US20030107487A1 - Method and device for measuring physiological parameters at the wrist - Google Patents
Method and device for measuring physiological parameters at the wrist Download PDFInfo
- Publication number
- US20030107487A1 US20030107487A1 US10/006,357 US635701A US2003107487A1 US 20030107487 A1 US20030107487 A1 US 20030107487A1 US 635701 A US635701 A US 635701A US 2003107487 A1 US2003107487 A1 US 2003107487A1
- Authority
- US
- United States
- Prior art keywords
- physiological parameter
- sensor
- user
- wrist
- gateway
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
-
- G—PHYSICS
- G08—SIGNALLING
- G08B—SIGNALLING OR CALLING SYSTEMS; ORDER TELEGRAPHS; ALARM SYSTEMS
- G08B21/00—Alarms responsive to a single specified undesired or abnormal condition and not otherwise provided for
- G08B21/02—Alarms for ensuring the safety of persons
- G08B21/04—Alarms for ensuring the safety of persons responsive to non-activity, e.g. of elderly persons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0204—Operational features of power management
- A61B2560/0209—Operational features of power management adapted for power saving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0266—Operational features for monitoring or limiting apparatus function
- A61B2560/0271—Operational features for monitoring or limiting apparatus function using a remote monitoring unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02438—Detecting, measuring or recording pulse rate or heart rate with portable devices, e.g. worn by the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/903—Radio telemetry
Definitions
- the present invention is of a method and device for measuring at least one physiological parameter of a subject at the wrist, preferably for extracting clinically useful information thereof. More specifically, the present invention is of a device which may be worn at the wrist of the subject with a strap or other fastening article, and which may then be used to monitor the subject through measurement of the physiological parameter.
- non-invasive monitoring of a human subject could be very useful as part of the overall health maintenance of the human subject, and could be used in order to detect a deterioration in the physiological condition of the subject before a concomitant deterioration in the health of the subject becomes noticeable.
- adverse physiological conditions which could be detected with regular non-invasive monitoring include but are not limited to excessive weight gain or less; arrhythmia and other heart conditions; incipient diabetes in the form of improper glucose metabolism; and loss of lung capacity or other problems with respiration.
- Heart rate and blood pressure are important factors in determining the state of a person's health and the physical condition of a person's body in response to physical or emotional stress. Periodic monitoring of these physical parameters is particularly important for individuals having cardiac disease and/or lowered cardiac functioning, or high blood pressure. However, physically healthy individuals may also wish to periodically monitor their heart rate and blood pressure in stressful situations, for example when engaging in strenuous exercise.
- the equipment In order to support regular monitoring of human subjects in their normal environment, such as in the home and at the office for example, the equipment must be non-invasive and easy to use. The equipment would then be able to monitor at least one physiological parameter of the user, without requiring the user to perform any complicated actions and/or to operate complex devices. Indeed, it would be highly preferred for the equipment to be incorporated as part of the regular daily living routine of the subject, since the requirement for any additional or special actions on the part of human subject is likely to result in decreased compliance. In addition, the equipment should be robust yet inexpensive.
- One example of such a device incorporates a wristband to attach a physiological sensor to the wrist of the subject.
- a wristband device to attach a physiological sensor to the wrist of the subject.
- a number of different types of such wristband devices are available, most of which are intended to be used as stand-alone devices to provide information about the subject's own physical condition, mainly for heart rate and blood pressure.
- Most of these devices obtain such measurements by using an inflating cuff, which is bulky and awkward for the subject.
- Wrist-mounted heart rate monitors are known to the art and have been disclosed, for example, in the patent to Orr et al, U.S. Pat. No. 3,807,388, wherein the duration of a heart beat is measured by counting electrical pulses recurring at a known frequency. The duration of the heartbeat is then related to a particular average heart beat rate.
- the disclosed measurement system does not directly measure the heart rate and, therefore, is subject to inaccuracies of measurement due to the instability of heart beat duration over brief intervals of time.
- a blood pressure measuring device is disclosed in the patent to Petzke et al, U.S. Pat. No. 3,926,179, in which a probe is applied adjacent to the radial artery of a wrist.
- a pressure-sensitive transducer on the probe generates electrical signals corresponding to the blood pressure pulses of the radial artery.
- the electrical pulses are applied to analog circuitry that generates a systolic signal corresponding to the integrated voltage at the peak of the electrical pulse signal and a diastolic signal corresponding to the voltage at the low point of the pulse signal.
- the analog device of Petzke et al requires a substantial amount of power to operate and, therefore, is not suitable for use in a small, compact stand-alone device for being worn on the wrist.
- a blood pressure and a heart rate measuring wrist watch is also disclosed in the patent to Broadwater, U.S. Pat. No. 4,331,154, in which a digital watch is employed to measure systolic and diastolic blood pressure as well as heart rate.
- the band of the watch supports a piezoelectric transducer that is held in contact with the wrist adjacent to the radial artery when a switch on the band is activated.
- the absolute values required for this method to evaluate blood pressure cause the device to be subject to inaccurate readings, since the tissues of the hand and wrist may be expected to expand and contract according to such factors as the time of day, and the condition of the external environment such as the atmospheric pressure. Such expansion or contraction may cause different degrees of tension on the wrist-mounted device, which is therefore not suitable for use without daily calibrations.
- Other wrist-mounted devices are for wireless panic alarm systems, mainly for elderly people who live alone. These devices are usually shaped as a wristband or a pendant. Whenever the user becomes distressed, the user presses a panic button located on the device. The device then sends a digitally coded wireless message to a gateway device located nearby, usually in the same room, by using a unidirectional wireless data communication link. The gateway device then contacts a manually operated contact center, for example with a land based or cellular telephone connection. A particular identifier for the user is usually sent first, after which the human operator is allowed to talk to the user through a speaker and to listen through a sensitive microphone located within the gateway.
- none of the above systems contains any physiological measurement device within, in order to learn about the current physiological status of the user.
- the background art does not teach or suggest a device which can conveniently, non-intrusively and autonomously measure one or more physiological parameters, in order to extract medical information such as heart rate, breathing rate and blood pressure, and which may be worn on the wrist of the user.
- the background art also does not teach or suggest such a wrist-mounted device which can measure such parameters and then send the information to a contact center or other location containing medical personnel.
- the background art also does not teach or suggest such a wrist-mounted device which is compact, non-invasive, and light.
- the present invention overcomes these deficiencies of the background art by providing a wrist-mounted device for measuring at least one physiological parameter of the user.
- the present invention enables such a measurement to preferably be transformed into medical information about the user, and/or displays the results on a LCD display.
- physiological parameter refers to the signal which is received from the sensor
- medical information refers to the information which may be extracted or otherwise obtained by analyzing this signal and/or a combination of signals.
- Such information may then optionally be sent to medical personnel (for example at a contact monitoring center) and/or to a remote server, through a gateway device.
- the gateway device preferably communicates with the wrist-mounted device of the present invention through a wireless communication channel.
- the present invention has the option to display the medical information to the user on a local LCD display, such that the user is optionally and preferably able to read the result locally.
- Examples of medical information which may be extracted from the measured physiological parameter or parameters include, but are not limited to: heart rate; variability in heart rate; breathing rate; arrhythmia of the heart (if any), as well as the general rhythm and functioning of the heart; blood pressure; presence of abnormal body movements such as convulsions for example; body position; general body movements; body temperature; presence and level of sweat; oxygen pressure in the blood; and glucose levels in the blood.
- the present invention also features an alarm signal for being transmitted through the gateway device in order to indicate an emergency or otherwise dangerous situation for the user.
- the alarm signal may optionally be transmitted according to a manual action of the user, such as pressing a “panic button” for example.
- the gateway Upon receipt of the manually activated alarm signal, the gateway would preferably initiate immediately a call to a human operated call center. Then the device would preferably automatically collect one or more current measurements of physiological parameters of the user. These measurements may be sent directly to the gateway, or alternatively may be analyzed in order to compute the medical information of the user before sending the results to the gateway. The human operator would then preferably be able to assess the user's medical condition from the received information.
- the alarm signal is transmitted automatically upon measurement of one or more physiological parameters of the user, preferably even if the user is unable to press the panic button.
- the alarm signal may be given to the user, additionally or alternatively, for example by sounding an audible alarm, more preferably from the wrist-mounted device itself.
- the device of the present invention also monitors, at least periodically but more preferably continuously, one or more physiological parameters of the user. Continuous monitoring would more easily enable the device to transmit the alarm signal if one or more physiological parameters are determined to be above predefined criteria, which may represent such medical information as unstable or excessive heart rate, or very high or low blood pressure.
- the wrist-mounted device features one or more sensors attached to a wristband or other fastening article.
- the sensor(s) are preferably connected to a microprocessor, optionally by a wire but alternatively through a wireless connection.
- the microprocessor may optionally also be located within the wristband, or otherwise attached to the wristband.
- the sensor(s) preferably support automatic collection of the measurement of the at least one physiological parameter; more preferably, the microprocessor is able to execute one or more instructions for extracting medical information about the user from such measurement(s).
- the microprocessor more preferably operates a software program to process and analyze the data which is collected, in order to compute medical information.
- the extracted information optionally also with the raw data, is then preferably transferred to the previously described gateway device.
- the gateway device then preferably relays such information to a remote server, which more preferably is able to provide such information to medical personnel, for example as part of a contact center. Therefore, continuous monitoring of the medical information and/or physiological parameters of the user may optionally and more preferably be made, enabling better medical care for the user.
- a device for measuring at least one physiological parameter of a subject comprising: (a) a fastening article for being fastened to a wrist of the user; (b) a sensor for measuring at least one physiological function of the user, the sensor being in contact with at least a portion of the wrist and the sensor being attached to the fastening article; and (c) a processor for receiving a signal from the sensor and for converting at least one measurement to form the at least one physiological parameter.
- the data may be stored on a non-volatile memory for being downloaded later by the user or by an operator.
- a system for measuring at least one physiological parameter of a subject comprising: (a) a device for measuring the at least one physiological parameter, comprising: (i) a fastening article for being fastened to a wrist of the user; (ii) a sensor for measuring at least one physiological parameter of the user, the sensor being in contact with at least a portion of the wrist and the sensor being attached to the fastening article; (iii) a communication unit for at least transmitting data; and (b) a gateway device for receiving the transmitted data for being monitored.
- a method for monitoring a physiological parameter of a user comprising: providing a device for monitoring the physiological parameter, the device being attached to at least a portion of the user at a pulse point of the user; monitoring the physiological parameter through the pulse point; and if a level of the physiological parameter of the user is outside of an expected range, transmitting an alarm.
- a device for measuring at least one physiological parameter of a subject comprising: (a) a fastening article for being fastened to a wrist of the user; (b) a piezoceramic sensor for measuring at least one physiological parameter of the user at a pulse point of the wrist and the sensor being attached to the fastening article; and (c) a processor for receiving a signal from the sensor and for converting the at least one measurement to form medical information.
- microprocessor includes, but is not limited to, general-purpose microprocessor, a DSP, a micro-controller or a special ASIC designed for that purpose.
- the method of the present invention could be described as a process for being performed by a data processor, and as such could optionally be implemented as software, hardware or firmware, or a combination thereof.
- a software application could be written in substantially any suitable programming language, which could easily be selected by one of ordinary skill in the art.
- the programming language chosen should be compatible with the computational device (computer hardware and operating system) according to which the software application is executed. Examples of suitable programming languages include, but are not limited to, Visual Basic, Assembler, Visual C, standard C, C++ and Java.
- FIG. 1 is a schematic block diagram of a system according to the present invention.
- FIG. 2 shows an exploded view of the device
- FIG. 3 describes a general state flow diagram
- FIG. 4 describes a bi-directional message format between the device and the gateway.
- the present invention is of a wrist-mounted device for measuring at least one physiological parameter of the user.
- the present invention enables such a measurement to preferably be transformed into medical information about the user. Such information may then optionally be sent to medical personnel (for example at a contact monitoring center) and/or to a remote server, through a gateway device.
- the gateway device preferably communicates with the wrist-mounted device of the present invention through a wireless communication channel.
- Examples of medical information which may be extracted from the measured physiological parameter or parameters include, but are not limited to: heart rate; variability in heart rate; breathing rate; arrhythmia of the heart (if any), as well as the general rhythm and functioning of the heart; blood pressure; presence of abnormal body movements such as convulsions for example; body position; general body movements; body temperature; presence and level of sweat; oxygen pressure in the blood; and glucose levels in the blood.
- the present invention also features an alarm signal for being transmitted through the gateway device in order to indicate an emergency or otherwise dangerous situation for the user.
- the alarm signal may optionally be transmitted according to a manual action of the user, such as pressing a “panic button” for example.
- the alarm signal is transmitted automatically upon measurement of the one or more physiological parameters of the user, preferably even if the user is unable to press the panic button.
- the alarm signal may be given to the user, additionally or alternatively, for example by sounding an audible alarm, more preferably from the wrist-mounted device itself.
- the gateway Upon receipt of the manually/automatically activated alarm signal, the gateway would preferably initiate immediately a call to a human operated call center. Then the device would preferably automatically collect one or more current physiological measurements of the user. These measurements may be sent directly to the gateway, or alternatively may be analyzed in order to compute the medical parameters of the user before sending the results to the gateway. The human operator would then preferably be able to assess the user's medical condition from the received information.
- the device of the present invention may also monitor, at least periodically but more preferably continuously, the value or condition of one or more physiological parameters of the user. Continuous monitoring would more easily enable the device to transmit the alarm signal if measurements of one or more physiological parameters are collected and analyzed by the microprocessor to form medical information, which then could be determined to be above predefined criteria, such as unstable heart rate, or very high or low blood pressure, for example.
- the wrist-mounted device features one or more sensors attached to a wristband or other fastening article.
- the sensor(s) are preferably connected to a microprocessor, optionally by a wire but alternatively through a wireless connection.
- the microprocessor may optionally also be located within the wristband, or otherwise attached to the wristband.
- the sensor(s) preferably support automatic collection of at least one physiological measurement; more preferably, the microprocessor is able to execute one or more instructions for extracting clinically useful information about the user from such measurement(s).
- the microprocessor more preferably operates a software program to process and analyze the data which is collected, in order to compute medical information.
- the extracted medical information optionally also with the raw data, is then preferably transferred to the previously described gateway device.
- the gateway device then preferably relays such information to a remote server, which more preferably is able to provide such information to medical personnel, for example as part of a contact center. Therefore, continuous monitoring of the physiological parameters of the user may optionally and more preferably be made, enabling better medical care for the user.
- a general, non-limiting example of suitable formulae for measuring the heart rate and/or other heart-related physiological parameters of a subject who is wearing the device according to the present invention may be found in the article “Cuff-less Continuous Monitoring of Beat-To-Beat Blood Pressure Using Sensor Fusion”, by Boo-Ho Yang, Yi Zhang and H. Harry Asada—IEEE (also available through http://web.mit.edu/zyi/www/pdf/IEEETrans2000.pdt as of Dec. 9, 2001), hereby incorporated by reference as if fully set forth herein, where systolic and diastolic blood pressure are calculated using the pulse pressure shape per heartbeat.
- the disclosure does not describe a device which has the functionality according to the present invention, but the disclosed method is generally useful for determining blood pressure from an external measurement of pressure from the pulse through the skin of the subject.
- FIG. 1 is a schematic block diagram of a system according to the present invention.
- a system 1 features a wearable device 101 to be worn by a user, preferably as a wrist-mounted device, for example by being attached with a wristband or other fastening article to the wrist of the user.
- Device 101 features at least one physiological sensor 102 for measuring at least one physiological parameter of the user. The function of an exemplary sensor 102 is described in greater detail below.
- the device 101 also preferably features a vibration sensor 123 , preferably a piezoceramic sensor, which is not in direct contact with the skin of the user. Sensor 123 measures the movement of the wrist. The output of sensor 123 can be used by a processing unit 103 to capture the movement of the wrist and to recover some noise received by sensor 102 which is caused by such movement.
- a vibration sensor 123 preferably a piezoceramic sensor, which is not in direct contact with the skin of the user.
- Sensor 123 measures the movement of the wrist.
- the output of sensor 123 can be used by a processing unit 103 to capture the movement of the wrist and to recover some noise received by sensor 102 which is caused by such movement.
- processing unit 103 In order to support processing of the measured physiological parameter or parameters, processing unit 103 more preferably includes internal RAM and non-volatile program memory (not shown). Also more preferably, processing unit 103 includes an extended data memory 105 located externally to processing unit 103 . Processing unit 103 preferably executes at least one instruction for processing the data obtained by sensor 102 .
- Examples of such processing units 103 include but are not limited to PIC18LC452 by Microchip Technology Inc., which contains 10 channels of 10 bit A/D converters, a 1.5K bytes of internal RAM and 32K Bytes of non-volatile program memory.
- Extended memory component 105 is preferably an electrically erasable non-volatile external memory component.
- Examples of such a memory component include but are not limited to FM24CL64-S (Ramtron, USA), with 64 Kbit of fast access read/write serial memory for storing temporary data related to the sampled physiological parameter.
- Device 101 optionally and preferably features a real time clock 117 in order to provide an accurate time and date for each measurement, as device 101 can optionally store a few measurements before transmitting such data and/or information to a gateway device 110 , as described in greater detail below. Stored data and/or information may also optionally be used for such applications as reminding the subject to take medication, perform a medical diagnostic measurement, and so forth.
- An A/D converter 109 with multiple inputs is also optionally and preferably present if sensor 102 is an analog sensor, in order to convert the analog signal to a digital signal.
- Device 101 preferably features an internal communication unit 104 , for at least unidirectional, but more preferably bi-directional, communication with gateway device 110 .
- Gateway device 110 also preferably features a communication unit 107 .
- Communication unit 104 may optionally communicate with communication unit 107 through a wire or alternatively through a wireless communication link 121 .
- gateway device 110 is located relatively close to the user and hence to device 101 , for example by being located in the same building. As a non-limiting example, gateway device 110 could optionally be installed in the home of the user.
- Gateway device 110 also optionally and preferably features a controller 108 for controlling functions of gateway device 110 , such as communication with device 101 for example.
- Gateway device 110 preferably communicates with a remote server 114 through a data link 120 , which could optionally be a direct dial-up modem connection with DTMF coding or TCP/IP using regular LAN or dial-up modem connection to an ISP, for example.
- data link 120 may optionally be a wired or wireless link, for example through a cellular telephone and/or land-based telephone system, or a combination thereof.
- Remote server 114 optionally and more preferably features a system administrator 112 , which may be a person (for manual operation) or a software program (for automatic operation), or a combination thereof. Remote server 114 also preferably features a database 113 for storing data received from gateway device 110 .
- Device 101 may also feature a manually operated panic alarm button 116 to be manually activated by the user, for example if the user is in distress.
- Device 101 may also optionally feature a LED display 118 , for example in order to indicate of alert activation or a low battery level.
- Physiological sensor 102 is preferably part of a sensor assembly. Without wishing to be limited in any way, the following discussion centers around such a physiological sensor 102 which contains a piezoceramic transducer for generating an electrical signal, having an amplitude corresponding to the magnitude of applied pressure. Therefore, if at least a portion of the transducer is located adjacent to, and in physical contact with, an area of the wrist where blood pressure pulses may be detected, the transducer generates electrical pressure pulses corresponding to the detected blood pressure pulses. Each of the electrical pressure pulses preferably defines a maximum voltage over a systolic interval and a minimum voltage over a diastolic interval.
- piezoceramic sensor is used as a pressure transducer according to a preferred embodiment of the invention, it should be appreciated that other transducers known to the art may be employed without departing from the spirit of the invention. Examples of such sensors include but are not limited to piezoelectric transducers, resistive strain gauges and pressure sensor made of fiber-optic techniques.
