US20060241519A1 - Guidewire with deflectable tip - Google Patents

Guidewire with deflectable tip Download PDF

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Publication number
US20060241519A1
US20060241519A1 US11/473,764 US47376406A US2006241519A1 US 20060241519 A1 US20060241519 A1 US 20060241519A1 US 47376406 A US47376406 A US 47376406A US 2006241519 A1 US2006241519 A1 US 2006241519A1
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United States
Prior art keywords
distal
proximal
deflection
ribbon
helical coil
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US11/473,764
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Hikmat Hojeibane
David Grewe
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Individual
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Individual
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Priority to US11/473,764 priority Critical patent/US20060241519A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0133Tip steering devices
    • A61M25/0147Tip steering devices with movable mechanical means, e.g. pull wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0133Tip steering devices
    • A61M25/0152Tip steering devices with pre-shaped mechanisms, e.g. pre-shaped stylets or pre-shaped outer tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M2025/0042Microcatheters, cannula or the like having outside diameters around 1 mm or less
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09058Basic structures of guide wires
    • A61M2025/09083Basic structures of guide wires having a coil around a core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09133Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0133Tip steering devices
    • A61M25/0138Tip steering devices having flexible regions as a result of weakened outer material, e.g. slots, slits, cuts, joints or coils
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M25/09016Guide wires with mandrils
    • A61M25/09033Guide wires with mandrils with fixed mandrils, e.g. mandrils fixed to tip; Tensionable wires

Definitions

  • the present invention relates to a steerable guidewire, and more particularly to a bi-directional steerable guidewire having a tip which may be very precisely “steered,” or deflected.
  • the guidewire is particularly suitable for use in conjunction with the insertion of a catheter into a vessel of the body, or alternatively, the guidewire may be used by itself to open obstructions within a vessel or to carry a therapeutic device for removing obstructions within a vessel.
  • guidewires have included a core wire with the distal end being tapered and with a coil spring mounted on the tapered distal end. These guidewires have been used to facilitate the insertion of a catheter into a vessel of the body. Generally, the guidewire is inserted into a vessel, a catheter is inserted over the guidewire and the catheter is then moved through the vessel until the distal end of the catheter is positioned at a desired location. The guidewire is then retracted from the catheter and the catheter is left in the vessel. Alternatively, the guidewire may be first inserted into the catheter with the distal portion of the guidewire extending beyond the distal end of the catheter.
  • This assembly is then inserted into a vessel with the distal tip of the guidewire being used to facilitate movement of the guidewire and catheter through the vessel. Again, when the distal tip of the catheter has been placed in a desired location, the guidewire may be retracted thereby leaving the catheter in place within the vessel.
  • Another common application for guidewires is that of using the distal tip of the guidewire for removing an obstruction within a vessel. Often times this procedure is accomplished by inserting the guidewire within a vessel, moving the distal tip of the guidewire into contact with the obstruction and then very gently tapping the distal tip of the guidewire against the obstruction until the guidewire passes through the obstruction.
  • various types of devices may be placed on the distal end of a guidewire for actively opening an obstruction within the vessel. Examples of such devices which may be placed on the end of the guidewires are disclosed in the following United States patents to Robert C. Stevens: U.S. Pat. Nos. 5,116,350; 5,078,722; 4 , 936 , 845 ; 4 , 923 , 462 ; and, 4 , 854 , 325 .
  • a very small diameter steerable guidewire having a deflectable tip which includes an elongated flexible tubing, a flexible helical coil attached to the distal portion of the flexible tubing, an elongated deflection member which is slidably disposed within the tubing and within the helical coil.
  • the proximal portion of the deflection member is of a cylindrical configuration and the distal portion is tapered to form a deflection ribbon.
  • the deflection member may take the form of a proximal cylindrical wire which is attached at its distal end to a deflection ribbon.
  • a retaining ribbon is attached to the distal end of the flexible tubing and is oriented to extend in a plane which is generally parallel to the plane of the ribbon portion of the deflection member.
  • An attachment member which may take the form of a rounded bead, preferably formed from epoxy, is bonded to the distal end of the helical coil, the distal end of the deflection ribbon and the distal end of the retaining ribbon so that longitudinal movement of the deflection member causes the distal end of the helical coil to be deflected.
  • the retaining ribbon and the deflection ribbon are preferably pre-shaped into a curved configuration to thereby cause the flexible helical coil to be biased into a normally curved shape.
  • the distal portion of the deflection ribbon engages the attachment member, or rounded bead, at a location offset from the center of the attachment member, and the distal portion of the retaining ribbon engages the attachment member at a location offset from the center of the attachment member.
  • the retaining ribbon engages the attachment member at a location offset from the center portion of the attachment member in the opposite direction from the offset location of the deflection ribbon.
  • the deflection ribbon and the retaining ribbon are connected to each other within the attachment member.
  • these two elements are formed as a single unitary element.
  • the cylindrical deflection member is flattened to form the deflection ribbon and is further flattened at its distal end to form the retaining ribbon.
  • the retaining ribbon is bent 180 degrees with respect to the deflection ribbon to form a generally U-shaped bend to thereby establish a predetermined spacing between the ribbons and to also cause these ribbons to remain parallel to each other.
  • FIG. 1 is an enlarged elevational view of the steerable guidewire with a deflectable tip and control handle in accordance with the one aspect of the present invention
  • FIG. 2 is an enlarged sectional view showing the distal end of the steerable guidewire in its normal pre-shaped position
  • FIG. 3 is an enlarged sectional view showing the distal end of the steerable guidewire of FIG. 2 taken along the line 3 - 3 ;
  • FIG. 4 is a partially sectional view showing the control handle for the steerable guidewire.
  • FIGS. 5 and 5 A are sectional views showing the steerable guidewire deflected from its normal position to opposite extremes of deflection.
  • FIG. 1 generally illustrates a steerable guidewire system 10 which embodies the present invention and comprises a steerable guidewire 12 coupled to a control handle 14 . More particularly, the steerable guidewire comprises an elongated hypotube 16 , a helical coil 18 attached to and extending from the distal end of the hypotube 16 .
  • the helical coil 18 is preferably formed from platinum tungsten with the proximal turns being wound such that adjacent turns of the proximal portion are in contact with each other.
  • this element may take the form of any flexible cylindrical member, such as for example a thin metallic tube with or without portions of the tube removed by, for example laser cutting, so as to form a very flexible cylindrical member.
  • An elongated deflection member 20 extends from the proximal end of the control handle through the hypotube 16 and through the helical coil 18 , and is connected into an attachment member, or rounded bead 22 , which is disposed at the distal tip of the helical coil 18 .
  • a retaining ribbon 24 is connected to the distal end of the hypotube 16 and is also connected to the rounded bead 22 .
  • the control handle 14 generally comprises a slidable control knob 26 which may be moved longitudinally with respect to the control handle.
  • the control handle 14 is coupled to the deflection member 20 .
  • the longitudinal movement of the slidable control knob 26 causes deflection of the distal tip of the guidewire in either an upward or downward direction.
  • FIGS. 2 and 3 illustrate in more detail the distal portion of the steerable guidewire 12 .
  • FIG. 3 is a view of the guidewire 12 shown in FIG. 2 with the guidewire being rotated 90 degrees about its longitudinal axis.
  • the proximal end of the helical coil 18 is bonded, preferably by use of an epoxy, to the outer surface near the distal end of the hypotube 16 .
  • the elongated deflection member 20 takes the form of a small diameter cylindrical deflection member 20 having an intermediate portion which is flattened to form a thin deflection ribbon 34 having a thickness of approximately 0.002 inches.
  • the distal end of the cylindrical deflection member 20 is further flattened to a thickness of approximately 0.0015 inches and is bent back 180 degrees to form a U-shaped bend 26 a between the deflection ribbon 34 and the retaining ribbon 24 .
  • the proximal end of the retaining ribbon 24 is bonded, preferably by use of epoxy, to the outer surface of the distal end of the hypotube 16 .
  • the retaining ribbon 24 is aligned in a plane parallel to the plane of the deflection ribbon 34 and the U-shaped portion between the ribbons is encapsulated by the attachment member which preferably takes the form of a rounded epoxy bead 22 bonded to the distal tip of the helical coil 18 .
  • the retaining ribbon 24 is preferably attached to the rounded bead 22 at a position offset from the center of the bead in the same direction that the retaining ribbon 24 is offset from the longitudinal axis of the steerable guidewire 12 .
  • the deflection ribbon 34 is attached to the bead at a position offset from the center of the bead in an opposite direction from the offset of the retaining ribbon 24 .
  • the deflection ribbon 34 and the retaining ribbon 24 are pre-shaped into an arcuate, or curved, configuration to thereby maintain the helical coil 18 in a normally curved configuration.
  • the ribbons 24 , 34 are pre-shaped such that the distal tip of the guidewire curves away from the longitudinal axis of the guidewire in a direction toward that side of the guidewire containing the retaining ribbon 24 .
  • FIG. 4 illustrates in more detail the control handle 14 which includes a cylindrical body portion 38 with the slidable control knob 26 being mounted for longitudinal movement along the cylindrical body portion 38 of the control handle 14 .
  • the pair of set screws 28 , 30 extend through the slidable control knob 26 and lock onto the elongated deflection member 20 which extends through the control handle 14 .
  • the control handle 14 includes a coaxial hypotube 40 which is disposed about the deflection member 20 and which is locked in place within the control handle by another set of set screws 32 , 33 .
  • the coaxial hypotube 40 serves to prevent the deflection member 20 from buckling as the slidable control knob is moved in a distal direction.
  • the control handle 14 includes a pin vise 36 which serves to clamp onto the deflection member 20 .
  • the distal tip of the steerable guidewire 12 is normally biased into a downwardly curved position as illustrated in FIG. 2 because of the curve of the pre-shaped deflection ribbon 34 and the retaining ribbon 24 .
  • the deflection member 20 will be moved distally thereby causing the deflection ribbon 34 to move in a distal direction.
  • a force is applied to the top portion of the rounded bead 22 .
  • the retaining ribbon 24 is attached to the lower portion of the bead 22 to thereby maintain the bead at a fixed distance from the distal end of the hypotube 16 .
  • the tip of the guidewire is caused to deflect downwardly to a maximum position of deflection as shown in FIG. 5A . Since the deflection ribbon 34 and the retaining ribbon 24 are pre-shaped prior to any activation of the steerable guidewire, the amount of force required to deflect the guidewire in this direction is very small thereby preventing buckling of the deflection ribbon 34 as the deflection ribbon is pushed distally. As the deflection ribbon 34 is moved distally, the upper turns of the helical coil become slightly stretched and the lower turns of the coil become slightly compressed.
  • the deflection member 20 has a diameter of about 0.0065 inches and the deflection ribbon has a thickness of about 0.002 inches to thereby provide sufficient stiffness to prevent the buckling of these elements when the deflection member 20 is pushed distally. This construction also provides sufficient stiffness to transmit the necessary force to the distal tip of the guidewire.
  • the deflection member 20 When the slidable control knob 26 is moved in a proximal direction (to the left in FIG. 4 ) the deflection member 20 will be pulled to the left to thereby cause the deflection ribbon 34 to pull on the top portion of the bead 22 . Since again the retaining ribbon 24 causes the lower portion of the bead to remain at a fixed distance from the distal end of the hypotube 16 , the tip of the guidewire 12 is caused to bend in an upward direction to a maximum deflection as shown in FIG. 5 . Since the deflection ribbon 34 is in tension when the deflection member 20 is pulled, there is no concern for buckling of the deflection ribbon 34 . As the deflection ribbon 34 is moved proximally as shown in FIG. 5 , the upper coil turns become slightly compressed and the lower coil turns become somewhat stretched.
  • the elongated deflection member 20 , retaining ribbon 24 and deflection ribbon 34 are constructed of nitinol, but these elements may be formed from other flexible materials including polymers.
  • the helical coil 18 preferably has an outside coil diameter of about 0.013 inches and is constructed from an alloy comprised of about 92 percent platinum and 8 percent tungsten, but this element may also be constructed from numerous other materials. It is desirable that the coil exhibit the characteristic of being radiopaque to X-rays to assist in the positioning of the distal tip of the steerable guidewire 12 .
  • the deflection member 20 is formed from a single cylindrical nitinol wire of about 0.0065 inches in diameter having an intermediate portion which is flattened to form the deflection ribbon 34 with a thickness of about 0.002 inches, and a distal portion which is flattened to form the retaining ribbon 24 with a thickness of about 0.0015 inches.
  • the retaining ribbon 24 is bent back 180 degrees to form a generally U-shaped bend, which is subsequently encapsulated within the rounded bead 22 .
  • the rounded bead 22 is preferably formed with epoxy, but may be formed with soldering or by welding.
  • the helical coil 18 is preferably coated with an elastomeric polymer 41 on its distal end to act as a sealant preventing the entry of blood and contrast media into the guidewire and a fluorinated polymer 39 , such as Teflon, on its proximal end for lubrication purposes.
  • the guidewire as disclosed may be very easily and very precisely deflected in either of two directions for very precise steering of the guidewire through the vessels of the body.
  • the disclosed guidewire may be used for placement of a catheter within the vasculature of the human body, it may be used by itself to cross an obstruction within the vessels or it may be used to carry a therapeutic device mounted on the distal end of the guidewire for purposes of removing obstructions which may exist within a vessel of the body.

