US5843379A - Sampling device for a chemical analysis apparatus - Google Patents

Sampling device for a chemical analysis apparatus Download PDF

Info

Publication number
US5843379A
US5843379A US08/809,207 US80920797A US5843379A US 5843379 A US5843379 A US 5843379A US 80920797 A US80920797 A US 80920797A US 5843379 A US5843379 A US 5843379A
Authority
US
United States
Prior art keywords
diaphragm
membrane
carrier
groove
surface layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
US08/809,207
Inventor
Steen Gaardsted Kristensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danfoss AS
Original Assignee
Danfoss AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danfoss AS filed Critical Danfoss AS
Assigned to DANFOSS A/S reassignment DANFOSS A/S ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KRISTENSEN, STEEN GAARDSTED
Application granted granted Critical
Publication of US5843379A publication Critical patent/US5843379A/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D63/00Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08Flat membrane modules
    • B01D63/087Single membrane modules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/18Apparatus therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24Dialysis ; Membrane extraction
    • B01D61/28Apparatus therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34Purifying; Cleaning
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00783Laminate assemblies, i.e. the reactor comprising a stack of plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00819Materials of construction
    • B01J2219/00822Metal
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00819Materials of construction
    • B01J2219/00824Ceramic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00819Materials of construction
    • B01J2219/00844Comprising porous material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00905Separation
    • B01J2219/00907Separation using membranes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4005Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25625Dilution
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Definitions

  • This invention refers to a sampling device for a chemical analysis apparatus, which device comprises a diaphragm attached to a diaphragm carrier, which has an inlet channel to the side of the diaphragm facing the carrier and a discharge channel going therefrom, which channels conduct the medium to be measured.
  • the medium absorbs ions, molecules or particles, which penetrate the diaphragm.
  • AT 355 546 discloses a known dialysis system of the kind mentioned in the introduction.
  • the dialysis diaphragm is attached to the outside of a curved diaphragm carrier.
  • a number of grooves forming channels are provided in the upper side of the diaphragm carrier.
  • FR A 1 573 147 shows a similar device, however with a plane diaphragm carrier.
  • a medium to be measured flows through the channels and ions from the surrounding medium penetrate the dialysis diaphragm into the medium to be measured, which is then sent to a chemical analysis apparatus.
  • JP A 59 170 742 it is known to mount a plate in which the channels are arranged.
  • the object of the invention according to this application is to provide a sampling device, which has a short reaction time and makes use of small amounts of medium to be measured.
  • the sampling device forms a small sample volume under the diaphragm where the sample volume has a large exposable upper surface facing the diaphragm.
  • the depth of the groove or the channel is determined in a special way and this means that this parameter is easy to determine.
  • the width of the groove can be determined exactly during the production.
