US20070021731A1 - Method of and apparatus for navigating medical devices in body lumens - Google Patents
Method of and apparatus for navigating medical devices in body lumens Download PDFInfo
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- US20070021731A1 US20070021731A1 US11/475,840 US47584006A US2007021731A1 US 20070021731 A1 US20070021731 A1 US 20070021731A1 US 47584006 A US47584006 A US 47584006A US 2007021731 A1 US2007021731 A1 US 2007021731A1
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- medical device
- distal end
- magnetic field
- end portion
- catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0127—Magnetic means; Magnetic markers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09075—Basic structures of guide wires having a core without a coil possibly combined with a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09083—Basic structures of guide wires having a coil around a core
Definitions
- This invention relates to a method of, and apparatus for, navigating medical devices in body lumens, such as in blood vessels, the trachea, the gastrointestinal tract, or the urinary tract.
- vascular catheterizations and interventional neuroradiology procedures involve the introduction of medical devices through the arteries; bronchoscopies involve the introduction of medical devices through the trachea; endoscopies and colonoscopies involve the introduction of instruments through the gastrointestinal tract; and urethroscopies involve the introduction of medical devices through the urinary tract.
- the methods and apparatuses of the present invention involve magnetically guiding a medical device through a lumen in the body.
- a magnet is provided on the end of a guide wire and an externally applied magnetic field orients the magnet in the body lumen.
- the magnet can be advanced through the body lumen by manipulating the magnetic field or by pushing the guide wire.
- a catheter may be disposed over a guide wire having a magnet on its distal end.
- the guide wire and catheter combination is introduced into a body lumen through a natural or surgically formed opening. Once in the body the guide wire and catheter combination is navigated through the body lumen by applying a magnetic field, which acts on the distal end of the guide wire, orienting it.
- the guide wire is advanced slightly ahead of the catheter at a branch in the body lumen, and a magnetic field is applied to orient the tip of the guide wire, and the guide wire is advanced in the direction of the tip which is oriented into the selected branch.
- the guide wire can be advanced by the application of the magnetic field, by pushing at the proximal end, or by both.
- the catheter is then advanced over the guide wire. This process is repeated until the distal end of the catheter is at its desired location. Once the distal end of the catheter is in the desired position, the magnet can be withdrawn through the lumen of the catheter by pulling on the tether. Treatment, such as drug therapy or embolizing agents, can then be passed through the catheter.
- a guide wire with a magnet on the tip may be docked at the distal end of the lumen inside a catheter or other medical device.
- the guide wire and catheter combination is introduced into a body lumen through a natural or surgically formed opening. Once in the body lumen, the guide wire and catheter combination is navigated through the body lumen by applying a magnetic field, which acts upon the magnet-tipped guide wire in the catheter, orienting it.
- the catheter is advanced by pushing the guide wire. Once the distal end of the catheter is in the desired location, the guide wire can be withdrawn through the lumen of the catheter by pulling on the guide wire. Treatment, such as drug therapy or embolizing agents, can then be passed through the catheter.
- the methods of the various embodiments of this invention, and the guide wire of the various embodiments of this invention facilitate quick, easy and accurate positioning of a catheter or other medical device via a body lumen. Once the catheter is properly positioned, it can be used during a diagnostic or therapeutic procedure, either directly or as a passage for other medical devices.
- FIG. 1 is a longitudinal cross-sectional view of a guide wire and catheter combination constructed according to the principles of a first embodiment this invention
- FIG. 2 is a plan view of the guide wire of the first embodiment
- FIG. 3 is an enlarged cross-sectional view of the distal tip of the guide wire
- FIG. 4 is an enlarged cross sectional view the distal end of a first alternate construction of the guide wire of the first embodiment, using a socket to secure the magnet;
- FIG. 5 is an enlarged cross sectional view of the distal end of a second alternate construction of the guide wire of the first embodiment, using a collar to secure the magnet.
- FIG. 6 is an enlarged cross-sectional view of a third alternate construction of the distal section of the guide wire
- FIG. 7 is an enlarged cross-sectional view of a fourth alternate construction of the distal section of the guide wire
- FIG. 8 is a side elevation view of the distal section of a fifth alternate construction of the guide wire of the first embodiment with a portion broken away to show details of the construction;
- FIG. 9 is a side elevation view of the distal end section of a sixth alternate construction of the guide wire of the first embodiment.
- FIG. 10 is a side elevation view of the distal end section of a seventh alternate construction of the guide wire of the first embodiment
- FIG. 11 is a side elevation view of the distal section of an eighth alternate construction of the guide wire of the first embodiment
- FIG. 11 a is an enlarged side elevation view of the eighth alternate construction of the distal end section, with a portion broken away to show details of the construction;
- FIG. 12 is a side elevation view of the distal section of a ninth alternate construction of the guide wire of the first embodiment
- FIG. 12 a is a side elevation view of the distal section of the third alternate construction of the guide wire, in a magnetic field;
- FIG. 13 is a side elevation view of a tenth alternate construction of the distal section of the guide wire
- FIG. 13 a is a side elevation view of a tenth alternate construction of the distal tip of the guide wire, in a magnetic field;
- FIG. 14 is a longitudinal cross-sectional view of the guide wire and endoscope combination constructed according to the principles of the first embodiment of this invention.
- FIG. 15 is a longitudinal cross-sectional view of a guide wire and catheter combination according a second embodiment of this invention.
- FIG. 16 is a longitudinal cross-sectional view of a guide wire and catheter combination with the guide wire partially withdrawn from the lumen of the catheter;
- FIG. 17 is a side elevation view of a guide wire and biopsy device according to the principles of the present invention.
- a guide wire and magnet combination constructed according to the principles of a first embodiment of this invention is indicated generally as 20 in FIG. 1 .
- the guide wire and catheter combination 20 comprises a guide wire 22 and a catheter 24 .
- the guide wire 22 comprises a wire 26 , which is preferably made of nitinol, which is highly flexible and resists kinking, although the guide wire could be made of some other suitable material.
- a magnet 28 is mounted on the distal end 30 of the wire 26 . This magnet may either be a permanent magnet or a permeable magnetic material. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field.
- the magnet 28 is made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the guide wire 22 in the body lumen and to be retracted through the catheter 24 .
- the magnet 28 is preferably elongate so that it can orient the tip of the guide wire 22 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire.
- the magnet 28 is preferably a cylindrical body 34 with an axial bore 36 therethrough.
- the distal end of the wire 26 extends through the bore 36 , and is secured with a bead 38 of adhesive on the distal side of the magnet 28 .
- the bead 38 also provides a rounded head on the distal end 30 of the guide wire 22 .
- a first alternate construction of the guide wire 22 of the first embodiment is indicated generally as 40 in FIG. 4 .
- the guide wire 40 is similar in construction to guide wire 22 , comprising wire 42 , having a proximal end (not shown) and a distal end 44 .
- a mounting body 46 having a socket 48 therein, is attached to the distal end 44 of the wire.
- a magnet 50 is mounted in the mounting body. The magnet can be secured in the mounting body with adhesive, or the socket 48 can be crimped to secure the proximal end of the magnet 50 in the socket 48 .
- a second alternate construction of the guide wire 22 of the first embodiment is indicated generally as 60 in FIG. 5 .
- the guide wire 60 is similar in construction to guide 22 , comprising a wire 62 having a proximal end (not shown) and a distal end 64 .
- a mounting collar 66 is attached to the distal end 64 of the wire 62 .
- a magnet 68 is mounted on the mounting collar 66 .
- the magnet 68 can be secured to the mounting collar 66 by adhesive or by fusion.
- a third alternate construction of the guide wire 22 is indicated generally as 70 in FIG. 6 .
- the guide wire 70 is similar in construction to guide 22 , comprising a wire 72 having a proximal end (not shown) and a distal end 74 , and a magnet 76 mounted on the distal end of the wire 72 .
- the magnet 76 is preferably a cylindrical body with an axial bore 78 therethrough.
- the distal end of the wire 24 extends through the bore 78 , and is secured with a bead 80 of adhesive on the distal side of the magnet 76 .
- the bead 80 also provides a rounded head on the distal end of the guide wire 22 .
- the collar 82 facilitates withdrawing the magnet 76 through the distal end of the catheter 24 .
- the collar can be made of a platinum or some other non-magnetic radio opaque material so that the position of the end of the guide wire can be easily located with x-ray or fluoroscopic imaging equipment.
- a fourth alternative construction of a guide wire 22 is indicated generally as 90 in FIG. 7 .
- the guide wire 90 is similar in construction to guide wire 22 , comprising a wire 92 having a proximal end (not shown) and a distal end 94 , and a magnet 96 on the distal end of the wire 92 .
- the magnet 96 is preferably a cylindrical body with an axial bore 98 therethrough.
- the distal end of the wire 24 extends through the bore 98 , and is secured with a bead 100 of adhesive on the distal side of the magnet 96 .
- the bead 100 also provides a rounded head on the distal end of the guide wire 90 .
- the guide wire 90 includes a sheath 102 , made of flexible polyurethane tubing, extending over the wire 92 .
- the sheath 102 preferably has the same outside diameter as the magnet 96 , to smoothly slide in the lumen of the catheter, and to help prevent excessive movement of the guide wire 90 within the lumen.
- the sheath 102 is preferably secured to the proximal end of the magnet 96 with an adhesive, such as SICOMET 40 available from Tracon.
- Guide wire 110 comprises a wire 112 having a proximal end (not shown) and a distal end 114 .
- the wire 112 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material.
- a magnet 116 which can either be a permeable magnet or a permanent magnet, is secured on the distal end 114 .
- a permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field.
- the magnet 116 is preferably made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the distal tip of the guide wire 110 in the body lumen and to be retracted through the lumen of the catheter or other medical device.
- the magnet 116 is preferably elongate so that it can orient the distal tip of the guide wire 110 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire.
- the magnet 116 is preferably a cylindrical body.
- a magnetic or non-magnetic sleeve 118 made of a suitable sheet material or wire, covers the magnet 76 and extends over the distal end 114 of the guide wire 110 , securing the magnet on the wire.
- the sleeve 118 is made from a thin plastic tube, which is can be secured over the magnet and the distal end of the guide wire, with an adhesive, or more preferably, by heat shrinking.
- Guide wire 120 comprises a wire 122 having a proximal end (not shown) and a distal end 124 .
- the wire 122 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material.
- a magnet 126 which can either be a permeable magnet or a permanent magnet, is secured on the distal end 124 , for example with adhesive.
- a permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field.
- the magnet 126 is preferably made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the distal tip guide wire 120 in the body lumen and to be retracted through the lumen of the catheter or other medical device.
- the magnet 126 is preferably elongate so that it can orient the distal tip of the guide wire 120 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire.
- the magnet 126 is preferably a cylindrical body.
- a sleeve 128 made of wire, covers the magnet 126 and extends over the distal end 124 of the wire 122 , helping to secure the magnet on the wire.
- the sleeve 128 is a coil of platinum wire, the proximal end of which is secured to the wire 122 proximal to the distal end 124 , and the distal end of which is secured to the magnet 126 .
- the coil improves the axial stiffness of the distal end while leaving the guide wire flexible in other directions to permit magnetic navigation.
- the coil also improves the radiopacity of the end of the guide wire so that it can be seen on x-ray and fluoroscopic images.
- the coil is secured to the wire 122 and to the magnet 126 with adhesive.
- the adhesive preferably fills the spaces between the turns of the coil around the magnet 126 , so that the surface is smooth.
- Guide wire 130 comprises a wire 132 having a proximal end (not shown) and a distal end 134 .
- the wire 132 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material.
- a magnet 136 which can either be a permeable magnet or a permanent magnet, is secured on the distal end 132 , for example with adhesive.
- a permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field.
- the magnet 136 is preferably made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the distal tip guide wire 130 in the body lumen and to be retracted through the lumen of the catheter or other medical device.
- the magnet 136 is preferably elongate so that it can orient the distal tip of the guide wire 130 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire.
- the magnet 136 is preferably a cylindrical body.
- a coil 138 of platinum wire is disposed over the distal end portion of the wire 132 .
- the proximal end of the coil is attached to the wire 132 proximal to the distal end, and the distal end of the coil is attached to the proximal end of the magnet 136 .
- the coil improves the axial stiffness of the distal end while leaving the guide wire flexible in other directions to permit magnetic navigation.
- the coil also improves the radiopacity of the end of the guide wire so that it can be seen on x-ray and fluoroscopic images.
- the coil 98 is secured to the wire 92 and to the magnet 96 with adhesive.
- a sleeve covers the magnet 136 and extends over the coil 138 an the distal end 134 of the wire 130 , helping to secure the magnet and the coil on the wire.
- the sleeve 140 is a tube of a flexible plastic material, that is secured with an adhesive, or more preferably by heat shrinking.
- Guide wire 150 comprises a wire 152 , having a proximal end (not shown) and a distal end 154 .
- the wire 152 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material.
- the wire 152 tapers toward the distal end 154 .
- the portion of the wire 152 adjacent the distal end is surrounded by a magnetic coil 156 .
- Guide wire 160 comprises a wire 162 having a proximal end (not shown) and a distal end 164 .
- guide wire 160 has a series of spaced magnets 166 on the distal end portion 168 of the wire 162 .
- the magnets 166 each preferably have a generally cylindrical body, with an axial bore 170 extending therethrough.
- the distal portion 54 of the wire 56 extends through the bores 60 , and the magnets 52 are secured to the wire 56 in spaced apart relation with adhesive.
- the magnets 166 are preferably made from NdFeB, and have a diameter of 2 mm (0.08 inches) and are 4 mm (0.16 inches) long.
- the magnets 166 are preferably spaced over the distal 5 cm (2 inches) of the guide wire 160 , and are spaced 1 cm (0.4 inches) on center. Of course some other size magnets and/or different magnet spacing could be used. Moreover the spacing of the magnets does not have to be equal.
- This third alternate construction is particularly useful for an electrophysiology catheter where the magnetic fields could pull or shape the guide wire 160 to the heart wall, thereby guiding the electrophysiology catheter over the guide wire against the heart wall.
- the magnets 166 on the distal end portion 164 of the guide wire 160 cause the guide wire to assume a particular shape dictated by the field.
- the shape of the distal portion of the guide wire can be controlled, facilitating the navigation through, or shaping to, the body lumen.
- the guide wire 160 can be advanced by pulling with a magnetic force on the magnets 166 , or the proximal end can be manually pushed. A magnetic pulling force could also be used to hold the catheter with guide wire to the wall of a body lumen.
- a tenth alternate construction of the first embodiment of a guide wire constructed according to the principles of the present invention is indicated generally as 180 in FIGS. 13 and 13 a .
- the guide wire 180 comprises a wire 182 , having a proximal end (not shown) and a distal end 184 .
- the distal end portion 186 of guide wire 180 is made from a magnetic material.
- the distal end portion 186 is preferably about 0.25 mm (0.01 inches) in diameter, and about 1 cm (0.4 inches) long.
- the distal end portion can be made of a permeable magnetic material such as a steel or a magnetic stainless steel wire, or a steel or a magnetic stainless steel braid.
- the distal end portion 186 of the guide wire 180 assumes a particular orientation dictated by the field.
- the guide wire 180 can be advanced by magnet force on the distal end portion 186 , or the proximal end can be pushed.
