US3788374A - Parenteral solution bag - Google Patents

Parenteral solution bag Download PDF

Info

Publication number
US3788374A
US3788374A US00220763A US3788374DA US3788374A US 3788374 A US3788374 A US 3788374A US 00220763 A US00220763 A US 00220763A US 3788374D A US3788374D A US 3788374DA US 3788374 A US3788374 A US 3788374A
Authority
US
United States
Prior art keywords
tab
bag
port tube
protective closure
closure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US00220763A
Inventor
M Saijo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jintan Terumo Co Ltd
Original Assignee
Jintan Terumo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jintan Terumo Co Ltd filed Critical Jintan Terumo Co Ltd
Application granted granted Critical
Publication of US3788374A publication Critical patent/US3788374A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C59/00Surface shaping of articles, e.g. embossing; Apparatus therefor
    • B29C59/007Forming single grooves or ribs, e.g. tear lines, weak spots
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/18Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using heated tools
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/74Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area
    • B29C65/745Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area using a single unit having both a severing tool and a welding tool
    • B29C65/7451Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area using a single unit having both a severing tool and a welding tool the severing tool and the welding tool being movable with respect to one-another
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/01General aspects dealing with the joint area or with the area to be joined
    • B29C66/05Particular design of joint configurations
    • B29C66/10Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/11Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
    • B29C66/112Single lapped joints
    • B29C66/1122Single lap to lap joints, i.e. overlap joints
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/01General aspects dealing with the joint area or with the area to be joined
    • B29C66/32Measures for keeping the burr form under control; Avoiding burr formation; Shaping the burr
    • B29C66/326Shaping the burr, e.g. by the joining tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/40General aspects of joining substantially flat articles, e.g. plates, sheets or web-like materials; Making flat seams in tubular or hollow articles; Joining single elements to substantially flat surfaces
    • B29C66/41Joining substantially flat articles ; Making flat seams in tubular or hollow articles
    • B29C66/43Joining a relatively small portion of the surface of said articles
    • B29C66/431Joining the articles to themselves
    • B29C66/4312Joining the articles to themselves for making flat seams in tubular or hollow articles, e.g. transversal seams
    • B29C66/43121Closing the ends of tubular or hollow single articles, e.g. closing the ends of bags
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/80General aspects of machine operations or constructions and parts thereof
    • B29C66/83General aspects of machine operations or constructions and parts thereof characterised by the movement of the joining or pressing tools
    • B29C66/832Reciprocating joining or pressing tools
    • B29C66/8322Joining or pressing tools reciprocating along one axis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1475Inlet or outlet ports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2793/00Shaping techniques involving a cutting or machining operation
    • B29C2793/0054Shaping techniques involving a cutting or machining operation partially cutting through the material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C37/00Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
    • B29C37/0053Moulding articles characterised by the shape of the surface, e.g. ribs, high polish
    • B29C37/0057Moulding single grooves or ribs, e.g. tear lines
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/712Containers; Packaging elements or accessories, Packages
    • B29L2031/7148Blood bags, medical bags

