US20100049293A1 - Controlled deployable medical device and method of making the same - Google Patents
Controlled deployable medical device and method of making the same Download PDFInfo
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- US20100049293A1 US20100049293A1 US12/478,245 US47824509A US2010049293A1 US 20100049293 A1 US20100049293 A1 US 20100049293A1 US 47824509 A US47824509 A US 47824509A US 2010049293 A1 US2010049293 A1 US 2010049293A1
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- stent
- graft
- end portion
- torsional member
- distal end
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/954—Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
- A61F2/97—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve the outer sleeve being splittable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/89—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9505—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9505—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
- A61F2002/9511—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument the retaining means being filaments or wires
Definitions
- the invention relates generally to devices that are retained inside a body passage and in one particular application to vascular devices used in repairing arterial dilations, e.g., aneurysms. More particularly, the invention is directed toward devices that can be adjusted during deployment, thereby allowing at least one of a longitudinal or radial re-positioning of the device.
- the invention will be discussed generally with respect to deployment of a bifurcated stent graft into the abdominal aorta but is not so limited and may apply to device deployment into other body lumens.
- a stent graft When delivering a stent graft by intraluminal or endovascular methods, it is important to know the precise location of the device in the vasculature. Controlling this precise location is particularly important when the device is intended to be deployed in close proximity to branch vessels or adjacent to weakened portions of the aortic wall.
- Typical stent grafts used to repair an aortic aneurysm incorporate a proximal (i.e. portion of the stent graft closest to the heart) anchoring system intended to limit longitudinal displacement of the stent graft. Often this anchoring system must be precisely placed to avoid occlusion of a branch vessel or to avoid placement within a compromised and damaged portion of the aortic wall.
- An improved delivery system for such stent grafts would include a means for allowing precise longitudinal and rotational placement of the stent graft and anchoring system. The precise position of the stent graft and anchoring system would be adjusted and visualized prior to full deployment of the device. Ideally the delivery system would allow the device to be repositioned if the prior deployment position was undesirable.
- the present invention is directed to a controlled deployable medical device and method of making the same that substantially obviates one or more of the problems due to limitations and disadvantages of the related art.
- An embodiment of the present invention provides an apparatus, comprising a catheter having a proximal end portion and distal end portion.
- a hub can be arranged on a distal end portion of the catheter.
- a stent member is arranged on the proximal end portion of the catheter, the stent member has an inner surface and an outer surface.
- the stent can be configured in any suitable manner.
- the stent is configured from multiple turns of an undulating element.
- Such a stent member can have substantially in-phase undulations.
- a graft member can be arranged about the stent member.
- an element can be connected to a torsional member, wherein the torsional member is capable of retracting a portion of the element and thereby radially compressing at least a portion of the stent.
- the present invention provides an apparatus substantially as described above, further comprising a tube having a proximal end portion and distal end portion arranged on at least a portion of the substantially tubular shaped stent member, wherein at least a portion of the torsional member extends within a portion of the tube.
- FIG. 1A is a medical apparatus according to an aspect of the invention, having an external torsional member.
- FIG. 1B is an enlarged simplified view of the medical apparatus of FIG. 1A according to an aspect of the invention.
- FIG. 1C is a medical apparatus according to an aspect of the invention, having an internal torsional member.
- FIGS. 2A and 2B are a medical apparatus according to an aspect of the invention, having flexible straps connected to a torsional member.
- FIG. 3A is a medical apparatus according to an aspect of the invention, having an external torsional member connected to a flexible sleeve with a rip cord.
- FIG. 3B is a medical apparatus according to an aspect of the invention, having an internal torsional member connected to a flexible constraining sleeve with a parting line.
- the invention relates generally to a novel medical apparatus that includes a device capable of being retained inside a body passage and in one particular application to vascular devices. More particularly, the invention is directed toward devices that can be adjusted during deployment, thereby allowing at least one of a longitudinal or radial re-positioning.
- distal denotes a position furthest from the heart
- proximal denotes a position closest to the heart.
- the medical apparatus includes a catheter assembly having a proximal end portion and distal end portion.
- a hub can be optionally arranged on a distal end portion of the catheter assembly.
- a stent is arranged on a proximal end portion of the catheter.
- a graft member can be arranged about at least a portion of the stent.
- the stent may be self-expandable, balloon-expandable or a combination of self-expandable and balloon-expandable.
- the stents can be used to fix the medical apparatus inside a portion of a patient's anatomy.
- the stent can be preferably constructed from materials that are flexible and strong.
- the stent can be formed from degradable bioabsorbable materials, biodigestible materials, polymeric materials, metallic materials and combinations thereof.
- these materials may be reinforced and/or coated with other materials, such as polymeric materials and the like.
- the coating may be chosen to reduce acidic or basic effects of the gastrointestinal tract, e.g., with a thermoplastic coating such as ePTFE and the like.
- the stents can be fabricated according to the methods and materials as generally disclosed in, for example, U.S. Pat. No. 6,042,605 issued to Martin, et al., U.S. Pat. No. 6,361,637 issued to Martin, et al. and U.S. Pat. No. 6,520,986 issued to Martin, et al.
