US20040176818A1 - Modular implantable medical device - Google Patents
Modular implantable medical device Download PDFInfo
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- US20040176818A1 US20040176818A1 US10/731,869 US73186903A US2004176818A1 US 20040176818 A1 US20040176818 A1 US 20040176818A1 US 73186903 A US73186903 A US 73186903A US 2004176818 A1 US2004176818 A1 US 2004176818A1
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- medical device
- implantable medical
- module
- overmold
- modules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/37514—Brain implants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/37518—Anchoring of the implants, e.g. fixation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/3752—Details of casing-lead connections
- A61N1/3754—Feedthroughs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/3758—Packaging of the components within the casing
Definitions
- the invention relates to medical devices, and more particularly, to implantable medical devices that deliver therapy to and/or monitor a patient.
- implantable medical devices may include a variety of electrical and/or mechanical components.
- an IMD includes a rigid housing that houses all of its components, which are generally fragile, to protect the components from forces to which they would otherwise be exposed when implanted within the human body.
- IMD housings are typically hermetically sealed.
- Many IMD housings are fabricated from Titanium because of its desirable rigidity and biocompatibility.
- an IMD is typically implanted within the abdomen, upper pectoral region, or subclavicular region of a patient.
- Leads or catheters must be used in order to deliver therapy or monitor a physiological parameter at a location of the body other than where the IMD is implanted.
- Implantation and positioning of leads and catheters can be difficult and time-consuming from the perspective of a surgeon, particularly where the IMD is located a significant distance from the treatment or monitoring site.
- the increased surgical time, increased surgical trauma, and increased amount of implanted material associated with the use of leads and catheters can increase the risk to the patient of complications associated with the implantation of an IMD.
- the invention is directed to an implantable medical device that includes a plurality of separately housed and flexibly interconnected modules.
- One of the modules is a control module that includes control electronics within a first housing.
- the control electronics control the functioning of the implantable medical device, and may include a processor.
- a second module may be a power source module that includes a power source within a second housing.
- the power source provides power to the first module, e.g., to the control electronics.
- the power source may be a rechargeable power source, such as a rechargeable battery or a capacitor.
- the implantable medical device is configured for implantation on the cranium of a patient.
- the implantable medical device may comprise a neurostimulator, and the control module may include therapy delivery circuitry for delivery of stimulation to the brain of a patient.
- the implantable medical device may include a lead connection module formed within the overmold to receive a lead or lead extension.
- the invention is directed to an implantable medical device that includes a first module and a second module.
- the first module includes control electronics within a first housing.
- the second module includes a power source that provides power to the first module housed within a second housing.
- the implantable medical device further includes an interconnect member that flexibly couples the first and second modules.
- the invention is directed to an implantable medical device that includes a first module and a second module.
- the first module includes control electronics housed within a first housing, and the second module that includes a power source that provides power to the first module housed within a second housing.
- the implantable medical device further includes a hermetic interconnect member that flexibly couples the first and second modules.
- the interconnect member is flexible in a plurality of directions and allows the first and second modules to have a plurality of degrees of freedom of movement relative to each other.
- FIG. 4 is top-view diagram illustrating a recharge module of the modular implantable medical device of FIG. 1.
- FIG. 5 is a block diagram illustrating a control module of the modular implantable medical device of FIG. 1.
- FIG. 7 is a block diagram illustrating a power source module of the modular implantable medical device of FIG. 6B.
- FIGS. 10, 11A, 11 B and 12 are conceptual diagrams illustrating other example modular implantable medical devices.
- FIGS. 14A and 14B are top-view diagrams illustrating other modular implantable medical devices.
- the flexibility of the interconnection between modules of IMD 10 may allow multiples degrees of freedom of movement between the modules, which in turn may allow the implantable medical device to conform to such areas, and in particular embodiments, to conform to surfaces within patient 14 such as the surface of cranium 12 .
- Holes 22 A and 22 B are drilled through cranium 12 , and leads 16 are inserted through holes 22 and into the brain of patient 14 . Caps may be placed over holes 22 as is known in the art. Leads 16 are connected to modular IMD 10 , either directly or via a lead extension, and modular IMD 10 is placed at least partially within a pocket formed using a hand or a tool beneath the scalp behind holes 22 .
- Modular IMD 10 may alternatively be implanted within a pectoral region or the abdomen of patient 14 to act as a diaphragmatic pacer, or to provide any of the monitoring and therapy delivery functions known in the art to be associated with cardiac pacemakers. Further, modular IMD 10 may be implanted in the upper buttock region and deliver spinal cord, urological or gastrological stimulation therapy, or may be configured to be implanted within the periphery, e.g., limbs, of patient 14 for delivery of stimulation to the muscles and/or peripheral nervous system of patient 14 . As is the case with cranium 12 , the modularity of IMD 10 may enable implantation at some of these example locations for which implantation of conventional IMDs is generally deemed undesirable.
- Housings 36 , 38 and 40 may have any shape, including the round, coin shape and rectangular shapes with rounded edges illustrated in FIG. 3. Further, one or more surfaces of one or more of housings 36 , 38 and 40 may be concave along at least one axis, and preferably two axes. Further details regarding the concavity of housings 36 , 38 and 40 may be found in a commonly-assigned U.S. patent application entitled “CONCAVITY OF AN IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-336US01/P-11800.00.
- Interconnect member 44 is flexible in a plurality of directions to provide modules 30 and 32 with multiple degrees of freedom of motion with respect to each other.
- interconnect member 44 provides at least three degrees of motion, and the degrees of motion provided include rotational motion. Further details regarding the configuration and/or construction of interconnect member 44 to provide such flexibility may be found in a commonly-assigned U.S. patent application entitled “COUPLING MODULE OF MODULAR IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-331US01/P-11796.00.
- modular IMD 10 includes an overmold 48 , which may be flexible.
- overmold 48 at least partially encapsulates each of housings 36 , 38 and 40 .
- Overmold 48 integrates modules 30 , 32 and 34 into a desired form factor, but, where flexible, allows relative intermodule motion.
- overmold 48 incorporates mechanical features to restrict intermodule motion to certain directions or within certain ranges.
- Overmold 48 may be made from silicone, and is some embodiments may be made from two or more materials of differing flexibility, such as silicone and a polyurethane.
- An exemplary polyurethane for this purpose is Tecothane®, which is commercially available from Hermedics Polymer Products, Wilmington, Mass. Use of the term “overmold” herein is not intend to limit the invention to embodiments in which overmold 48 is a molded structure.
- Overmold 48 may be a molded structure, or may be a structure formed by any process.
- FIGS. 3 and 6A illustrate substantially triangular configurations of modules 30 , 32 and 34 within modular IMDs 10 and 80 , respectively.
- overmolds 48 and 82 of IMDs 10 and 80 have substantially triangular shapes.
- Substantially triangular configurations of modules 30 , 32 and 34 and substantially triangularly shaped overmolds such as overmolds 48 and 82 may be preferred for some implantations, such as that described with reference to FIG. 2, in order to reduce the depth of the pocket formed under the scalp of patient 14 . Reduced pocket depth may allow for easier explant of modular IMDs 10 and 80 in the event explant is required.