Definitions

  • a parenteral solution bag is provided with openings [51 Int. Cl. B65d p r ing fr m he perimeter of said bag for taking in [58] Field of Search 150/1, 8, 3; 229/66, 62; or out parenteral solution and with a protective clo- 128/272, 227, 214 B, DIG. 24 Sure for hermetically enclosing this protruded portion.
  • v To the protective closure of the protruding portion is [56] References Cit d fused part of a tab for tearing said protective closure.
  • the present invention relates to a parenteral solution bag, particularly to a parenteral solution bag improved in the mechanism for hermetically sealing the opening for taking in or out parenteral solution.
  • a conventional hermetically sealing mechanism for this kind of bag is a rubber plug sealing in which the outlet opening is sealed with rubber plugs,.
  • This type of sealing has many disadvantages: e.g., it is inconvenient to open the seal, the seal is easily polluted after it is opened, the outlet opening is easily polluted when opened, and sterilization of the rubber plug portion is difficult to effect.
  • the object of the present invention is to provide a parenteral solution bag having a simple sealing mechanism, not pollutable in the inlet and outlet of parenteral solution while hermetically sealed and when unsealed, and sterilizable as a whole under hermetically sealed condition such as in an autoclave, thus eliminating the above-mentioned drawbacks of conventional parenteral solution bags.
  • Another object of the invention is to provide a parenteral solution bag capable of having its tab peeled easily and reliably, being conveniently handled when opened and also being safely operated from a hygienic point of VI ⁇ V.
  • FIG. 1 is a plan view of a parenteral solution bag according to the present invention
  • FIG. 2 is a perspective view of the outlet of the parenteral solution bag
  • FIG. 3 is a cross-sectional view taken along IIIIII line of FIG. 1;
  • FIGS. 4 to 6 are sectional views showing the process of heat sealing the tab to the protective closure
  • FIG. 7 is a sectional view of the tab while it is peeled.
  • FIGS. 8 to 12 are lateral views showing the sequential processes of exposing the outlet of the parenteral solution bag.
  • the reference numeral 11 denotes a parenteral solution bag of a pliable and transparent plastic such as polyvinyl chloride which contains a proper quantity of ACD solution inside and the perimeter 11a of which is heat sealed. From a part of said perimeter 11a are derived a tubular extension 13 connected to a blood drawing needle 12 and a pair of solution ports 14. The numeral indicates a ball valve. Each port 14 is in the form of a hollow cylinder, one end being open to the inside of the bag 11 and the other end open to the outside of the bag 11. Between said two openings is stretched a diaphragm 15, through which a cannula can be pierced into the bag 11 and which prevents the outflow of the liquid existing inside bag 11.
  • a diaphragm 15 Between said two openings is stretched a diaphragm 15, through which a cannula can be pierced into the bag 11 and which prevents the outflow of the liquid existing inside bag 11.
  • protective closures l6 hermetically cover the whole ports 14 so as to prevent the pollution of the ports 14.
  • Each protective closure 16 forms a bag and is provided with a tab 17 on one face.
  • the base end portion 17a of the tab 17 is fused to the protruding front of said protective closure 16 and the other end portion 17b of said tab 17 is lapped over the surface of the protective closure 16 toward the end connected with the parenteral solution bag as a gripping means.
  • the seal 18 between the joined base portion 17a and the free end portion 17b of tab 17 is so arranged that is preferably placed over the port 14 and roughly V- shaped.
  • this invention consists in, as illustrated in FIGS. 4 to 7, heat sealing the tab 17 to the protective closure 16 in the direction in which the latter is set in place and fusing together the sheets of both closure 16 and tab 17 to form a V-shaped groove extending into the tab 17.
  • the heater 20 is forced into the mass until its end reaches the tab 17 to fuse both sheets together (FIG. 5).
  • the heater 20 is taken off, there is obtained a V-shaped groove 18a, on both sides of which there are formed upward projecting ribs 18b.
  • Another heater 21 is intended to ensure the full fusion of the tab 17 to the protective closure 16, thereby increasing the flexural strength of the tab 17 when it is peeled. As shown in FIGS. 4 and 5, the latter heater 21 is placed adjacent to the first mentioned heater 20 to produce both heat seals simultaneously.
  • the latter heater 21 is intended simply to ensure the tight fusion of the tab 17 to the protective closure 16, and also to form ribs 22 so as to elevate the flexural strength of the tab 17, the latter heater 21 need not be inserted into the superposed mass so deeply as the first mentioned heater 20.
  • the boundary (A) between the fused and nonfused portions of the protective closure 16 becomes slightly thinned, as shown in FIG. 7, and in consequence is reduced in tear strength, permitting its easy breakage when the tab 17 is pulled.
  • the sheets of both protective closure 16 and tab 17 originally had the same thickness, the protective closure 16 alone is sure to be broken, eliminating the necessity of making the sheet of the tab 17 thicker than that of the protective closure 16.
  • This offers in manufacture the advantage of using plastic sheets of the same material and thickness in common to the protective closure 16 and tab 17.
  • a pliable and transparent film such as soft polyvinyl chloride film or polyolefin resin film may be used.
  • the protective closure 16 has a thickness of a 0.4 mm and an inner width (Y) of about 16 mm as against the port 14 having a diameter (X) of about 7 mm, and the distance (Z) between the end of the port 14 and the inner end of the protective closure 16 is about 5 mm.
  • the tab 17 consists of the same kind of plastic sheet as the protective closure 16, and is heat sealed thereto in advance by the process illustrated in FIGS. 4 to 6. As apparent from FlG. 2, the final heat seal pattern is such that the side of the base portion of the tab 17 which faces the parenteral solution bag 11 is formed into a pyramidic shape above the port 14 with the pointed top of said pyramidic shape disposed slightly above the diaphragm 15. When, as shown in FIG.
  • the port 14 is bent to peel off the tab 17 with its free end 17b gripped by hand, the boundary between the port 14 and diaphragm 15 is naturally bent, enabling said free end portion 17b to be easily gripped.
  • the tab 17 can be peel off, as illustrated in FIG. 9, without loss of the peeling force.
  • the pyramidic heat sealed pattern is not limited to what is indicated, but any other similar pattern may be accepted, provided that it causes the peeling force to be concentrated at a point so as to permit the easy removal of the tab 17.
  • end 16b of the protective closure 16 is not provided with a V-shaped groove illustrated in FIGS. 4 to 6, but is fully heat sealed by the ordinary method used in fusing together laminated sheets. When, therefore, the tab 17 is peeled off, said end 16b of the protective closure 16 is not taken off together with the tab 17.
  • the protective closure 16 and tab 17 jointly act as a spring to the finger when it presses the tab 17 from the inside, preventing the tab 17 from getting away from the finger.
  • the finger can be inserted fully into the protective closure 16 so as to easily expose the port 14.
  • the tab 17 plays the part of holding the finger. Namely, the tab 17 not only serves to tear open the protective closure 16, but also acts as a stopper for preventing the finger from slipping.
  • the parenteral solution bag 11 provided with ports 14 having above-mentioned structure and arranged in the periphery of bag 11' is convenient to manufacture compared with the case in which ports are arranged in the bag face.
  • the advantage of the present parenteral solution bag also lies in that there are further advantages that plastic sheets of the same material and thickness are used for both the protective closure and tab; the tab is unfailingly peeled off; the joint of the protective closure and the tab is easily broken by the peeling of the latter; the tab concurrently acts as a stopper when it is peeled; and the cannula is easily inserted.
  • parenteral solution may be taken out while the bag is suspended by means of a hanger hole 23. There is no possibility for hands to touch ports 14, and this is a merit from a hygienic point of view.
  • a parenteral solution bag comprising at least one port tube protruding from part of the perimeter of the bag and hermetically enclosed by a bag-like protective closure, a diaphragm provided in the port tube sealing off the port tube from flow-off liquid within the bag through the port tube, and a tab peripherally heat sealed to a portion of said protective closure having an unsealed free end, the improvement which comprises in combination:
  • V-shaped groove extending through said protective closure and into said tab, said tab and said closure being connected by a heat seal which extends along the periphery of said groove, and a pair of ribs on said closure, said ribs extending adjacent I said groove, 1 c. the apex of said V-shaped groove facing toward the junction of said port tube with said bag, d. said V-shaped groove being positioned over said I port tube and extending transversely to the port k tube, and i e.
  • the heat sealed portion of said tab being more rigid l than the portion of said protective closure not sealed to said tab so that when the tab is peeled and turned backward towards the opposite side of said port tube, said heat sealed portion of said tab does not bend but instead said portion of said protective closure not sealed to said tube bends.
  • the parenteral solution bag of claim 1 wherein said protective closure is a rectangular shaped envelope formed of plastic sheet heat sealed along the two longest sides and one of the shorter sides, the other short side is heat sealed to said bag with said port tube enclosed by said protective closure and said V-shaped groove faces inward toward said port tube and extends from the heat seal along one of said longest sides to the heat seal along the other longest side.

Abstract

A parenteral solution bag is provided with openings protruding from the perimeter of said bag for taking in or out parenteral solution and with a protective closure for hermetically enclosing this protruded portion. To the protective closure of the protruding portion is fused part of a tab for tearing said protective closure.

