US20030014100A1 - Balloon catheter with stent and method for manufacturing it - Google Patents

Balloon catheter with stent and method for manufacturing it Download PDF

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Publication number
US20030014100A1
US20030014100A1 US10/140,479 US14047902A US2003014100A1 US 20030014100 A1 US20030014100 A1 US 20030014100A1 US 14047902 A US14047902 A US 14047902A US 2003014100 A1 US2003014100 A1 US 2003014100A1
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United States
Prior art keywords
balloon
relief structure
stent
winding
counter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/140,479
Inventor
Hendrik Maria Meens
Derk Trip
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CR Bard Inc
Original Assignee
Blue Medical Devices BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL1018018A external-priority patent/NL1018018C2/en
Application filed by Blue Medical Devices BV filed Critical Blue Medical Devices BV
Assigned to BLUE MEDICAL DEVICES B.V. reassignment BLUE MEDICAL DEVICES B.V. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MEENS, HENDRIK JOZEF MARIA, TRIP, DERK
Priority to US10/290,603 priority Critical patent/US20030125761A1/en
Publication of US20030014100A1 publication Critical patent/US20030014100A1/en
Assigned to C.R. BARD, INC. reassignment C.R. BARD, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BLUE MEDICAL DEVICES BV
Priority to US11/555,466 priority patent/US8257418B2/en
Priority to US13/600,342 priority patent/US8784470B2/en
Priority to US14/310,175 priority patent/US9993359B2/en
Priority to US15/952,576 priority patent/US20180228631A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958Inflatable balloons for placing stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1027Making of balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1027Making of balloon catheters
    • A61M25/1038Wrapping or folding devices for use with balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958Inflatable balloons for placing stents or stent-grafts
    • A61F2002/9583Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1027Making of balloon catheters
    • A61M25/1029Production methods of the balloon members, e.g. blow-moulding, extruding, deposition or by wrapping a plurality of layers of balloon material around a mandril
    • A61M2025/1031Surface processing of balloon members, e.g. coating or deposition; Mounting additional parts onto the balloon member's surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1086Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1002Balloon catheters characterised by balloon shape
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49826Assembling or joining