  • the adhesive required to attach the diaphragm to the diaphragm carrier is at the same time used for forming the groove, which conducts the medium to be measured.
  • the adhesive may be applied to the diaphragm carrier or to the diaphragm in such a way that areas are formed, which are kept free from adhesive and these areas are in connection with each other so that an open path is formed.
  • the surface made as a layer of adhesive can alternatively be arranged between two layers of tape. This makes it possible to work the surface layer by water jet cutting or by punching in the same way as it is possible to form a groove in an adhesive double layer of tape.
  • the groove is formed in a surface layer e.g. a metal sheet and the groove is thus formed by punching, laser cutting, water jet cutting or etching of the metal layer.
  • the metal sheet or a sheet of a different material can be applied to the diaphragm carrier by means of an adhesive or the diaphragm can be clamped on the metal sheet and retained by the outside of the diaphragm carrier.
  • the sheet is made of plastic the groove or grooves can be formed by punching or by water jet cutting. Laser cutting may also be possible.
  • the sheet is made from double-sided adhesive tape.
  • a simple attachment to the diaphragm carrier and a correspondingly simple attachment of the diaphragm to the upper side of the sheet is hereby achieved.
  • the double-sided adhesive tape may have a protecting tape over the layer of adhesive during production and a groove can then advantageously be formed by water jet cutting, which gives a high degree of freedom in forming the groove.
  • diaphragms Different types are used for different purposes. Thus, it is possible to use the diaphragm as a filter or different pressures can be used on the sides of the diaphragm for a reversed osmosis.
  • the diaphragms may as well be used without a pressure difference for dialysis where ions penetrate the diaphragm and an equalization of the concentration of ions takes place on both sides of the diaphragm.
  • the sampling device according to the invention can be used in chemical analysis apparatuses, which are used for medical measurements.
  • the sampling device is also applicable for measuring in the production in chemical industries.
  • the invention can also be used when measuring the concentration of ions in waste water.
  • the drawing shows a diaphragm 1, and its characteristics determine the size or the chemical composition of particles, molecules or ions, which can penetrate the diaphragm.
  • a sheet 2 a groove 4 is arranged under the diaphragm 1.
  • the sheet can be made from metal, plastic or adhesive and the groove can be produced by punching, etching, laser cutting or water jet cutting.
  • the groove is shown in a certain zigzag pattern but the extension of the groove may be varied depending on the wanted length of the groove, the size of the areas etc.
  • a diaphragm carrier 3 is shown under the sheet 2 in the FIGURE.
  • the diaphragm carrier has an inlet channel 5 and a discharge channel 5'.
  • the channels 5 and 5' are connected with each one end of the groove 4. This forms a flow path from the outside to the inlet channel 5, through the groove 4 and out through the discharge channel 5'.
  • the diaphragm 1, the sheet 2 and the diaphragm carrier 3 are glued together.
  • the adhesive is applied on the sheet 2 before the groove 4 is formed, thus securing that the groove is free from adhesive.
  • the sheet 2 may be a double-sided adhesive tape or adhesive, by which the adhesive surfaces are covered by a protecting tape during production.
  • groove 4 may have different configurations depending on the application in question. There may also be several different grooves 4 under the same diaphragm and in connection with the inlet channel 5 and the discharge channel 5'.