Description

D United States Patent 1191 1111 3,788,374 SaijO Jan. 29, 1974 [54] PARENTERAL SOLUTION BAG 3,110,308 11/1963 Bellamy, Jr. 128/272 x I 3,426,959 2/1969 Lemelson [75] nvenmr- Sail, FUJmOmYa Japan 3,339,825 9/1967 Grevich 150/3 x [73] Assignee: Jintan Terumo Co., Ltd., Tokyo,
Japan Primary Examiner-William T. Dixson, Jr. [22] plied 1972 Assistant Examiner-Stephen P. Garbe [21] Appl. No.: 220,763 Attorney, Agent, or Firm-Kemon. Palmer -&
Related US. Application Data Estabrook [63] Continuation-impart of Ser. No. 71,309, Sept. 11,
1970, abandoned. [57] ABSTRACT [521 US. Cl. 150/1, 128/214 B, 128/272,
ISO/8, 229/66 A parenteral solution bag is provided with openings [51 Int. Cl. B65d p r ing fr m he perimeter of said bag for taking in [58] Field of Search 150/1, 8, 3; 229/66, 62; or out parenteral solution and with a protective clo- 128/272, 227, 214 B, DIG. 24 Sure for hermetically enclosing this protruded portion. v To the protective closure of the protruding portion is [56] References Cit d fused part of a tab for tearing said protective closure.
UNITED STATES PATENTS 3,343,541 9/1967 I Bellam Jr, 128/272 3 Claims, 12 Drawing Figures PATENTEDmzsmm 37883 sum 20F 2 FIGS "F169 FIG-'10 PARENTERAL SOLUTION BAG CROSS-REFERENCE TO RELATED APPLICATION This is Continuation-in-part of the U. S. patent application Ser. No. 71,309, filed on Sept. 11, l970, now abandoned.
The present invention relates to a parenteral solution bag, particularly to a parenteral solution bag improved in the mechanism for hermetically sealing the opening for taking in or out parenteral solution.
Parenteral solution bags are used for taking out blood or transfusion. A conventional hermetically sealing mechanism for this kind of bag is a rubber plug sealing in which the outlet opening is sealed with rubber plugs,. This type of sealing has many disadvantages: e.g., it is inconvenient to open the seal, the seal is easily polluted after it is opened, the outlet opening is easily polluted when opened, and sterilization of the rubber plug portion is difficult to effect.
The object of the present invention is to provide a parenteral solution bag having a simple sealing mechanism, not pollutable in the inlet and outlet of parenteral solution while hermetically sealed and when unsealed, and sterilizable as a whole under hermetically sealed condition such as in an autoclave, thus eliminating the above-mentioned drawbacks of conventional parenteral solution bags.
Another object of the invention is to provide a parenteral solution bag capable of having its tab peeled easily and reliably, being conveniently handled when opened and also being safely operated from a hygienic point of VI\V.
The attached drawings show an embodiment of the parenteral solution bag according to the present invention, in which:
FIG. 1 is a plan view of a parenteral solution bag according to the present invention;
FIG. 2 is a perspective view of the outlet of the parenteral solution bag;
FIG. 3 is a cross-sectional view taken along IIIIII line of FIG. 1;
FIGS. 4 to 6 are sectional views showing the process of heat sealing the tab to the protective closure;
FIG. 7 is a sectional view of the tab while it is peeled; and
FIGS. 8 to 12 are lateral views showing the sequential processes of exposing the outlet of the parenteral solution bag.
The present invention will be explained with reference to an embodiment illustrated .in the drawings.
The reference numeral 11 denotes a parenteral solution bag of a pliable and transparent plastic such as polyvinyl chloride which contains a proper quantity of ACD solution inside and the perimeter 11a of which is heat sealed. From a part of said perimeter 11a are derived a tubular extension 13 connected to a blood drawing needle 12 and a pair of solution ports 14. The numeral indicates a ball valve. Each port 14 is in the form of a hollow cylinder, one end being open to the inside of the bag 11 and the other end open to the outside of the bag 11. Between said two openings is stretched a diaphragm 15, through which a cannula can be pierced into the bag 11 and which prevents the outflow of the liquid existing inside bag 11. Further, protective closures l6 hermetically cover the whole ports 14 so as to prevent the pollution of the ports 14. Each protective closure 16 forms a bag and is provided with a tab 17 on one face. The base end portion 17a of the tab 17 is fused to the protruding front of said protective closure 16 and the other end portion 17b of said tab 17 is lapped over the surface of the protective closure 16 toward the end connected with the parenteral solution bag as a gripping means.
The seal 18 between the joined base portion 17a and the free end portion 17b of tab 17 is so arranged that is preferably placed over the port 14 and roughly V- shaped.
It is preferred for the reason given later that the end of the V-shaped seal be superposed, as shown in FIG. 1, on the near upper portion of the diaphragm.
What is important in heat sealing the tab 17 to the protective closure 16 is that the tab 17 be sealed sufficiently airtight to ensure complete sterilization and, when the protective closure is to be unsealed, be opened easily and reliably without being broken off. Therefore, this invention consists in, as illustrated in FIGS. 4 to 7, heat sealing the tab 17 to the protective closure 16 in the direction in which the latter is set in place and fusing together the sheets of both closure 16 and tab 17 to form a V-shaped groove extending into the tab 17. There will now be described the process of the invention by reference to these figures. There is first superposed the protective closure 16 on the tab I 17. Then a heater 20 is moved near the superposed assembly from the side of the protective closure 16 FIG. 4). The heater 20 is forced into the mass until its end reaches the tab 17 to fuse both sheets together (FIG. 5). When the heater 20 is taken off, there is obtained a V-shaped groove 18a, on both sides of which there are formed upward projecting ribs 18b. Another heater 21 is intended to ensure the full fusion of the tab 17 to the protective closure 16, thereby increasing the flexural strength of the tab 17 when it is peeled. As shown in FIGS. 4 and 5, the latter heater 21 is placed adjacent to the first mentioned heater 20 to produce both heat seals simultaneously. Since, however, the latter heater 21 is intended simply to ensure the tight fusion of the tab 17 to the protective closure 16, and also to form ribs 22 so as to elevate the flexural strength of the tab 17, the latter heater 21 need not be inserted into the superposed mass so deeply as the first mentioned heater 20.
When the tab 17 is thus heat sealed to the protective closure 16, the boundary (A) between the fused and nonfused portions of the protective closure 16 becomes slightly thinned, as shown in FIG. 7, and in consequence is reduced in tear strength, permitting its easy breakage when the tab 17 is pulled. Though, therefore, the sheets of both protective closure 16 and tab 17 originally had the same thickness, the protective closure 16 alone is sure to be broken, eliminating the necessity of making the sheet of the tab 17 thicker than that of the protective closure 16. This offers in manufacture the advantage of using plastic sheets of the same material and thickness in common to the protective closure 16 and tab 17. As the material for protective closure 16 and tab 17, a pliable and transparent film such as soft polyvinyl chloride film or polyolefin resin film may be used.
According to a preferred embodiment, the protective closure 16 has a thickness of a 0.4 mm and an inner width (Y) of about 16 mm as against the port 14 having a diameter (X) of about 7 mm, and the distance (Z) between the end of the port 14 and the inner end of the protective closure 16 is about 5 mm. The tab 17 consists of the same kind of plastic sheet as the protective closure 16, and is heat sealed thereto in advance by the process illustrated in FIGS. 4 to 6. As apparent from FlG. 2, the final heat seal pattern is such that the side of the base portion of the tab 17 which faces the parenteral solution bag 11 is formed into a pyramidic shape above the port 14 with the pointed top of said pyramidic shape disposed slightly above the diaphragm 15. When, as shown in FIG. 8, the port 14 is bent to peel off the tab 17 with its free end 17b gripped by hand, the boundary between the port 14 and diaphragm 15 is naturally bent, enabling said free end portion 17b to be easily gripped. There is further advantage that since the diaphragm 15 is difficult to bend, the tab 17 can be peel off, as illustrated in FIG. 9, without loss of the peeling force. The pyramidic heat sealed pattern is not limited to what is indicated, but any other similar pattern may be accepted, provided that it causes the peeling force to be concentrated at a point so as to permit the easy removal of the tab 17.
There will now be described the process of peeling off the tab 17. The free end portion 17b of the tab 17 is gripped by hand as shown in FIG. 8 so as to be taken off through the steps as illustrated in FIGS. 9 to 12. Since the tab 17 has its base portion 170 integrally formed with the protective closure 16 and there are formed a V-shaped groove 18a and ribs 18b in the heat sealed portion 18 of the superposed assembly of the protective closure 16 and tab 17, said heat sealed portion 18 is allowed to have a prominently greater flexural strength than the opposite side 16a of the protective closure 16. When, therefore, the tab 17 is pulled down by the finger as shown in FIG. 11, the tab 17 is not bent, but the protective closure 16 alone is bent. Further, the end 16b of the protective closure 16 is not provided with a V-shaped groove illustrated in FIGS. 4 to 6, but is fully heat sealed by the ordinary method used in fusing together laminated sheets. When, therefore, the tab 17 is peeled off, said end 16b of the protective closure 16 is not taken off together with the tab 17.
When the tab 17 is peeled, its base portion 17a is not bent and the end 16b of the protective closure 16 remains fused to the tab 17. Therefore, the protective closure 16 and tab 17jointly act as a spring to the finger when it presses the tab 17 from the inside, preventing the tab 17 from getting away from the finger. As shown in FlG. 12, therefore, the finger can be inserted fully into the protective closure 16 so as to easily expose the port 14. Accordingly, when there is inserted a cannula into the port 14, the tab 17 plays the part of holding the finger. Namely, the tab 17 not only serves to tear open the protective closure 16, but also acts as a stopper for preventing the finger from slipping.
It is also possible, as shown in FIGS. 1 to 6, to form a pair of heat sealed portions 19 having ribs 22 in the base portion 17a of the tab 17 for reinforcement to increase its stopper action. 7
The parenteral solution bag 11 provided with ports 14 having above-mentioned structure and arranged in the periphery of bag 11' is convenient to manufacture compared with the case in which ports are arranged in the bag face. The advantage of the present parenteral solution bag also lies in that there are further advantages that plastic sheets of the same material and thickness are used for both the protective closure and tab; the tab is unfailingly peeled off; the joint of the protective closure and the tab is easily broken by the peeling of the latter; the tab concurrently acts as a stopper when it is peeled; and the cannula is easily inserted. Further, parenteral solution may be taken out while the bag is suspended by means of a hanger hole 23. There is no possibility for hands to touch ports 14, and this is a merit from a hygienic point of view.
In connection with maintaining sterility. since the protective closure is peeled in such a way as illustrated in FIGS. 8 to 12, there is little possibility that germs sticked to the tab or protective closure fall into the port as the tab is turned over. This is one of the important advantages of the present invention over the known parenteral solution bags.
What is claimed is:
1. In a parenteral solution bag comprising at least one port tube protruding from part of the perimeter of the bag and hermetically enclosed by a bag-like protective closure, a diaphragm provided in the port tube sealing off the port tube from flow-off liquid within the bag through the port tube, and a tab peripherally heat sealed to a portion of said protective closure having an unsealed free end, the improvement which comprises in combination:
- a. the free end of the tab extending toward said bag,
1'). a V-shaped groove extending through said protective closure and into said tab, said tab and said closure being connected by a heat seal which extends along the periphery of said groove, and a pair of ribs on said closure, said ribs extending adjacent I said groove, 1 c. the apex of said V-shaped groove facing toward the junction of said port tube with said bag, d. said V-shaped groove being positioned over said I port tube and extending transversely to the port k tube, and i e. the heat sealed portion of said tab being more rigid l than the portion of said protective closure not sealed to said tab so that when the tab is peeled and turned backward towards the opposite side of said port tube, said heat sealed portion of said tab does not bend but instead said portion of said protective closure not sealed to said tube bends.
2. The parenteral solution bag of claim 1 wherein there is on said tab a pair of longitudinal heat seal portions accompanied with ribs spaced apart from one another and depending parallel to the longitudinal axis of said port tube from adjacent said V-shaped groove.
3. The parenteral solution bag of claim 1 wherein said protective closure is a rectangular shaped envelope formed of plastic sheet heat sealed along the two longest sides and one of the shorter sides, the other short side is heat sealed to said bag with said port tube enclosed by said protective closure and said V-shaped groove faces inward toward said port tube and extends from the heat seal along one of said longest sides to the heat seal along the other longest side.