- stents can have various configurations as known in the art and can be fabricated, for example, from cut tubes, wound wires (or ribbons), flat patterned sheets rolled into a tubular form, combinations thereof, and the like.
- Stents can be formed from metallic, polymeric or natural materials and can comprise conventional medical grade materials such as nylon, polyacrylamide, polycarbonate, polyethylene, polyformaldehyde, polymethylmethacrylate, polypropylene, polytetrafluoroethylene, polytrifluorochlorethylene, polyvinylchloride, polyurethane, elastomeric organosilicon polymers; metals such as stainless steels, cobalt-chromium alloys and nitinol and biologically derived materials such as bovine arteries/veins, pericardium and collagen.
- conventional medical grade materials such as nylon, polyacrylamide, polycarbonate, polyethylene, polyformaldehyde, polymethylmethacrylate, polypropylene, polytetrafluoroethylene, polytrifluorochlorethylene, polyvinylchloride, polyurethane, elastomeric organosilicon polymers
- metals such as stainless steels, cobalt-chromium alloys and nitinol
- Stents can also comprise bioresorbable materials such as poly(amino acids), poly(anhydrides), poly(caprolactones), poly(lactic/glycolic acid) polymers, poly(hydroxybutyrates) and poly(orthoesters).
- bioresorbable materials such as poly(amino acids), poly(anhydrides), poly(caprolactones), poly(lactic/glycolic acid) polymers, poly(hydroxybutyrates) and poly(orthoesters).
- the stents can be formed into a variety of different geometric configurations having constant and/or varied thickness as known in the art.
- the geometric configurations may include many conventional stent configurations such as a helically wrapped stent, z-shape stent, tapered stent, coil stent, combinations thereof, and the like.
- the stents can be formed in a variety of patterns, such as, a helix pattern, ring pattern, combinations thereof, and the like.
- Grafts can have various configurations as known in the art and can be fabricated, for example, from tubes, sheets or films formed into tubular shapes, woven or knitted fibers or ribbons or combinations thereof. Graft materials can include, for example, conventional medical grade materials such as nylon, polyester, polyethylene, polypropylene, polytetrafluoroethylene, polyvinylchloride, polyurethane and elastomeric organosilicone polymers.
- Stents can be used alone or in combination with graft materials. Stents can be configured on the external or internal surface of a graft or may be incorporated into the internal wall structure of a graft. Stent or stent grafts can be delivered endoluminally by various catheter based procedures known in the art. For example self-expanding endoluminal devices can be compressed and maintained in a constrained state by an external sheath. The sheath can be folded to form a tube positioned external to the compressed device. The sheath edges can be sewn together with a deployment cord that forms a “chain stitch”.
- Constraining sheaths and deployment cord stitching can be configured to release a self-expanding device in several ways.
- a constraining sheath may release a device starting from the proximal device end, terminating at the distal device end. In other configurations the device may be released starting from the distal end.
- Self expanding devices may also be released from the device center as the sheath disrupts toward the device distal and proximal ends.
- the catheter and hub assemblies can comprise conventional medical grade materials such as nylon, polyacrylamide, polycarbonate, polyethylene, polyformaldehyde, polymethylmethacrylate, polypropylene, polytetrafluoroethylene, polytrifluorochlorethylene, polyether block amide or thermoplastic copolyether, polyvinylchloride, polyurethane, elastomeric organosilicone polymers, and metals such as stainless steels and nitinol.
- conventional medical grade materials such as nylon, polyacrylamide, polycarbonate, polyethylene, polyformaldehyde, polymethylmethacrylate, polypropylene, polytetrafluoroethylene, polytrifluorochlorethylene, polyether block amide or thermoplastic copolyether, polyvinylchloride, polyurethane, elastomeric organosilicone polymers, and metals such as stainless steels and nitinol.
- FIG. 1A is a medical apparatus according to an embodiment of the invention.
- FIG. 1B is an enlarged simplified view of a portion of the medical apparatus shown in FIG. 1A .
- the medical apparatus 100 A includes catheter assembly 102 , stent 104 arranged on the proximal end portion of the catheter assembly 102 .
- the stent 104 has an inner surface, an outer surface, and is configured from multiple turns of an undulating element 105 .
- the undulating element 105 can be configured, for example, in a ring or helical pattern.
- the stent 104 has a proximal end portion 106 and distal end portion 108 .
- the distal end portion 108 is formed into a branch having a first leg 110 and a second leg 112 .
- a graft member 114 is arranged about the stent 104 .
- the stent 104 and graft member 114 are constrained into a compacted delivery state by a first sheath 116 and second sheath 118 .
- first sheath 116 has been released allowing at least a portion of the stent 104 to expand as shown.
- the second sheath 118 is coupling the second leg 112 to the catheter assembly 102 as shown.
- a torsional member 120 extends from a proximal end portion to a distal end portion of the catheter assembly 102 .
- the torsional member 120 is positioned adjacent the outer surface of the stent 104 and graft 114 .
