Suche Bilder Maps Play YouTube News Gmail Drive Mehr »
Anmelden
Nutzer von Screenreadern: Klicke auf diesen Link, um die Bedienungshilfen zu aktivieren. Dieser Modus bietet die gleichen Grundfunktionen, funktioniert aber besser mit deinem Reader.

Patentsuche

  1. Erweiterte Patentsuche
VeröffentlichungsnummerUS20040098131 A1
PublikationstypAnmeldung
AnmeldenummerUS 10/713,837
Veröffentlichungsdatum20. Mai 2004
Eingetragen14. Nov. 2003
Prioritätsdatum22. Juli 1996
Auch veröffentlicht unterCA2202453A1, CA2202453C, DE69725932D1, DE69725932T2, EP0820740A1, EP0820740B1, EP1166725A2, EP1166725A3, EP1166725B1, US5674296, US5865846, US6001130, US6156067, USRE42480, USRE42576
Veröffentlichungsnummer10713837, 713837, US 2004/0098131 A1, US 2004/098131 A1, US 20040098131 A1, US 20040098131A1, US 2004098131 A1, US 2004098131A1, US-A1-20040098131, US-A1-2004098131, US2004/0098131A1, US2004/098131A1, US20040098131 A1, US20040098131A1, US2004098131 A1, US2004098131A1
ErfinderVincent Bryan, Alex Kunzler
Ursprünglich BevollmächtigterSdgi Holdings, Inc.
Zitat exportierenBiBTeX, EndNote, RefMan
Externe Links: USPTO, USPTO-Zuordnung, Espacenet
Human spinal disc prosthesis
US 20040098131 A1
Zusammenfassung
The invention relates to a spinal disc endoprosthesis. The endoprosthesis has a resilient body formed of one or more materials which may vary in stiffness from a relatively stiff exterior annular gasket portion to a relatively supple central nucleus portion. Concaval-convex elements at least partly surround that nucleus portion so as to retain the nucleus portion and gasket between adjacent vertebral bodies in a patient's spine. Assemblies of endoprosthetic discs, endoprosthetic vertebral bodies, and endoprosthetic longitudinal ligaments may be constructed. To implant this endoprosthesis assembly, information is obtained regarding the size, shape, and nature of a patient's damaged spine. Thereafter, one or more prosthetic vertebral bodies and disc units are constructed in conformity with that information. Finally, the completed and conformed vertebral body and disc assembly is implanted in the patient's spine.
Bilder(11)
Previous page
Next page
Ansprüche(20)
We claim:
1. A method of surgery comprising:
forming concave surfaces in endplates of confronting vertebral bodies; and
inserting between the formed concave surfaces an intervertebral disc endoprosthesis wherein the intervertebral disc endoprosthesis comprises:
L-shaped supports wherein each of the L-shaped support comprises an exterior convex surface adapted to mate with one of the formed concave surfaces; and
a resilient body interposed between the L-shaped supports.
2. The method of claim 1, further comprising affixing the L-shaped supports to the confronting vertebral bodies.
3. The method of claim 1, further comprising implanting at least one anchor in at least one of the confronting vertebral bodies.
4. The method of claim 3, wherein the implanting is located in an anterior surface of the at least one of the confronting vertebral bodies.
5. The method of claim 4, further comprising affixing a bone surface milling mechanism to the at least one anchor.
6. The method of claim 1 wherein the resilient body comprises a relative stiff portion and a relative supple portion.
7. A method of surgery comprising:
implanting at least one anchor in an anterior surface of at least one of confronting vertebral bodies;
forming concave surfaces in the endplates of the confronting vertebral bodies; and
inserting between the formed concave surfaces an intervertebral disc endoprosthesis comprising:
confronting supports, each support having an exterior convex surface adapted to mate with one of the formed concave surfaces; and
a resilient body interposed between the supports.
8. The method of claim 7, further comprising affixing a bone surface milling mechanism to the at least one anchor.
9. The method of claim 7, further comprising removing damaged disc material.
10. The method of claim 7 wherein the resilient body comprises a relative stiff portion and a relative supple portion.
11. A method of spinal surgery comprising:
forming mounting holes in one or more vertebral bodies of a patient's spine;
implanting at least one anchor into one of the mounting holes;
utilizing the at least one anchor to mount a bone mill on the patient's spine;
milling confronting bone surfaces on and in the patient's spine to a predetermined surface shape;
removing the bone mill; and
mounting an intervertebral disc endoprosthesis having a predetermined outer surface shape so that outer surfaces of the intervertebral disc endoprosthesis mate with the previously milled bone surfaces and are capable of motion relative to each other.
12. A method of endoprosthetic discectomy surgery comprising:
receiving information about the size, shape, and nature of a patient's involved natural spinal vertebral bodies and natural spinal vertebral discs from imaging devices;
removing at least the involved and damaged natural spinal disc material from the patient's spine;
implanting at least one anchor into a hole having a predetermined position in an anterior surface of at least one adjacent vertebral body;
forming concave surfaces in the adjacent vertebral bodies; and
implanting into the patient's spine, an intervertebral disc endoprosthesis comprising a resilient disc body and concaval-convex elements that at least partly surround and are capable of movement relative to the resilient disc body in the patient's spine.
13. The method of claim 12, further comprising affixing a bone surface milling mechanism to the at least one anchor.
14. The method of claim 12 wherein the concaval-convex elements are adjacent to the resilient body.
15. The method of claim 12 wherein the concaval-convex elements are in contact with the resilient body.
16. A method of surgery comprising:
implanting at least one anchor into a hole having a predetermined position in an anterior surface of at least one adjacent vertebral body;
affixing a bone surface milling mechanism to the at least one anchor;
forming concave surfaces in the endplates of the adjacent vertebral bodies; and
inserting between the formed concave surfaces an intervertebral disc endoprosthesis, comprising:
confronting concaval-convex supports, each support having an exterior convex surface adapted to mate with one of the formed concave surfaces; and
a resilient body between the concaval-convex supports.
17. The method of claim 14 wherein the concaval-convex supports are adjacent to the resilient body.
18. The method of claim 14 wherein the concaval-convex supports are in contact with the resilient body.
19. The method of claim 14 wherein the resilient body comprises a gasket portion and a nucleus portion.
20. A method of inserting a prosthesis in a disc space between two adjacent vertebral bodies, comprising:
implanting at least one anchor into a hole having a predetermined position in an anterior surface of at least one adjacent vertebral body;
affixing a bone surface milling mechanism to the at least one anchor;
forming at least a portion of a hemispherical cavity in an endplate of one of the vertebral bodies, the endplate have a remaining surface surrounding the cavity; and
inserting an endoprosthesis into the disc space and the cavity, the endoprosthesis including at least one support having an exterior convex surface adapted to mate with the cavity, and a body interposed between the at least one support and the second vertebral body, wherein the at least one support is movable relative to the body.
Beschreibung
    CROSS-REFERENCE
  • [0001]
    This application is a continuation of U.S. patent application Ser. No. 09/776,394 entitled “HUMAN SPINAL DISC PROSTHESIS” filed on Feb. 2, 2001, which is a reissue application of the U.S. Pat. No. 5,865,846 entitled “HUMAN SPINAL DISC PROSTHESIS” filed on May 15, 1997, each of which is hereby incorporated by reference.