- the magnetic field can also function to selectively stiffen the distal end portion 186 of the guide wire, to facilitate navigation through the body lumen. This allows the guide wire 182 to be designed with the minimum amount of stiffness to overcome static friction when applying an axial pushing force on at the proximal end. Sufficient stiffness for navigation can be provided by applying a magnetic field to the distal tip.
- the catheter 24 is preferably of conventional construction, having a proximal end 100 , a distal end 202 , and a lumen 204 extending therebetween.
- the catheter 24 can be made of polyurethane tubing, or some other suitable material.
- the size of the catheter 24 depends upon where in the body it will be introduced, and how it will be used. For example, for use in the blood vessels in the brain, the catheter might have an outside diameter of about 0.7 mm (0.03 inches), an inside diameter of about 0.6 mm (0.02 inches), and a length of about 2 m (6.6 feet).
- medical devices other than catheters can be used with the guide wire, for example an endoscope where the guide wire is inserted through its working channel.
- These devices would typically include a lumen extending all or partly along the length of the device that passes over the guide wire so that the device follows the guide wire.
- One of the guide wires of the present invention can be introduced into a body lumen, such as a blood vessel, and navigated to its desired location by the controlled application of magnetic fields.
- the application of a magnetic field allows the operator to steer the distal end of the guide wire by orienting the distal end of the guide wire to the desired direction of travel.
- the guide wire can be advanced using the magnetic field to pull the magnet on the distal end of the guide wire, or the guide wire can be advanced by pushing the proximal end.
- the catheter 24 or other medical device can be advanced over the guide wire, until the catheter or medical device is in its desired location.
- the guide wire can be left in place, or if the magnet is sufficiently small, the guide wire can be withdrawn through the lumen 204 of the catheter and out the proximal end 200 .
- the magnetic articulation of the distal end of the guide wire eliminates the need to provide a permanent bend in the guide wire in order to navigate through branches in body lumens.
- the straight configuration of the guide wires permitted by the present invention permits faster and easier navigation in straight sections of the body lumen and reduces unintentional diversion down branches of the lumen.
- one of the guide wires of this invention can be used to navigate an endoscope 300 through a body lumen, such as a colon.
- the endoscope 300 has a lumen 302 extending therethrough.
- a magnetic field is applied to orient the magnet on the distal end of the guide wire with the magnetic field.
- the endoscope 300 can then be advanced over the guide wire, the lumen 302 sliding over the guide wire.
- the guide wire is preferably incrementally advanced, and the endoscope is then advanced over the guide wire, until the distal end of the endoscope 300 reaches its desired location.
- a guide wire and catheter combination constructed according to a second embodiment of this invention is indicated generally as 400 in FIGS. 15 and 16 .
- the guide wire and catheter combination 400 comprises guide wire 402 and catheter 404 .
- the guide wire 402 comprises a wire 406 , preferably made of nitinol, which is highly flexible and resists kinking, although the guide wire could be made of some other suitable material.
- a magnet 408 is mounted on the distal end 410 of the wire 406 . This magnet may either be a permanent magnet or a permeable magnetic material. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field.
- the magnet 408 is made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to move the guide wire 402 through the body lumen.
- the magnet 408 is preferably elongate so that it can orient the tip of the guide wire 402 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire.
- the magnet is preferably a cylindrical body with an axial bore 412 therethrough.
- the distal end of the wire 410 extends through the bore 412 , and is secured with a bead 414 of adhesive on the distal side of the magnet 408 .
- the bead 414 also provides a rounded head on the distal end of the guide wire 402 .
- the guide wire 402 could have a plurality of spaced magnets on the distal end portion similar to guide wire 160 , described above, or the distal end portion of the guide wire could be made of a flexible magnetic material similar to guide wire 180 .
- the catheter 404 is preferably of conventional construction, having a proximal end 416 , a distal end 418 , and a lumen 420 extending therebetween.
- the catheter 404 can be made of polyurethane tubing, or some other suitable material.
- the size of the catheter 404 depends upon where in the body it will be introduced, and how it will be used. For example, for use in the blood vessels in the brain, the catheter might have an outside diameter of about 0.7 mm (0.13 inches), an inside diameter of about 0.6 mm (0.11 inches), and a length of about 2 m (6.5 feet).
- the guide wire 402 is adapted to fit inside the lumen 420 , and “dock” with the catheter 404 .
- the distal end of the lumen 420 has a restriction or stricture 422 for engaging the distal end of the guide wire 422 .
- This restriction or stricture is preferably formed by a annular flange 924 on ring 426 provided on the distal end of the catheter, although it could be some other reduction in the lumen that can be engaged by the guide wire.
- the ring 426 can be made of tantalum.
- the guide wire and catheter combination 400 can be introduced into a body lumen, such as a blood vessel, and navigated to its desired position by the controlled application of magnetic fields.
- the application of a magnetic field allows the operator to steer the distal end of the guide wire 402 by orienting the distal end of the guide wire to the desired direction of travel.
- the guide wire 402 can be advanced using the magnetic field to pull the magnets on the distal end or the guide wire can be advanced by pushing the proximal end. As the guide wire 402 advances, the catheter 404 can be advanced.
- the guide wire 402 can be withdrawn through the lumen 420 , and out the proximal end 416 .
- the guide wire 412 can be used to navigate a biopsy tool 428 through a body lumen such as a kidney.
- the biopsy tool 428 has a lumen 430 therein.
- the distal end of the guide wire 402 is adapted to fit into the lumen 430 and “dock” with the biopsy tool.
- a magnetic field is applied to orient the magnet 408 inside the lumen 430 of the biopsy tool 428 .
- the biopsy tool 428 can then be advanced, in the desired direction either by pushing the proximal end of the guide wire 402 , or pulling the distal end of the guide wire with the magnetic field.
- the guide wire 402 can be withdrawn.
- the guide wires of either embodiment can be used to deliver catheter or other medical devices to locations within the body accessible via a body lumen.
- the guide wire could be used to navigate a device for retrieval of man made objects stents, or body made objects e.g. stones.
- body made objects e.g. stones.
- the high degree of articulation of the tip provides the control needed to capture and recover such objects.
- one of the guide wires 22 , 40 , 50 , 60 , 70 , 90 , 110 , 120 , 130 , 150 , 160 , or 180 of the first embodiment and an associated catheter or other medical device is introduced through a natural or surgically formed opening in a body lumen.
- a magnetic field is applied to orient the distal tip within the body lumen.
- the magnetic field can also be used to advance the distal tip of the guide wire, or the guide wire can be pushed to advance the guide wire in the body lumen.
- the catheter can be advanced over the guide wire. Once the distal end of the catheter is in its desired position, the magnet is removed from the catheter by pulling the guide wire to withdraw the magnet through the lumen of the catheter.
- multiple catheters can be directed in the same general area to facilitate a medical procedure with independent control of the catheters.
- the guide wire 402 is inserted into the lumen of the catheter 404 (or other medical device) and the guide wire and catheter combination 400 of the second embodiment is introduced through an opening in a natural or surgically formed opening in a body lumen.
- a magnetic field is applied to orient the magnet 408 on the proximal end of the guide wire 402 , inside the catheter 404 .
- the guide wire and catheter are then advanced, either by applying a magnetic field, or by pushing the distal end of the guide wire.
- the guide wire 402 is removed from the catheter 404 by pulling the guide wire 402 to withdraw it from the lumen 420 of the catheter.
- the catheter 24 or 404 can be used for the administration of drug therapy or to perform a medical procedure or it can be used as a guide to insert medical devices to the area surrounding the distal end of the catheter to perform a medical procedure.
- the magnet on the guide wire can be removed from the treatment site, multiple catheters can be directed in the same general area to facilitate a medical procedure with independent control of the catheters.
- the magnet could be left in place within the catheter, if desired.
Abstract
Description
- This application is a continuation in part of PCT application Serial No. PCT/US98/02835 filed Feb. 17, 1998.
- This invention relates to a method of, and apparatus for, navigating medical devices in body lumens, such as in blood vessels, the trachea, the gastrointestinal tract, or the urinary tract.
- Many diagnostic and therapeutic medical procedures require navigating a medical device to a particular location through lumens in the body. For example, procedures such as cardiac catheterizations and interventional neuroradiology procedures involve the introduction of medical devices through the arteries; bronchoscopies involve the introduction of medical devices through the trachea; endoscopies and colonoscopies involve the introduction of instruments through the gastrointestinal tract; and urethroscopies involve the introduction of medical devices through the urinary tract.
- Numerous methods and apparatus have been developed for introducing medical devices in the body. Many of these methods employ guide wires for remotely controlling the orientation of the tip of the medical device as it is advanced in the body lumen. These guide wires typically have a bend in their distal ends, the tip is rotated until the tip is properly oriented, and the wire is then advanced. It is a difficult and tedious process to steer a medical device remotely with a guide wire since the orientation of the guide wire is difficult to control. Thus, these procedures can be prolonged, which increases the risk to the patient and fatigues the physician.
- It has been proposed to guide medical devices in the body with magnets, see Yodh, Pierce, Weggel, and Montgomery, A New Magnetic System, for ‘Intravascular Navigation’, Medical & Biological Engineering, Vol. 6, No. 2, pp. 143-147 (March 1968), incorporated herein by reference. This article proposes a magnetically tipped catheter that is steered within the body by an externally applied magnetic field. However, the magnet in this proposed device is attached to the catheter which can impair the ability to control the magnet. Moreover, there is no provision for removing the magnet and leaving the catheter or other medical device in place. Thus, only one such catheter can be directed to a given position because the magnetic field acting on one magnet will also act on the other magnets in the vicinity.
- The methods and apparatuses of the present invention involve magnetically guiding a medical device through a lumen in the body. Generally, according to the method of this invention, a magnet is provided on the end of a guide wire and an externally applied magnetic field orients the magnet in the body lumen. The magnet can be advanced through the body lumen by manipulating the magnetic field or by pushing the guide wire.
- According to a first embodiment of this invention, a catheter may be disposed over a guide wire having a magnet on its distal end. The guide wire and catheter combination is introduced into a body lumen through a natural or surgically formed opening. Once in the body the guide wire and catheter combination is navigated through the body lumen by applying a magnetic field, which acts on the distal end of the guide wire, orienting it. Typically, the guide wire is advanced slightly ahead of the catheter at a branch in the body lumen, and a magnetic field is applied to orient the tip of the guide wire, and the guide wire is advanced in the direction of the tip which is oriented into the selected branch. The guide wire can be advanced by the application of the magnetic field, by pushing at the proximal end, or by both. The catheter is then advanced over the guide wire. This process is repeated until the distal end of the catheter is at its desired location. Once the distal end of the catheter is in the desired position, the magnet can be withdrawn through the lumen of the catheter by pulling on the tether. Treatment, such as drug therapy or embolizing agents, can then be passed through the catheter.
- According to a second embodiment of this invention, a guide wire with a magnet on the tip may be docked at the distal end of the lumen inside a catheter or other medical device. The guide wire and catheter combination is introduced into a body lumen through a natural or surgically formed opening. Once in the body lumen, the guide wire and catheter combination is navigated through the body lumen by applying a magnetic field, which acts upon the magnet-tipped guide wire in the catheter, orienting it. The catheter is advanced by pushing the guide wire. Once the distal end of the catheter is in the desired location, the guide wire can be withdrawn through the lumen of the catheter by pulling on the guide wire. Treatment, such as drug therapy or embolizing agents, can then be passed through the catheter.
- The methods of the various embodiments of this invention, and the guide wire of the various embodiments of this invention, facilitate quick, easy and accurate positioning of a catheter or other medical device via a body lumen. Once the catheter is properly positioned, it can be used during a diagnostic or therapeutic procedure, either directly or as a passage for other medical devices.
- These and other features and advantages will be in part apparent and in part pointed out hereinafter.
-
FIG. 1 is a longitudinal cross-sectional view of a guide wire and catheter combination constructed according to the principles of a first embodiment this invention; -
FIG. 2 is a plan view of the guide wire of the first embodiment; -
FIG. 3 is an enlarged cross-sectional view of the distal tip of the guide wire; -
FIG. 4 is an enlarged cross sectional view the distal end of a first alternate construction of the guide wire of the first embodiment, using a socket to secure the magnet; -
FIG. 5 is an enlarged cross sectional view of the distal end of a second alternate construction of the guide wire of the first embodiment, using a collar to secure the magnet. -
FIG. 6 is an enlarged cross-sectional view of a third alternate construction of the distal section of the guide wire; -
FIG. 7 is an enlarged cross-sectional view of a fourth alternate construction of the distal section of the guide wire; -
FIG. 8 is a side elevation view of the distal section of a fifth alternate construction of the guide wire of the first embodiment with a portion broken away to show details of the construction; -
FIG. 9 is a side elevation view of the distal end section of a sixth alternate construction of the guide wire of the first embodiment; -
FIG. 10 is a side elevation view of the distal end section of a seventh alternate construction of the guide wire of the first embodiment; -
FIG. 11 is a side elevation view of the distal section of an eighth alternate construction of the guide wire of the first embodiment; -
FIG. 11 a is an enlarged side elevation view of the eighth alternate construction of the distal end section, with a portion broken away to show details of the construction; -
FIG. 12 is a side elevation view of the distal section of a ninth alternate construction of the guide wire of the first embodiment; -
FIG. 12 a is a side elevation view of the distal section of the third alternate construction of the guide wire, in a magnetic field; -
FIG. 13 is a side elevation view of a tenth alternate construction of the distal section of the guide wire; -
FIG. 13 a is a side elevation view of a tenth alternate construction of the distal tip of the guide wire, in a magnetic field; -
FIG. 14 is a longitudinal cross-sectional view of the guide wire and endoscope combination constructed according to the principles of the first embodiment of this invention; -
FIG. 15 is a longitudinal cross-sectional view of a guide wire and catheter combination according a second embodiment of this invention; -
FIG. 16 is a longitudinal cross-sectional view of a guide wire and catheter combination with the guide wire partially withdrawn from the lumen of the catheter; and -
FIG. 17 is a side elevation view of a guide wire and biopsy device according to the principles of the present invention. - Corresponding reference numbers indicate corresponding parts throughout the several views of the drawings.
