|Veröffentlichungsdatum||20. Apr. 2010|
|Eingetragen||29. Nov. 2004|
|Prioritätsdatum||5. Okt. 2001|
|Auch veröffentlicht unter||US8055326|
|Veröffentlichungsnummer||10998395, 998395, US 7701209 B1, US 7701209B1, US-B1-7701209, US7701209 B1, US7701209B1|
|Erfinder||Charles A. Green|
|Ursprünglich Bevollmächtigter||Fonar Corporation|
|Zitat exportieren||BiBTeX, EndNote, RefMan|
|Patentzitate (164), Nichtpatentzitate (7), Referenziert von (31), Klassifizierungen (11), Juristische Ereignisse (6)|
|Externe Links: USPTO, USPTO-Zuordnung, Espacenet|
The present application is a continuation-in-part of U.S. application Ser. No. 10/266,070, filed Oct. 7, 2002, entitled “Coils For Horizontal Field Magnetic Resonance Imaging” and claims the benefit of the filing date of U.S. Provisional Application Nos. 60/327,329, filed Oct. 5, 2001 and 60/342,832, filed Dec. 20, 2001, the disclosures of which are hereby incorporated herein by reference.
The present invention relates to magnetic resonance imaging apparatus and procedures. In magnetic resonance imaging, an object to be imaged as, for example, a body of a human subject, is exposed to a strong, substantially constant static magnetic field. Radio frequency excitation energy is applied to the body, and this energy causes the spin vectors of certain atomic nuclei within the body to rotate or “precess” around axes parallel to the direction of the static magnetic field. The precessing atomic nuclei emit weak radio frequency signals during the relaxation process, referred to herein as magnetic resonance signals. Different tissues produce different signal characteristics. Furthermore, relaxation times are a major factor in determining signal strength. In addition, tissues having a high density of certain nuclei will produce stronger signals than tissues with F a low density of such nuclei. Relatively small gradients in the magnetic field are superimposed on the static magnetic field at various times during the process so that magnetic resonance signals from different portions of the patient's body differ in phase and/or frequency. If the process is repeated numerous times using different combinations of gradients, the signals from the various repetitions together provide enough information to form a map of signal characteristics versus location within the body. Such a map can be reconstructed by conventional techniques well known in the magnetic resonance imaging art, and can be displayed as a pictorial image of the tissues as known in the art.
The magnetic resonance imaging technique offers numerous advantages over other imaging techniques. MRI does not expose either the patient or medical personnel to X-rays and offers important safety advantages. Also, magnetic resonance imaging can obtain images of soft tissues and other features within the body which are not readily visualized using other imaging techniques. Accordingly, magnetic resonance imaging has been widely adopted in the medical and allied arts.
Several factors impose significant physical constraints in the positioning of patients and ancillary equipment in MRI imaging. Many MRI magnets use one or more solenoidal superconducting coils to provide the static magnetic field arranged so that the patient is disposed within a small tube running through the center of the magnet. The magnet and tube typically extend along a horizontal axis, so that the long axis or head-to-toe axis of the patient's body must be in a horizontal position during the procedure. Moreover, equipment of this type provides a claustrophobic environment for the patient. Iron core magnets have been built to provide a more open environment for the patient. These magnets typically have a ferromagnetic frame with a pair of ferromagnetic poles disposed one over the other along a vertical pole axis with a gap between them for receiving the patient. The frame includes ferromagnetic flux return members such as plates or columns extending vertically outside of the patient-receiving gap. A magnetic field is provided by permanent magnets or electromagnetic coils associated with the frame. A magnet of this type can be designed to provide a more open environment for the patient. However, it is still generally required for the patient to lie with his or her long axis horizontal.