Abstract

A bi-directional steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and a spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip.

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • This patent application is a divisional patent application of U.S. patent application Ser. No. 10/224,168, filed on Aug. 20, 2002, entitled “Guidewire With Deflectable Tip”, which claims benefit of provisional patent application, U.S. Ser. No. 60/366,739 filed on Mar. 22, 2002.
  • BACKGROUND OF THE INVENTION
  • 1. Field of the Invention
  • The present invention relates to a steerable guidewire, and more particularly to a bi-directional steerable guidewire having a tip which may be very precisely “steered,” or deflected. The guidewire is particularly suitable for use in conjunction with the insertion of a catheter into a vessel of the body, or alternatively, the guidewire may be used by itself to open obstructions within a vessel or to carry a therapeutic device for removing obstructions within a vessel.
  • 2. Description of the Prior Art
  • For many years guidewires have included a core wire with the distal end being tapered and with a coil spring mounted on the tapered distal end. These guidewires have been used to facilitate the insertion of a catheter into a vessel of the body. Generally, the guidewire is inserted into a vessel, a catheter is inserted over the guidewire and the catheter is then moved through the vessel until the distal end of the catheter is positioned at a desired location. The guidewire is then retracted from the catheter and the catheter is left in the vessel. Alternatively, the guidewire may be first inserted into the catheter with the distal portion of the guidewire extending beyond the distal end of the catheter. This assembly is then inserted into a vessel with the distal tip of the guidewire being used to facilitate movement of the guidewire and catheter through the vessel. Again, when the distal tip of the catheter has been placed in a desired location, the guidewire may be retracted thereby leaving the catheter in place within the vessel.
  • Another common application for guidewires is that of using the distal tip of the guidewire for removing an obstruction within a vessel. Often times this procedure is accomplished by inserting the guidewire within a vessel, moving the distal tip of the guidewire into contact with the obstruction and then very gently tapping the distal tip of the guidewire against the obstruction until the guidewire passes through the obstruction. Alternatively, various types of devices may be placed on the distal end of a guidewire for actively opening an obstruction within the vessel. Examples of such devices which may be placed on the end of the guidewires are disclosed in the following United States patents to Robert C. Stevens: U.S. Pat. Nos. 5,116,350; 5,078,722; 4,936,845; 4,923,462; and, 4,854,325.
  • While most guidewires used today do not include a mechanism for deflecting or steering the tip of the guidewire, it is very desirable to provide tip steering in order to facilitate movement of the guidewire through the tortuous vessels of the body. There are many patents directed toward different mechanisms for deflecting the distal tip of a guidewire in order to steer the guidewire. Examples of such guidewires are disclosed in the following patents: U.S. Pat. No. 4,815,478 to Maurice Buchbinder, et al., U.S. Pat. No. 4,813,434 to Maurice Buchbinder, et al., U.S. Pat. No. 5,037,391 to Julius G. Hammerslag, et al., U.S. Pat. No. 5,203,772 to Gary R. Hammerslag, et al., U.S. Pat. No. 6,146,338 to Kenneth C. Gardeski, et al., U.S. Pat. No. 6,126,649 to Robert A. VanTassel, et al., U.S. Pat. No. 6,059,739 to James C. Baumann and U.S. Pat. No. 5,372,587 to Julius G. Hammerslag, et al. U.S. Pat. No. 4,940,062 to Hilary J. Hampton, et al., discloses a balloon catheter having a steerable tip section. All of the above-identified patents are incorporated herein by reference.
  • While each of the latter group of patents disclose guidewires having some degree of steerability, there is a need to have a guidewire with very precise steering in a guidewire of a very small diameter which is suitable for the purposes described above. More particularly, there is an important need for a very small diameter guidewire having a distal tip which may be deflected very precisely in either of two directions to enhance steerability and which is suitable for vascular applications.
  • SUMMARY OF THE INVENTION
  • In accordance with one aspect of the present invention, there is provided a very small diameter steerable guidewire having a deflectable tip which includes an elongated flexible tubing, a flexible helical coil attached to the distal portion of the flexible tubing, an elongated deflection member which is slidably disposed within the tubing and within the helical coil. The proximal portion of the deflection member is of a cylindrical configuration and the distal portion is tapered to form a deflection ribbon. Alternatively, the deflection member may take the form of a proximal cylindrical wire which is attached at its distal end to a deflection ribbon. In addition, a retaining ribbon is attached to the distal end of the flexible tubing and is oriented to extend in a plane which is generally parallel to the plane of the ribbon portion of the deflection member. An attachment member which may take the form of a rounded bead, preferably formed from epoxy, is bonded to the distal end of the helical coil, the distal end of the deflection ribbon and the distal end of the retaining ribbon so that longitudinal movement of the deflection member causes the distal end of the helical coil to be deflected.
  • In accordance with another aspect of the present invention, the retaining ribbon and the deflection ribbon are preferably pre-shaped into a curved configuration to thereby cause the flexible helical coil to be biased into a normally curved shape.
  • In accordance with a further aspect of the present invention, the distal portion of the deflection ribbon engages the attachment member, or rounded bead, at a location offset from the center of the attachment member, and the distal portion of the retaining ribbon engages the attachment member at a location offset from the center of the attachment member. Preferably, the retaining ribbon engages the attachment member at a location offset from the center portion of the attachment member in the opposite direction from the offset location of the deflection ribbon.
  • In accordance with still another aspect of the present invention, the deflection ribbon and the retaining ribbon are connected to each other within the attachment member. Preferably these two elements are formed as a single unitary element. In a preferred embodiment of the invention the cylindrical deflection member is flattened to form the deflection ribbon and is further flattened at its distal end to form the retaining ribbon. The retaining ribbon is bent 180 degrees with respect to the deflection ribbon to form a generally U-shaped bend to thereby establish a predetermined spacing between the ribbons and to also cause these ribbons to remain parallel to each other.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is an enlarged elevational view of the steerable guidewire with a deflectable tip and control handle in accordance with the one aspect of the present invention;
  • FIG. 2 is an enlarged sectional view showing the distal end of the steerable guidewire in its normal pre-shaped position;
  • FIG. 3 is an enlarged sectional view showing the distal end of the steerable guidewire of FIG. 2 taken along the line 3-3;
  • FIG. 4 is a partially sectional view showing the control handle for the steerable guidewire; and,
  • FIGS. 5 and 5A are sectional views showing the steerable guidewire deflected from its normal position to opposite extremes of deflection.
  • DESCRIPTION OF THE PREFERRED EMBODIMENT
  • FIG. 1 generally illustrates a steerable guidewire system 10 which embodies the present invention and comprises a steerable guidewire 12 coupled to a control handle 14. More particularly, the steerable guidewire comprises an elongated hypotube 16, a helical coil 18 attached to and extending from the distal end of the hypotube 16. The helical coil 18 is preferably formed from platinum tungsten with the proximal turns being wound such that adjacent turns of the proximal portion are in contact with each other.
  • While the preferred embodiment of the present invention includes the helical coil 18, this element may take the form of any flexible cylindrical member, such as for example a thin metallic tube with or without portions of the tube removed by, for example laser cutting, so as to form a very flexible cylindrical member. An elongated deflection member 20 extends from the proximal end of the control handle through the hypotube 16 and through the helical coil 18, and is connected into an attachment member, or rounded bead 22, which is disposed at the distal tip of the helical coil 18. In addition, a retaining ribbon 24 is connected to the distal end of the hypotube 16 and is also connected to the rounded bead 22.
