US3654085A - Storage device for organ transplants - Google Patents

Storage device for organ transplants Download PDF

Info

Publication number
US3654085A
US3654085A US877217A US3654085DA US3654085A US 3654085 A US3654085 A US 3654085A US 877217 A US877217 A US 877217A US 3654085D A US3654085D A US 3654085DA US 3654085 A US3654085 A US 3654085A
Authority
US
United States
Prior art keywords
chamber
blood
pump
storage device
motor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US877217A
Inventor
Artur Valter Leopold Norr
Fritz Bertil Willy Holm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGA AB
Original Assignee
AGA AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AGA AB filed Critical AGA AB
Application granted granted Critical
Publication of US3654085A publication Critical patent/US3654085A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects

Definitions

  • a pressure chamber for storing organic transplants and supplying them With oxygenated blood is provided with an oxygenator and a blood pump in the chamber.
  • the pump is driven from a motor outside the chamber so as to avoid pressure influence on the blood, a pressuretight transmission connecting the motor with the pump through the chamber wall.
  • the invention relates to a device for storage and blood perfusion of an organic transplant.
  • This type of storage requires a continuous supply of oxygenated blood to the transplant in order to keep it in fresh condition.
  • An oxygenator is provided in the chamber and a blood pump is also necessary to collect blood from the oxygenator and supply it to the transplant, which may be a heart or a liver or some other organ.
  • the characteristic feature of the invention consists in that the blood pump is located in the chamber, whereas the motor is placed outside it, a transmission being provided for connecting the motor with the pump through the wall of the chamber in an air-tight manner.
  • the storage device comprises a chamber having a cylindrical wall V with a window F provided therein for observation of the interior of the chamber.
  • a container B Inserted in the chamber is a container B which is supported by a plate S.
  • the plate S rests on guides SK, on which container B can be pushed into or pulled out of the chamber.
  • the container has a lid, in which a window F is provided in a position corresponding to that of window F.
  • the organic transplant is indicated by L and the artery A thereof is connected via a lead-through at G to a tube SL, which connects the same with the outlet of a blood pump BP.
  • the blood issuing from transplant L flows into an oxygenator OX, from which a conduit L' leads to the inlet of blood pump BP.
  • the axle AX of blood pump BP is brought out through the chamber wall via a bushing H to connect with a motor M. Also, placed outside the chamber is a pump P for supplying oxygen or air to the chamber under increased pressure via conduits R and lead-throughs G and. G".
  • the arrangement of blood pump BP within the chamber removes the drawbacks referred to above, which are present if the blood, is to be brought out of the chamber and back after passage through the pump. There is less energy required to be supplied by the pump and the danger of haemolysis is substantially reduced. This advantage is particularly noticeable in connection with a blood pump of a type known per se comprising elastic tubing which is compressed by rotating rollers moving over the tubing for feeding the blood.
  • the lead-through H referred to above may be of any known type which is capable of withstanding a pressure of about 5 to 10 at.
  • the pump P can be replaced by some other type of gas supply, such as a container for gas under increased pressure.
  • a device for the storage and blood perfusion of organic transplants comprising:
  • a pump device in said chamber for maintaining a stream of blood
  • first conduit means for conveying said stream of blood from said pump to said organ
  • an oxygenator in said chamber positioned to receive blood from said organ
  • a device as claimed in claim 1 which includes a support for holding a transplant slidable in said chamber and supporting said oxygenator.

Abstract

A PRESSURE CHAMBER FOR STORING ORGANIC TRANSPLANT AND SUPPLYING THEM WITHIN OXYGENATED BLOOD IS PROVIDED WITH AN OXYGENATOR AND A BLOOD PUMP IN THE CHAMBER. THE PUMP IS DRIVEN FROM A MOTOR OUTSIDE THE CHAMBER SO AS TO AVOID PRESSURE INFLUENCE ON THE BLOOD, A PRESSURETIGHT TRANSMISSION CONNECTING THE MOTOR WITH THE PUMP THROUGH THE CHAMBER WALL.