Recently, ferromagnetic frame magnets having horizontal pole axes have been developed. As disclosed, for example, in commonly assigned U.S. patent application Ser. No. 08/978,084, filed on Nov. 25, 1997, and U.S. Pat. Nos. 6,414,490 and 6,677,753, the disclosures of which are incorporated by reference herein, a magnet having poles spaced apart from one another along a horizontal axis provides a horizontally oriented magnetic field within a patient-receiving gap between the poles. Such a magnet can be used with a patient positioning device including elevation and tilt mechanisms to provide extraordinary versatility in patient positioning. For example, where the patient positioning device includes a bed or similar device for supporting the patient in a recumbent position, the bed can be tilted and/or elevated so as to image the patient in essentially any position between a fully standing position and a fully recumbent position, and can be elevated so that essentially any portion of the patient's anatomy is disposed within the gap in an optimum position for imaging. As further disclosed in the aforesaid applications, the patient positioning device may include additional elements such as a platform projecting from the bed to support the patient when the bed is tilted towards a standing orientation. Still other patient supporting devices can be used in place of a bed in a system of this type. For example, a seat may be used to support a patient in a sitting position. Thus, magnets of this type provide extraordinary versatility in imaging.
Another physical constraint on MRI imaging has been posed by the requirements for RF antennas to transmit the RF excitation energy and to receive the magnetic resonance signals from the patient. The antenna that receives the signals is positioned near that portion of the patient's body that is to be imaged so as to maximize the signal-to-noise ratio and improve reception of the weak magnetic resonance signals. The antenna that applies RF excitation energy can be positioned in a similar location to maximize efficiency of the applied RF energy. In some cases, the same antenna is used to apply RF excitation energy and to receive the magnetic resonance signals at different times during the process. However, it is often desirable to provide two separate antennas for this purpose.
The antennas are typically formed as one or more loops of electrically conductive material. Such a loop antenna must be positioned so that the conductor constituting the loop extends along an imaginary plane or surface having a normal vector transverse to the direction of the static magnetic field. Stated another way, the antenna must be arranged to transmit or receive electromagnetic fields in a direction perpendicular to the direction of the static magnetic field if it is to interact with the precessing atomic nuclei. This requirement has further limited available antenna configurations and techniques. For example, in a vertical-field magnet such as a ferromagnetic frame magnet having a vertical pole axis, it is impossible to use a loop antenna with the loop disposed generally in a horizontal plane below the body of a recumbent patient. Such an antenna has a normal vector which is vertical and hence parallel to the direction of the static magnetic field. A loop antenna which encircles the patient with its normal vector extending horizontally can be employed. Also, planar or saddle-shaped loops extending in generally vertical planes or surfaces, and having normal vectors in the horizontal direction transverse to the long axis of the patient can be positioned on opposite sides of the patient. However, these antenna configurations do not provide optimum signal-to-noise ratios in some procedures as, for example, in imaging the spine, head or pelvic region.
In accordance with an embodiment of the present invention an apparatus for magnetic resonance imaging comprises a magnet having a patient-receiving space and a horizontal pole axis. The magnet desirably includes a source of magnetic flux that provides a static magnetic field with a field vector in a substantially horizontal direction. A patient-positioning and antenna assembly is used in combination with the magnet to position and image the region of the patient's anatomy which is of interest within the patient-receiving space. The patient-positioning and antenna assembly desirably includes a patient support having a support surface adapted to support a surface of a human body. The antenna assembly preferably includes a first antenna including one or more coils, at least some of the coils extending along coil surfaces substantially parallel to the support surface and adjacent thereto, whereby a surface of a body supported by the support surface will closely overlie the coils. The patient-positioning and antenna assembly further includes a frame for holding the patient support so that a vector normal to the support surface and the coil surface extends transverse to the pole axis and transverse to said field vector. In accordance with this embodiment of the present invention, the coils are positioned in close proximity to the region of the patient's anatomy to be imaged so that the image obtained provides more detailed information for analysis.
In accordance with another aspect of the present invention an apparatus for magnetic resonance imaging preferably comprises a magnet defining a patient-receiving space and having a static magnetic field with a field vector in a substantially horizontal direction. The apparatus desirably includes a quadrature coil antenna arrangement for receiving a signal from an object or patient disposed within the patient receiving space. The quadrature coil antenna includes a first antenna having a first coil vector and a second antenna having a second coil vector, the first and second coil vector being transverse to the static magnetic field vector. Further in accordance with this aspect of the present invention, the static magnetic field vector is oriented substantially transverse to the long axis of the patient disposed in the receiving space. This embodiment advantageously provides for better signal-to-noise performance during scanning through the use of the quadrature coil arrangement.
