a schematic view of a hand-powered flexible drill for use in the system of FIG. 1;
- FIG. 3 is a schematic view of a portion of a hollow flexible drive shaft for the flexible drill;
- FIG. 4 is a schematic view similar to FIG. 3 and showing a guide rod inside the hollow flexible drive shaft;
- FIG. 5 illustrates a portion of a flexible drill including a hollow flexible inner cutting shaft within a flexible outer sleeve and a suction passage between the two shafts;
- FIG. 6 is a view similar to FIG. 5 with a suction passage within the inner shaft;
- FIG. 7 illustrates a portion of a flexible drill including a solid flexible inner cutting shaft within a flexible outer sleeve and a suction passage between the two shafts;
- FIG. 8 illustrates a portion of a flexible drill including a solid formable inner guide rod within a flexible outer cutting sleeve and a suction passage between;
- FIG. 9 illustrates a portion of a flexible drill including a hollow flexible inner cutting shaft within a solid formable outer sleeve and a suction passage between;
- FIG. 10 is a view similar to FIG. 9 with a suction passage within the inner shaft;
- FIG. 11 illustrates a portion of a flexible drill including a solid flexible inner cutting shaft within a solid formable outer sleeve and a suction passage between;
- FIG. 12 illustrates a portion of a flexible drill including a relatively flexible portion between two relatively rigid portions;
- FIG. 13 illustrates the use of a liner sleeve in a suction passage;
- FIG. 14 is a view illustrating a number of different cutting tips usable with the flexible drill;
- FIGS. 15 and 16 are schematic views illustrating the provision of a plurality of separately inflatable bladders as a guide mechanism for a flexible structure and the operation of a guidance system for locating the tip of the flexible structure;
- FIGS. 17 and 17A are schematic views illustrating the forming of harvested tissue fragments into a compressed plug suitable for implantation;
- FIG. 18 is a schematic view illustrating the implantation of harvested bone fragments using a polymeric mesh as a retainer; and
- FIGS. 19 and 19A are schematic views illustrating the implantation of harvested tissue fragments using a formable polymeric sealant as a retainer.
- The present invention is described herein with reference to a percutaneous bone removal and harvesting apparatus and method. It should be understood that the present invention is not limited to the removal of bone tissue, but is useful in the removal of any hard or soft tissue in the body such as excess, unwanted, or tumorous tissue or tissue used for reimplantation or grating.
- A percutaneous bone removal apparatus10 (FIG. 1) in accordance with the present invention includes a
flexible drill 12. Theflexible drill 12 has aflexible shaft 14 and a cuttingtip 16 at the distal end of theshaft 14. The proximal end of theflexible shaft 14 is connected by ahousing 18 to a motor orother power source 20 to provide rotational motion or reciprocating motion in a manner known in the art. Alternatively, thedrill 12 may have an angled drive, such as 90° drive or any angle, with the motor drive connected at an angle to the longitudinal extent of the suction and cutting apparatus. - Control means indicated schematically at21 may include one or more switches or valves to turn on or off the suction, irrigation, and motor drive. control A
fluid injection source 22 is connected by afluid injection line 24 to thehousing 18 of theflexible drill 12. Asuction source 26 acts through a trap or filter orstrainer 28 and asuction line 30 to provide suction capabilities for theflexible drill 12. - FIG. 2 illustrates a
flexible drill 12 a in which thehousing 18 a is connected to ahand controller 20 a. Thehand controller 20 a allows the surgeon to operate theflexible drill 12 a by hand, imparting either rotational or reciprocating movement to the flexible shaft 14 a and cuttingtip 16 a. - FIG. 3 illustrates a portion of a basic version of a flexible drill having a cutting
tip 16 mounted on aflexible drive shaft 31. Thedrive shaft 31 has anouter surface 32 and aninner surface 34 defining a longitudinally extendingsuction passage 36. The cuttingtip 16 has a cutting edge 40 and anopening 38 through which tissue fragments cut by the cuttingtip 16 may be aspirated. The tissue fragments are drawn through thesuction passage 36 in theflexible drive shaft 31 and thence into the suction line 30 (FIG. 1) for collection in the trap or filter orstrainer 28. - FIG. 4 illustrates the use of a pre-inserted guide rod42 with a flexible drill of the present invention. The guide rod 42 extends through the
suction passage 36 of theflexible drive shaft 31. The guide rod 42 may be any suitable structure including a K-wire or other known device. The cuttingtip 16 may have a centrally located opening in its distal end to allow insertion of the flexible drill over the guide rod 42. The guide rod 42 is first placed in the body, then the flexible drill is inserted over the guide rod 42 and guided to the location from which tissue is to be harvested. - FIG. 5 illustrates an embodiment of a flexible drill having an outer sleeve44 circumscribing a flexible drill shaft 41. The flexible outer sleeve 44 may be formed of a metal or composite material or may be formed of a polymeric material which may be the same as or different from the material of the flexible