Claims (3)

1. In a parenteral solution bag comprising at least one port tube protruding from part of the perimeter of the bag and hermetically enclosed by a bag-like protective closure, a diaphragm provided in the port tube sealing off the port tube from flow-off liquid within the bag through the port tube, and a tab peripherally heat sealed to a portion of said protective closure having an unsealed free end, the improvement which comprises in combination: a. the free end of the tab extending toward said bag, b. a V-shaped groove extending through said protective closure and into said tab, said tab and said closure being connected by a heat seal which extends along the periphery of said groove, and a pair of ribs on said closure, said ribs extending adjacent said groove, c. the apex of said V-shaped groove facing toward the junction of said port tube with said bag, d. said V-shaped groove being positioned over said port tube and extending transversely to the port tube, and e. the heat sealed portion of said tab being more rigid than the portion of said protective closure not sealed to said tab so that when the tab is peeled and turned backward towards the opposite side of said port tube, said heat sealed portion of said tab does not bend but instead said portion of said protective closure not sealed to said tube bends.
2. The parenteral solution bag of claim 1 wherein there is on said tab a pair of longitudinal heat seal portions accompanied with ribs spaced apart from one another and depending parallel to the longitudinal axis of said port tube from adjacent said V-shaped groove.
3. The parenteral solution bag of claim 1 wherein said protective closure is a rectangular shaped envelope formed of plastic sheet heat sealed along the two longest sides and one of the shorter sides, the other short side is heat sealed to said bag with said port tube enclosed by said protective closure and said V-shaped groove faces inward toward said port tube and extends from the heat seal along one of said longest sides to the heat seal along the other longest side.
US00220763A 1972-01-26 1972-01-26 Parenteral solution bag Expired - Lifetime US3788374A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22076372A 1972-01-26 1972-01-26

Publications (1)

Publication Number Publication Date
US3788374A true US3788374A (en) 1974-01-29

Family

ID=22824860

Family Applications (1)

Application Number Title Priority Date Filing Date
US00220763A Expired - Lifetime US3788374A (en) 1972-01-26 1972-01-26 Parenteral solution bag

Country Status (1)

Country Link
US (1) US3788374A (en)