- the torsional member 120 is attached to the catheter assembly 102 and not attached to the stent 104 or graft 114 .
- a movable element 122 having a first end 124 and second end 126 surrounds the stent 104 and graft member 114 .
- the first end 124 and second end 126 of the movable element 122 extend out a distal end portion of the torsional member 120 .
- the movable element 122 is threaded through the tube from a distal end to a proximal end and is looped around the proximal end portion 106 of the stent 104 and graft member 114 .
- the torsional member 120 can be rotated in the direction shown by arrow 130 , tensioning the movable element 122 thereby causing at least a portion of the stent/graft to radial compress in the direction indicated by arrows 128 .
- the torsional member 120 can be configured with a side-wall aperture 132 through which the two ends 124 , 126 of the movable element 122 can be routed.
- the torsional member 120 can be rotated by turning the distal end of the tube 120 .
- the torsional member 120 can be rotated in the opposite direction (of that shown by arrow 130 ) to allow the stent/graft to expand in the direction opposite of arrows 128 .
- the stent/graft can be compressed to allow rotational or longitudinal displacements within a vessel. When the desired placement is verified, the stent/graft can be allowed to expand and engage the vessel wall. Repeated compressions and expansions of the stent/graft can be utilized as desired.
- the stent/graft can also be gradually compressed or allowed to gradually expand by varying the amount of twist imparted to the torsional member 120 . After final placement of the stent/graft, tension can be applied to one of the ends 124 , 126 of the moveable element 122 to release and withdraw the movable element.
- FIG. 1C is a medical apparatus according to a further embodiment of the invention, having a torsional member 120 positioned internal to the stent/graft.
- the medical apparatus is generally depicted as reference numeral 10 B.
- the medical apparatus of FIG. 1C is similar to the medical apparatus as shown in FIGS. 1A and 1B .
- the medical apparatus includes a stent 104 and/or a graft 114 arranged on the proximal end portion of the catheter assembly.
- a torsional member 120 extends from a proximal end portion to a distal end portion of the catheter assembly.
- the torsional member 120 is positioned internal to the stent 104 and graft 114 .
- the torsional member 120 is attached to the catheter assembly and not attached to the stent 104 or graft 114 .
- a movable element 122 having a first end 124 and second end 126 is looped through and around the stent 104 and graft member 114 .
- the first end 124 and second end 126 of the movable element 122 extend out a distal end portion of the torsional member 120 .
- the movable element 122 is threaded through the tube from a distal end to a proximal end and is looped around the proximal end portion of the stent 104 and graft member 114 .
- the torsional member 120 can be rotated in the direction shown by arrow 130 , tensioning the movable element 122 thereby causing at least a portion of the stent/graft to radial compress in the direction indicated by arrows 128 .
- the torsional member 120 can be configured with a side-wall aperture 132 through which the two ends 124 , 126 of the movable element 122 can be routed.
- the torsional member 120 can be rotated by turning the distal end of the torsional member 120 .
- the torsional member 120 can be rotated in the opposite direction (of that shown by arrow 130 ) to allow the stent/graft to expand in the direction opposite of arrows 128 .
- the stent/graft can be compressed to allow rotational or longitudinal displacements within a vessel. When the desired placement is verified, the stent/graft can be allowed to expand and engage the vessel wall. Repeated compressions and expansions of the stent/graft can be utilized as desired.
- the stent/graft can also be gradually compressed or allowed to gradually expand by varying the amount of twist imparted to the torsional member 120 . After final placement of the stent/graft, tension can be applied to one of the moveable ends 124 , 126 of the moveable element 122 to release and withdraw the movable element.
- FIGS. 2A and 2B are partial views of the proximal end of a medical apparatus according to a further embodiment of the invention, having releasable straps that can radial compress a stent/graft.
- the medical apparatus is generally depicted as reference numeral 200 .
- the medical apparatus of FIGS. 2A and 2B is similar to the medical apparatus as shown in FIGS. 1A through 1C with a stent/graft not shown for clarity.
- FIG. 2A Shown in FIG. 2A is a partial cross-section of a distal end of a catheter system 200 having an outer tube 202 . Contained within the outer tube 202 are a first inner tube 204 and a torsional member 206 . Attached to the torsional member is at least one flexible strap 208 . The flexible strap 208 surrounds a distal portion of a stent/graft (not shown). When the torsional member 206 is rotated as depicted by arrow 210 the strap 208 is further wound around the torsional member 206 , thereby “drawing in” the strap which will in turn, compress a surrounded stent/graft.
- the degree of stent/graft compression can be controlled by varying the amount of twist imparted to the torsional member.
- a first end 212 of a flexible strap 208 can be affixed to the torsional member 206 .
- the second end 214 of the strap 208 can be wrapped around the torsional member.
- the torsional member can be rotated in a direction opposite that shown by arrow 210 . This opposite rotation will allow the stent/graft to fully expand. Further opposite rotation of the torsional member will cause the strap end 214 to “un-wind” from the torsional member.