- A guide wire and magnet combination constructed according to the principles of a first embodiment of this invention is indicated generally as 20 in
FIG. 1 . The guide wire andcatheter combination 20 comprises aguide wire 22 and acatheter 24. Theguide wire 22 comprises awire 26, which is preferably made of nitinol, which is highly flexible and resists kinking, although the guide wire could be made of some other suitable material. Amagnet 28 is mounted on thedistal end 30 of thewire 26. This magnet may either be a permanent magnet or a permeable magnetic material. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field. - In the preferred embodiment, the
magnet 28 is made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient theguide wire 22 in the body lumen and to be retracted through thecatheter 24. Themagnet 28 is preferably elongate so that it can orient the tip of theguide wire 22 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire. - As shown in
FIGS. 2 and 3 , themagnet 28 is preferably acylindrical body 34 with anaxial bore 36 therethrough. The distal end of thewire 26 extends through thebore 36, and is secured with abead 38 of adhesive on the distal side of themagnet 28. Thebead 38 also provides a rounded head on thedistal end 30 of theguide wire 22. - A first alternate construction of the
guide wire 22 of the first embodiment is indicated generally as 40 inFIG. 4 . Theguide wire 40 is similar in construction to guidewire 22, comprisingwire 42, having a proximal end (not shown) and adistal end 44. A mountingbody 46, having asocket 48 therein, is attached to thedistal end 44 of the wire. Amagnet 50 is mounted in the mounting body. The magnet can be secured in the mounting body with adhesive, or thesocket 48 can be crimped to secure the proximal end of themagnet 50 in thesocket 48. - A second alternate construction of the
guide wire 22 of the first embodiment is indicated generally as 60 inFIG. 5 . Theguide wire 60 is similar in construction to guide 22, comprising awire 62 having a proximal end (not shown) and adistal end 64. A mountingcollar 66 is attached to thedistal end 64 of thewire 62. A magnet 68 is mounted on the mountingcollar 66. The magnet 68 can be secured to the mountingcollar 66 by adhesive or by fusion. - A third alternate construction of the
guide wire 22 is indicated generally as 70 inFIG. 6 . Theguide wire 70 is similar in construction to guide 22, comprising awire 72 having a proximal end (not shown) and adistal end 74, and amagnet 76 mounted on the distal end of thewire 72. Themagnet 76 is preferably a cylindrical body with anaxial bore 78 therethrough. The distal end of thewire 24 extends through thebore 78, and is secured with abead 80 of adhesive on the distal side of themagnet 76. Thebead 80 also provides a rounded head on the distal end of theguide wire 22. There is a taperingcollar 82 on thewire 26 proximal to themagnet 76. Thecollar 82 facilitates withdrawing themagnet 76 through the distal end of thecatheter 24. The collar can be made of a platinum or some other non-magnetic radio opaque material so that the position of the end of the guide wire can be easily located with x-ray or fluoroscopic imaging equipment. - A fourth alternative construction of a
guide wire 22 is indicated generally as 90 inFIG. 7 . Theguide wire 90 is similar in construction to guidewire 22, comprising awire 92 having a proximal end (not shown) and adistal end 94, and amagnet 96 on the distal end of thewire 92. Themagnet 96 is preferably a cylindrical body with anaxial bore 98 therethrough. The distal end of thewire 24 extends through thebore 98, and is secured with abead 100 of adhesive on the distal side of themagnet 96. Thebead 100 also provides a rounded head on the distal end of theguide wire 90. Theguide wire 90 includes asheath 102, made of flexible polyurethane tubing, extending over thewire 92. Thesheath 102 preferably has the same outside diameter as themagnet 96, to smoothly slide in the lumen of the catheter, and to help prevent excessive movement of theguide wire 90 within the lumen. Thesheath 102 is preferably secured to the proximal end of themagnet 96 with an adhesive, such as SICOMET 40 available from Tracon. - A fifth alternate construction of the guide wire of the first embodiment is indicated generally as 110 in
FIG. 8 .Guide wire 110 comprises awire 112 having a proximal end (not shown) and adistal end 114. Thewire 112 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material. Amagnet 116, which can either be a permeable magnet or a permanent magnet, is secured on thedistal end 114. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field. - The
magnet 116 is preferably made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the distal tip of theguide wire 110 in the body lumen and to be retracted through the lumen of the catheter or other medical device. Themagnet 116 is preferably elongate so that it can orient the distal tip of theguide wire 110 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire. - As shown in
FIG. 8 , themagnet 116 is preferably a cylindrical body. A magnetic or non-magnetic sleeve 118, made of a suitable sheet material or wire, covers themagnet 76 and extends over thedistal end 114 of theguide wire 110, securing the magnet on the wire. In this preferred embodiment shown inFIG. 8 the sleeve 118 is made from a thin plastic tube, which is can be secured over the magnet and the distal end of the guide wire, with an adhesive, or more preferably, by heat shrinking. - A sixth alternate construction of the guide wire of the first embodiment is indicated generally as 120 in
FIG. 9 .Guide wire 120 comprises awire 122 having a proximal end (not shown) and adistal end 124. Thewire 122 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material. Amagnet 126, which can either be a permeable magnet or a permanent magnet, is secured on thedistal end 124, for example with adhesive. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field. - The
magnet 126 is preferably made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the distaltip guide wire 120 in the body lumen and to be retracted through the lumen of the catheter or other medical device. Themagnet 126 is preferably elongate so that it can orient the distal tip of theguide wire 120 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire. - As shown in
FIG. 9 , themagnet 126 is preferably a cylindrical body. Asleeve 128, made of wire, covers themagnet 126 and extends over thedistal end 124 of thewire 122, helping to secure the magnet on the wire. In this preferred embodiment shown inFIG. 9 , thesleeve 128 is a coil of platinum wire, the proximal end of which is secured to thewire 122 proximal to thedistal end 124, and the distal end of which is secured to themagnet 126. The coil improves the axial stiffness of the distal end while leaving the guide wire flexible in other directions to permit magnetic navigation. The coil also improves the radiopacity of the end of the guide wire so that it can be seen on x-ray and fluoroscopic images. The coil is secured to thewire 122 and to themagnet 126 with adhesive. The adhesive preferably fills the spaces between the turns of the coil around themagnet 126, so that the surface is smooth. - A seventh alternate construction of the guide wire of the first embodiment is indicated generally as 130 in
FIG. 10 .Guide wire 130 comprises awire 132 having a proximal end (not shown) and adistal end 134. Thewire 132 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material. Amagnet 136, which can either be a permeable magnet or a permanent magnet, is secured on thedistal end 132, for example with adhesive. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field. - The
magnet 136 is preferably made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the distaltip guide wire 130 in the body lumen and to be retracted through the lumen of the catheter or other medical device. Themagnet 136 is preferably elongate so that it can orient the distal tip of theguide wire 130 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire. - As shown in
FIG. 10 , themagnet 136 is preferably a cylindrical body. Acoil 138 of platinum wire is disposed over the distal end portion of thewire 132. The proximal end of the coil is attached to thewire 132 proximal to the distal end, and the distal end of the coil is attached to the proximal end of themagnet 136. The coil improves the axial stiffness of the distal end while leaving the guide wire flexible in other directions to permit magnetic navigation. The coil also improves the radiopacity of the end of the guide wire so that it can be seen on x-ray and fluoroscopic images. Thecoil 98 is secured to thewire 92 and to themagnet 96 with adhesive. A sleeve covers themagnet 136 and extends over thecoil 138 an thedistal end 134 of thewire 130, helping to secure the magnet and the coil on the wire. In this preferred embodiment shown inFIG. 10 , the sleeve 140 is a tube of a flexible plastic material, that is secured with an adhesive, or more preferably by heat shrinking. - An eighth alternate construction of the guide wire of the first embodiment is indicated generally as 150 in
FIGS. 11 and 11 a.Guide wire 150 comprises awire 152, having a proximal end (not shown) and adistal end 154. Thewire 152 is preferably made of nitinol, which is highly flexible and resists kinking, although it could be made of some other suitable material. Thewire 152 tapers toward thedistal end 154. The portion of thewire 152 adjacent the distal end is surrounded by amagnetic coil 156. - A ninth alternate construction of the first embodiment of a guide wire according to the principles of this invention is indicated generally as 160 in
FIGS. 12 and 12 a.Guide wire 160 comprises awire 162 having a proximal end (not shown) and adistal end 164. Instead of a single magnet on the distal end of the wire, as in the first embodiment,guide wire 160 has a series of spacedmagnets 166 on thedistal end portion 168 of thewire 162. Themagnets 166 each preferably have a generally cylindrical body, with anaxial bore 170 extending therethrough. The distal portion 54 of the wire 56 extends through thebores 60, and the magnets 52 are secured to the wire 56 in spaced apart relation with adhesive. - The
magnets 166 are preferably made from NdFeB, and have a diameter of 2 mm (0.08 inches) and are 4 mm (0.16 inches) long. Themagnets 166 are preferably spaced over the distal 5 cm (2 inches) of theguide wire 160, and are spaced 1 cm (0.4 inches) on center. Of course some other size magnets and/or different magnet spacing could be used. Moreover the spacing of the magnets does not have to be equal. This third alternate construction is particularly useful for an electrophysiology catheter where the magnetic fields could pull or shape theguide wire 160 to the heart wall, thereby guiding the electrophysiology catheter over the guide wire against the heart wall. - As shown in
FIG. 12 a, upon the application of a magnetic field, themagnets 166 on thedistal end portion 164 of theguide wire 160 cause the guide wire to assume a particular shape dictated by the field. Thus by controlling the applied magnetic field, the shape of the distal portion of the guide wire can be controlled, facilitating the navigation through, or shaping to, the body lumen. Theguide wire 160 can be advanced by pulling with a magnetic force on themagnets 166, or the proximal end can be manually pushed. A magnetic pulling force could also be used to hold the catheter with guide wire to the wall of a body lumen. - A tenth alternate construction of the first embodiment of a guide wire constructed according to the principles of the present invention is indicated generally as 180 in
FIGS. 13 and 13 a. Theguide wire 180 comprises awire 182, having a proximal end (not shown) and adistal end 184. Instead of the single magnet on the distal end of the wire, or a plurality of magnets on the distal end portion of the wire, thedistal end portion 186 ofguide wire 180 is made from a magnetic material. - The
distal end portion 186 is preferably about 0.25 mm (0.01 inches) in diameter, and about 1 cm (0.4 inches) long. The distal end portion can be made of a permeable magnetic material such as a steel or a magnetic stainless steel wire, or a steel or a magnetic stainless steel braid. - As shown in
FIG. 13 a, upon the application of a magnetic field, thedistal end portion 186 of theguide wire 180 assumes a particular orientation dictated by the field. Thus by controlling the applied magnetic field, the orientation and/or shape of thedistal portion 186 of theguide wire 180 can be controlled, facilitating the navigation through the body lumen. Theguide wire 180 can be advanced by magnet force on thedistal end portion 186, or the proximal end can be pushed. The magnetic field can also function to selectively stiffen thedistal end portion 186 of the guide wire, to facilitate navigation through the body lumen. This allows theguide wire 182 to be designed with the minimum amount of stiffness to overcome static friction when applying an axial pushing force on at the proximal end. Sufficient stiffness for navigation can be provided by applying a magnetic field to the distal tip. - As shown in
FIG. 1 , thecatheter 24 is preferably of conventional construction, having aproximal end 100, adistal end 202, and alumen 204 extending therebetween. Thecatheter 24 can be made of polyurethane tubing, or some other suitable material. The size of thecatheter 24 depends upon where in the body it will be introduced, and how it will be used. For example, for use in the blood vessels in the brain, the catheter might have an outside diameter of about 0.7 mm (0.03 inches), an inside diameter of about 0.6 mm (0.02 inches), and a length of about 2 m (6.6 feet). Of course, medical devices other than catheters can be used with the guide wire, for example an endoscope where the guide wire is inserted through its working channel. These devices would typically include a lumen extending all or partly along the length of the device that passes over the guide wire so that the device follows the guide wire. One of the guide wires of the present invention can be introduced into a body lumen, such as a blood vessel, and navigated to its desired location by the controlled application of magnetic fields. The application of a magnetic field allows the operator to steer the distal end of the guide wire by orienting the distal end of the guide wire to the desired direction of travel. The guide wire can be advanced using the magnetic field to pull the magnet on the distal end of the guide wire, or the guide wire can be advanced by pushing the proximal end. As the guide wire advances, thecatheter 24 or other medical device can be advanced over the guide wire, until the catheter or medical device is in its desired location. - Once the
distal end 202 of thecatheter 24 has been placed in its desired location, the guide wire can be left in place, or if the magnet is sufficiently small, the guide wire can be withdrawn through thelumen 204 of the catheter and out theproximal end 200. - The magnetic articulation of the distal end of the guide wire eliminates the need to provide a permanent bend in the guide wire in order to navigate through branches in body lumens. The straight configuration of the guide wires permitted by the present invention permits faster and easier navigation in straight sections of the body lumen and reduces unintentional diversion down branches of the lumen.
- As shown in
FIG. 14 , one of the guide wires of this invention can be used to navigate anendoscope 300 through a body lumen, such as a colon. Theendoscope 300 has alumen 302 extending therethrough. A magnetic field is applied to orient the magnet on the distal end of the guide wire with the magnetic field. Theendoscope 300 can then be advanced over the guide wire, thelumen 302 sliding over the guide wire. The guide wire is preferably incrementally advanced, and the endoscope is then advanced over the guide wire, until the distal end of theendoscope 300 reaches its desired location. - A guide wire and catheter combination constructed according to a second embodiment of this invention is indicated generally as 400 in
FIGS. 15 and 16 . The guide wire andcatheter combination 400 comprisesguide wire 402 andcatheter 404. Theguide wire 402 comprises awire 406, preferably made of nitinol, which is highly flexible and resists kinking, although the guide wire could be made of some other suitable material. Amagnet 408 is mounted on thedistal end 410 of thewire 406. This magnet may either be a permanent magnet or a permeable magnetic material. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field. - In the preferred embodiment, the
magnet 408 is made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to move theguide wire 402 through the body lumen. Themagnet 408 is preferably elongate so that it can orient the tip of theguide wire 402 in the presence of an applied magnetic field. Magnets of about 0.3 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) long are sufficiently large for use in navigating a guide wire. - As shown in
FIG. 16 , the magnet is preferably a cylindrical body with anaxial bore 412 therethrough. The distal end of thewire 410 extends through thebore 412, and is secured with abead 414 of adhesive on the distal side of themagnet 408. Thebead 414 also provides a rounded head on the distal end of theguide wire 402. Of course instead ofmagnet 408, theguide wire 402 could have a plurality of spaced magnets on the distal end portion similar to guidewire 160, described above, or the distal end portion of the guide wire could be made of a flexible magnetic material similar to guidewire 180. - The
catheter 404 is preferably of conventional construction, having aproximal end 416, adistal end 418, and alumen 420 extending therebetween. Thecatheter 404 can be made of polyurethane tubing, or some other suitable material. The size of thecatheter 404 depends upon where in the body it will be introduced, and how it will be used. For example, for use in the blood vessels in the brain, the catheter might have an outside diameter of about 0.7 mm (0.13 inches), an inside diameter of about 0.6 mm (0.11 inches), and a length of about 2 m (6.5 feet). - The
guide wire 402 is adapted to fit inside thelumen 420, and “dock” with thecatheter 404. To facilitate this, the distal end of thelumen 420 has a restriction orstricture 422 for engaging the distal end of theguide wire 422. This restriction or stricture is preferably formed by a annular flange 924 on ring 426 provided on the distal end of the catheter, although it could be some other reduction in the lumen that can be engaged by the guide wire. The ring 426 can be made of tantalum. - The guide wire and
catheter combination 400 can be introduced into a body lumen, such as a blood vessel, and navigated to its desired position by the controlled application of magnetic fields. The application of a magnetic field allows the operator to steer the distal end of theguide wire 402 by orienting the distal end of the guide wire to the desired direction of travel. Theguide wire 402 can be advanced using the magnetic field to pull the magnets on the distal end or the guide wire can be advanced by pushing the proximal end. As theguide wire 402 advances, thecatheter 404 can be advanced. - Once the
distal end 418 of thecatheter 404 has been placed in its desired location, theguide wire 402 can be withdrawn through thelumen 420, and out theproximal end 416. - As shown in
FIG. 17 , theguide wire 412 can be used to navigate abiopsy tool 428 through a body lumen such as a kidney. Thebiopsy tool 428 has alumen 430 therein. The distal end of theguide wire 402 is adapted to fit into thelumen 430 and “dock” with the biopsy tool. A magnetic field is applied to orient themagnet 408 inside thelumen 430 of thebiopsy tool 428. Thebiopsy tool 428 can then be advanced, in the desired direction either by pushing the proximal end of theguide wire 402, or pulling the distal end of the guide wire with the magnetic field. When thebiopsy tool 428 has been advanced to its desired location, theguide wire 402 can be withdrawn. - The guide wires of either embodiment can be used to deliver catheter or other medical devices to locations within the body accessible via a body lumen. For example the guide wire could be used to navigate a device for retrieval of man made objects stents, or body made objects e.g. stones. The high degree of articulation of the tip provides the control needed to capture and recover such objects.