Cited By (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3986507A (en) * 1975-04-16 1976-10-19 Inpaco Parenteral container
US3989045A (en) * 1972-09-29 1976-11-02 Eck William F Van Hypodermic syringe
US4006745A (en) * 1975-05-22 1977-02-08 Sorenson Research Co., Inc. Autologous transfusion system and method
US4119267A (en) * 1976-08-18 1978-10-10 Agis Frank Kydonieus Blood and intravenous solution bag
US4119128A (en) * 1977-02-18 1978-10-10 Marilyn Bishop Tamperproof sterile port cover and method of making same
US4126167A (en) * 1976-12-06 1978-11-21 Patient Care Products, Inc. Gastric tube drainage bag
US4131200A (en) * 1976-07-06 1978-12-26 Union Carbide Corporation Thermoplastic blood bag
US4183434A (en) * 1977-09-02 1980-01-15 Pharmachem Corporation Peelable seal
US4191231A (en) * 1977-07-22 1980-03-04 Baxter Travenol Laboratories, Inc. Flexible collapsible containers, and method of molding
US4198972A (en) * 1978-04-17 1980-04-22 Pharmachem Corporation Blood and blood component storage bags
US4226330A (en) * 1976-11-01 1980-10-07 Butler Robert W Rupture lines in flexible packages
US4228835A (en) * 1979-02-23 1980-10-21 Baxter Travenol Laboratories, Inc. Breakaway cap for solution containers
US4234026A (en) * 1979-03-05 1980-11-18 Baxter Travenol Laboratories, Inc. Seal for flexible container
US4294574A (en) * 1979-03-05 1981-10-13 Baxter Travenol Laboratories, Inc. Method of making seal for flexible container
US4305443A (en) * 1979-03-05 1981-12-15 Baxter Travenol Laboratories, Inc. Seal for flexible container having flexible, generally conical portions
US4316576A (en) * 1980-11-06 1982-02-23 Baxter Travenol Laboratories, Inc. Method and chamber for separating granulocytes from whole blood
US4340049A (en) * 1979-10-18 1982-07-20 Baxter Travenol Laboratories, Inc. Breakaway valve
USRE31135E (en) * 1977-07-22 1983-02-01 Baxter Travenol Laboratories, Inc. Flexible collapsible containers, and method of molding
WO1983001416A1 (en) * 1981-10-22 1983-04-28 Baxter Travenol Lab Frangible port protector
US4386622A (en) * 1979-10-18 1983-06-07 Baxter Travenol Laboratories, Inc. Breakaway valve
US4390104A (en) * 1981-08-19 1983-06-28 U.S. Clinical Products, Inc. Flexible plastic sterile closure system for containers
EP0096115A2 (en) * 1982-06-07 1983-12-21 U.S. Clinical Products, Inc. Flexible sterile closure system for containers
US4439192A (en) * 1975-05-30 1984-03-27 Stichting Centraal Laboratorium Van De Bloedtransfusiedienst Van Het Nederlandse Rode Kruis Container for liquids for use in medicine and surgery
US4460365A (en) * 1976-07-08 1984-07-17 Biotest-Serum Institute Gmbh Polyurethane bag for blood
GB2132985A (en) * 1983-01-08 1984-07-18 Boots Co Plc Container
US4484916A (en) * 1982-01-20 1984-11-27 American Hospital Supply Corporation Medical solution container and port construction
WO1985001268A1 (en) * 1983-09-15 1985-03-28 Baxter Travenol Laboratories, Inc. Compartment mixing container having breakable connection between compartments
US4598834A (en) * 1985-02-06 1986-07-08 U.S. Clinical Products, Inc. Flexible sterile closure system for a container with a side injection port
US4838429A (en) * 1986-10-10 1989-06-13 Baxter International Inc. Flexible thermoplastic pouches having easy-open tear strip means and apparatus for making same
US4917684A (en) * 1986-09-01 1990-04-17 Japan Medical Supply Co., Ltd. Protective cover for inlet/outlet ports of the plastic bag used for medical purpose
US5222950A (en) * 1990-07-16 1993-06-29 Eisenberg Melvin I Quick release tamper evident closure device
US6280431B1 (en) * 1998-10-23 2001-08-28 Abbott Laboratories Sterile formed, filled and sealed flexible container and draining administration port therefor
US6491679B1 (en) 1997-10-20 2002-12-10 Rodney Okamoto System for infusing intravenous nutrition solutions
US6578723B1 (en) 1997-05-30 2003-06-17 Pharmacy, Inc. Flexible sealing cover with seal break indicator
US20030146170A1 (en) * 2002-02-01 2003-08-07 Frank Corbin Whole blood collection and processing method
US6652942B2 (en) 2001-01-08 2003-11-25 Baxter International Inc. Assembly for a flowable material container
US6869653B2 (en) 2001-01-08 2005-03-22 Baxter International Inc. Port tube closure assembly
US20050138783A1 (en) * 2002-05-07 2005-06-30 Craig Emily A. Containment system
US20060036214A1 (en) * 2004-08-10 2006-02-16 Mogensen Lasse W Cannula device
US20070149934A1 (en) * 2003-02-27 2007-06-28 Brinks Hofer Gilson & Lione Disposable urine bag for collecting urine
US20080039794A1 (en) * 2004-03-20 2008-02-14 Grete Kornerup Injection Device for Infusion Set
US20080215003A1 (en) * 2005-03-17 2008-09-04 Grete Kornerup Gateway System
US20090076453A1 (en) * 2005-12-23 2009-03-19 Signe Thorning Mejlhede Device for Administration
US20090204077A1 (en) * 2008-02-13 2009-08-13 Hasted Soren B Moulded Connection Between Cannula and Delivery Part
US20090218243A1 (en) * 2006-02-13 2009-09-03 Unomedical A/S Packing for Injection Device
US20100004597A1 (en) * 2006-08-02 2010-01-07 Unomedical A/S Insertion Device
US20100022960A1 (en) * 2006-02-28 2010-01-28 Mejlhede Signe T Inserter for Infusion Part and Infusion Part Provided with Needle Protector
US20100030155A1 (en) * 2006-08-02 2010-02-04 Steffen Gyrn Cannula and Delivery Device
US20100063453A1 (en) * 2007-02-02 2010-03-11 Julie Grundtvig Theander Gateway Device
US20100137829A1 (en) * 2007-02-02 2010-06-03 Nielsen Henrik Boeje Injection Gateway
US20100140125A1 (en) * 2007-02-02 2010-06-10 Orla Mathiasen Injection Site for Injecting Medication
US20100152665A1 (en) * 2007-06-20 2010-06-17 Hasted Soeren Bo Cannula Insertion Device with Automatic Needle Retraction Comprising Only One Spring
US20100179508A1 (en) * 2005-06-28 2010-07-15 Unomedical A/S Packing for an infusion set and method of applying an infusion set
US20100198157A1 (en) * 2007-05-07 2010-08-05 Steffen Gyrn Cannula and Delivery Device
US20100228226A1 (en) * 2007-07-10 2010-09-09 Jens Egebjerg Nielsen Inserter Having Two Springs
US20100280498A1 (en) * 2007-06-20 2010-11-04 Jan Kent Olsen Catheter and a method and an apparatus for making such catheter
US20100286714A1 (en) * 2007-07-18 2010-11-11 Steffen Gyrn Inserter device with controlled acceleration
US20100286615A1 (en) * 2007-07-03 2010-11-11 Steffen Gyrn Inserter having bistable equilibrium states
US20100294693A1 (en) * 2009-05-22 2010-11-25 Fenwal, Inc. Containers and components thereof for use in the medical industry and methods to manufacture the same
US20110034883A1 (en) * 2008-02-13 2011-02-10 Steffen Gyrn Sealing Between a Cannula Part and a Fluid Path
US20110040263A1 (en) * 2008-02-08 2011-02-17 Unomedical A/S Inserter Assembly
US20110036844A1 (en) * 2008-02-25 2011-02-17 Unomedical A/S Bubble Shaped Membrane and Use of Such Membrane in a Device
US20110046456A1 (en) * 2008-02-08 2011-02-24 Hoerdum Elo Lau Assembly Comprising Inserter, Cannula Part and Base Part
US20110137257A1 (en) * 2008-07-07 2011-06-09 Unomedical A/S Inserter for Transcutaneous Device
US20110165367A1 (en) * 2008-09-10 2011-07-07 Panasonic Corporation Vacuum heat insulation material and manufacturing method therefor
US8012126B2 (en) 2006-10-31 2011-09-06 Unomedical A/S Infusion set
US20110226652A1 (en) * 2008-09-29 2011-09-22 Richard Morgan Hickmott Packing for Inserter
US20110290798A1 (en) * 2008-11-10 2011-12-01 Julie Corbett Thermoformed liquid-holding vessels
WO2012062395A3 (en) * 2010-11-08 2012-12-27 Sartorius Weighing Technology Gmbh Welding device, use thereof as a control valve, and metering device
US8439838B2 (en) 2006-06-07 2013-05-14 Unomedical A/S Inserter for transcutaneous sensor
US8562567B2 (en) 2009-07-30 2013-10-22 Unomedical A/S Inserter device with horizontal moving part
US8663419B2 (en) 2010-11-30 2014-03-04 Ecologic Manual container assembly and liner integration fixture for pulp-molded shell with polymer liner container systems
US8790311B2 (en) 2006-06-09 2014-07-29 Unomedical A/S Mounting pad
US9254373B2 (en) 2008-12-22 2016-02-09 Unomedical A/S Medical device comprising adhesive pad
USD751190S1 (en) * 2013-02-20 2016-03-08 Nipro Corporation Infusion bag
US9415159B2 (en) 2010-03-30 2016-08-16 Unomedical A/S Medical device
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US9533092B2 (en) 2009-08-07 2017-01-03 Unomedical A/S Base part for a medication delivery device
US9566384B2 (en) 2008-02-20 2017-02-14 Unomedical A/S Insertion device with horizontally moving part
US9668909B1 (en) * 2011-02-27 2017-06-06 Ann M. Lormand-Koch Method of using gastrojejunostomy drainage bag
US9724127B2 (en) 2010-09-27 2017-08-08 Unomedical A/S Insertion system and insertion kit
US10369277B2 (en) 2005-09-12 2019-08-06 Unomedical A/S Invisible needle
US11020526B2 (en) 2010-10-04 2021-06-01 Unomedical A/S Sprinkler cannula
US11110261B2 (en) 2011-10-19 2021-09-07 Unomedical A/S Infusion tube system and method for manufacture
US11197689B2 (en) 2011-10-05 2021-12-14 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3110308A (en) * 1960-10-20 1963-11-12 Baxter Laboratories Inc Parenteral fluid administration equiment
US3339825A (en) * 1965-12-08 1967-09-05 Doughboy Ind Inc Bag
US3343541A (en) * 1964-01-08 1967-09-26 Baxter Laboratories Inc Parenteral container
US3426959A (en) * 1967-01-16 1969-02-11 Jerome H Lemelson Packaging assembly