- the torsional member can then be withdrawn in a distal direction, pulling the strap with attached end 212 into the first inner tube.
- the first inner tube and the torsional member can be withdrawn together or all three members ( 204 , 206 , 208 ) can be withdrawn together.
- FIG. 2B Shown in FIG. 2B is a non cross-sectional perspective view of the distal end of the catheter system shown in FIG. 2A .
- the flexible straps 208 can be fabricated from various bio-compatible materials as commonly known in the art.
- FIGS. 3A and 3B are partial perspective views of a medical apparatus according to a further embodiment of the invention.
- the medical apparatus is generally depicted as reference numeral 300 A or 300 B.
- the medical apparatus 300 A and B includes catheter assembly 102 , stent 104 arranged on the proximal end portion of the catheter assembly 102 .
- the stent 104 has an inner surface, an outer surface, and is configured from multiple turns of an undulating element 105 .
- the undulating element 105 can be configured, for example, in a ring or helical pattern.
- the stent 104 has a proximal end portion 106 and distal end portion 108 .
- the distal end portion 108 is formed into a branch having a first leg 110 and a second leg 112 .
- a graft member 114 is arranged about the stent 104 .
- the stent 104 and graft member 114 are constrained into a compacted delivery state by a first sheath 116 and second sheath 118 .
- the first sheath 116 has been released allowing at least a portion of the stent 104 to expand as shown.
- the second sheath 118 is coupling the second leg 112 to the catheter assembly 102 as shown.
- FIG. 3A Shown in FIG. 3A is a flexible constraining sleeve 302 , surrounding a proximal portion of the stent/graft.
- a torsional member 120 extends from a proximal end portion to a distal end portion of the catheter assembly 102 .
- the torsional member 120 is positioned adjacent the outer surface of the stent 104 and graft 114 .
- the torsional member 120 is attached to the catheter assembly 102 and not attached to the stent 104 or graft 114 .
- the flexible sleeve 302 is attached to the torsional member 120 so that when the torsional member 120 is rotated, the flexible sleeve is compressed which in turn compresses the stent/graft.
- the flexible sleeve 302 is shown having a parting or rip cord 304 .
- the rip cord 304 can be in the form of a thread or wire that is contained within a secondary tube 306 .
- the secondary tube 306 can exit the distal end of the catheter assembly 102 with the rip cord exiting the distal end of the secondary tube.
- the distal end of the rip cord can be tensioned, thereby ripping or separating the flexible sleeve 302 . Since the flexible sleeve is still attached to the torsional member 120 , the flexible sleeve 302 can then be withdrawn along with the catheter assembly 102 .
- FIG. 3B Shown in FIG. 3B is a flexible constraining sleeve 302 , surrounding a proximal portion of the stent/graft.
- a torsional member 310 extends from a proximal end portion to a distal end portion of the catheter assembly 102 .
- the torsional member 310 is positioned adjacent the outer surface of the stent 104 and graft 114 .
- the torsional member 310 is attached to the catheter assembly 102 and not attached to the stent 104 or graft 114 .
- the flexible sleeve 302 is attached to the torsional member 310 so that when the torsional member 310 is rotated, the flexible sleeve is compressed which in turn compresses the stent/graft.
- the flexible sleeve 302 is shown having a parting line 312 . Shown is a stitched parting line 312 similar to those parting lines incorporated into the first 116 and second 118 sheaths.
- the release of the stitched parting line 312 can be activated by a release cord 314 .
- the release cord 314 can be in the form of a thread or wire and can be contained within a secondary tube (not shown) or be contained within a catheter system lumen.
- the release cord 314 can exit the distal end of the catheter assembly 102 .
- the distal end of the release cord 314 can be tensioned, thereby un-stitching or separating the flexible sleeve 302 . Since the flexible sleeve is still attached to the torsional member 310 , the flexible sleeve 302 can then be withdrawn along with the catheter assembly 102 .
Abstract
Controlled deployable medical devices that are retained inside a body passage and in one particular application to vascular devices used in repairing arterial dilations, e.g., aneurysms. Such devices can be adjusted during deployment, thereby allowing at least one of a longitudinal or radial re-positioning, resulting in precise alignment of the device to an implant target site.
Description
- This application claims priority to provisional application U.S. Ser. No. 61/058,770, filed Jun. 4, 2008.
- 1. Field of the Invention
- The invention relates generally to devices that are retained inside a body passage and in one particular application to vascular devices used in repairing arterial dilations, e.g., aneurysms. More particularly, the invention is directed toward devices that can be adjusted during deployment, thereby allowing at least one of a longitudinal or radial re-positioning of the device.
- 2. Discussion of the Related Art
- The invention will be discussed generally with respect to deployment of a bifurcated stent graft into the abdominal aorta but is not so limited and may apply to device deployment into other body lumens. When delivering a stent graft by intraluminal or endovascular methods, it is important to know the precise location of the device in the vasculature. Controlling this precise location is particularly important when the device is intended to be deployed in close proximity to branch vessels or adjacent to weakened portions of the aortic wall. Typical stent grafts used to repair an aortic aneurysm incorporate a proximal (i.e. portion of the stent graft closest to the heart) anchoring system intended to limit longitudinal displacement of the stent graft. Often this anchoring system must be precisely placed to avoid occlusion of a branch vessel or to avoid placement within a compromised and damaged portion of the aortic wall.