inner cutting shaft 31. The outer sleeve 44 is fixed (non-moving) to minimize tissue damage. Asuction passage 46 is defined between the outer surface of the flexibleinner shaft 31 to which the cutting tip is attached, and the inner surface of the flexible outer sleeve 44. Alternatively, as shown in FIG. 6, a suction passage 48 may be defined within the flexibleinner cutting shaft 50. In this case, the outer surface of the flexibleinner shaft 50 is preferably, as illustrated in FIG. 6, in close proximity to the inner surface of the outer sleeve 44 to increase stability. The use of polymeric materials for both theinner shaft 50 and the outer sleeve 44 provides for reduced friction between the sleeve 44 and theshaft 50 for ease of operation and reduced heat generation. - FIG. 7 illustrates an alternate embodiment of the apparatus of FIG. 5 in which the flexible
inner cutting shaft 52 is formed as a solid shaft rather than a hollow shaft. The harvested tissue fragments travel through thesuction passage 46 between theinner shaft 52 and the outer sleeve 44. - FIG. 8 illustrates apparatus similar to FIG. 7 in which a fixed (non-moving)
inner shaft 54 is made of a solid, formable, material and the cutting tip is mounted on a flexible rotatingouter sleeve 56. Suction is drawn through asuction passage 58 between theshaft 54 and thesleeve 56. Theinner shaft 54 is made from a semi-rigid material which is bendable to a desired curvature, at the use site, to select the curvature of the hole to be drilled, and which is rigid enough to retain that curvature in use while thedrill shaft 56 rotates around it. Such material is disclosed in U.S. Pat. No. 4,541,423, the disclosure of which is incorporated herein by reference. - FIGS. 9, 10 and11 illustrate embodiments of the flexible drill of the present invention in which a flexible inner cutting shaft, which may be hollow or solid, is disposed within a non-moving formable outer sleeve. The formable
outer sleeve 60 is made of a semi-rigid bendable shape retaining material as described above with reference to FIG. 8. In FIG. 9, a hollow flexibleinner cutting shaft 62 is disposed within theouter sleeve 60 and defines therebetween asuction passage 64. In FIG. 10, a hollow flexibleinner cutting shaft 66 is disposed in close proximity to and within theouter sleeve 60, with asuction passage 68 formed within the flexibleinner cutting shaft 66. In FIG. 11, a solid flexibleinner cutting shaft 70 is disposed within theouter sleeve 60, defining therebetween asuction passage 72. - FIG. 12 illustrates a portion of a
flexible drill shaft 80 in accordance with the present invention in which a pair of relativelyrigid drill portions flexible drill portion 86. The relativelyrigid drill portion 82 includes anouter sleeve 88, aninner shaft 90, and asuction passage 92 therebetween. The relativelyrigid drill portion 84 includes anouter sleeve 94 like theouter sleeve 88, aninner shaft 96 like theinner shaft 90, and asuction passage 98 therebetween. Thedrill portion 86 includes a relatively flexibleinner shaft portion 100 disposed within a relatively flexibleouter sleeve portion 102, defining therebetween asuction passage 104. The relatively flexibleinner shaft portion 100 connects the relatively rigidinner shaft portions outer sleeve portion 102 connects the relatively rigidouter sleeve portions suction passage 104 in the relatively flexibledrill shaft portion 86 connects thesuction passages flexible drill 80 may have a cutting tip mounted thereon. Thus, with a flexible drill shaft made in this manner, it is not necessary that the entire drill shaft be made of flexible materials, but rather “joints” such as are formed by the relativelyflexible portion 86 may be placed along the longitudinal extent of a relatively rigid drill shaft as desired. - FIG. 13 illustrates how a disposable single-
use liner sleeve 110 may be used in a flexible drill of the present invention. Theliner sleeve 110 shown in FIG. 13 is located within anouter sleeve 112 and is shown about a guide rod orguide wire 114. Suction is drawn through a passage 116 within theliner sleeve 110. The disposable single-use liner sleeve 110 provides an absolutely sterile environment through which harvested tissue fragments may pass. Theinner surface 118 of theliner sleeve 110 is extremely smooth in order to facilitate passage of the harvested tissue fragments therethrough. It should be understood that a liner sleeve like theliner sleeve 110 may be used with any suitable flexible drill shaft configuration in accordance with the present invention, and not merely with the configuration shown in FIG. 13. - FIG. 14 illustrates several different cutting tips which may be attached in a known manner to a flexible drill shaft in accordance with the present invention. The technology for the cutting tips is not specific to the present invention, but rather the cutting tips may be designed in accordance with known principles.