Definitions

  • the present invention relates to a balloon catheter comprising a catheter tube, an inflatable balloon which at its ends is attached to the catheter tube and a stent attached around the balloon, wherein the stent extends at least in part along the length of the balloon.
  • the invention further relates to a method of manufacturing a balloon catheter.
  • Balloon catheters of this type are generally known and are used for dilating vessels and lumina and for placing the stent in the dilated vessel or lumen.
  • the balloon catheter In order to pass the balloon catheter easily and safely through the vessels and lumina and to position it at the required place for dilatation, it is important that the balloon catheter has a small profile (outer diameter) and is sufficiently flexible.
  • the object of the invention is therefore to provide an improved balloon catheter.
  • the balloon catheter according to the invention is characterized in that, in an uninflated state, at least the outside surface of the balloon that is not covered by the stent is provided with a relief structure which in an inflated state of the balloon is substantially disappeared.
  • the required relief structure may have different embodiments, but preferably comprises at least one groove that extends at least transversely in the longitudinal direction of the balloon in order to give the catheter the required flexibility in a direction transverse to the longitudinal direction thereof.
  • the groove preferably extends at a predetermined angle with respect to the longitudinal direction of the balloon. According to a preferred embodiment, the groove extends helically from one end to the other end of the balloon, over the outside surface thereof.
  • the relief structure comprises two or more grooves that extend helically from one end to the other end of the balloon, crossing each other. Tests have shown that with such a relief structure a very flexible balloon catheter is obtained which also has a relatively low profile.
  • the invention also relates to a method for producing a balloon catheter comprising attaching the ends of an inflatable balloon to a catheter tube and placing a stent around the balloon, whereby according to the invention at least the outside surface of the balloon not covered by the stent is provided with a relief structure.
  • the outside surface of the balloon is first provided with the relief structure and then the stent is attached around the balloon.
  • An additional advantage of this embodiment is that a better fixing of the stent to the balloon is achieved.
  • the improvement in fixing is due to the relief that makes the usual smooth surface of the balloon “rough”. The stent adheres better to this rough surface.
  • the stent is first attached around the balloon and then the outside surface is provided with the relief structure.
  • a more flexible stent fixing system is obtained because at least the balloon material near the stent, both distally and proximally, is provided with a profile.
  • the stent placing system has obtained a smaller profile compared with known stent placing systems.
  • the relief structure is preferably produced on the application of heat to the surface of the balloon in order to deform the elastic material of the balloon.
  • the relief structure is also preferably produced on the surface of the balloon by applying a high pressure to the inside of the balloon.
  • the relief structure is produced on the surface of the balloon by winding a wire around the balloon in the form of a helix.
  • the relief structure is produced on the surface of the balloon by taking up the balloon in a counter-pressure body that has the relief structure.
  • FIG. 1A is a side view of a form of a balloon catheter in an uninflated state
  • FIG. 1B is a side view of the catheter in FIG. 1A in an inflated state
  • FIG. 2A is a side view of a second embodiment of a balloon catheter during the execution of the method according to the invention.
  • FIG. 2B is a side view of the final product of FIG. 2A.
  • a balloon catheter according to the invention comprises a catheter tube 1 , an inflatable balloon 2 , which at its ends 3 is attached to the catheter tube 1 , and a stent 6 attached around the balloon 2 .
  • the stent 6 extends partly along the length of the balloon 2 such that with the catheter, both distally and proximally next to the stent 6 , balloon material lies freely.
  • FIG. 1A In an uninflated state (FIG. 1A), the outside surface of the balloon 2 has a relief structure 4 that in the inflated state has virtually or completely disappeared (FIG. 1B).
  • the relief structure 4 gives the distal end of the catheter its required flexibility.
  • the relief structure 4 consists of two grooves 5 , which extend helically from one end 3 to the other end 3 of the balloon 2 and cross each other.
  • the uninflated balloon 2 has thereby obtained a padded relief surface.
  • Other relief structures are of course possible, provided that the relief, structure on the catheter creates the necessary flexibility in a direction transverse to the longitudinal direction of the balloon.
  • One way of obtaining the relief structure as shown in the drawings is by winding a wire helically around the balloon 2 .
  • This wire may, for example, be nylon wire or wire made of a different material that contracts somewhat on heating.
  • a sleeve is pulled over the balloon.
  • the balloon is heated in such a way that in an uninflated state the balloon obtains a relief structure that on dilating of the balloon at the dilatation site in the vessel or lumen will virtually or completely disappear.
  • the sleeve is then removed and the balloon catheter can be inserted into a vessel or lumen.
  • the method according to the invention can be carried out in two ways.
  • the profile is first applied to the balloon by winding this around with wire and heating it under internal pressure, and then the stent is placed on the balloon. This results in improved flexibility and maneuverability of the distal part of the catheter. Better fixing of the stent on the “rough”, profiled surface of the balloon is also achieved.
  • a stent is first placed on the balloon and then the complete distal part of the catheter, namely the balloon including the stent that has been placed in position, is wound around with wire, preferably nylon wire. Then the whole assembly is heated at a certain internal pressure. Winding produces a helical profile in the balloon material next to the stent.
  • first filler material 8 is placed next to the stent, over which wire is then also wound (see FIG. 2A). In the end this results in a small increase 7 in the balloon material next to the stent 6 (see FIG. 2B), into which the ends of the stent 6 can be pressed. As a result the ends of the stent 6 are better protected if the stent placing system is passed in a curved trajectory.
  • the balloon may be placed in a mould, which is provided with the relief pattern required, in order for it to obtain, under raised pressure and temperature, the relief structure required.
  • the balloon Before the balloon is provided with its relief structure, preferably it is folded in the usual way in order to reduce its profile. By applying the relief structure, the profile will be reduced as an additional, advantageous effect.
  • the balloon catheter may be used not only in cardiological but also radiological interventions.

Abstract

The invention relates to a balloon catheter comprising a catheter tube, an inflatable balloon, the ends of which are attached to the catheter tube, and a stent attached around the balloon. The stent extends at least partly along the length of the balloon. In an uninflated state, at least the outside surface of the balloon not covered by the stent is provided with a relief structure which is substantially disappeared in an inflated state of the balloon. The invention also relates to a method for manufacturing such a balloon catheter.