- An improved delivery system for such stent grafts would include a means for allowing precise longitudinal and rotational placement of the stent graft and anchoring system. The precise position of the stent graft and anchoring system would be adjusted and visualized prior to full deployment of the device. Ideally the delivery system would allow the device to be repositioned if the prior deployment position was undesirable.
- The present invention is directed to a controlled deployable medical device and method of making the same that substantially obviates one or more of the problems due to limitations and disadvantages of the related art.
- An embodiment of the present invention provides an apparatus, comprising a catheter having a proximal end portion and distal end portion. A hub can be arranged on a distal end portion of the catheter. A stent member is arranged on the proximal end portion of the catheter, the stent member has an inner surface and an outer surface. The stent can be configured in any suitable manner. In an embodiment of the invention, the stent is configured from multiple turns of an undulating element. Such a stent member can have substantially in-phase undulations. A graft member can be arranged about the stent member. Moreover, an element can be connected to a torsional member, wherein the torsional member is capable of retracting a portion of the element and thereby radially compressing at least a portion of the stent.
- In another embodiment, the present invention provides an apparatus substantially as described above, further comprising a tube having a proximal end portion and distal end portion arranged on at least a portion of the substantially tubular shaped stent member, wherein at least a portion of the torsional member extends within a portion of the tube.
- The accompanying drawings are included to provide a further understanding of the invention and illustrate certain aspects of the invention.
- In the drawings:
-
FIG. 1A is a medical apparatus according to an aspect of the invention, having an external torsional member. -
FIG. 1B is an enlarged simplified view of the medical apparatus ofFIG. 1A according to an aspect of the invention. -
FIG. 1C is a medical apparatus according to an aspect of the invention, having an internal torsional member. -
FIGS. 2A and 2B are a medical apparatus according to an aspect of the invention, having flexible straps connected to a torsional member. -
FIG. 3A is a medical apparatus according to an aspect of the invention, having an external torsional member connected to a flexible sleeve with a rip cord. -
FIG. 3B is a medical apparatus according to an aspect of the invention, having an internal torsional member connected to a flexible constraining sleeve with a parting line. - The invention relates generally to a novel medical apparatus that includes a device capable of being retained inside a body passage and in one particular application to vascular devices. More particularly, the invention is directed toward devices that can be adjusted during deployment, thereby allowing at least one of a longitudinal or radial re-positioning. The term distal as used herein denotes a position furthest from the heart, while the term proximal denotes a position closest to the heart.
- In an embodiment of the invention, the medical apparatus includes a catheter assembly having a proximal end portion and distal end portion. A hub can be optionally arranged on a distal end portion of the catheter assembly. A stent is arranged on a proximal end portion of the catheter. A graft member can be arranged about at least a portion of the stent. The stent may be self-expandable, balloon-expandable or a combination of self-expandable and balloon-expandable.
- In some embodiments, the stents can be used to fix the medical apparatus inside a portion of a patient's anatomy. The stent can be preferably constructed from materials that are flexible and strong. The stent can be formed from degradable bioabsorbable materials, biodigestible materials, polymeric materials, metallic materials and combinations thereof. In addition, these materials may be reinforced and/or coated with other materials, such as polymeric materials and the like. The coating may be chosen to reduce acidic or basic effects of the gastrointestinal tract, e.g., with a thermoplastic coating such as ePTFE and the like.
- More specifically, the stents can be fabricated according to the methods and materials as generally disclosed in, for example, U.S. Pat. No. 6,042,605 issued to Martin, et al., U.S. Pat. No. 6,361,637 issued to Martin, et al. and U.S. Pat. No. 6,520,986 issued to Martin, et al. For example, stents can have various configurations as known in the art and can be fabricated, for example, from cut tubes, wound wires (or ribbons), flat patterned sheets rolled into a tubular form, combinations thereof, and the like. Stents can be formed from metallic, polymeric or natural materials and can comprise conventional medical grade materials such as nylon, polyacrylamide, polycarbonate, polyethylene, polyformaldehyde, polymethylmethacrylate, polypropylene, polytetrafluoroethylene, polytrifluorochlorethylene, polyvinylchloride, polyurethane, elastomeric organosilicon polymers; metals such as stainless steels, cobalt-chromium alloys and nitinol and biologically derived materials such as bovine arteries/veins, pericardium and collagen. Stents can also comprise bioresorbable materials such as poly(amino acids), poly(anhydrides), poly(caprolactones), poly(lactic/glycolic acid) polymers, poly(hydroxybutyrates) and poly(orthoesters).
- The stents can be formed into a variety of different geometric configurations having constant and/or varied thickness as known in the art. The geometric configurations may include many conventional stent configurations such as a helically wrapped stent, z-shape stent, tapered stent, coil stent, combinations thereof, and the like. The stents can be formed in a variety of patterns, such as, a helix pattern, ring pattern, combinations thereof, and the like.