- other configurations are possible, such as the substantially linear configuration of modules 30 , 32 and 34 within modular IMD 90 illustrated FIG. 6B.
- power source module 32 includes circuitry to control the recharging and discharging of the power source instead of, or in addition to power management circuit 70 within control module 30 .
- FIGS. 9A and 9B are top-view diagrams illustrating another example modular IMD 120 .
- recharge module 34 is not encapsulated by overmold 122 , but is instead tethered to overmold 122 by a flexible tether member 124 .
- Flexible tether member 124 is made of a flexible material, such as silicone, to allow substantial movement of recharge module 34 relative to other modules 30 and 32 as illustrated in FIG. 9B.
- flexible tether member 124 is shaped as a helix to allow recharge module freedom of movement some significant distance away from other modules 30 and 32 .
- Recharge module 34 can be moved to improve inductive coupling for energy transfer and/or the cosmetics of modular IMD 120 when implanted on cranium 12 .
- modular IMD 140 includes a single housing 142 to house both control module 30 and power source module 32 .
- Housing 142 may be hermetic and formed of titanium, stainless steel, or a ceramic.
- Recharge module 34 may, as shown in FIG. 11A, be tethered to housing 142 by flexible tether member 124 so that recharge module 34 can be moved freely relative to housing 142 .
- modular IMD 140 may, as shown in FIG. 11A, include a ceramic connector block 144 to receive leads 16 .
- FIG. 12 is a conceptual diagram illustrating a modular IMD 150 in which housing 36 of control module 30 and housing 38 of power source module 32 have substantially cylindrical shapes.
- the substantially cylindrical shapes of control module 30 and power source module 32 may enable IMD 150 to be implanted within the periphery, e.g., the limbs, of patient 14 .
- FIGS. 14A and 14B are top-view diagrams illustrating other example modular IMDs 170 and 180 .
- Modular IMDs 170 and 180 include at least one module in addition to control module 30 , power source module 32 , and recharge module 34 .
- modular IMDs 170 and 180 deliver one or more therapeutic agents to patient 14 .
- the housing of pump module 182 may be made from, for example, titanium, stainless steel, or a ceramic.
- a flexible interconnect member 184 carries one or more conductors used by processor 60 (FIG. 5) to control the delivery of the therapeutic agent to patient 14 by the pump within pump module 182 .
- the flexible interconnect member 184 may need to be hermetic, and may be made from, for example, titanium, stainless steel, or a ceramic.
- a flexible overmold 186 may at least partially encapsulate the housings of reservoir module 172 and pump module 182 , in addition to the housings of control module 30 , power source module 32 , and recharge module 34 .
Abstract
An implantable medical device includes a plurality of separately housed and flexibly interconnected modules. A first module includes a control electronics within a first housing, and may be coupled to a second module that includes a second housing by a flexible interconnect member. In some embodiments, an overmold, which may be flexible, at least partially encapsulates the first and second housings. The second module may be a power source module that includes a power source, such as a rechargeable battery, within the second housing. The implantable medical device may also include a third module, such as a recharge module that includes a coil within a third housing. The overmold may at least partially encapsulate the third housing, or the third module may be tethered to the overmold by a flexible tether member. A flexible interconnect member and/or flexible overmold may allow multiples degrees of freedom of movement between modules of an implantable medical device.
Description
- This application claims the benefit of:
- 1. U.S. Provisional Application entitled “CRANIAL NEUROSTIMULATOR AND METHOD,” Serial No. 60/431,854, (Attorney Docket No. P-10891.00), filed on Dec. 9, 2002;
- 2. U.S. Provisional Application entitled “IMPLANTABLE CRANIAL MEDICAL DEVICES AND METHODS,” Serial No. 60/471,262, (Attorney Docket No. P-11462.00), filed on May 16, 2003;
- 3. U.S. Provisional Application entitled “IMPLANTABLE CRANIAL MEDICAL DEVICES AND METHODS,” Serial No. 60/503,945, (Attorney Docket No. P-11696.00), filed on Sep. 20, 2003;
- 4. U.S. Provisional Application entitled “IMPLANTABLE CRANIAL MEDICAL DEVICES AND METHODS,” Serial No. 60/503,946, (Attorney Docket No. P-11697.0), filed on Sep. 20, 2003; and
- 5. U.S. Provisional Application entitled “Thin Neuro Stimulation System, Device and Method,” Serial No. 60/507,857, (Attorney Docket No. P-20211.00), filed on Oct. 1, 2003.
- The entire content of each of these U.S. Provisional Applications is incorporated herein by reference.
- The following co-pending and commonly-assigned U.S. patent applications, filed on even date herewith, are also incorporated herein by reference in their entirety:
- 1. U.S. patent application entitled “CONCAVITY OF AN IMPLANTABLE MEDICAL DEVICE,” to Carl D. Wahlstrand et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-336US01/P-11800.00;
- 2. U.S. patent application entitled “IMPLANTATION OF LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” to Ruchika Singhal et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-330US01/P-11795.00;
- 3. U.S. patent application entitled “COUPLING MODULE OF A MODULAR IMPLANTABLE MEDICAL DEVICE,” to Darren A. Janzig et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-331US01/P-11796.00;
- 4. U.S. patent application entitled “OVERMOLD FOR A MODULAR IMPLANTABLE MEDICAL DEVICE,” to Ruchika Singhal et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-332US01/P-11798.00;
- 5. U.S. patent application entitled “REDUCING RELATIVE INTERMODULE MOTION IN A MODULAR IMPLANTABLE MEDICAL DEVICE,” to Carl D. Wahlstrand et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-333US01/P-11797.00;
- 6. U.S. patent application entitled “LEAD CONNECTION MODULE OF A MODULAR IMPLANTABLE MEDICAL DEVICE,” to Ruchika Singhal et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-334US01/P-11799.00;
- 7. U.S. patent application entitled “LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” to Darren A. Janzig et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-335US01/P-11801.00; and
- 8. U.S. patent application entitled “MODULAR IMPLANTABLE MEDICAL DEVICE,” to Carl D. Wahlstrand et al., filed Dec. 9, 2003, assigned Attorney Docket No.: P-20542.00.
- The invention relates to medical devices, and more particularly, to implantable medical devices that deliver therapy to and/or monitor a patient.
- Depending on the application for which they are implanted in a patient, implantable medical devices (IMDs) may include a variety of electrical and/or mechanical components. Typically, an IMD includes a rigid housing that houses all of its components, which are generally fragile, to protect the components from forces to which they would otherwise be exposed when implanted within the human body. In order to avoid potentially harmful interactions between the components and bodily fluids, e.g., corrosion, IMD housings are typically hermetically sealed. Many IMD housings are fabricated from Titanium because of its desirable rigidity and biocompatibility.