- The cutting tip120 (FIG. 14) has a
cutting edge 122 at least partially defining anopening 123 through which suction is drawn. The cuttingtip 124 includes a plurality of cuttingedges 126 defining a plurality ofsuction openings 128 disposed along the outer circumferential portion of thecutting tip 124. The cuttingtip 130 is similar to thecutting tip 124 but includes cuttingedges 126 a andsuction openings 128 a which extend to the end of thecutting tip 130. Furthermore, the cuttingtip 130 is blunt rather than sharp, to avoid perforation of tissue, such as bones. - The
cutting tip 132 has aspiral cutting edge 134 defining aspiral suction opening 136. The cuttingtip 138 has at least one longitudinally extendingcutting edge 140 at least partially defining a longitudinally extendingsuction opening 142. The cuttingtip 143 is formed as a burr with fluted cutting edges 144 andsuction openings 145, and is especially suited for shaving operations such as removal of bone spurs, etc. The cuttingtip 146 hastwin cutting edges suction opening 149. The cutting edges 157 and 148 can be configured with the leading edge to grab the tissue and the trailing edge to cut the tissue. - The configuration of a cutting tip for use in accordance with the present invention is a design choice within the skill of the art. The goals to be met are proper cutting and suction capabilities, controllability and shape so as to avoid unwanted damage to areas of tissue not to be cut. For example, when removing the softer cancellous portion of bone, the cutting tip may be made of a material which is harder than the cancellous material of the bone but softer than the cortical portion of the bone to avoid damage thereto. Metal may be useful, and suitable polymers are also readily available. Ceramic materials and composites are also suitable. Also, the cutting tip may be arranged as a rotating flexible shaft within a fixed flexible outer shaft, with a cutting edge on the rotating shaft to cut tissue off against the fixed edge. In such a case, the apparatus may be advantageously configured with one shaft being metal and the other polymeric, to minimize friction and heat buildup.
- FIGS. 15 and 16 illustrate an alternate guidance system for positioning a
flexible drill shaft 150 and its associated cutting tip. Disposed within thesleeve 150 is aguidance mechanism 152 including a plurality of inflatable elements spaced serially. The inflatable elements, when inflated, rigidify and become straight, while when in the deflated condition they are soft and flexible and may be curved or bent. Thus, as seen in FIG. 15, both the inflatable elements designated 154 and theinflatable elements 156 are curved. In FIG. 16, theinflatable elements 154 have rigidified and straightened, while theinflatable elements 156 remain in their curved position. The inflatable elements may also be accordion shaped, expanding in length as they are inflated. Themechanism 152 may be augmented with a known cable guidance system. - By selectively and individually controlling the rigidification of any or all of the inflatable elements of the
mechanism 152, theinflatable mechanism 152 and its associatedouter sleeve 150 may be selectively formed into almost any desired shape or position. Suitable control and valving apparatus is provided for controlling the inflation of the inflatable elements. Such apparatus may be, when only a few elements are present, a simple mechanical valving apparatus. When more elements are present, or more sophisticated or complex control thereof is desired, a microprocessor may be used to control the inflation of each segment. Separate inflation and deflation lines can be used, or one line can, by alternating valving, serve both functions. In such case, the control signals may be multiplexed down the structure via electric wire, optical fiber, or radio control, for example. - At the distal end of the
mechanism 152 is atip guidance mechanism 160 including a plurality ofinflatable members 162. Theinflatable members 162 when in a deflated condition are flexible and relatively straight. When inflated, as shown in FIG. 16, themembers 162 assume a preformed shape which may be curved or straight and which is illustrated herein as a curved shape, bending radially outwardly to engage the surface ofadjacent tissue 164 and curve the end of the device into an appropriate position. Themembers 162 may be constructed, using known principles, to assume any desired shape. By controlling the positioning of one or more of theelements 162, thetip portion 168 of theguidance mechanism 152 may be selectively placed in any position relative to thetissue 164, thus positioning the end of thesleeve 150. The air bladder guidance system as described may be used in conjunction with a flexible tube separate from the flexible drill shaft, order to guide the flexible tube to a specific location and position it there, thereafter removing the guidance system and allowing a flexible drill to be inserted. - Means for collecting one or more selected components of the harvested tissue fragments includes a mechanism28 (FIG. 1) which may be a known trap or filter connected to the outlet of the