- Grafts can have various configurations as known in the art and can be fabricated, for example, from tubes, sheets or films formed into tubular shapes, woven or knitted fibers or ribbons or combinations thereof. Graft materials can include, for example, conventional medical grade materials such as nylon, polyester, polyethylene, polypropylene, polytetrafluoroethylene, polyvinylchloride, polyurethane and elastomeric organosilicone polymers.
- Stents can be used alone or in combination with graft materials. Stents can be configured on the external or internal surface of a graft or may be incorporated into the internal wall structure of a graft. Stent or stent grafts can be delivered endoluminally by various catheter based procedures known in the art. For example self-expanding endoluminal devices can be compressed and maintained in a constrained state by an external sheath. The sheath can be folded to form a tube positioned external to the compressed device. The sheath edges can be sewn together with a deployment cord that forms a “chain stitch”. To release and deploy the constrained device, one end of the deployment cord can be pulled to disrupt the chain stitch, allowing the sheath edges to separate and release the constrained device. Constraining sheaths and deployment cord stitching can be configured to release a self-expanding device in several ways. For example a constraining sheath may release a device starting from the proximal device end, terminating at the distal device end. In other configurations the device may be released starting from the distal end. Self expanding devices may also be released from the device center as the sheath disrupts toward the device distal and proximal ends.
- Details relating to constraining sheath materials, sheath methods of manufacture and stent graft compression techniques can be found in, for example, U.S. Pat. No. 6,352,561 issued to Leopold, et al., and U.S. Pat. No. 6,551,350 issued to Thornton, et al.
- The catheter and hub assemblies can comprise conventional medical grade materials such as nylon, polyacrylamide, polycarbonate, polyethylene, polyformaldehyde, polymethylmethacrylate, polypropylene, polytetrafluoroethylene, polytrifluorochlorethylene, polyether block amide or thermoplastic copolyether, polyvinylchloride, polyurethane, elastomeric organosilicone polymers, and metals such as stainless steels and nitinol.
- Turning to the figures,
FIG. 1A is a medical apparatus according to an embodiment of the invention.FIG. 1B is an enlarged simplified view of a portion of the medical apparatus shown inFIG. 1A . - Referring to
FIGS. 1A and 1B , the medical apparatus is generally depicted asreference numeral 100A. Themedical apparatus 100A includescatheter assembly 102,stent 104 arranged on the proximal end portion of thecatheter assembly 102. Thestent 104 has an inner surface, an outer surface, and is configured from multiple turns of anundulating element 105. The undulatingelement 105 can be configured, for example, in a ring or helical pattern. - The
stent 104 has aproximal end portion 106 anddistal end portion 108. Thedistal end portion 108 is formed into a branch having afirst leg 110 and asecond leg 112. - A
graft member 114 is arranged about thestent 104. - In an embodiment of the invention, the
stent 104 andgraft member 114 are constrained into a compacted delivery state by afirst sheath 116 andsecond sheath 118. As shown inFIG. 1A , thefirst sheath 116 has been released allowing at least a portion of thestent 104 to expand as shown. Thesecond sheath 118 is coupling thesecond leg 112 to thecatheter assembly 102 as shown. - A
torsional member 120 extends from a proximal end portion to a distal end portion of thecatheter assembly 102. In the figure, thetorsional member 120 is positioned adjacent the outer surface of thestent 104 andgraft 114. Thetorsional member 120 is attached to thecatheter assembly 102 and not attached to thestent 104 orgraft 114. Amovable element 122 having afirst end 124 andsecond end 126 surrounds thestent 104 andgraft member 114. Thefirst end 124 andsecond end 126 of themovable element 122 extend out a distal end portion of thetorsional member 120. For example, themovable element 122 is threaded through the tube from a distal end to a proximal end and is looped around theproximal end portion 106 of thestent 104 andgraft member 114. - As shown in
FIG. 1B , thetorsional member 120 can be rotated in the direction shown byarrow 130, tensioning themovable element 122 thereby causing at least a portion of the stent/graft to radial compress in the direction indicated byarrows 128. Thetorsional member 120 can be configured with a side-wall aperture 132 through which the two ends 124, 126 of themovable element 122 can be routed. Thetorsional member 120 can be rotated by turning the distal end of thetube 120. Thetorsional member 120 can be rotated in the opposite direction (of that shown by arrow 130) to allow the stent/graft to expand in the direction opposite ofarrows 128. The stent/graft can be compressed to allow rotational or longitudinal displacements within a vessel. When the desired placement is verified, the stent/graft can be allowed to expand and engage the vessel wall. Repeated compressions and expansions of the stent/graft can be utilized as desired. The stent/graft can also be gradually compressed or allowed to gradually expand by varying the amount of twist imparted to thetorsional member 120. After final placement of the stent/graft, tension can be applied to one of theends moveable element 122 to release and withdraw the movable element. -