- Operation
- In operation, one of the
guide wires - Because the magnet on the guide wire can be removed from the treatment site, multiple catheters can be directed in the same general area to facilitate a medical procedure with independent control of the catheters.
- In operation, the
guide wire 402 is inserted into the lumen of the catheter 404 (or other medical device) and the guide wire andcatheter combination 400 of the second embodiment is introduced through an opening in a natural or surgically formed opening in a body lumen. A magnetic field is applied to orient themagnet 408 on the proximal end of theguide wire 402, inside thecatheter 404. The guide wire and catheter are then advanced, either by applying a magnetic field, or by pushing the distal end of the guide wire. Once thedistal end 418 of the catheter is in its desired position, theguide wire 402 is removed from thecatheter 404 by pulling theguide wire 402 to withdraw it from thelumen 420 of the catheter. - Once the
catheter - Because the magnet on the guide wire can be removed from the treatment site, multiple catheters can be directed in the same general area to facilitate a medical procedure with independent control of the catheters. Of course, the magnet could be left in place within the catheter, if desired.
Claims (21)
Priority Applications (1)
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US11/475,840 US20070021731A1 (en) | 1997-11-12 | 2006-06-27 | Method of and apparatus for navigating medical devices in body lumens |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/969,165 US5931818A (en) | 1997-08-29 | 1997-11-12 | Method of and apparatus for intraparenchymal positioning of medical devices |
PCT/US1998/002835 WO1999040957A1 (en) | 1998-02-17 | 1998-02-17 | Method of and apparatus for navigating medical devices in body lumens |
US09/200,055 US7066924B1 (en) | 1997-11-12 | 1998-11-25 | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
US11/475,840 US20070021731A1 (en) | 1997-11-12 | 2006-06-27 | Method of and apparatus for navigating medical devices in body lumens |
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US08/969,165 Continuation-In-Part US5931818A (en) | 1997-08-29 | 1997-11-12 | Method of and apparatus for intraparenchymal positioning of medical devices |
PCT/US1998/002835 Continuation-In-Part WO1999040957A1 (en) | 1997-11-12 | 1998-02-17 | Method of and apparatus for navigating medical devices in body lumens |
US09/200,055 Continuation US7066924B1 (en) | 1997-11-12 | 1998-11-25 | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
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US20070021731A1 true US20070021731A1 (en) | 2007-01-25 |
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US09/200,055 Expired - Lifetime US7066924B1 (en) | 1997-11-12 | 1998-11-25 | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
US11/475,840 Abandoned US20070021731A1 (en) | 1997-11-12 | 2006-06-27 | Method of and apparatus for navigating medical devices in body lumens |
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US09/200,055 Expired - Lifetime US7066924B1 (en) | 1997-11-12 | 1998-11-25 | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
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US20070167720A1 (en) * | 2005-12-06 | 2007-07-19 | Viswanathan Raju R | Smart card control of medical devices |
US20070197899A1 (en) * | 2006-01-17 | 2007-08-23 | Ritter Rogers C | Apparatus and method for magnetic navigation using boost magnets |
US20070197906A1 (en) * | 2006-01-24 | 2007-08-23 | Ritter Rogers C | Magnetic field shape-adjustable medical device and method of using the same |
US20070250041A1 (en) * | 2006-04-19 | 2007-10-25 | Werp Peter R | Extendable Interventional Medical Devices |
US20070282382A1 (en) * | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and device for lymphatic system monitoring |
US20070282376A1 (en) * | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and apparatus for neural stimulation via the lymphatic system |
US20070282386A1 (en) * | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
US20070282380A1 (en) * | 2006-06-06 | 2007-12-06 | Cardiac Pacemakers | Cardiac stimulation and sensing with endolymphatically implanted lead |
US20070287909A1 (en) * | 1998-08-07 | 2007-12-13 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling catheters in body lumens and cavities |
US20080015670A1 (en) * | 2006-01-17 | 2008-01-17 | Carlo Pappone | Methods and devices for cardiac ablation |
US20080016677A1 (en) * | 2002-01-23 | 2008-01-24 | Stereotaxis, Inc. | Rotating and pivoting magnet for magnetic navigation |
US20080039830A1 (en) * | 2006-08-14 | 2008-02-14 | Munger Gareth T | Method and Apparatus for Ablative Recanalization of Blocked Vasculature |
US20080047568A1 (en) * | 1999-10-04 | 2008-02-28 | Ritter Rogers C | Method for Safely and Efficiently Navigating Magnetic Devices in the Body |
US20080059598A1 (en) * | 2006-09-06 | 2008-03-06 | Garibaldi Jeffrey M | Coordinated Control for Multiple Computer-Controlled Medical Systems |
US20080055239A1 (en) * | 2006-09-06 | 2008-03-06 | Garibaldi Jeffrey M | Global Input Device for Multiple Computer-Controlled Medical Systems |
US20080058609A1 (en) * | 2006-09-06 | 2008-03-06 | Stereotaxis, Inc. | Workflow driven method of performing multi-step medical procedures |
US20080064969A1 (en) * | 2006-09-11 | 2008-03-13 | Nathan Kastelein | Automated Mapping of Anatomical Features of Heart Chambers |
US20080065061A1 (en) * | 2006-09-08 | 2008-03-13 | Viswanathan Raju R | Impedance-Based Cardiac Therapy Planning Method with a Remote Surgical Navigation System |
US20080077007A1 (en) * | 2002-06-28 | 2008-03-27 | Hastings Roger N | Method of Navigating Medical Devices in the Presence of Radiopaque Material |
US20080097412A1 (en) * | 2006-09-01 | 2008-04-24 | Shuros Allan C | Method and apparatus for endolymphatic drug delivery |
US20080097200A1 (en) * | 2006-10-20 | 2008-04-24 | Blume Walter M | Location and Display of Occluded Portions of Vessels on 3-D Angiographic Images |
US20080132910A1 (en) * | 2006-11-07 | 2008-06-05 | Carlo Pappone | Control for a Remote Navigation System |
US20080195171A1 (en) * | 2007-02-13 | 2008-08-14 | Sharma Virender K | Method and Apparatus for Electrical Stimulation of the Pancreatico-Biliary System |
US20080200913A1 (en) * | 2007-02-07 | 2008-08-21 | Viswanathan Raju R | Single Catheter Navigation for Diagnosis and Treatment of Arrhythmias |
US20080208912A1 (en) * | 2007-02-26 | 2008-08-28 | Garibaldi Jeffrey M | System and method for providing contextually relevant medical information |
US20080228068A1 (en) * | 2007-03-13 | 2008-09-18 | Viswanathan Raju R | Automated Surgical Navigation with Electro-Anatomical and Pre-Operative Image Data |
US20080228065A1 (en) * | 2007-03-13 | 2008-09-18 | Viswanathan Raju R | System and Method for Registration of Localization and Imaging Systems for Navigational Control of Medical Devices |
US20080287909A1 (en) * | 2007-05-17 | 2008-11-20 | Viswanathan Raju R | Method and apparatus for intra-chamber needle injection treatment |
US20080292901A1 (en) * | 2007-05-24 | 2008-11-27 | Hon Hai Precision Industry Co., Ltd. | Magnesium alloy and thin workpiece made of the same |
US20080294232A1 (en) * | 2007-05-22 | 2008-11-27 | Viswanathan Raju R | Magnetic cell delivery |
US20080312673A1 (en) * | 2007-06-05 | 2008-12-18 | Viswanathan Raju R | Method and apparatus for CTO crossing |
US20090012821A1 (en) * | 2007-07-06 | 2009-01-08 | Guy Besson | Management of live remote medical display |
US20090062646A1 (en) * | 2005-07-07 | 2009-03-05 | Creighton Iv Francis M | Operation of a remote medical navigation system using ultrasound image |
US20090082722A1 (en) * | 2007-08-21 | 2009-03-26 | Munger Gareth T | Remote navigation advancer devices and methods of use |
US20090105579A1 (en) * | 2007-10-19 | 2009-04-23 | Garibaldi Jeffrey M | Method and apparatus for remotely controlled navigation using diagnostically enhanced intra-operative three-dimensional image data |
US20090131927A1 (en) * | 2007-11-20 | 2009-05-21 | Nathan Kastelein | Method and apparatus for remote detection of rf ablation |
US20090131798A1 (en) * | 2007-11-19 | 2009-05-21 | Minar Christopher D | Method and apparatus for intravascular imaging and occlusion crossing |
US20090177037A1 (en) * | 2007-06-27 | 2009-07-09 | Viswanathan Raju R | Remote control of medical devices using real time location data |
US20090177032A1 (en) * | 1999-04-14 | 2009-07-09 | Garibaldi Jeffrey M | Method and apparatus for magnetically controlling endoscopes in body lumens and cavities |
US20100069733A1 (en) * | 2008-09-05 | 2010-03-18 | Nathan Kastelein | Electrophysiology catheter with electrode loop |
US20100163061A1 (en) * | 2000-04-11 | 2010-07-01 | Creighton Francis M | Magnets with varying magnetization direction and method of making such magnets |
US7772950B2 (en) | 2005-08-10 | 2010-08-10 | Stereotaxis, Inc. | Method and apparatus for dynamic magnetic field control using multiple magnets |
US20100222669A1 (en) * | 2006-08-23 | 2010-09-02 | William Flickinger | Medical device guide |
US7818076B2 (en) | 2005-07-26 | 2010-10-19 | Stereotaxis, Inc. | Method and apparatus for multi-system remote surgical navigation from a single control center |
US20100298845A1 (en) * | 2009-05-25 | 2010-11-25 | Kidd Brian L | Remote manipulator device |
US20110022029A1 (en) * | 2004-12-20 | 2011-01-27 | Viswanathan Raju R | Contact over-torque with three-dimensional anatomical data |
US20110033100A1 (en) * | 2005-02-07 | 2011-02-10 | Viswanathan Raju R | Registration of three-dimensional image data to 2d-image-derived data |
US7894906B2 (en) | 2006-06-06 | 2011-02-22 | Cardiac Pacemakers, Inc. | Amelioration of chronic pain by endolymphatic stimulation |
US20110046618A1 (en) * | 2009-08-04 | 2011-02-24 | Minar Christopher D | Methods and systems for treating occluded blood vessels and other body cannula |
US20110130718A1 (en) * | 2009-05-25 | 2011-06-02 | Kidd Brian L | Remote Manipulator Device |
US7961924B2 (en) | 2006-08-21 | 2011-06-14 | Stereotaxis, Inc. | Method of three-dimensional device localization using single-plane imaging |
US7966059B2 (en) | 1999-10-04 | 2011-06-21 | Stereotaxis, Inc. | Rotating and pivoting magnet for magnetic navigation |
US8196590B2 (en) | 2003-05-02 | 2012-06-12 | Stereotaxis, Inc. | Variable magnetic moment MR navigation |
US8231618B2 (en) | 2007-11-05 | 2012-07-31 | Stereotaxis, Inc. | Magnetically guided energy delivery apparatus |
US8242972B2 (en) | 2006-09-06 | 2012-08-14 | Stereotaxis, Inc. | System state driven display for medical procedures |
US8308628B2 (en) | 2009-11-02 | 2012-11-13 | Pulse Therapeutics, Inc. | Magnetic-based systems for treating occluded vessels |
US20130046203A1 (en) * | 2011-08-18 | 2013-02-21 | Richard M. DeMello | Coaxial guidewire for small vessel access |
US20150257705A1 (en) * | 2008-08-06 | 2015-09-17 | Carag Ag | Catheter for Measuring the Blood Flow of a Body Tissue |
EP3056161A1 (en) | 2015-02-16 | 2016-08-17 | Biosense Webster (Israel) Ltd. | Angioplasty guidewire |
US9883878B2 (en) | 2012-05-15 | 2018-02-06 | Pulse Therapeutics, Inc. | Magnetic-based systems and methods for manipulation of magnetic particles |
US10252030B2 (en) | 2017-01-17 | 2019-04-09 | Cook Medical Technologies Llc | Handheld magnetic gun for guide wire manipulation |
US10349817B2 (en) * | 2017-01-12 | 2019-07-16 | Endostart S.r.l. | Method for introducing colonoscope using endoscopic guide |
US10376694B2 (en) | 2008-10-09 | 2019-08-13 | Virender K. Sharma | Method and apparatus for stimulating the vascular system |
US10603489B2 (en) | 2008-10-09 | 2020-03-31 | Virender K. Sharma | Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage |
US10722139B2 (en) | 2015-02-16 | 2020-07-28 | Biosense Webster (Israel) Ltd. | Navigation of an angioplasty guidewire |
US11278189B2 (en) | 2017-01-12 | 2022-03-22 | Endostart S.r.l. | Endoscopic guide including anchoring head that accommodates a magnetic or ferromagnetic agent |
US11918315B2 (en) | 2018-05-03 | 2024-03-05 | Pulse Therapeutics, Inc. | Determination of structure and traversal of occlusions using magnetic particles |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6703418B2 (en) * | 1991-02-26 | 2004-03-09 | Unimed Pharmaceuticals, Inc. | Appetite stimulation and induction of weight gain in patients suffering from symptomatic HIV infection |
US7066924B1 (en) * | 1997-11-12 | 2006-06-27 | Stereotaxis, Inc. | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
US6505062B1 (en) * | 1998-02-09 | 2003-01-07 | Stereotaxis, Inc. | Method for locating magnetic implant by source field |
US6401723B1 (en) * | 2000-02-16 | 2002-06-11 | Stereotaxis, Inc. | Magnetic medical devices with changeable magnetic moments and method of navigating magnetic medical devices with changeable magnetic moments |
US7766856B2 (en) * | 2001-05-06 | 2010-08-03 | Stereotaxis, Inc. | System and methods for advancing a catheter |
DE60229630D1 (en) * | 2001-05-06 | 2008-12-11 | Stereotaxis Inc | System for advancing a catheter |
US7635342B2 (en) * | 2001-05-06 | 2009-12-22 | Stereotaxis, Inc. | System and methods for medical device advancement and rotation |
DE10219594A1 (en) * | 2002-05-02 | 2003-11-13 | Philips Intellectual Property | Transcutaneous catheter guidance method |
WO2004045387A2 (en) | 2002-11-18 | 2004-06-03 | Stereotaxis, Inc. | Magnetically navigable balloon catheters |