  • BACKGROUND
  • [0002]
    This invention relates generally to human prostheses, and especially to spinal column vertebral disc prostheses. The invention also relates to surgical procedures for preparing the patient to receive a vertebral disc endoprosthesis, and for implanting that endoprosthesis in the patient's spine.
  • [0003]
    The herniation of a spinal disc and the often resultant symptoms of intractable pain, weakness, sensory loss, incontinence and progressive arthritis are among the most common of debilitating processes affecting mankind. If a patient's condition does not improve after conservative treatment, and if clear physical evidence of nerve root or spinal cord compression is apparent, and if correlating radiographic studies (i.e., MRI or CT imaging or myelography) confirm the condition, surgical removal of the herniated disc may be indicated. The process of discectomy—as the name implies—involves the simple removal of the disc without attempt to replace or repair the malfunctioning unit. In the United States in 1985, over 250,000 such operations were performed in the lumbar spine and in the cervical spine.
  • [0004]
    Statistics suggest that present surgical techniques are likely to result in short-term relief, but will not prevent the progressive deterioration of the patient's condition in the long run. Through better pre-operative procedures and diagnostic studies, long-term patient results have improved somewhat. But it has become clear that unless the removed disc is replaced or the spine is otherwise properly supported, further degeneration of the patient's condition will almost certainly occur.
  • [0005]
    In the mid-1950's and 60's, Cloward and Smith & Robinson popularized anterior surgical approaches to the cervical spine for the treatment of cervical degenerative disc disease and related disorders of the vertebrae, spinal cord and nerve root; these surgeries involved disc removal followed by interbody fusion with a bone graft. It was noted by Robinson (Robinson, R. A.: The Results of Anterior Interbody Fusion of the Cervical Spine, J. Bone Joint Surg., 440A: 1569-1586, 1962) that after surgical fusion, osteophyte (bone spur) reabsorption at the fused segment might take place. However, it has become increasingly apparent that unfused vertebral segments at the levels above and below the fused segment degenerate at accelerated rates as a direct result of this fusion. This has led some surgeons to perform discectomy alone, without fusion, by a posterior approach in the neck of some patients. However, as has occurred in surgeries involving the lower back where discectomy without fusion is more common as the initial treatment for disc herniation syndromes, progressive degeneration at the level of disc excision is the rule rather than the exception. Premature degenerative disc disease at the level above and below the excised disc can and does occur.
  • [0006]
    Spine surgery occasionally involves fusion of the spine segments. In addition to the problems created by disc herniation, traumatic, malignant, infectious and degenerative syndromes of the spine can be treated by fusion. Other procedures can include bone grafts and heavy duty metallic rods, hooks, plates and screws being appended to the patient's anatomy; often they are rigidly and internally fixed. None provide for a patient's return to near-normal functioning. Though these procedures may solve a short-term problem, they can cause other, longer term, problems.
  • [0007]
    A number of attempts have been made to solve some of the problems described above by providing a patient with spinal disc prostheses, or artificial discs of one sort or another. For example, Steffee, U.S. Pat. No. 5,031,437, describes a spinal disc prosthesis having upper and lower rigid flat plates and a flat elastomeric core sandwiched between the plates. Frey et al., U.S. Pat. Nos. 4,917,704 and 4,955,908, disclose intervertebral prostheses, but the prostheses are described as solid bodies.
  • [0008]
    U.S. Pat. Nos. 4,911,718 and 5,171,281 disclose resilient disc spacers, but no inter-connective or containing planes or like elements are suggested, and sealing the entire unit is not taught.
  • [0009]
    It is the primary aim of the present invention to provide a vertebral disc endoprosthesis which will perform effectively and efficiently within a patient's spine over a long period of time, and which will not encourage degeneration of or cause damage to adjacent natural disc parts.
  • [0010]
    It is another object to provide a vertebral disc endoprosthesis which does not require pins or other common mechanical hinge elements, yet which permits natural motion of the prosthetic parts and the adjacent natural anatomy.
  • [0011]
    It is a related objective to provide a new vertebral disc endoprosthesis surgical procedure which will decrease post-operative recovery time and inhibit post-operative disc, vertebral body and spinal joint degeneration.
  • [0012]
    It is yet another object to provide a method of installing the endoprosthesis so as to accurately mate the endoprosthesis with an adjacent specifically formed bone surface. An associated object is to provide an endoprosthesis which will encourage bone attachment to, and growth upon, adjacent outer surfaces of the endoprosthesis.
  • [0013]
    Yet another object is to provide a vertebral endoprosthesis in which the parts are non-oncogenic.
  • [0014]
    Still another object is to provide a vertebral disc endoprosthesis having a resilient element to accommodate shocks and other forces applied to the spine.
  • [0015]
    Another object is to provide a highly effective vertebral endoprosthesis which includes several disc endoprostheses and one or more prosthetic vertebral bodies. A related object is to provide these elements in a pre-assembled array for implantation in a patient.
  • SUMMARY OF THE INVENTION
  • [0016]
    To accomplish these objects, the invention comprises a resilient body formed of a material varying in stiffness from a relatively stiff exterior portion to a relatively supple central portion. A concaval-convex means at least partly surrounds that resilient body so as to retain the resilient body between adjacent vertebral bodies of a patient's spine. If medical considerations so indicate, several disc endoprostheses can be combined with one or more endoprosthetic vertebral bodies in an entire assembly.
  • [0017]
    To implant this endoprosthesis assembly, information is obtained regarding the size, shape, and nature of a patient's damaged natural spinal discs. If one or more of the patient's vertebral bodies also require replacement, information about those bodies is also obtained. Thereafter, one or more prosthetic disc units and interposed prosthetic vertebral body units are constructed and preassembled in conformity with that information. Finally, the completed and conformed prosthetic disc and vertebral body assembly is implanted in the patient's spine.
  • [0018]
    Other objects and advantages of the invention will become apparent upon reading the following detailed description and upon reference to the drawings. Throughout the drawings, like reference numerals refer to like parts.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0019]
    [0019]FIG. 1 is a fragmentary vertical view of a portion of a human spine in which is installed a novel vertebral disc endoprosthesis embodying the present invention;
  • [0020]
    [0020]FIG. 2 is a fragmentary side elevational view similar to FIG. 1 showing the elements of a patient's spine and having a novel vertebral disc endoprosthesis embodying the present invention installed therein;
  • [0021]
    [0021]FIG. 3 is a sectional view taken substantially in the plane of line 3-3 in FIG. 1;
  • [0022]
    [0022]FIG. 4 is an exploded view of the novel vertebral disc endoprosthesis;
  • [0023]
    [0023]FIG. 5 is a vertical fragmentary view of a patient's spine similar to FIG. 1, but showing a series of novel disc endoprosthesis units installed in the spine and interconnected to one another;
  • [0024]
    [0024]FIG. 6 is a fragmentary sectional view of a patient's spine similar to FIG. 3 and taken along line 6-6 in FIG. 5, but showing a natural upper vertebral body, and upper endoprosthetic disc; an adjacent endoprosthetic vertebral body; a second or lower endoprosthetic disc; and a second or lower natural vertebral body; p FIG. 7 is a sectional view taken substantially in the plane of line 7-7 of FIG. 6;
  • [0025]
    [0025]FIG. 8 is a fragmentary side elevational view of the assembly shown in FIG. 6; and
  • [0026]
    [0026]FIG. 9 is a fragment vertical view, similar to FIG. 1, of a portion of a human spine in which is installed a variant form of the novel vertebral disc endoprosthesis the variant form having a prosthetic longitudinal ligament;
  • [0027]
    [0027]FIG. 10 is a sectional view taken substantially in the plane of line 10-10 in FIG. 9;
  • [0028]
    [0028]FIG. 11 is a top view of a retainer means for use with a vertebral disc endoprosthesis;
  • [0029]
    [0029]FIG. 12 is a sectional view taken substantially in the plane of line 12-12 of FIG. 11;
  • [0030]
    [0030]FIG. 13 is a side view of a vertebral disc endoprosthesis having a groove for receiving the retainer means; and
  • [0031]
    [0031]FIG. 14 is a cross-sectional view of the retainer means in use.