Description

April 4, 1972 A. v. L. NORR ErAL STORAGE DEVICE FOR ORGAN TRANSPLANTS Filed Nov. 17, 1969 INVENTORS ARTUR VALTER LEOPOLD NORR FRITZ BERTIL WILLY HOLM m 32592 ATTORNEYS United States Patent 3,654,085 STORAGE DEVICE FOR ORGAN TRANSPLANTS Artur Valter Leopold Norr and Fritz Bertil Willy Holm, Lidingo, Sweden, assignors to AGA Aktiebolag, Lidingo, Sweden Filed Nov. 17, 1969, Ser. No. 877,217 Claims priority, application Sweden, Nov. 26, 1968, 16,077/ 68 Int. Cl. A61b 19/00 U.S. Cl. 195-127 3 Claims ABSTRACT OF THE DISCLOSURE A pressure chamber for storing organic transplants and supplying them With oxygenated blood is provided with an oxygenator and a blood pump in the chamber. The pump is driven from a motor outside the chamber so as to avoid pressure influence on the blood, a pressuretight transmission connecting the motor with the pump through the chamber wall.
BACKGROUND OF THE INVENTION The invention relates to a device for storage and blood perfusion of an organic transplant.
This type of storage requires a continuous supply of oxygenated blood to the transplant in order to keep it in fresh condition. An oxygenator is provided in the chamber and a blood pump is also necessary to collect blood from the oxygenator and supply it to the transplant, which may be a heart or a liver or some other organ.
If, in a chamber of the type referred to, the blood pump is placed outside the chamber, lead-through conduits for the perfusion blood are required from the interior of the chamber to the pump and from the latter back into the chamber. This requires the blood to overcome the pressure differential between the outside and the interior of the chamber and a corresponding amount of energy must be supplied by the pump. Also, there is an increased danger of haemolysis of the blood.
SUMMARY OF THE INVENTION It is an object of the invention to provide a storage device which obviates the disadvantage referred to. The characteristic feature of the invention consists in that the blood pump is located in the chamber, whereas the motor is placed outside it, a transmission being provided for connecting the motor with the pump through the wall of the chamber in an air-tight manner.
THE DRAWING The attached drawing shows an embodiment of the invention.
DESCRIPTION OF EMBODIMENT The storage device comprises a chamber having a cylindrical wall V with a window F provided therein for observation of the interior of the chamber. Inserted in the chamber is a container B which is supported by a plate S. The plate S rests on guides SK, on which container B can be pushed into or pulled out of the chamber. The container has a lid, in which a window F is provided in a position corresponding to that of window F. The organic transplant is indicated by L and the artery A thereof is connected via a lead-through at G to a tube SL, which connects the same with the outlet of a blood pump BP. The blood issuing from transplant L flows into an oxygenator OX, from which a conduit L' leads to the inlet of blood pump BP. The axle AX of blood pump BP is brought out through the chamber wall via a bushing H to connect with a motor M. Also, placed outside the chamber is a pump P for supplying oxygen or air to the chamber under increased pressure via conduits R and lead-throughs G and. G".
Owing to the fact that the pressure gas is supplied via lead-through G" to container B there is a direct supply of fresh air or oxygen to the transplant.
The arrangement of blood pump BP within the chamber removes the drawbacks referred to above, which are present if the blood, is to be brought out of the chamber and back after passage through the pump. There is less energy required to be supplied by the pump and the danger of haemolysis is substantially reduced. This advantage is particularly noticeable in connection with a blood pump of a type known per se comprising elastic tubing which is compressed by rotating rollers moving over the tubing for feeding the blood.
The lead-through H referred to above may be of any known type which is capable of withstanding a pressure of about 5 to 10 at.
The pump P can be replaced by some other type of gas supply, such as a container for gas under increased pressure.
We claim:
1. A device for the storage and blood perfusion of organic transplants comprising:
a chamber capable of holding gas under increased pressure,
means for supporting an organ in said chamber,
a pump device in said chamber for maintaining a stream of blood,
first conduit means for conveying said stream of blood from said pump to said organ,
an oxygenator in said chamber positioned to receive blood from said organ,
second conduit means for conveying blood from said oxygenator to said pump,
a motor outside of said chamber for driving said pump, and
a transmission member connecting said motor with said pump device through the wall of said chamber in an airtight manner.
2. A device as claimed in claim 1, in which said pump device comprises a flexible tube and rollers movable along said tube and compressing the same.
3. A device as claimed in claim 1, which includes a support for holding a transplant slidable in said chamber and supporting said oxygenator.
References Cited UNITED STATES PATENTS 1(1/ 1968 Swenson et al. 62--306 12/1970 Swenson et al. 62-231 OTHER REFERENCES A. LOUIS MONACELL, Primary Examiner R. B. ANDEWELT, Assistant Examiner U.S. Cl. X.R.
l28--Heart-Lung Digest
US877217A 1968-11-26 1969-11-17 Storage device for organ transplants Expired - Lifetime US3654085A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE16077/68A SE323475B (en) 1968-11-26 1968-11-26

Publications (1)

Publication Number Publication Date
US3654085A true US3654085A (en) 1972-04-04

Family

ID=20301697

Family Applications (1)