US6980843B2 (en) | 2003-05-21 | 2005-12-27 | Stereotaxis, Inc. | Electrophysiology catheter |
US20050154259A1 (en) * | 2004-01-14 | 2005-07-14 | Demarco Thomas J. | Magnetically guided colonoscope |
WO2005087114A1 (en) * | 2004-03-10 | 2005-09-22 | Philips Intellectual Property & Standards Gmbh | Catheter, apparatus and method for therapeutic embolization |
JP4500310B2 (en) * | 2004-05-14 | 2010-07-14 | オリンパス株式会社 | Insertion device and endoscope system |
US7540866B2 (en) | 2004-06-04 | 2009-06-02 | Stereotaxis, Inc. | User interface for remote control of medical devices |
US20060036163A1 (en) * | 2004-07-19 | 2006-02-16 | Viswanathan Raju R | Method of, and apparatus for, controlling medical navigation systems |
US20060144407A1 (en) * | 2004-07-20 | 2006-07-06 | Anthony Aliberto | Magnetic navigation manipulation apparatus |
US20080006280A1 (en) * | 2004-07-20 | 2008-01-10 | Anthony Aliberto | Magnetic navigation maneuvering sheath |
US20060144408A1 (en) * | 2004-07-23 | 2006-07-06 | Ferry Steven J | Micro-catheter device and method of using same |
BRPI0515007A (en) | 2004-08-12 | 2008-07-01 | Navotek Medical Ltd | computerized system for tracking and tracing of irradiated ionization source, sensor for targeting located on an ionized radiation source, method for determining device location, method of locating device manufacturing, and use of ionizing radiation shield |
US20070299550A1 (en) * | 2004-09-28 | 2007-12-27 | Osaka University | Three-Dimensional Guidance System And Method , And Drug Delivery System |
US7831294B2 (en) * | 2004-10-07 | 2010-11-09 | Stereotaxis, Inc. | System and method of surgical imagining with anatomical overlay for navigation of surgical devices |
US20080262473A1 (en) * | 2004-10-19 | 2008-10-23 | Navotek Medical Ltd. | Locating a Catheter Tip Using a Tracked Guide |
US7742803B2 (en) * | 2005-05-06 | 2010-06-22 | Stereotaxis, Inc. | Voice controlled user interface for remote navigation systems |
US20060281990A1 (en) * | 2005-05-06 | 2006-12-14 | Viswanathan Raju R | User interfaces and navigation methods for vascular navigation |
US20070062546A1 (en) * | 2005-06-02 | 2007-03-22 | Viswanathan Raju R | Electrophysiology catheter and system for gentle and firm wall contact |
US20070021744A1 (en) * | 2005-07-07 | 2007-01-25 | Creighton Francis M Iv | Apparatus and method for performing ablation with imaging feedback |
US20070038065A1 (en) * | 2005-07-07 | 2007-02-15 | Creighton Francis M Iv | Operation of a remote medical navigation system using ultrasound image |
US7603905B2 (en) * | 2005-07-08 | 2009-10-20 | Stereotaxis, Inc. | Magnetic navigation and imaging system |
US7690619B2 (en) * | 2005-07-12 | 2010-04-06 | Stereotaxis, Inc. | Apparatus for pivotally orienting a projection device |
US7416335B2 (en) * | 2005-07-15 | 2008-08-26 | Sterotaxis, Inc. | Magnetically shielded x-ray tube |
US8192374B2 (en) * | 2005-07-18 | 2012-06-05 | Stereotaxis, Inc. | Estimation of contact force by a medical device |
US20070040670A1 (en) * | 2005-07-26 | 2007-02-22 | Viswanathan Raju R | System and network for remote medical procedures |
US20070043455A1 (en) * | 2005-07-26 | 2007-02-22 | Viswanathan Raju R | Apparatus and methods for automated sequential movement control for operation of a remote navigation system |
CN101282760A (en) * | 2005-08-11 | 2008-10-08 | 纳沃特克医药有限公司 | Medical treatment system and method using radioactivity based position sensor |
BRPI0616514A2 (en) * | 2005-08-11 | 2011-06-21 | Navotek Medical Ltd | medical treatment system and method using position sensor based radioactivity |
EP1922011B1 (en) * | 2005-08-11 | 2012-05-02 | Navotek Medical Ltd. | Localization of a radioactive source |
US8784336B2 (en) | 2005-08-24 | 2014-07-22 | C. R. Bard, Inc. | Stylet apparatuses and methods of manufacture |
US20070055124A1 (en) * | 2005-09-01 | 2007-03-08 | Viswanathan Raju R | Method and system for optimizing left-heart lead placement |
DE102006020402B3 (en) * | 2006-04-28 | 2007-11-15 | Siemens Ag | A method for delivering a catheter to a target in a patient's brain and a microcatheter guidewire for use in a patient's brain |
US20080015427A1 (en) * | 2006-06-30 | 2008-01-17 | Nathan Kastelein | System and network for remote medical procedures |
US20080051626A1 (en) * | 2006-08-28 | 2008-02-28 | Olympus Medical Systems Corp. | Fistulectomy method between first duct and second duct, ultrasonic endoscope, catheter with balloon, magnet retaining device, and magnet set |
US8388546B2 (en) | 2006-10-23 | 2013-03-05 | Bard Access Systems, Inc. | Method of locating the tip of a central venous catheter |
US7794407B2 (en) | 2006-10-23 | 2010-09-14 | Bard Access Systems, Inc. | Method of locating the tip of a central venous catheter |
US20100063384A1 (en) | 2006-11-15 | 2010-03-11 | Navotek Medical Ltd. | Local intra-body delivery system |
WO2009029869A2 (en) * | 2007-08-30 | 2009-03-05 | Syncro Medical Innovations, Inc. | Guided catheter with removable magnetic guide |
US10751509B2 (en) | 2007-11-26 | 2020-08-25 | C. R. Bard, Inc. | Iconic representations for guidance of an indwelling medical device |
US8781555B2 (en) | 2007-11-26 | 2014-07-15 | C. R. Bard, Inc. | System for placement of a catheter including a signal-generating stylet |
US8849382B2 (en) | 2007-11-26 | 2014-09-30 | C. R. Bard, Inc. | Apparatus and display methods relating to intravascular placement of a catheter |
US10524691B2 (en) * | 2007-11-26 | 2020-01-07 | C. R. Bard, Inc. | Needle assembly including an aligned magnetic element |
US9521961B2 (en) | 2007-11-26 | 2016-12-20 | C. R. Bard, Inc. | Systems and methods for guiding a medical instrument |
US8388541B2 (en) | 2007-11-26 | 2013-03-05 | C. R. Bard, Inc. | Integrated system for intravascular placement of a catheter |
US10449330B2 (en) | 2007-11-26 | 2019-10-22 | C. R. Bard, Inc. | Magnetic element-equipped needle assemblies |
US9649048B2 (en) | 2007-11-26 | 2017-05-16 | C. R. Bard, Inc. | Systems and methods for breaching a sterile field for intravascular placement of a catheter |
US8478382B2 (en) | 2008-02-11 | 2013-07-02 | C. R. Bard, Inc. | Systems and methods for positioning a catheter |
WO2009105720A2 (en) * | 2008-02-20 | 2009-08-27 | Guided Delivery Systems, Inc. | Electrophysiology catheter system |
EP2156806A1 (en) * | 2008-08-18 | 2010-02-24 | Navotek Medical Ltd. | Implantation device for soft tissue markers and other implants |
US9901714B2 (en) | 2008-08-22 | 2018-02-27 | C. R. Bard, Inc. | Catheter assembly including ECG sensor and magnetic assemblies |
EP2331182A1 (en) * | 2008-09-02 | 2011-06-15 | Syncro Medical Innovations, Inc. | Magnetic device for guiding catheter and method of use therefor |
US8437833B2 (en) | 2008-10-07 | 2013-05-07 | Bard Access Systems, Inc. | Percutaneous magnetic gastrostomy |
US20100234841A1 (en) * | 2009-03-10 | 2010-09-16 | Chris Butts | System and Method for Magnetic Tissue Ablation |
EP3542713A1 (en) | 2009-06-12 | 2019-09-25 | Bard Access Systems, Inc. | Adapter for a catheter tip positioning device |
US9532724B2 (en) | 2009-06-12 | 2017-01-03 | Bard Access Systems, Inc. | Apparatus and method for catheter navigation using endovascular energy mapping |
WO2011019760A2 (en) | 2009-08-10 | 2011-02-17 | Romedex International Srl | Devices and methods for endovascular electrography |
EP2517622A3 (en) | 2009-09-29 | 2013-04-24 | C. R. Bard, Inc. | Stylets for use with apparatus for intravascular placement of a catheter |
US11103213B2 (en) | 2009-10-08 | 2021-08-31 | C. R. Bard, Inc. | Spacers for use with an ultrasound probe |
CN102821679B (en) | 2010-02-02 | 2016-04-27 | C·R·巴德股份有限公司 | For the apparatus and method that catheter navigation and end are located |
WO2011103059A2 (en) * | 2010-02-17 | 2011-08-25 | University Of Utah Research Foundation | Cochlear implant insertion method and system |
JP5980201B2 (en) | 2010-05-28 | 2016-08-31 | シー・アール・バード・インコーポレーテッドC R Bard Incorporated | Insertion guidance system for needles and medical components |
WO2011150376A1 (en) | 2010-05-28 | 2011-12-01 | C.R. Bard, Inc. | Apparatus for use with needle insertion guidance system |
US8532743B2 (en) * | 2010-08-05 | 2013-09-10 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Movable magnet for magnetically guided catheter |
JP2013535301A (en) | 2010-08-09 | 2013-09-12 | シー・アール・バード・インコーポレーテッド | Ultrasonic probe head support / cover structure |
BR112013002431B1 (en) | 2010-08-20 | 2021-06-29 | C.R. Bard, Inc | SYSTEM FOR RECONFIRMING THE POSITION OF A CATHETER INSIDE A PATIENT |
EP2632360A4 (en) | 2010-10-29 | 2014-05-21 | Bard Inc C R | Bioimpedance-assisted placement of a medical device |
KR20140051284A (en) | 2011-07-06 | 2014-04-30 | 씨. 알. 바드, 인크. | Needle length determination and calibration for insertion guidance system |
USD699359S1 (en) | 2011-08-09 | 2014-02-11 | C. R. Bard, Inc. | Ultrasound probe head |
USD724745S1 (en) | 2011-08-09 | 2015-03-17 | C. R. Bard, Inc. | Cap for an ultrasound probe |
WO2013070775A1 (en) | 2011-11-07 | 2013-05-16 | C.R. Bard, Inc | Ruggedized ultrasound hydrogel insert |
WO2013188833A2 (en) | 2012-06-15 | 2013-12-19 | C.R. Bard, Inc. | Apparatus and methods for detection of a removable cap on an ultrasound probe |
CN105979868B (en) | 2014-02-06 | 2020-03-10 | C·R·巴德股份有限公司 | Systems and methods for guidance and placement of intravascular devices |
US20150366439A1 (en) * | 2014-06-24 | 2015-12-24 | National Cheng Kung University | Method of operating an endoscope by changing magnetic field and controlling feeding and rotation of the endoscope synchronously |
WO2016094430A1 (en) * | 2014-12-09 | 2016-06-16 | Baylor College Of Medicine | Magnetic assisted in-situ tubular stentgraft fenestration |
US10973584B2 (en) | 2015-01-19 | 2021-04-13 | Bard Access Systems, Inc. | Device and method for vascular access |
US10349890B2 (en) | 2015-06-26 | 2019-07-16 | C. R. Bard, Inc. | Connector interface for ECG-based catheter positioning system |
CN106552296B (en) * | 2015-09-29 | 2020-08-14 | 上海氪励铵勤科技发展有限公司 | Nano particles, preparation method thereof, calculus removing device and application |
CN105268086B (en) * | 2015-11-13 | 2018-03-30 | 中国人民解放军第二军医大学 | Magnetic control guiding wire system |
US11000207B2 (en) | 2016-01-29 | 2021-05-11 | C. R. Bard, Inc. | Multiple coil system for tracking a medical device |
CN106333766B (en) * | 2016-08-16 | 2018-04-10 | 董红霖 | A kind of blood vessel covered stent orthotopic fenestration positioner |
US10992079B2 (en) | 2018-10-16 | 2021-04-27 | Bard Access Systems, Inc. | Safety-equipped connection systems and methods thereof for establishing electrical connections |
JP2022537434A (en) * | 2019-06-20 | 2022-08-25 | イッスム・リサーチ・デベロプメント・カムパニー・オブ・ザ・ヘブリュー・ユニバシティー・オブ・エルサレム リミテッド | Endoscopic retrograde cholangiopancreatography (ERCP) catheter and sensored guidewire and method of using same |
EP4144308A1 (en) | 2021-09-07 | 2023-03-08 | Srinivasan, Shyam | Magnetic device and system for urinary stone extraction using magnet |
Citations (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4063561A (en) * | 1975-08-25 | 1977-12-20 | The Signal Companies, Inc. | Direction control device for endotracheal tube |
US4244362A (en) * | 1978-11-29 | 1981-01-13 | Anderson Charles C | Endotracheal tube control device |
US5353807A (en) * | 1992-12-07 | 1994-10-11 | Demarco Thomas J | Magnetically guidable intubation device |
US5429131A (en) * | 1994-02-25 | 1995-07-04 | The Regents Of The University Of California | Magnetized electrode tip catheter |
US5654864A (en) * | 1994-07-25 | 1997-08-05 | University Of Virginia Patent Foundation | Control method for magnetic stereotaxis system |
US5843153A (en) * | 1997-07-15 | 1998-12-01 | Sulzer Intermedics Inc. | Steerable endocardial lead using magnetostrictive material and a magnetic field |
US5931818A (en) * | 1997-08-29 | 1999-08-03 | Stereotaxis, Inc. | Method of and apparatus for intraparenchymal positioning of medical devices |
US6014580A (en) * | 1997-11-12 | 2000-01-11 | Stereotaxis, Inc. | Device and method for specifying magnetic field for surgical applications |
US6128174A (en) * | 1997-08-29 | 2000-10-03 | Stereotaxis, Inc. | Method and apparatus for rapidly changing a magnetic field produced by electromagnets |
US6148823A (en) * | 1999-03-17 | 2000-11-21 | Stereotaxis, Inc. | Method of and system for controlling magnetic elements in the body using a gapped toroid magnet |
US6152933A (en) * | 1997-11-12 | 2000-11-28 | Stereotaxis, Inc. | Intracranial bolt and method of placing and using an intracranial bolt to position a medical device |
US6157853A (en) * | 1997-11-12 | 2000-12-05 | Stereotaxis, Inc. | Method and apparatus using shaped field of repositionable magnet to guide implant |
US6212419B1 (en) * | 1997-11-12 | 2001-04-03 | Walter M. Blume | Method and apparatus using shaped field of repositionable magnet to guide implant |
US6241671B1 (en) * | 1998-11-03 | 2001-06-05 | Stereotaxis, Inc. | Open field system for magnetic surgery |
US6292678B1 (en) * | 1999-05-13 | 2001-09-18 | Stereotaxis, Inc. | Method of magnetically navigating medical devices with magnetic fields and gradients, and medical devices adapted therefor |
US6298257B1 (en) * | 1999-09-22 | 2001-10-02 | Sterotaxis, Inc. | Cardiac methods and system |
US6296604B1 (en) * | 1999-03-17 | 2001-10-02 | Stereotaxis, Inc. | Methods of and compositions for treating vascular defects |
US6315709B1 (en) * | 1998-08-07 | 2001-11-13 | Stereotaxis, Inc. | Magnetic vascular defect treatment system |