  • The control handle 14 generally comprises a slidable control knob 26 which may be moved longitudinally with respect to the control handle. The control handle 14 is coupled to the deflection member 20. As will be discussed in more detail, the longitudinal movement of the slidable control knob 26 causes deflection of the distal tip of the guidewire in either an upward or downward direction.
  • FIGS. 2 and 3 illustrate in more detail the distal portion of the steerable guidewire 12. As may be appreciated, FIG. 3 is a view of the guidewire 12 shown in FIG. 2 with the guidewire being rotated 90 degrees about its longitudinal axis. More particularly, the proximal end of the helical coil 18 is bonded, preferably by use of an epoxy, to the outer surface near the distal end of the hypotube 16. The elongated deflection member 20 takes the form of a small diameter cylindrical deflection member 20 having an intermediate portion which is flattened to form a thin deflection ribbon 34 having a thickness of approximately 0.002 inches. The distal end of the cylindrical deflection member 20 is further flattened to a thickness of approximately 0.0015 inches and is bent back 180 degrees to form a U-shaped bend 26 a between the deflection ribbon 34 and the retaining ribbon 24. The proximal end of the retaining ribbon 24 is bonded, preferably by use of epoxy, to the outer surface of the distal end of the hypotube 16. The retaining ribbon 24 is aligned in a plane parallel to the plane of the deflection ribbon 34 and the U-shaped portion between the ribbons is encapsulated by the attachment member which preferably takes the form of a rounded epoxy bead 22 bonded to the distal tip of the helical coil 18.
  • As may be appreciated, with this unitary construction of the ribbon members, these members remain aligned so that both lie in planes parallel to each other. In addition, the U-shaped bend portion when encapsulated into the rounded bead 22 causes the retaining ribbon and deflection ribbon to be properly spaced with respect to each other.
  • As illustrated in FIG. 2, the retaining ribbon 24 is preferably attached to the rounded bead 22 at a position offset from the center of the bead in the same direction that the retaining ribbon 24 is offset from the longitudinal axis of the steerable guidewire 12. In addition, the deflection ribbon 34 is attached to the bead at a position offset from the center of the bead in an opposite direction from the offset of the retaining ribbon 24.
  • Also, as may be seen in FIG. 2, the deflection ribbon 34 and the retaining ribbon 24 are pre-shaped into an arcuate, or curved, configuration to thereby maintain the helical coil 18 in a normally curved configuration. The ribbons 24, 34 are pre-shaped such that the distal tip of the guidewire curves away from the longitudinal axis of the guidewire in a direction toward that side of the guidewire containing the retaining ribbon 24.
  • FIG. 4 illustrates in more detail the control handle 14 which includes a cylindrical body portion 38 with the slidable control knob 26 being mounted for longitudinal movement along the cylindrical body portion 38 of the control handle 14. The pair of set screws 28, 30 extend through the slidable control knob 26 and lock onto the elongated deflection member 20 which extends through the control handle 14. In addition, the control handle 14 includes a coaxial hypotube 40 which is disposed about the deflection member 20 and which is locked in place within the control handle by another set of set screws 32, 33. The coaxial hypotube 40 serves to prevent the deflection member 20 from buckling as the slidable control knob is moved in a distal direction. Still further, the control handle 14 includes a pin vise 36 which serves to clamp onto the deflection member 20.
  • In operation, as previously described, the distal tip of the steerable guidewire 12 is normally biased into a downwardly curved position as illustrated in FIG. 2 because of the curve of the pre-shaped deflection ribbon 34 and the retaining ribbon 24. When the slidable control knob 26 is moved distally, the deflection member 20 will be moved distally thereby causing the deflection ribbon 34 to move in a distal direction. As the deflection ribbon is moved distally, a force is applied to the top portion of the rounded bead 22. The retaining ribbon 24 is attached to the lower portion of the bead 22 to thereby maintain the bead at a fixed distance from the distal end of the hypotube 16. As the deflection ribbon 34 is moved to the right, the tip of the guidewire is caused to deflect downwardly to a maximum position of deflection as shown in FIG. 5A. Since the deflection ribbon 34 and the retaining ribbon 24 are pre-shaped prior to any activation of the steerable guidewire, the amount of force required to deflect the guidewire in this direction is very small thereby preventing buckling of the deflection ribbon 34 as the deflection ribbon is pushed distally. As the deflection ribbon 34 is moved distally, the upper turns of the helical coil become slightly stretched and the lower turns of the coil become slightly compressed. The deflection member 20 has a diameter of about 0.0065 inches and the deflection ribbon has a thickness of about 0.002 inches to thereby provide sufficient stiffness to prevent the buckling of these elements when the deflection member 20 is pushed distally. This construction also provides sufficient stiffness to transmit the necessary force to the distal tip of the guidewire.
  • When the slidable control knob 26 is moved in a proximal direction (to the left in FIG. 4) the deflection member 20 will be pulled to the left to thereby cause the deflection ribbon 34 to pull on the top portion of the bead 22. Since again the retaining ribbon 24 causes the lower portion of the bead to remain at a fixed distance from the distal end of the hypotube 16, the tip of the guidewire 12 is caused to bend in an upward direction to a maximum deflection as shown in FIG. 5. Since the deflection ribbon 34 is in tension when the deflection member 20 is pulled, there is no concern for buckling of the deflection ribbon 34. As the deflection ribbon 34 is moved proximally as shown in FIG. 5, the upper coil turns become slightly compressed and the lower coil turns become somewhat stretched.
  • In a preferred embodiment of the present invention, the elongated deflection member 20, retaining ribbon 24 and deflection ribbon 34 are constructed of nitinol, but these elements may be formed from other flexible materials including polymers. The helical coil 18 preferably has an outside coil diameter of about 0.013 inches and is constructed from an alloy comprised of about 92 percent platinum and 8 percent tungsten, but this element may also be constructed from numerous other materials. It is desirable that the coil exhibit the characteristic of being radiopaque to X-rays to assist in the positioning of the distal tip of the steerable guidewire 12. The deflection member 20 is formed from a single cylindrical nitinol wire of about 0.0065 inches in diameter having an intermediate portion which is flattened to form the deflection ribbon 34 with a thickness of about 0.002 inches, and a distal portion which is flattened to form the retaining ribbon 24 with a thickness of about 0.0015 inches. The retaining ribbon 24 is bent back 180 degrees to form a generally U-shaped bend, which is subsequently encapsulated within the rounded bead 22. The rounded bead 22 is preferably formed with epoxy, but may be formed with soldering or by welding.
  • It has been found that the addition of graphite between the deflection member 20 and deflection ribbon 34, and the inner lumen of the hypotube 16 provides lubrication. Other lubricants, such as Teflon or MDX may be used for this purpose. The helical coil 18 is preferably coated with an elastomeric polymer 41 on its distal end to act as a sealant preventing the entry of blood and contrast media into the guidewire and a fluorinated polymer 39, such as Teflon, on its proximal end for lubrication purposes.
  • It may be seen that the guidewire as disclosed may be very easily and very precisely deflected in either of two directions for very precise steering of the guidewire through the vessels of the body. As may be apparent, the disclosed guidewire may be used for placement of a catheter within the vasculature of the human body, it may be used by itself to cross an obstruction within the vessels or it may be used to carry a therapeutic device mounted on the distal end of the guidewire for purposes of removing obstructions which may exist within a vessel of the body.
  • The preceding specific embodiment is illustrated of the practice of this invention. It is to be understood, however, that other variations may also be employed without departing from the spirit and scope of the invention as hereinafter claimed.