In yet another aspect in accordance with the present invention, an antenna arrangement for horizontal field magnetic resonance imaging preferably comprises a first antenna having a first coil vector and a second antenna having a second coil vector. The first and second antennas being desirably arranged so that the first coil vector and second coil vector are substantially transverse to each other. In addition, the first and second antennas are further desirably arranged so that the first coil vector and the second coil vector are substantially transverse to the horizontal magnetic field. In accordance with this aspect of the present invention, the static magnetic field vector is oriented substantially transverse to the long axis of the patient disposed in the receiving space. Images taken in accordance with this aspect of the present invention benefit from the improvement in signal-to-noise ratio which results in images having more detail for the operator, medical professional or user.
In another embodiment in accordance with the present invention, a magnetic resonance imaging apparatus preferably comprises a stationary magnet having a pair of elements spaced apart from one another along a horizontal axis and a patient-receiving space between the elements in combination with a quadrature coil antenna arrangement. The magnet is operable to direct magnetic flux between the elements through the patient receiving space. The antenna assembly preferably includes a first antenna having a first coil vector and a second antenna having a second coil vector. The first coil vector and second coil vector are oriented substantially transverse to the horizontal magnetic field and the horizontal magnetic field is oriented substantially transverse to the long axis of the patient disposed within the patient receiving space.
In accordance with a method aspect of the invention method for magnetic resonance imaging is provided. The method preferably comprises the steps of providing a static magnetic field in a space, the static magnetic field having a substantially horizontal magnetic field vector and positioning a patient on a patient support surface so that the patient's body preferably overlies the support and overlies one or more coils of a first antenna, the one or more coils having coil surfaces substantially parallel to the support surface and adjacent thereto. The patient support surface is then desirably positioned in the static field so that the vectors normal to the coil surfaces are substantially transverse to the field vector and magnetic resonance signals are elicited by transmitting RF energy to the body and receiving said magnetic resonance signals, at least one of the transmitting and receiving steps being performed at least in part by use of the first antenna.
In another aspect, the present invention is an apparatus for magnetic resonance imaging. The apparatus preferably comprises a magnet defining a patient-receiving space and having a static magnetic field with a field vector in a substantially horizontal direction and a patient support having a support surface for a human body. The patient support is preferably positioned within said patient-receiving space and is preferably pivotable about a horizontal pivot axis. The apparatus further desirably includes a quadrature coil antenna arrangement for receiving a signal from a patient disposed within the receiving space. The quadrature coil antenna preferably includes a first antenna having a first coil vector and a second antenna having a second coil vector, the first coil vector and said second coil vector being substantially transverse to said static magnetic field vector. The static magnetic field vector is preferably oriented substantially transverse to the long axis of a patient disposed within the patient-receiving space.
In accordance with this aspect of the present invention, the first antenna and the second antenna each comprise a coil antenna configured in a butterfly geometry.
Further in accordance with this aspect of the present invention, the first antenna and the second antenna are desirably housed in a planar structure. Further still, the planar structure comprises a quadrature surface coil that is circularly polarized in a plane perpendicular to said magnetic field axis. In addition, the first and second coil vectors are preferably transverse to each other. It is further desirably if the planar structure can be adjusted along a lengthwise direction of the patient support surface perpendicular to the magnetic field axis.
In another aspect the present invention is a magnetic resonance imaging apparatus comprising a stationary magnet having a pair of elements spaced apart from one another along a horizontal axis and a patient-receiving space between the elements. The horizontal axis is preferably substantially transverse to the long axis of a patient disposed within the patient-receiving space on a bed pivotable about an horizontal axis and the magnet is preferably operable to direct flux between said elements through said patient-receiving space.
In accordance with this aspect of the present invention, the apparatus further desirably comprises a quadrature coil antenna arrangement for receiving a signal from a body disposed within the patient-receiving space, the quadrature coil antenna including a first antenna having a first coil vector and a second antenna having a second coil vector, the first coil vector and the second coil vector being oriented substantially transverse to each other. In addition, the quadrature coil antenna arrangement is preferably housed in a planar structure having a planar surface in a plane perpendicular to the magnetic field axis.