Application Number Title Priority Date Filing Date
US877217A Expired - Lifetime US3654085A (en) 1968-11-26 1969-11-17 Storage device for organ transplants

Country Status (7)

Country Link
US (1) US3654085A (en)
JP (1) JPS4840996B1 (en)
CH (1) CH500720A (en)
DE (1) DE1958314A1 (en)
FR (1) FR2024286A1 (en)
GB (1) GB1288926A (en)
SE (1) SE323475B (en)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3777507A (en) * 1971-11-24 1973-12-11 Waters Instr Inc Renal preservation system
US4837390A (en) * 1983-05-11 1989-06-06 Keyes Offshore, Inc. Hyperbaric organ preservation apparatus and method for preserving living organs
US6673594B1 (en) 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US20040111104A1 (en) * 2002-08-23 2004-06-10 Organ Recovery Systems Cannulas, cannula mount assemblies, and clamping methods using such cannulas and cannula mount assemblies
US20040171138A1 (en) * 2002-08-14 2004-09-02 Transmedics, Inc. Heart preservation chamber
US20040221719A1 (en) * 2003-04-04 2004-11-11 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
US20040224299A1 (en) * 2003-04-04 2004-11-11 Organ Recovery Systems Method and apparatus for transferring heat to or from an organ or tissue container
US20040224298A1 (en) * 1998-09-29 2004-11-11 John Brassil Apparatus and method for determining effects of a substance of an organ
US20060063142A1 (en) * 1998-09-29 2006-03-23 Organ Recovery Systems, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US20060148062A1 (en) * 2004-10-07 2006-07-06 Transmedics, Inc. Systems and methods for ex-vivo organ care
US20060154357A1 (en) * 2004-10-07 2006-07-13 Transmedics, Inc. Systems and methods for ex-vivo organ care
US20080234768A1 (en) * 2007-03-20 2008-09-25 Transmedics, Inc Systems for monitoring and applying electrical currents in an organ perfusion system
US20090197292A1 (en) * 2008-01-31 2009-08-06 Transmedics, Inc Systems and methods for ex vivo lung care
US20110136096A1 (en) * 2006-04-19 2011-06-09 Transmedics, Inc. Systems and Methods for Ex Vivo Organ Care
US8828034B2 (en) 2011-04-29 2014-09-09 Lifeline Scientific, Inc. Cannula
US9022978B2 (en) 2011-04-29 2015-05-05 Lifeline Scientific, Inc. Universal sealring cannula
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9320269B2 (en) 2009-09-25 2016-04-26 John Brassil Organ preservation system
US9642625B2 (en) 2011-04-29 2017-05-09 Lifeline Scientific, Inc. Cannula for a donor organ with or without an aortic cuff or patch
US9756851B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US9894894B2 (en) 2004-10-07 2018-02-20 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US10076112B2 (en) 2014-06-02 2018-09-18 Transmedic, Inc. Ex vivo organ care system
US10194655B2 (en) 2015-09-09 2019-02-05 Transmedics, Inc. Aortic cannula for ex vivo organ care system
US11856944B2 (en) 2011-04-14 2024-01-02 Transmedics, Inc. Organ care solution for ex-vivo machine perfusion of donor lungs