Abstract

A sampling means of a chemical analysis apparatus includes a membrane, which is attached to a membrane carrier, which has an inlet passage to the side of the carrier facing the membrane and a discharge passage going therefrom. The passages conduct the medium to be measured and which medium absorbs ions, molecules or particles which pierce the membrane. In order to provide a sampling means, which has a short reaction time and makes use of small amounts of the medium to be measured and is easy to manufacture, the mouths of the inlet passage and of the discharge passage, which opens to the membrane, are interconnected by means of at least one groove, which is open towards the membrane. The groove is formed in a surface layer, which is attached between the membrane and the membrane carrier or is manufactured on the surface of the membrane carrier. The open side of the groove is closed by the membrane such that the membrane adheres to the surface layer or to the surface of the carrier facing the membrane.

Description

This application is a 371 of PCT/DK95/00354 filed on Sep. 4, 1995.
BACKGROUND OF THE INVENTION
This invention refers to a sampling device for a chemical analysis apparatus, which device comprises a diaphragm attached to a diaphragm carrier, which has an inlet channel to the side of the diaphragm facing the carrier and a discharge channel going therefrom, which channels conduct the medium to be measured. The medium absorbs ions, molecules or particles, which penetrate the diaphragm.
AT 355 546 discloses a known dialysis system of the kind mentioned in the introduction. For this purpose, the dialysis diaphragm is attached to the outside of a curved diaphragm carrier. A number of grooves forming channels are provided in the upper side of the diaphragm carrier. FR A 1 573 147 shows a similar device, however with a plane diaphragm carrier. A medium to be measured flows through the channels and ions from the surrounding medium penetrate the dialysis diaphragm into the medium to be measured, which is then sent to a chemical analysis apparatus. Through JP A 59 170 742 it is known to mount a plate in which the channels are arranged.
SUMMARY OF THE INVENTION
The object of the invention according to this application is to provide a sampling device, which has a short reaction time and makes use of small amounts of medium to be measured.
The sampling device according to the invention forms a small sample volume under the diaphragm where the sample volume has a large exposable upper surface facing the diaphragm. Thus, according to the invention, the depth of the groove or the channel is determined in a special way and this means that this parameter is easy to determine. Also the width of the groove can be determined exactly during the production.
The adhesive required to attach the diaphragm to the diaphragm carrier is at the same time used for forming the groove, which conducts the medium to be measured. The adhesive may be applied to the diaphragm carrier or to the diaphragm in such a way that areas are formed, which are kept free from adhesive and these areas are in connection with each other so that an open path is formed. The surface made as a layer of adhesive can alternatively be arranged between two layers of tape. This makes it possible to work the surface layer by water jet cutting or by punching in the same way as it is possible to form a groove in an adhesive double layer of tape.
In an embodiment the groove is formed in a surface layer e.g. a metal sheet and the groove is thus formed by punching, laser cutting, water jet cutting or etching of the metal layer.
The metal sheet or a sheet of a different material can be applied to the diaphragm carrier by means of an adhesive or the diaphragm can be clamped on the metal sheet and retained by the outside of the diaphragm carrier. This means that the sampling device can be made simply and cheaply. If the sheet is made of plastic the groove or grooves can be formed by punching or by water jet cutting. Laser cutting may also be possible. By using plastic for the sheet it is avoided that the metal emits ions to the medium to be measured, which a metal might do and if so the measurement would be deteriorated or destroyed in certain applications.
It is further suggested that the sheet is made from double-sided adhesive tape. A simple attachment to the diaphragm carrier and a correspondingly simple attachment of the diaphragm to the upper side of the sheet is hereby achieved. The double-sided adhesive tape may have a protecting tape over the layer of adhesive during production and a groove can then advantageously be formed by water jet cutting, which gives a high degree of freedom in forming the groove.
When the groove is formed in the sheet by etching there is also a large freedom concerning the shape of the groove.
Different types of diaphragms are used for different purposes. Thus, it is possible to use the diaphragm as a filter or different pressures can be used on the sides of the diaphragm for a reversed osmosis. The diaphragms may as well be used without a pressure difference for dialysis where ions penetrate the diaphragm and an equalization of the concentration of ions takes place on both sides of the diaphragm.
Advantageously, the sampling device according to the invention can be used in chemical analysis apparatuses, which are used for medical measurements. The sampling device is also applicable for measuring in the production in chemical industries. The invention can also be used when measuring the concentration of ions in waste water.
BRIEF DESCRIPTION OF THE DRAWING
A preferred embodiment of the invention among several ones will be described in the following with reference to enclosed drawing.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
The drawing shows a diaphragm 1, and its characteristics determine the size or the chemical composition of particles, molecules or ions, which can penetrate the diaphragm. A sheet 2 a groove 4 is arranged under the diaphragm 1. In this case the sheet can be made from metal, plastic or adhesive and the groove can be produced by punching, etching, laser cutting or water jet cutting. The groove is shown in a certain zigzag pattern but the extension of the groove may be varied depending on the wanted length of the groove, the size of the areas etc. A diaphragm carrier 3 is shown under the sheet 2 in the FIGURE. The diaphragm carrier has an inlet channel 5 and a discharge channel 5'. The channels 5 and 5' are connected with each one end of the groove 4. This forms a flow path from the outside to the inlet channel 5, through the groove 4 and out through the discharge channel 5'.
Advantageously, the diaphragm 1, the sheet 2 and the diaphragm carrier 3 are glued together. The adhesive is applied on the sheet 2 before the groove 4 is formed, thus securing that the groove is free from adhesive. As mentioned, the sheet 2 may be a double-sided adhesive tape or adhesive, by which the adhesive surfaces are covered by a protecting tape during production.
As mentioned above the groove 4 may have different configurations depending on the application in question. There may also be several different grooves 4 under the same diaphragm and in connection with the inlet channel 5 and the discharge channel 5'.