Description

    TECHNICAL FIELD
  • The present invention relates to a balloon catheter comprising a catheter tube, an inflatable balloon which at its ends is attached to the catheter tube and a stent attached around the balloon, wherein the stent extends at least in part along the length of the balloon. The invention further relates to a method of manufacturing a balloon catheter. [0001]
  • BACKGROUND INFORMATION
  • Balloon catheters of this type are generally known and are used for dilating vessels and lumina and for placing the stent in the dilated vessel or lumen. In order to pass the balloon catheter easily and safely through the vessels and lumina and to position it at the required place for dilatation, it is important that the balloon catheter has a small profile (outer diameter) and is sufficiently flexible. [0002]
  • The object of the invention is therefore to provide an improved balloon catheter. [0003]
  • BRIEF SUMMARY OF THE INVENTION
  • The balloon catheter according to the invention is characterized in that, in an uninflated state, at least the outside surface of the balloon that is not covered by the stent is provided with a relief structure which in an inflated state of the balloon is substantially disappeared. [0004]
  • Tests have shown that with a relief structure on the outside surface of the balloon a catheter is obtained that is more flexible than a standard balloon catheter. The balloon catheter according to the invention can therefore be passed more easily and more safely through vessels and lumina to the point of dilatation. Because of its flexibility, the catheter will be able to adapt better to a bend in a vessel or a lumen, thus reducing the risk of damage to the vessel or lumen. [0005]
  • The required relief structure may have different embodiments, but preferably comprises at least one groove that extends at least transversely in the longitudinal direction of the balloon in order to give the catheter the required flexibility in a direction transverse to the longitudinal direction thereof. [0006]
  • The groove preferably extends at a predetermined angle with respect to the longitudinal direction of the balloon. According to a preferred embodiment, the groove extends helically from one end to the other end of the balloon, over the outside surface thereof. [0007]
  • According to another embodiment, the relief structure comprises two or more grooves that extend helically from one end to the other end of the balloon, crossing each other. Tests have shown that with such a relief structure a very flexible balloon catheter is obtained which also has a relatively low profile. [0008]
  • The invention also relates to a method for producing a balloon catheter comprising attaching the ends of an inflatable balloon to a catheter tube and placing a stent around the balloon, whereby according to the invention at least the outside surface of the balloon not covered by the stent is provided with a relief structure. [0009]
  • According to a first embodiment, the outside surface of the balloon is first provided with the relief structure and then the stent is attached around the balloon. An additional advantage of this embodiment is that a better fixing of the stent to the balloon is achieved. The improvement in fixing is due to the relief that makes the usual smooth surface of the balloon “rough”. The stent adheres better to this rough surface. [0010]
  • According to a second embodiment, the stent is first attached around the balloon and then the outside surface is provided with the relief structure. A more flexible stent fixing system is obtained because at least the balloon material near the stent, both distally and proximally, is provided with a profile. Also, the stent placing system has obtained a smaller profile compared with known stent placing systems. [0011]
  • The relief structure is preferably produced on the application of heat to the surface of the balloon in order to deform the elastic material of the balloon. [0012]
  • The relief structure is also preferably produced on the surface of the balloon by applying a high pressure to the inside of the balloon. [0013]
  • According to a very inexpensive method, the relief structure is produced on the surface of the balloon by winding a wire around the balloon in the form of a helix. [0014]
  • According to another simple method, the relief structure is produced on the surface of the balloon by taking up the balloon in a counter-pressure body that has the relief structure.[0015]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • The invention is explained in more detail on the basis of the drawings attached. The drawings show: [0016]