Cited By (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3777507A (en) * 1971-11-24 1973-12-11 Waters Instr Inc Renal preservation system
US4837390A (en) * 1983-05-11 1989-06-06 Keyes Offshore, Inc. Hyperbaric organ preservation apparatus and method for preserving living organs
US9756849B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US9756850B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US9756851B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US8431385B2 (en) 1998-09-29 2013-04-30 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US20100221696A1 (en) * 1998-09-29 2010-09-02 Organ Recovery Systems, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US20040224298A1 (en) * 1998-09-29 2004-11-11 John Brassil Apparatus and method for determining effects of a substance of an organ
US20060063142A1 (en) * 1998-09-29 2006-03-23 Organ Recovery Systems, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US8268547B2 (en) 1998-09-29 2012-09-18 Lifeline Scientific, Inc. Method of transporting and storing a kidney
US6673594B1 (en) 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US8609400B2 (en) 1998-09-29 2013-12-17 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US8962303B2 (en) 1998-09-29 2015-02-24 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US8445260B2 (en) 1998-09-29 2013-05-21 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US8420381B2 (en) 1998-09-29 2013-04-16 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US20110129908A1 (en) * 1998-09-29 2011-06-02 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US20110059429A1 (en) * 1998-09-29 2011-03-10 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US8349551B2 (en) 1998-09-29 2013-01-08 Lifeline Scientific, Inc. Method for controlling perfusion of an organ
US20110053256A1 (en) * 1998-09-29 2011-03-03 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US8318415B2 (en) 1998-09-29 2012-11-27 Lifeline Scientific, Inc. Method of determining transport and/or storage parameters for maintaining viability of an organ
US7749693B2 (en) 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
US8268612B2 (en) 1998-09-29 2012-09-18 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US7824848B2 (en) 1998-09-29 2010-11-02 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US20110039253A1 (en) * 1998-09-29 2011-02-17 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US8323954B2 (en) 2000-08-25 2012-12-04 Lifeline Scientific, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US7572622B2 (en) 2002-08-14 2009-08-11 Transmedic, Inc. Heart preservation chamber
US20040171138A1 (en) * 2002-08-14 2004-09-02 Transmedics, Inc. Heart preservation chamber
US8361091B2 (en) 2002-08-23 2013-01-29 Organ Recovery Systems, Inc. Cannulas, cannula mount assemblies, and clamping methods using such cannulas and cannula mount assemblies
US20040111104A1 (en) * 2002-08-23 2004-06-10 Organ Recovery Systems Cannulas, cannula mount assemblies, and clamping methods using such cannulas and cannula mount assemblies
US7998725B2 (en) 2003-04-04 2011-08-16 Organ Recovery Systems Method and apparatus for holding a plurality of tubes connectible to an organ or tissue container
US20040221719A1 (en) * 2003-04-04 2004-11-11 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
US8097449B2 (en) 2003-04-04 2012-01-17 Organ Recovery Systems Method and apparatus for transferring heat to or from an organ or tissue container
US20040224299A1 (en) * 2003-04-04 2004-11-11 Organ Recovery Systems Method and apparatus for transferring heat to or from an organ or tissue container
US20100151559A1 (en) * 2003-04-04 2010-06-17 Lifeline Scientific, Inc. Method and apparatus for transferring heat to or from an organ or tissue container
US20100112542A1 (en) * 2003-04-04 2010-05-06 Organ Recovery Systems, Inc. Method and apparatus for controlling air pressure in an organ or tissue container
US7691622B2 (en) 2003-04-04 2010-04-06 Lifeline Scientific, Inc. Method and apparatus for transferring heat to or from an organ or tissue container
US7678563B2 (en) 2003-04-04 2010-03-16 Organ Recovery Systems, Inc. Method and apparatus for controlling air pressure in an organ or tissue container
US8389271B2 (en) 2003-04-04 2013-03-05 Organ Recovery Systems, Inc. Method and apparatus for controlling air pressure in an organ or tissue container
US8128740B2 (en) 2003-04-04 2012-03-06 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
US11570985B2 (en) 2004-10-07 2023-02-07 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US11191263B2 (en) 2004-10-07 2021-12-07 Transmedics, Inc. Systems and methods for ex-vivo organ care
US10321676B2 (en) 2004-10-07 2019-06-18 Transmedics, Inc. System and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US10314303B2 (en) 2004-10-07 2019-06-11 Transmedics, Inc. Systems and methods for ex-vivo organ care
US10736314B2 (en) 2004-10-07 2020-08-11 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US11723357B2 (en) 2004-10-07 2023-08-15 Transmedics, Inc. Systems and methods for ex-vivo organ care
US9894894B2 (en) 2004-10-07 2018-02-20 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9055740B2 (en) 2004-10-07 2015-06-16 Transmedics, Inc. Systems and methods for ex-vivo organ care
US20060154357A1 (en) * 2004-10-07 2006-07-13 Transmedics, Inc. Systems and methods for ex-vivo organ care
US9215867B2 (en) 2004-10-07 2015-12-22 Transmedics, Inc. Systems and methods for ex-vivo organ care
US20060148062A1 (en) * 2004-10-07 2006-07-06 Transmedics, Inc. Systems and methods for ex-vivo organ care
US9301519B2 (en) 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US10039276B2 (en) 2005-06-28 2018-08-07 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US11844345B2 (en) 2005-06-28 2023-12-19 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US20110136096A1 (en) * 2006-04-19 2011-06-09 Transmedics, Inc. Systems and Methods for Ex Vivo Organ Care
US8822203B2 (en) 2006-04-19 2014-09-02 Transmedics, Inc. Systems and methods for ex vivo organ care
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US20080234768A1 (en) * 2007-03-20 2008-09-25 Transmedics, Inc Systems for monitoring and applying electrical currents in an organ perfusion system
US11917991B2 (en) 2007-03-20 2024-03-05 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US10327443B2 (en) 2007-03-20 2019-06-25 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US9247728B2 (en) 2008-01-31 2016-02-02 Transmedics, Inc. Systems and methods for ex vivo lung care
US9814230B2 (en) 2008-01-31 2017-11-14 Transmedics, Inc. Systems and methods for ex vivo lung care
US20090197292A1 (en) * 2008-01-31 2009-08-06 Transmedics, Inc Systems and methods for ex vivo lung care
US20090197325A1 (en) * 2008-01-31 2009-08-06 Transmedics, Inc SYSTEMS AND METHODS FOR Ex vivo LUNG CARE
US20090197240A1 (en) * 2008-01-31 2009-08-06 Transmedics, Inc Systems and methods for ex vivo lung care
US9516875B2 (en) 2008-01-31 2016-12-13 Transmedics, Inc. Systems and methods for ex vivo lung care
US9462802B2 (en) 2008-01-31 2016-10-11 Transmedics, Inc. Systems and methods for ex vivo lung care
US10750738B2 (en) 2008-01-31 2020-08-25 Transmedics, Inc. Systems and methods for ex vivo lung care
US9320269B2 (en) 2009-09-25 2016-04-26 John Brassil Organ preservation system
US11856944B2 (en) 2011-04-14 2024-01-02 Transmedics, Inc. Organ care solution for ex-vivo machine perfusion of donor lungs
US9022978B2 (en) 2011-04-29 2015-05-05 Lifeline Scientific, Inc. Universal sealring cannula
US8828034B2 (en) 2011-04-29 2014-09-09 Lifeline Scientific, Inc. Cannula
US9642625B2 (en) 2011-04-29 2017-05-09 Lifeline Scientific, Inc. Cannula for a donor organ with or without an aortic cuff or patch
US11154050B2 (en) 2014-06-02 2021-10-26 Transmedics, Inc. Ex vivo organ care system
US10076112B2 (en) 2014-06-02 2018-09-18 Transmedic, Inc. Ex vivo organ care system
US11903381B2 (en) 2014-06-02 2024-02-20 Transmedics, Inc. Ex vivo organ care system
US11944088B2 (en) 2014-06-02 2024-04-02 Transmedics, Inc. Ex vivo organ care system
US11122795B2 (en) 2015-09-09 2021-09-21 Transmedics, Inc. Aortic cannula for ex vivo organ care system
US10194655B2 (en) 2015-09-09 2019-02-05 Transmedics, Inc. Aortic cannula for ex vivo organ care system