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3110308A (en) * 1960-10-20 1963-11-12 Baxter Laboratories Inc Parenteral fluid administration equiment
US3343541A (en) * 1964-01-08 1967-09-26 Baxter Laboratories Inc Parenteral container
US3339825A (en) * 1965-12-08 1967-09-05 Doughboy Ind Inc Bag
US3426959A (en) * 1967-01-16 1969-02-11 Jerome H Lemelson Packaging assembly

Cited By (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3989045A (en) * 1972-09-29 1976-11-02 Eck William F Van Hypodermic syringe
US3986507A (en) * 1975-04-16 1976-10-19 Inpaco Parenteral container
US4006745A (en) * 1975-05-22 1977-02-08 Sorenson Research Co., Inc. Autologous transfusion system and method
US4439192A (en) * 1975-05-30 1984-03-27 Stichting Centraal Laboratorium Van De Bloedtransfusiedienst Van Het Nederlandse Rode Kruis Container for liquids for use in medicine and surgery
US4496362A (en) * 1975-05-30 1985-01-29 Stichtig Centraal Laboratorium Van De Bloedtrasfusiedienst Van Het Nederlandse Rode Kruis Container for liquids for use in medicine and surgery
US4131200A (en) * 1976-07-06 1978-12-26 Union Carbide Corporation Thermoplastic blood bag
US4460365A (en) * 1976-07-08 1984-07-17 Biotest-Serum Institute Gmbh Polyurethane bag for blood
US4119267A (en) * 1976-08-18 1978-10-10 Agis Frank Kydonieus Blood and intravenous solution bag
US4226330A (en) * 1976-11-01 1980-10-07 Butler Robert W Rupture lines in flexible packages
US4126167A (en) * 1976-12-06 1978-11-21 Patient Care Products, Inc. Gastric tube drainage bag
US4119128A (en) * 1977-02-18 1978-10-10 Marilyn Bishop Tamperproof sterile port cover and method of making same
US4191231A (en) * 1977-07-22 1980-03-04 Baxter Travenol Laboratories, Inc. Flexible collapsible containers, and method of molding
USRE31135E (en) * 1977-07-22 1983-02-01 Baxter Travenol Laboratories, Inc. Flexible collapsible containers, and method of molding
US4183434A (en) * 1977-09-02 1980-01-15 Pharmachem Corporation Peelable seal
US4198972A (en) * 1978-04-17 1980-04-22 Pharmachem Corporation Blood and blood component storage bags
US4228835A (en) * 1979-02-23 1980-10-21 Baxter Travenol Laboratories, Inc. Breakaway cap for solution containers
US4294574A (en) * 1979-03-05 1981-10-13 Baxter Travenol Laboratories, Inc. Method of making seal for flexible container
US4305443A (en) * 1979-03-05 1981-12-15 Baxter Travenol Laboratories, Inc. Seal for flexible container having flexible, generally conical portions
US4234026A (en) * 1979-03-05 1980-11-18 Baxter Travenol Laboratories, Inc. Seal for flexible container
US4340049A (en) * 1979-10-18 1982-07-20 Baxter Travenol Laboratories, Inc. Breakaway valve
US4386622A (en) * 1979-10-18 1983-06-07 Baxter Travenol Laboratories, Inc. Breakaway valve
US4316576A (en) * 1980-11-06 1982-02-23 Baxter Travenol Laboratories, Inc. Method and chamber for separating granulocytes from whole blood
WO1982001480A1 (en) * 1980-11-06 1982-05-13 Baxter Travenol Lab Method and chamber for separating granulocytes from whole blood
US4390104A (en) * 1981-08-19 1983-06-28 U.S. Clinical Products, Inc. Flexible plastic sterile closure system for containers
US4415393A (en) * 1981-10-22 1983-11-15 Baxter Travenol Laboratories, Inc. Method of making a frangible port protector
WO1983001416A1 (en) * 1981-10-22 1983-04-28 Baxter Travenol Lab Frangible port protector
US4484916A (en) * 1982-01-20 1984-11-27 American Hospital Supply Corporation Medical solution container and port construction
EP0096115A2 (en) * 1982-06-07 1983-12-21 U.S. Clinical Products, Inc. Flexible sterile closure system for containers
EP0096115A3 (en) * 1982-06-07 1984-08-22 U.S. Clinical Products, Inc. Flexible sterile closure system for containers
US4527703A (en) * 1982-06-07 1985-07-09 U.S. Clinical Products, Inc. Flexible sterile closure system for containers
GB2132985A (en) * 1983-01-08 1984-07-18 Boots Co Plc Container
US4596573A (en) * 1983-01-08 1986-06-24 The Boots Company P.L.C. Container
US4770295A (en) * 1983-09-15 1988-09-13 Baxter Travenol Laboratories, Inc. Selectively openable seal line and containers having same
WO1985001268A1 (en) * 1983-09-15 1985-03-28 Baxter Travenol Laboratories, Inc. Compartment mixing container having breakable connection between compartments
US4598834A (en) * 1985-02-06 1986-07-08 U.S. Clinical Products, Inc. Flexible sterile closure system for a container with a side injection port
US4917684A (en) * 1986-09-01 1990-04-17 Japan Medical Supply Co., Ltd. Protective cover for inlet/outlet ports of the plastic bag used for medical purpose
US4838429A (en) * 1986-10-10 1989-06-13 Baxter International Inc. Flexible thermoplastic pouches having easy-open tear strip means and apparatus for making same
US5222950A (en) * 1990-07-16 1993-06-29 Eisenberg Melvin I Quick release tamper evident closure device
US6578723B1 (en) 1997-05-30 2003-06-17 Pharmacy, Inc. Flexible sealing cover with seal break indicator
US6491679B1 (en) 1997-10-20 2002-12-10 Rodney Okamoto System for infusing intravenous nutrition solutions
US6280431B1 (en) * 1998-10-23 2001-08-28 Abbott Laboratories Sterile formed, filled and sealed flexible container and draining administration port therefor
US20040086675A1 (en) * 2001-01-08 2004-05-06 Ling Michael T.K. Assembly for a flowable material container
US6652942B2 (en) 2001-01-08 2003-11-25 Baxter International Inc. Assembly for a flowable material container
US7329445B2 (en) 2001-01-08 2008-02-12 Baxter International Inc. Assembly for a flowable material container
US6869653B2 (en) 2001-01-08 2005-03-22 Baxter International Inc. Port tube closure assembly
US20050158499A1 (en) * 2001-01-08 2005-07-21 Ling Michael T. Port tube and closure composition, structure and assembly for a flowale material container
US7550185B2 (en) 2001-01-08 2009-06-23 Baxter International Inc. Port tube and closure composition, structure and assembly for a flowable material container
US20050274673A1 (en) * 2002-02-01 2005-12-15 Gambro, Inc Whole blood collection and processing method
US6994790B2 (en) 2002-02-01 2006-02-07 Gambro, Inc. Whole blood collection and processing method
US20030146170A1 (en) * 2002-02-01 2003-08-07 Frank Corbin Whole blood collection and processing method
US20050138783A1 (en) * 2002-05-07 2005-06-30 Craig Emily A. Containment system
US7228603B2 (en) 2002-05-07 2007-06-12 Bluegrass Bio, Inc. Containment system
US20070149934A1 (en) * 2003-02-27 2007-06-28 Brinks Hofer Gilson & Lione Disposable urine bag for collecting urine
US8282613B2 (en) * 2003-02-27 2012-10-09 Unomedical A/S Disposable urine bag for collecting urine
US20080039794A1 (en) * 2004-03-20 2008-02-14 Grete Kornerup Injection Device for Infusion Set