Claims (8)

I claim:
1. Sampling device for a chemical analysis apparatus for a medium, which device comprises a diaphragm attached to a diaphragm carrier, the device having an inlet channel on a side of a diaphragm facing the carrier and a discharge channel extending from the side of the diaphragm facing the carrier, which channels conduct the medium to be measured, and which medium absorbs ions, molecules or particles penetrating the diaphragm, by which openings of the inlet channel and of the discharge channel which open to the diaphragm are interconnected by means of at least one groove having an open side towards the diaphragm, the groove being formed in a surface layer which is located between the diaphragm and the diaphragm carrier, the open side of the groove being closed by the diaphragm and the diaphragm adhering to the surface layer.
2. Device according to claim 1, in which the diaphragm, the surface layer and the carrier have plane surfaces bearing against each other.
3. Device according to claim 2, in which the surface layer consists of an adhesive, in which at least one said groove is formed.
4. Device according to claim 1, in which the surface layer consists of a sheet.
5. Device according to claim 4, in which the sheet is made of metal.
6. Device according to claim 4, in which the sheet is made of plastic.
7. Device according to claim 4, in which the sheet is covered by an adhesive material on both sides.
8. Device according to claim 1, in which the surface layer consists of a fluid lining, which is applied on the carrier and which is hardened and adheres to the carrier.
US08/809,207 1994-09-07 1995-09-04 Sampling device for a chemical analysis apparatus Expired - Fee Related US5843379A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9402980A SE504779C2 (en) 1994-09-07 1994-09-07 Sampling device with membrane and membrane holder
SE9402980 1994-09-07
PCT/DK1995/000354 WO1996007885A1 (en) 1994-09-07 1995-09-04 Sampling means for a chemical analysis apparatus

Publications (1)

Publication Number Publication Date
US5843379A true US5843379A (en) 1998-12-01

Family

ID=20395154

Family Applications (1)

Application Number Title Priority Date Filing Date
US08/809,207 Expired - Fee Related US5843379A (en) 1994-09-07 1995-09-04 Sampling device for a chemical analysis apparatus

Country Status (5)

Country Link
US (1) US5843379A (en)
EP (1) EP0779974A1 (en)
AU (1) AU689637B2 (en)
SE (1) SE504779C2 (en)
WO (1) WO1996007885A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7736328B2 (en) 2007-07-05 2010-06-15 Baxter International Inc. Dialysis system having supply container autoconnection
US20110154918A1 (en) * 2009-12-30 2011-06-30 Syage Jack A Surface sampling mobile chemical detection probe
US8157761B2 (en) 2007-07-05 2012-04-17 Baxter International Inc. Peritoneal dialysis patient connection system
US8197087B2 (en) 2007-07-05 2012-06-12 Baxter International Inc. Peritoneal dialysis patient connection system using ultraviolet light emitting diodes
US8764702B2 (en) 2007-07-05 2014-07-01 Baxter International Inc. Dialysis system having dual patient line connection and prime
US9044544B2 (en) 2008-11-21 2015-06-02 Baxter International Inc. Dialysis machine having auto-connection system with roller occluder
US9586003B2 (en) 2007-07-05 2017-03-07 Baxter International Inc. Medical fluid machine with supply autoconnection
US10293091B2 (en) 2007-07-05 2019-05-21 Baxter International Inc. Dialysis system having an autoconnection mechanism

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19710525C2 (en) * 1997-03-14 1999-11-11 Cammann Karl Passive diffusion collector for analytes contained in gases as well as methods for passive sampling and analysis
DE19848542C2 (en) 1998-10-22 2001-07-05 Trace Biotech Ag Sampling probe
DE19919608A1 (en) 1999-05-27 2000-11-30 Roche Diagnostics Gmbh Sample holder for the IR spectroscopy of sample liquids
US7111503B2 (en) 2004-01-22 2006-09-26 Datalog Technology Inc. Sheet-form membrane sample probe, method and apparatus for fluid concentration analysis
US7569099B2 (en) 2006-01-18 2009-08-04 United Technologies Corporation Fuel deoxygenation system with non-metallic fuel plate assembly