Also Published As

Publication number Publication date
SE323475B (en) 1970-05-04
FR2024286A1 (en) 1970-08-28
DE1958314A1 (en) 1970-06-11
CH500720A (en) 1970-12-31
GB1288926A (en) 1972-09-13
JPS4840996B1 (en) 1973-12-04

Similar Documents

Publication Publication Date Title
US3654085A (en) Storage device for organ transplants
US4745759A (en) Kidney preservation machine
GB1314279A (en) Preservation of organs
ES2046239T3 (en) CONNECTION FOR CATHETERS, PERFUSION EQUIPMENT AND BOTTLES OF LIQUIDS TO BE PERFUSED.
PT99069A (en) MEDICINAL CONTAINER AIR CONDITIONING
GB1480526A (en) Blood oxygenator
US4446229A (en) Method of tissue growth
JPS59212401A (en) Internal organ preserving device and method
GB1249150A (en) Apparatus for monitoring heart blood pressure
GB1397695A (en) Blood oxygenation device
ES2050580A1 (en) Solutions for the perfusion, preservation and reperfusion of organs
GB1046098A (en) Improvements in or relating to devices for circulating blood
ES384560A2 (en) Apparatus for wet treatment of warp-rope or board-shaped textile goods
CN115155431A (en) Disinfection supply room keeps apart receiving arrangement that weighs
Braems et al. Hypoxia reduces oxygen consumption of fetal skeletal muscle cells in monolayer culture
GB1454795A (en) Portable anaesthetic unit
JPH0269401A (en) Organ preserving device
SE9801421L (en) vent
GB1422356A (en) Apparatus for use in storing body tissue
GB1325667A (en) Container especially for organ perfusion
US2527716A (en) Spirometer apparatus for determining the characteristic of metabolism
SU141985A1 (en) Device for testing biological preparations on isolated organs of animals
Tepper et al. A METHOD OF DETECTING MICRO-BUBBLES RESULTING FROM THE PASSAGE OF BLOOD THROUGH HEART LUNG MACHINE
JP2017147947A (en) Agitation mechanism of cell culture device, cell culture module, and cell culture device
JP2022172470A (en) Experimental system particularly for use in microscopy