In another aspect the present invention comprises a system for magnetic resonance imaging comprising a magnet defining a patient-receiving space and having a static magnetic field with a field vector in a substantially horizontal direction; a patient support having a surface capable of supporting a human body, the patient support being positioned within the patient-receiving space and being pivotable about a horizontal pivot axis parallel to the static magnetic field vector; and a quadrature coil antenna arrangement for receiving magnetic resonance signals from a patient disposed within the receiving space adjacent the patient support surface, the quadrature coil antenna including a first antenna having a first coil vector and a second antenna having a second coil vector, the first coil vector and the second coil vector being transverse to the static magnetic field vector.
In accordance with this aspect of the present invention, the first antenna desirably comprises a loop coil antenna and the second antenna comprises a butterfly coil antenna. In addition, the planar structure preferably comprises a quadrature surface coil that is circularly polarized in a plane perpendicular to said magnetic field axis.
Further in accordance with this aspect of the present invention, the planar structure is preferably adjustable along a lengthwise direction of the bed's surface perpendicular to the magnetic field axis.
Further in accordance with this aspect of the present invention, the first antenna preferably comprises a coil antenna configured as loop coil and the second antenna preferably comprises an antenna configured as a butterfly coil.
In another aspect, the present invention is an apparatus for magnetic resonance imaging. The apparatus preferably comprises a magnet defining a patient-receiving space and having a static magnetic field with a field vector in a substantially horizontal direction; a patient support having a support surface for a human body, said patient support being positioned within said patient-receiving space and being pivotable about a horizontal pivot axis; and a quadrature coil antenna arrangement for receiving a signal from a patient disposed within said receiving space, said quadrature coil antenna including a first antenna having a first coil vector and a second antenna having a second coil vector, said first coil vector and said second coil vector being transverse to said static magnetic field vector, and wherein said static magnetic field vector is oriented substantially transverse to the long axis of a patient disposed within said patient-receiving space. In accordance with this aspect of the present invention, the first antenna comprises a loop coil antenna and the second antenna comprises a coil antenna configured in a butterfly geometry.
In accordance with this aspect of the present invention, the loop coil antenna magnetic sensitivity is aligned anterior to posterior with respect to an anatomy of a patient supported by the patient support. It may also be desirable if the butterfly coil antenna geometry is aligned inferior to posterior with respect to an anatomy of a patient supported by the patient support.
The apparatus further includes a patient support assembly including a bed 24 defining an elongated patient supporting surface 26 having a lengthwise axis 25 and a platform 28 projecting from the supporting surface at a foot end of the bed. In addition, a seat may be mounted to supporting surface 26 to allow a patient to be positioned in a sitting position. The patient supporting assembly further includes a frame 30. Bed 24 is pivotably mounted to the frame 30 for movement about a generally horizontal pivot axis 32. Pivot axis 32 is substantially parallel to pole axis 14. Bed 24 can pivot between an upright position in which the lengthwise direction over the bed extends generally vertically as seen in
The patient support assembly further includes a first antenna schematically depicted as a planar box 34 in
The coils 36 are arrayed along the lengthwise axis 25 of bed 24 so that the coils overlap one another as shown in
The apparatus also includes, or is used in conjunction with, conventional field gradient coils (not shown) for applying magnetic field gradients within the patient-receiving space or gap 20 and an RF receiver and transmitter (not shown) for applying RF signals through one or more loops 36 of antenna 34 and for receiving magnetic resonance signals using one or more loops 36. Additionally, the apparatus includes conventional control and reconstruction equipment for actuating the various elements discussed above including the gradient coils and RF transmitter and receiver to elicit magnetic resonance signals and to convert the resulting magnetic resonance signals into a set of data defining an image of the patient. These elements may use the conventional techniques and principles of the magnetic resonance art and accordingly are not discussed in detail herein.