  • DETAILED DESCRIPTION
  • [0032]
    While the invention will be described in connection with a preferred embodiment and procedure, it will be understood that it is not intended to limit the invention to this embodiment or procedure. On the contrary, it is intended to cover all alternatives, modifications, and equivalents as may be included within the spirit and scope of the invention as defined by the appended claims.
  • [0033]
    Turning more specifically to FIGS. 1-3, a portion of a human spine 10 is shown. The illustrated spine 10 has been subjected to a discectomy surgical process. To discourage degeneration of or damage to the natural vertebral bodies 12 and 14 and their respective facet joints, in accordance with the invention, a vertebral disc endoprosthesis 18 is affixed between the adjacent natural vertebral bodies 12 and 14. Here this vertebral disc endoprosthesis 18 comprises a resilient disc body 20 having a relatively stiff annular gasket exterior portion 22 and a relatively supple nuclear central portion 24. The annular gasket 22 can be formed from a suitable biocompatible elastomer of approximately 90 durometer hardness and the nuclear central portion 24 can be formed from a softer biocompatible elastomeric polymer of approximately 30 durometer hardness.
  • [0034]
    Concaval-convex means 30 surround the resilient body 20 to retain the resilient body 20 between the adjacent natural vertebral bodies 12, 14 in a patient's spine 10. To this end, as shown in FIG. 3, the concaval-convex means 30 comprise two generally L-shaped supports 32 and 34. The supports 32, 34 each have confronting first concaval-convex legs 42, 44, each leg being of relatively constant cross-sectional thickness. Each leg 42, 44 has an outer convex surface 52, 54 for engaging the adjacent bone of the natural vertebral bodies 12, 14. Corresponding inner concave surfaces 62, 64 in confronting array retain the resilient body 20 in its illustrated compressive force shock-absorbing position. These supports 32 and 34 can undergo principle movement away from one another, but only limited secondary translational, rotational and distractional motion will occur. Each support 32, 34 has a second wing or leg 72, 74 extending generally perpendicularly to the first legs 42, 44 respectively, and adapted for affixation to the adjacent bone structure. To carry out aspects of the invention described below, this affixation is effectively accomplished by cannulated screw devices 82, 84 which may be of a biodegradable type manufactured by Zimmer of Largo, Fla. Each device 82, 84 comprises a screw 92, 94; and a screw anchor 102, 104 adapted to threadably receive the screw extends radially into and seats within the bone structure 12, 14 as especially shown in FIG. 3.
  • [0035]
    To discourage and prohibit migration of fluids between the endoprosthesis 18 and adjacent parts of the anatomy, a seal member 110 is attached to the supports 32, 34 so as to surround the resilient body 20 comprised of the gasket 22 and nucleus 24, in accordance with another aspect of the invention. Here, this seal member 110 comprises a flexible sheet material having a multiplicity of pores. Preferably, the pores are from about 5 microns to about 60 microns in size. A flexible, strong polymer sheet material from which this seal is formed can be a Kevlar-like material, or it can be Goretex-like material, or other appropriate biocompatible material, such as polyether, polyurethane, or polycarbonate urethane membranes, can be used. Kevlar material is offered by the E.I. DuPont de Nemours Company of Wilmington, Del. and Goretex material is offered by the W.T. Gore Company of Flagstaff and Phoenix, Ariz. Known sealing material can be applied to the flexible sheet material so as to render the flexible sheet material substantially impervious to the passage of any fluid. A watertight seal is perfected when the seal 110 is glued or otherwise affixed to the legs 42, 44 and mediate portions of the legs 72, 74 as suggested in FIGS. 1-3.
  • [0036]
    In an alternative embodiment, the watertight seal between the endoprosthesis 18 and adjacent parts of the anatomy can be provided by developing a groove 402 completely encircling the periphery of each of the legs 42, 44. Only one of the grooves is shown in FIG. 13. In this embodiment, the seal member 410 is provided with a beaded edge 412 for each groove. Additionally, a retaining band 415 is provided for each groove to retain the seal member 410 in grooves 402. The retaining bands 415 can be in the form of a biocompatible monofilament wire of, for example, stainless steel or titanium, a synthetic polymer cable or a braided wire cable. As shown in FIG. 11, each retaining band is crimped anteriorly by a crimping sleeve 420. Of course, more than one crimping sleeve may be used, if necessary. Although one sealing arrangement consisting of the groove, beaded edge and retaining band is shown in FIG. 14, it should be understood that the sealing arrangement on the concaval-convex leg of the other support is identical in design and function.
  • [0037]
    In use, the seal member 410 is placed about the concaval-convex means 30. The retaining bands 415 are then placed adjacent to the respective groove 402 and crimped anteriorly, thereby fitting the bands into the grooves. Each beaded edge 412 prevents the slipping of the seal member underneath the retaining band. Thus, the retaining band, the groove and the beaded edge all cooperate to provide a water-tight seal to prevent the migration of fluids between the endoprosthesis 18 and adjacent parts of the anatomy. Glue can also be used to affix the seal member to the concaval-convex means 30 as a supplemental means for perfecting the seal.
  • [0038]
    In accordance with another aspect of the invention, the supports 32, 34 are formed of a biocompatible metal which may contain chromium cobalt or titanium. Surface roughening or titanium beading 112, 114 on the exterior surfaces 52, 54 of legs 42, 44 encourages positive bonding between the adjacent bone and the convex surfaces 52, 54.
  • [0039]
    As suggested in FIGS. 9 and 10, a prosthetic longitudinal ligament 250 can be connected between the screws 92, 94 to limit motions between elements of the spine 10 in the area where the endoprosthesis 18 is implanted. This strap 250 may be made of the Kevlar-like material or the Goretex-like material described above, or it may be made of any other strong biocompatible material.