- the piezoceramic transducer is desirable for the present invention since the transducer measures the direct effect of the pressure exerted within the radial artery, while other transducers, for example resistive strain gauges, measure secondary effects such as the strain forces that are applied at the surface of the skin due to the expansion of the radial artery. Piezoceramic transducers are also cheaper than piezoelectric transducers but still produce a high-quality signal.
- the analog output of sensor 102 is first preferably treated by an analog front-end 119 which more preferably contains an analog filter (not shown).
- this analog filter preferably has a cutoff of about 20 Hz, a linear phase response, a flat amplitude response up to 10 Hz and an amplification of about 3 for acquiring the full spectrum of a typical blood pressure pulse.
- the filtered signal then enters A/D converter 109 .
- Processing unit 103 preferably controls the operation of A/D converter 109 .
- A/D converter 109 starts sampling the filtered analog signal of sensor 102 from analog front-end 119 , preferably at a rate controlled by processing unit 103 . This rate is optionally and more preferably 80 samples per second as to over sample the data by a factor of 4 to maintain a good quality sampled signal.
- A/D converter 109 preferably transfers the analog data into a digital coded word, preferably at resolution of 10 bits per sample.
- Processing unit 103 preferably operates a software program for examining the validity of the sampled data, in order to determine whether the data contains some indications of legitimate physiological data (such as of a blood pressure pulse of an artery) or alternatively whether the data contains only noise or poor readings.
- A/D converter 109 preferably starts sampling the signal again in order to obtain data for measurement. This process preferably continues until the software determines that sufficient valid data has been collected or after a few successive rejections (usually after 3 times).
- the software program preferably performs an algorithm for calculating some medical parameters from the sampled data, such as the calculation of systolic and diastolic blood pressure using a method as disclosed in the previously described U.S. Pat. No. 4,418,700, which is hereby incorporated by reference as if fully set forth herein.
- the calculated parameters are then preferably stored in memory 105 .
- the data stored in memory 105 is preferably transmitted to gateway device 110 periodically, or alternatively or additionally after manual operation of panic button 116 .
- the calculated parameters are also optionally and preferably displayed on a local LCD display ( 124 ), so the user can view the last medical results locally.
- data for all medical parameters that are sent to remote server ( 114 ) are sent according to a security protocol for maintaining the privacy of the user.
- the software program preferably performs another algorithm for generating an alert if the medical parameters have values beyond or otherwise outside of the normal expected values.
- device 101 preferably features a two-way communication link as shown for link 121 , for establishing more reliable communication with gateway device 110 .
- Examples of communication units 104 , 107 include but are not limited to a nRF401 UHF transceiver (Nordic), which operates in the universal ISM band (433.92 Mhz), an infrared transceiver, and a “Bluetooth” protocol enabled-transceiver operating bi-directionally in the 2.4 GHz band.
- Device 101 preferably has its own unique identifier, stored in non-volatile data storage, more preferably in memory 105 . Each time device 101 sends a wireless message to gateway device 110 , device 101 also preferably sends the unique identifier to gateway device 110 , although optionally the identifier may be sent only periodically, for example once per day. Gateway device 110 also preferably sends a message to a particular device 101 by including the device identifier in the message, thereby specifying which such device should receive the message.
- device 101 preferably has its own real time clock 117 .
- real time clock 117 is preferably used to provide a time tag for each set of results. This time tag is very important for continuous monitoring of the user for long periods of time. By examining the data recorded over of the user for long period of time, a change or alteration in the health condition of the user may be detected.
- Real time clock 117 may optionally be implemented by separate hardware such as RTC8564 (EPSON, US) for example, or alternatively by a software program for operation by processing unit 103 .
- Device 101 also preferably features a power source such as a battery 106 , which powers device 101 .
- a power source such as a battery 106
- suitable batteries include but are not limited to the silver oxide coin battery model 386 (Panasonic, Japan) having 150 mAh in capacity with a pulse burst of 75 mA for a short period of time (about 5 sec for each pulse).
- Battery 106 optionally and preferably contains enough energy to power the device for more than one year of operation without being replaced.
- FIG. 2 shows an exploded view of the exemplary device according to FIG. 1.
- the device features sensor 102 , shown with the preferred but exemplary implementation of a piezoceramic sensor as previously described.
- the device also optionally and preferably features battery 106 , and a push button 316 (for optional implementation of the alarm button of the device of FIG. 1).
- Battery 106 may optionally be replaced with a plurality of smaller batteries (not shown).
- the device preferably features a processor 314 (which may optionally be similar or identical to the processing unit of the device of FIG. 1).
- sensor 102 is in physical contact with an anvil 300 .
- Anvil 300 preferably features a protrusion 302 which presses against the skin of the wrist of the subject (not shown), more preferably at a pulse point. Protrusion 302 therefore receives pressure with each pulse of the blood of the subject. This pressure is transduced through anvil 300 to sensor 102 , which then emits voltage to form a signal, preferably according to a linear output.
- processor 314 which preferably extracts medical information from the measurement of the physiological parameter.
- Processor 314 optionally and preferably features a crystal oscillator 314 , for stabilizing the internal clock of processor 314 .
- Processor 314 is also preferably in contact with the real time clock of the device (not shown). Also not shown are the extended memory, transceiver (communication unit), A/D converter and analog front end of the device.
- Processor 314 , oscillator 312 and push button 316 are all preferably mounted on a PCB board 308 .
- PCB board 308 is then preferably sandwiched between battery 106 and a device cover 304 .
- Device cover 304 preferably features a soft cover, which may be rubber for example, for enabling the user to locate and depress the alarm button through push button 316 .
- An o-ring 310 is preferably used for waterproof sealing between the upper and the bottom parts of the device.
- Anvil 300 then is held between sensor 102 and the skin of the user (not shown), for example by being affixed to sensor 102 with an adhesive substance.
- sensor 102 and anvil 300 could optionally be located in the wristband for affixing the device to the wrist of the user (not shown).
- FIG. 3 is a flow chart of the operation of the device.
- the software preferably makes some initializations using default values.
- the software preferably triggers a watchdog function shown as a “Watchdog” process, and then enters a sleeping mode for saving battery life, shown as a “Sleep” process.
- the device is preferably “woken up” according to one of three triggers.
- the device is preferably woken up when the user presses a panic button manually. This process is shown by the “Alarm” state.
- the device then preferably immediately starts a transmission to the gateway device, containing a distress indication and the device identifier. Then the device enters a receiving mode for a few seconds, waiting for acknowledge (ACK) from the gateway device. This process is shown as a “TX/RX” state.
- acknowledge message is not received within this period of time a repeated message is initiated. Additional transmissions are initiated, if necessary. However, if after a predefined number of repeated times an acknowledge message is not received, an error message is stored within a log and no more tries are made. More preferably an indication LED starts blinking for a few seconds, optionally with an audible alarm. Then, the process returns to the “Sleep” state.
- the process After receiving acknowledge, the process turns to “Supervise” state, where the device collects data from its sensors, preferably calculates some medical information concerning the current physiological status of the user. Then, it turns into “Tx/Rx” state, where the device transmits a message containing the identifier, and the calculated medical parameters. And if the received ACK contains no commands it returns to the “Sleep” state, otherwise it does the command and sends an ACK to the gateway. The gateway returns an ACK with another command to continue or without a command to terminate this process. After doing the last command the device returns to the “Sleep” state.
- an external real time clock signals the device to execute an automatic check. Then, the process enters “Supervise” state as discussed in the above paragraph, only that this time for saving battery life, the device initiate the “Tx/Rx” process only once for a few successive times sending all the accumulated data in one transmission. Then, the device preferably enters a “Sleep” state unless the measured parameters exceed a predefined threshold at least once, but preferably for a few successive measurements. In this case, the device initiates an automatic alarm entering the “Alarm” state, if the device has permission to do so, as previously described.
- the device When a timer for a supervise process has been running or after an alarm, the device preferably exercises an automatic check as described above, and after that initiates a transmission to the gateway device including all the data collected after the last transmission. Then the device preferably waits for acknowledge, preferably repeating the transmission again if not receiving such an acknowledge message. In the acknowledge message, a command for the device can be stored. In such a case the device performs this command and then it sends an acknowledge message to the gateway device. This process may optionally continue until an acknowledge message without a command is received, after which the device preferably returns to sleep mode.
- the device exit “Sleep” mode if of technical reasons a technician wants to change the operation software, the device enters “Boot Loader” state where a new software is loaded “on the fly” without a need to disconnect the batteries.
- FIG. 4 describes an exemplary message format for exchanging messages between the device and the gateway device. Every message preferably starts with a preamble STX byte (hex 7E), followed by a byte which contains the number of bytes in the current message, and three bytes of address, followed by a command byte and its corresponding data bytes. This is followed by two bytes of CRC and an ETX byte (hex 7B).
- the message is a variable length message with strong error detection and correction method for enhanced communication reliability.
- Each message optionally and preferably contains a low battery indication, if necessary.
- a repeated message is preferably transmitted for a predefined number of times, such as 20 times for example, after which the device preferably enters a sleeping mode if no answer is received.
- an acknowledge message is preferably returned by the gateway device and vise versa.
- This message may also contain a command for the device encoded in the CMD byte within the message. Commands could optionally include, but are not limited to, one or more of the following:
- the device may optionally contain a Battery OK/Battery Low indication for the battery situation. This signal preferably appears three months before the battery finishes, enough time to ask the user to replace the battery.
- the device sends a supervise-type message to the gateway, it preferably sends also all the medical data stored in its memory with that message.
- the gateway device Each time the gateway device sends a command back to the device, the device preferably returns an acknowledge message with a 3 bit message serial number to the gateway device, in order to fulfill a full handshake between the two. If the gateway device does not receive acknowledge from the device within a few seconds, the gateway device preferably sends its transmission message again with the same serial number. The message may even be repeated a few times, each time waiting for acknowledge. If acknowledge is not received, a logbook is updated with an error message, and more preferably an indication LED is turned on for error indication.
Abstract
A wrist-mounted device for measuring at least one physiological parameter of the user. The present invention enables such a measurement to preferably be transformed into clinically useful information about the user. Such information may then optionally be sent to medical personnel, for example at a contact and/or monitoring center, through a gateway device. The gateway device preferably communicates with the wrist-mounted device of the present invention through a wireless communication channel.
Description
- The present invention is of a method and device for measuring at least one physiological parameter of a subject at the wrist, preferably for extracting clinically useful information thereof. More specifically, the present invention is of a device which may be worn at the wrist of the subject with a strap or other fastening article, and which may then be used to monitor the subject through measurement of the physiological parameter.
- Currently, a number of different types of devices are available for monitoring human subjects in a non-invasive manner. For example, heart function can be monitored in a patient through the use of electrodes which must be attached to the skin of the patient. Although non-invasive, such equipment is nevertheless uncomfortable for the patient, who is attached to a network of cables and wired sensors. In addition, such equipment is very expensive, limiting its use to hospitals and other medical settings in which both the cost and the discomfort of the patient can be justified. Furthermore, patients may become anxious when examined by medical personnel, thereby significantly altering the normal readings for these patients.
- However, there are many different situations in which non-invasive monitoring of a human subject is desired. For example, such monitoring could be very useful as part of the overall health maintenance of the human subject, and could be used in order to detect a deterioration in the physiological condition of the subject before a concomitant deterioration in the health of the subject becomes noticeable. Examples of adverse physiological conditions which could be detected with regular non-invasive monitoring include but are not limited to excessive weight gain or less; arrhythmia and other heart conditions; incipient diabetes in the form of improper glucose metabolism; and loss of lung capacity or other problems with respiration.
- Heart rate and blood pressure are important factors in determining the state of a person's health and the physical condition of a person's body in response to physical or emotional stress. Periodic monitoring of these physical parameters is particularly important for individuals having cardiac disease and/or lowered cardiac functioning, or high blood pressure. However, physically healthy individuals may also wish to periodically monitor their heart rate and blood pressure in stressful situations, for example when engaging in strenuous exercise.
- In order to support regular monitoring of human subjects in their normal environment, such as in the home and at the office for example, the equipment must be non-invasive and easy to use. The equipment would then be able to monitor at least one physiological parameter of the user, without requiring the user to perform any complicated actions and/or to operate complex devices. Indeed, it would be highly preferred for the equipment to be incorporated as part of the regular daily living routine of the subject, since the requirement for any additional or special actions on the part of human subject is likely to result in decreased compliance. In addition, the equipment should be robust yet inexpensive.
- One example of such a device incorporates a wristband to attach a physiological sensor to the wrist of the subject. Currently, a number of different types of such wristband devices are available, most of which are intended to be used as stand-alone devices to provide information about the subject's own physical condition, mainly for heart rate and blood pressure. Most of these devices obtain such measurements by using an inflating cuff, which is bulky and awkward for the subject.
- Wrist-mounted heart rate monitors are known to the art and have been disclosed, for example, in the patent to Orr et al, U.S. Pat. No. 3,807,388, wherein the duration of a heart beat is measured by counting electrical pulses recurring at a known frequency. The duration of the heartbeat is then related to a particular average heart beat rate. However, the disclosed measurement system does not directly measure the heart rate and, therefore, is subject to inaccuracies of measurement due to the instability of heart beat duration over brief intervals of time.
- A blood pressure measuring device is disclosed in the patent to Petzke et al, U.S. Pat. No. 3,926,179, in which a probe is applied adjacent to the radial artery of a wrist. A pressure-sensitive transducer on the probe generates electrical signals corresponding to the blood pressure pulses of the radial artery. The electrical pulses are applied to analog circuitry that generates a systolic signal corresponding to the integrated voltage at the peak of the electrical pulse signal and a diastolic signal corresponding to the voltage at the low point of the pulse signal. The analog device of Petzke et al requires a substantial amount of power to operate and, therefore, is not suitable for use in a small, compact stand-alone device for being worn on the wrist.
- A blood pressure and a heart rate measuring wrist watch is also disclosed in the patent to Broadwater, U.S. Pat. No. 4,331,154, in which a digital watch is employed to measure systolic and diastolic blood pressure as well as heart rate. The band of the watch supports a piezoelectric transducer that is held in contact with the wrist adjacent to the radial artery when a switch on the band is activated. The absolute values required for this method to evaluate blood pressure cause the device to be subject to inaccurate readings, since the tissues of the hand and wrist may be expected to expand and contract according to such factors as the time of day, and the condition of the external environment such as the atmospheric pressure. Such expansion or contraction may cause different degrees of tension on the wrist-mounted device, which is therefore not suitable for use without daily calibrations.
- Other wrist-mounted devices are for wireless panic alarm systems, mainly for elderly people who live alone. These devices are usually shaped as a wristband or a pendant. Whenever the user becomes distressed, the user presses a panic button located on the device. The device then sends a digitally coded wireless message to a gateway device located nearby, usually in the same room, by using a unidirectional wireless data communication link. The gateway device then contacts a manually operated contact center, for example with a land based or cellular telephone connection. A particular identifier for the user is usually sent first, after which the human operator is allowed to talk to the user through a speaker and to listen through a sensitive microphone located within the gateway. However, none of the above systems contains any physiological measurement device within, in order to learn about the current physiological status of the user.
- In such a situation as described above, the operator at the call center learns about the user's condition only by speaking with the user. However, this is only possible if the user is actually able to speak. High levels of background noise may also prevent the user from being heard by the microphone of the gateway device.
- The background art does not teach or suggest a device which can conveniently, non-intrusively and autonomously measure one or more physiological parameters, in order to extract medical information such as heart rate, breathing rate and blood pressure, and which may be worn on the wrist of the user. The background art also does not teach or suggest such a wrist-mounted device which can measure such parameters and then send the information to a contact center or other location containing medical personnel. The background art also does not teach or suggest such a wrist-mounted device which is compact, non-invasive, and light.
- The present invention overcomes these deficiencies of the background art by providing a wrist-mounted device for measuring at least one physiological parameter of the user. The present invention enables such a measurement to preferably be transformed into medical information about the user, and/or displays the results on a LCD display. As used herein, the term “physiological parameter” refers to the signal which is received from the sensor, while the term “medical information” refers to the information which may be extracted or otherwise obtained by analyzing this signal and/or a combination of signals. Such information may then optionally be sent to medical personnel (for example at a contact monitoring center) and/or to a remote server, through a gateway device. The gateway device preferably communicates with the wrist-mounted device of the present invention through a wireless communication channel.
- The present invention has the option to display the medical information to the user on a local LCD display, such that the user is optionally and preferably able to read the result locally.
- Examples of medical information which may be extracted from the measured physiological parameter or parameters include, but are not limited to: heart rate; variability in heart rate; breathing rate; arrhythmia of the heart (if any), as well as the general rhythm and functioning of the heart; blood pressure; presence of abnormal body movements such as convulsions for example; body position; general body movements; body temperature; presence and level of sweat; oxygen pressure in the blood; and glucose levels in the blood.
- Optionally and more preferably, the present invention also features an alarm signal for being transmitted through the gateway device in order to indicate an emergency or otherwise dangerous situation for the user. The alarm signal may optionally be transmitted according to a manual action of the user, such as pressing a “panic button” for example.
- Upon receipt of the manually activated alarm signal, the gateway would preferably initiate immediately a call to a human operated call center. Then the device would preferably automatically collect one or more current measurements of physiological parameters of the user. These measurements may be sent directly to the gateway, or alternatively may be analyzed in order to compute the medical information of the user before sending the results to the gateway. The human operator would then preferably be able to assess the user's medical condition from the received information.
- Most preferably, the alarm signal is transmitted automatically upon measurement of one or more physiological parameters of the user, preferably even if the user is unable to press the panic button. Optionally, the alarm signal may be given to the user, additionally or alternatively, for example by sounding an audible alarm, more preferably from the wrist-mounted device itself.
- The device of the present invention also monitors, at least periodically but more preferably continuously, one or more physiological parameters of the user. Continuous monitoring would more easily enable the device to transmit the alarm signal if one or more physiological parameters are determined to be above predefined criteria, which may represent such medical information as unstable or excessive heart rate, or very high or low blood pressure.
- According to preferred embodiments of the present invention, the wrist-mounted device features one or more sensors attached to a wristband or other fastening article. The sensor(s) are preferably connected to a microprocessor, optionally by a wire but alternatively through a wireless connection. The microprocessor may optionally also be located within the wristband, or otherwise attached to the wristband. The sensor(s) preferably support automatic collection of the measurement of the at least one physiological parameter; more preferably, the microprocessor is able to execute one or more instructions for extracting medical information about the user from such measurement(s).
- The microprocessor more preferably operates a software program to process and analyze the data which is collected, in order to compute medical information. The extracted information, optionally also with the raw data, is then preferably transferred to the previously described gateway device. The gateway device then preferably relays such information to a remote server, which more preferably is able to provide such information to medical personnel, for example as part of a contact center. Therefore, continuous monitoring of the medical information and/or physiological parameters of the user may optionally and more preferably be made, enabling better medical care for the user. According to the present invention there is provided a device for measuring at least one physiological parameter of a subject, comprising: (a) a fastening article for being fastened to a wrist of the user; (b) a sensor for measuring at least one physiological function of the user, the sensor being in contact with at least a portion of the wrist and the sensor being attached to the fastening article; and (c) a processor for receiving a signal from the sensor and for converting at least one measurement to form the at least one physiological parameter. Optionally and preferably, the data may be stored on a non-volatile memory for being downloaded later by the user or by an operator.
- According to another embodiment of the present invention, there is provided a system for measuring at least one physiological parameter of a subject, comprising: (a) a device for measuring the at least one physiological parameter, comprising: (i) a fastening article for being fastened to a wrist of the user; (ii) a sensor for measuring at least one physiological parameter of the user, the sensor being in contact with at least a portion of the wrist and the sensor being attached to the fastening article; (iii) a communication unit for at least transmitting data; and (b) a gateway device for receiving the transmitted data for being monitored.