  • FIG. 1A is a side view of a form of a balloon catheter in an uninflated state, [0017]
  • FIG. 1B is a side view of the catheter in FIG. 1A in an inflated state, [0018]
  • FIG. 2A is a side view of a second embodiment of a balloon catheter during the execution of the method according to the invention, and [0019]
  • FIG. 2B is a side view of the final product of FIG. 2A.[0020]
  • DETAILED DESCRIPTION OF THE INVENTION
  • A balloon catheter according to the invention comprises a [0021] catheter tube 1, an inflatable balloon 2, which at its ends 3 is attached to the catheter tube 1, and a stent 6 attached around the balloon 2. The stent 6 extends partly along the length of the balloon 2 such that with the catheter, both distally and proximally next to the stent 6, balloon material lies freely. In an uninflated state (FIG. 1A), the outside surface of the balloon 2 has a relief structure 4 that in the inflated state has virtually or completely disappeared (FIG. 1B). The relief structure 4 gives the distal end of the catheter its required flexibility.
  • In the embodiments shown, the [0022] relief structure 4 consists of two grooves 5, which extend helically from one end 3 to the other end 3 of the balloon 2 and cross each other. The uninflated balloon 2 has thereby obtained a padded relief surface. It is also possible to provide a relief structure with a single helically shaped groove 5 whereby the uninflated balloon 2 displays a relief surface in the form of a helix. Other relief structures are of course possible, provided that the relief, structure on the catheter creates the necessary flexibility in a direction transverse to the longitudinal direction of the balloon.
  • One way of obtaining the relief structure as shown in the drawings is by winding a wire helically around the [0023] balloon 2. This wire may, for example, be nylon wire or wire made of a different material that contracts somewhat on heating. After the wire has been wound around the balloon, a sleeve is pulled over the balloon. Subsequently, with the application of raised pressure to the inside of the balloon, the balloon is heated in such a way that in an uninflated state the balloon obtains a relief structure that on dilating of the balloon at the dilatation site in the vessel or lumen will virtually or completely disappear. The sleeve is then removed and the balloon catheter can be inserted into a vessel or lumen.
  • The method according to the invention can be carried out in two ways. In the first way, the profile is first applied to the balloon by winding this around with wire and heating it under internal pressure, and then the stent is placed on the balloon. This results in improved flexibility and maneuverability of the distal part of the catheter. Better fixing of the stent on the “rough”, profiled surface of the balloon is also achieved. In the second way, a stent is first placed on the balloon and then the complete distal part of the catheter, namely the balloon including the stent that has been placed in position, is wound around with wire, preferably nylon wire. Then the whole assembly is heated at a certain internal pressure. Winding produces a helical profile in the balloon material next to the stent. At the same time the diameter of the catheter with the stent is reduced because the nylon wire shrinks on heating. In a variation of this last method, [0024] first filler material 8 is placed next to the stent, over which wire is then also wound (see FIG. 2A). In the end this results in a small increase 7 in the balloon material next to the stent 6 (see FIG. 2B), into which the ends of the stent 6 can be pressed. As a result the ends of the stent 6 are better protected if the stent placing system is passed in a curved trajectory.
  • Instead of winding the wire, the balloon may be placed in a mould, which is provided with the relief pattern required, in order for it to obtain, under raised pressure and temperature, the relief structure required. [0025]
  • Before the balloon is provided with its relief structure, preferably it is folded in the usual way in order to reduce its profile. By applying the relief structure, the profile will be reduced as an additional, advantageous effect. [0026]
  • Note that, although it is not shown in the drawings, it is possible to provide the outside surface of the balloon with various helical grooves that cross each other. In addition to helical grooves, grooves of other shapes are also possible. [0027]
  • The balloon catheter may be used not only in cardiological but also radiological interventions. [0028]