  • [0040]
    In accordance with another aspect of the invention, multiple endoprosthetic disc units can be placed in series with a straddling interlock appendage providing stability and fixation as shown in FIG. 5. Entire portions of a patient's spine can be replaced by a series of interconnected endoprosthetic vertebral bodies and endoprosthetic disc units. FIGS. 6-8 show an upper natural vertebral body unit 312 to which an upper endoprosthetic body 308 has been attached. A lower natural vertebral body 314 has attached, at its upper end, an endoprosthetic disc unit 318. Between these endoprosthetic disc units 308 and 318 is an endoprosthetic vertebral body 320. As suggested by FIG. 7, the endoprosthetic vertebral body 320 need not be irregularly shaped in cross sectional aspect; rather, manufacturing processes may suggest that it have a circular cross-sectional shape. As show in FIGS. 6 and 8, this endoprosthetic vertebral body 320 comprises a titanium element 321, to which are attached the preformed upper and lower endoprosthetic vertebral body upper and lower concaval-convex elements 322, 324. Each concaval-convex element 322, 324 is attached to the prosthetic vertebral body 320, as shown in FIG. 7, by extending set screws 330 through the titanium vertebral body 321 into a stem-like projection 331 extending from each of the concaval-convex elements 322, 324. A hole 360 in the body 320 accommodates the stem-like projections 331 of the concaval-convex elements 322 and 324. The stem-like projection 331 of the concaval-convex elements 322 and 324 is used only in conjunction with a prosthetic vertebral body implant construction 320.
  • [0041]
    An ear 340 is affixed, as by weldments 341, to a leg 342 extending from a concaval-convex element 322 as illustrated in FIGS. 6 and 8. An anchor 352 can be threaded into the endoprosthetic vertebral body 320, and a screw 362 can be turned into the anchor 352 so as to rigidly assemble the leg 342 to a leg 354 extending from the lower endoprosthetic disc unit 318.
  • [0042]
    The upper disc endoprosthesis 308, the endoprosthetic vertebral body 320, and the lower disc endoprosthesis 318 can all be assembled and interconnected as a unit before implantation in a patient's body when indicated.
  • [0043]
    As also suggested in FIG. 6, the annular corners 372, 374 of natural vertebral bodies 312, 314 each can extend irregularly radially outwardly of the adjacent disc endoprosthesis 308, 318. However, the corners 382B, 384B of the prosthetic vertebral body 320 do not generally extend significantly outside those disc units 308, 318, thus discouraging vertebral body engagement with and consequent abrasion or other damage to adjacent portions of the patient's natural anatomy. Preferably the endoprosthetic vertebral body 320 is not exactly right cylindrical in shape, but is rather slightly biconical; that is, the endoprosthetic vertebral body 320 has a waist 390 of minimum radius R at an axial medial point as suggested in FIG. 6.
  • [0044]
    According to yet another aspect of the invention, novel surgical procedures permit effective and permanent installation of the endoprosthetic vertebral body 320 and associated parts. First, a surgeon or medical technician develops information about the size, shape and nature of a patient's damaged vertebral body or bodies from radiographs, CT and/or MRI scans, noting specifically the anterior-posterior and lateral dimensions of the end plate of each involved vertebral body and the vertical height of the anterior aspect of each involved vertebral and/or proximate vertebral body and vertical height of the mid portion of involved and proximate relatively normal intervertebral disc spaces. This information is transmitted by telephone, computer datalink or documentary transport to a specialized laboratory. That laboratory constructs one or more prosthetic assemblies of the sort shown in FIG. 6 in conformity with the received information and this disclosure. Each of the assemblies can include a prosthetic vertebral body 321, and at each body end is a prosthetic disc 308, 318. Each prosthetic disc unit comprises, in turn, the concaval-convex elements 30; the resilient body 20 interposed between the concaval-convex elements; and the seal unit 110 secured around the interior legs and resilient body. Thereafter, the completed and conformed assembly is implanted in the patient's spine 10.
  • [0045]
    When the unit or units have been received and the patient properly prepared, the damaged natural spinal disc or discs and vertebral body or bodies are removed and the adjacent spinal bone surfaces are milled or otherwise formed to provide concave surfaces to receive the confronting convex surfaces 52, 54. Thereafter, the disc units and vertebral body are installed in the patient's spine.
  • [0046]
    To accurately locate the concaval-convex surfaces in the patient's spine, holes 382A, 384A (FIG. 3) are precisely located and then formed in the bone structure using a measuring instrument centered in the evacuated natural intravertebral disc space. These holes are then tapped to form female threads therein. When the threads have been formed, the anchors 102, 104 are implanted in the respective tapped holes, thereby creating reference points located precisely with respect to the patient's spine. After the holes have been formed and the anchors 102, 104 implanted, a bone surface milling jig (not shown) is affixed to the anchors 102, 104 and the desired concave surfaces of predetermined shape are formed on the inferior and superior surfaces of the opposing vertebral bodies using one of a selection of predetermined milling head or bit sizes. Thereafter, the bone milling jig is removed and the concaval-convex elements 52, 54 identical in shape to the milled surfaces 112, 114 are inserted between the distracted milled vertebral bodies 12, 14. The distraction device is then moved. The concaval-convex structures are then attached by the same anchors 102, 104 to the bone, thus insuring a precise and stable mate between the bone surfaces and the convex surfaces 52, 54.
  • [0047]
    If necessary, a damaged implanted nucleus and/or gasket 24 can be removed and replaced. This can be accomplished by slitting the seal 110; removing the annular gasket 24 and damaged nucleus 22, and replacing them with new, undamaged elements. Thereafter, the seal 110 can be re-established by suturing or gluing closed the slit seal.