- The size and shape of an IMD housing is dependant on the sizes and shapes of the components of the IMD. Large components common to most IMDs include a battery, a telemetry coil, and a circuit board that carries digital circuits, e.g., integrated circuit chips and/or a microprocessor, and analog circuit components. Attempts have been made to reduce the size of the IMD housing by reducing the size of these components, changing the shape of these components, and organizing these components within the IMD housing to avoid empty space within the housing. Despite these efforts to reduce the size of IMD housings, the size, shape and rigidity of IMD housings still greatly limits the locations within the human body where an IMD can be practically implanted.
- Due to these limitations, an IMD is typically implanted within the abdomen, upper pectoral region, or subclavicular region of a patient. Leads or catheters must be used in order to deliver therapy or monitor a physiological parameter at a location of the body other than where the IMD is implanted. Implantation and positioning of leads and catheters can be difficult and time-consuming from the perspective of a surgeon, particularly where the IMD is located a significant distance from the treatment or monitoring site. Moreover, the increased surgical time, increased surgical trauma, and increased amount of implanted material associated with the use of leads and catheters can increase the risk to the patient of complications associated with the implantation of an IMD.
- For example, IMDs that are used to treat or monitor the brain, e.g., to deliver deep brain stimulation (DBS) therapy, are implanted some distance away from the brain, e.g., within the subclavicular region of patients. The long leads that connect the implantable medical device to electrodes implanted within the brain require tunneling under the scalp and the skin of the neck, thereby requiring increased surgery and a prolonged amount of time under general anesthesia during the implant procedure, as well as increased recovery time. In some cases, tunneling the leads under the scalp and skin of the neck requires an additional surgical procedure under general anesthesia. The lengthy tract along the leads is more susceptible to infection, and the leads can erode the overlying scalp, forcing removal so that the scalp can heal. Further, the long leads running under the scalp and through the neck are more susceptible to fracture due to torsional and other forces caused by normal head and neck movements.
- In general, the invention is directed to an implantable medical device that includes a plurality of separately housed and flexibly interconnected modules. One of the modules is a control module that includes control electronics within a first housing. The control electronics control the functioning of the implantable medical device, and may include a processor.
- A second module may be a power source module that includes a power source within a second housing. The power source provides power to the first module, e.g., to the control electronics. The power source may be a rechargeable power source, such as a rechargeable battery or a capacitor.
- The first and second modules may be coupled by a flexible interconnect member, which may be hermetic. In various embodiments, the flexible interconnect member may include, for example, conductors to electrically couple the first and second modules. The flexible interconnect member may be flexible in more than one direction, providing the first and second modules with multiple degrees of freedom of motion with respect to each other including, in some embodiments, rotational motion. In exemplary embodiments, the flexible interconnect member provides at least three degrees of motion.
- In some embodiments, the implantable medical device includes an overmold that at least partially encapsulates the first and second housings. In embodiments in which the overmold does not completely encapsulate the first and second housings, the overmold may encapsulate an upper portion of the housings. Where such an implantable medical device is implanted on the cranium, lower portions of the housings may contact the cranium. In some embodiments, the overmold is flexible, may be comprised of silicone, and may include at least two materials. Together, a flexible overmold and flexible interconnect member may allow the modular implantable medical device to be manipulated during implantation to substantially conform to cranium.
- The implantable medical device may also include a third module, such as a recharge module that includes a coil within a third housing. In such embodiments, the coil inductively receives energy to recharge the power source within the second module. The overmold may at least partially encapsulate the third housing, or the third module may be tethered to the overmold by a tether member that allows the third module freedom of motion relative to the overmold such that the third module may be placed at a selected location some significant distance form the overmold and the other modules. The implantable medical device may include any number of modules in addition to the control module, and the additional modules are not limited to power source modules and/or recharge modules.
- In exemplary embodiments, the implantable medical device is configured for implantation on the cranium of a patient. Further, the implantable medical device may comprise a neurostimulator, and the control module may include therapy delivery circuitry for delivery of stimulation to the brain of a patient. The implantable medical device may include a lead connection module formed within the overmold to receive a lead or lead extension.
- In one embodiment, the invention is directed to an implantable medical device that includes a first module and a second module. The first module includes control electronics within a first housing. The second module includes a second housing. The implantable medical device further includes an overmold that at least partially encapsulates the first and second housings.
- In another embodiment, the invention is directed to an implantable medical device that includes a first module and a second module. The first module includes control electronics within a first housing. The second module includes a power source that provides power to the first module housed within a second housing. The implantable medical device further includes an interconnect member that flexibly couples the first and second modules.
- In another embodiment, the invention is directed to an implantable medical device that includes a first module and a second module. The first module includes control electronics housed within a first housing, and the second module that includes a power source that provides power to the first module housed within a second housing. The implantable medical device further includes a hermetic interconnect member that flexibly couples the first and second modules. The interconnect member is flexible in a plurality of directions and allows the first and second modules to have a plurality of degrees of freedom of movement relative to each other.
- In another embodiment, the invention is directed to an implantable neurostimulator for delivering stimulation to a brain of a patient that includes a first module and second module. The first module includes control electronics and a therapy delivery circuit housed within a first housing. The control electronics control delivery of stimulation by the therapy delivery circuit. The second module includes a power source within a second housing that provides power to the control electronics and the therapy delivery circuit. The implantable neurostimulator further includes an interconnect member that flexibly couples the first and second modules and includes a conductor for delivery power from the power source to the control electronics and the therapy delivery circuit, and a flexible overmold that at least partially encapsulates the first and second housings.
- In another embodiment, the invention is directed to an implantable medical device that includes control electronics and a rechargeable power source that provides power for the control electronics within a first housing. The implantable medical device further includes a recharge coil within a second housing that inductively receives energy to recharge the power source, and a flexible tether member that connects the first and second housings.
- The invention may be capable of providing one or more advantages. For example, by distributing components of an implantable medical device amongst modules rather than including them within a single, rigid housing, the implantable medical device may be shaped and configured for implantation at locations within the human body for which implantation of conventional implantable medical devices is deemed undesirable. A flexible interconnect member and/or flexible overmold may allow multiples degrees of freedom of movement between modules of an implantable medical device, allowing the implantable medical device to conform to such areas, and in particular embodiments, to conform to surfaces within the human body such as the surface of the cranium. The flexible interconnect member and/or flexible overmold may allow the implantable medical device to be manipulated during implantation to conform to craniums with various sizes and shapes.
- Because a modular implantable medical device according to the invention can be implanted on the cranium of a patient rather then more remotely from the brain, such as within a subclavicular region of the patient, the problems associated with the use of long leads needed to allow a remotely implanted medical device to access the brain may be diminished or avoided. Distribution of components of the implantable medical device within modules may reduce the effective thickness of the implantable medical device on the cranium making the implantable medical device less noticeable, e.g., more cosmetically appealing, when implanted on the cranium beneath the scalp of the patient. Further, in embodiments, that include an overmold, the overmold may be shaped to make the implantable medical device more cosmetically appealing and comfortable, and also more clinically acceptable, such as by including tapered edges that reduce the likelihood of skin erosion on the scalp over the device.