In a method according to a further aspect of the invention, a patient P is disposed on patient support 24 so that the patient's body overlies the support and the first antenna 34. In the position illustrated, the posterior surface of the patient's torso is closely juxtaposed to the patient support and with the first antenna so that the patient's spine is adjacent to the first antenna. The anterior-posterior axis of the patient's body is parallel to the coil vector Vc of the first antenna coils. The coil vector Vc lies in a plane perpendicular to the pole axis 14. Thus, regardless of whether it is in an upright position as seen in
Stated another way, the patient support surface 26 of support 24 lies substantially in a plane parallel to the pole axis 14 and hence parallel to the field vector of the static field magnet. This orientation allows the use of coils having coil surfaces generally parallel to the support surface. This arrangement of the support surface is different from the relative orientation of support surface and pole axis in a conventional “open” static field magnet having a vertical pole axis and a bed defining a substantially horizontal support surface, with the plane of the support surface perpendicular to the pole axis.
The same arrangement can be employed for imaging the patient in a prone position or standing position with the anterior surface of the torso facing the patient support surface 26. Also, this arrangement can be used with the patient in a sideways position, with his lateral axis (shoulder-to-shoulder axis), parallel to the coil vectors Vc. A similar arrangement can be used for imaging portions of the body other than the torso as, for example, the head or legs.
Turning now to
In this arrangement, the coil vectors Vc152 of the second antenna are substantially perpendicular to the coil vectors Vc34′ of the first antenna and the coil vectors of both antennas are substantially perpendicular to the pole axis 14 and to the static field vector B0, so that signals may be transmitted and/or received by either or both the first and second antennas. For example, the RF signals used to excite the nuclei may be transmitted by the second antenna and received by the first antenna or vice versa. Here again, the patient support may be arranged with the long axis of the patient's torso or other body structure horizontal or vertical.
Further in accordance with another aspect of the present invention, the first antenna 34′ of
In a further embodiment, schematically illustrated in
In a further variant, the patient support may have a K form other than an elongated bed. For example, as seen in
Further in accordance with this aspect of the present invention, the quadrature coil arrangement of
The seat and/or the back of a chair as described above with reference to
Until now the arrangement shown in
The arrangement shown in
Turning now to
Solenoidal coil portions 314, 316 and 318 and latches 322 and 328 form an integral detachable unit. As depicted, latches 322 and 324 and latches 328 and 330 form male-female pairs that divide the antenna 300 into a front section comprising latches 322 and 328 and solenoidal coil portions 314, 316 and 318 and a bottom section comprising first antenna 302, latch members 324 and 330, locking knobs 340 and 342, and solenoidal coil portions 344, 346 and 348. As such, the quadrature antenna 300 opens in the front by removal of the front section from the back section. Detachable front and bottom sections allow for interchangeable varying size front sections that can optimize the coil size to the patient. In addition, the exposed portion of the solenoidal coil, including the removable front section, comprises a grid-like or skeletonized structure, which results in weight reduction and minimizes claustrophobic patient responses. The front section of quadrature antenna 300 may be optionally left off to allow the first or planar antenna 302 to function as a stand-alone unit.
The quadrature antenna 302 incorporates positioning features that allow the user to attach the coil assembly to the bed 24 of
In a method in accordance with a further aspect of the invention, the quadrature antenna 300 is attached to the patient support 24. A patient P is then disposed on the patient support such that the posterior surface of the patient's torso is closely juxtaposed to the patient support and with first antenna 302. In this way the patient's spine is adjacent to the first antenna 302. The front section of the antenna 300 is then latched into place. As such, the coil vector VC302 of the first antenna 302 is perpendicular to the static magnetic field vector B0 and to the support surface 26. The coil vector VC312 of the second antenna 312 project in a direction parallel to lengthwise axis 25 while being perpendicular to static magnetic field vector B0. Both antennas are thereby available to receive the magnetic resonance signals emitted from the atomic nuclei of the patient P.