suction passage 30. Removed tissue may also be centrifuged if necessary or desired, keeping the components such as bone, cells, and blood and discarding fluid. These components and connections, and their uses, are well known in the art and thus are not described herein in greater detail. The harvested tissue fragments are not merely removed from the body of the patient, but are also collected in thestructure 28 and thus harvested or saved for later implantation of the fragments, preferably into the body of the patient from whom they were removed. Such harvesting and implantation are desirable because human tissue grafting works best using the patient's own tissue as donor material. - In preparing the harvested graft material for implantation, the tissue fragments alone are spun or compressed (see FIG. 17) to form them into the desired shape. When the tissue is harvested, blood and blood clots are often drawn along with the tissue fragments. The blood component fibrin is a sticky clotting component, and can be used to aid in holding the tissue fragments together for implantation. Thus, the blood can be is separated from the tissue fragments and then spun to separate the fibrin for use with the tissue fragments. Alternatively, the entire mass of tissue fragments and blood is compressed into a specific shape to form the mass into a specific, appropriate shape for implantation into the body.
- The surgeon can also place other substances into the graft material to be implanted, such as other tissue graft material, collagen, antibiotics, or ceramic hydroxyapatite or tricalcium phosphate to aid in bone ingrowth. In such a case, when the blood or fibrin is used also, the graft has the adhesive qualities of the blood or fibrin and the biological properties of the bone (or other) tissue, along with the appropriate medical properties of any other material included.
- Harvested tissue fragments before implantation are preferably packed or compressed into a plug of tissue graft material. Alternatively, the tissue fragments may be left in a more loose state, or only certain selected cells, components, or tissue fragments are used. Any suitable means of packing or compressing fragments may be used. FIG. 17 illustrates schematically a simple apparatus for doing so. As viewed in FIG. 17, the harvested
tissue pieces 170 are placed into a form ormold 172 and then compressed by amovable compressor 174 to form aplug 176 of a desired shape or size. Unwanted fluid drains out through one or morefluid outlets 178, while the graft, cells, fibrin, and blood clot tissues remain within theform 172. - To implant one or more selected components of the harvested tissue fragments, for example in grafting bone tissue onto a bone, a
cannula 180 is inserted through theskin 182 andmuscle 184 to the area of thebone 186 where the graft is to be placed. A curette or probe is then inserted through thecannula 182 to clear out thearea 188 where the graft is to be placed. - The harvested tissue fragments are compacted or compressed into a
plug 190 of tissue graft material. A retaining material such as a known biodegradable or otherpolymeric mesh 192 is then used to hold thegraft material 190 together as a unit. The retaining material may also be a sac of biodegradable material used to hold the graft material. The sac can be closed by a clamp or by crimping or heat sealing. Thegraft material 190 and its retainingmaterial 192 are then inserted into the graft area of the bone. Thecannula 180 may then be removed. Alternatively, the tissue graft material may be held in place by a mass of biodegradable or other polymeric material used as a sealant for the opening in thebone 186. The graft material can be compressed or spun into a specific shape. Thus, if an implant is needed to fit a specific shape of bone defect, the graft material can be formed in the shape needed and packed directly into the bone gap. - The bone graft material may also be implanted in the loose condition as described above. The