- The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other embodiments of the invention will be apparent from the description and drawings, and from the claims.
- FIG. 1 is a conceptual diagram illustrating an example modular implantable medical device implanted on the cranium of a patient.
- FIG. 2 is a top-view diagram further illustrating the modular implantable medical device of FIG. 1 implanted on the cranium of the patient.
- FIG. 3 is a top-view diagram further illustrating the modular implantable medical device of FIG. 1.
- FIG. 4 is top-view diagram illustrating a recharge module of the modular implantable medical device of FIG. 1.
- FIG. 5 is a block diagram illustrating a control module of the modular implantable medical device of FIG. 1.
- FIGS. 6A and 6B are top-view diagrams illustrating other example modular implantable medical devices.
- FIG. 7 is a block diagram illustrating a power source module of the modular implantable medical device of FIG. 6B.
- FIGS. 8A and 8B are cross-sectional diagrams illustrating two example configurations of the modular implantable medical device of FIG. 6B.
- FIGS. 9A and 9B are top-view diagrams illustrating another example modular implantable medical device that include a tethered recharge module.
- FIGS. 10, 11A,11B and 12 are conceptual diagrams illustrating other example modular implantable medical devices.
- FIG. 13 is a conceptual diagram illustrating a stacked circuit board.
- FIGS. 14A and 14B are top-view diagrams illustrating other modular implantable medical devices.
- FIG. 1 is a conceptual diagram illustrating an example modular implantable medical device (IMD)10 implanted on the
cranium 12 of apatient 14. As will be described in greater detail below,IMD 10 comprises a plurality of separately housed and flexibly interconnected modules. By distributing components ofIMD 10 amongst modules rather than including them within a single, rigid housing, the implantable medical device may be shaped and configured for implantation at locations withinpatient 14 for which implantation of conventional IMDs is deemed undesirable. Further, the flexibility of the interconnection between modules ofIMD 10 may allow multiples degrees of freedom of movement between the modules, which in turn may allow the implantable medical device to conform to such areas, and in particular embodiments, to conform to surfaces withinpatient 14 such as the surface ofcranium 12. - In the illustrated example,
modular IMD 10 is coupled to twoleads cranium 12, and into the brain ofpatient 14. In exemplary embodiments, each of leads 16 carries a plurality of electrodes, andIMD 10 delivers stimulation to the brain ofpatient 14 via the electrodes.Modular IMD 10 may be coupled to any number of leads 16, and in some embodiments is not coupled to any leads 16. - Because
modular IMD 10 can be implanted oncranium 12 ofpatient 14 rather then more remotely from the brain ofpatient 14, such as within an subclavicular region ofpatient 14, the problems associated with the use of long leads needed to allow a remotely implanted IMDs to access the brain may be diminished or avoided. These problems include the requirement of tunneling under the scalp and the skin of the neck, increased surgery and recovery time, an additional procedure under general anesthesia, risk of infection or skin erosion along the track through which the leads are tunneled, and risk of lead fracture due to torsional and other forces caused by normal head and neck movements. - FIG. 2 is a top-view diagram further illustrating
modular IMD 10 implanted oncranium 12 of thepatient 14. In order to implantmodular IMD 10 oncranium 12, anincision 20 is made through the scalp ofpatient 14, and a resulting flap of skin is pulled back to expose the desired area ofcranium 12. The incision may, as shown in FIG. 2, be generally shaped like a “C.” Such an incision is commonly referred to as a “C-flap” incision. -
Holes cranium 12, and leads 16 are inserted through holes 22 and into the brain ofpatient 14. Caps may be placed over holes 22 as is known in the art. Leads 16 are connected tomodular IMD 10, either directly or via a lead extension, andmodular IMD 10 is placed at least partially within a pocket formed using a hand or a tool beneath the scalp behind holes 22. - Once positioned as desired on
cranium 12 within the pocket,modular IMD 10 may then be fixed tocranium 12 using an attachment mechanism such as bone screws. The skin flap may be closed overmodular IMD 10, and the incision may be stapled or sutured. The location oncranium 12 at whichIMD 10 is illustrated as implanted in FIG. 2 is merely exemplary, andIMD 10 can be implanted anywhere on the surface ofcranium 12. Further details regarding exemplary techniques for implantingIMD 10 on the cranium may be found in a commonly-assigned U.S. patent application entitled “IMPLANTATION OF LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-330US01/P-11795.00. - Because of the flexibility provided by interconnect members and/or an overmold of
modular IMD 10, the IMD may be manipulated during implantation such that it conforms to cranium 12. For example, in some embodiments a clinician can manipulatemodular IMD 10 into conformance withcranium 12 whileIMD 10 is oncranium 12 and fixmodular IMD 10 into place using bone screws or the like. In other embodiments, the clinician may manipulatemodular IMD 10 into conformance withcranium 12 withIMD 10 on and/or off ofcranium 12, andIMD 10 may substantially retain the form into which it is manipulated. - As mentioned above,
modular IMD 10 may deliver stimulation to the brain ofpatient 14 to, for example, provide deep brain stimulation (DBS) therapy, or to stimulate the cortex of the brain. Cortical stimulation may involve stimulation of the motor cortex.Modular IMD 10 may be used to treat any nervous system disorder including, but not limited to, epilepsy, pain, psychological disorders including mood and anxiety disorders, movement disorders (MVD), such as, but not limited to, essential tremor, Parkinson's disease, and neurodegenerative disorders. - However,
modular IMD 10 is not limited to delivery of stimulation to the brain of patient, and may be employed with leads 16 deployed anywhere in the head or neck including, for example, leads deployed on or near the surface of the skull, leads deployed beneath the skull such as near or on the dura mater, leads placed adjacent cranial or other nerves in the neck or head, or leads placed directly on the surface of the brain. Moreover,modular IMD 10 is not limited to implantation oncranium 12. Indeed,modular IMD 10 may be implanted anywhere withinpatient 14. For example,modular IMD 10 can be implanted within the neck ofpatient 14, and deliver stimulation to the vagus nerve or the cervical region of the spinal cord. -
Modular IMD 10 may alternatively be implanted within a pectoral region or the abdomen ofpatient 14 to act as a diaphragmatic pacer, or to provide any of the monitoring and therapy delivery functions known in the art to be associated with cardiac pacemakers. Further,modular IMD 10 may be implanted in the upper buttock region and deliver spinal cord, urological or gastrological stimulation therapy, or may be configured to be implanted within the periphery, e.g., limbs, ofpatient 14 for delivery of stimulation to the muscles and/or peripheral nervous system ofpatient 14. As is the case withcranium 12, the modularity ofIMD 10 may enable implantation at some of these example locations for which implantation of conventional IMDs is generally deemed undesirable. -
Modular IMD 10 is not limited to embodiments that deliver stimulation. For example, in some embodimentsmodular IMD 10 may additionally or alternatively monitor one or more physiological parameters and/or the activity ofpatient 14, and may include sensors for these purposes. Where a therapy is delivered,modular IMD 10 may operate in an open loop mode (also referred to as non-responsive operation), or in a closed loop mode (also referred to as responsive).Modular IMD 10 may also provide warnings based on the monitoring. - As discussed above, the ability of a