US8287516B2 (en) 2004-03-26 2012-10-16 Unomedical A/S Infusion set
US8221355B2 (en) 2004-03-26 2012-07-17 Unomedical A/S Injection device for infusion set
US20060036214A1 (en) * 2004-08-10 2006-02-16 Mogensen Lasse W Cannula device
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
US20080215003A1 (en) * 2005-03-17 2008-09-04 Grete Kornerup Gateway System
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
US20100179508A1 (en) * 2005-06-28 2010-07-15 Unomedical A/S Packing for an infusion set and method of applying an infusion set
US10369277B2 (en) 2005-09-12 2019-08-06 Unomedical A/S Invisible needle
US8303549B2 (en) 2005-12-23 2012-11-06 Unomedical A/S Injection device
US9278173B2 (en) 2005-12-23 2016-03-08 Unomedical A/S Device for administration
US20090221971A1 (en) * 2005-12-23 2009-09-03 Signe Thorning Mejlhede Injection device
US20090076453A1 (en) * 2005-12-23 2009-03-19 Signe Thorning Mejlhede Device for Administration
US20090218243A1 (en) * 2006-02-13 2009-09-03 Unomedical A/S Packing for Injection Device
US20100022960A1 (en) * 2006-02-28 2010-01-28 Mejlhede Signe T Inserter for Infusion Part and Infusion Part Provided with Needle Protector
US9211379B2 (en) 2006-02-28 2015-12-15 Unomedical A/S Inserter for infusion part and infusion part provided with needle protector
US8439838B2 (en) 2006-06-07 2013-05-14 Unomedical A/S Inserter for transcutaneous sensor
US8790311B2 (en) 2006-06-09 2014-07-29 Unomedical A/S Mounting pad
US20100030155A1 (en) * 2006-08-02 2010-02-04 Steffen Gyrn Cannula and Delivery Device
US8945057B2 (en) 2006-08-02 2015-02-03 Unomedical A/S Cannula and delivery device
US20100004597A1 (en) * 2006-08-02 2010-01-07 Unomedical A/S Insertion Device
US8012126B2 (en) 2006-10-31 2011-09-06 Unomedical A/S Infusion set
US20100063453A1 (en) * 2007-02-02 2010-03-11 Julie Grundtvig Theander Gateway Device
US20100137829A1 (en) * 2007-02-02 2010-06-03 Nielsen Henrik Boeje Injection Gateway
US20100140125A1 (en) * 2007-02-02 2010-06-10 Orla Mathiasen Injection Site for Injecting Medication
US20100198157A1 (en) * 2007-05-07 2010-08-05 Steffen Gyrn Cannula and Delivery Device
US9186480B2 (en) 2007-06-20 2015-11-17 Unomedical A/S Apparatus for making a catheter
US20100152665A1 (en) * 2007-06-20 2010-06-17 Hasted Soeren Bo Cannula Insertion Device with Automatic Needle Retraction Comprising Only One Spring
US9320869B2 (en) 2007-06-20 2016-04-26 Unomedical A/S Apparatus for making a catheter
US20100280498A1 (en) * 2007-06-20 2010-11-04 Jan Kent Olsen Catheter and a method and an apparatus for making such catheter
US8430850B2 (en) 2007-07-03 2013-04-30 Unomedical A/S Inserter having bistable equilibrium states
US20100286615A1 (en) * 2007-07-03 2010-11-11 Steffen Gyrn Inserter having bistable equilibrium states
US20100228226A1 (en) * 2007-07-10 2010-09-09 Jens Egebjerg Nielsen Inserter Having Two Springs
US8486003B2 (en) 2007-07-10 2013-07-16 Unomedical A/S Inserter having two springs
US20100286714A1 (en) * 2007-07-18 2010-11-11 Steffen Gyrn Inserter device with controlled acceleration
US20110046456A1 (en) * 2008-02-08 2011-02-24 Hoerdum Elo Lau Assembly Comprising Inserter, Cannula Part and Base Part
US20110040263A1 (en) * 2008-02-08 2011-02-17 Unomedical A/S Inserter Assembly
US20090204077A1 (en) * 2008-02-13 2009-08-13 Hasted Soren B Moulded Connection Between Cannula and Delivery Part
US20110034883A1 (en) * 2008-02-13 2011-02-10 Steffen Gyrn Sealing Between a Cannula Part and a Fluid Path
US10898643B2 (en) 2008-02-13 2021-01-26 Unomedical A/S Sealing between a cannula part and a fluid path
US10376637B2 (en) 2008-02-20 2019-08-13 Unomedical A/S Insertion device with horizontally moving part
US9566384B2 (en) 2008-02-20 2017-02-14 Unomedical A/S Insertion device with horizontally moving part
US20110036844A1 (en) * 2008-02-25 2011-02-17 Unomedical A/S Bubble Shaped Membrane and Use of Such Membrane in a Device
US20110137257A1 (en) * 2008-07-07 2011-06-09 Unomedical A/S Inserter for Transcutaneous Device
US20110165367A1 (en) * 2008-09-10 2011-07-07 Panasonic Corporation Vacuum heat insulation material and manufacturing method therefor
US9103114B2 (en) * 2008-09-10 2015-08-11 Panasonic Corporation Vacuum heat insulation material and manufacturing method therefor
US20110226652A1 (en) * 2008-09-29 2011-09-22 Richard Morgan Hickmott Packing for Inserter
US20110290798A1 (en) * 2008-11-10 2011-12-01 Julie Corbett Thermoformed liquid-holding vessels
US9254373B2 (en) 2008-12-22 2016-02-09 Unomedical A/S Medical device comprising adhesive pad
US8622213B2 (en) 2009-05-22 2014-01-07 Fenwal, Inc. Containers and components thereof for use in the medical industry and methods to manufacture the same
US9539174B2 (en) 2009-05-22 2017-01-10 Fenwal, Inc. Containers and components thereof for use in the medical industry and methods to manufacture the same
US20100294693A1 (en) * 2009-05-22 2010-11-25 Fenwal, Inc. Containers and components thereof for use in the medical industry and methods to manufacture the same
US8562567B2 (en) 2009-07-30 2013-10-22 Unomedical A/S Inserter device with horizontal moving part
US9533092B2 (en) 2009-08-07 2017-01-03 Unomedical A/S Base part for a medication delivery device
US11786653B2 (en) 2010-03-30 2023-10-17 Unomedical A/S Insertion device
US9415159B2 (en) 2010-03-30 2016-08-16 Unomedical A/S Medical device
US9724127B2 (en) 2010-09-27 2017-08-08 Unomedical A/S Insertion system and insertion kit
US11020526B2 (en) 2010-10-04 2021-06-01 Unomedical A/S Sprinkler cannula
US9550588B2 (en) 2010-11-08 2017-01-24 Sartorius Lab Instruments Gmbh & Co. Kg Welding device, use thereof as a control valve, and metering device
WO2012062395A3 (en) * 2010-11-08 2012-12-27 Sartorius Weighing Technology Gmbh Welding device, use thereof as a control valve, and metering device
US8663419B2 (en) 2010-11-30 2014-03-04 Ecologic Manual container assembly and liner integration fixture for pulp-molded shell with polymer liner container systems
US9126719B2 (en) 2010-11-30 2015-09-08 Ecologic Manual container assembly and liner integration fixture for pulp-molded shell with polymer liner container systems
US9668909B1 (en) * 2011-02-27 2017-06-06 Ann M. Lormand-Koch Method of using gastrojejunostomy drainage bag
US11197689B2 (en) 2011-10-05 2021-12-14 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts
US11110261B2 (en) 2011-10-19 2021-09-07 Unomedical A/S Infusion tube system and method for manufacture
US11684767B2 (en) 2011-10-19 2023-06-27 Unomedical A/S Infusion tube system and method for manufacture
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
USD751190S1 (en) * 2013-02-20 2016-03-08 Nipro Corporation Infusion bag