US6330467B1 (en) * | 1999-02-04 | 2001-12-11 | Stereotaxis, Inc. | Efficient magnet system for magnetically-assisted surgery |
US20020019644A1 (en) * | 1999-07-12 | 2002-02-14 | Hastings Roger N. | Magnetically guided atherectomy |
US6352363B1 (en) * | 2001-01-16 | 2002-03-05 | Stereotaxis, Inc. | Shielded x-ray source, method of shielding an x-ray source, and magnetic surgical system with shielded x-ray source |
US6375606B1 (en) * | 1999-03-17 | 2002-04-23 | Stereotaxis, Inc. | Methods of and apparatus for treating vascular defects |
US6385472B1 (en) * | 1999-09-10 | 2002-05-07 | Stereotaxis, Inc. | Magnetically navigable telescoping catheter and method of navigating telescoping catheter |
US6401723B1 (en) * | 2000-02-16 | 2002-06-11 | Stereotaxis, Inc. | Magnetic medical devices with changeable magnetic moments and method of navigating magnetic medical devices with changeable magnetic moments |
US6428551B1 (en) * | 1999-03-30 | 2002-08-06 | Stereotaxis, Inc. | Magnetically navigable and/or controllable device for removing material from body lumens and cavities |
US6459924B1 (en) * | 1997-11-12 | 2002-10-01 | Stereotaxis, Inc. | Articulated magnetic guidance systems and devices and methods for using same for magnetically-assisted surgery |
US20020177789A1 (en) * | 2001-05-06 | 2002-11-28 | Ferry Steven J. | System and methods for advancing a catheter |
US6505062B1 (en) * | 1998-02-09 | 2003-01-07 | Stereotaxis, Inc. | Method for locating magnetic implant by source field |
US6522909B1 (en) * | 1998-08-07 | 2003-02-18 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling catheters in body lumens and cavities |
US6524303B1 (en) * | 2000-09-08 | 2003-02-25 | Stereotaxis, Inc. | Variable stiffness magnetic catheter |
US6527782B2 (en) * | 2000-06-07 | 2003-03-04 | Sterotaxis, Inc. | Guide for medical devices |
US6537196B1 (en) * | 2000-10-24 | 2003-03-25 | Stereotaxis, Inc. | Magnet assembly with variable field directions and methods of magnetically navigating medical objects |
US6562019B1 (en) * | 1999-09-20 | 2003-05-13 | Stereotaxis, Inc. | Method of utilizing a magnetically guided myocardial treatment system |
US6662034B2 (en) * | 2000-11-15 | 2003-12-09 | Stereotaxis, Inc. | Magnetically guidable electrophysiology catheter |
US6677752B1 (en) * | 2000-11-20 | 2004-01-13 | Stereotaxis, Inc. | Close-in shielding system for magnetic medical treatment instruments |
US20040019447A1 (en) * | 2002-07-16 | 2004-01-29 | Yehoshua Shachar | Apparatus and method for catheter guidance control and imaging |
US6702804B1 (en) * | 1999-10-04 | 2004-03-09 | Stereotaxis, Inc. | Method for safely and efficiently navigating magnetic devices in the body |
US20040068173A1 (en) * | 2002-08-06 | 2004-04-08 | Viswanathan Raju R. | Remote control of medical devices using a virtual device interface |
US6733511B2 (en) * | 1998-10-02 | 2004-05-11 | Stereotaxis, Inc. | Magnetically navigable and/or controllable device for removing material from body lumens and cavities |
US20040096511A1 (en) * | 2002-07-03 | 2004-05-20 | Jonathan Harburn | Magnetically guidable carriers and methods for the targeted magnetic delivery of substances in the body |
US20040133130A1 (en) * | 2003-01-06 | 2004-07-08 | Ferry Steven J. | Magnetically navigable medical guidewire |
US20040157082A1 (en) * | 2002-07-22 | 2004-08-12 | Ritter Rogers C. | Coated magnetically responsive particles, and embolic materials using coated magnetically responsive particles |
US20040158972A1 (en) * | 2002-11-07 | 2004-08-19 | Creighton Francis M. | Method of making a compound magnet |
US20040186376A1 (en) * | 2002-09-30 | 2004-09-23 | Hogg Bevil J. | Method and apparatus for improved surgical navigation employing electronic identification with automatically actuated flexible medical devices |
US6817364B2 (en) * | 2000-07-24 | 2004-11-16 | Stereotaxis, Inc. | Magnetically navigated pacing leads, and methods for delivering medical devices |
US20040249262A1 (en) * | 2003-03-13 | 2004-12-09 | Werp Peter R. | Magnetic navigation system |
US20040249263A1 (en) * | 2003-03-13 | 2004-12-09 | Creighton Francis M. | Magnetic navigation system and magnet system therefor |
US6834201B2 (en) * | 2001-01-29 | 2004-12-21 | Stereotaxis, Inc. | Catheter navigation within an MR imaging device |
US20040260172A1 (en) * | 2003-04-24 | 2004-12-23 | Ritter Rogers C. | Magnetic navigation of medical devices in magnetic fields |
US20050020911A1 (en) * | 2002-04-10 | 2005-01-27 | Viswanathan Raju R. | Efficient closed loop feedback navigation |
US20050043611A1 (en) * | 2003-05-02 | 2005-02-24 | Sabo Michael E. | Variable magnetic moment MR navigation |
US20050065435A1 (en) * | 2003-07-22 | 2005-03-24 | John Rauch | User interface for remote control of medical devices |
US20050096589A1 (en) * | 2003-10-20 | 2005-05-05 | Yehoshua Shachar | System and method for radar-assisted catheter guidance and control |
US20050113812A1 (en) * | 2003-09-16 | 2005-05-26 | Viswanathan Raju R. | User interface for remote control of medical devices |
US20050113628A1 (en) * | 2002-01-23 | 2005-05-26 | Creighton Francis M.Iv | Rotating and pivoting magnet for magnetic navigation |
US20050119687A1 (en) * | 2003-09-08 | 2005-06-02 | Dacey Ralph G.Jr. | Methods of, and materials for, treating vascular defects with magnetically controllable hydrogels |
US6902528B1 (en) * | 1999-04-14 | 2005-06-07 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling endoscopes in body lumens and cavities |
US20050182315A1 (en) * | 2003-11-07 | 2005-08-18 | Ritter Rogers C. | Magnetic resonance imaging and magnetic navigation systems and methods |
US20050256398A1 (en) * | 2004-05-12 | 2005-11-17 | Hastings Roger N | Systems and methods for interventional medicine |
US6968846B2 (en) * | 2002-03-07 | 2005-11-29 | Stereotaxis, Inc. | Method and apparatus for refinably accurate localization of devices and instruments in scattering environments |
US6975197B2 (en) * | 2002-01-23 | 2005-12-13 | Stereotaxis, Inc. | Rotating and pivoting magnet for magnetic navigation |
US6980843B2 (en) * | 2003-05-21 | 2005-12-27 | Stereotaxis, Inc. | Electrophysiology catheter |
US20060009735A1 (en) * | 2004-06-29 | 2006-01-12 | Viswanathan Raju R | Navigation of remotely actuable medical device using control variable and length |
US20060025679A1 (en) * | 2004-06-04 | 2006-02-02 | Viswanathan Raju R | User interface for remote control of medical devices |
US20060036163A1 (en) * | 2004-07-19 | 2006-02-16 | Viswanathan Raju R | Method of, and apparatus for, controlling medical navigation systems |
US20060041245A1 (en) * | 2001-05-06 | 2006-02-23 | Ferry Steven J | Systems and methods for medical device a dvancement and rotation |
US7008418B2 (en) * | 2002-05-09 | 2006-03-07 | Stereotaxis, Inc. | Magnetically assisted pulmonary vein isolation |
US20060058646A1 (en) * | 2004-08-26 | 2006-03-16 | Raju Viswanathan | Method for surgical navigation utilizing scale-invariant registration between a navigation system and a localization system |
US7019610B2 (en) * | 2002-01-23 | 2006-03-28 | Stereotaxis, Inc. | Magnetic navigation system |
US7020512B2 (en) * | 2002-01-14 | 2006-03-28 | Stereotaxis, Inc. | Method of localizing medical devices |
US20060074297A1 (en) * | 2004-08-24 | 2006-04-06 | Viswanathan Raju R | Methods and apparatus for steering medical devices in body lumens |
US20060079745A1 (en) * | 2004-10-07 | 2006-04-13 | Viswanathan Raju R | Surgical navigation with overlay on anatomical images |
US20060079812A1 (en) * | 2004-09-07 | 2006-04-13 | Viswanathan Raju R | Magnetic guidewire for lesion crossing |
US20060093193A1 (en) * | 2004-10-29 | 2006-05-04 | Viswanathan Raju R | Image-based medical device localization |
US20060094956A1 (en) * | 2004-10-29 | 2006-05-04 | Viswanathan Raju R | Restricted navigation controller for, and methods of controlling, a remote navigation system |
US20060100505A1 (en) * | 2004-10-26 | 2006-05-11 | Viswanathan Raju R | Surgical navigation using a three-dimensional user interface |
US7066924B1 (en) * | 1997-11-12 | 2006-06-27 | Stereotaxis, Inc. | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
US20060144408A1 (en) * | 2004-07-23 | 2006-07-06 | Ferry Steven J | Micro-catheter device and method of using same |
US20060144407A1 (en) * | 2004-07-20 | 2006-07-06 | Anthony Aliberto | Magnetic navigation manipulation apparatus |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4671287A (en) | 1983-12-29 | 1987-06-09 | Fiddian Green Richard G | Apparatus and method for sustaining vitality of organs of the gastrointestinal tract |
US5630427A (en) | 1992-08-12 | 1997-05-20 | Scimed Life Systems, Inc. | Medical shaft movement control device and method |
US5623943A (en) | 1992-08-12 | 1997-04-29 | Scimed Life Systems, Inc. | Magnetic medical shaft movement control device and method |
US5425382A (en) * | 1993-09-14 | 1995-06-20 | University Of Washington | Apparatus and method for locating a medical tube in the body of a patient |
US5902238A (en) * | 1993-09-14 | 1999-05-11 | University Of Washington | Medical tube and apparatus for locating the same in the body of a patient |
US5464023A (en) * | 1994-01-31 | 1995-11-07 | Cordis Corporation | Magnetic exchange device for catheters |
US5706827A (en) | 1994-09-21 | 1998-01-13 | Scimed Life Systems, Inc. | Magnetic lumen catheter |
US5431640A (en) * | 1994-11-09 | 1995-07-11 | The Medical Center Of Central Georgia | Method and apparatus for duodenal intubation of a patient |
US5636644A (en) | 1995-03-17 | 1997-06-10 | Applied Medical Resources Corporation | Method and apparatus for endoconduit targeting |
US5647843A (en) | 1996-05-24 | 1997-07-15 | Vance Products Incorporated | Anti-reflux ureteral stent |
-
1998
- 1998-11-25 US US09/200,055 patent/US7066924B1/en not_active Expired - Lifetime
-
2006
- 2006-06-27 US US11/475,840 patent/US20070021731A1/en not_active Abandoned
Patent Citations (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4063561A (en) * | 1975-08-25 | 1977-12-20 | The Signal Companies, Inc. | Direction control device for endotracheal tube |
US4244362A (en) * | 1978-11-29 | 1981-01-13 | Anderson Charles C | Endotracheal tube control device |
US5353807A (en) * | 1992-12-07 | 1994-10-11 | Demarco Thomas J | Magnetically guidable intubation device |
US5429131A (en) * | 1994-02-25 | 1995-07-04 | The Regents Of The University Of California | Magnetized electrode tip catheter |
US5654864A (en) * | 1994-07-25 | 1997-08-05 | University Of Virginia Patent Foundation | Control method for magnetic stereotaxis system |
US5843153A (en) * | 1997-07-15 | 1998-12-01 | Sulzer Intermedics Inc. | Steerable endocardial lead using magnetostrictive material and a magnetic field |
US6128174A (en) * | 1997-08-29 | 2000-10-03 | Stereotaxis, Inc. | Method and apparatus for rapidly changing a magnetic field produced by electromagnets |
US5931818A (en) * | 1997-08-29 | 1999-08-03 | Stereotaxis, Inc. | Method of and apparatus for intraparenchymal positioning of medical devices |
US6015414A (en) * | 1997-08-29 | 2000-01-18 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling motion direction of a mechanically pushed catheter |
US6157853A (en) * | 1997-11-12 | 2000-12-05 | Stereotaxis, Inc. | Method and apparatus using shaped field of repositionable magnet to guide implant |
US7066924B1 (en) * | 1997-11-12 | 2006-06-27 | Stereotaxis, Inc. | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
US6152933A (en) * | 1997-11-12 | 2000-11-28 | Stereotaxis, Inc. | Intracranial bolt and method of placing and using an intracranial bolt to position a medical device |
US6212419B1 (en) * | 1997-11-12 | 2001-04-03 | Walter M. Blume | Method and apparatus using shaped field of repositionable magnet to guide implant |
US6459924B1 (en) * | 1997-11-12 | 2002-10-01 | Stereotaxis, Inc. | Articulated magnetic guidance systems and devices and methods for using same for magnetically-assisted surgery |
US6507751B2 (en) * | 1997-11-12 | 2003-01-14 | Stereotaxis, Inc. | Method and apparatus using shaped field of repositionable magnet to guide implant |
US6014580A (en) * | 1997-11-12 | 2000-01-11 | Stereotaxis, Inc. | Device and method for specifying magnetic field for surgical applications |
US6304768B1 (en) * | 1997-11-12 | 2001-10-16 | Stereotaxis, Inc. | Method and apparatus using shaped field of repositionable magnet to guide implant |
US7010338B2 (en) * | 1998-02-09 | 2006-03-07 | Stereotaxis, Inc. | Device for locating magnetic implant by source field |
US6505062B1 (en) * | 1998-02-09 | 2003-01-07 | Stereotaxis, Inc. | Method for locating magnetic implant by source field |
US6522909B1 (en) * | 1998-08-07 | 2003-02-18 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling catheters in body lumens and cavities |
US6315709B1 (en) * | 1998-08-07 | 2001-11-13 | Stereotaxis, Inc. | Magnetic vascular defect treatment system |
US6733511B2 (en) * | 1998-10-02 | 2004-05-11 | Stereotaxis, Inc. | Magnetically navigable and/or controllable device for removing material from body lumens and cavities |
US20010038683A1 (en) * | 1998-11-03 | 2001-11-08 | Ritter Rogers C. | Open field system for magnetic surgery |
US6241671B1 (en) * | 1998-11-03 | 2001-06-05 | Stereotaxis, Inc. | Open field system for magnetic surgery |
US6330467B1 (en) * | 1999-02-04 | 2001-12-11 | Stereotaxis, Inc. | Efficient magnet system for magnetically-assisted surgery |
US20040064153A1 (en) * | 1999-02-04 | 2004-04-01 | Creighton Francis M. | Efficient magnet system for magnetically-assisted surgery |