modular IMD 10 according to the invention to be implanted close to a region withinpatient 14 to be monitored enables the use of shorter leads 16. Shorter leads 16 may advantageously improve the accuracy of such sensors by reducing noise attributable to leads 16. Shorter leads 16 may also advantageously reduce the negative affects of imaging techniques such as magnetic resonance imaging “MRI” on a person implanted withIMD 10. - Further, in some embodiments
modular IMD 10 can additionally or alternatively deliver a therapeutic agent topatient 14, such as a pharmaceutical, biological, or genetic agent.Modular IMD 10 may be coupled to a catheter, and may include a pump to deliver the therapeutic agent via the catheter. - FIG. 3 is a top-view diagram further illustrating
modular IMD 10. In the illustrated embodiment,modular IMD 10 includes three modules: acontrol module 30, apower source module 32, and arecharge module 34. As shown in FIG. 3,modules separate housings -
Control module 30 includes control electronics within the housing, e.g., electronics that control the monitoring and/or therapy delivery functions ofmodular IMD 10, such as a microprocessor.Control module 30 may also include circuits for telemetry communication with external programmers or other devices within the housing.Housing 36 ofcontrol module 30 may be hermetic in order to protect the control electronics therein, and in exemplary embodiments is formed of a rigid material, such as titanium, stainless steel, or a ceramic. In exemplary embodiments,housing 36 is a low-profile, concave housing, and techniques for arranging components ofcontrol module 30 to enable such a low-profile, concave housing are described in greater detail in a commonly-assigned U.S. patent application entitled “LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-335US01/P-11801.00. -
Power source module 32 includes a power source withinhousing 38. The power source provides power for components of other modules, such as the control electronics withincontrol module 30. The power source may be any power source suitable for use within an IMD, such as one or more batteries, capacitors, solar cells, fuel cells, nuclear cells, or any combination thereof. In an exemplary embodiment, the power source comprises a rechargeable Lithium Ion battery, which may have a thin wound coil construction, or a foil pack or other non-coiled construction to more easily fit withinhousing 38 which may be less than 5 millimeters thick with an approximately one square inch surface area.Housing 38 may be hermetic, and may be formed of titanium, stainless steel, or a ceramic.Power source module 32 may include an insulator withinhousing 38 to isolatehousing 38 from the power source. - Where the power source includes a rechargeable power, such as a rechargeable battery and/or a capacitor,
modular IMD 10 may includerecharge module 34. As shown in FIG. 4,recharge module 34 includes arecharge coil 42 withinhousing 40.Recharge coil 42 inductively receives energy from an external recharging unit (not illustrated) through the skin ofpatient 14 to recharge the power source.Recharge coil 42 may be formed of windings of copper or another highly conductive material.Housing 40 need not be hermetic, and may be formed of materials such as silicone, polymers and ceramics. -
Housings housings housings -
Modules modular IMD 10 can include any number of modules, and may include other types of modules instead of or in addition to apower source module 32 and arecharge module 34. For example,modular IMD 10 can include additional power source modules, modules that include additional memory that is accessible by the control electronics withincontrol module 30, modules that include reservoirs for storing therapeutic agents and pumps for delivering therapeutic agents topatient 14, and modules that include sensors sensing physiological parameters, such as pressures or blood flows, or the activity level ofpatient 12. -
Power source module 32 is coupled to controlmodule 30 by aflexible interconnect member 44, which encloses a conductor that allows transmission of energy from the power source ofpower source module 32 to components such as the control electronics withincontrol module 30. In embodiments where energy is transferred via a DC voltage on the conductor, it may be necessary to makeflexible interconnect member 44 hermetic. In embodiments in whichflexible interconnect member 44 is hermetic,flexible interconnect member 44 may be made of titanium or stainless steel. In embodiments where energy is transferred via a charge-balance voltage on the conductor, such as an AC voltage,flexible interconnect member 44 need not be hermetic, and may be made of any material including silicone or various polymers. - In the illustrated embodiment, the control electronics of
control module 30 regulates the recharging and discharging of the power source withinpower source module 32. Consequently, as shown in FIG. 3,recharge module 34 is coupled to controlmodule 30 by aflexible interconnect member 46 that encloses a conductor that allows transmission of energy inductively received bycoil 42 to controlmodule 30. Because the energy is transferred on the conductor via a charge-balanced voltage,flexible interconnect member 46 need not be hermetic, and may be made of any material including titanium, stainless steel, ceramics, silicone or various polymers. -
Interconnect members interconnect members flexible member 44 is hermetic and made of substantially less flexible material, such as titanium or stainless steel, the flexibility ofinterconnect member 44 is provided by the configuration and/or construction offlexible interconnect member 44. -
Interconnect member 44 is flexible in a plurality of directions to providemodules interconnect member 44 provides at least three degrees of motion, and the degrees of motion provided include rotational motion. Further details regarding the configuration and/or construction ofinterconnect member 44 to provide such flexibility may be found in a commonly-assigned U.S. patent application entitled “COUPLING MODULE OF MODULAR IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-331US01/P-11796.00. - As shown in FIG. 3,
modular IMD 10 includes anovermold 48, which may be flexible. In the illustrated embodiment, overmold 48 at least partially encapsulates each ofhousings Overmold 48 integratesmodules overmold 48 incorporates mechanical features to restrict intermodule motion to certain directions or within certain ranges.Overmold 48 may be made from silicone, and is some embodiments may be made from two or more materials of differing flexibility, such as silicone and a polyurethane. An exemplary polyurethane for this purpose is Tecothane®, which is commercially available from Hermedics Polymer Products, Wilmington, Mass. Use of the term “overmold” herein is not intend to limit the invention to embodiments in which overmold 48 is a molded structure.Overmold 48 may be a molded structure, or may be a structure formed by any process. - Overmold48 can be shaped to contour to
cranium 12, e.g., may be concave along at least one axis, and may be contoured at its edges to prevent skin erosion on the scalp ofpatient 14. The flexibility and shape ofovermold 48 may improve the comfort and cosmetic appearance ofmodular IMD 10 under the scalp. Further details regarding the overmold, the concavity of the flexible overmold, and techniques for restricting intermodular motion in amodular IMD 10 may be found in a commonly-assigned U.S. patent application entitled “OVERMOLD FOR A MODULAR IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-332US01/P-11798.00, and a commonly-assigned U.S. patent application entitled “REDUCING RELATIVE INTERMODULE MOTION IN A MODULAR IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-333US01/P-11797.00. - In the illustrated embodiment,
modular IMD 10 also includeslead connector modules overmold 48 to receive leads 16 or lead extensions coupled to leads 16.Conductors 52 extend from lead connector modules 50 to hermetic feedthroughs (not illustrated) withinhousing 36 ofcontrol module 30. Lead connector modules 50 may be formed anywhere withinovermold 48. In embodiments whereovermold 48 includes a rigid material in addition to a flexible material, the rigid material may form at least part of lead connector modules 50 to secure leads 16 or lead extensions, and to protectconductors 52 from damage that may result from flexing withinovermold 48. - FIG. 5 is a block diagram illustrating