FIG. 1C is a medical apparatus according to a further embodiment of the invention, having atorsional member 120 positioned internal to the stent/graft. - Referring to
FIG. 1C , the medical apparatus is generally depicted as reference numeral 10B. The medical apparatus ofFIG. 1C is similar to the medical apparatus as shown inFIGS. 1A and 1B . The medical apparatus includes astent 104 and/or agraft 114 arranged on the proximal end portion of the catheter assembly. - A
torsional member 120 extends from a proximal end portion to a distal end portion of the catheter assembly. Thetorsional member 120 is positioned internal to thestent 104 andgraft 114. Thetorsional member 120 is attached to the catheter assembly and not attached to thestent 104 orgraft 114. Amovable element 122 having afirst end 124 andsecond end 126 is looped through and around thestent 104 andgraft member 114. Thefirst end 124 andsecond end 126 of themovable element 122 extend out a distal end portion of thetorsional member 120. For example, themovable element 122 is threaded through the tube from a distal end to a proximal end and is looped around the proximal end portion of thestent 104 andgraft member 114. As shown inFIG. 1C , thetorsional member 120 can be rotated in the direction shown byarrow 130, tensioning themovable element 122 thereby causing at least a portion of the stent/graft to radial compress in the direction indicated byarrows 128. Thetorsional member 120 can be configured with a side-wall aperture 132 through which the two ends 124, 126 of themovable element 122 can be routed. Thetorsional member 120 can be rotated by turning the distal end of thetorsional member 120. Thetorsional member 120 can be rotated in the opposite direction (of that shown by arrow 130) to allow the stent/graft to expand in the direction opposite ofarrows 128. The stent/graft can be compressed to allow rotational or longitudinal displacements within a vessel. When the desired placement is verified, the stent/graft can be allowed to expand and engage the vessel wall. Repeated compressions and expansions of the stent/graft can be utilized as desired. The stent/graft can also be gradually compressed or allowed to gradually expand by varying the amount of twist imparted to thetorsional member 120. After final placement of the stent/graft, tension can be applied to one of the moveable ends 124, 126 of themoveable element 122 to release and withdraw the movable element. -
FIGS. 2A and 2B are partial views of the proximal end of a medical apparatus according to a further embodiment of the invention, having releasable straps that can radial compress a stent/graft. - Referring to
FIGS. 2A and 2B , the medical apparatus is generally depicted asreference numeral 200. The medical apparatus ofFIGS. 2A and 2B is similar to the medical apparatus as shown inFIGS. 1A through 1C with a stent/graft not shown for clarity. - Shown in
FIG. 2A is a partial cross-section of a distal end of acatheter system 200 having anouter tube 202. Contained within theouter tube 202 are a firstinner tube 204 and atorsional member 206. Attached to the torsional member is at least oneflexible strap 208. Theflexible strap 208 surrounds a distal portion of a stent/graft (not shown). When thetorsional member 206 is rotated as depicted byarrow 210 thestrap 208 is further wound around thetorsional member 206, thereby “drawing in” the strap which will in turn, compress a surrounded stent/graft. The degree of stent/graft compression can be controlled by varying the amount of twist imparted to the torsional member. Afirst end 212 of aflexible strap 208 can be affixed to thetorsional member 206. Thesecond end 214 of thestrap 208 can be wrapped around the torsional member. When the medical apparatus is properly positioned with a target site, the torsional member can be rotated in a direction opposite that shown byarrow 210. This opposite rotation will allow the stent/graft to fully expand. Further opposite rotation of the torsional member will cause thestrap end 214 to “un-wind” from the torsional member. The torsional member can then be withdrawn in a distal direction, pulling the strap with attachedend 212 into the first inner tube. In an alternate method the first inner tube and the torsional member can be withdrawn together or all three members (204, 206, 208) can be withdrawn together. - Shown in
FIG. 2B is a non cross-sectional perspective view of the distal end of the catheter system shown inFIG. 2A . Theflexible straps 208 can be fabricated from various bio-compatible materials as commonly known in the art. -
FIGS. 3A and 3B are partial perspective views of a medical apparatus according to a further embodiment of the invention. - Referring to
FIGS. 3A and 3B , the medical apparatus is generally depicted asreference numeral medical apparatus 300A and B includescatheter assembly 102,stent 104 arranged on the proximal end portion of thecatheter assembly 102. Thestent 104 has an inner surface, an outer surface, and is configured from multiple turns of anundulating element 105. The undulatingelement 105 can be configured, for example, in a ring or helical pattern. - The
stent 104 has aproximal end portion 106 anddistal end portion 108. Thedistal end portion 108 is formed into a branch having afirst leg 110 and asecond leg 112. - A
graft member 114 is arranged about thestent 104. - The
stent 104 andgraft member 114 are constrained into a compacted delivery state by afirst sheath 116 andsecond sheath 118. As shown inFIGS. 3A and 3B , thefirst sheath 116 has been released allowing at least a portion of thestent 104 to expand as shown. Thesecond sheath 118 is coupling thesecond leg 112 to thecatheter assembly 102 as shown. - Shown in