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981000911A1 (en) * 1979-09-19 1981-04-02 Charles Hospital Dev Continuous flow automatic chemical analysis systems and components for use therein
US4366051A (en) * 1976-11-19 1982-12-28 Halbert Fischel Hemodialysis system
US4432806A (en) * 1981-01-14 1984-02-21 Aktieselskabet De Danske Sukkerfabrikker Method of purifying sugar juice prepared by extraction of a sugar beet material
EP0107631A2 (en) * 1982-09-28 1984-05-02 Bifok Ab Integrated microconduits for continuous flow analysis
US4503333A (en) * 1981-06-05 1985-03-05 Baxter Travenol Laboratories Antimicrobial ultraviolet irradiation of connector for continuous ambulatory peritoneal dialysis
US4552552A (en) * 1982-02-16 1985-11-12 Fresenius Ag Pump system for use with dialysis and like apparatus
US4828543A (en) * 1986-04-03 1989-05-09 Weiss Paul I Extracorporeal circulation apparatus
WO1994025875A1 (en) * 1993-04-29 1994-11-10 Danfoss A/S Device for analyzing a fluid medium
US5372709A (en) * 1988-12-13 1994-12-13 Bio-Flo Limited Fluid flow control apparatus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1573147A (en) * 1967-05-31 1969-07-04
JPS59170742A (en) * 1983-02-17 1984-09-27 Mitsui Toatsu Chem Inc Continuous measuring device of trace material

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366051A (en) * 1976-11-19 1982-12-28 Halbert Fischel Hemodialysis system
WO1981000911A1 (en) * 1979-09-19 1981-04-02 Charles Hospital Dev Continuous flow automatic chemical analysis systems and components for use therein
US4432806A (en) * 1981-01-14 1984-02-21 Aktieselskabet De Danske Sukkerfabrikker Method of purifying sugar juice prepared by extraction of a sugar beet material
US4503333A (en) * 1981-06-05 1985-03-05 Baxter Travenol Laboratories Antimicrobial ultraviolet irradiation of connector for continuous ambulatory peritoneal dialysis
US4552552A (en) * 1982-02-16 1985-11-12 Fresenius Ag Pump system for use with dialysis and like apparatus
EP0107631A2 (en) * 1982-09-28 1984-05-02 Bifok Ab Integrated microconduits for continuous flow analysis
US4828543A (en) * 1986-04-03 1989-05-09 Weiss Paul I Extracorporeal circulation apparatus
US5372709A (en) * 1988-12-13 1994-12-13 Bio-Flo Limited Fluid flow control apparatus
WO1994025875A1 (en) * 1993-04-29 1994-11-10 Danfoss A/S Device for analyzing a fluid medium

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8597230B2 (en) 2007-07-05 2013-12-03 Baxter International Inc. Dialysis system having supply container autoconnection
US11730868B2 (en) 2007-07-05 2023-08-22 Baxter International Inc. Dialysis system having an autoconnection mechanism
US7736328B2 (en) 2007-07-05 2010-06-15 Baxter International Inc. Dialysis system having supply container autoconnection
US8157761B2 (en) 2007-07-05 2012-04-17 Baxter International Inc. Peritoneal dialysis patient connection system
US8197087B2 (en) 2007-07-05 2012-06-12 Baxter International Inc. Peritoneal dialysis patient connection system using ultraviolet light emitting diodes
US8257299B2 (en) 2007-07-05 2012-09-04 Baxter International Dialysis methods and systems having autoconnection and autoidentification
US8764702B2 (en) 2007-07-05 2014-07-01 Baxter International Inc. Dialysis system having dual patient line connection and prime
US8469545B2 (en) 2007-07-05 2013-06-25 Baxter Healthcare Inc. Peritoneal dialysis connection system and method for using ultraviolet light emitting diodes
US8083709B2 (en) 2007-07-05 2011-12-27 Baxter International Inc. Dialysis method having supply container autoconnection
US11311657B2 (en) 2007-07-05 2022-04-26 Baxter International Inc. Dialysis system for mixing treatment fluid at time of use
US8986243B2 (en) 2007-07-05 2015-03-24 Baxter International Inc. Peritoneal dialysis patient connection system
US8911109B2 (en) 2007-07-05 2014-12-16 Baxter Healthcare Inc. Peritoneal dialysis connection system and method for using ultraviolet light emitting diodes
US10335532B2 (en) 2007-07-05 2019-07-02 Baxter International Inc. Dialysis system having autoidentification mechanism
US9586003B2 (en) 2007-07-05 2017-03-07 Baxter International Inc. Medical fluid machine with supply autoconnection
US10293091B2 (en) 2007-07-05 2019-05-21 Baxter International Inc. Dialysis system having an autoconnection mechanism
US9931454B2 (en) 2008-11-21 2018-04-03 Baxter International Inc. Dialysis machine having auto-connection system with roller occluder
US9044544B2 (en) 2008-11-21 2015-06-02 Baxter International Inc. Dialysis machine having auto-connection system with roller occluder
US20110154918A1 (en) * 2009-12-30 2011-06-30 Syage Jack A Surface sampling mobile chemical detection probe
US8402842B2 (en) 2009-12-30 2013-03-26 Morpho Detection, Inc Surface sampling mobile chemical detection probe