Patentzitate
Zitiertes PatentEingetragen Veröffentlichungsdatum Antragsteller Titel
US2677369 *26. März 19524. Mai 1954Fred L KnowlesApparatus for treatment of the spinal column
US3875595 *15. Apr. 19748. Apr. 1975Froning Edward CIntervertebral disc prosthesis and instruments for locating same
US3876728 *16. März 19738. Apr. 1975Hodogaya Chemical Co LtdUrethane resins from tolylene diisocyanate distillation residues active hydrogen containing compounds and vinyl monomers
US4023572 *5. Aug. 197517. Mai 1977Hanfried WeigandMilling tool for preparing a joint socket in the prosthetic replacement of a joint
US4116200 *1. Okt. 197626. Sept. 1978Aesculap-Werke Aktiengesellschaft Vormals Jetter & ScheererMilling tool for surgical purposes
US4309777 *13. Nov. 198012. Jan. 1982Patil Arun AArtificial intervertebral disc
US4349921 *16. Juni 198021. Sept. 1982Kuntz J DavidIntervertebral disc prosthesis
US4599086 *7. Juni 19858. Juli 1986Doty James RSpine stabilization device and method
US4645507 *3. Sept. 198524. Febr. 1987Gmt Gesellschaft Fur Medizinische Technik MbhProsthesis
US4743256 *22. Jan. 198710. Mai 1988Brantigan John WSurgical prosthetic implant facilitating vertebral interbody fusion and method
US4757983 *20. Aug. 198619. Juli 1988Charles D. Ray, Ltd.Head and chin for face-down operations
US4759766 *9. Sept. 198726. Juli 1988Humboldt-Universitaet Zu BerlinIntervertebral disc endoprosthesis
US4759769 *22. Juni 198726. Juli 1988Health & Research Services Inc.Artificial spinal disc
US4766328 *26. Mai 198723. Aug. 1988System-General CorporationProgrammable pulse generator
US4777942 *24. Sept. 198718. Okt. 1988Sulzer Brothers LimitedBone milling instrument
US4800639 *12. Juni 198731. Jan. 1989Sulzer Brothers LimitedMethod of making a metal bone implant
US4834757 *28. März 198830. Mai 1989Brantigan John WProsthetic implant
US4863476 *28. Aug. 19875. Sept. 1989Shepperd John A NSpinal implant
US4863477 *12. Mai 19875. Sept. 1989Monson Gary LSynthetic intervertebral disc prosthesis
US4874389 *7. Dez. 198717. Okt. 1989Downey Ernest LReplacement disc
US4904260 *25. Juli 198827. Febr. 1990Cedar Surgical, Inc.Prosthetic disc containing therapeutic material
US4904261 *4. Aug. 198827. Febr. 1990A. W. Showell (Surgicraft) LimitedSpinal implants
US4908032 *2. März 198813. März 1990Waldemar Link Gmbh & Co.Reconstruction prosthesis
US4908036 *31. Mai 198813. März 1990Waldemar Link Gmbh & Co.Endoprosthesis
US4911718 *10. Juni 198827. März 1990University Of Medicine & Dentistry Of N.J.Functional and biocompatible intervertebral disc spacer
US4917704 *8. Juni 198817. Apr. 1990Sulzer Brothers LimitedIntervertebral prosthesis
US4932969 *17. Dez. 198712. Juni 1990Sulzer Brothers LimitedJoint endoprosthesis
US4932975 *16. Okt. 198912. Juni 1990Vanderbilt UniversityVertebral prosthesis
US4946378 *22. Nov. 19887. Aug. 1990Asahi Kogaku Kogyo Kabushiki KaishaArtificial intervertebral disc
US4955908 *8. Juni 198811. Sept. 1990Sulzer Brothers LimitedMetallic intervertebral prosthesis
US4997432 *14. März 19895. März 1991Waldemar Link Gmbh & Co.Surgical instrument set
US5002576 *6. Juni 198926. März 1991Mecron Medizinische Produkte GmbhIntervertebral disk endoprosthesis
US5015247 *13. Juni 198814. Mai 1991Michelson Gary KThreaded spinal implant
US5035716 *10. Mai 199030. Juli 1991Downey Ernest LReplacement disc
US5047055 *21. Dez. 199010. Sept. 1991Pfizer Hospital Products Group, Inc.Hydrogel intervertebral disc nucleus
US5059193 *19. Apr. 199022. Okt. 1991Spine-Tech, Inc.Expandable spinal implant and surgical method
US5059194 *12. Febr. 199022. Okt. 1991Michelson Gary KCervical distractor
US5080662 *27. Nov. 198914. Jan. 1992Paul Kamaljit SSpinal stereotaxic device and method
US5084048 *29. Juni 199028. Jan. 1992Sulzer Brothers LimitedImplant for vertebrae with spinal stabilizer
US5108438 *7. Mai 199028. Apr. 1992Regen CorporationProsthetic intervertebral disc
US5122130 *25. Okt. 199016. Juni 1992Waldemar Link Gmbh & Co.Forceps for inserting intervertebral device
US5123926 *22. Febr. 199123. Juni 1992Madhavan PisharodiArtificial spinal prosthesis
US5176708 *28. Febr. 19915. Jan. 1993Sulzer Brothers LimitedProsthetic implant
US5192326 *9. Sept. 19919. März 1993Pfizer Hospital Products Group, Inc.Hydrogel bead intervertebral disc nucleus
US5192327 *22. März 19919. März 1993Brantigan John WSurgical prosthetic implant for vertebrae
US5234431 *2. Apr. 199210. Aug. 1993Waldemar Link Gmbh & Co.Bone plate arrangement
US5236460 *10. Okt. 199117. Aug. 1993Midas Rex Pneumatic Tools, Inc.Vertebral body prosthesis
US5246458 *7. Okt. 199221. Sept. 1993Graham Donald VArtificial disk
US5314478 *26. Apr. 199124. Mai 1994Kyocera CorporationArtificial bone connection prosthesis
US5320644 *30. Juli 199214. Juni 1994Sulzer Brothers LimitedIntervertebral disk prosthesis
US5383933 *26. Nov. 199224. Jan. 1995Waldemar Link Gmbh & Co.Endoprosthesis
US5401269 *10. März 199328. März 1995Waldemar Link Gmbh & Co.Intervertebral disc endoprosthesis
US5403314 *5. Febr. 19934. Apr. 1995Acromed CorporationApparatus for retaining spinal elements in a desired spatial relationship
US5425772 *20. Sept. 199320. Juni 1995Brantigan; John W.Prosthetic implant for intervertebral spinal fusion
US5425773 *5. Apr. 199420. Juni 1995Danek Medical, Inc.Intervertebral disk arthroplasty device
US5443514 *1. Okt. 199322. Aug. 1995Acromed CorporationMethod for using spinal implants
US5456719 *18. Sept. 199210. Okt. 1995Waldemar Link Gmbh & CoEndoprosthesis with a prosthesis part made of viscoelastic synthetic resin
US5458638 *6. Nov. 199217. Okt. 1995Spine-Tech, Inc.Non-threaded spinal implant
US5458642 *18. Jan. 199417. Okt. 1995Beer; John C.Synthetic intervertebral disc
US5484437 *10. Juni 199316. Jan. 1996Michelson; Gary K.Apparatus and method of inserting spinal implants
US5487307 *10. Febr. 199430. Jan. 1996Kalman Floor Company, Inc.Method and apparatus for testing concrete expansion
US5489308 *1. Sept. 19946. Febr. 1996Spine-Tech, Inc.Spinal implant
US5496318 *18. Aug. 19935. März 1996Advanced Spine Fixation Systems, Inc.Interspinous segmental spine fixation device
US5507816 *1. Dez. 199216. Apr. 1996Customflex LimitedSpinal vertebrae implants
US5514180 *14. Jan. 19947. Mai 1996Heggeness; Michael H.Prosthetic intervertebral devices