FIG. 3A is a flexible constrainingsleeve 302, surrounding a proximal portion of the stent/graft. Atorsional member 120 extends from a proximal end portion to a distal end portion of thecatheter assembly 102. In the figure, thetorsional member 120 is positioned adjacent the outer surface of thestent 104 andgraft 114. Thetorsional member 120 is attached to thecatheter assembly 102 and not attached to thestent 104 orgraft 114. Theflexible sleeve 302 is attached to thetorsional member 120 so that when thetorsional member 120 is rotated, the flexible sleeve is compressed which in turn compresses the stent/graft. Theflexible sleeve 302 is shown having a parting orrip cord 304. Therip cord 304 can be in the form of a thread or wire that is contained within asecondary tube 306. Thesecondary tube 306 can exit the distal end of thecatheter assembly 102 with the rip cord exiting the distal end of the secondary tube. When the medical apparatus is properly deployed the distal end of the rip cord can be tensioned, thereby ripping or separating theflexible sleeve 302. Since the flexible sleeve is still attached to thetorsional member 120, theflexible sleeve 302 can then be withdrawn along with thecatheter assembly 102. - Shown in
FIG. 3B is a flexible constrainingsleeve 302, surrounding a proximal portion of the stent/graft. Atorsional member 310 extends from a proximal end portion to a distal end portion of thecatheter assembly 102. In the figure, thetorsional member 310 is positioned adjacent the outer surface of thestent 104 andgraft 114. Thetorsional member 310 is attached to thecatheter assembly 102 and not attached to thestent 104 orgraft 114. Theflexible sleeve 302 is attached to thetorsional member 310 so that when thetorsional member 310 is rotated, the flexible sleeve is compressed which in turn compresses the stent/graft. Theflexible sleeve 302 is shown having aparting line 312. Shown is a stitchedparting line 312 similar to those parting lines incorporated into the first 116 and second 118 sheaths. The release of the stitchedparting line 312 can be activated by arelease cord 314. Therelease cord 314 can be in the form of a thread or wire and can be contained within a secondary tube (not shown) or be contained within a catheter system lumen. Therelease cord 314 can exit the distal end of thecatheter assembly 102. When the medical apparatus is properly deployed the distal end of therelease cord 314 can be tensioned, thereby un-stitching or separating theflexible sleeve 302. Since the flexible sleeve is still attached to thetorsional member 310, theflexible sleeve 302 can then be withdrawn along with thecatheter assembly 102. - It will be apparent to those skilled in the art that various modifications and variation can be made in the present invention without departing from the spirit or scope of the invention. Thus, it is intended that the present invention cover the modifications and variations of this invention provided they come within the scope of the appended claims and their equivalents.
Claims (13)
1. An apparatus, comprising:
a catheter having a proximal end portion and distal end portion;
a stent arranged on the proximal end portion of the catheter, the stent having an inner surface and an outer surface;
a graft member arranged about the stent member; and
a movable element connected to a torsional member, wherein the torsional member is capable of retracting a portion of the movable element and thereby radially compressing at least a portion of the stent.
2. The apparatus of claim 1 , further comprising a tube having a proximal end portion and distal end portion arranged on at least a portion of the stent, wherein at least a portion of the torsional member extends within a portion of the tube.
3. The apparatus of claim 2 , wherein the distal end portion of the tube extends to a hub arranged on the distal end portion of the catheter.
4. The apparatus of claim 2 , wherein the tube comprises two lumens.
5. The apparatus of claim 1 , wherein the movable element comprises a filament.
6. The apparatus of claim 5 , wherein the filament comprises a wire.
7. The apparatus of claim 5 , wherein the filament comprises a polymer.
8. The apparatus of claim 7 , wherein the polymer comprises a fluoropolymer.
9. The apparatus of claim 8 , wherein the fluoropolymer comprises polytetrafluoroethylene.
10. The apparatus of claim 9 , wherein the polytetrafluoroethylene comprises expanded polytetrafluoroethylene.
11. The apparatus of claim 5 , wherein the filament is arranged circumferentially around the graft member and is threaded between adjacent undulations of the stent.
12. The apparatus of claim 1 , wherein the tubular graft member is positioned on an inside portion of the stent.
13. The apparatus of claim 2 , wherein the tube is positioned on an inside portion of the stent.
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Also Published As
Publication number | Publication date |
---|---|
JP2011522592A (en) | 2011-08-04 |
WO2009148607A1 (en) | 2009-12-10 |
US20150051691A1 (en) | 2015-02-19 |
CA2725736A1 (en) | 2009-12-10 |
AU2009255613B2 (en) | 2013-09-19 |
US10905576B2 (en) | 2021-02-02 |
EP2282705A1 (en) | 2011-02-16 |
AU2009255613A1 (en) | 2009-12-10 |
US9907683B2 (en) | 2018-03-06 |
US20180193178A1 (en) | 2018-07-12 |
JP5536764B2 (en) | 2014-07-02 |
CA2725736C (en) | 2013-09-17 |
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