Claims (20)

1. A bi-directional steerable guidewire having a deflectable tip which comprises:
an elongated flexible tubing having proximal and distal portions;
a flexible helical coil having proximal and distal ends, the proximal end of said helical coil is attached to the distal portion of the flexible tubing;
an elongated deflection member having proximal and distal portions and being slidably disposed within said tubing and within said helical coil, the distal portion of said deflection member being flattened to form a deflection ribbon which extends in a plane;
a retaining ribbon having proximal and distal ends, the proximal end of the retaining ribbon is attached to the distal portion of the flexible tubing and the retaining ribbon is oriented to extend in a plane which is generally parallel to the plane of the deflection ribbon; and,
an attachment member engaging the distal end of the helical coil, the distal portion of the deflection member and the distal end of the retaining ribbon so that longitudinal movement of the deflection member in a distal direction causes the distal end of the helical coil to be deflected in one direction and longitudinal movement of the deflection member in a proximal direction causes the distal end of the helical coil to deflect in another opposite direction.
2. A steerable guidewire as defined in claim 1, wherein the retaining ribbon and the deflection ribbon are normally biased in an arcuate configuration to thereby cause the distal end of the helical coil to be normally biased in a curved shape.
3. A steerable guidewire as defined in claim 1, wherein the proximal portion of said deflection member is of a circular cross section which extends from the proximal portion of the flexible tubing to approximately the distal portion of the tubing.
4. A steerable guidewire as defined in claim 3, wherein the proximal end of said retaining ribbon extends from the distal portion of the flexible tubing to approximately the distal end of the flexible helical coil.
5. A steerable guidewire as defined in claim 1, wherein the attachment member takes the form of a rounded bead.
6. A steerable guidewire as defined in claim 5, wherein the rounded bead is formed with an epoxy material.
7. A steerable guidewire as defined in claim 1, wherein the attachment member takes the form of a rounded bead which contacts the distal end of the helical coil to define a circular surface at the distal end of the coil and the deflection ribbon engages the rounded bead at a location offset from the center of the circular surface of the rounded bead.
8. A steerable guidewire as defined in claim 7, wherein the distal end of the retaining ribbon engages the rounded bead at a location offset from the center of the circular surface of the rounded bead.
9. A bidirectional steerable guidewire having a deflectable tip which comprises:
an elongated flexible tubing having proximal and distal portions;
a flexible helical coil having proximal and distal ends, the proximal end of said helical coil is attached to the distal portion of the flexible tubing;
an elongated deflection member having proximal and distal portions and being slidably disposed within said tubing and within said helical coil, the distal portion of said deflection member being tapered;
an elongated retaining member having proximal and distal ends, the proximal end of the retaining member is attached to the distal portion of the flexible tubing; and,
an attachment member engaging the distal end of the helical coil, the deflection member and the distal end of the retaining member so that longitudinal movement of the deflection member in a distal direction causes the distal end of the helical coil to be deflected in one direction and longitudinal movement of the deflection member in a proximal direction causes the distal end of the helical coil to deflect in an opposite direction.
10. A steerable guidewire as defined in claim 9, wherein the retaining member is pre-shaped in an arcuate configuration to thereby cause the flexible helical coil to be normally biased into a curved shape.
11. A steerable guidewire as defined in claim 10, wherein the attachment member takes the form of a rounded bead.
12. A steerable guidewire having a deflectable tip which comprises:
an elongated flexible tubing having proximal and distal portions;
a flexible helical coil having proximal and distal ends, the proximal end of said helical coil is attached to the distal portion of the flexible tubing;
an elongated deflection member comprised of proximal and distal portions and being slidably disposed within said tubing and within said helical coil, the proximal portion of the deflection member being of a cylindrical cross section and the distal portion of said deflection member takes the form a deflection ribbon which extends in a plane;
a retaining ribbon having proximal and distal ends, the proximal end of the retaining ribbon is attached to the distal portion of the flexible tubing and the retaining ribbon is oriented to extend in a plane which is generally parallel to the plane of the deflection ribbon; and,
an attachment member engaging the distal end of the helical coil, the distal portion of the deflection member and the distal end of the retaining ribbon so that longitudinal movement of the deflection member in a distal direction causes the distal end of the helical coil to be deflected in one direction and longitudinal movement of the deflection member in a proximal direction causes the distal end of the helical coil to deflect in another opposite direction.
13. A steerable guidewire as defined in claim 12, wherein the retaining ribbon and the deflection ribbon are normally biased in an arcuate configuration to thereby cause the distal end of the helical coil to be normally biased in a curved shape.
14. A steerable guidewire as defined in claim 12, wherein the distal portion of the deflection member and the deflection ribbon are formed from a wire of a circular cross section and in which the distal portion is flattened to form the deflection ribbon.
15. A steerable guidewire as defined in claim 12, wherein the proximal portion of the elongated flexible tubing is coupled to a control handle and the elongated deflection member is mounted with the control handle for longitudinal movement.
16. A steerable guidewire as defined in claim 15, wherein said control handle includes a movable knob which is coupled to the elongated deflection member for longitudinal positioning of the deflection member.
17. A bi-directional steerable guidewire having a deflectable tip which comprises:
an elongated flexible tubing having proximal and distal portions;
a flexible cylindrical member having proximal and distal ends, the proximal end of said cylindrical member is attached to the distal portion of the flexible tubing;
an elongated deflection member having proximal and distal portions and being slidably disposed within said tubing and within said cylindrical member, the distal portion of said deflection member being tapered;
an elongated retaining member having proximal and distal ends, the proximal end of the retaining member is attached to the distal portion of the flexible tubing; and,
an attachment member engaging the distal end of the cylindrical member, the deflection member and the distal end of the retaining member so that longitudinal movement of the deflection member in a distal direction causes the distal end of the cylindrical member to be deflected in one direction and longitudinal movement of the deflection member in a proximal direction causes the distal end of the cylindrical member to deflect in an opposite direction.
18. A steerable guidewire as defined in claim 17, wherein the retaining member is pre-shaped in an arcuate configuration to thereby cause the flexible cylindrical member to be normally biased into a curved shape.
19. A steerable guidewire as defined in claim 18, wherein the distal portion of the elongated deflection member takes the form of a thin ribbon which extends in a plane, and said retaining member takes the form of a thin ribbon which is oriented to extend in a plane which is generally parallel to the plane of the deflection ribbon.
20. A steerable guidewire as defined in claim 19, wherein the attachment member takes the form of a rounded bead.
US11/473,764 2002-03-22 2006-06-23 Guidewire with deflectable tip Abandoned US20060241519A1 (en)

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US10/224,168 US7128718B2 (en) 2002-03-22 2002-08-20 Guidewire with deflectable tip
US11/473,764 US20060241519A1 (en) 2002-03-22 2006-06-23 Guidewire with deflectable tip