- According to another embodiment of the present invention, there is provided a method for monitoring a physiological parameter of a user, comprising: providing a device for monitoring the physiological parameter, the device being attached to at least a portion of the user at a pulse point of the user; monitoring the physiological parameter through the pulse point; and if a level of the physiological parameter of the user is outside of an expected range, transmitting an alarm.
- According to still another embodiment of the present invention, there is provided a device for measuring at least one physiological parameter of a subject, comprising: (a) a fastening article for being fastened to a wrist of the user; (b) a piezoceramic sensor for measuring at least one physiological parameter of the user at a pulse point of the wrist and the sensor being attached to the fastening article; and (c) a processor for receiving a signal from the sensor and for converting the at least one measurement to form medical information.
- Hereinafter, the term “microprocessor” includes, but is not limited to, general-purpose microprocessor, a DSP, a micro-controller or a special ASIC designed for that purpose.
- The method of the present invention could be described as a process for being performed by a data processor, and as such could optionally be implemented as software, hardware or firmware, or a combination thereof. For the present invention, a software application could be written in substantially any suitable programming language, which could easily be selected by one of ordinary skill in the art. The programming language chosen should be compatible with the computational device (computer hardware and operating system) according to which the software application is executed. Examples of suitable programming languages include, but are not limited to, Visual Basic, Assembler, Visual C, standard C, C++ and Java.
- The invention is herein described, by way of example only, with reference to the accompanying drawings, wherein:
- FIG. 1 is a schematic block diagram of a system according to the present invention;
- FIG. 2 shows an exploded view of the device;
- FIG. 3 describes a general state flow diagram; and
- FIG. 4 describes a bi-directional message format between the device and the gateway.
- The present invention is of a wrist-mounted device for measuring at least one physiological parameter of the user. The present invention enables such a measurement to preferably be transformed into medical information about the user. Such information may then optionally be sent to medical personnel (for example at a contact monitoring center) and/or to a remote server, through a gateway device. The gateway device preferably communicates with the wrist-mounted device of the present invention through a wireless communication channel.
- Examples of medical information which may be extracted from the measured physiological parameter or parameters include, but are not limited to: heart rate; variability in heart rate; breathing rate; arrhythmia of the heart (if any), as well as the general rhythm and functioning of the heart; blood pressure; presence of abnormal body movements such as convulsions for example; body position; general body movements; body temperature; presence and level of sweat; oxygen pressure in the blood; and glucose levels in the blood.
- Optionally and more preferably, the present invention also features an alarm signal for being transmitted through the gateway device in order to indicate an emergency or otherwise dangerous situation for the user. The alarm signal may optionally be transmitted according to a manual action of the user, such as pressing a “panic button” for example.
- Most preferably, the alarm signal is transmitted automatically upon measurement of the one or more physiological parameters of the user, preferably even if the user is unable to press the panic button. Optionally, the alarm signal may be given to the user, additionally or alternatively, for example by sounding an audible alarm, more preferably from the wrist-mounted device itself. Upon receipt of the manually/automatically activated alarm signal, the gateway would preferably initiate immediately a call to a human operated call center. Then the device would preferably automatically collect one or more current physiological measurements of the user. These measurements may be sent directly to the gateway, or alternatively may be analyzed in order to compute the medical parameters of the user before sending the results to the gateway. The human operator would then preferably be able to assess the user's medical condition from the received information.
- The device of the present invention may also monitor, at least periodically but more preferably continuously, the value or condition of one or more physiological parameters of the user. Continuous monitoring would more easily enable the device to transmit the alarm signal if measurements of one or more physiological parameters are collected and analyzed by the microprocessor to form medical information, which then could be determined to be above predefined criteria, such as unstable heart rate, or very high or low blood pressure, for example.
- According to preferred embodiments of the present invention, the wrist-mounted device features one or more sensors attached to a wristband or other fastening article. The sensor(s) are preferably connected to a microprocessor, optionally by a wire but alternatively through a wireless connection. The microprocessor may optionally also be located within the wristband, or otherwise attached to the wristband. The sensor(s) preferably support automatic collection of at least one physiological measurement; more preferably, the microprocessor is able to execute one or more instructions for extracting clinically useful information about the user from such measurement(s).
- The microprocessor more preferably operates a software program to process and analyze the data which is collected, in order to compute medical information. The extracted medical information, optionally also with the raw data, is then preferably transferred to the previously described gateway device. The gateway device then preferably relays such information to a remote server, which more preferably is able to provide such information to medical personnel, for example as part of a contact center. Therefore, continuous monitoring of the physiological parameters of the user may optionally and more preferably be made, enabling better medical care for the user.
- A general, non-limiting example of suitable formulae for measuring the heart rate and/or other heart-related physiological parameters of a subject who is wearing the device according to the present invention may be found in the article “Cuff-less Continuous Monitoring of Beat-To-Beat Blood Pressure Using Sensor Fusion”, by Boo-Ho Yang, Yi Zhang and H. Harry Asada—IEEE (also available through http://web.mit.edu/zyi/www/pdf/IEEETrans2000.pdt as of Dec. 9, 2001), hereby incorporated by reference as if fully set forth herein, where systolic and diastolic blood pressure are calculated using the pulse pressure shape per heartbeat. The disclosure does not describe a device which has the functionality according to the present invention, but the disclosed method is generally useful for determining blood pressure from an external measurement of pressure from the pulse through the skin of the subject.
- The principles and operation of a device and method according to the present invention may be better understood with reference to the drawings and the accompanying description.
- Referring now to the drawings, FIG. 1 is a schematic block diagram of a system according to the present invention. As shown, a
system 1 features awearable device 101 to be worn by a user, preferably as a wrist-mounted device, for example by being attached with a wristband or other fastening article to the wrist of the user.Device 101 features at least onephysiological sensor 102 for measuring at least one physiological parameter of the user. The function of anexemplary sensor 102 is described in greater detail below. - The
device 101 also preferably features avibration sensor 123, preferably a piezoceramic sensor, which is not in direct contact with the skin of the user.Sensor 123 measures the movement of the wrist. The output ofsensor 123 can be used by aprocessing unit 103 to capture the movement of the wrist and to recover some noise received bysensor 102 which is caused by such movement. - In order to support processing of the measured physiological parameter or parameters, processing
unit 103 more preferably includes internal RAM and non-volatile program memory (not shown). Also more preferably, processingunit 103 includes an extendeddata memory 105 located externally toprocessing unit 103.Processing unit 103 preferably executes at least one instruction for processing the data obtained bysensor 102. - Examples of
such processing units 103 include but are not limited to PIC18LC452 by Microchip Technology Inc., which contains 10 channels of 10 bit A/D converters, a 1.5K bytes of internal RAM and 32K Bytes of non-volatile program memory. -
Extended memory component 105 is preferably an electrically erasable non-volatile external memory component. Examples of such a memory component include but are not limited to FM24CL64-S (Ramtron, USA), with 64 Kbit of fast access read/write serial memory for storing temporary data related to the sampled physiological parameter. -
Device 101 optionally and preferably features a real time clock 117 in order to provide an accurate time and date for each measurement, asdevice 101 can optionally store a few measurements before transmitting such data and/or information to agateway device 110, as described in greater detail below. Stored data and/or information may also optionally be used for such applications as reminding the subject to take medication, perform a medical diagnostic measurement, and so forth. An A/D converter 109 with multiple inputs is also optionally and preferably present ifsensor 102 is an analog sensor, in order to convert the analog signal to a digital signal. -
Device 101 preferably features an internal communication unit 104, for at least unidirectional, but more preferably bi-directional, communication withgateway device 110.Gateway device 110 also preferably features acommunication unit 107. Communication unit 104 may optionally communicate withcommunication unit 107 through a wire or alternatively through awireless communication link 121. According to preferred embodiments of the present invention,gateway device 110 is located relatively close to the user and hence todevice 101, for example by being located in the same building. As a non-limiting example,gateway device 110 could optionally be installed in the home of the user. -
Gateway device 110 also optionally and preferably features acontroller 108 for controlling functions ofgateway device 110, such as communication withdevice 101 for example. -
Gateway device 110 preferably communicates with aremote server 114 through adata link 120, which could optionally be a direct dial-up modem connection with DTMF coding or TCP/IP using regular LAN or dial-up modem connection to an ISP, for example. In any case,data link 120 may optionally be a wired or wireless link, for example through a cellular telephone and/or land-based telephone system, or a combination thereof. -
Remote server 114 optionally and more preferably features asystem administrator 112, which may be a person (for manual operation) or a software program (for automatic operation), or a combination thereof.Remote server 114 also preferably features adatabase 113 for storing data received fromgateway device 110. -
Device 101 may also feature a manually operatedpanic alarm button 116 to be manually activated by the user, for example if the user is in distress.Device 101 may also optionally feature aLED display 118, for example in order to indicate of alert activation or a low battery level. -
Physiological sensor 102 is preferably part of a sensor assembly. Without wishing to be limited in any way, the following discussion centers around such aphysiological sensor 102 which contains a piezoceramic transducer for generating an electrical signal, having an amplitude corresponding to the magnitude of applied pressure. Therefore, if at least a portion of the transducer is located adjacent to, and in physical contact with, an area of the wrist where blood pressure pulses may be detected, the transducer generates electrical pressure pulses corresponding to the detected blood pressure pulses. Each of the electrical pressure pulses preferably defines a maximum voltage over a systolic interval and a minimum voltage over a diastolic interval. - Although a piezoceramic sensor is used as a pressure transducer according to a preferred embodiment of the invention, it should be appreciated that other transducers known to the art may be employed without departing from the spirit of the invention. Examples of such sensors include but are not limited to piezoelectric transducers, resistive strain gauges and pressure sensor made of fiber-optic techniques.
- The piezoceramic transducer is desirable for the present invention since the transducer measures the direct effect of the pressure exerted within the radial artery, while other transducers, for example resistive strain gauges, measure secondary effects such as the strain forces that are applied at the surface of the skin due to the expansion of the radial artery. Piezoceramic transducers are also cheaper than piezoelectric transducers but still produce a high-quality signal.
- As shown with regard to FIG. 1, the analog output of
sensor 102 is first preferably treated by an analog front-end 119 which more preferably contains an analog filter (not shown). As a non-limiting example, this analog filter preferably has a cutoff of about 20Hz, a linear phase response, a flat amplitude response up to 10 Hz and an amplification of about 3 for acquiring the full spectrum of a typical blood pressure pulse. The filtered signal then enters A/D converter 109. -
Processing unit 103 preferably controls the operation of A/D converter 109. When a physiological measurement is initiated, A/D converter 109 starts sampling the filtered analog signal ofsensor 102 from analog front-end 119, preferably at a rate controlled by processingunit 103. This rate is optionally and more preferably 80 samples per second as to over sample the data by a factor of 4 to maintain a good quality sampled signal. A/D converter 109 preferably transfers the analog data into a digital coded word, preferably at resolution of 10 bits per sample. - Preferably about 30 seconds of data is gathered for each measurement.
Processing unit 103 preferably operates a software program for examining the validity of the sampled data, in order to determine whether the data contains some indications of legitimate physiological data (such as of a blood pressure pulse of an artery) or alternatively whether the data contains only noise or poor readings. In the second case, A/D converter 109 preferably starts sampling the signal again in order to obtain data for measurement. This process preferably continues until the software determines that sufficient valid data has been collected or after a few successive rejections (usually after 3 times). - Then, the software program preferably performs an algorithm for calculating some medical parameters from the sampled data, such as the calculation of systolic and diastolic blood pressure using a method as disclosed in the previously described U.S. Pat. No. 4,418,700, which is hereby incorporated by reference as if fully set forth herein.
- The calculated parameters are then preferably stored in
memory 105. The data stored inmemory 105 is preferably transmitted togateway device 110 periodically, or alternatively or additionally after manual operation ofpanic button 116. - The calculated parameters are also optionally and preferably displayed on a local LCD display (124), so the user can view the last medical results locally.
- More preferably, data for all medical parameters that are sent to remote server (114) are sent according to a security protocol for maintaining the privacy of the user.
- Furthermore, the software program preferably performs another algorithm for generating an alert if the medical parameters have values beyond or otherwise outside of the normal expected values.
- Although a one-way link from
device 101 togateway device 110 may be used,device 101 preferably features a two-way communication link as shown forlink 121, for establishing more reliable communication withgateway device 110. Examples ofcommunication units 104, 107 include but are not limited to a nRF401 UHF transceiver (Nordic), which operates in the universal ISM band (433.92 Mhz), an infrared transceiver, and a “Bluetooth” protocol enabled-transceiver operating bi-directionally in the 2.4 GHz band. -
Device 101 preferably has its own unique identifier, stored in non-volatile data storage, more preferably inmemory 105. Eachtime device 101 sends a wireless message togateway device 110,device 101 also preferably sends the unique identifier togateway device 110, although optionally the identifier may be sent only periodically, for example once per day.Gateway device 110 also preferably sends a message to aparticular device 101 by including the device identifier in the message, thereby specifying which such device should receive the message. - As previously described,
device 101 preferably has its own real time clock 117. For periodic monitoring of the user, real time clock 117 is preferably used to provide a time tag for each set of results. This time tag is very important for continuous monitoring of the user for long periods of time. By examining the data recorded over of the user for long period of time, a change or alteration in the health condition of the user may be detected. Real time clock 117 may optionally be implemented by separate hardware such as RTC8564 (EPSON, US) for example, or alternatively by a software program for operation by processingunit 103. -
Device 101 also preferably features a power source such as abattery 106, which powersdevice 101. Examples of suitable batteries include but are not limited to the silver oxide coin battery model 386 (Panasonic, Japan) having 150 mAh in capacity with a pulse burst of 75 mA for a short period of time (about 5 sec for each pulse).Battery 106 optionally and preferably contains enough energy to power the device for more than one year of operation without being replaced. - FIG. 2 shows an exploded view of the exemplary device according to FIG. 1. As shown, the device features
sensor 102, shown with the preferred but exemplary implementation of a piezoceramic sensor as previously described. The device also optionally and preferably featuresbattery 106, and a push button 316 (for optional implementation of the alarm button of the device of FIG. 1).Battery 106 may optionally be replaced with a plurality of smaller batteries (not shown). The device preferably features a processor 314 (which may optionally be similar or identical to the processing unit of the device of FIG. 1). - For this exemplary implementation,
sensor 102 is in physical contact with ananvil 300.Anvil 300 preferably features aprotrusion 302 which presses against the skin of the wrist of the subject (not shown), more preferably at a pulse point.Protrusion 302 therefore receives pressure with each pulse of the blood of the subject. This pressure is transduced throughanvil 300 tosensor 102, which then emits voltage to form a signal, preferably according to a linear output. - This signal is then received by
processor 314, which preferably extracts medical information from the measurement of the physiological parameter.Processor 314 optionally and preferably features acrystal oscillator 314, for stabilizing the internal clock ofprocessor 314.Processor 314 is also preferably in contact with the real time clock of the device (not shown). Also not shown are the extended memory, transceiver (communication unit), A/D converter and analog front end of the device. -
Processor 314,oscillator 312 andpush button 316 are all preferably mounted on aPCB board 308.PCB board 308 is then preferably sandwiched betweenbattery 106 and adevice cover 304.Device cover 304 preferably features a soft cover, which may be rubber for example, for enabling the user to locate and depress the alarm button throughpush button 316. - An o-
ring 310 is preferably used for waterproof sealing between the upper and the bottom parts of the device.Anvil 300 then is held betweensensor 102 and the skin of the user (not shown), for example by being affixed tosensor 102 with an adhesive substance. - According to an alternative implementation of the device of FIGS. 1 and 2,
sensor 102 andanvil 300 could optionally be located in the wristband for affixing the device to the wrist of the user (not shown). - FIG. 3 is a flow chart of the operation of the device. As the device software begins operation for the first time, the software preferably makes some initializations using default values. Once the device has been initialized, the software preferably triggers a watchdog function shown as a “Watchdog” process, and then enters a sleeping mode for saving battery life, shown as a “Sleep” process.
- If the end of a watchdog time period is reached, the device is assumed to have a fault in its operation, and a master reset is preferably initiated automatically.
- The device is preferably “woken up” according to one of three triggers. First, the device is preferably woken up when the user presses a panic button manually. This process is shown by the “Alarm” state. The device then preferably immediately starts a transmission to the gateway device, containing a distress indication and the device identifier. Then the device enters a receiving mode for a few seconds, waiting for acknowledge (ACK) from the gateway device. This process is shown as a “TX/RX” state.
- If the acknowledge message is not received within this period of time a repeated message is initiated. Additional transmissions are initiated, if necessary. However, if after a predefined number of repeated times an acknowledge message is not received, an error message is stored within a log and no more tries are made. More preferably an indication LED starts blinking for a few seconds, optionally with an audible alarm. Then, the process returns to the “Sleep” state.
- After receiving acknowledge, the process turns to “Supervise” state, where the device collects data from its sensors, preferably calculates some medical information concerning the current physiological status of the user. Then, it turns into “Tx/Rx” state, where the device transmits a message containing the identifier, and the calculated medical parameters. And if the received ACK contains no commands it returns to the “Sleep” state, otherwise it does the command and sends an ACK to the gateway. The gateway returns an ACK with another command to continue or without a command to terminate this process. After doing the last command the device returns to the “Sleep” state.
- In the next case where the device exits its “Sleep” state, an external real time clock signals the device to execute an automatic check. Then, the process enters “Supervise” state as discussed in the above paragraph, only that this time for saving battery life, the device initiate the “Tx/Rx” process only once for a few successive times sending all the accumulated data in one transmission. Then, the device preferably enters a “Sleep” state unless the measured parameters exceed a predefined threshold at least once, but preferably for a few successive measurements. In this case, the device initiates an automatic alarm entering the “Alarm” state, if the device has permission to do so, as previously described.
- When a timer for a supervise process has been running or after an alarm, the device preferably exercises an automatic check as described above, and after that initiates a transmission to the gateway device including all the data collected after the last transmission. Then the device preferably waits for acknowledge, preferably repeating the transmission again if not receiving such an acknowledge message. In the acknowledge message, a command for the device can be stored. In such a case the device performs this command and then it sends an acknowledge message to the gateway device. This process may optionally continue until an acknowledge message without a command is received, after which the device preferably returns to sleep mode.
- In the third case, the device exit “Sleep” mode if of technical reasons a technician wants to change the operation software, the device enters “Boot Loader” state where a new software is loaded “on the fly” without a need to disconnect the batteries.
- FIG. 4 describes an exemplary message format for exchanging messages between the device and the gateway device. Every message preferably starts with a preamble STX byte (hex 7E), followed by a byte which contains the number of bytes in the current message, and three bytes of address, followed by a command byte and its corresponding data bytes. This is followed by two bytes of CRC and an ETX byte (hex 7B).
- As such, the message is a variable length message with strong error detection and correction method for enhanced communication reliability. Each message optionally and preferably contains a low battery indication, if necessary.
- In case of a unidirectional communication link between the device and the gateway, a repeated message is preferably transmitted for a predefined number of times, such as 20 times for example, after which the device preferably enters a sleeping mode if no answer is received.
- In case of a bi-directional link, for each message sent to the gateway device, an acknowledge message is preferably returned by the gateway device and vise versa. This message may also contain a command for the device encoded in the CMD byte within the message. Commands could optionally include, but are not limited to, one or more of the following:
- 1) Get/Set service type
- 2) Get/Set device ID
- 3) Set interval between successive medical checking
- 4) Set interval between successive supervision transmissions
- 5) Set Time and date
- 6) Set threshold for automatic alerts
- 7) Set device calibration
- Each time the device sends a message to the gateway, it may optionally contain a Battery OK/Battery Low indication for the battery situation. This signal preferably appears three months before the battery finishes, enough time to ask the user to replace the battery.