US6630879B1 (en) * | 1999-02-04 | 2003-10-07 | Stereotaxis, Inc. | Efficient magnet system for magnetically-assisted surgery |
US6148823A (en) * | 1999-03-17 | 2000-11-21 | Stereotaxis, Inc. | Method of and system for controlling magnetic elements in the body using a gapped toroid magnet |
US6364823B1 (en) * | 1999-03-17 | 2002-04-02 | Stereotaxis, Inc. | Methods of and compositions for treating vascular defects |
US6296604B1 (en) * | 1999-03-17 | 2001-10-02 | Stereotaxis, Inc. | Methods of and compositions for treating vascular defects |
US6375606B1 (en) * | 1999-03-17 | 2002-04-23 | Stereotaxis, Inc. | Methods of and apparatus for treating vascular defects |
US6428551B1 (en) * | 1999-03-30 | 2002-08-06 | Stereotaxis, Inc. | Magnetically navigable and/or controllable device for removing material from body lumens and cavities |
US6902528B1 (en) * | 1999-04-14 | 2005-06-07 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling endoscopes in body lumens and cavities |
US6542766B2 (en) * | 1999-05-13 | 2003-04-01 | Andrew F. Hall | Medical devices adapted for magnetic navigation with magnetic fields and gradients |
US6292678B1 (en) * | 1999-05-13 | 2001-09-18 | Stereotaxis, Inc. | Method of magnetically navigating medical devices with magnetic fields and gradients, and medical devices adapted therefor |
US20020019644A1 (en) * | 1999-07-12 | 2002-02-14 | Hastings Roger N. | Magnetically guided atherectomy |
US6911026B1 (en) * | 1999-07-12 | 2005-06-28 | Stereotaxis, Inc. | Magnetically guided atherectomy |
US6385472B1 (en) * | 1999-09-10 | 2002-05-07 | Stereotaxis, Inc. | Magnetically navigable telescoping catheter and method of navigating telescoping catheter |
US6562019B1 (en) * | 1999-09-20 | 2003-05-13 | Stereotaxis, Inc. | Method of utilizing a magnetically guided myocardial treatment system |
US20040006301A1 (en) * | 1999-09-20 | 2004-01-08 | Sell Jonathan C. | Magnetically guided myocardial treatment system |
US6298257B1 (en) * | 1999-09-22 | 2001-10-02 | Sterotaxis, Inc. | Cardiac methods and system |
US6755816B2 (en) * | 1999-10-04 | 2004-06-29 | Stereotaxis, Inc. | Method for safely and efficiently navigating magnetic devices in the body |
US20040199074A1 (en) * | 1999-10-04 | 2004-10-07 | Ritter Rogers C. | Method for safely and efficiently navigating magnetic devices in the body |
US6702804B1 (en) * | 1999-10-04 | 2004-03-09 | Stereotaxis, Inc. | Method for safely and efficiently navigating magnetic devices in the body |
US6401723B1 (en) * | 2000-02-16 | 2002-06-11 | Stereotaxis, Inc. | Magnetic medical devices with changeable magnetic moments and method of navigating magnetic medical devices with changeable magnetic moments |
US6527782B2 (en) * | 2000-06-07 | 2003-03-04 | Sterotaxis, Inc. | Guide for medical devices |
US6817364B2 (en) * | 2000-07-24 | 2004-11-16 | Stereotaxis, Inc. | Magnetically navigated pacing leads, and methods for delivering medical devices |
US6524303B1 (en) * | 2000-09-08 | 2003-02-25 | Stereotaxis, Inc. | Variable stiffness magnetic catheter |
US6537196B1 (en) * | 2000-10-24 | 2003-03-25 | Stereotaxis, Inc. | Magnet assembly with variable field directions and methods of magnetically navigating medical objects |
US6662034B2 (en) * | 2000-11-15 | 2003-12-09 | Stereotaxis, Inc. | Magnetically guidable electrophysiology catheter |
US6677752B1 (en) * | 2000-11-20 | 2004-01-13 | Stereotaxis, Inc. | Close-in shielding system for magnetic medical treatment instruments |
US6352363B1 (en) * | 2001-01-16 | 2002-03-05 | Stereotaxis, Inc. | Shielded x-ray source, method of shielding an x-ray source, and magnetic surgical system with shielded x-ray source |
US6834201B2 (en) * | 2001-01-29 | 2004-12-21 | Stereotaxis, Inc. | Catheter navigation within an MR imaging device |
US20060041245A1 (en) * | 2001-05-06 | 2006-02-23 | Ferry Steven J | Systems and methods for medical device a dvancement and rotation |
US20020177789A1 (en) * | 2001-05-06 | 2002-11-28 | Ferry Steven J. | System and methods for advancing a catheter |
US7020512B2 (en) * | 2002-01-14 | 2006-03-28 | Stereotaxis, Inc. | Method of localizing medical devices |
US7019610B2 (en) * | 2002-01-23 | 2006-03-28 | Stereotaxis, Inc. | Magnetic navigation system |
US6975197B2 (en) * | 2002-01-23 | 2005-12-13 | Stereotaxis, Inc. | Rotating and pivoting magnet for magnetic navigation |
US20050113628A1 (en) * | 2002-01-23 | 2005-05-26 | Creighton Francis M.Iv | Rotating and pivoting magnet for magnetic navigation |
US6968846B2 (en) * | 2002-03-07 | 2005-11-29 | Stereotaxis, Inc. | Method and apparatus for refinably accurate localization of devices and instruments in scattering environments |
US20050020911A1 (en) * | 2002-04-10 | 2005-01-27 | Viswanathan Raju R. | Efficient closed loop feedback navigation |
US7008418B2 (en) * | 2002-05-09 | 2006-03-07 | Stereotaxis, Inc. | Magnetically assisted pulmonary vein isolation |
US20040096511A1 (en) * | 2002-07-03 | 2004-05-20 | Jonathan Harburn | Magnetically guidable carriers and methods for the targeted magnetic delivery of substances in the body |
US20060116633A1 (en) * | 2002-07-16 | 2006-06-01 | Yehoshua Shachar | System and method for a magnetic catheter tip |
US20060114088A1 (en) * | 2002-07-16 | 2006-06-01 | Yehoshua Shachar | Apparatus and method for generating a magnetic field |
US20040019447A1 (en) * | 2002-07-16 | 2004-01-29 | Yehoshua Shachar | Apparatus and method for catheter guidance control and imaging |
US20040157082A1 (en) * | 2002-07-22 | 2004-08-12 | Ritter Rogers C. | Coated magnetically responsive particles, and embolic materials using coated magnetically responsive particles |
US20040068173A1 (en) * | 2002-08-06 | 2004-04-08 | Viswanathan Raju R. | Remote control of medical devices using a virtual device interface |
US20040186376A1 (en) * | 2002-09-30 | 2004-09-23 | Hogg Bevil J. | Method and apparatus for improved surgical navigation employing electronic identification with automatically actuated flexible medical devices |
US20040158972A1 (en) * | 2002-11-07 | 2004-08-19 | Creighton Francis M. | Method of making a compound magnet |
US20040133130A1 (en) * | 2003-01-06 | 2004-07-08 | Ferry Steven J. | Magnetically navigable medical guidewire |
US20040249262A1 (en) * | 2003-03-13 | 2004-12-09 | Werp Peter R. | Magnetic navigation system |
US20040249263A1 (en) * | 2003-03-13 | 2004-12-09 | Creighton Francis M. | Magnetic navigation system and magnet system therefor |
US20040260172A1 (en) * | 2003-04-24 | 2004-12-23 | Ritter Rogers C. | Magnetic navigation of medical devices in magnetic fields |
US20050043611A1 (en) * | 2003-05-02 | 2005-02-24 | Sabo Michael E. | Variable magnetic moment MR navigation |
US6980843B2 (en) * | 2003-05-21 | 2005-12-27 | Stereotaxis, Inc. | Electrophysiology catheter |
US20050065435A1 (en) * | 2003-07-22 | 2005-03-24 | John Rauch | User interface for remote control of medical devices |
US20050119687A1 (en) * | 2003-09-08 | 2005-06-02 | Dacey Ralph G.Jr. | Methods of, and materials for, treating vascular defects with magnetically controllable hydrogels |
US20050113812A1 (en) * | 2003-09-16 | 2005-05-26 | Viswanathan Raju R. | User interface for remote control of medical devices |
US20050096589A1 (en) * | 2003-10-20 | 2005-05-05 | Yehoshua Shachar | System and method for radar-assisted catheter guidance and control |
US20050182315A1 (en) * | 2003-11-07 | 2005-08-18 | Ritter Rogers C. | Magnetic resonance imaging and magnetic navigation systems and methods |
US20050256398A1 (en) * | 2004-05-12 | 2005-11-17 | Hastings Roger N | Systems and methods for interventional medicine |
US20060041178A1 (en) * | 2004-06-04 | 2006-02-23 | Viswanathan Raju R | User interface for remote control of medical devices |
US20060025679A1 (en) * | 2004-06-04 | 2006-02-02 | Viswanathan Raju R | User interface for remote control of medical devices |
US20060041180A1 (en) * | 2004-06-04 | 2006-02-23 | Viswanathan Raju R | User interface for remote control of medical devices |
US20060041179A1 (en) * | 2004-06-04 | 2006-02-23 | Viswanathan Raju R | User interface for remote control of medical devices |
US20060041181A1 (en) * | 2004-06-04 | 2006-02-23 | Viswanathan Raju R | User interface for remote control of medical devices |
US20060036125A1 (en) * | 2004-06-04 | 2006-02-16 | Viswanathan Raju R | User interface for remote control of medical devices |
US20060009735A1 (en) * | 2004-06-29 | 2006-01-12 | Viswanathan Raju R | Navigation of remotely actuable medical device using control variable and length |
US20060036163A1 (en) * | 2004-07-19 | 2006-02-16 | Viswanathan Raju R | Method of, and apparatus for, controlling medical navigation systems |
US20060144407A1 (en) * | 2004-07-20 | 2006-07-06 | Anthony Aliberto | Magnetic navigation manipulation apparatus |
US20060144408A1 (en) * | 2004-07-23 | 2006-07-06 | Ferry Steven J | Micro-catheter device and method of using same |
US20060074297A1 (en) * | 2004-08-24 | 2006-04-06 | Viswanathan Raju R | Methods and apparatus for steering medical devices in body lumens |
US20060058646A1 (en) * | 2004-08-26 | 2006-03-16 | Raju Viswanathan | Method for surgical navigation utilizing scale-invariant registration between a navigation system and a localization system |
US20060079812A1 (en) * | 2004-09-07 | 2006-04-13 | Viswanathan Raju R | Magnetic guidewire for lesion crossing |
US20060079745A1 (en) * | 2004-10-07 | 2006-04-13 | Viswanathan Raju R | Surgical navigation with overlay on anatomical images |
US20060100505A1 (en) * | 2004-10-26 | 2006-05-11 | Viswanathan Raju R | Surgical navigation using a three-dimensional user interface |
US20060093193A1 (en) * | 2004-10-29 | 2006-05-04 | Viswanathan Raju R | Image-based medical device localization |
US20060094956A1 (en) * | 2004-10-29 | 2006-05-04 | Viswanathan Raju R | Restricted navigation controller for, and methods of controlling, a remote navigation system |
Cited By (128)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070287909A1 (en) * | 1998-08-07 | 2007-12-13 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling catheters in body lumens and cavities |
US20100063385A1 (en) * | 1998-08-07 | 2010-03-11 | Garibaldi Jeffrey M | Method and apparatus for magnetically controlling catheters in body lumens and cavities |
US20090177032A1 (en) * | 1999-04-14 | 2009-07-09 | Garibaldi Jeffrey M | Method and apparatus for magnetically controlling endoscopes in body lumens and cavities |
US20080047568A1 (en) * | 1999-10-04 | 2008-02-28 | Ritter Rogers C | Method for Safely and Efficiently Navigating Magnetic Devices in the Body |
US7757694B2 (en) | 1999-10-04 | 2010-07-20 | Stereotaxis, Inc. | Method for safely and efficiently navigating magnetic devices in the body |
US7966059B2 (en) | 1999-10-04 | 2011-06-21 | Stereotaxis, Inc. | Rotating and pivoting magnet for magnetic navigation |
US7771415B2 (en) | 1999-10-04 | 2010-08-10 | Stereotaxis, Inc. | Method for safely and efficiently navigating magnetic devices in the body |
US20100163061A1 (en) * | 2000-04-11 | 2010-07-01 | Creighton Francis M | Magnets with varying magnetization direction and method of making such magnets |
US20080016677A1 (en) * | 2002-01-23 | 2008-01-24 | Stereotaxis, Inc. | Rotating and pivoting magnet for magnetic navigation |
US20040169316A1 (en) * | 2002-03-28 | 2004-09-02 | Siliconix Taiwan Ltd. | Encapsulation method and leadframe for leadless semiconductor packages |
US20080077007A1 (en) * | 2002-06-28 | 2008-03-27 | Hastings Roger N | Method of Navigating Medical Devices in the Presence of Radiopaque Material |
US8060184B2 (en) | 2002-06-28 | 2011-11-15 | Stereotaxis, Inc. | Method of navigating medical devices in the presence of radiopaque material |
US8196590B2 (en) | 2003-05-02 | 2012-06-12 | Stereotaxis, Inc. | Variable magnetic moment MR navigation |
US20050113812A1 (en) * | 2003-09-16 | 2005-05-26 | Viswanathan Raju R. | User interface for remote control of medical devices |
US20110022029A1 (en) * | 2004-12-20 | 2011-01-27 | Viswanathan Raju R | Contact over-torque with three-dimensional anatomical data |
US8369934B2 (en) | 2004-12-20 | 2013-02-05 | Stereotaxis, Inc. | Contact over-torque with three-dimensional anatomical data |
US20060270915A1 (en) * | 2005-01-11 | 2006-11-30 | Ritter Rogers C | Navigation using sensed physiological data as feedback |
US7708696B2 (en) | 2005-01-11 | 2010-05-04 | Stereotaxis, Inc. | Navigation using sensed physiological data as feedback |
US20110033100A1 (en) * | 2005-02-07 | 2011-02-10 | Viswanathan Raju R | Registration of three-dimensional image data to 2d-image-derived data |
US7961926B2 (en) | 2005-02-07 | 2011-06-14 | Stereotaxis, Inc. | Registration of three-dimensional image data to 2D-image-derived data |
US20070060992A1 (en) * | 2005-06-02 | 2007-03-15 | Carlo Pappone | Methods and devices for mapping the ventricle for pacing lead placement and therapy delivery |
US9314222B2 (en) | 2005-07-07 | 2016-04-19 | Stereotaxis, Inc. | Operation of a remote medical navigation system using ultrasound image |
US20090062646A1 (en) * | 2005-07-07 | 2009-03-05 | Creighton Iv Francis M | Operation of a remote medical navigation system using ultrasound image |
US20070060966A1 (en) * | 2005-07-11 | 2007-03-15 | Carlo Pappone | Method of treating cardiac arrhythmias |
US7769444B2 (en) | 2005-07-11 | 2010-08-03 | Stereotaxis, Inc. | Method of treating cardiac arrhythmias |
US20070016131A1 (en) * | 2005-07-12 | 2007-01-18 | Munger Gareth T | Flexible magnets for navigable medical devices |