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Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070213689A1 (en) * 2002-03-22 2007-09-13 Grewe David D Deflectable tip infusion guidewire
US20080255446A1 (en) * 2007-04-16 2008-10-16 General Electric Company System and method of integrating electromagnetic microsensors in guidewires
WO2009029430A1 (en) * 2007-08-31 2009-03-05 Revascular Therapeutics, Inc. Guidewire for crossing occlusions or stenoses having a shapeable distal end
US20090326368A1 (en) * 2008-06-30 2009-12-31 General Electric Company System and Method For Integrating Electromagnetic Microsensors in Guidewires
US8043314B2 (en) 2000-04-06 2011-10-25 Revascular Therapeutics Inc. Guidewire for crossing occlusions or stenoses
US8162891B2 (en) 2008-11-26 2012-04-24 Revascular Therapeutics, Inc. Delivery and exchange catheter for storing guidewire
US20120197159A1 (en) * 2011-01-28 2012-08-02 Asahi Intecc Co., Ltd. Guidewire
US20130006149A1 (en) * 2011-06-29 2013-01-03 Abbott Cardiovascular Systems Guide Wire Device Including a Solderable Linear Elastic Nickel-Titanium Distal End Section and Methods Of Preparation Therefor
US8986225B2 (en) 2012-08-02 2015-03-24 Covidien Lp Guidewire
WO2018017351A1 (en) * 2016-07-18 2018-01-25 Scientia Vascular, Llc Guidewire devices having shapeable polymer tips
US9950137B2 (en) 2009-04-03 2018-04-24 Scientia Vascular, Llc Micro-fabricated guidewire devices formed with hybrid materials
US10232141B2 (en) 2008-12-08 2019-03-19 Scientia Vascular, Llc Micro-cutting systems for forming cuts in products
WO2019081962A1 (en) 2017-10-24 2019-05-02 Ecole Polytechnique Federale De Lausanne (Epfl) Steerable device and system
US10363389B2 (en) 2009-04-03 2019-07-30 Scientia Vascular, Llc Micro-fabricated guidewire devices having varying diameters
WO2020217171A1 (en) 2019-04-24 2020-10-29 Ecole Polytechnique Federale De Lausanne (Epfl) Enhanced torque steerable guidewire
US10821268B2 (en) 2016-09-14 2020-11-03 Scientia Vascular, Llc Integrated coil vascular devices
US11052228B2 (en) 2016-07-18 2021-07-06 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US11305095B2 (en) 2018-02-22 2022-04-19 Scientia Vascular, Llc Microfabricated catheter having an intermediate preferred bending section
US11369351B2 (en) 2017-05-26 2022-06-28 Scientia Vascular, Inc. Micro-fabricated medical device having a non-helical cut arrangement
US11406791B2 (en) 2009-04-03 2022-08-09 Scientia Vascular, Inc. Micro-fabricated guidewire devices having varying diameters
US11452541B2 (en) 2016-12-22 2022-09-27 Scientia Vascular, Inc. Intravascular device having a selectively deflectable tip
US11779477B2 (en) 2010-11-17 2023-10-10 Abbott Cardiovascular Systems, Inc. Radiopaque intraluminal stents

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10105592A1 (en) 2001-02-06 2002-08-08 Achim Goepferich Placeholder for drug release in the frontal sinus
US7520863B2 (en) * 2002-03-22 2009-04-21 Cordis Corporation Guidewire with deflectable tip having improved torque characteristics
US7351214B2 (en) 2002-03-22 2008-04-01 Cordis Corporation Steerable balloon catheter
US8317816B2 (en) 2002-09-30 2012-11-27 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
US7758592B2 (en) 2002-12-02 2010-07-20 Wilson-Cook Medical Inc. Loop tip wire guide
DE602004027050D1 (en) * 2003-08-07 2010-06-17 Brivant Res & Dev Ltd GUIDE WIRE FOR A CATHETER
US7615032B2 (en) * 2004-03-24 2009-11-10 Windcrest Llc Vascular guidewire control apparatus
AU2005229058A1 (en) * 2004-03-24 2005-10-13 Windcrest Llc Energizer for vascular guidewire
US10188413B1 (en) 2004-04-21 2019-01-29 Acclarent, Inc. Deflectable guide catheters and related methods
US8146400B2 (en) 2004-04-21 2012-04-03 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US20070167682A1 (en) 2004-04-21 2007-07-19 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US20060004323A1 (en) 2004-04-21 2006-01-05 Exploramed Nc1, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US20060063973A1 (en) 2004-04-21 2006-03-23 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US7361168B2 (en) 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US7419497B2 (en) 2004-04-21 2008-09-02 Acclarent, Inc. Methods for treating ethmoid disease
US7462175B2 (en) 2004-04-21 2008-12-09 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8864787B2 (en) 2004-04-21 2014-10-21 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US20190314620A1 (en) 2004-04-21 2019-10-17 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US9554691B2 (en) 2004-04-21 2017-01-31 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US9101384B2 (en) 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US7410480B2 (en) * 2004-04-21 2008-08-12 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US7559925B2 (en) 2006-09-15 2009-07-14 Acclarent Inc. Methods and devices for facilitating visualization in a surgical environment
US7720521B2 (en) * 2004-04-21 2010-05-18 Acclarent, Inc. Methods and devices for performing procedures within the ear, nose, throat and paranasal sinuses
US9089258B2 (en) 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US8764729B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US20070208252A1 (en) 2004-04-21 2007-09-06 Acclarent, Inc. Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
JP2005342470A (en) * 2004-06-03 2005-12-15 Ys Medical:Kk Medical guide wire
US20060047224A1 (en) * 2004-09-01 2006-03-02 Ryan Grandfield Polymer coated guide wire
US9655633B2 (en) 2004-09-10 2017-05-23 Penumbra, Inc. System and method for treating ischemic stroke
US8366735B2 (en) 2004-09-10 2013-02-05 Penumbra, Inc. System and method for treating ischemic stroke
US20060058837A1 (en) * 2004-09-10 2006-03-16 Arani Bose System and method for treating ischemic stroke
ATE419892T1 (en) 2004-09-30 2009-01-15 Wilson Cook Medical Inc LOOP TYPE CONTROLLABLE GUIDE WIRE
US8070693B2 (en) * 2004-09-30 2011-12-06 Cook Medical Technologies Llc Articulating steerable wire guide
US7989042B2 (en) * 2004-11-24 2011-08-02 Boston Scientific Scimed, Inc. Medical devices with highly flexible coated hypotube
US8147481B2 (en) * 2005-03-24 2012-04-03 The Cleveland Clinic Foundation Vascular guidewire control apparatus
US7553305B2 (en) * 2005-06-09 2009-06-30 Enpath Medical, Inc. Push-pull wire anchor
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US8267872B2 (en) * 2005-07-07 2012-09-18 St. Jude Medical, Cardiology Division, Inc. Steerable guide wire with torsionally stable tip
US20070185415A1 (en) * 2005-07-07 2007-08-09 Ressemann Thomas V Steerable guide wire with torsionally stable tip
US8114113B2 (en) 2005-09-23 2012-02-14 Acclarent, Inc. Multi-conduit balloon catheter
US7771388B2 (en) 2005-10-12 2010-08-10 Daniel Olsen Steerable catheter system
CA2628417C (en) * 2005-11-08 2014-07-08 Custom Medical Applications, Inc. Reinforced catheter with articulated distal tip
EP1951350B1 (en) * 2005-11-21 2014-05-07 Cook Medical Technologies LLC Articulating steerable wire guide
US8190389B2 (en) 2006-05-17 2012-05-29 Acclarent, Inc. Adapter for attaching electromagnetic image guidance components to a medical device
US8715205B2 (en) 2006-08-25 2014-05-06 Cook Medical Tecnologies Llc Loop tip wire guide
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device
US8439687B1 (en) 2006-12-29 2013-05-14 Acclarent, Inc. Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices
IL181489A0 (en) * 2007-02-21 2007-07-04 Ovalum Ltd Deformation of the distal portion of a guidewire
US8852223B2 (en) * 2007-04-06 2014-10-07 Cordis Corporation Fixed wire dilatation catheter with an elongateable distal end
US8118757B2 (en) 2007-04-30 2012-02-21 Acclarent, Inc. Methods and devices for ostium measurement
US8485199B2 (en) 2007-05-08 2013-07-16 Acclarent, Inc. Methods and devices for protecting nasal turbinate during surgery
US20090076416A1 (en) * 2007-09-17 2009-03-19 Medtronic Vascular, Inc. Guidewire with Adjustable Core
US10206821B2 (en) 2007-12-20 2019-02-19 Acclarent, Inc. Eustachian tube dilation balloon with ventilation path
US7871414B2 (en) 2007-12-28 2011-01-18 Wilson-Cook Medical Inc. Loop tip wire guide with outer sleeve
US8182432B2 (en) 2008-03-10 2012-05-22 Acclarent, Inc. Corewire design and construction for medical devices
US20100022989A1 (en) * 2008-07-25 2010-01-28 Parasmo Ronald S Steerable catheter and method of making the same
JP5676446B2 (en) 2008-07-30 2015-02-25 アクラレント インコーポレイテッド Sinus mouth finder
US20100049136A1 (en) * 2008-08-19 2010-02-25 Cook Incorporated Guide Wire and Method of Use Thereof
AU2009293312B2 (en) 2008-09-18 2015-07-09 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US8460214B2 (en) * 2008-10-14 2013-06-11 The Cleveland Clinic Foundation Vascular guidewire system and method
US20100241155A1 (en) 2009-03-20 2010-09-23 Acclarent, Inc. Guide system with suction
US8435290B2 (en) 2009-03-31 2013-05-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US7978742B1 (en) 2010-03-24 2011-07-12 Corning Incorporated Methods for operating diode lasers
RU2629901C2 (en) * 2009-09-22 2017-09-04 Адем Systems and methods of impedance measurement for determining components of solid and fluid objects
US20110190831A1 (en) * 2010-01-29 2011-08-04 Kyphon Sarl Steerable balloon catheter
WO2011156688A2 (en) 2010-06-10 2011-12-15 Windcrest Llc Guidewire control device
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
US9528814B2 (en) 2011-05-19 2016-12-27 NeoVision, LLC Apparatus and method of using impedance resonance sensor for thickness measurement
US9465089B2 (en) 2011-12-01 2016-10-11 Neovision Llc NMR spectroscopy device based on resonance type impedance (IR) sensor and method of NMR spectra acquisition
US8952708B2 (en) 2011-12-02 2015-02-10 Neovision Llc Impedance resonance sensor for real time monitoring of different processes and methods of using same
WO2014066439A1 (en) 2012-10-22 2014-05-01 Medtronic Ardian Luxembourg Sarl Catheters with enhanced flexibility
US9044575B2 (en) 2012-10-22 2015-06-02 Medtronic Adrian Luxembourg S.a.r.l. Catheters with enhanced flexibility and associated devices, systems, and methods
US9233225B2 (en) * 2012-11-10 2016-01-12 Curvo Medical, Inc. Coaxial bi-directional catheter
US9549666B2 (en) 2012-11-10 2017-01-24 Curvo Medical, Inc. Coaxial micro-endoscope
US9629684B2 (en) 2013-03-15 2017-04-25 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US9066726B2 (en) 2013-03-15 2015-06-30 Medtronic Ardian Luxembourg S.A.R.L. Multi-electrode apposition judgment using pressure elements
US9433437B2 (en) 2013-03-15 2016-09-06 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
WO2014189794A1 (en) 2013-05-18 2014-11-27 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters with shafts for enhanced flexibility and control and associated devices, systems, and methods
EP3082932B1 (en) * 2013-12-19 2018-01-31 Bendit Technologies Ltd. Steering tool
US10391282B2 (en) 2014-07-08 2019-08-27 Teleflex Innovations S.À.R.L. Guidewires and methods for percutaneous occlusion crossing
US11389172B2 (en) 2016-09-29 2022-07-19 Rapid Medical Ltd. Rotationally torquable endovascular device with variable flexibility tip
CN106362264A (en) * 2016-09-30 2017-02-01 佛山市其右医疗科技有限公司 Controlled bending type PTCA guide wire
US10556287B2 (en) 2017-02-21 2020-02-11 Abbott Cardiovascular Systems Inc. Method for selectively pretinning a guidewire core
WO2019083757A1 (en) 2017-10-26 2019-05-02 Teleflex Innovations S.A.R.L. Subintimal catheter device and assembly
AU2018383108A1 (en) 2017-12-12 2020-06-25 Rapid Medical Ltd. Guide wire activation mechanism and proximal actuation mechanism
CN108452394B (en) * 2018-03-14 2020-05-19 河南科技大学第一附属医院 Urinary surgery operation is with catheterization device
EP3815732B1 (en) * 2018-06-29 2023-01-25 Asahi Intecc Co., Ltd. Guide wire
US11413174B2 (en) 2019-06-26 2022-08-16 Covidien Lp Core assembly for medical device delivery systems
US11154692B2 (en) 2019-10-30 2021-10-26 Rapid Medical Ltd. Intraluminal device with looped core wire
US11872357B2 (en) 2020-11-09 2024-01-16 Agile Devices, Inc. Devices for steering catheters
WO2022159139A1 (en) * 2021-01-21 2022-07-28 Scientia Vascular, Llc High torque guidewire device
CN115463319B (en) * 2022-09-27 2023-08-01 广东博迈医疗科技股份有限公司 Scoring wire balloon dilation catheter