- Each time the device sends a supervise-type message to the gateway, it preferably sends also all the medical data stored in its memory with that message.
- Each time the gateway device sends a command back to the device, the device preferably returns an acknowledge message with a 3 bit message serial number to the gateway device, in order to fulfill a full handshake between the two. If the gateway device does not receive acknowledge from the device within a few seconds, the gateway device preferably sends its transmission message again with the same serial number. The message may even be repeated a few times, each time waiting for acknowledge. If acknowledge is not received, a logbook is updated with an error message, and more preferably an indication LED is turned on for error indication.
- It will be appreciated that the above descriptions are intended only to serve as examples, and that many other embodiments are possible within the spirit and the scope of the present invention.
Claims (35)
1. A device for measuring at least one physiological parameter of a subject, comprising:
(a) a fastening article for being fastened to a wrist of the user;
(b) a sensor for measuring at least one physiological parameter of the user, said sensor being in contact with at least a portion of said wrist and said sensor being attached to said fastening article; and
(c) a processor for receiving a signal from said sensor and for converting said at least one measurement to form medical information.
2. The device of claim 1 , wherein said sensor is an analog sensor, the device further comprising an A/D (analog to digital) converter for receiving an analog signal from said sensor and for converting said analog signal to a digital signal, said digital signal being sent to said processor.
3. The device of claim 2 , wherein a rate of sampling by said A/D converter is determined by said processor.
4. The device of claim 3 , wherein said rate of sampling is at least partially determined according to a type of physiological parameter being measured.
5. The device of claim 1 , wherein said physiological parameter is heart-related.
6. The device of claim 5 , wherein said physiological parameter includes at least one of heart rate and blood pressure.
7. The device of claim 6 , wherein said sensor is selected from the group consisting of a piezoceramic transducer, a piezoelectric transducer, a resistive strain gauge and a pressure sensor with fiber-optic components.
8. The device of claim 5 , wherein said physiological parameter includes variability in heart rate.
9. The device of claim 5 , wherein said physiological parameter includes breathing rate.
10. The device of claim 5 , wherein said physiological parameter includes at least one of arrhythmia and overall cardiac rhythm.
11. The device of claim 5 , wherein said physiological parameter includes body movements.
12. The device of claim 11 , wherein said body movements include presence of abnormal body movements.
13. The device of claim 5 , wherein said physiological parameter includes body temperature.
14. The device of claim 1 , further comprising:
(d) a non-volatile memory for storing at least one instruction for execution by said processor.
15. The device of claim 1 , further comprising:
(e) a communication unit for at least transmitting data.
16. The device of claim 15 , wherein said communication unit also transmits a device identifier for uniquely identifying the device.
17. The device of claim 15 , wherein said communication unit also receives data.
18. The device of claim 1 , wherein said fastening article is a wristband.
19. A system for measuring at least one physiological parameter of a subject, comprising:
(a) a device for measuring the at least one physiological parameter, comprising:
(i) a fastening article for being fastened to a wrist of the user;
(ii) a sensor for measuring at least one physiological parameter of the user, said sensor being in contact with at least a portion of said wrist and said sensor being attached to said fastening article;
(iii) a communication unit for at least transmitting data; and
(b) a gateway device for receiving said transmitted data for being monitored.
20. The system of claim 19 , wherein said transmitted data is monitored manually.
21. The system of claim 20 , further comprising:
(c) a remote server in communication with said gateway device, said remote server providing said transmitted data to a human operator for manual monitoring.
22. The system of claim 21 , wherein at least one of a communication link between said gateway device and said remote server includes a telephonic connection.
23. The system of claim 19 , wherein said transmitted data is monitored at least partially automatically by said gateway device.
24. The system of claim 19 , wherein said device and said gateway device communicate bi-directionally, such that a message transmitted from said device is acknowledged by said gateway device, and such that if said gateway device does not acknowledge correct reception of said message, said device transmits said message again.
25. The system of claim 19 , wherein said device for measuring the at least one physiological parameter further comprises:
(iv) a processor for receiving a signal from said sensor and for converting at least one measurement to form medical information.
26. The system of claim 19 , wherein at least one of a communication link between said device and said gateway device is a wireless link.
27. The system of claim 19 , wherein at least one of a communication link between said device and said gateway device is a wired link.
28. The system of claim 19 , wherein said communication unit of said device also receives data, such that communication between said device and said gateway device includes an acknowledge procedure.
29. The system of claim 19 , wherein said device automatically performs a measurement of the physiological parameter upon manual activation of an alarm function by the subject.
30. The system of claim 29 , wherein said data is automatically transmitted to said gateway device upon said manual activation.
31. The system of claim 19 , wherein said device automatically and periodically performs a measurement of the physiological parameter.
32. The system of claim 31 , wherein said data is automatically transmitted to said gateway device if said measurement is outside of an acceptable range.
33. The system of claim 32 , wherein said measurement is combined with another measurement of at least one other parameter to determine if said measurements are outside of said acceptable range.
34. A method for monitoring a physiological parameter of a user, comprising:
providing a device for monitoring the physiological parameter, said device being attached to at least a portion of the user at a pulse point of the user;
monitoring the physiological parameter through said pulse point; and
if a level of the physiological parameter of the user is outside of an expected range, transmitting an alarm.
35. A device for measuring at least one physiological parameter of a subject, comprising:
(a) a fastening article for being fastened to a wrist of the user;
(b) a piezoceramic sensor for measuring at least one physiological parameter of the user at a pulse point of said wrist and said sensor being attached to said fastening article; and
(c) a processor for receiving a signal from said sensor and for converting said at least one measurement to form medical information.
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/006,357 US20030107487A1 (en) | 2001-12-10 | 2001-12-10 | Method and device for measuring physiological parameters at the wrist |
EP11163908A EP2361555A3 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
EP02793300A EP1459274A4 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
PCT/IL2002/000995 WO2003050643A2 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
US10/497,169 US7598878B2 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
JP2003551635A JP2005511223A (en) | 2001-12-10 | 2002-12-10 | Method and apparatus for measuring physiological parameters at the wrist |
AU2002358956A AU2002358956A1 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
IL16241402A IL162414A0 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
CNA028280024A CN1623175A (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
KR10-2004-7008912A KR20040072648A (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
EP11163901A EP2361550A3 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
US12/571,747 US20100049010A1 (en) | 2001-12-10 | 2009-10-01 | Method and device for measuring physiological parameters at the wrist |
IL210167A IL210167A0 (en) | 2001-12-10 | 2010-12-22 | Method and device for measuring physiological parameters at the wrist |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/006,357 US20030107487A1 (en) | 2001-12-10 | 2001-12-10 | Method and device for measuring physiological parameters at the wrist |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/497,169 Continuation-In-Part US7598878B2 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
PCT/IL2002/000995 Continuation-In-Part WO2003050643A2 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
Publications (1)
Publication Number | Publication Date |
---|---|
US20030107487A1 true US20030107487A1 (en) | 2003-06-12 |
Family
ID=21720497
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/006,357 Abandoned US20030107487A1 (en) | 2001-12-10 | 2001-12-10 | Method and device for measuring physiological parameters at the wrist |
US10/497,169 Expired - Fee Related US7598878B2 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
US12/571,747 Abandoned US20100049010A1 (en) | 2001-12-10 | 2009-10-01 | Method and device for measuring physiological parameters at the wrist |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/497,169 Expired - Fee Related US7598878B2 (en) | 2001-12-10 | 2002-12-10 | Method and device for measuring physiological parameters at the wrist |
US12/571,747 Abandoned US20100049010A1 (en) | 2001-12-10 | 2009-10-01 | Method and device for measuring physiological parameters at the wrist |
Country Status (8)
Country | Link |
---|---|
US (3) | US20030107487A1 (en) |
EP (3) | EP2361550A3 (en) |
JP (1) | JP2005511223A (en) |
KR (1) | KR20040072648A (en) |
CN (1) | CN1623175A (en) |
AU (1) | AU2002358956A1 (en) |
IL (1) | IL162414A0 (en) |
WO (1) | WO2003050643A2 (en) |
Cited By (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030137423A1 (en) * | 2002-01-24 | 2003-07-24 | Ammar Al-Ali | Parallel measurement alarm processor |
US20040027246A1 (en) * | 2002-08-09 | 2004-02-12 | S.I.E.M. S.R.L. | Portable device with sensors for signalling physiological data |
US20050116820A1 (en) * | 2001-12-10 | 2005-06-02 | Rami Goldreich | Method and device for measuring physiological parameters at the wrist |
US20050171418A1 (en) * | 2004-01-08 | 2005-08-04 | Tah-Yeong Lin | Capsule endoscopy system |
US20060229503A1 (en) * | 2005-02-08 | 2006-10-12 | Gunter Fluegel | Device for monitoring vital values of persons needing monitoring |
US20060238333A1 (en) * | 2003-03-21 | 2006-10-26 | Welch Allyn Protocol, Inc. | Personal status physiologic monitor system and architecture and related monitoring methods |
US20070063853A1 (en) * | 2005-08-10 | 2007-03-22 | Derrick Bruce G | Remote tracking and communication device |
US20070112274A1 (en) * | 2005-11-14 | 2007-05-17 | Edwards Lifesciences Corporation | Wireless communication system for pressure monitoring |
US20070204699A1 (en) * | 2006-03-02 | 2007-09-06 | General Electric Company | Remote strain measurement |
WO2007058826A3 (en) * | 2005-11-14 | 2008-04-17 | Edwards Lifesciences Corp | Wireless communication system for pressure monitoring |
US20080114412A1 (en) * | 2004-04-07 | 2008-05-15 | Cardiac Pacemakers, Inc. | System and method for RF transceiver duty cycling in an implantable medical device |
US20090157695A1 (en) * | 2007-08-10 | 2009-06-18 | Smiths Medical Md | Central Server for Medical Devices |
US7583190B2 (en) * | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
US20100016745A1 (en) * | 2005-03-11 | 2010-01-21 | Aframe Digital, Inc. | Mobile wireless customizable health and condition monitor |
US7679407B2 (en) | 2003-04-28 | 2010-03-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems |
USRE41236E1 (en) | 2000-07-05 | 2010-04-20 | Seely Andrew J E | Method and apparatus for multiple patient parameter variability analysis and display |
US20100117835A1 (en) * | 1999-03-03 | 2010-05-13 | Reuven Nanikashvili | System and a method for physiological monitoring |
US7727181B2 (en) | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7737841B2 (en) | 2006-07-14 | 2010-06-15 | Remotemdx | Alarm and alarm management system for remote tracking devices |
US7756561B2 (en) | 2005-09-30 | 2010-07-13 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US20100249541A1 (en) * | 2009-03-27 | 2010-09-30 | LifeWatch Corp. | Methods and Apparatus for Processing Physiological Data Acquired from an Ambulatory Physiological Monitoring Unit |
US20100261977A1 (en) * | 2007-10-03 | 2010-10-14 | Seely Andrew J E | Method and Apparatus for Monitoring Physiological Parameter Variability Over Time for One or More Organs |
US20110078253A1 (en) * | 2008-12-12 | 2011-03-31 | eVent Medical, Inc | System and method for communicating over a network with a medical device |
US7922458B2 (en) | 2002-10-09 | 2011-04-12 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US7936262B2 (en) | 2006-07-14 | 2011-05-03 | Securealert, Inc. | Remote tracking system with a dedicated monitoring center |
WO2011053593A1 (en) * | 2009-10-30 | 2011-05-05 | Mohammed Naji | Medical device |
US20110179123A1 (en) * | 2010-01-19 | 2011-07-21 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US7996187B2 (en) | 2005-02-16 | 2011-08-09 | Card Guard Scientific Survival Ltd. | Method and system for health monitoring |
US8029460B2 (en) | 2005-03-21 | 2011-10-04 | Abbott Diabetes Care Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
US8047811B2 (en) | 2002-10-09 | 2011-11-01 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US20110279262A1 (en) * | 2003-10-30 | 2011-11-17 | Peter Lupoli | Method and system for storing, retrieving, and managing data for tags |
US8071028B2 (en) | 2003-06-12 | 2011-12-06 | Abbott Diabetes Care Inc. | Method and apparatus for providing power management in data communication systems |
US8112138B2 (en) | 2005-06-03 | 2012-02-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US8115635B2 (en) | 2005-02-08 | 2012-02-14 | Abbott Diabetes Care Inc. | RF tag on test strips, test strip vials and boxes |
ITPO20100009A1 (en) * | 2010-09-13 | 2012-03-14 | Daniele Faggi | DISTANCE-BASED ACQUISITION AND MONITORING SYSTEM VIA TELEMATIC NETWORKS OF BIOMETRIC DATA IN SECURITY AREA. |
CN102608426A (en) * | 2012-03-31 | 2012-07-25 | 上海鼎松信息技术有限公司 | Master controller and method applied to automatically detecting abnormal state of wrist strap |
US8232876B2 (en) | 2008-03-07 | 2012-07-31 | Securealert, Inc. | System and method for monitoring individuals using a beacon and intelligent remote tracking device |
US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device |
WO2013006680A1 (en) * | 2011-07-05 | 2013-01-10 | Collar ID, LLC | Apparatus and methods for sensing a parameter with a restraint device |
US8467972B2 (en) | 2009-04-28 | 2013-06-18 | Abbott Diabetes Care Inc. | Closed loop blood glucose control algorithm analysis |
US8514070B2 (en) | 2010-04-07 | 2013-08-20 | Securealert, Inc. | Tracking device incorporating enhanced security mounting strap |
US8560082B2 (en) | 2009-01-30 | 2013-10-15 | Abbott Diabetes Care Inc. | Computerized determination of insulin pump therapy parameters using real time and retrospective data processing |
US8574182B2 (en) | 2005-08-01 | 2013-11-05 | Collar ID, LLC | Restraint device and method of use |
US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US20140009283A1 (en) * | 2002-05-08 | 2014-01-09 | Resource Consortium Limited | Method and system for remotely monitoring a user |
US8639339B2 (en) | 2004-04-07 | 2014-01-28 | Cardiac Pacemakers, Inc. | System and method for RF wake-up of implantable medical device |
US8679011B2 (en) | 2002-09-03 | 2014-03-25 | Omni Medsci, Inc. | System and method for voice control of medical devices |
US20140107449A1 (en) * | 2012-10-12 | 2014-04-17 | Roche Diagnostics Operations, Inc. | Communication protocol improvement to recover data from a continuous glucose monitor |
US20140132413A1 (en) * | 2012-11-12 | 2014-05-15 | Covidien Lp | Systems and methods for patient monitoring |
US20140171809A1 (en) * | 2003-04-23 | 2014-06-19 | Peter M. Bonutti | Monitoring apparatus and other devices |
US8798934B2 (en) | 2009-07-23 | 2014-08-05 | Abbott Diabetes Care Inc. | Real time management of data relating to physiological control of glucose levels |
US8797210B2 (en) | 2006-07-14 | 2014-08-05 | Securealert, Inc. | Remote tracking device and a system and method for two-way voice communication between the device and a monitoring center |
US20140320309A1 (en) * | 2011-07-14 | 2014-10-30 | Jinjing Zhang | Cardiac Electricity and Impedance Monitoring Mobile Network Terminal Device Having Function of Micro Current Release |
CN104510452A (en) * | 2014-12-30 | 2015-04-15 | 江苏华阳电器有限公司 | Portable heart rhythm and body temperature real-time detector |
ES2538040A1 (en) * | 2013-12-16 | 2015-06-16 | Ineuron Health Systems, S.L. | Device, system and method for the non-invasive measurement of physiological data (Machine-translation by Google Translate, not legally binding) |
CN104872942A (en) * | 2015-06-01 | 2015-09-02 | 深圳市浪尖设计有限公司 | Smart bracelet |
WO2015139522A1 (en) * | 2014-03-21 | 2015-09-24 | 辛勤 | Wrist-type apparatus used for health monitoring |
CN105005194A (en) * | 2015-07-28 | 2015-10-28 | 广东欧珀移动通信有限公司 | Prompting method and device and smart watch |
US9220430B2 (en) | 2013-01-07 | 2015-12-29 | Alivecor, Inc. | Methods and systems for electrode placement |