Also Published As

Publication number Publication date
AU3379995A (en) 1996-03-27
WO1996007885A1 (en) 1996-03-14
AU689637B2 (en) 1998-04-02
EP0779974A1 (en) 1997-06-25
SE9402980D0 (en) 1994-09-07
SE504779C2 (en) 1997-04-21
SE9402980L (en) 1996-03-08

Similar Documents

Publication Publication Date Title
US5843379A (en) Sampling device for a chemical analysis apparatus
CA2175228A1 (en) Apparatus for assaying viscosity changes in fluid samples and method of conducting same
Liu et al. A membrane-based, high-efficiency, microfluidic debubbler
EP0998352B1 (en) Microfluidic analyzer module
CA2456276C (en) Sheet-form membrane sample probe, method and apparatus for fluid concentration analysis
ATE479890T1 (en) MICRO-Fabricated DEVICE, METHOD FOR MULTIPLEXED ELECTROKINETIC ADJUSTMENT OF LIQUID FLOWS AND FLOW CYTOMETRY METHOD FOR USING THE DEVICE
US6562211B1 (en) Membrane probe for taking samples of an analyte located in a fluid medium
JP3025015B2 (en) Fluid medium analyzer
ATE279972T1 (en) MICROCOMPONENT DEVICE FOR EFFICIENTLY CONTACTING A FLUID
AU7189000A (en) Microdroplet dispensing for a medical diagnostic device
WO2000043748A1 (en) Fluid flow module
JPH09509466A (en) Fluid micro diode
Campos et al. Applications of autonomous microfluidic systems in environmental monitoring
KR20060127933A (en) Detection cartridges, modules, systems and methods
WO2001026813A2 (en) Microfluidics without electrically of mechanically operated pumps
WO2002022266A3 (en) Fluid cartridge and method
JP2009517650A (en) Microfluidic device with porous membrane and unbranched channel
WO2005111629A1 (en) Microanalysis apparatus with constant pressure pump system
CA2263943A1 (en) Sampler
EP1486777B1 (en) Sensor format and construction method for capillary-filled diagnostic sensor
US11702650B2 (en) Chromatographic test device
JPH0252978B2 (en)
JP3096609U (en) Thin film transmission measurement cell, thin film transmission measurement device
US20050210996A1 (en) Flow channel structure and method
WO2010091685A1 (en) Degassing unit for micro fluid system

Legal Events

Date Code Title Description
AS Assignment

Owner name: DANFOSS A/S, DENMARK

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:KRISTENSEN, STEEN GAARDSTED;REEL/FRAME:008541/0688

Effective date: 19970207

REMI Maintenance fee reminder mailed
LAPS Lapse for failure to pay maintenance fees
STCH Information on status: patent discontinuation

Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362

FP Lapsed due to failure to pay maintenance fee

Effective date: 20021201