In a further variant, the one or more coils 303 shown in
Turning now to
The solenoidal antenna 404 is mounted onto a base 440. The U-shaped coils of the saddle coil antenna 424 are integrated with the solenoidal antenna 404 to form a skeletal structure into which a patient's head may be inserted. The antenna 400 may be attached to the patient bed 24 via the base 440 and vertically adjusted along the bed to adjust the patient's anatomy. The antenna may also be easily locked into place anywhere along the vertical axis 25 of the bed 24. The attachment, vertical adjustment and locking features are described in the '843 application. The saddle coil 424 enhances the sensitivity in the direction of the static magnetic field vector (B0 in
In a further variant, the coil 400 may be implemented so as to include separable portions or with a flip-up like visor. In such an embodiment, electrical continuity may be maintained by including male-female sockets at the separation points.
In accordance with an additional method aspect of the present invention, quadrature coil antenna 400 is attached to the patient support 24. A patient P is then disposed on the patient support such that the patient's head is placed in the quadrature coil antenna 400. Stabilizing clamps 450 may then be used to stabilize the patient's head. In this position, the coil vector VC404 of solenoidal coil antenna 404 projects in a direction parallel to lengthwise axis 25 and perpendicular to static field vector B0. Saddle coil vector VC424 projects in a direction transverse to the support surface 26 and is also perpendicular to static field vector B0. The patient's head may then be scanned with the patient support rotated or positioned in the many orientations discussed hereinabove. In particular, the adjustable clamps 450 provide stabilization with the patient rotated or titled in many positions previously discussed hereinabove in relation to
Turning now to
In a first embodiment, knee-coil 500 may be implemented to open at latch members 518 and 520 (see
In accordance with a further variant, knee coil 500 may be implemented as a single integrated unit, which is then pulled over a patient's foot up to the patient's knee. In addition, the knee coil 500 may also be implemented such that it swings open at either latch 518 or 520.
In addition to the magnet structure shown in
In accordance with the embodiment shown in
Turning now to
As shown, each coil 1304, 1306 includes a pair of tap off points 1314 1,2, 1316 1,2 at which circuitry necessary to the operation of the coils may be located. Such circuitry serve to decouple the individual antennas, define a resonant antenna circuit and output the magnetic resonance signals received (e.g., see output port 1320).
The quadrature surface coil antenna 1300 may be used in the apparatus 1 shown in
In addition, the quadrature coil antenna 1300 is advantageously circularly polarized in a plane perpendicular to the direction of the static magnetic field B0. The antenna 1300 desirably produces it strongest magnetic sensitivity at the intersection of the butterfly elements. Therefore, the symmetry of the arrangement produces an even circular illumination of the anatomy with signal-to-noise that is approximately 40% greater than a single butterfly coil. As discussed, the antenna 1300 is preferably flat and is positionable parallel to the surface of the poles of the magnet. However, the antenna may be similarly used even in a magnet without distinct poles as long as the coil vectors are oriented perpendicular to the direction of the static magnetic field. As such, the quadrature surface 1300 is also adaptable to imaging in a vertical field system with the coil surface parallel to the patient support surface.
Turning now to
In accordance with this aspect of the present invention, the planar coil assembly 1400 may be used with the system of
In accordance with this aspect of the present invention, the loop coil typically augments the signal of the butterfly coil where the butterfly coil tends to be weakest. In addition, the butterfly coil typically augments the signal received by the loop coil where the loop coil tends to be weakest. The antenna coil 1400 is advantageously circularly polarized in a plane perpendicular to the horizontal field B0 of the magnet. Therefore, the antenna coil 1400 may used in any magnet geometry where the antenna coil is circularly polarized in a plane perpendicular to the horizontal field of the magnet.
Although the invention herein has been described with reference to particular embodiments, it is to be understood that these embodiments are merely illustrative of the principles and applications of the present invention. It is therefore to be understood that numerous modifications may be made to the illustrative embodiments and that other arrangements may be devised without departing from the spirit and scope of the present invention as defined by the appended claims. In particular, quadrature coils may be designed for many more parts of the human anatomy, e.g., the ankle, wrist, shoulder, neck, foot, breast, etc., that would provide improved signal-to-noise ratio performance.
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|Unternehmensklassifikation||G01R33/3806, A61B5/0555, G01R33/341, G01R33/3678, G01R33/307|
|Europäische Klassifikation||G01R33/36Q, G01R33/341, G01R33/30S|
|17. März 2005||AS||Assignment|
Owner name: FONAR CORPORATION,NEW YORK
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