CN105261164A (en) * | 2015-10-23 | 2016-01-20 | 小米科技有限责任公司 | Message prompting method and apparatus |
EP2851756A3 (en) * | 2013-09-18 | 2016-01-20 | Suzhou Lonshine Technologies Co. | Integrated smart watch |
US9247911B2 (en) | 2013-07-10 | 2016-02-02 | Alivecor, Inc. | Devices and methods for real-time denoising of electrocardiograms |
US9254092B2 (en) | 2013-03-15 | 2016-02-09 | Alivecor, Inc. | Systems and methods for processing and analyzing medical data |
US9254095B2 (en) | 2012-11-08 | 2016-02-09 | Alivecor | Electrocardiogram signal detection |
US9351654B2 (en) | 2010-06-08 | 2016-05-31 | Alivecor, Inc. | Two electrode apparatus and methods for twelve lead ECG |
US9420956B2 (en) | 2013-12-12 | 2016-08-23 | Alivecor, Inc. | Methods and systems for arrhythmia tracking and scoring |
CN106209150A (en) * | 2016-07-12 | 2016-12-07 | 陕西理工大学 | A kind of computer radio data collector |
US9636056B2 (en) | 2002-01-24 | 2017-05-02 | Masimo Corporation | Physiological trend monitor |
US9649042B2 (en) | 2010-06-08 | 2017-05-16 | Alivecor, Inc. | Heart monitoring system usable with a smartphone or computer |
US9662053B2 (en) | 2012-06-22 | 2017-05-30 | Fitbit, Inc. | Physiological data collection |
US20170172463A1 (en) * | 2005-03-11 | 2017-06-22 | Nrv-Wellness, Llc | Mobile wireless customizable health and condition monitor |
US9775548B2 (en) | 2015-05-28 | 2017-10-03 | Fitbit, Inc. | Heart rate sensor with high-aspect-ratio photodetector element |
US9839363B2 (en) | 2015-05-13 | 2017-12-12 | Alivecor, Inc. | Discordance monitoring |
US9872087B2 (en) | 2010-10-19 | 2018-01-16 | Welch Allyn, Inc. | Platform for patient monitoring |
US10178973B2 (en) | 2012-06-22 | 2019-01-15 | Fitbit, Inc. | Wearable heart rate monitor |
US10216893B2 (en) | 2010-09-30 | 2019-02-26 | Fitbit, Inc. | Multimode sensor devices |
US10342495B2 (en) | 2013-05-17 | 2019-07-09 | Nokia Technologies Oy | Method and system for providing an early risk recognition monitoring |
US10353430B2 (en) | 2017-08-07 | 2019-07-16 | Samsung Electronics Co., Ltd. | Wearable device and electronic apparatus |
US10433739B2 (en) | 2016-04-29 | 2019-10-08 | Fitbit, Inc. | Multi-channel photoplethysmography sensor |
US10512407B2 (en) | 2013-06-24 | 2019-12-24 | Fitbit, Inc. | Heart rate data collection |
US10568525B1 (en) | 2015-12-14 | 2020-02-25 | Fitbit, Inc. | Multi-wavelength pulse oximetry |
EP3654140A3 (en) * | 2014-10-28 | 2020-08-19 | Samsung Electronics Co., Ltd. | Wearable electronic device |
US11051706B1 (en) | 2017-04-07 | 2021-07-06 | Fitbit, Inc. | Multiple source-detector pair photoplethysmography (PPG) sensor |
US11090003B2 (en) * | 2013-09-09 | 2021-08-17 | Healthy.Io Ltd. | Systems for personal portable wireless vital signs scanner |
US11096601B2 (en) | 2012-06-22 | 2021-08-24 | Fitbit, Inc. | Optical device for determining pulse rate |
US11206989B2 (en) | 2015-12-10 | 2021-12-28 | Fitbit, Inc. | Light field management in an optical biological parameter sensor |
US11259707B2 (en) | 2013-01-15 | 2022-03-01 | Fitbit, Inc. | Methods, systems and devices for measuring heart rate |
Families Citing this family (252)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002080762A1 (en) | 2001-04-06 | 2002-10-17 | Medic4All Inc. | A physiological monitoring system for a computational device of a human subject |
JP4449055B2 (en) * | 2003-11-27 | 2010-04-14 | 日本光電工業株式会社 | Biological signal data transmission / reception system and biological signal data transmission / reception method |
DE102004027044A1 (en) * | 2004-06-02 | 2005-12-29 | Mhm Harzbecher Medizintechnik Gmbh | Apparatus and method for operating a patient monitor |
US20060004294A1 (en) * | 2004-07-02 | 2006-01-05 | Suunto Oy | Method and heart-rate monitor |
US9820658B2 (en) * | 2006-06-30 | 2017-11-21 | Bao Q. Tran | Systems and methods for providing interoperability among healthcare devices |
US7993276B2 (en) | 2004-10-15 | 2011-08-09 | Pulse Tracer, Inc. | Motion cancellation of optical input signals for physiological pulse measurement |
DE202005000310U1 (en) * | 2005-01-10 | 2006-02-16 | King, Rudolf C., Dr.jur. | Portable warning device for persons with automatic indication and storage of the last known location and immediate verification by a communication unit |
US8618930B2 (en) * | 2005-03-11 | 2013-12-31 | Aframe Digital, Inc. | Mobile wireless customizable health and condition monitor |
US8912908B2 (en) | 2005-04-28 | 2014-12-16 | Proteus Digital Health, Inc. | Communication system with remote activation |
EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
US8802183B2 (en) | 2005-04-28 | 2014-08-12 | Proteus Digital Health, Inc. | Communication system with enhanced partial power source and method of manufacturing same |
US8730031B2 (en) | 2005-04-28 | 2014-05-20 | Proteus Digital Health, Inc. | Communication system using an implantable device |
US9198608B2 (en) | 2005-04-28 | 2015-12-01 | Proteus Digital Health, Inc. | Communication system incorporated in a container |
US8836513B2 (en) | 2006-04-28 | 2014-09-16 | Proteus Digital Health, Inc. | Communication system incorporated in an ingestible product |
US20060276870A1 (en) * | 2005-06-03 | 2006-12-07 | Mcginnis William J | Osseus stimulating electrodes |
KR100732600B1 (en) * | 2005-07-21 | 2007-06-27 | 삼성전자주식회사 | Portable device having biosignal-measuring instrument |
JP5714210B2 (en) | 2005-09-01 | 2015-05-07 | プロテウス デジタル ヘルス, インコーポレイテッド | Implantable wireless communication system |
US7760082B2 (en) * | 2005-09-21 | 2010-07-20 | Chon Meng Wong | System and method for active monitoring and diagnostics of life signs using heartbeat waveform and body temperature remotely giving the user freedom to move within its vicinity without wires attachment, gel, or adhesives |
JP2007105316A (en) * | 2005-10-14 | 2007-04-26 | Konica Minolta Sensing Inc | Bioinformation measuring instrument |
WO2007083314A2 (en) * | 2006-01-23 | 2007-07-26 | Card Guard Scientific Survival Ltd. | A health monitor and a method for health monitoring |
GB0603006D0 (en) | 2006-02-15 | 2006-03-29 | Dialog Devices Ltd | Assessing blood supply to a peripheral portion of an animal |
US20070197887A1 (en) * | 2006-02-17 | 2007-08-23 | Medwave, Inc. | Noninvasive vital signs sensor |
CN101400296B (en) * | 2006-02-28 | 2012-11-07 | 皇家飞利浦电子股份有限公司 | Biometric monitor with electronics disposed on or in a neck collar |
US8920343B2 (en) | 2006-03-23 | 2014-12-30 | Michael Edward Sabatino | Apparatus for acquiring and processing of physiological auditory signals |
JP2009544338A (en) | 2006-05-02 | 2009-12-17 | プロテウス バイオメディカル インコーポレイテッド | Treatment regimen customized to the patient |
KR100755079B1 (en) * | 2006-06-30 | 2007-09-06 | 삼성전자주식회사 | Biosignal-measuring instrument |
EP2087589B1 (en) | 2006-10-17 | 2011-11-23 | Proteus Biomedical, Inc. | Low voltage oscillator for medical devices |
EP2083680B1 (en) | 2006-10-25 | 2016-08-10 | Proteus Digital Health, Inc. | Controlled activation ingestible identifier |
US8214007B2 (en) * | 2006-11-01 | 2012-07-03 | Welch Allyn, Inc. | Body worn physiological sensor device having a disposable electrode module |
EP2069004A4 (en) | 2006-11-20 | 2014-07-09 | Proteus Digital Health Inc | Active signal processing personal health signal receivers |
US8157730B2 (en) * | 2006-12-19 | 2012-04-17 | Valencell, Inc. | Physiological and environmental monitoring systems and methods |
US8652040B2 (en) | 2006-12-19 | 2014-02-18 | Valencell, Inc. | Telemetric apparatus for health and environmental monitoring |
US20080171304A1 (en) * | 2007-01-11 | 2008-07-17 | Mcginnis William J | Dental implant kit and method of using same |
US20080172106A1 (en) * | 2007-01-11 | 2008-07-17 | Mcginnis William J | Osteogenic stimulus device, kit and method of using thereof |
ES2930588T3 (en) | 2007-02-01 | 2022-12-19 | Otsuka Pharma Co Ltd | Ingestible Event Marker Systems |
KR101528748B1 (en) | 2007-02-14 | 2015-06-15 | 프로테우스 디지털 헬스, 인코포레이티드 | In-body power source having high surface area electrode |
EP2124725A1 (en) | 2007-03-09 | 2009-12-02 | Proteus Biomedical, Inc. | In-body device having a multi-directional transmitter |
US9270025B2 (en) | 2007-03-09 | 2016-02-23 | Proteus Digital Health, Inc. | In-body device having deployable antenna |
US8115618B2 (en) | 2007-05-24 | 2012-02-14 | Proteus Biomedical, Inc. | RFID antenna for in-body device |
US11607152B2 (en) | 2007-06-12 | 2023-03-21 | Sotera Wireless, Inc. | Optical sensors for use in vital sign monitoring |
US8419649B2 (en) | 2007-06-12 | 2013-04-16 | Sotera Wireless, Inc. | Vital sign monitor for measuring blood pressure using optical, electrical and pressure waveforms |
US11330988B2 (en) | 2007-06-12 | 2022-05-17 | Sotera Wireless, Inc. | Body-worn system for measuring continuous non-invasive blood pressure (cNIBP) |
US8602997B2 (en) | 2007-06-12 | 2013-12-10 | Sotera Wireless, Inc. | Body-worn system for measuring continuous non-invasive blood pressure (cNIBP) |
EP2203910B1 (en) * | 2007-09-19 | 2013-01-23 | Koninklijke Philips Electronics N.V. | Method and apparatus for detecting an abnormal situation |
FI2192946T3 (en) | 2007-09-25 | 2022-11-30 | In-body device with virtual dipole signal amplification | |
US8251903B2 (en) | 2007-10-25 | 2012-08-28 | Valencell, Inc. | Noninvasive physiological analysis using excitation-sensor modules and related devices and methods |
US20090171176A1 (en) * | 2007-12-28 | 2009-07-02 | Nellcor Puritan Bennett Llc | Snapshot Sensor |
US20090216090A1 (en) * | 2008-02-26 | 2009-08-27 | Sinbon Electronics Company Ltd. | Household health monitoring system |
AU2009221781B2 (en) | 2008-03-05 | 2014-12-11 | Otsuka Pharmaceutical Co., Ltd. | Multi-mode communication ingestible event markers and systems, and methods of using the same |
IL197532A0 (en) * | 2008-03-21 | 2009-12-24 | Lifescan Scotland Ltd | Analyte testing method and system |
US8577431B2 (en) | 2008-07-03 | 2013-11-05 | Cercacor Laboratories, Inc. | Noise shielding for a noninvasive device |
US20100030040A1 (en) | 2008-08-04 | 2010-02-04 | Masimo Laboratories, Inc. | Multi-stream data collection system for noninvasive measurement of blood constituents |
MY154234A (en) | 2008-07-08 | 2015-05-15 | Proteus Digital Health Inc | Ingestible event marker data framework |
AU2009281876B2 (en) | 2008-08-13 | 2014-05-22 | Proteus Digital Health, Inc. | Ingestible circuitry |
KR101192690B1 (en) | 2008-11-13 | 2012-10-19 | 프로테우스 디지털 헬스, 인코포레이티드 | Ingestible therapy activator system, therapeutic device and method |
US8055334B2 (en) | 2008-12-11 | 2011-11-08 | Proteus Biomedical, Inc. | Evaluation of gastrointestinal function using portable electroviscerography systems and methods of using the same |
US8487772B1 (en) | 2008-12-14 | 2013-07-16 | Brian William Higgins | System and method for communicating information |
US9659423B2 (en) | 2008-12-15 | 2017-05-23 | Proteus Digital Health, Inc. | Personal authentication apparatus system and method |
WO2013012869A1 (en) | 2011-07-21 | 2013-01-24 | Proteus Digital Health, Inc. | Mobile communication device, system, and method |
US9439566B2 (en) | 2008-12-15 | 2016-09-13 | Proteus Digital Health, Inc. | Re-wearable wireless device |
TWI424832B (en) | 2008-12-15 | 2014-02-01 | Proteus Digital Health Inc | Body-associated receiver and method |
EP3395333A1 (en) | 2009-01-06 | 2018-10-31 | Proteus Digital Health, Inc. | Pharmaceutical dosages delivery system |
JP2012514799A (en) | 2009-01-06 | 2012-06-28 | プロテウス バイオメディカル インコーポレイテッド | Methods and systems for ingestion related biofeedback and individual pharmacotherapy |
EP2400884B1 (en) | 2009-02-25 | 2018-03-07 | Valencell, Inc. | Light-guiding devices and monitoring devices incorporating same |
US9750462B2 (en) | 2009-02-25 | 2017-09-05 | Valencell, Inc. | Monitoring apparatus and methods for measuring physiological and/or environmental conditions |
US8788002B2 (en) | 2009-02-25 | 2014-07-22 | Valencell, Inc. | Light-guiding devices and monitoring devices incorporating same |
CN101833839A (en) * | 2009-03-13 | 2010-09-15 | 深圳富泰宏精密工业有限公司 | Multifunctional portable electronic device |
WO2010111403A2 (en) | 2009-03-25 | 2010-09-30 | Proteus Biomedical, Inc. | Probablistic pharmacokinetic and pharmacodynamic modeling |
CN102458236B (en) | 2009-04-28 | 2016-01-27 | 普罗秋斯数字健康公司 | The Ingestible event marker of high reliability and using method thereof |
US9149423B2 (en) | 2009-05-12 | 2015-10-06 | Proteus Digital Health, Inc. | Ingestible event markers comprising an ingestible component |
US8672854B2 (en) * | 2009-05-20 | 2014-03-18 | Sotera Wireless, Inc. | System for calibrating a PTT-based blood pressure measurement using arm height |
US10555676B2 (en) | 2009-05-20 | 2020-02-11 | Sotera Wireless, Inc. | Method for generating alarms/alerts based on a patient's posture and vital signs |
US11896350B2 (en) | 2009-05-20 | 2024-02-13 | Sotera Wireless, Inc. | Cable system for generating signals for detecting motion and measuring vital signs |
US9596999B2 (en) | 2009-06-17 | 2017-03-21 | Sotera Wireless, Inc. | Body-worn pulse oximeter |
US20110034788A1 (en) * | 2009-08-04 | 2011-02-10 | Nellcor Puritan Bennett Llc | Methods and apparatus for using multiple sensors to measure differential blood transport time in a patient |
US8558563B2 (en) | 2009-08-21 | 2013-10-15 | Proteus Digital Health, Inc. | Apparatus and method for measuring biochemical parameters |
US20110066008A1 (en) | 2009-09-14 | 2011-03-17 | Matt Banet | Body-worn monitor for measuring respiration rate |
US11253169B2 (en) | 2009-09-14 | 2022-02-22 | Sotera Wireless, Inc. | Body-worn monitor for measuring respiration rate |
US20110066044A1 (en) | 2009-09-15 | 2011-03-17 | Jim Moon | Body-worn vital sign monitor |
US10806351B2 (en) | 2009-09-15 | 2020-10-20 | Sotera Wireless, Inc. | Body-worn vital sign monitor |
US8527038B2 (en) | 2009-09-15 | 2013-09-03 | Sotera Wireless, Inc. | Body-worn vital sign monitor |
US8364250B2 (en) | 2009-09-15 | 2013-01-29 | Sotera Wireless, Inc. | Body-worn vital sign monitor |
US8321004B2 (en) | 2009-09-15 | 2012-11-27 | Sotera Wireless, Inc. | Body-worn vital sign monitor |
US10420476B2 (en) | 2009-09-15 | 2019-09-24 | Sotera Wireless, Inc. | Body-worn vital sign monitor |
TW201110935A (en) * | 2009-09-18 | 2011-04-01 | Univ Nat Yang Ming | Remote patient monitoring system and method thereof |
US8430817B1 (en) | 2009-10-15 | 2013-04-30 | Masimo Corporation | System for determining confidence in respiratory rate measurements |
US9357921B2 (en) | 2009-10-16 | 2016-06-07 | At&T Intellectual Property I, Lp | Wearable health monitoring system |
US9724016B1 (en) | 2009-10-16 | 2017-08-08 | Masimo Corp. | Respiration processor |
TWI517050B (en) | 2009-11-04 | 2016-01-11 | 普羅托斯數位健康公司 | System for supply chain management |
UA109424C2 (en) | 2009-12-02 | 2015-08-25 | PHARMACEUTICAL PRODUCT, PHARMACEUTICAL TABLE WITH ELECTRONIC MARKER AND METHOD OF MANUFACTURING PHARMACEUTICAL TABLETS | |
US20110178375A1 (en) * | 2010-01-19 | 2011-07-21 | Avery Dennison Corporation | Remote physiological monitoring |
SG182825A1 (en) | 2010-02-01 | 2012-09-27 | Proteus Biomedical Inc | Data gathering system |
US20110208013A1 (en) * | 2010-02-24 | 2011-08-25 | Edwards Lifesciences Corporation | Body Parameter Sensor and Monitor Interface |
US20110213217A1 (en) * | 2010-02-28 | 2011-09-01 | Nellcor Puritan Bennett Llc | Energy optimized sensing techniques |
US10206570B2 (en) * | 2010-02-28 | 2019-02-19 | Covidien Lp | Adaptive wireless body networks |
US20110224564A1 (en) | 2010-03-10 | 2011-09-15 | Sotera Wireless, Inc. | Body-worn vital sign monitor |
US20110224505A1 (en) * | 2010-03-12 | 2011-09-15 | Rajendra Padma Sadhu | User wearable portable communicative device |
US9307928B1 (en) | 2010-03-30 | 2016-04-12 | Masimo Corporation | Plethysmographic respiration processor |
BR112012025650A2 (en) | 2010-04-07 | 2020-08-18 | Proteus Digital Health, Inc. | miniature ingestible device |
US9173594B2 (en) | 2010-04-19 | 2015-11-03 | Sotera Wireless, Inc. | Body-worn monitor for measuring respiratory rate |
US8747330B2 (en) | 2010-04-19 | 2014-06-10 | Sotera Wireless, Inc. | Body-worn monitor for measuring respiratory rate |
US8979765B2 (en) | 2010-04-19 | 2015-03-17 | Sotera Wireless, Inc. | Body-worn monitor for measuring respiratory rate |
US9339209B2 (en) | 2010-04-19 | 2016-05-17 | Sotera Wireless, Inc. | Body-worn monitor for measuring respiratory rate |
US9173593B2 (en) | 2010-04-19 | 2015-11-03 | Sotera Wireless, Inc. | Body-worn monitor for measuring respiratory rate |
US8888700B2 (en) | 2010-04-19 | 2014-11-18 | Sotera Wireless, Inc. | Body-worn monitor for measuring respiratory rate |
KR101048662B1 (en) * | 2010-05-03 | 2011-07-14 | 한국과학기술원 | A body attaching type sensor and monitoring apparatus thereof |
TWI557672B (en) | 2010-05-19 | 2016-11-11 | 波提亞斯數位康健公司 | Computer system and computer-implemented method to track medication from manufacturer to a patient, apparatus and method for confirming delivery of medication to a patient, patient interface device |
US20110291838A1 (en) * | 2010-05-26 | 2011-12-01 | General Electric Company | Alarm Generation Method for Patient Monitoring, Physiological Monitoring Apparatus and Computer Program Product for a Physiological Monitoring Apparatus |
CA2803885A1 (en) * | 2010-06-25 | 2011-12-29 | Drexel University | Non-invasive blood pressure sensor |
EP2635180B1 (en) | 2010-11-02 | 2019-03-06 | CardioNet, Inc. | Medical data collection apparatus and method |
CN101966079A (en) * | 2010-11-18 | 2011-02-09 | 耕者有田科技(北京)有限公司 | Wireless infrared vital sign sensor |
JP2014504902A (en) | 2010-11-22 | 2014-02-27 | プロテウス デジタル ヘルス, インコーポレイテッド | Ingestible device with medicinal product |
US8665096B2 (en) | 2010-12-21 | 2014-03-04 | General Electric Company | Alarm control method, physiological monitoring apparatus, and computer program product for a physiological monitoring apparatus |
US10722131B2 (en) | 2010-12-28 | 2020-07-28 | Sotera Wireless, Inc. | Body-worn system for continuous, noninvasive measurement of cardiac output, stroke volume, cardiac power, and blood pressure |