US5527315 *18. Okt. 199418. Juni 1996Jbs S.A.Spinal osteosynthesis rod with three branches
US5534028 *20. Apr. 19939. Juli 1996Howmedica, Inc.Hydrogel intervertebral disc nucleus with diminished lateral bulging
US5534029 *1. Dez. 19939. Juli 1996Yumiko ShimaArticulated vertebral body spacer
US5534090 *20. Dez. 19849. Juli 1996The United States Of America As Represented By The Secretary Of The Air ForceDosimeter capsule indicating service life of a rocket motor
US5545229 *28. Juli 199313. Aug. 1996University Of Medicine And Dentistry Of NjFunctional and biocompatible intervertebral disc spacer containing elastomeric material of varying hardness
US5549679 *1. März 199527. Aug. 1996Kuslich; Stephen D.Expandable fabric implant for stabilizing the spinal motion segment
US5556431 *9. Aug. 199417. Sept. 1996B+E,Uml U+Ee Ttner-Janz; KarinIntervertebral disc endoprosthesis
US5562738 *12. Jan. 19958. Okt. 1996Danek Medical, Inc.Intervertebral disk arthroplasty device
US5593409 *17. Febr. 199514. Jan. 1997Sofamor Danek Group, Inc.Interbody spinal fusion implants
US5645598 *15. Apr. 19968. Juli 1997Smith & Nephew, Inc.Spinal fusion device with porous material
US5720748 *7. Juni 199524. Febr. 1998Spine-Tech, Inc.Spinal stabilization surgical apparatus
US5722977 *24. Jan. 19963. März 1998Danek Medical, Inc.Method and means for anterior lumbar exact cut with quadrilateral osteotome and precision guide/spacer
US5741253 *29. Okt. 199221. Apr. 1998Michelson; Gary KarlinMethod for inserting spinal implants
US5782830 *10. Juli 199621. Juli 1998Sdgi Holdings, Inc.Implant insertion device
US5782832 *1. Okt. 199621. Juli 1998Surgical Dynamics, Inc.Spinal fusion implant and method of insertion thereof
US5797909 *7. Juni 199525. Aug. 1998Michelson; Gary KarlinApparatus for inserting spinal implants
US5865848 *12. Sept. 19972. Febr. 1999Artifex, Ltd.Dynamic intervertebral spacer and method of use
US5885300 *31. März 199723. März 1999Asahi Kogaku Kogyo Kabushiki KaishaGuide apparatus of intervertebral implant
US5888226 *12. Nov. 199730. März 1999Rogozinski; ChaimIntervertebral prosthetic disc
US5928284 *9. Juli 199827. Juli 1999Mehdizadeh; Hamid M.Disc replacement prosthesis
US5947971 *21. Nov. 19967. Sept. 1999Sulzer Spine-Tech Inc.Spinal stabilization surgical apparatus
US6022376 *16. März 19988. Febr. 2000Raymedica, Inc.Percutaneous prosthetic spinal disc nucleus and method of manufacture
US6059790 *16. Juli 19989. Mai 2000Sulzer Spine-Tech Inc.Apparatus and method for spinal stabilization
US6059829 *8. März 19959. Mai 2000SyntheseIntervertebral implant
US6063121 *29. Juli 199816. Mai 2000Xavier; RaviVertebral body prosthesis
US6066174 *17. Juli 199823. Mai 2000Sdgi Holdings, Inc.Implant insertion device
US6080155 *27. Febr. 199527. Juni 2000Michelson; Gary KarlinMethod of inserting and preloading spinal implants
US6083228 *9. Juni 19984. Juli 2000Michelson; Gary K.Device and method for preparing a space between adjacent vertebrae to receive an insert
US6086595 *29. Aug. 199711. Juli 2000Sulzer Spine-Tech Inc.Apparatus and method for spinal stabilization
US6096038 *7. Juni 19951. Aug. 2000Michelson; Gary KarlinApparatus for inserting spinal implants
US6179874 *23. Apr. 199930. Jan. 2001Cauthen Research Group, Inc.Articulating spinal implant
US6228022 *28. Okt. 19988. Mai 2001Sdgi Holdings, Inc.Methods and instruments for spinal surgery
US6228026 *13. Aug. 19998. Mai 2001Rultract, Inc.Surgical support apparatus with splined coupling, cross bar support and head-to-toe extension for surgical retractor apparatus
US6231609 *10. Febr. 199915. Mai 2001Hamid M. MehdizadehDisc replacement prosthesis
Referenziert von
Zitiert von PatentEingetragen Veröffentlichungsdatum Antragsteller Titel
US696023225. Apr. 20031. Nov. 2005Blackstone Medical, Inc.Artificial intervertebral disc
US7338525 *30. Apr. 20034. März 2008Ferree Bret AMethods and apparatus for preventing the migration of intradiscal devices
US7556651 *7. Jan. 20057. Juli 2009Warsaw Orthopedic, Inc.Posterior spinal device and method
US765504527. Juli 20062. Febr. 2010Aesculap Implant Systems, LlcArtificial intervertebral disc
US766622615. Aug. 200623. Febr. 2010Benvenue Medical, Inc.Spinal tissue distraction devices
US766622715. Aug. 200623. Febr. 2010Benvenue Medical, Inc.Devices for limiting the movement of material introduced between layers of spinal tissue
US767037415. Aug. 20062. März 2010Benvenue Medical, Inc.Methods of distracting tissue layers of the human spine
US767037515. Aug. 20062. März 2010Benvenue Medical, Inc.Methods for limiting the movement of material introduced between layers of spinal tissue
US773175430. Aug. 20068. Juni 2010Spinalmotion, Inc.Intervertebral prosthesis
US775394117. Sept. 200413. Juli 2010Anulex Technologies, Inc.Devices and methods for annular repair of intervertebral discs
US7758649 *4. Aug. 200620. Juli 2010Integrity Intellect Inc.Reversibly deformable implant
US776307524. Febr. 200627. Juli 2010Theken Spine, LlcArtificial disc prosthesis
US776307624. Febr. 200627. Juli 2010Theken Spine, LlcArtificial disc prosthesis
US776696627. Juli 20063. Aug. 2010Aesculap Implant Systems, LlcArtificial intervertebral disc
US77714782. Apr. 200410. Aug. 2010Theken Spine, LlcArtificial disc prosthesis
US777148024. Febr. 200610. Aug. 2010Theken Spine, LlcArtificial disc prosthesis
US778536815. Aug. 200631. Aug. 2010Benvenue Medical, Inc.Spinal tissue distraction devices
US7803189 *29. Sept. 200628. Sept. 2010Spinal Kinetics, Inc.Prosthetic facet and facet joint replacement device
US780693524. Febr. 20065. Okt. 2010Theken Spine, LlcArtificial disc prosthesis
US781132630. Jan. 200612. Okt. 2010Warsaw Orthopedic Inc.Posterior joint replacement device
US783240919. Okt. 200716. Nov. 2010Aesculap Implant Systems, LlcMethod of inserting an artificial intervertebral disc
US790592220. Dez. 200615. März 2011Zimmer Spine, Inc.Surgical implant suitable for replacement of an intervertebral disc
US790592325. Mai 200715. März 2011Anulex Technologies, Inc.Devices and methods for annular repair of intervertebral discs
US792737413. Nov. 200619. Apr. 2011Synergy Disc Replacement, Inc.Artificial spinal disc
US795539115. Febr. 20107. Juni 2011Benvenue Medical, Inc.Methods for limiting the movement of material introduced between layers of spinal tissue