Claims (55)

What is claimed is:
1. Balloon catheter comprising a catheter tube, an inflatable balloon having opposite ends and an outside surface, the ends of the balloon being attached to the catheter tube, and a stent attached around the balloon, wherein the stent extends at least partly along the length of the balloon, characterized in that, in an uninflated state, at least the outside surface of the balloon not covered by the stent is provided with a relief structure, which is substantially disappeared in an inflated state of the balloon.
2. Catheter according to claim 1, whereby the relief structure comprises at least one groove that extends at least transversely in the longitudinal direction of the balloon.
3. Catheter according to claim 2, whereby the groove extends at a predetermined angle with regard to the longitudinal direction of the balloon.
4. Catheter according to claim 2, whereby the groove extends helically from one end to the other end of the balloon, over the outside surface thereof.
5. Catheter according to claim 4, whereby the relief structure consists of at least two grooves that extend helically from one end to the other end of the balloon and cross each other.
6. Catheter according to claim 3, whereby the relief structure consists of at least two grooves that extend helically from one end to the other end of the balloon and cross each other.
7. Catheter according to claim 2, whereby the relief structure consists of at least two grooves that extend helically from one end to the other end of the balloon and cross each other.
8. Method for producing a balloon catheter comprising attaching opposite ends of an inflatable balloon to a catheter tube, attaching a stent around the balloon, and providing at least the outside surface of the balloon not covered by the stent with a relief structure.
9. Method according to claim 8, whereby first the outside surface of the balloon is provided with the relief structure, and then the stent is attached around the balloon.
10. Method according to claim 8, whereby first the stent is attached around the balloon, and then the outside surface of the balloon is provided with the relief structure.
11. Method according to claim 10, whereby before the outside surface of the balloon is provided with the relief structure, obliquely to the stent, padding is applied over the balloon and the stent.
12. Method according to claim 11, whereby the relief structure is applied to the surface of the balloon under the application of heat.
13. Method according to claim 10, whereby the relief structure is applied to the surface of the balloon under the application of heat.
14. Method according to claim 9, whereby the relief structure is applied to the surface of the balloon under the application of heat.
15. Method according to claim 8, whereby the relief structure is applied to the surface of the balloon under the application of heat.
16. Method according to claim 15, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
17. Method according to claim 14, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
18. Method according to claim 13, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
19. Method according to claim 12, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
20. Method according to claim 11, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
21. Method according to claim 10, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
22. Method according to claim 9, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
23. Method according to claim 8, whereby the relief structure is applied to the surface of the balloon under the application of raised pressure to the inside of the balloon.
24. Method according to claim 23, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
25. Method according to claim 22, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
26. Method according to claim 21, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
27. Method according to claim 20, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
28. Method according to claim 19, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
29. Method according to claim 18, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
30. Method according to claim 17, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
31. Method according to claim 16, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
32. Method according to claim 15, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
33. Method according to claim 14, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
34. Method according to claim 13, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
35. Method according to claim 12, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
36. Method according to claim 11, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
37. Method according to claim 10, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
38. Method according to claim 9, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
39. Method according to claim 8, whereby the relief structure is applied to the surface of the balloon by winding a wire helically around the balloon.
40. Method according to claim 23, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
41. Method according to claim 22, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
42. Method according to claim 21, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
43. Method according to claim 20, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
44. Method according to claim 19, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
45. Method according to claim 18, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
46. Method according to claim 17, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
47. Method according to claim 16, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
48. Method according to claim 15, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
49. Method according to claim 14, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
50. Method according to claim 13, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
51. Method according to claim 12, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
52. Method according to claim 11, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
53. Method according to claim 10, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
54. Method according to claim 9, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
55. Method according to claim 8, whereby the relief structure is applied to the surface of the balloon by taking up the balloon in a counter-pressure body provided with the relief structure.
US10/140,479 2001-05-08 2002-05-07 Balloon catheter with stent and method for manufacturing it Abandoned US20030014100A1 (en)

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US10/290,603 US20030125761A1 (en) 2001-05-08 2002-11-08 Balloon catheter
US11/555,466 US8257418B2 (en) 2001-05-08 2006-11-01 Balloon catheter with stent and method for manufacturing it
US13/600,342 US8784470B2 (en) 2001-05-08 2012-08-31 Balloon catheter with stent and method for manufacturing it
US14/310,175 US9993359B2 (en) 2001-05-08 2014-06-20 Balloon catheter with stent and method for manufacturing it
US15/952,576 US20180228631A1 (en) 2001-05-08 2018-04-13 Balloon catheter with stent and method for manufacturing it

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NL1018881A NL1018881C2 (en) 2001-05-08 2001-09-04 Balloon catheter for dilating vessels and lumina comprise inflatable balloon with ends attached to it's catheter tube
NL1018881 2001-09-04

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US13/600,342 Expired - Fee Related US8784470B2 (en) 2001-05-08 2012-08-31 Balloon catheter with stent and method for manufacturing it
US14/310,175 Expired - Fee Related US9993359B2 (en) 2001-05-08 2014-06-20 Balloon catheter with stent and method for manufacturing it
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US14/310,175 Expired - Fee Related US9993359B2 (en) 2001-05-08 2014-06-20 Balloon catheter with stent and method for manufacturing it
US15/952,576 Abandoned US20180228631A1 (en) 2001-05-08 2018-04-13 Balloon catheter with stent and method for manufacturing it

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US20070112408A1 (en) 2007-05-17
US8257418B2 (en) 2012-09-04
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US20120330400A1 (en) 2012-12-27
US20180228631A1 (en) 2018-08-16
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US20140303707A1 (en) 2014-10-09
US9993359B2 (en) 2018-06-12
US8784470B2 (en) 2014-07-22
ATE454184T1 (en) 2010-01-15
EP1270040A1 (en) 2003-01-02

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