Similar Documents

Publication Publication Date Title
US3788374A (en) Parenteral solution bag
US3986507A (en) Parenteral container
CA1120898A (en) Plastic container for medical liquid
US3255923A (en) Disposable liquid storage and dispensing device
US5088994A (en) Drip-feed bag and method for manufacturing same
US2704075A (en) Flexible plastic container
US3734154A (en) Disposable bag with self-closing valve
KR100994113B1 (en) A hermetically closed fluid bag with an integrally welded drinking spout or dispensing spout
WO1994026231A1 (en) Disposable bottle bags for use with infant nursing systems
US4909413A (en) Method of and apparatus for dispensing rubber gloves in an aseptic condition for insertion of the hands of a user
US3334764A (en) Infant nurser
JPH0510945B2 (en)
US3978859A (en) Closure member for pierceable access ports
US3910272A (en) Cannula for introducing a flexible catheter
US3228444A (en) Specimen container
JPH076182U (en) Wet paper packaging bag
YU131383A (en) Injection opening for plastic bags
JPH0411711Y2 (en)
EP0075576B1 (en) Sealing device for bag-shaped liquid-containers for sick-care
CN215437688U (en) Primary and secondary bag for pathological specimen
CN216985703U (en) Animal medicine infusion lid and infusion container
KR900007570Y1 (en) A device for a cap of intravacular drug container
JPH0872900A (en) Hermetically-sealed container comprised of synthetic resin film
JPH027573Y2 (en)
JPS6125794Y2 (en)