US20070060829A1 (en) * | 2005-07-21 | 2007-03-15 | Carlo Pappone | Method of finding the source of and treating cardiac arrhythmias |
US20070062547A1 (en) * | 2005-07-21 | 2007-03-22 | Carlo Pappone | Systems for and methods of tissue ablation |
US7818076B2 (en) | 2005-07-26 | 2010-10-19 | Stereotaxis, Inc. | Method and apparatus for multi-system remote surgical navigation from a single control center |
US20070060962A1 (en) * | 2005-07-26 | 2007-03-15 | Carlo Pappone | Apparatus and methods for cardiac resynchronization therapy and cardiac contractility modulation |
US7772950B2 (en) | 2005-08-10 | 2010-08-10 | Stereotaxis, Inc. | Method and apparatus for dynamic magnetic field control using multiple magnets |
US20070167720A1 (en) * | 2005-12-06 | 2007-07-19 | Viswanathan Raju R | Smart card control of medical devices |
US20070149946A1 (en) * | 2005-12-07 | 2007-06-28 | Viswanathan Raju R | Advancer system for coaxial medical devices |
US20070161882A1 (en) * | 2006-01-06 | 2007-07-12 | Carlo Pappone | Electrophysiology catheter and system for gentle and firm wall contact |
US20100168549A1 (en) * | 2006-01-06 | 2010-07-01 | Carlo Pappone | Electrophysiology catheter and system for gentle and firm wall contact |
US20070179492A1 (en) * | 2006-01-06 | 2007-08-02 | Carlo Pappone | Electrophysiology catheter and system for gentle and firm wall contact |
US20080015670A1 (en) * | 2006-01-17 | 2008-01-17 | Carlo Pappone | Methods and devices for cardiac ablation |
US20070197899A1 (en) * | 2006-01-17 | 2007-08-23 | Ritter Rogers C | Apparatus and method for magnetic navigation using boost magnets |
US20070197906A1 (en) * | 2006-01-24 | 2007-08-23 | Ritter Rogers C | Magnetic field shape-adjustable medical device and method of using the same |
US20070250041A1 (en) * | 2006-04-19 | 2007-10-25 | Werp Peter R | Extendable Interventional Medical Devices |
US7526337B2 (en) | 2006-06-06 | 2009-04-28 | Cardiac Pacemakers, Inc. | Method and device for lymphatic system monitoring |
US20070282380A1 (en) * | 2006-06-06 | 2007-12-06 | Cardiac Pacemakers | Cardiac stimulation and sensing with endolymphatically implanted lead |
US20100217346A1 (en) * | 2006-06-06 | 2010-08-26 | Shuros Allan C | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
US8369943B2 (en) | 2006-06-06 | 2013-02-05 | Cardiac Pacemakers, Inc. | Method and apparatus for neural stimulation via the lymphatic system |
US8126538B2 (en) | 2006-06-06 | 2012-02-28 | Cardiac Pacemakers, Inc. | Method and apparatus for introducing endolymphatic instrumentation |
US20070282382A1 (en) * | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and device for lymphatic system monitoring |
US20070282376A1 (en) * | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and apparatus for neural stimulation via the lymphatic system |
US8897878B2 (en) | 2006-06-06 | 2014-11-25 | Cardiac Pacemakers, Inc. | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
US20070282386A1 (en) * | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
US7734341B2 (en) | 2006-06-06 | 2010-06-08 | Cardiac Pacemakers, Inc. | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
US20080009719A1 (en) * | 2006-06-06 | 2008-01-10 | Shuros Allan C | Method and apparatus for introducing endolymphatic instrumentation |
US7894906B2 (en) | 2006-06-06 | 2011-02-22 | Cardiac Pacemakers, Inc. | Amelioration of chronic pain by endolymphatic stimulation |
US7761157B2 (en) | 2006-06-06 | 2010-07-20 | Cardiac Pacemakers, Inc. | Cardiac stimulation and sensing with endolymphatically implanted lead |
US20100042170A1 (en) * | 2006-06-06 | 2010-02-18 | Shuros Allan C | Method and apparatus for neural stimulation via the lymphatic system |
WO2007146493A1 (en) * | 2006-06-06 | 2007-12-21 | Cardiac Pacemakers, Inc. | Method and apparatus for introducing endolymphatic instrumentation |
US20090228059A1 (en) * | 2006-06-06 | 2009-09-10 | Shuros Allan C | Method and device for lymphatic system monitoring |
US20080039830A1 (en) * | 2006-08-14 | 2008-02-14 | Munger Gareth T | Method and Apparatus for Ablative Recanalization of Blocked Vasculature |
US7961924B2 (en) | 2006-08-21 | 2011-06-14 | Stereotaxis, Inc. | Method of three-dimensional device localization using single-plane imaging |
US20100222669A1 (en) * | 2006-08-23 | 2010-09-02 | William Flickinger | Medical device guide |
US8905999B2 (en) | 2006-09-01 | 2014-12-09 | Cardiac Pacemakers, Inc. | Method and apparatus for endolymphatic drug delivery |
US20080097412A1 (en) * | 2006-09-01 | 2008-04-24 | Shuros Allan C | Method and apparatus for endolymphatic drug delivery |
US20100097315A1 (en) * | 2006-09-06 | 2010-04-22 | Garibaldi Jeffrey M | Global input device for multiple computer-controlled medical systems |
US20080059598A1 (en) * | 2006-09-06 | 2008-03-06 | Garibaldi Jeffrey M | Coordinated Control for Multiple Computer-Controlled Medical Systems |
US7747960B2 (en) | 2006-09-06 | 2010-06-29 | Stereotaxis, Inc. | Control for, and method of, operating at least two medical systems |
US20080055239A1 (en) * | 2006-09-06 | 2008-03-06 | Garibaldi Jeffrey M | Global Input Device for Multiple Computer-Controlled Medical Systems |
US20080058609A1 (en) * | 2006-09-06 | 2008-03-06 | Stereotaxis, Inc. | Workflow driven method of performing multi-step medical procedures |
US20080064933A1 (en) * | 2006-09-06 | 2008-03-13 | Stereotaxis, Inc. | Workflow driven display for medical procedures |
US8242972B2 (en) | 2006-09-06 | 2012-08-14 | Stereotaxis, Inc. | System state driven display for medical procedures |
US8806359B2 (en) | 2006-09-06 | 2014-08-12 | Stereotaxis, Inc. | Workflow driven display for medical procedures |
US8799792B2 (en) | 2006-09-06 | 2014-08-05 | Stereotaxis, Inc. | Workflow driven method of performing multi-step medical procedures |
US8244824B2 (en) | 2006-09-06 | 2012-08-14 | Stereotaxis, Inc. | Coordinated control for multiple computer-controlled medical systems |
US20080065061A1 (en) * | 2006-09-08 | 2008-03-13 | Viswanathan Raju R | Impedance-Based Cardiac Therapy Planning Method with a Remote Surgical Navigation System |
US8273081B2 (en) | 2006-09-08 | 2012-09-25 | Stereotaxis, Inc. | Impedance-based cardiac therapy planning method with a remote surgical navigation system |
US20080064969A1 (en) * | 2006-09-11 | 2008-03-13 | Nathan Kastelein | Automated Mapping of Anatomical Features of Heart Chambers |
US20080097200A1 (en) * | 2006-10-20 | 2008-04-24 | Blume Walter M | Location and Display of Occluded Portions of Vessels on 3-D Angiographic Images |
US8135185B2 (en) | 2006-10-20 | 2012-03-13 | Stereotaxis, Inc. | Location and display of occluded portions of vessels on 3-D angiographic images |
US20080132910A1 (en) * | 2006-11-07 | 2008-06-05 | Carlo Pappone | Control for a Remote Navigation System |
US20080200913A1 (en) * | 2007-02-07 | 2008-08-21 | Viswanathan Raju R | Single Catheter Navigation for Diagnosis and Treatment of Arrhythmias |
US20080195171A1 (en) * | 2007-02-13 | 2008-08-14 | Sharma Virender K | Method and Apparatus for Electrical Stimulation of the Pancreatico-Biliary System |
US9037244B2 (en) | 2007-02-13 | 2015-05-19 | Virender K. Sharma | Method and apparatus for electrical stimulation of the pancreatico-biliary system |
US20080208912A1 (en) * | 2007-02-26 | 2008-08-28 | Garibaldi Jeffrey M | System and method for providing contextually relevant medical information |
US20080228068A1 (en) * | 2007-03-13 | 2008-09-18 | Viswanathan Raju R | Automated Surgical Navigation with Electro-Anatomical and Pre-Operative Image Data |
US20080228065A1 (en) * | 2007-03-13 | 2008-09-18 | Viswanathan Raju R | System and Method for Registration of Localization and Imaging Systems for Navigational Control of Medical Devices |
US20080287909A1 (en) * | 2007-05-17 | 2008-11-20 | Viswanathan Raju R | Method and apparatus for intra-chamber needle injection treatment |
US20080294232A1 (en) * | 2007-05-22 | 2008-11-27 | Viswanathan Raju R | Magnetic cell delivery |
US20080292901A1 (en) * | 2007-05-24 | 2008-11-27 | Hon Hai Precision Industry Co., Ltd. | Magnesium alloy and thin workpiece made of the same |
US20080312673A1 (en) * | 2007-06-05 | 2008-12-18 | Viswanathan Raju R | Method and apparatus for CTO crossing |
US8024024B2 (en) | 2007-06-27 | 2011-09-20 | Stereotaxis, Inc. | Remote control of medical devices using real time location data |
US20090177037A1 (en) * | 2007-06-27 | 2009-07-09 | Viswanathan Raju R | Remote control of medical devices using real time location data |
US20090012821A1 (en) * | 2007-07-06 | 2009-01-08 | Guy Besson | Management of live remote medical display |
US9111016B2 (en) | 2007-07-06 | 2015-08-18 | Stereotaxis, Inc. | Management of live remote medical display |
US20090082722A1 (en) * | 2007-08-21 | 2009-03-26 | Munger Gareth T | Remote navigation advancer devices and methods of use |
US20090105579A1 (en) * | 2007-10-19 | 2009-04-23 | Garibaldi Jeffrey M | Method and apparatus for remotely controlled navigation using diagnostically enhanced intra-operative three-dimensional image data |
US8231618B2 (en) | 2007-11-05 | 2012-07-31 | Stereotaxis, Inc. | Magnetically guided energy delivery apparatus |
US20090131798A1 (en) * | 2007-11-19 | 2009-05-21 | Minar Christopher D | Method and apparatus for intravascular imaging and occlusion crossing |
US20090131927A1 (en) * | 2007-11-20 | 2009-05-21 | Nathan Kastelein | Method and apparatus for remote detection of rf ablation |
US20150257705A1 (en) * | 2008-08-06 | 2015-09-17 | Carag Ag | Catheter for Measuring the Blood Flow of a Body Tissue |
US20100069733A1 (en) * | 2008-09-05 | 2010-03-18 | Nathan Kastelein | Electrophysiology catheter with electrode loop |
US10376694B2 (en) | 2008-10-09 | 2019-08-13 | Virender K. Sharma | Method and apparatus for stimulating the vascular system |
US11517749B2 (en) | 2008-10-09 | 2022-12-06 | Virender K. Sharma | Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage |
US10603489B2 (en) | 2008-10-09 | 2020-03-31 | Virender K. Sharma | Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage |
US20100298845A1 (en) * | 2009-05-25 | 2010-11-25 | Kidd Brian L | Remote manipulator device |
US20110130718A1 (en) * | 2009-05-25 | 2011-06-02 | Kidd Brian L | Remote Manipulator Device |
US10537713B2 (en) | 2009-05-25 | 2020-01-21 | Stereotaxis, Inc. | Remote manipulator device |
US20110046618A1 (en) * | 2009-08-04 | 2011-02-24 | Minar Christopher D | Methods and systems for treating occluded blood vessels and other body cannula |
US10159734B2 (en) | 2009-11-02 | 2018-12-25 | Pulse Therapeutics, Inc. | Magnetic particle control and visualization |
US10813997B2 (en) | 2009-11-02 | 2020-10-27 | Pulse Therapeutics, Inc. | Devices for controlling magnetic nanoparticles to treat fluid obstructions |
US11612655B2 (en) | 2009-11-02 | 2023-03-28 | Pulse Therapeutics, Inc. | Magnetic particle control and visualization |
US9339664B2 (en) | 2009-11-02 | 2016-05-17 | Pulse Therapetics, Inc. | Control of magnetic rotors to treat therapeutic targets |
US9345498B2 (en) | 2009-11-02 | 2016-05-24 | Pulse Therapeutics, Inc. | Methods of controlling magnetic nanoparticles to improve vascular flow |
US8715150B2 (en) | 2009-11-02 | 2014-05-06 | Pulse Therapeutics, Inc. | Devices for controlling magnetic nanoparticles to treat fluid obstructions |
US11000589B2 (en) | 2009-11-02 | 2021-05-11 | Pulse Therapeutics, Inc. | Magnetic particle control and visualization |
US10029008B2 (en) | 2009-11-02 | 2018-07-24 | Pulse Therapeutics, Inc. | Therapeutic magnetic control systems and contrast agents |
US8529428B2 (en) | 2009-11-02 | 2013-09-10 | Pulse Therapeutics, Inc. | Methods of controlling magnetic nanoparticles to improve vascular flow |
US8313422B2 (en) | 2009-11-02 | 2012-11-20 | Pulse Therapeutics, Inc. | Magnetic-based methods for treating vessel obstructions |
US8926491B2 (en) | 2009-11-02 | 2015-01-06 | Pulse Therapeutics, Inc. | Controlling magnetic nanoparticles to increase vascular flow |
US8308628B2 (en) | 2009-11-02 | 2012-11-13 | Pulse Therapeutics, Inc. | Magnetic-based systems for treating occluded vessels |
US8961435B2 (en) * | 2011-08-18 | 2015-02-24 | Radius Medical LLC | Coaxial guidewire for small vessel access |
US20130046203A1 (en) * | 2011-08-18 | 2013-02-21 | Richard M. DeMello | Coaxial guidewire for small vessel access |
US10646241B2 (en) | 2012-05-15 | 2020-05-12 | Pulse Therapeutics, Inc. | Detection of fluidic current generated by rotating magnetic particles |
US9883878B2 (en) | 2012-05-15 | 2018-02-06 | Pulse Therapeutics, Inc. | Magnetic-based systems and methods for manipulation of magnetic particles |
US10722139B2 (en) | 2015-02-16 | 2020-07-28 | Biosense Webster (Israel) Ltd. | Navigation of an angioplasty guidewire |
US11020017B2 (en) | 2015-02-16 | 2021-06-01 | Biosense Webster (Israel) Ltd. | Angioplasty guidewire |
EP3056161A1 (en) | 2015-02-16 | 2016-08-17 | Biosense Webster (Israel) Ltd. | Angioplasty guidewire |
US10349817B2 (en) * | 2017-01-12 | 2019-07-16 | Endostart S.r.l. | Method for introducing colonoscope using endoscopic guide |
US11278189B2 (en) | 2017-01-12 | 2022-03-22 | Endostart S.r.l. | Endoscopic guide including anchoring head that accommodates a magnetic or ferromagnetic agent |
US10252030B2 (en) | 2017-01-17 | 2019-04-09 | Cook Medical Technologies Llc | Handheld magnetic gun for guide wire manipulation |
US11918315B2 (en) | 2018-05-03 | 2024-03-05 | Pulse Therapeutics, Inc. | Determination of structure and traversal of occlusions using magnetic particles |
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