control module 30 ofmodular IMD 10. As described above,control module 30 includes control electronics that control the functioning ofmodular IMD 10 withinhousing 36. The control electronics include aprocessor 60, which may take the form of a microprocessor, digital signal processor (DSP), application specific integrated circuit (ASIC), field-programmable gate array (FPGA), or other logic circuitry. -
Control module 30 also includes amemory 62, such as a read-only memory (ROM), random access memory (RAM), electronically-erasable programmable ROM (EEPROM), flash memory, or the like.Memory 62 may store program instructions that may be executed byprocessor 60 and thereby control the functioning ofmodular IMD 10.Processor 60 may also store data colleted during treatment and/or monitoring ofpatient 14 withinmemory 62. - In some embodiments,
control module 30 includestelemetry circuitry 64, which enablesprocessor 60 to communicate with other devices such as an external programming device via radio-frequency communication.Telemetry circuitry 64 may include a telemetry coil (not illustrated), which may be fabricated of windings of copper or another highly conductive material. The configuration and location of telemetry coil withinhousing 36 may be dictated by the available space withinhousing 36 and the communication requirements oftelemetry circuitry 64. Further detail regarding the configuration and location of the telemetry coil may be found in a commonly-assigned U.S. patent application entitled “LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No: 1023-335US01/P-11801.00. - In some embodiments
modular IMD 10 delivers electrical stimulation, and more particularly,control module 30 includestherapy delivery circuitry 66 withinhousing 36 that generates electrical stimulation. In exemplary embodiments,therapy delivery circuitry 66 comprises circuits for the generation of electrical stimulation in the form of pulses, such as capacitors and switches. In embodiments in whichmodular IMD 10 is a neurostimulator coupled to leads 16 that include a plurality of electrodes,therapy delivery circuitry 66 may deliver the pulses to aswitch matrix 68, which comprises an array of switches. In such embodiments,processor 60 interacts withswitch matrix 68 to select electrodes for delivery of generated stimulation pulses. Based on the selections made byprocessor 60,switch matrix 68 delivers the pulses to conductors that pass through feedthroughs inhousing 36 and to electrical contacts on leads 16 that are electrically coupled to the desired electrodes carried by leads 16. - The illustrated components of
control module 30 receive energy from the power source withinpower source module 32 via interconnect member 44 (FIG. 3). In some embodiments in which the power source is rechargeable,control module 30 receives energy inductively captured byrecharge module 34 viainterconnect member 46, and includespower management circuitry 70 that controls the recharging and discharging of the power source.Power management circuitry 70 may ensure that the power source is not overcharged, over-discharged, or harmed. In some embodiments,power management circuitry 70 includes circuits to measure voltages, currents or temperatures associated with the power source, or rates of change of these parameters, and controls recharging and discharging according to the measured values.Power management circuitry 70 may also include circuits, such as rectifier circuits, for converting charge-balanced voltages, e.g., AC voltages, provided by recharge coil 42 (FIG. 4) into DC voltages for recharging the power source. - FIGS. 6A and 6B are top-view diagrams illustrating other example
modular IMDs modular IMDs modules flexible interconnect members modules IMDs - FIGS. 3 and 6A illustrate substantially triangular configurations of
modules modular IMDs IMDs modules overmolds patient 14. Reduced pocket depth may allow for easier explant ofmodular IMDs modules modular IMD 90 illustrated FIG. 6B. - Although illustrated in FIGS. 3, 6A and6B as connecting
recharge module 34 to controlmodule 30, in some embodimentsflexible interconnect member 44 directly connectsrecharge module 34 topower source module 32. Consequently, in such embodimentspower source module 32 includes circuitry to control the recharging and discharging of the power source instead of, or in addition topower management circuit 70 withincontrol module 30. - FIG. 7 is a block diagram illustrating
power source module 32 ofmodular IMD 90.Power source module 32 includes arechargeable power source 100 withinhousing 38, which may include a battery and/or a capacitor. In the illustrated embodiment in whichpower source module 32 directly receives energy inductively captured byrecharge module 34 viaflexible interconnect member 44,power source module 32 also includepower management circuit 102 that controls the recharging and discharging ofpower source 100. As described above with reference topower management circuitry 70 illustrated in FIG. 5,power management circuitry 102 may ensure thatpower source 100 is not overcharged, over-discharged, or harmed. In some embodiments,power management circuitry 102 includes circuits to measure voltages, currents or temperatures associated withpower source 100, or rates of change of these parameters, and controls recharging and discharging ofpower source 100 according to the measured values. -
Power management circuitry 102 may also include circuits, such as rectifier circuits, for converting charge-balanced voltages, e.g., AC voltages, provided by recharge coil 42 (FIG. 4) into DC voltages for rechargingpower source 100. In some embodiments in whichinterconnect member 44 is non-hermetic,power management circuit 102 includes modulating circuits, i.e., circuits that enablepower management circuit 102 to deliver energy to controlmodule 30 in the form of charge-balanced voltages on a conductor. In such embodiments,control module 30 includes circuits, such as rectifier circuits, to convert the charge-balanced voltages to DC voltages for use by components ofcontrol module 30. - FIGS. 8A and 8B are cross-sectional diagrams illustrating two example configurations of
overmold 92 ofmodular IMD 90, the cross-section taken along axis 94 (FIG. 6B). FIG. 8A illustrates an embodiment ofIMD 90 in which overmold 92 fully encapsulatesmodules IMD 90 in which overmold 92 partially encapsulatesmodules overmold 92 partially encapsulatesmodules overmold 92leaves portions modules Portions modules cranium 12 whenmodular IMD 90 is implanted thereon. - Embodiments in which overmold92 fully encapsulates
modules portions cranium 12 that are sized to receive the portions. By recessingportions modular IMD 90 abovecranium 12 may be reduced. - FIGS. 9A and 9B are top-view diagrams illustrating another example
modular IMD 120. In the illustrated embodiment,recharge module 34 is not encapsulated byovermold 122, but is instead tethered to overmold 122 by aflexible tether member 124.Flexible tether member 124 is made of a flexible material, such as silicone, to allow substantial movement ofrecharge module 34 relative toother modules flexible tether member 124 is shaped as a helix to allow recharge module freedom of movement some significant distance away fromother modules Recharge module 34 can be moved to improve inductive coupling for energy transfer and/or the cosmetics ofmodular IMD 120 when implanted oncranium 12. - FIGS. 10, 11A,11B and 12 are conceptual diagrams illustrating other example
modular IMDs Modular IMD 130 of FIG. 10 does not includerecharge module 34. Rather, rechargecoil 42 is embedded withinovermold 132, and surroundscontrol module 30 andpower source module 32. - In some embodiments, such as