US8902062B2 (en) * | 2011-01-27 | 2014-12-02 | Honeywell International Inc. | Systems and methods for detection of device displacement and tampering |
US8888701B2 (en) | 2011-01-27 | 2014-11-18 | Valencell, Inc. | Apparatus and methods for monitoring physiological data during environmental interference |
US10098584B2 (en) | 2011-02-08 | 2018-10-16 | Cardiac Pacemakers, Inc. | Patient health improvement monitor |
US20120203076A1 (en) * | 2011-02-08 | 2012-08-09 | Jean Pierre Fatta | Portable Physiological Data Monitoring Device |
CN103491860B (en) | 2011-02-18 | 2016-10-19 | 索泰拉无线公司 | For measuring the optical pickocff of physiological property |
EP2675348B1 (en) | 2011-02-18 | 2019-11-06 | Sotera Wireless, Inc. | Modular wrist-worn processor for patient monitoring |
US9439599B2 (en) | 2011-03-11 | 2016-09-13 | Proteus Digital Health, Inc. | Wearable personal body associated device with various physical configurations |
WO2012140559A1 (en) | 2011-04-11 | 2012-10-18 | Medic4All Ag | Pulse oximetry measurement triggering ecg measurement |
KR101273619B1 (en) * | 2011-06-09 | 2013-06-11 | (주)아람솔루션 | electronical blood pressure measurement apparatus using bluetooth |
CN102499663A (en) * | 2011-06-09 | 2012-06-20 | 李钢坤 | Heart rate vibrator of heart rate sensor |
WO2015112603A1 (en) | 2014-01-21 | 2015-07-30 | Proteus Digital Health, Inc. | Masticable ingestible product and communication system therefor |
US9756874B2 (en) | 2011-07-11 | 2017-09-12 | Proteus Digital Health, Inc. | Masticable ingestible product and communication system therefor |
US9427191B2 (en) | 2011-07-25 | 2016-08-30 | Valencell, Inc. | Apparatus and methods for estimating time-state physiological parameters |
WO2013019494A2 (en) | 2011-08-02 | 2013-02-07 | Valencell, Inc. | Systems and methods for variable filter adjustment by heart rate metric feedback |
WO2013056194A1 (en) * | 2011-10-14 | 2013-04-18 | Zoll Medical Corporation | Automated delivery of medical device support software |
US9247004B2 (en) * | 2011-10-25 | 2016-01-26 | Vital Connect, Inc. | System and method for reliable and scalable health monitoring |
CN102327115B (en) * | 2011-10-31 | 2014-01-29 | 北京超思电子技术股份有限公司 | Heart rate detection equipment |
US9235683B2 (en) | 2011-11-09 | 2016-01-12 | Proteus Digital Health, Inc. | Apparatus, system, and method for managing adherence to a regimen |
US9700222B2 (en) | 2011-12-02 | 2017-07-11 | Lumiradx Uk Ltd | Health-monitor patch |
US9734304B2 (en) | 2011-12-02 | 2017-08-15 | Lumiradx Uk Ltd | Versatile sensors with data fusion functionality |
CN103957777B (en) * | 2011-12-07 | 2018-01-09 | 捷通国际有限公司 | Behavior tracking and update the system |
EP2816950A4 (en) * | 2012-02-22 | 2015-10-28 | Aclaris Medical Llc | Physiological signal detecting device and system |
US8782308B2 (en) | 2012-02-29 | 2014-07-15 | Cardionet, Inc. | Connector interface system for data acquisition |
CN103310585A (en) * | 2012-03-08 | 2013-09-18 | 昆明英地尔软件技术有限公司 | Human body health information acquiring, positioning and danger alarm device |
US9041530B2 (en) | 2012-04-18 | 2015-05-26 | Qualcomm Incorporated | Biometric attribute anomaly detection system with adjusting notifications |
CN102637029A (en) * | 2012-05-08 | 2012-08-15 | 北京华录亿动科技发展有限公司 | Home environment and personal state monitoring and warning system |
US9769868B2 (en) * | 2012-05-31 | 2017-09-19 | Koninklijke Philips N.V. | Measurement device |
US9042596B2 (en) | 2012-06-14 | 2015-05-26 | Medibotics Llc | Willpower watch (TM)—a wearable food consumption monitor |
US9442100B2 (en) | 2013-12-18 | 2016-09-13 | Medibotics Llc | Caloric intake measuring system using spectroscopic and 3D imaging analysis |
US9254099B2 (en) | 2013-05-23 | 2016-02-09 | Medibotics Llc | Smart watch and food-imaging member for monitoring food consumption |
US9536449B2 (en) | 2013-05-23 | 2017-01-03 | Medibotics Llc | Smart watch and food utensil for monitoring food consumption |
US10314492B2 (en) | 2013-05-23 | 2019-06-11 | Medibotics Llc | Wearable spectroscopic sensor to measure food consumption based on interaction between light and the human body |
US9582035B2 (en) | 2014-02-25 | 2017-02-28 | Medibotics Llc | Wearable computing devices and methods for the wrist and/or forearm |
CN103505193B (en) * | 2012-06-19 | 2015-06-10 | 北京超思电子技术股份有限公司 | Wrist strap type physiological information monitoring device |
US9861744B2 (en) * | 2012-06-25 | 2018-01-09 | International Business Machines Corporation | Managing blood glucose levels |
US20140025401A1 (en) * | 2012-07-17 | 2014-01-23 | Peter L. Hagelstein | Data acquisition apparatus configured to acquire data for insurance purposes, and related systems and methods |
US9271897B2 (en) | 2012-07-23 | 2016-03-01 | Proteus Digital Health, Inc. | Techniques for manufacturing ingestible event markers comprising an ingestible component |
SG11201503027SA (en) | 2012-10-18 | 2015-05-28 | Proteus Digital Health Inc | Apparatus, system, and method to adaptively optimize power dissipation and broadcast power in a power source for a communication device |
US20140128754A1 (en) * | 2012-11-08 | 2014-05-08 | Aliphcom | Multimodal physiological sensing for wearable devices or mobile devices |
CN108903920A (en) * | 2013-01-15 | 2018-11-30 | 飞比特公司 | Portable biometric metering monitor and its operating method |
CN108937908B (en) | 2013-01-28 | 2021-08-10 | 瓦伦赛尔公司 | Physiological monitoring device with sensing element decoupled from body motion |
JP2016508529A (en) | 2013-01-29 | 2016-03-22 | プロテウス デジタル ヘルス, インコーポレイテッド | Highly expandable polymer film and composition containing the same |
KR101450815B1 (en) | 2013-01-29 | 2014-10-14 | 인덕대학교 산학협력단 | Physiological signal measuring device |
US10441181B1 (en) | 2013-03-13 | 2019-10-15 | Masimo Corporation | Acoustic pulse and respiration monitoring system |
US9677990B2 (en) | 2014-04-30 | 2017-06-13 | Particles Plus, Inc. | Particle counter with advanced features |
US11579072B2 (en) | 2013-03-15 | 2023-02-14 | Particles Plus, Inc. | Personal air quality monitoring system |
WO2014151929A1 (en) | 2013-03-15 | 2014-09-25 | Proteus Digital Health, Inc. | Personal authentication apparatus system and method |
JP5941240B2 (en) | 2013-03-15 | 2016-06-29 | プロテウス デジタル ヘルス, インコーポレイテッド | Metal detector device, system and method |
US10983040B2 (en) | 2013-03-15 | 2021-04-20 | Particles Plus, Inc. | Particle counter with integrated bootloader |
US11744481B2 (en) | 2013-03-15 | 2023-09-05 | Otsuka Pharmaceutical Co., Ltd. | System, apparatus and methods for data collection and assessing outcomes |
US10352844B2 (en) | 2013-03-15 | 2019-07-16 | Particles Plus, Inc. | Multiple particle sensors in a particle counter |
JP2014180311A (en) * | 2013-03-18 | 2014-09-29 | Shigeki Tateishi | Biometry apparatus and biological monitoring system |
US9529385B2 (en) | 2013-05-23 | 2016-12-27 | Medibotics Llc | Smart watch and human-to-computer interface for monitoring food consumption |
CN108742559B (en) * | 2013-06-03 | 2022-01-07 | 飞比特公司 | Wearable heart rate monitor |
CN103622681B (en) * | 2013-06-04 | 2015-05-13 | 浙江理工大学 | Portable human health detector |
US9662050B2 (en) | 2013-06-21 | 2017-05-30 | Verify Life Sciences LLC | Physiological measurement using wearable device |
US9796576B2 (en) | 2013-08-30 | 2017-10-24 | Proteus Digital Health, Inc. | Container with electronically controlled interlock |
EP3047618B1 (en) | 2013-09-20 | 2023-11-08 | Otsuka Pharmaceutical Co., Ltd. | Methods, devices and systems for receiving and decoding a signal in the presence of noise using slices and warping |
JP2016537924A (en) | 2013-09-24 | 2016-12-01 | プロテウス デジタル ヘルス, インコーポレイテッド | Method and apparatus for use with electromagnetic signals received at frequencies that are not accurately known in advance |
WO2015047015A1 (en) * | 2013-09-30 | 2015-04-02 | 주식회사 휴이노 | System for monitoring blood pressure in real-time |
US10542918B2 (en) | 2013-10-23 | 2020-01-28 | Verily Life Sciences Llc | Modulation of a response signal to distinguish between analyte and background signals |
US9636034B2 (en) | 2013-10-23 | 2017-05-02 | Verily Life Sciences Llc | Non-invasive analyte detection system with modulation source |
US10478075B2 (en) | 2013-10-25 | 2019-11-19 | Qualcomm Incorporated | System and method for obtaining bodily function measurements using a mobile device |
US10052035B2 (en) * | 2013-10-25 | 2018-08-21 | Qualcomm Incorporated | System and method for obtaining bodily function measurements using a mobile device |
CA2832062A1 (en) * | 2013-11-01 | 2015-05-01 | Saskatchewan Telecommunications | Centrally managed lone worker monitoring system and method |
US10084880B2 (en) | 2013-11-04 | 2018-09-25 | Proteus Digital Health, Inc. | Social media networking based on physiologic information |
CN103598879A (en) * | 2013-11-29 | 2014-02-26 | 哈尔滨理工大学科技园发展有限公司 | Wearable vital sign monitor |
US9504425B2 (en) * | 2013-12-16 | 2016-11-29 | Verily Life Sciences Llc | Method of location coordination via wireless protocol between multiple devices |
JP6222257B2 (en) * | 2013-12-25 | 2017-11-01 | セイコーエプソン株式会社 | Biological information measuring device |
CN103823359A (en) * | 2014-01-26 | 2014-05-28 | 苏州智信通电子科技有限公司 | Multifunctional wireless Bluetooth information-storage healthy watch and control method thereof |
US10254804B2 (en) | 2014-02-11 | 2019-04-09 | Apple Inc. | Detecting the limb wearing a wearable electronic device |
US10429888B2 (en) | 2014-02-25 | 2019-10-01 | Medibotics Llc | Wearable computer display devices for the forearm, wrist, and/or hand |
US10758130B2 (en) | 2014-03-31 | 2020-09-01 | Welch Allyn, Inc. | Single site vitals |
CN103908233A (en) * | 2014-04-21 | 2014-07-09 | 河北工业大学 | Monitoring device for physiological parameters of human body |
KR20170008216A (en) * | 2014-05-23 | 2017-01-23 | 삼성전자주식회사 | Adjustable wearable system having a modular sensor platform |
US20150342480A1 (en) * | 2014-05-30 | 2015-12-03 | Microsoft Corporation | Optical pulse-rate sensing |
US20150356860A1 (en) * | 2014-06-05 | 2015-12-10 | Integrity Tracking, Llc | Systems and methods for automatically reporting location change in user monitoring systems |
US9451911B1 (en) | 2014-06-18 | 2016-09-27 | Verily Life Sciences Llc | Test model for wearable devices |
CN105232020A (en) * | 2014-07-08 | 2016-01-13 | 徐庆十 | Optical sensing sphygmomanometer |
US9942232B2 (en) | 2014-07-08 | 2018-04-10 | Verily Life Sciences Llc | User control of data de-identification |
US9910035B1 (en) | 2014-07-16 | 2018-03-06 | Verily Life Sciences Llc | Polyvalent functionalized nanoparticle-based in vivo diagnostic system |
US9874554B1 (en) | 2014-07-16 | 2018-01-23 | Verily Life Sciences Llc | Aptamer-based in vivo diagnostic system |
US9820690B1 (en) | 2014-07-16 | 2017-11-21 | Verily Life Sciences Llc | Analyte detection system |
US9858328B2 (en) | 2014-07-17 | 2018-01-02 | Verily Life Sciences, LLC | Data tagging |
US20160029898A1 (en) | 2014-07-30 | 2016-02-04 | Valencell, Inc. | Physiological Monitoring Devices and Methods Using Optical Sensors |
WO2016022295A1 (en) | 2014-08-06 | 2016-02-11 | Valencell, Inc. | Optical physiological sensor modules with reduced signal noise |
US20180227735A1 (en) * | 2014-08-25 | 2018-08-09 | Phyziio, Inc. | Proximity-Based Attribution of Rewards |
US9386401B2 (en) * | 2014-08-25 | 2016-07-05 | Steven K. Gold | Proximity-based sensing, communicating, and processing of user physiologic information |
JP2016047092A (en) * | 2014-08-27 | 2016-04-07 | セイコーエプソン株式会社 | Biological information detector |
DE212015000214U1 (en) | 2014-09-02 | 2017-05-12 | Apple Inc. | Wearable electronic device |
CN107072541A (en) | 2014-09-09 | 2017-08-18 | 托维克公司 | For utilizing wearable device monitoring individual alertness and the method and apparatus that provides notice |
CN104161501A (en) * | 2014-09-10 | 2014-11-26 | 青岛永通电梯工程有限公司 | Moving data testing method |
US10349870B1 (en) | 2014-09-22 | 2019-07-16 | Verily Life Sciences Llc | Magnetic switching |
US9794653B2 (en) | 2014-09-27 | 2017-10-17 | Valencell, Inc. | Methods and apparatus for improving signal quality in wearable biometric monitoring devices |
US10076286B1 (en) | 2014-10-21 | 2018-09-18 | Verily Life Sciences Llc | Methods and devices for circadian rhythm monitoring |
TWI608826B (en) | 2014-10-31 | 2017-12-21 | 財團法人工業技術研究院 | Optical sensing device and measurement method thereof |
TWI562760B (en) | 2014-11-04 | 2016-12-21 | Univ Nat Taiwan Science Tech | Radial artery blood pressure waveform measuring device |
US9724003B2 (en) * | 2014-11-14 | 2017-08-08 | Intel Corporation | Ultra-low power continuous heart rate sensing in wearable devices |
EP3026523B1 (en) | 2014-11-28 | 2019-08-28 | Nokia Technologies OY | Method and apparatus for contacting skin with sensor equipment |
CN105769118B (en) * | 2014-12-15 | 2019-07-05 | 汇嘉健康生活科技股份有限公司 | Optical fiber inductive layer and its monitoring system |
CN105898896A (en) * | 2014-12-15 | 2016-08-24 | 江南大学 | Wearable body sensor network |
CN105796076B (en) * | 2014-12-31 | 2020-11-06 | 汇嘉健康生活科技股份有限公司 | Optical fiber type continuous detection type blood pressure sensor and wearing device thereof |
CN104622445B (en) * | 2015-01-30 | 2017-02-01 | 中国科学院电子学研究所 | Wireless intelligent multi-physiological-parameter health supervision wrist type equipment |
JP2016158768A (en) * | 2015-02-27 | 2016-09-05 | パイオニア株式会社 | Portable apparatus |
KR101676559B1 (en) * | 2015-03-05 | 2016-11-15 | 서울과학기술대학교 산학협력단 | A low power biological signal measuring instrument and a amplification rate control method of measured signal |
CN104658190B (en) * | 2015-03-22 | 2017-03-08 | 山东艾欧特投资集团有限公司 | A kind of mobile terminal with heartbeat detection and emergency alarm |
US11329683B1 (en) * | 2015-06-05 | 2022-05-10 | Life365, Inc. | Device configured for functional diagnosis and updates |
US9974492B1 (en) | 2015-06-05 | 2018-05-22 | Life365, Inc. | Health monitoring and communications device |
US10560135B1 (en) | 2015-06-05 | 2020-02-11 | Life365, Inc. | Health, wellness and activity monitor |
US10185513B1 (en) | 2015-06-05 | 2019-01-22 | Life365, Inc. | Device configured for dynamic software change |
US11051543B2 (en) | 2015-07-21 | 2021-07-06 | Otsuka Pharmaceutical Co. Ltd. | Alginate on adhesive bilayer laminate film |
US11660436B1 (en) | 2015-08-04 | 2023-05-30 | Verily Life Sciences Llc | Device, system, and formulation for oral delivery of functionalized particles |
US10643745B2 (en) | 2015-09-29 | 2020-05-05 | Jeff Scott Bruno | Systems and methods for determining human performance capacity and utility of a biomedical intervention/neurotechnology device |
US10610158B2 (en) | 2015-10-23 | 2020-04-07 | Valencell, Inc. | Physiological monitoring devices and methods that identify subject activity type |
US10945618B2 (en) | 2015-10-23 | 2021-03-16 | Valencell, Inc. | Physiological monitoring devices and methods for noise reduction in physiological signals based on subject activity type |
US10492709B2 (en) | 2015-11-19 | 2019-12-03 | Verily Life Sciences Llc | Magnetic probes for in vivo capture and detection of extracellular vesicles |
US20180350468A1 (en) * | 2015-11-23 | 2018-12-06 | Paul A. Friedman | Processing physiological electrical data for analyte assessments |
US10250403B2 (en) | 2015-11-23 | 2019-04-02 | International Business Machines Corporation | Dynamic control of smart home using wearable device |
KR101726613B1 (en) * | 2016-04-28 | 2017-04-13 | 조한희 | APPARATUS AND METHOD for measuring bio signal |
CN112022100B (en) * | 2016-05-06 | 2023-12-29 | 上海中医药大学 | Bluetooth pulse diagnosis bracelet and pulse data transmission method |
WO2018009736A1 (en) | 2016-07-08 | 2018-01-11 | Valencell, Inc. | Motion-dependent averaging for physiological metric estimating systems and methods |
KR102051875B1 (en) | 2016-07-22 | 2019-12-04 | 프로테우스 디지털 헬스, 인코포레이티드 | Electromagnetic detection and detection of ingestible event markers |
CN106343973B (en) * | 2016-08-23 | 2020-04-10 | 中国农业大学 | Human body sign detection device |
EP3531901A4 (en) | 2016-10-26 | 2021-01-27 | Proteus Digital Health, Inc. | Methods for manufacturing capsules with ingestible event markers |
CN106798546A (en) * | 2017-03-07 | 2017-06-06 | 铂元智能科技(北京)有限公司 | Data acquisition process terminal |
CN106859667B (en) * | 2017-03-07 | 2020-11-24 | 铂元智能科技(北京)有限公司 | Wireless blood oxygen measuring device |
CN107510447A (en) * | 2017-07-31 | 2017-12-26 | 上海斐讯数据通信技术有限公司 | A kind of wearable device for being used to measure heart rate and measurement heart rate method |
US11331019B2 (en) | 2017-08-07 | 2022-05-17 | The Research Foundation For The State University Of New York | Nanoparticle sensor having a nanofibrous membrane scaffold |
EP3451117B1 (en) | 2017-09-05 | 2023-08-23 | Apple Inc. | Wearable electronic device with electrodes for sensing biological parameters |
CN107485379A (en) * | 2017-09-13 | 2017-12-19 | 丽水市中心医院 | A kind of intelligent vascular pressure monitor |
EP3459447A3 (en) * | 2017-09-26 | 2019-07-10 | Apple Inc. | Optical sensor subsystem adjacent a cover of an electronic device housing |
KR102592077B1 (en) | 2018-08-01 | 2023-10-19 | 삼성전자주식회사 | Apparatus and method for measuring bio-information |
WO2020116527A1 (en) | 2018-12-04 | 2020-06-11 | 旭化成株式会社 | Biological information measurement device |
KR102211498B1 (en) * | 2020-04-22 | 2021-02-04 | 정상화 | A Portable Device for Curing Rhinitis and A System for Caring Rhinitis Having the Same |
CN111700690A (en) * | 2020-06-08 | 2020-09-25 | 四川大学华西医院 | Medical wearable wrist strap |
ES2902101A1 (en) * | 2020-09-24 | 2022-03-24 | Zataca Systems Sl | Wrist bracelet for monitoring of human biochemical, human and environmental environmental parameters in combination with a system of communication modules, storage and artificial intelligence (IA) (Machine-translation by Google Translate, not legally binding) |
CN112545582A (en) * | 2020-12-15 | 2021-03-26 | 天津职业技术师范大学(中国职业培训指导教师进修中心) | Micro-nano operation device and method with expansion function |
KR102351615B1 (en) * | 2021-07-22 | 2022-01-14 | 주식회사 에어위드 | Air quality sensor apparatus |