Citations (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US400369A (en) * 1889-03-26 Fence-making machine
US4665906A (en) * 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US4719924A (en) * 1986-09-09 1988-01-19 C. R. Bard, Inc. Small diameter steerable guidewire with adjustable tip
US4757827A (en) * 1987-02-17 1988-07-19 Versaflex Delivery Systems Inc. Steerable guidewire with deflectable tip
US4770188A (en) * 1979-06-30 1988-09-13 Machida Endoscope Co., Ltd. Guide tube assembly for an endoscope
US4813434A (en) * 1987-02-17 1989-03-21 Medtronic Versaflex, Inc. Steerable guidewire with deflectable tip
US4815478A (en) * 1987-02-17 1989-03-28 Medtronic Versaflex, Inc. Steerable guidewire with deflectable tip
US4827941A (en) * 1987-12-23 1989-05-09 Advanced Cardiovascular Systems, Inc. Extendable guidewire for cardiovascular procedures
US4854325A (en) * 1987-11-09 1989-08-08 Stevens Robert C Reciprocating guidewire method
US4875489A (en) * 1987-08-14 1989-10-24 Advanced Cardiovascular Systems, Inc. Extendable guidewire
US4881981A (en) * 1988-04-20 1989-11-21 Johnson Service Company Method for producing a shape memory alloy member having specific physical and mechanical properties
US4886067A (en) * 1989-01-03 1989-12-12 C. R. Bard, Inc. Steerable guidewire with soft adjustable tip
US4921482A (en) * 1989-01-09 1990-05-01 Hammerslag Julius G Steerable angioplasty device
US4923462A (en) * 1987-03-17 1990-05-08 Cordis Corporation Catheter system having a small diameter rotatable drive member
US4925445A (en) * 1983-09-16 1990-05-15 Fuji Terumo Co., Ltd. Guide wire for catheter
US4935088A (en) * 1987-12-04 1990-06-19 Masuhiro Mitsuyama Method of making a multi-pocketed paper holder
US4936845A (en) * 1987-03-17 1990-06-26 Cordis Corporation Catheter system having distal tip for opening obstructions
US4940062A (en) * 1988-05-26 1990-07-10 Advanced Cardiovascular Systems, Inc. Guiding member with deflectable tip
US4953553A (en) * 1989-05-11 1990-09-04 Advanced Cardiovascular Systems, Inc. Pressure monitoring guidewire with a flexible distal portion
US4966163A (en) * 1989-02-14 1990-10-30 Advanced Cardiovascular Systems, Inc. Extendable guidewire for vascular procedures
US4984581A (en) * 1988-10-12 1991-01-15 Flexmedics Corporation Flexible guide having two-way shape memory alloy
US4998916A (en) * 1989-01-09 1991-03-12 Hammerslag Julius G Steerable medical device
US5037391A (en) * 1989-01-09 1991-08-06 Pilot Cardiovascular Systems, Inc. Steerable angioplasty device
US5190050A (en) * 1991-11-08 1993-03-02 Electro-Catheter Corporation Tip deflectable steerable catheter
US5203772A (en) * 1989-01-09 1993-04-20 Pilot Cardiovascular Systems, Inc. Steerable medical device
US5242394A (en) * 1985-07-30 1993-09-07 Advanced Cardiovascular Systems, Inc. Steerable dilatation catheter
US5341818A (en) * 1992-12-22 1994-08-30 Advanced Cardiovascular Systems, Inc. Guidewire with superelastic distal portion
US5365942A (en) * 1990-06-04 1994-11-22 C. R. Bard, Inc. Guidewire tip construction
US5368049A (en) * 1991-05-21 1994-11-29 C. R. Bard, Inc. Superelastic formable guidewire with malleable cladding
US5372587A (en) * 1989-01-09 1994-12-13 Pilot Cariovascular Systems, Inc. Steerable medical device
US5397305A (en) * 1990-12-21 1995-03-14 Advanced Cardiovascular Systems, Inc. Fixed-wire dilatation catheter with rotatable balloon assembly
US5480382A (en) * 1989-01-09 1996-01-02 Pilot Cardiovascular Systems, Inc. Steerable medical device
US5501694A (en) * 1992-11-13 1996-03-26 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5807279A (en) * 1996-09-27 1998-09-15 Cordis Corporation Guidewire having radiopaque distal tip
US5813997A (en) * 1994-10-28 1998-09-29 Intelliwire, Inc. Guide wire with deflectable tip and method
US5882333A (en) * 1994-05-13 1999-03-16 Cardima, Inc. Catheter with deflectable distal section
US5891055A (en) * 1993-05-19 1999-04-06 Schneider (Europe) A.G. Guide wire
US5908405A (en) * 1994-10-28 1999-06-01 Intella Interventional Systems, Inc. Low profile balloon-on-a-wire catheter with shapeable and/or deflectable tip and method
US5931830A (en) * 1995-12-07 1999-08-03 Sarcos L.C. Hollow coil guide wire apparatus for catheters
US6027460A (en) * 1995-09-14 2000-02-22 Shturman Cardiology Systems, Inc. Rotatable intravascular apparatus
US6059739A (en) * 1998-05-29 2000-05-09 Medtronic, Inc. Method and apparatus for deflecting a catheter or lead
US6129649A (en) * 2000-01-18 2000-10-10 Yang; Yen-Shuo Trampoline having a jumping bed with elastic straps for supporting the same on trampoline frame
US6146338A (en) * 1999-04-23 2000-11-14 Medtronic, Inc. Apparatus for deflecting a catheter or lead
US6193706B1 (en) * 1994-03-31 2001-02-27 Lake Region Manufacturing Co., Inc. Guidewire extension system with tactile connection indication
US6273876B1 (en) * 1997-12-05 2001-08-14 Intratherapeutics, Inc. Catheter segments having circumferential supports with axial projection
US6306105B1 (en) * 1998-05-14 2001-10-23 Scimed Life Systems, Inc. High performance coil wire
US6352515B1 (en) * 1999-12-13 2002-03-05 Advanced Cardiovascular Systems, Inc. NiTi alloyed guidewires
US6355016B1 (en) * 1997-03-06 2002-03-12 Medtronic Percusurge, Inc. Catheter core wire
US6375628B1 (en) * 1997-03-06 2002-04-23 Medtronic Percusurge, Inc. Hollow medical wires and methods of constructing same
US6379369B1 (en) * 1990-12-18 2002-04-30 Advanced Cardiovascular Systems, Inc. Intracorporeal device with NiTi tubular member
US20020151966A1 (en) * 2001-03-28 2002-10-17 Eder Joseph C. Expandable coil stent
US6468230B2 (en) * 1998-02-19 2002-10-22 Medtronic Percusurge, Inc. Core wire with shapeable tip
US20020165534A1 (en) * 2001-05-02 2002-11-07 Hayzelden Robert C. Steerable catheter with torque transfer system
US6488637B1 (en) * 1996-04-30 2002-12-03 Target Therapeutics, Inc. Composite endovascular guidewire