modular IMD 140 illustrated in FIGS. 11A and 11B,control module 30 andpower source module 32 are not separately housed. Rather, as illustrated in FIG. 11A,modular IMD 140 includes asingle housing 142 to house bothcontrol module 30 andpower source module 32.Housing 142 may be hermetic and formed of titanium, stainless steel, or a ceramic.Recharge module 34 may, as shown in FIG. 11A, be tethered tohousing 142 byflexible tether member 124 so thatrecharge module 34 can be moved freely relative tohousing 142. Further,modular IMD 140 may, as shown in FIG. 11A, include aceramic connector block 144 to receive leads 16. - FIG. 11B illustrates a side-profile of
modular IMD 140.Housing 142 may be a low-profile housing with athickness 146 that is approximately less than or equal to 6 millimeters. Techniques for arranging components of an IMD to enable a low-profile housing may be found in the commonly-assigned U.S. patent application entitled “LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No: 1023-335US01/P-11801.00. A low-profile housing 142 may allowmodular IMD 140 to be implanted, for example, within an upper buttocks region ofpatient 14. - FIG. 12 is a conceptual diagram illustrating a
modular IMD 150 in whichhousing 36 ofcontrol module 30 andhousing 38 ofpower source module 32 have substantially cylindrical shapes. The substantially cylindrical shapes ofcontrol module 30 andpower source module 32 may enableIMD 150 to be implanted within the periphery, e.g., the limbs, ofpatient 14. - As illustrated in FIG. 13, a
circuit board 160 withincontrol module 30 may includeflex tape regions 162 that enable thecircuit board 160 to have a “stacked” configuration. The stacked configuration ofcircuit board 160 can enablecircuit board 160 to fit withincylindrical housing 36 illustrated in FIG. 12. In some embodiments,circuit board 160 may be constructed entirely of flex tape, and may be have a “rolled” configuration that can enablecircuit board 160 to fit withincylindrical housing 36 illustrated in FIG. 12. A variety of primary and rechargeable batteries that have substantially cylindrical shapes are commercially available, and can be used as a cylindrically-shapedpower source module 32. - FIGS. 14A and 14B are top-view diagrams illustrating other example
modular IMDs Modular IMDs control module 30,power source module 32, andrecharge module 34. In particular, instead of or in addition to delivering electrical stimulation,modular IMDs patient 14. -
Modular IMDs patient 14.Modular IMD 170 includes areservoir module 172 that contains the therapeutic agent within a housing. The housing may contain a bladder that holds the therapeutic agent, and may provide access to the bladder for refilling. The housing may be formed of, for example, titanium, stainless steel, a ceramic, a polymer, or silicone. - In such embodiments,
control module 30 includes a pump (not shown), and processor 60 (FIG. 5) controls delivery of the therapeutic agent by the pump. The pump withincontrol module 30 receives the therapeutic agent fromreservoir module 172 via aflexible interconnect member 174 that includes to enable transfer of the therapeutic agent.Flexible interconnect member 174 need not be hermetic, and may be made from, for example, titanium, stainless steel, a ceramic, a polymer, or silicone. Anovermold 176 may at least partially encapsulate the housing ofreservoir module 172 in addition to the housings ofcontrol module 30,power source module 32, andrecharge module 34. -
Modular IMD 180 illustrated in FIG. 14B includes a separately housedpump module 182 that includes a pump. The pump withinpump module 182 may be used to deliver the therapeutic agent withinreservoir module 172 instead of or in addition to a pump withincontrol module 30. In the illustrated embodiment,pump module 182 rather than controlmodule 30 is coupled toreservoir module 172 byflexible interconnect member 174, and the pump withinpump module 182 receives the therapeutic agent withinreservoir module 172 via a lumen withinflexible interconnect member 174. - The housing of
pump module 182 may be made from, for example, titanium, stainless steel, or a ceramic. Aflexible interconnect member 184 carries one or more conductors used by processor 60 (FIG. 5) to control the delivery of the therapeutic agent to patient 14 by the pump withinpump module 182. Theflexible interconnect member 184 may need to be hermetic, and may be made from, for example, titanium, stainless steel, or a ceramic. Aflexible overmold 186 may at least partially encapsulate the housings ofreservoir module 172 andpump module 182, in addition to the housings ofcontrol module 30,power source module 32, andrecharge module 34. - Various embodiments of the invention have been described. These and other embodiments are within the scope of the following claims.
Claims (57)
1. An implantable medical device comprising:
a first module that includes control electronics within a first housing;
a second module that includes a second housing; and
an overmold that at least partially encapsulates the first and second housings.
2. The implantable medical device of claim 1 , wherein the second module includes a power source within the second housing that provides power to the first module.
3. The implantable medical device of claim 2 , wherein the power source is rechargeable.
4. The implantable medical device of claim 3 , further comprising a recharge coil that inductively receives energy to recharge the power source.
5. The implantable medical device of claim 4 , wherein the recharge coil is located within the overmold and substantially encircles the first and second modules.
6. The implantable medical device of claim 4 , further comprising a third module that includes a third housing that houses the recharge coil.
7. The implantable medical device of claim 6 , wherein the overmold at least partially encapsulates the third module.
8. The implantable medical device of claim 7 , wherein the first, second and third modules are positioned within the overmold in one of a triangular configuration and a linear configuration.
9. The implantable medical device of claim 6 , wherein the third module is located outside of the overmold, the implantable medical device further comprising a flexible tether member that connects the third module to the overmold.
10. The implantable medical device of claim 9 , wherein the flexible tether member comprises a helix.
11. The implantable medical device of claim 1 , wherein the overmold completely encapsulates the first and second modules.
12. The implantable medical device of claim 1 , wherein the overmold does not encapsulate a portion of each of the first and second modules, and each of the portions is proximate to a cranium of a patient when the implantable medical device is implanted on the cranium.
13. The implantable medical device of claim 1 , wherein the overmold is flexible.
14. The implantable medical device of claim 1 , wherein the overmold comprises silicone.
15. The implantable medical device of claim 1 , wherein the overmold comprises at least two materials.
16. The implantable medical device of claim 1 , further comprising a flexible interconnect member to couple the first and second modules.
17. The implantable medical device of claim 16 , wherein the interconnect member is flexible in a plurality of directions and allows the first and second modules to have a plurality of degrees of freedom of movement relative to each other.
18. The implantable medical device of claim 1 , wherein each of the first and second housings are substantially cylindrical.
19. The implantable medical device of claim 1 , further comprising:
a lead connection module formed within the overmold to receive one of a lead that includes an electrode and a lead extension that is coupled to the lead; and
a conductor that extends from the lead connection module to the first module, wherein the first housing comprises a hermetic feedthrough to receive the conductor and the conductor electrically couples the electrode to the first module.
20. The implantable medical device of claim 1 , wherein the first module comprises a therapy delivery circuit to deliver electrical stimulation to a patient, and the control electronics control the delivery of electrical stimulation by the therapy delivery circuit.