US796399315. Febr. 201021. Juni 2011Benvenue Medical, Inc.Methods of distracting tissue layers of the human spine
US796786415. Febr. 201028. Juni 2011Benvenue Medical, Inc.Spinal tissue distraction devices
US796786515. Febr. 201028. Juni 2011Benvenue Medical, Inc.Devices for limiting the movement of material introduced between layers of spinal tissue
US800283428. Apr. 200923. Aug. 2011Spinalmotion, Inc.Intervertebral prosthetic disc with metallic core
US8029569 *14. Nov. 20074. Okt. 2011International Spinal Innovations, LlcImplantable spinal disk
US805754415. Aug. 200615. Nov. 2011Benvenue Medical, Inc.Methods of distracting tissue layers of the human spine
US806237128. Apr. 200922. Nov. 2011Spinalmotion, Inc.Intervertebral prosthetic disc with metallic core
US80837974. Febr. 200527. Dez. 2011Spinalmotion, Inc.Intervertebral prosthetic disc with shock absorption
US809042811. Nov. 20093. Jan. 2012Spinalmotion, Inc.Spinal midline indicator
US809253815. Apr. 200810. Jan. 2012Spinalmotion, Inc.Intervertebral prosthetic disc
US810097430. Juni 200524. Jan. 2012Synergy Disc Replacement, Inc.Artificial spinal disc
US817290421. Sept. 20068. Mai 2012Synergy Disc Replacement, Inc.Artificial spinal disc
US82064477. März 200826. Juni 2012Spinalmotion, Inc.Methods and apparatus for intervertebral disc prosthesis insertion
US820644916. Juli 200926. Juni 2012Spinalmotion, Inc.Artificial intervertebral disc placement system
US826273230. Mai 200811. Sept. 2012Spinalmotion, Inc.Intervertebral prosthesis
US826273521. Juli 201111. Sept. 2012International Spinal Innovations, LlcImplantable spinal disk
US836677325. Jan. 20085. Febr. 2013Benvenue Medical, Inc.Apparatus and method for treating bone
US83721502. Aug. 201012. Febr. 2013Warsaw Orthpedic, Inc.Spinal device and method
US83987129. Nov. 201119. März 2013Spinalmotion, Inc.Intervertebral prosthetic disc with shock absorption
US8409287 *21. Mai 20102. Apr. 2013Warsaw Orthopedic, Inc.Intervertebral prosthetic systems, devices, and associated methods
US844469512. Mai 200921. Mai 2013Spinalmotion, Inc.Prosthetic disc for intervertebral insertion
US845461721. Febr. 20084. Juni 2013Benvenue Medical, Inc.Devices for treating the spine
US845469813. Febr. 20084. Juni 2013Spinalmotion, Inc.Prosthetic disc for intervertebral insertion
US84861474. Febr. 200816. Juli 2013Spinalmotion, Inc.Posterior spinal device and method
US850663115. Sept. 201013. Aug. 2013Spinalmotion, Inc.Customized intervertebral prosthetic disc with shock absorption
US853532716. März 201017. Sept. 2013Benvenue Medical, Inc.Delivery apparatus for use with implantable medical devices
US855697815. Nov. 201115. Okt. 2013Benvenue Medical, Inc.Devices and methods for treating the vertebral body
US859158321. Febr. 200826. Nov. 2013Benvenue Medical, Inc.Devices for treating the spine
US863680521. Mai 201228. Jan. 2014Spinalmotion, Inc.Artificial intervertebral disc placement system
US868503521. Juli 20051. Apr. 2014Spinalmotion, Inc.Intervertebral prosthesis placement instrument
US869674915. Juli 200415. Apr. 2014Blackstone Medical, Inc.Artificial intervertebral disc
US873451912. Apr. 200727. Mai 2014Spinalmotion, Inc.Posterior spinal device and method
US875844122. Okt. 200824. Juni 2014Spinalmotion, Inc.Vertebral body replacement and method for spanning a space formed upon removal of a vertebral body
US87648339. März 20091. Juli 2014Spinalmotion, Inc.Artificial intervertebral disc with lower height
US877135614. Sept. 20128. Juli 2014Spinalmotion, Inc.Intervertebral prosthetic disc
US879537523. Juli 20095. Aug. 2014Resspond Spinal SystemsModular nucleus pulposus prosthesis
US880178716. Juni 201112. Aug. 2014Benvenue Medical, Inc.Methods of distracting tissue layers of the human spine
US880179222. Juli 201012. Aug. 2014Spinalmotion, Inc.Posterio spinal device and method
US880837625. März 200919. Aug. 2014Benvenue Medical, Inc.Intravertebral implants
US884572925. Nov. 200930. Sept. 2014Simplify Medical, Inc.Prosthetic disc for intervertebral insertion
US884573016. Juli 200930. Sept. 2014Simplify Medical, Inc.Posterior prosthetic intervertebral disc
US886483216. Aug. 200721. Okt. 2014Hh Spinal LlcPosterior total joint replacement
US888283618. Dez. 201211. Nov. 2014Benvenue Medical, Inc.Apparatus and method for treating bone
US888885215. Juni 200918. Nov. 2014Hh Spinal LlcSpinal athroplasty device and method
US896160926. Sept. 201324. Febr. 2015Benvenue Medical, Inc.Devices for distracting tissue layers of the human spine
US896840824. Apr. 20133. März 2015Benvenue Medical, Inc.Devices for treating the spine
US897453130. Dez. 200910. März 2015Simplify Medical, Inc.Methods and apparatus for intervertebral disc prosthesis insertion
US89745338. Jan. 201410. März 2015Simplify Medical, Inc.Prosthetic disc for intervertebral insertion
US897992916. Juni 201117. März 2015Benvenue Medical, Inc.Spinal tissue distraction devices
US901154417. Aug. 201021. Apr. 2015Simplify Medical, Inc.Polyaryletherketone artificial intervertebral disc
US90340387. Apr. 200919. Mai 2015Spinalmotion, Inc.Motion limiting insert for an artificial intervertebral disc
US904433629. Mai 20122. Juni 2015International Spinal Innovations, LlcImplantable spinal disk
US904433812. März 20132. Juni 2015Benvenue Medical, Inc.Spinal tissue distraction devices
US906680820. Febr. 200930. Juni 2015Benvenue Medical, Inc.Method of interdigitating flowable material with bone tissue
US9066809 *15. Mai 200930. Juni 2015Globus Medical Inc.Method for inserting and positioning an artificial disc
US91077623. Nov. 201118. Aug. 2015Spinalmotion, Inc.Intervertebral prosthetic disc with metallic core
US92206031. Juli 200929. Dez. 2015Simplify Medical, Inc.Limited motion prosthetic intervertebral disc
US925932621. Nov. 201416. Febr. 2016Benvenue Medical, Inc.Spinal tissue distraction devices
US93268668. Nov. 20133. Mai 2016Benvenue Medical, Inc.Devices for treating the spine
US935184625. Aug. 201431. Mai 2016Simplify Medical, Inc.Posterior prosthetic intervertebral disc
US93643386. März 201314. Juni 2016Resspond Spinal SystemsModular nucleus pulposus prosthesis
US940274524. Nov. 20092. Aug. 2016Simplify Medical, Inc.Intervertebral prosthesis placement instrument
US9433511 *11. Aug. 20146. Sept. 2016Titan Spine, LlcInterbody spinal implant having a roughened surface topography
US94397747. Jan. 201113. Sept. 2016Simplify Medical Pty LtdIntervertebral prosthetic disc