bone graft material 194, if loose, can be inserted through afunnel 196 and asleeve 198 located within thecannula 180, to thearea 188 to be grafted. It is then packed in place as desired using a suitable instrument. Next, aninjector 200 is used to inject a mass of flowable biodegradable or otherpolymeric material 202 for use as a sealant to seal thebone graft material 194 in position. The use of a flowable biodegradable material is preferable in that it allows the surgeon to form in situ a custom shaped sealant plug to seal the opening in the tissue graft area, which will eventually resorb as new tissue grows into its place. - The apparatus may include, as noted above, fluid injection means22 and 24 for injecting fluid through the flexible drill to a location adjacent the cutting tip to aid in cutting and removal of the harvested tissue fragments. For example, in the drill shaft structure illustrated in FIG. 5, fluid may be injected through a fluid injection passage 204 within the flexible
inner cutting shaft 31, while suction is drawn in the opposite direction through thesuction passage 46. Alternatively, the suction may be intermittently discontinued and fluid may be injected through the suction passage, alternating with the suction. The fluid injection may be constant or it may be pulsatile in nature. - The present invention thus provides a method of percutaneous tissue removal which includes the steps of placing adjacent to a tissue mass a
flexible drill shaft 14 having mounted thereon a cuttingtip 16 for cutting the tissue; transmitting motion to thedrill shaft 14 to move the cuttingtip 16 against the tissue to cut tissue fragments from the tissue; and removing the tissue fragments by suction to a location outside the tissue mass while cutting the tissue. The method may further include the step of controlling the location of the cutting tip within the tissue with a guide mechanism, the step of collecting one or more selected components of the harvested tissue fragments, and/or the step of implanting the fragments into the body of the patient from whom they were removed. - From the above description of the invention, those skilled in the art will perceive improvements, changes and modifications. Such improvements, changes and modifications within the skill of the art are intended to be covered by the appended claims.
Claims (35)
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US10/005,017 Expired - Fee Related US6652532B2 (en) | 1990-06-28 | 2001-12-04 | Tissue repair method |
US10/004,905 Expired - Fee Related US6835198B2 (en) | 1990-06-28 | 2001-12-05 | Apparatus and method for tissue removal |
US10/044,388 Expired - Fee Related US6543455B2 (en) | 1990-06-28 | 2002-01-11 | Cell harvesting method |
US10/059,569 Expired - Fee Related US6607534B2 (en) | 1990-06-28 | 2002-01-29 | Tissue engagement method |
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US08/353,494 Expired - Lifetime US5577517A (en) | 1990-06-28 | 1994-12-09 | Method of grafting human tissue particles |
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US10/044,388 Expired - Fee Related US6543455B2 (en) | 1990-06-28 | 2002-01-11 | Cell harvesting method |
US10/059,569 Expired - Fee Related US6607534B2 (en) | 1990-06-28 | 2002-01-29 | Tissue engagement method |
US10/104,250 Expired - Fee Related US7134437B2 (en) | 1990-06-28 | 2002-03-22 | Method for utilizing human tissue |
US10/233,889 Expired - Fee Related US6592531B2 (en) | 1990-06-28 | 2002-09-03 | Surgical instrument positioning system |
US10/233,866 Abandoned US20030009147A1 (en) | 1990-06-28 | 2002-09-03 | Biodegradable sac and method of using same |
US10/233,865 Expired - Fee Related US6719803B2 (en) | 1990-06-28 | 2002-09-03 | Method for forming and implanting a grafting material containing tissue |
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US5577517A (en) | 1996-11-26 |
US6592531B2 (en) | 2003-07-15 |
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US20030009147A1 (en) | 2003-01-09 |
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US6174313B1 (en) | 2001-01-16 |
US6468289B1 (en) | 2002-10-22 |
US6835198B2 (en) | 2004-12-28 |
US7896880B2 (en) | 2011-03-01 |
US20030009237A1 (en) | 2003-01-09 |
US20020099401A1 (en) | 2002-07-25 |
US20020055755A1 (en) | 2002-05-09 |
US20020091403A1 (en) | 2002-07-11 |
US5403317A (en) | 1995-04-04 |
US20020045903A1 (en) | 2002-04-18 |
US6607534B2 (en) | 2003-08-19 |
US6543455B2 (en) | 2003-04-08 |
US5935131A (en) | 1999-08-10 |
US6719803B2 (en) | 2004-04-13 |
US7134437B2 (en) | 2006-11-14 |
US20020082631A1 (en) | 2002-06-27 |
US6652532B2 (en) | 2003-11-25 |
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