21. The implantable medical device of claim 1 , wherein the overmold is shaped for implantation on a cranium of a patient.
22. The implantable medical device of claim 1 , wherein the implantable medical device is flexible such that a shape of the implantable medical device is capable of being manipulated.
23. An implantable medical device comprising:
a first module that includes control electronics housed within a first housing;
a second module that includes a power source that provides power to the first module housed within a second housing; and
an interconnect member that flexibly couples the first and second modules.
24. The implantable medical device of claim 23 , wherein the power source is rechargeable.
25. The implantable medical device of claim 24 , further comprising a recharge coil that inductively receives energy to recharge the power source.
26. The implantable medical device of claim 25 , wherein the recharge coil is located within an overmold and substantially encircles the first and second modules.
27. The implantable medical device of claim 25 , further comprising a third module that includes a third housing that houses the recharge coil.
28. The implantable medical device of claim 27 , wherein an overmold at least partially encapsulates the third module.
29. The implantable medical device of claim 28 , wherein the first, second and third modules are positioned within the overmold in one of a triangular configuration and a linear configuration in which the modules are positioned substantially along a common axis.
30. The implantable medical device of claim 27 , wherein the third module is located outside of the overmold, the implantable medical device further comprising a flexible tether member that connects the third module to the overmold.
31. The implantable medical device of claim 30 , wherein the flexible tether member comprises a helix.
32. The implantable medical device of claim 23 , wherein the interconnect member is flexible in a plurality of directions and allows the first and second modules to have a plurality of degrees of freedom of movement relative to each other.
33. The implantable medical device of claim 32 , wherein the interconnect member allows the first and second modules to have at least three degrees of freedom of movement relative to each other.
34. The implantable medical device of claim 33 , wherein the interconnect member is hermetic.
35. The implantable medical device of claim 23 , wherein each of the first and second housings are substantially cylindrical.
36. The implantable medical device of claim 23 , further comprising:
a lead connection module formed within an overmold to receive one of a lead that includes an electrode and a lead extension that is coupled to the lead; and
a conductor that extends from the lead connection module to the first module, wherein the first housing comprises a hermetic feedthrough to receive the conductor and the conductor electrically couples the electrode to the first module.
37. The implantable medical device of claim 23 , wherein the first module comprises a therapy delivery circuit to deliver electrical stimulation to a patient, and the control electronics control the delivery of electrical stimulation by the therapy delivery circuit.
38. The implantable medical device of claim 23 , wherein the implantable medical device is flexible such that a shape of the implantable medical device is capable of being manipulated.
39. An implantable medical device comprising:
a first module that includes control electronics housed within a first housing;
a second module that includes a power source that provides power to the first module housed within a second housing; and
a hermetic interconnect member that flexibly couples the first and second modules, wherein the interconnect member is flexible in a plurality of directions and allows the first and second modules to have a plurality of degrees of freedom of movement relative to each other.
40. The implantable medical device of claim 39 , wherein the interconnect member allows the first and second modules to have at least three degrees of freedom of movement relative to each other.
41. The implantable medical device of claim 39 , wherein the implantable medical device is flexible such that a shape of the implantable medical device is capable of being manipulated.
42. An implantable medical device comprising:
a first module comprising control electronics and a therapy delivery circuit housed within a first housing, wherein the control electronics control delivery of stimulation by the therapy delivery circuit;
a second module comprising a power source within a second housing that provides power to the control electronics and the therapy delivery circuit;
an interconnect member that flexibly couples the first and second modules and includes a conductor for delivery power from the power source to the control electronics and the therapy delivery circuit; and
a flexible overmold that at least partially encapsulates the first and second housings.
43. The implantable medical device of claim 42 , wherein the power source is rechargeable.
44. The implantable medical device of claim 43 , further comprising a recharge coil that inductively receives energy to recharge the power source.
45. The implantable medical device of claim 44 , wherein the recharge coil is located within the flexible overmold and substantially encircles the first and second modules.
46. The implantable medical device of claim 44 , further comprising a third module that includes a third housing that houses the recharge coil.
47. The implantable medical device of claim 46 , wherein the flexible overmold at least partially encapsulates the third module.
48. The implantable medical device of claim 47 , wherein the first, second and third modules are positioned within the overmold in one of a triangular configuration and a linear configuration in which the modules are positioned substantially along a common axis.
49. The implantable medical device of claim 46 , wherein the third module is located outside of the overmold, the implantable medical device further comprising a flexible tether member that connects the third module to the overmold.
50. The implantable medical device of claim 49 , wherein the flexible tether member comprises a helix.
51. The implantable medical device of claim 42 , wherein the interconnect member is flexible in a plurality of directions and allows the first and second modules to have a plurality of degrees of freedom of movement relative to each other.
52. The implantable medical device of claim 42 , further comprising:
a lead connection module formed within the overmold to receive one of a lead that includes an electrode and a lead extension that is coupled to the lead; and
a conductor that extends from the lead connection module to the first module, wherein the first housing comprises a hermetic feedthrough to receive the conductor and the conductor electrically couples the electrode to the first module.
53. The implantable medical device of claim 42 , wherein the overmold is shaped for implantation on a cranium of a patient.
54. The implantable medical device of claim 42 , wherein the implantable medical device is flexible such that a shape of the implantable medical device is capable of being manipulated.
55. The implantable medical device of claim 42 , wherein the therapy delivery circuit comprises a pulse generator.
56. An implantable medical device comprising:
control electronics and a rechargeable power source that provides power for the control electronics within a first housing;
a recharge coil within a second housing that inductively receives energy to recharge the power source; and
a flexible tether member that connects the first and second housings.
57. The implantable medical device of claim 56 , wherein the flexible tether member comprises a helix.
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US10/731,699 Active 2028-03-08 US7848817B2 (en) | 2002-12-09 | 2003-12-09 | Coupling module of a modular implantable medical device |
US10/731,868 Active 2026-02-11 US8397732B2 (en) | 2002-12-09 | 2003-12-09 | Implantation of low-profile implantable medical device |
US10/731,881 Expired - Fee Related US7392089B2 (en) | 2002-12-09 | 2003-12-09 | Reducing relative intermodule motion in a modular implantable medical device |
US10/731,869 Abandoned US20040176818A1 (en) | 2002-12-09 | 2003-12-09 | Modular implantable medical device |
US10/730,877 Active 2027-06-08 US8457744B2 (en) | 2002-12-09 | 2003-12-09 | Low-profile implantable medical device |
US10/730,873 Expired - Lifetime US7242982B2 (en) | 2002-12-09 | 2003-12-09 | Overmold for a modular implantable medical device |
US10/731,638 Expired - Lifetime US7212864B2 (en) | 2002-12-09 | 2003-12-09 | Modular implantable medical device |
US11/735,826 Abandoned US20070185539A1 (en) | 2002-12-09 | 2007-04-16 | Overmold for a modular implantable medical device |
US12/942,806 Active 2025-07-11 US8666497B2 (en) | 2002-12-09 | 2010-11-09 | Coupling module of a modular implantable medical device |
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