US943977522. Mai 201413. Sept. 2016Simplify Medical Pty LtdArtificial intervertebral disc with lower height
US955491712. Juli 201331. Jan. 2017Simplify Medical Pty LtdCustomized intervertebral prosthetic disc with shock absorption
US96427124. Febr. 20159. Mai 2017Benvenue Medical, Inc.Methods for treating the spine
US965574110. Mai 201623. Mai 2017Simplify Medical Pty LtdProsthetic disc for intervertebral insertion
US966887811. Aug. 20166. Juni 2017Simplify Medical Pty LtdArtificial intervertebral disc with lower height
US96873552. Dez. 201627. Juni 2017Simplify Medical Pty LtdCustomized intervertebral prosthetic disc with shock absorption
US978896319. Okt. 201517. Okt. 2017DePuy Synthes Products, Inc.In-situ formed intervertebral fusion device and method
US97889651. Mai 201717. Okt. 2017Simplify Medical Pty LtdProsthetic disc for intervertebral insertion
US978897411. Jan. 201617. Okt. 2017Benvenue Medical, Inc.Spinal tissue distraction devices
US980172925. März 201531. Okt. 2017DePuy Synthes Products, Inc.In-situ formed intervertebral fusion device and method
US98083516. Okt. 20157. Nov. 2017DePuy Synthes Products, Inc.In-situ formed intervertebral fusion device and method
US20030204260 *30. Apr. 200330. Okt. 2003Ferree Bret A.Methods and apparatus for preventing the migration of intradiscal devices
US20040034423 *25. Apr. 200319. Febr. 2004Matthew LyonsArtificial intervertebral disc
US20040267369 *15. Juli 200430. Dez. 2004Matthew LyonsArtificial intervertebral disc
US20050033438 *29. Juni 200410. Febr. 2005Robert SchultzIntervertebral implant
US20050043803 *6. Juli 200424. Febr. 2005Robert SchultzIntervertebral implant
US20050060036 *6. Juli 200417. März 2005Robert SchultzSpinal column implant
US20050080487 *29. Juni 200414. Apr. 2005Robert SchultzIntervertebral implant
US20050143824 *15. Juni 200430. Juni 2005Marc RichelsophArtificial intervertebral disc
US20050154466 *7. Jan. 200514. Juli 2005Sdgi Holdings, Inc.Posterior spinal device and method
US20060009541 *9. Juli 200412. Jan. 2006Yih-Fang ChenSaturant for friction material containing friction modifying layer
US20060030857 *6. Aug. 20049. Febr. 2006Spinalmotion, Inc.Methods and apparatus for intervertebral disc prosthesis insertion
US20060142860 *24. Febr. 200629. Juni 2006Theken Disc, LlcArtificial disc prosthesis
US20060149377 *24. Febr. 20066. Juli 2006Theken Disc, LlcArtificial disc prosthesis
US20060235523 *19. Apr. 200519. Okt. 2006Sdgi Holdings, Inc.Implant having a sheath with a motion-limiting attribute
US20060235525 *19. Apr. 200519. Okt. 2006Sdgi Holdings, Inc.Composite structure for biomedical implants
US20060259146 *24. Febr. 200616. Nov. 2006Theken Disc, LlcArtificial disc prosthesis
US20060265071 *27. Juli 200623. Nov. 2006Marc RichelsophArtificial intervertebral disc
US20060265072 *27. Juli 200623. Nov. 2006Marc RichelsophArtificial intervertebral disc
US20070016190 *14. Juli 200518. Jan. 2007Medical Device Concepts LlcDynamic spinal stabilization system
US20070016204 *14. Juli 200518. Jan. 2007Medical Device Concepts Llc.Spinal buttress device and method
US20070055272 *15. Aug. 20068. März 2007Laurent SchallerSpinal Tissue Distraction Devices
US20070061011 *30. Aug. 200615. März 2007Spinalmotion, Inc.Intervertebral Prosthesis
US20070088441 *21. Sept. 200619. Apr. 2007Synergy Disc Replacement, Inc.Artificial Spinal Disc
US20070118218 *22. Nov. 200524. Mai 2007Hooper David MFacet joint implant and procedure
US20070123986 *15. Aug. 200631. Mai 2007Laurent SchallerMethods of Distracting Tissue Layers of the Human Spine
US20070168035 *29. Sept. 200619. Juli 2007Koske Nicholas CProsthetic facet and facet joint replacement device
US20070191945 *30. Jan. 200616. Aug. 2007Sdgi Holdings, Inc.Posterior joint replacement device
US20080027547 *27. Juli 200631. Jan. 2008Warsaw Orthopedic Inc.Prosthetic device for spinal joint reconstruction
US20080033575 *4. Aug. 20067. Febr. 2008Christopher WalshReversibly deformable implant
US20080045968 *18. Aug. 200621. Febr. 2008Warsaw Orthopedic, Inc.Instruments and Methods for Spinal Surgery
US20080133013 *30. Juni 20055. Juni 2008Synergy Disc Replacement, Inc.Artificial Spinal Disc
US20080183295 *14. Nov. 200731. Juli 2008Joseph AferzonImplantable spinal disk
US20080228277 *31. Okt. 200718. Sept. 2008Spinalmotion, Inc.Intervertebral prosthesis
US20080234687 *21. Febr. 200825. Sept. 2008Laurent SchallerDevices for treating the spine
US20080268056 *26. Apr. 200730. Okt. 2008Abhijeet JoshiInjectable copolymer hydrogel useful for repairing vertebral compression fractures
US20080269897 *26. Apr. 200730. Okt. 2008Abhijeet JoshiImplantable device and methods for repairing articulating joints for using the same
US20080294259 *31. Okt. 200727. Nov. 2008Spinalmotion, Inc.Intervertebral prosthesis
US20080300685 *16. Aug. 20074. Dez. 2008Warsaw Orthopedic, Inc.Posterior Total Joint Replacement
US20090069894 *13. Nov. 200612. März 2009Synergy Disc Replacement, Inc.Artificial Spinal Disc
US20090254183 *15. Juni 20098. Okt. 2009Warsaw Orthopedic, Inc.Spinal Arthroplasty Device and Method
US20090297603 *29. Mai 20083. Dez. 2009Abhijeet JoshiInterspinous dynamic stabilization system with anisotropic hydrogels
US20100023128 *23. Juli 200928. Jan. 2010Malberg Marc IModular nucleus pulposus prosthesis
US20100179419 *25. März 201015. Juli 2010Spinalmotion, Inc.Intervertebral Prosthesis
US20100292799 *15. Mai 200918. Nov. 2010Noah HansellMethod for Inserting and Positioning an Artificial Disc
US20110288645 *21. Mai 201024. Nov. 2011Warsaw Orthopedic, Inc.Intervertebral prosthetic systems, devices, and associated methods
US20110313556 *18. Apr. 201122. Dez. 2011Sten HolmMethod and arrangement at implants preferably for a human intervertebral and such implant
US20150289986 *21. Nov. 201315. Okt. 2015K2M, Inc.Flanged endplate for an intervertebral disc prosthesis and intervertebral disc prosthesis incorporating same
EP2327376A230. Juni 20051. Juni 2011Synergy Disc Replacement Inc.Artificial spinal disc
EP2641571A130. Juni 200525. Sept. 2013Synergy Disc Replacement Inc.Artificial spinal disc
WO2008103781A3 *21. Febr. 200820. Nov. 2008Benvenue Medical IncDevices for treating the spine
WO2010011849A1 *23. Juli 200928. Jan. 2010Malberg Marc IModular nucleus pulposus prosthesis