Family Cites Families (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US635701A (en) | 1899-01-23 | 1899-10-24 | La Fayette Rollins | Flue-cleaner. |
GB1312107A (en) | 1970-09-29 | 1973-04-04 | Orr T | Heartbeat rate monitors |
US3911899A (en) * | 1973-11-08 | 1975-10-14 | Chemetron Corp | Respiration monitoring method and apparatus |
US3926179A (en) | 1974-04-03 | 1975-12-16 | Wisconsin Alumni Res Found | Blood pressure measuring apparatus |
CH591233A5 (en) * | 1976-03-23 | 1977-09-15 | Olten Ag Elektro Apparatebau | |
US4173971A (en) | 1977-08-29 | 1979-11-13 | Karz Allen E | Continuous electrocardiogram monitoring method and system for cardiac patients |
US4331154A (en) | 1979-10-15 | 1982-05-25 | Tech Engineering & Design | Blood pressure and heart rate measuring watch |
DE3018863A1 (en) * | 1980-05-16 | 1981-11-26 | Hellige Gmbh, 7800 Freiburg | HEATED MEASURING METER FOR PHYSIOLOGICAL MEASUREMENTS WITH A BUILT-IN TEMPERATURE-CONTROLLED SWITCH |
US4407295A (en) | 1980-10-16 | 1983-10-04 | Dna Medical, Inc. | Miniature physiological monitor with interchangeable sensors |
US4418700A (en) | 1981-03-11 | 1983-12-06 | Sylvia Warner | Method and apparatus for measurement of heart-related parameters |
US4819860A (en) * | 1986-01-09 | 1989-04-11 | Lloyd D. Lillie | Wrist-mounted vital functions monitor and emergency locator |
JPH082350B2 (en) * | 1987-05-02 | 1996-01-17 | コ−リン電子株式会社 | Pulse wave detector |
US4952928A (en) * | 1988-08-29 | 1990-08-28 | B. I. Incorporated | Adaptable electronic monitoring and identification system |
US4938228A (en) * | 1989-02-15 | 1990-07-03 | Righter William H | Wrist worn heart rate monitor |
US5045839A (en) * | 1990-03-08 | 1991-09-03 | Rand G. Ellis | Personnel monitoring man-down alarm and location system |
US5316008A (en) * | 1990-04-06 | 1994-05-31 | Casio Computer Co., Ltd. | Measurement of electrocardiographic wave and sphygmus |
GB9011887D0 (en) * | 1990-05-26 | 1990-07-18 | Le Fit Ltd | Pulse responsive device |
US5226425A (en) * | 1991-09-10 | 1993-07-13 | Ralin, Inc. | Portable ECG monitor/recorder |
JP3144030B2 (en) | 1992-02-24 | 2001-03-07 | 東陶機器株式会社 | Health management network system |
FI92139C (en) * | 1992-02-28 | 1994-10-10 | Matti Myllymaeki | Monitoring device for the health condition, which is attached to the wrist |
US5544649A (en) | 1992-03-25 | 1996-08-13 | Cardiomedix, Inc. | Ambulatory patient health monitoring techniques utilizing interactive visual communication |
WO1994015525A1 (en) * | 1993-01-06 | 1994-07-21 | Seiko Epson Corporation | Pulse wave processor |
US5416695A (en) | 1993-03-09 | 1995-05-16 | Metriplex, Inc. | Method and apparatus for alerting patients and medical personnel of emergency medical situations |
DE4329898A1 (en) | 1993-09-04 | 1995-04-06 | Marcus Dr Besson | Wireless medical diagnostic and monitoring device |
JP3241512B2 (en) * | 1993-11-29 | 2001-12-25 | 日本コーリン株式会社 | Biological information measurement device |
US5544661A (en) * | 1994-01-13 | 1996-08-13 | Charles L. Davis | Real time ambulatory patient monitor |
US5652570A (en) | 1994-05-19 | 1997-07-29 | Lepkofker; Robert | Individual location system |
US5807267A (en) * | 1994-06-01 | 1998-09-15 | Advanced Body Metrics Corporation | Heart pulse monitor |
FI943283A (en) | 1994-07-11 | 1996-01-12 | Polar Electro Oy | Data entry means |
US5462051A (en) | 1994-08-31 | 1995-10-31 | Colin Corporation | Medical communication system |
US5778882A (en) * | 1995-02-24 | 1998-07-14 | Brigham And Women's Hospital | Health monitoring system |
US6238338B1 (en) * | 1999-07-19 | 2001-05-29 | Altec, Inc. | Biosignal monitoring system and method |
SE9502430D0 (en) * | 1995-07-04 | 1995-07-04 | Pacesetter Ab | Device for varying the threshold detection level of a sensor |
US5730720A (en) | 1995-08-18 | 1998-03-24 | Ip Scientific, Inc. | Perfusion hyperthermia treatment system and method |
KR970020056A (en) | 1995-09-19 | 1997-05-28 | 노보루 아까사까 | Patient monitor device |
US5738104A (en) * | 1995-11-08 | 1998-04-14 | Salutron, Inc. | EKG based heart rate monitor |
FI960636A (en) | 1996-02-12 | 1997-08-13 | Nokia Mobile Phones Ltd | A procedure for monitoring the health of a patient |
US5801755A (en) | 1996-04-09 | 1998-09-01 | Echerer; Scott J. | Interactive communciation system for medical treatment of remotely located patients |
US5853005A (en) | 1996-05-02 | 1998-12-29 | The United States Of America As Represented By The Secretary Of The Army | Acoustic monitoring system |
US5899928A (en) | 1996-05-14 | 1999-05-04 | Pacesetter, Inc. | Descriptive transtelephonic pacing intervals for use by an emplantable pacemaker |
US6265978B1 (en) * | 1996-07-14 | 2001-07-24 | Atlas Researches, Ltd. | Method and apparatus for monitoring states of consciousness, drowsiness, distress, and performance |
IL118854A0 (en) | 1996-07-15 | 1996-10-31 | Atlas Dan | Personal micro-monitoring and alerting device for sleepiness |
US5877675A (en) | 1996-08-29 | 1999-03-02 | Jansys, Inc. | Wireless healthcare communication system |
US6364834B1 (en) | 1996-11-13 | 2002-04-02 | Criticare Systems, Inc. | Method and system for remotely monitoring multiple medical parameters in an integrated medical monitoring system |
US5771001A (en) | 1996-11-18 | 1998-06-23 | Cobb; Marlon J. | Personal alarm system |
US6198394B1 (en) * | 1996-12-05 | 2001-03-06 | Stephen C. Jacobsen | System for remote monitoring of personnel |
US5942979A (en) * | 1997-04-07 | 1999-08-24 | Luppino; Richard | On guard vehicle safety warning system |
US5865761A (en) | 1997-05-05 | 1999-02-02 | Colin Corporation | Apparatus for detecting blood pressure and electrocardiographic waveforms |
FI973386A (en) | 1997-07-25 | 1999-01-26 | Vaeaenaenen Mikko Kalervo | A method for analyzing and communicating health information |
US6471087B1 (en) * | 1997-07-31 | 2002-10-29 | Larry Shusterman | Remote patient monitoring system with garment and automated medication dispenser |
US6139494A (en) | 1997-10-15 | 2000-10-31 | Health Informatics Tools | Method and apparatus for an integrated clinical tele-informatics system |
US5971930A (en) * | 1997-10-17 | 1999-10-26 | Siemens Medical Systems, Inc. | Method and apparatus for removing artifact from physiological signals |
JP2001521804A (en) | 1997-10-31 | 2001-11-13 | アミラ メディカル | Collection of analyte concentration information and communication system |
WO1999042800A1 (en) * | 1998-02-20 | 1999-08-26 | Massachusetts Institute Of Technology | Finger touch sensors and virtual switch panels |
FI109843B (en) * | 1998-04-09 | 2002-10-15 | Ist Oy | Real estate automation control system controlled by human physiological signals |
US7112175B2 (en) * | 1998-05-26 | 2006-09-26 | Ineedmd.Com | Tele-diagnostic device |
US6224548B1 (en) * | 1998-05-26 | 2001-05-01 | Ineedmd.Com, Inc. | Tele-diagnostic device |
US6491647B1 (en) * | 1998-09-23 | 2002-12-10 | Active Signal Technologies, Inc. | Physiological sensing device |
US6306088B1 (en) * | 1998-10-03 | 2001-10-23 | Individual Monitoring Systems, Inc. | Ambulatory distributed recorders system for diagnosing medical disorders |
US6160478A (en) * | 1998-10-27 | 2000-12-12 | Sarcos Lc | Wireless health monitoring system |
US6398727B1 (en) * | 1998-12-23 | 2002-06-04 | Baxter International Inc. | Method and apparatus for providing patient care |
WO2000047108A1 (en) * | 1999-02-08 | 2000-08-17 | Medoc Ltd. | Ambulatory monitor |
JP4046883B2 (en) | 1999-02-09 | 2008-02-13 | 株式会社タニタ | Body fat scale and health management system |
US6385473B1 (en) * | 1999-04-15 | 2002-05-07 | Nexan Limited | Physiological sensor device |
US6494829B1 (en) * | 1999-04-15 | 2002-12-17 | Nexan Limited | Physiological sensor array |
AU6890400A (en) * | 1999-07-26 | 2001-02-13 | Joseph Charles Bok | System, apparatus, and method for telemetry and monitoring of desired targets |
WO2001016855A2 (en) * | 1999-08-13 | 2001-03-08 | Vitality Websystems, Inc. | Method and apparatus for establishing, maintaining, and improving an exercise, nutrition, or rehabilitation regime |
FI19991800A (en) | 1999-08-24 | 2001-02-25 | Sepponen Raimo Erik | Arrangements to provide expert service |
US6694180B1 (en) * | 1999-10-11 | 2004-02-17 | Peter V. Boesen | Wireless biopotential sensing device and method with capability of short-range radio frequency transmission and reception |
FI114282B (en) * | 1999-11-05 | 2004-09-30 | Polar Electro Oy | Method, Arrangement and Heart Rate Monitor for Heartbeat Detection |
DE19962700A1 (en) | 1999-12-23 | 2001-06-28 | Lre Technology Partner Gmbh | Blood pressure measuring device has pulse wave propagation time set based on ECG signal and signal from pressure sensor |
WO2001049169A1 (en) * | 2000-01-03 | 2001-07-12 | Sportbrain, Inc. | Personal data capture device and web posting system |
DE10005526A1 (en) | 2000-02-08 | 2001-08-30 | Klaschka Gmbh & Co | Device for monitoring the physiological functioning of a patient or animal in which physiological sensors are linked to a processor that transmits medical data via a mobile phone, enabling a patient to be more mobile |
US6893396B2 (en) * | 2000-03-01 | 2005-05-17 | I-Medik, Inc. | Wireless internet bio-telemetry monitoring system and interface |
DE10009882A1 (en) | 2000-03-01 | 2001-10-11 | Dietmar W Klaudtky | Mobile telecommunications terminal, in particular a mobile phone |
US6443890B1 (en) | 2000-03-01 | 2002-09-03 | I-Medik, Inc. | Wireless internet bio-telemetry monitoring system |
WO2001073541A1 (en) * | 2000-03-29 | 2001-10-04 | Sportbrain, Inc. | Method and apparatus for capturing personal data using a bar code scanner |
US6616613B1 (en) | 2000-04-27 | 2003-09-09 | Vitalsines International, Inc. | Physiological signal monitoring system |
MXPA06002836A (en) * | 2000-06-16 | 2006-06-14 | Bodymedia Inc | System for monitoring and managing body weight and other physiological conditions including iterative and personalized planning, intervention and reporting capability. |
DE60129964T2 (en) | 2000-06-22 | 2008-05-08 | Fridolin Voegeli | HEALTH MONITORING SYSTEM |
US6616647B1 (en) * | 2000-06-27 | 2003-09-09 | Kimberly-Clark Worldwide, Inc. | Machine direction manufactured pant |
WO2002017210A2 (en) | 2000-08-18 | 2002-02-28 | Cygnus, Inc. | Formulation and manipulation of databases of analyte and associated values |
EP1256875A1 (en) * | 2001-05-10 | 2002-11-13 | Nokia Corporation | Method and device for context dependent user input prediction |
US7044911B2 (en) * | 2001-06-29 | 2006-05-16 | Philometron, Inc. | Gateway platform for biological monitoring and delivery of therapeutic compounds |
US6840904B2 (en) * | 2001-10-11 | 2005-01-11 | Jason Goldberg | Medical monitoring device and system |
DE20119965U1 (en) | 2001-12-10 | 2002-05-29 | Amluck Inc | Electrocardiograph with the function of a blood pressure monitor |
ATE445354T1 (en) | 2001-12-10 | 2009-10-15 | Medic4All Ag | VISUAL MEDICAL MONITORING SYSTEM FOR A REMOTE PERSON |
US20030107487A1 (en) | 2001-12-10 | 2003-06-12 | Ronen Korman | Method and device for measuring physiological parameters at the wrist |
AU2003217253A1 (en) * | 2002-01-25 | 2003-09-02 | Intellipatch, Inc. | Evaluation of a patient and prediction of chronic symptoms |
US6783498B2 (en) * | 2002-03-26 | 2004-08-31 | Vivometrics, Inc. | Method and system for extracting cardiac parameters from plethysmographic signals |
CA2501732C (en) * | 2002-10-09 | 2013-07-30 | Bodymedia, Inc. | Method and apparatus for auto journaling of continuous or discrete body states utilizing physiological and/or contextual parameters |
AU2002952927A0 (en) | 2002-11-25 | 2002-12-12 | Vladimir Jankov | Combined wrist blood pressure and ecg monitor |
US20040204635A1 (en) * | 2003-04-10 | 2004-10-14 | Scharf Tom D. | Devices and methods for the annotation of physiological data with associated observational data |
TWI234449B (en) * | 2003-08-20 | 2005-06-21 | Kang-Ping Lin | A electrocardiogram measuring device and its method |
CA2538710A1 (en) * | 2003-09-12 | 2005-03-31 | Bodymedia, Inc. | Method and apparatus for measuring heart related parameters |
US6982930B1 (en) * | 2004-07-27 | 2006-01-03 | Chin-Yeh Hung | Wristwatch with the function of sensing heart pulses |
WO2006018833A2 (en) * | 2004-08-16 | 2006-02-23 | Tadiran Spectralink Ltd. | A wearable device, system and method for measuring a pulse while a user is in motion |
CN101193588A (en) * | 2005-03-21 | 2008-06-04 | 海尔思-斯玛特有限公司 | System for continuous blood pressure monitoring |
US20070265541A1 (en) * | 2006-05-15 | 2007-11-15 | Chin-Yeh Hung | MP3 player capable of transmitting pulse data |
-
2001
- 2001-12-10 US US10/006,357 patent/US20030107487A1/en not_active Abandoned
-
2002
- 2002-12-10 KR KR10-2004-7008912A patent/KR20040072648A/en not_active Application Discontinuation
- 2002-12-10 WO PCT/IL2002/000995 patent/WO2003050643A2/en active Application Filing
- 2002-12-10 US US10/497,169 patent/US7598878B2/en not_active Expired - Fee Related
- 2002-12-10 EP EP11163901A patent/EP2361550A3/en not_active Withdrawn
- 2002-12-10 AU AU2002358956A patent/AU2002358956A1/en not_active Abandoned
- 2002-12-10 CN CNA028280024A patent/CN1623175A/en active Pending
- 2002-12-10 IL IL16241402A patent/IL162414A0/en unknown
- 2002-12-10 EP EP11163908A patent/EP2361555A3/en not_active Withdrawn
- 2002-12-10 JP JP2003551635A patent/JP2005511223A/en active Pending
- 2002-12-10 EP EP02793300A patent/EP1459274A4/en not_active Withdrawn
-
2009
- 2009-10-01 US US12/571,747 patent/US20100049010A1/en not_active Abandoned
Cited By (169)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8265907B2 (en) | 1999-03-03 | 2012-09-11 | Card Guard Scientific Survival Ltd. | System and a method for physiological monitoring |
US9015008B2 (en) | 1999-03-03 | 2015-04-21 | Card Guard Scientific Survival Ltd. | System and a method for physiological monitoring |
US20100117835A1 (en) * | 1999-03-03 | 2010-05-13 | Reuven Nanikashvili | System and a method for physiological monitoring |
USRE41236E1 (en) | 2000-07-05 | 2010-04-20 | Seely Andrew J E | Method and apparatus for multiple patient parameter variability analysis and display |
US20050116820A1 (en) * | 2001-12-10 | 2005-06-02 | Rami Goldreich | Method and device for measuring physiological parameters at the wrist |
US7598878B2 (en) | 2001-12-10 | 2009-10-06 | Rami Goldreich | Method and device for measuring physiological parameters at the wrist |
US9636056B2 (en) | 2002-01-24 | 2017-05-02 | Masimo Corporation | Physiological trend monitor |
US20050083193A1 (en) * | 2002-01-24 | 2005-04-21 | Ammar Al-Ali | Parallel measurement alarm processor |
USRE49034E1 (en) | 2002-01-24 | 2022-04-19 | Masimo Corporation | Physiological trend monitor |
US6822564B2 (en) * | 2002-01-24 | 2004-11-23 | Masimo Corporation | Parallel measurement alarm processor |
US20030137423A1 (en) * | 2002-01-24 | 2003-07-24 | Ammar Al-Ali | Parallel measurement alarm processor |
US20140009283A1 (en) * | 2002-05-08 | 2014-01-09 | Resource Consortium Limited | Method and system for remotely monitoring a user |
US8952806B2 (en) * | 2002-05-08 | 2015-02-10 | Resource Consortium Limited | Method and system for remotely monitoring a user |
US20040027246A1 (en) * | 2002-08-09 | 2004-02-12 | S.I.E.M. S.R.L. | Portable device with sensors for signalling physiological data |
US8679011B2 (en) | 2002-09-03 | 2014-03-25 | Omni Medsci, Inc. | System and method for voice control of medical devices |
US7993108B2 (en) | 2002-10-09 | 2011-08-09 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US7922458B2 (en) | 2002-10-09 | 2011-04-12 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US8047812B2 (en) | 2002-10-09 | 2011-11-01 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US8047811B2 (en) | 2002-10-09 | 2011-11-01 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US8029250B2 (en) | 2002-10-09 | 2011-10-04 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US8029245B2 (en) | 2002-10-09 | 2011-10-04 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US7993109B2 (en) | 2002-10-09 | 2011-08-09 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
US8343093B2 (en) | 2002-10-09 | 2013-01-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7766864B2 (en) * | 2002-10-09 | 2010-08-03 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7727181B2 (en) | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7753873B2 (en) * | 2002-10-09 | 2010-07-13 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7753874B2 (en) * | 2002-10-09 | 2010-07-13 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7515044B2 (en) * | 2003-03-21 | 2009-04-07 | Welch Allyn, Inc. | Personal status physiologic monitor system and architecture and related monitoring methods |
US7515043B2 (en) * | 2003-03-21 | 2009-04-07 | Welch Allyn, Inc. | Personal status physiologic monitor system and architecture and related monitoring methods |
US20060238333A1 (en) * | 2003-03-21 | 2006-10-26 | Welch Allyn Protocol, Inc. | Personal status physiologic monitor system and architecture and related monitoring methods |
US20070069887A1 (en) * | 2003-03-21 | 2007-03-29 | Welch Allyn Protocol, Inc. | Personal status physiologic monitor system and architecture and related monitoring methods |
US20150327778A1 (en) * | 2003-04-23 | 2015-11-19 | Bonutti Research, Inc. | Monitoring apparatus and other devices |
US9763581B2 (en) | 2003-04-23 | 2017-09-19 | P Tech, Llc | Patient monitoring apparatus and method for orthosis and other devices |
US20140171809A1 (en) * | 2003-04-23 | 2014-06-19 | Peter M. Bonutti | Monitoring apparatus and other devices |
US8512246B2 (en) | 2003-04-28 | 2013-08-20 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems |
US7679407B2 (en) | 2003-04-28 | 2010-03-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems |
US8071028B2 (en) | 2003-06-12 | 2011-12-06 | Abbott Diabetes Care Inc. | Method and apparatus for providing power management in data communication systems |
US9109926B2 (en) | 2003-06-12 | 2015-08-18 | Abbott Diabetes Care Inc. | Method and apparatus for providing power management in data communication systems |
US8906307B2 (en) | 2003-06-12 | 2014-12-09 | Abbott Diabetes Care Inc. | Apparatus for providing power management in data communication systems |