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003369A (en) * 1975-04-22 1977-01-18 Medrad, Inc. Angiographic guidewire with safety core wire
US4183434A (en) * 1977-09-02 1980-01-15 Pharmachem Corporation Peelable seal
US4827841A (en) * 1985-04-01 1989-05-09 Consolidated Engineering And Manufacturing Corp. Ticket issuing machine
US4763647A (en) 1987-01-06 1988-08-16 C. R. Bard, Inc. Dual coil steerable guidewire
US5116350B1 (en) * 1987-03-17 1997-06-17 Cordis Corp Catheter system having distal tip for opening obstructions
US5143085A (en) * 1987-05-13 1992-09-01 Wilson Bruce C Steerable memory alloy guide wires
US5159937A (en) * 1987-09-30 1992-11-03 Advanced Cardiovascular Systems, Inc. Steerable dilatation catheter
MY103860A (en) * 1988-06-13 1993-09-30 Bard Inc C R Guidewire extension with self-latching detachable connector
US4935068A (en) * 1989-01-23 1990-06-19 Raychem Corporation Method of treating a sample of an alloy
US5069226A (en) * 1989-04-28 1991-12-03 Tokin Corporation Catheter guidewire with pseudo elastic shape memory alloy
US5120308A (en) * 1989-05-03 1992-06-09 Progressive Angioplasty Systems, Inc. Catheter with high tactile guide wire
ATE144433T1 (en) * 1990-02-02 1996-11-15 Ep Technologies STEERING MECHANISM FOR CATHETER
US5060660A (en) * 1990-02-28 1991-10-29 C. R. Bard, Inc. Steerable extendable guidewire with adjustable tip
US5078722A (en) * 1990-08-14 1992-01-07 Cordis Corporation Method and apparatus for removing deposits from a vessel
US5125395A (en) * 1990-09-12 1992-06-30 Adair Edwin Lloyd Deflectable sheath for optical catheter
US5188621A (en) * 1991-08-26 1993-02-23 Target Therapeutics Inc. Extendable guidewire assembly
US6126649A (en) * 1999-06-10 2000-10-03 Transvascular, Inc. Steerable catheter with external guidewire as catheter tip deflector
US6544197B2 (en) * 2000-10-20 2003-04-08 Radius Medical Technologies, Inc. Composite guidewire
US6682493B2 (en) 2001-12-03 2004-01-27 Scimed Life Systems, Inc. High torque guidewire

Patent Citations (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US400369A (en) * 1889-03-26 Fence-making machine
US4770188A (en) * 1979-06-30 1988-09-13 Machida Endoscope Co., Ltd. Guide tube assembly for an endoscope
US4925445A (en) * 1983-09-16 1990-05-15 Fuji Terumo Co., Ltd. Guide wire for catheter
US4665906A (en) * 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US5242394A (en) * 1985-07-30 1993-09-07 Advanced Cardiovascular Systems, Inc. Steerable dilatation catheter
US4719924A (en) * 1986-09-09 1988-01-19 C. R. Bard, Inc. Small diameter steerable guidewire with adjustable tip
US4815478A (en) * 1987-02-17 1989-03-28 Medtronic Versaflex, Inc. Steerable guidewire with deflectable tip
US4813434A (en) * 1987-02-17 1989-03-21 Medtronic Versaflex, Inc. Steerable guidewire with deflectable tip
US4757827A (en) * 1987-02-17 1988-07-19 Versaflex Delivery Systems Inc. Steerable guidewire with deflectable tip
US4923462A (en) * 1987-03-17 1990-05-08 Cordis Corporation Catheter system having a small diameter rotatable drive member
US4936845A (en) * 1987-03-17 1990-06-26 Cordis Corporation Catheter system having distal tip for opening obstructions
US4875489A (en) * 1987-08-14 1989-10-24 Advanced Cardiovascular Systems, Inc. Extendable guidewire
US4854325A (en) * 1987-11-09 1989-08-08 Stevens Robert C Reciprocating guidewire method
US4935088A (en) * 1987-12-04 1990-06-19 Masuhiro Mitsuyama Method of making a multi-pocketed paper holder
US4827941A (en) * 1987-12-23 1989-05-09 Advanced Cardiovascular Systems, Inc. Extendable guidewire for cardiovascular procedures
US4881981A (en) * 1988-04-20 1989-11-21 Johnson Service Company Method for producing a shape memory alloy member having specific physical and mechanical properties
US4940062A (en) * 1988-05-26 1990-07-10 Advanced Cardiovascular Systems, Inc. Guiding member with deflectable tip
US4984581A (en) * 1988-10-12 1991-01-15 Flexmedics Corporation Flexible guide having two-way shape memory alloy
US4886067A (en) * 1989-01-03 1989-12-12 C. R. Bard, Inc. Steerable guidewire with soft adjustable tip
US4921482A (en) * 1989-01-09 1990-05-01 Hammerslag Julius G Steerable angioplasty device
US4998916A (en) * 1989-01-09 1991-03-12 Hammerslag Julius G Steerable medical device
US5037391A (en) * 1989-01-09 1991-08-06 Pilot Cardiovascular Systems, Inc. Steerable angioplasty device
US5480382A (en) * 1989-01-09 1996-01-02 Pilot Cardiovascular Systems, Inc. Steerable medical device
US5203772A (en) * 1989-01-09 1993-04-20 Pilot Cardiovascular Systems, Inc. Steerable medical device
US5372587A (en) * 1989-01-09 1994-12-13 Pilot Cariovascular Systems, Inc. Steerable medical device
US4966163A (en) * 1989-02-14 1990-10-30 Advanced Cardiovascular Systems, Inc. Extendable guidewire for vascular procedures
US4953553A (en) * 1989-05-11 1990-09-04 Advanced Cardiovascular Systems, Inc. Pressure monitoring guidewire with a flexible distal portion
US5365942A (en) * 1990-06-04 1994-11-22 C. R. Bard, Inc. Guidewire tip construction
US6379369B1 (en) * 1990-12-18 2002-04-30 Advanced Cardiovascular Systems, Inc. Intracorporeal device with NiTi tubular member
US5397305A (en) * 1990-12-21 1995-03-14 Advanced Cardiovascular Systems, Inc. Fixed-wire dilatation catheter with rotatable balloon assembly
US5368049A (en) * 1991-05-21 1994-11-29 C. R. Bard, Inc. Superelastic formable guidewire with malleable cladding
US5190050A (en) * 1991-11-08 1993-03-02 Electro-Catheter Corporation Tip deflectable steerable catheter
US5501694A (en) * 1992-11-13 1996-03-26 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5341818A (en) * 1992-12-22 1994-08-30 Advanced Cardiovascular Systems, Inc. Guidewire with superelastic distal portion
US5695111A (en) * 1992-12-22 1997-12-09 Advanced Cardiovascular Systems, Inc. Method of soldering TI containing alloys
US5891055A (en) * 1993-05-19 1999-04-06 Schneider (Europe) A.G. Guide wire
US6193706B1 (en) * 1994-03-31 2001-02-27 Lake Region Manufacturing Co., Inc. Guidewire extension system with tactile connection indication
US5882333A (en) * 1994-05-13 1999-03-16 Cardima, Inc. Catheter with deflectable distal section
US5908405A (en) * 1994-10-28 1999-06-01 Intella Interventional Systems, Inc. Low profile balloon-on-a-wire catheter with shapeable and/or deflectable tip and method
US5813997A (en) * 1994-10-28 1998-09-29 Intelliwire, Inc. Guide wire with deflectable tip and method
US6027460A (en) * 1995-09-14 2000-02-22 Shturman Cardiology Systems, Inc. Rotatable intravascular apparatus
US5931830A (en) * 1995-12-07 1999-08-03 Sarcos L.C. Hollow coil guide wire apparatus for catheters
US6488637B1 (en) * 1996-04-30 2002-12-03 Target Therapeutics, Inc. Composite endovascular guidewire
US5807279A (en) * 1996-09-27 1998-09-15 Cordis Corporation Guidewire having radiopaque distal tip
US6355016B1 (en) * 1997-03-06 2002-03-12 Medtronic Percusurge, Inc. Catheter core wire
US6375628B1 (en) * 1997-03-06 2002-04-23 Medtronic Percusurge, Inc. Hollow medical wires and methods of constructing same
US6273876B1 (en) * 1997-12-05 2001-08-14 Intratherapeutics, Inc. Catheter segments having circumferential supports with axial projection
US6468230B2 (en) * 1998-02-19 2002-10-22 Medtronic Percusurge, Inc. Core wire with shapeable tip
US6306105B1 (en) * 1998-05-14 2001-10-23 Scimed Life Systems, Inc. High performance coil wire
US20020019599A1 (en) * 1998-05-14 2002-02-14 Maura Rooney High performance coil wire
US6059739A (en) * 1998-05-29 2000-05-09 Medtronic, Inc. Method and apparatus for deflecting a catheter or lead
US6146338A (en) * 1999-04-23 2000-11-14 Medtronic, Inc. Apparatus for deflecting a catheter or lead
US6352515B1 (en) * 1999-12-13 2002-03-05 Advanced Cardiovascular Systems, Inc. NiTi alloyed guidewires
US6129649A (en) * 2000-01-18 2000-10-10 Yang; Yen-Shuo Trampoline having a jumping bed with elastic straps for supporting the same on trampoline frame
US20020151966A1 (en) * 2001-03-28 2002-10-17 Eder Joseph C. Expandable coil stent
US20020165534A1 (en) * 2001-05-02 2002-11-07 Hayzelden Robert C. Steerable catheter with torque transfer system

Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9254143B2 (en) 1998-02-25 2016-02-09 Revascular Therapeutics, Inc. Guidewire for crossing occlusions or stenoses having a shapeable distal end
US8496680B2 (en) 2000-04-06 2013-07-30 Revascular Therapeutics Inc. Guidewire for crossing occlusions or stenoses
US8043314B2 (en) 2000-04-06 2011-10-25 Revascular Therapeutics Inc. Guidewire for crossing occlusions or stenoses
US9113955B2 (en) 2000-04-06 2015-08-25 Revascular Therapeutics, Inc. Guidewire for crossing occlusions or stenoses
US8747332B2 (en) 2000-04-06 2014-06-10 Revascular Therapeutics Inc. Guidewire for crossing occlusions or stenoses
US8353922B2 (en) 2000-04-06 2013-01-15 Revascular Therapeutics, Inc Guidewire for crossing occlusions or stenoses
US20070213689A1 (en) * 2002-03-22 2007-09-13 Grewe David D Deflectable tip infusion guidewire
US20080255446A1 (en) * 2007-04-16 2008-10-16 General Electric Company System and method of integrating electromagnetic microsensors in guidewires
US8239003B2 (en) 2007-04-16 2012-08-07 General Electric Company System and method of integrating electromagnetic microsensors in guidewires
WO2009029430A1 (en) * 2007-08-31 2009-03-05 Revascular Therapeutics, Inc. Guidewire for crossing occlusions or stenoses having a shapeable distal end
US9002435B2 (en) 2008-06-30 2015-04-07 General Electric Company System and method for integrating electromagnetic microsensors in guidewires
US20090326368A1 (en) * 2008-06-30 2009-12-31 General Electric Company System and Method For Integrating Electromagnetic Microsensors in Guidewires
US8801691B2 (en) 2008-11-26 2014-08-12 Revascular Therapeutics, Inc. Delivery and exchange catheter for storing guidewire
US8162891B2 (en) 2008-11-26 2012-04-24 Revascular Therapeutics, Inc. Delivery and exchange catheter for storing guidewire
US10980968B2 (en) 2008-12-08 2021-04-20 Scientia Vascular, Llc Micro-cutting systems for forming cuts in products
US10232141B2 (en) 2008-12-08 2019-03-19 Scientia Vascular, Llc Micro-cutting systems for forming cuts in products
US11406791B2 (en) 2009-04-03 2022-08-09 Scientia Vascular, Inc. Micro-fabricated guidewire devices having varying diameters
US10363389B2 (en) 2009-04-03 2019-07-30 Scientia Vascular, Llc Micro-fabricated guidewire devices having varying diameters
US9950137B2 (en) 2009-04-03 2018-04-24 Scientia Vascular, Llc Micro-fabricated guidewire devices formed with hybrid materials
US11779477B2 (en) 2010-11-17 2023-10-10 Abbott Cardiovascular Systems, Inc. Radiopaque intraluminal stents
US8758269B2 (en) * 2011-01-28 2014-06-24 Asahi Intecc Co., Ltd. Guidewire
US20120197159A1 (en) * 2011-01-28 2012-08-02 Asahi Intecc Co., Ltd. Guidewire
US9724494B2 (en) * 2011-06-29 2017-08-08 Abbott Cardiovascular Systems, Inc. Guide wire device including a solderable linear elastic nickel-titanium distal end section and methods of preparation therefor
US11806488B2 (en) 2011-06-29 2023-11-07 Abbott Cardiovascular Systems, Inc. Medical device including a solderable linear elastic nickel-titanium distal end section and methods of preparation therefor
US20130006149A1 (en) * 2011-06-29 2013-01-03 Abbott Cardiovascular Systems Guide Wire Device Including a Solderable Linear Elastic Nickel-Titanium Distal End Section and Methods Of Preparation Therefor
US8986225B2 (en) 2012-08-02 2015-03-24 Covidien Lp Guidewire
US11052228B2 (en) 2016-07-18 2021-07-06 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US10953202B2 (en) 2016-07-18 2021-03-23 Scientia Vascular, Llc Guidewire devices having distally extending coils and shapeable tips
WO2018017351A1 (en) * 2016-07-18 2018-01-25 Scientia Vascular, Llc Guidewire devices having shapeable polymer tips
US11207502B2 (en) 2016-07-18 2021-12-28 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US10953203B2 (en) 2016-07-18 2021-03-23 Scientia Vascular, Llc Guidewire devices having shapeable polymer tips
US11890434B2 (en) 2016-07-18 2024-02-06 Scientia Vascular, Inc. Guidewire devices having distally extending coils and shapeable tips
US10821268B2 (en) 2016-09-14 2020-11-03 Scientia Vascular, Llc Integrated coil vascular devices
US11452541B2 (en) 2016-12-22 2022-09-27 Scientia Vascular, Inc. Intravascular device having a selectively deflectable tip
US11369351B2 (en) 2017-05-26 2022-06-28 Scientia Vascular, Inc. Micro-fabricated medical device having a non-helical cut arrangement
WO2019081962A1 (en) 2017-10-24 2019-05-02 Ecole Polytechnique Federale De Lausanne (Epfl) Steerable device and system
US11305095B2 (en) 2018-02-22 2022-04-19 Scientia Vascular, Llc Microfabricated catheter having an intermediate preferred bending section
WO2020217171A1 (en) 2019-04-24 2020-10-29 Ecole Polytechnique Federale De Lausanne (Epfl) Enhanced torque steerable guidewire

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US20030181827A1 (en) 2003-09-25
DE60307533T2 (en) 2007-05-03
EP1346747B1 (en) 2006-08-16
US7128718B2 (en) 2006-10-31
DE60307533D1 (en) 2006-09-28
EP1346747A3 (en) 2004-01-02

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