US8273295B2 (en) | 2003-06-12 | 2012-09-25 | Abbott Diabetes Care Inc. | Apparatus for providing power management in data communication systems |
US20110279262A1 (en) * | 2003-10-30 | 2011-11-17 | Peter Lupoli | Method and system for storing, retrieving, and managing data for tags |
US20050171418A1 (en) * | 2004-01-08 | 2005-08-04 | Tah-Yeong Lin | Capsule endoscopy system |
US8290589B2 (en) | 2004-04-07 | 2012-10-16 | Cardiac Pacemakers, Inc. | System and method for RF transceiver duty cycling in an implantable medical device |
US20080114412A1 (en) * | 2004-04-07 | 2008-05-15 | Cardiac Pacemakers, Inc. | System and method for RF transceiver duty cycling in an implantable medical device |
EP1732643B1 (en) * | 2004-04-07 | 2013-02-27 | Cardiac Pacemakers, Inc. | System and method for rf transceiver duty cycling in an implantable medical device |
US8639339B2 (en) | 2004-04-07 | 2014-01-28 | Cardiac Pacemakers, Inc. | System and method for RF wake-up of implantable medical device |
US8358210B2 (en) | 2005-02-08 | 2013-01-22 | Abbott Diabetes Care Inc. | RF tag on test strips, test strip vials and boxes |
US8223021B2 (en) | 2005-02-08 | 2012-07-17 | Abbott Diabetes Care Inc. | RF tag on test strips, test strip vials and boxes |
US8115635B2 (en) | 2005-02-08 | 2012-02-14 | Abbott Diabetes Care Inc. | RF tag on test strips, test strip vials and boxes |
US20060229503A1 (en) * | 2005-02-08 | 2006-10-12 | Gunter Fluegel | Device for monitoring vital values of persons needing monitoring |
US8390455B2 (en) | 2005-02-08 | 2013-03-05 | Abbott Diabetes Care Inc. | RF tag on test strips, test strip vials and boxes |
US8542122B2 (en) | 2005-02-08 | 2013-09-24 | Abbott Diabetes Care Inc. | Glucose measurement device and methods using RFID |
US7996187B2 (en) | 2005-02-16 | 2011-08-09 | Card Guard Scientific Survival Ltd. | Method and system for health monitoring |
US20170172463A1 (en) * | 2005-03-11 | 2017-06-22 | Nrv-Wellness, Llc | Mobile wireless customizable health and condition monitor |
US20100016745A1 (en) * | 2005-03-11 | 2010-01-21 | Aframe Digital, Inc. | Mobile wireless customizable health and condition monitor |
US8378811B2 (en) * | 2005-03-11 | 2013-02-19 | Aframe Digital, Inc. | Mobile wireless customizable health and condition monitor |
US8029460B2 (en) | 2005-03-21 | 2011-10-04 | Abbott Diabetes Care Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
US8029459B2 (en) | 2005-03-21 | 2011-10-04 | Abbott Diabetes Care Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
US8343092B2 (en) | 2005-03-21 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
US10206611B2 (en) | 2005-05-17 | 2019-02-19 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US8089363B2 (en) | 2005-05-17 | 2012-01-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US9750440B2 (en) | 2005-05-17 | 2017-09-05 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US8471714B2 (en) | 2005-05-17 | 2013-06-25 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US7884729B2 (en) | 2005-05-17 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US8653977B2 (en) | 2005-05-17 | 2014-02-18 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US9332944B2 (en) | 2005-05-17 | 2016-05-10 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US8112138B2 (en) | 2005-06-03 | 2012-02-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US8574182B2 (en) | 2005-08-01 | 2013-11-05 | Collar ID, LLC | Restraint device and method of use |
US7330122B2 (en) * | 2005-08-10 | 2008-02-12 | Remotemdx, Inc. | Remote tracking and communication device |
US8031077B2 (en) | 2005-08-10 | 2011-10-04 | Securealert, Inc. | Remote tracking and communication device |
US20070063853A1 (en) * | 2005-08-10 | 2007-03-22 | Derrick Bruce G | Remote tracking and communication device |
US7804412B2 (en) | 2005-08-10 | 2010-09-28 | Securealert, Inc. | Remote tracking and communication device |
US7756561B2 (en) | 2005-09-30 | 2010-07-13 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US8638220B2 (en) | 2005-10-31 | 2014-01-28 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
US7948370B2 (en) | 2005-10-31 | 2011-05-24 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
US7583190B2 (en) * | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
WO2007058826A3 (en) * | 2005-11-14 | 2008-04-17 | Edwards Lifesciences Corp | Wireless communication system for pressure monitoring |
US20070112274A1 (en) * | 2005-11-14 | 2007-05-17 | Edwards Lifesciences Corporation | Wireless communication system for pressure monitoring |
US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device |
US20070204699A1 (en) * | 2006-03-02 | 2007-09-06 | General Electric Company | Remote strain measurement |
US8013736B2 (en) | 2006-07-14 | 2011-09-06 | Securealert, Inc. | Alarm and alarm management system for remote tracking devices |
US7936262B2 (en) | 2006-07-14 | 2011-05-03 | Securealert, Inc. | Remote tracking system with a dedicated monitoring center |
US8797210B2 (en) | 2006-07-14 | 2014-08-05 | Securealert, Inc. | Remote tracking device and a system and method for two-way voice communication between the device and a monitoring center |
US7737841B2 (en) | 2006-07-14 | 2010-06-15 | Remotemdx | Alarm and alarm management system for remote tracking devices |
US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US9064107B2 (en) | 2006-10-31 | 2015-06-23 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US11837358B2 (en) | 2006-10-31 | 2023-12-05 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US11508476B2 (en) | 2006-10-31 | 2022-11-22 | Abbott Diabetes Care, Inc. | Infusion devices and methods |
US11043300B2 (en) | 2006-10-31 | 2021-06-22 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US10007759B2 (en) | 2006-10-31 | 2018-06-26 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US20090157695A1 (en) * | 2007-08-10 | 2009-06-18 | Smiths Medical Md | Central Server for Medical Devices |
US8473306B2 (en) | 2007-10-03 | 2013-06-25 | Ottawa Hospital Research Institute | Method and apparatus for monitoring physiological parameter variability over time for one or more organs |
US20100261977A1 (en) * | 2007-10-03 | 2010-10-14 | Seely Andrew J E | Method and Apparatus for Monitoring Physiological Parameter Variability Over Time for One or More Organs |
US8924235B2 (en) | 2007-10-03 | 2014-12-30 | Ottawa Hospital Research Institute | Method and apparatus for monitoring physiological parameter variability over time for one or more organs |
US8232876B2 (en) | 2008-03-07 | 2012-07-31 | Securealert, Inc. | System and method for monitoring individuals using a beacon and intelligent remote tracking device |
US20110078253A1 (en) * | 2008-12-12 | 2011-03-31 | eVent Medical, Inc | System and method for communicating over a network with a medical device |
US8082312B2 (en) | 2008-12-12 | 2011-12-20 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US8560082B2 (en) | 2009-01-30 | 2013-10-15 | Abbott Diabetes Care Inc. | Computerized determination of insulin pump therapy parameters using real time and retrospective data processing |
US20100249541A1 (en) * | 2009-03-27 | 2010-09-30 | LifeWatch Corp. | Methods and Apparatus for Processing Physiological Data Acquired from an Ambulatory Physiological Monitoring Unit |
US8467972B2 (en) | 2009-04-28 | 2013-06-18 | Abbott Diabetes Care Inc. | Closed loop blood glucose control algorithm analysis |
US8798934B2 (en) | 2009-07-23 | 2014-08-05 | Abbott Diabetes Care Inc. | Real time management of data relating to physiological control of glucose levels |
US10872102B2 (en) | 2009-07-23 | 2020-12-22 | Abbott Diabetes Care Inc. | Real time management of data relating to physiological control of glucose levels |
US20110105919A1 (en) * | 2009-10-30 | 2011-05-05 | Mohammed Naji | Medical device |
WO2011053593A1 (en) * | 2009-10-30 | 2011-05-05 | Mohammed Naji | Medical device |
US20110219091A1 (en) * | 2010-01-19 | 2011-09-08 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US20110231504A1 (en) * | 2010-01-19 | 2011-09-22 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US20110231505A1 (en) * | 2010-01-19 | 2011-09-22 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US8060576B2 (en) | 2010-01-19 | 2011-11-15 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US8171094B2 (en) | 2010-01-19 | 2012-05-01 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US20110179123A1 (en) * | 2010-01-19 | 2011-07-21 | Event Medical, Inc. | System and method for communicating over a network with a medical device |
US9129504B2 (en) | 2010-04-07 | 2015-09-08 | Securealert, Inc. | Tracking device incorporating cuff with cut resistant materials |
US8514070B2 (en) | 2010-04-07 | 2013-08-20 | Securealert, Inc. | Tracking device incorporating enhanced security mounting strap |
US9833158B2 (en) | 2010-06-08 | 2017-12-05 | Alivecor, Inc. | Two electrode apparatus and methods for twelve lead ECG |
US9351654B2 (en) | 2010-06-08 | 2016-05-31 | Alivecor, Inc. | Two electrode apparatus and methods for twelve lead ECG |
US9649042B2 (en) | 2010-06-08 | 2017-05-16 | Alivecor, Inc. | Heart monitoring system usable with a smartphone or computer |
US11382554B2 (en) | 2010-06-08 | 2022-07-12 | Alivecor, Inc. | Heart monitoring system usable with a smartphone or computer |
ITPO20100009A1 (en) * | 2010-09-13 | 2012-03-14 | Daniele Faggi | DISTANCE-BASED ACQUISITION AND MONITORING SYSTEM VIA TELEMATIC NETWORKS OF BIOMETRIC DATA IN SECURITY AREA. |
US11883195B2 (en) | 2010-09-30 | 2024-01-30 | Fitbit, Inc. | Multimode sensor devices |
US10381109B2 (en) | 2010-09-30 | 2019-08-13 | Fitbit, Inc. | Multimode sensor devices |
US10216893B2 (en) | 2010-09-30 | 2019-02-26 | Fitbit, Inc. | Multimode sensor devices |
US9872087B2 (en) | 2010-10-19 | 2018-01-16 | Welch Allyn, Inc. | Platform for patient monitoring |
WO2013006680A1 (en) * | 2011-07-05 | 2013-01-10 | Collar ID, LLC | Apparatus and methods for sensing a parameter with a restraint device |
US20140320309A1 (en) * | 2011-07-14 | 2014-10-30 | Jinjing Zhang | Cardiac Electricity and Impedance Monitoring Mobile Network Terminal Device Having Function of Micro Current Release |
US9024781B2 (en) * | 2011-07-14 | 2015-05-05 | Jinjing Zhang | Cardiac electricity and impedance monitoring mobile network terminal device having function of micro current release |
CN102608426A (en) * | 2012-03-31 | 2012-07-25 | 上海鼎松信息技术有限公司 | Master controller and method applied to automatically detecting abnormal state of wrist strap |
US10178973B2 (en) | 2012-06-22 | 2019-01-15 | Fitbit, Inc. | Wearable heart rate monitor |
US9662053B2 (en) | 2012-06-22 | 2017-05-30 | Fitbit, Inc. | Physiological data collection |
US11096601B2 (en) | 2012-06-22 | 2021-08-24 | Fitbit, Inc. | Optical device for determining pulse rate |
US9226702B2 (en) * | 2012-10-12 | 2016-01-05 | Roche Diabetes Care, Inc. | Communication protocol improvement to recover data from a continuous glucose monitor |
US20140107449A1 (en) * | 2012-10-12 | 2014-04-17 | Roche Diagnostics Operations, Inc. | Communication protocol improvement to recover data from a continuous glucose monitor |
US9254095B2 (en) | 2012-11-08 | 2016-02-09 | Alivecor | Electrocardiogram signal detection |
US10478084B2 (en) | 2012-11-08 | 2019-11-19 | Alivecor, Inc. | Electrocardiogram signal detection |
US9019099B2 (en) * | 2012-11-12 | 2015-04-28 | Covidien Lp | Systems and methods for patient monitoring |
US20140132413A1 (en) * | 2012-11-12 | 2014-05-15 | Covidien Lp | Systems and methods for patient monitoring |
US9579062B2 (en) | 2013-01-07 | 2017-02-28 | Alivecor, Inc. | Methods and systems for electrode placement |
US9220430B2 (en) | 2013-01-07 | 2015-12-29 | Alivecor, Inc. | Methods and systems for electrode placement |
US11259707B2 (en) | 2013-01-15 | 2022-03-01 | Fitbit, Inc. | Methods, systems and devices for measuring heart rate |
US9254092B2 (en) | 2013-03-15 | 2016-02-09 | Alivecor, Inc. | Systems and methods for processing and analyzing medical data |
US10342495B2 (en) | 2013-05-17 | 2019-07-09 | Nokia Technologies Oy | Method and system for providing an early risk recognition monitoring |
US10512407B2 (en) | 2013-06-24 | 2019-12-24 | Fitbit, Inc. | Heart rate data collection |
US9681814B2 (en) | 2013-07-10 | 2017-06-20 | Alivecor, Inc. | Devices and methods for real-time denoising of electrocardiograms |
US9247911B2 (en) | 2013-07-10 | 2016-02-02 | Alivecor, Inc. | Devices and methods for real-time denoising of electrocardiograms |
US11090003B2 (en) * | 2013-09-09 | 2021-08-17 | Healthy.Io Ltd. | Systems for personal portable wireless vital signs scanner |
EP2851756A3 (en) * | 2013-09-18 | 2016-01-20 | Suzhou Lonshine Technologies Co. | Integrated smart watch |
US9572499B2 (en) | 2013-12-12 | 2017-02-21 | Alivecor, Inc. | Methods and systems for arrhythmia tracking and scoring |
US10159415B2 (en) | 2013-12-12 | 2018-12-25 | Alivecor, Inc. | Methods and systems for arrhythmia tracking and scoring |
US9420956B2 (en) | 2013-12-12 | 2016-08-23 | Alivecor, Inc. | Methods and systems for arrhythmia tracking and scoring |
ES2538040A1 (en) * | 2013-12-16 | 2015-06-16 | Ineuron Health Systems, S.L. | Device, system and method for the non-invasive measurement of physiological data (Machine-translation by Google Translate, not legally binding) |
WO2015139522A1 (en) * | 2014-03-21 | 2015-09-24 | 辛勤 | Wrist-type apparatus used for health monitoring |
US11622455B2 (en) | 2014-10-28 | 2023-04-04 | Samsung Electronics Co., Ltd. | Wearable electronic device |
EP3654140A3 (en) * | 2014-10-28 | 2020-08-19 | Samsung Electronics Co., Ltd. | Wearable electronic device |
CN104510452A (en) * | 2014-12-30 | 2015-04-15 | 江苏华阳电器有限公司 | Portable heart rhythm and body temperature real-time detector |
US10537250B2 (en) | 2015-05-13 | 2020-01-21 | Alivecor, Inc. | Discordance monitoring |
US9839363B2 (en) | 2015-05-13 | 2017-12-12 | Alivecor, Inc. | Discordance monitoring |
US9775548B2 (en) | 2015-05-28 | 2017-10-03 | Fitbit, Inc. | Heart rate sensor with high-aspect-ratio photodetector element |
CN104872942A (en) * | 2015-06-01 | 2015-09-02 | 深圳市浪尖设计有限公司 | Smart bracelet |
CN105005194A (en) * | 2015-07-28 | 2015-10-28 | 广东欧珀移动通信有限公司 | Prompting method and device and smart watch |
CN105261164A (en) * | 2015-10-23 | 2016-01-20 | 小米科技有限责任公司 | Message prompting method and apparatus |
US11206989B2 (en) | 2015-12-10 | 2021-12-28 | Fitbit, Inc. | Light field management in an optical biological parameter sensor |
US11317816B1 (en) | 2015-12-14 | 2022-05-03 | Fitbit, Inc. | Multi-wavelength pulse oximetry |
US10568525B1 (en) | 2015-12-14 | 2020-02-25 | Fitbit, Inc. | Multi-wavelength pulse oximetry |
US11666235B2 (en) | 2016-04-29 | 2023-06-06 | Fitbit, Inc. | In-canal heart rate monitoring apparatus |
US10433739B2 (en) | 2016-04-29 | 2019-10-08 | Fitbit, Inc. | Multi-channel photoplethysmography sensor |
US11633117B2 (en) | 2016-04-29 | 2023-04-25 | Fitbit, Inc. | Multi-channel photoplethysmography sensor |
CN106209150A (en) * | 2016-07-12 | 2016-12-07 | 陕西理工大学 | A kind of computer radio data collector |
US11779231B2 (en) | 2017-04-07 | 2023-10-10 | Fitbit, Inc. | Multiple source-detector pair photoplethysmography (PPG) sensor |
US11051706B1 (en) | 2017-04-07 | 2021-07-06 | Fitbit, Inc. | Multiple source-detector pair photoplethysmography (PPG) sensor |
US10353430B2 (en) | 2017-08-07 | 2019-07-16 | Samsung Electronics Co., Ltd. | Wearable device and electronic apparatus |
Also Published As
Publication number | Publication date |
---|---|
IL162414A0 (en) | 2005-11-20 |
US20050116820A1 (en) | 2005-06-02 |
EP1459274A4 (en) | 2009-02-25 |
WO2003050643A3 (en) | 2003-10-16 |
JP2005511223A (en) | 2005-04-28 |
EP1459274A2 (en) | 2004-09-22 |
WO2003050643A2 (en) | 2003-06-19 |
EP2361555A2 (en) | 2011-08-31 |
KR20040072648A (en) | 2004-08-18 |
US20100049010A1 (en) | 2010-02-25 |
AU2002358956A1 (en) | 2003-06-23 |
EP2361550A3 (en) | 2012-05-02 |
EP2361555A3 (en) | 2012-04-25 |
US7598878B2 (en) | 2009-10-06 |
CN1623175A (en) | 2005-06-01 |
EP2361550A2 (en) | 2011-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20030107487A1 (en) | Method and device for measuring physiological parameters at the wrist | |
US20080051667A1 (en) | Method And Device For Measuring Physiological Parameters At The Hand | |
US20210361245A1 (en) | System and method for reducing false alarms associated with vital-signs monitoring | |
US7761261B2 (en) | Portable wireless gateway for remote medical examination | |
US10709330B2 (en) | Ambulatory medical telemetry device having an audio indicator | |
US20050080322A1 (en) | Monitoring method and monitoring system for assessing physiological parameters of a subject | |
Lobodzinski et al. | New devices for very long-term ECG monitoring | |
US20050075542A1 (en) | System and method for automatic monitoring of the health of a user | |
US20060224072A1 (en) | Disposable extended wear heart monitor patch | |
US20090264714A1 (en) | Non-invasive vital sign monitoring method, apparatus and system | |
JP2005511223A5 (en) | ||
EP2471444A1 (en) | Wireless optical pulsimetry system for a healtcare environment | |
WO2008005016A1 (en) | Disposable extended wear heart monitor patch | |
KR20120008484U (en) | Removable bio signal detecting device for wristwatch | |
JP2012152374A (en) | Radio-optical pulsimeter system for medical environment | |
CN105011920A (en) | Medical monitoring system based on GSM | |
US20210076952A1 (en) | Compound physiological detection device | |
CN211187185U (en) | Combined type physiological detection device | |
KR101200462B1 (en) | U-health service system and method | |
JP3167116U (en) | Wireless optical pulse meter system for medical environment | |
JP2006263305A (en) | Non-healthy subject monitoring system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: MEDIC4ALL AG, SWITZERLAND Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:KORMAN, RONEN;COHEN, MOSHE;KORMAN, DORON;AND OTHERS;REEL/FRAME:012609/0556;SIGNING DATES FROM 20011230 TO 20020131 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |