WO1987005225A2 - Pressure-measurement flow control system - Google Patents

Pressure-measurement flow control system Download PDF

Info

Publication number
WO1987005225A2
WO1987005225A2 PCT/US1987/000515 US8700515W WO8705225A2 WO 1987005225 A2 WO1987005225 A2 WO 1987005225A2 US 8700515 W US8700515 W US 8700515W WO 8705225 A2 WO8705225 A2 WO 8705225A2
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
pressure
measurement
region
increments
Prior art date
Application number
PCT/US1987/000515
Other languages
French (fr)
Other versions
WO1987005225A3 (en
WO1987005225A1 (en
Inventor
Dean L Kamen
Original Assignee
Dean L Kamen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dean L Kamen filed Critical Dean L Kamen
Priority to DE8787902007T priority Critical patent/DE3775318D1/en
Publication of WO1987005225A2 publication Critical patent/WO1987005225A2/en
Publication of WO1987005225A1 publication Critical patent/WO1987005225A1/en
Publication of WO1987005225A3 publication Critical patent/WO1987005225A3/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K31/00—Actuating devices; Operating means; Releasing devices
    • F16K31/004—Actuating devices; Operating means; Releasing devices actuated by piezoelectric means
    • F16K31/005—Piezo-electric benders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16809—Flow controllers by repeated filling and emptying of an intermediate volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16813—Flow controllers by controlling the degree of opening of the flow line
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
    • A61M5/16859—Evaluation of pressure response, e.g. to an applied pulse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A61M5/365—Air detectors
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/08—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the diaphragm or bellows type
    • G01F11/086—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the diaphragm or bellows type using an auxiliary pressure to cooperate with the diaphragm or bellows
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01P—MEASURING LINEAR OR ANGULAR SPEED, ACCELERATION, DECELERATION, OR SHOCK; INDICATING PRESENCE, ABSENCE, OR DIRECTION, OF MOVEMENT
    • G01P13/00—Indicating or recording presence, absence, or direction, of movement
    • G01P13/0006—Indicating or recording presence, absence, or direction, of movement of fluids or of granulous or powder-like substances
    • G01P13/0066—Indicating or recording presence, absence, or direction, of movement of fluids or of granulous or powder-like substances by using differences of pressure in the fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M2005/1401—Functional features
    • A61M2005/1403—Flushing or purging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/15—Detection of leaks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/26—Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/12—Pressure infusion
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/13—Infusion monitoring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/7722—Line condition change responsive valves
    • Y10T137/7781—With separate connected fluid reactor surface
    • Y10T137/7782—With manual or external control for line valve
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/7722—Line condition change responsive valves
    • Y10T137/7781—With separate connected fluid reactor surface
    • Y10T137/7793—With opening bias [e.g., pressure regulator]
    • Y10T137/7796—Senses inlet pressure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87917—Flow path with serial valves and/or closures
    • Y10T137/87981—Common actuator
    • Y10T137/87997—Alternately seating
    • Y10T137/88005—Biased valve

Abstract

A system for controlling flow of a first fluid through a line (14). Dispensing means (131, 132, 141) isolates a region (141) of the first fluid in the line (14) from effects of pressure in the line (14) outside of the region (141). The dispensing means (131, 132, 141) repetitively dispenses increments of first fluid into and out of the region (141). Measurement fluid is housed (13) in communication with the region (141) such that the dispensing of increments of first fluid into or out of the region (141) causes a change in the measurement fluid pressure. Displacement means (161, 162) displaces a predetermined volume increment of measurement fluid into and out of the measurement fluid housing (13), such that displacement of the predetermined volume increment causes a change in the measurement fluid pressure when the region is isolated by the dispensing means (131, 132, 141). Pressure measurement means (15) changes in the measurement fluid pressure. Control means (81) in communication with the pressure measurement means (15), the displacement means (161, 162), and the dispensing means (131, 132, 141), causes the dispensing means (131, 132, 141) to dispense first fluid in increments based on data from the pressure measurement means (15), such that at least one one of the predetermined volume increments of measurement fluid displaced serves as a reference for the volume increments of first fluid outputted.
PCT/US1987/000515 1986-03-04 1987-03-04 Pressure-measurement flow control system WO1987005225A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE8787902007T DE3775318D1 (en) 1986-03-04 1987-03-04 FLOW CONTROL SYSTEM BY MEANS OF PRESSURE MEASUREMENT.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/836,023 US4778451A (en) 1986-03-04 1986-03-04 Flow control system using boyle's law
US836,023 1986-03-04

Publications (3)

Publication Number Publication Date
WO1987005225A2 true WO1987005225A2 (en) 1987-09-11
WO1987005225A1 WO1987005225A1 (en) 1987-09-11
WO1987005225A3 WO1987005225A3 (en) 1987-11-19

Family

ID=

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0406562A2 (en) * 1989-06-07 1991-01-09 Abbott Laboratories Apparatus and method to test for valve leakage in a pump assembly
WO1990013795A3 (en) * 1989-05-01 1991-01-10 Deka Products Lp Enhanced pressure measurement flow control system
GR900100032A (en) * 1989-01-20 1991-06-07 Inst Of Biocybernetics P A S Continuous surveillance method for the function of a supply system and apparatus therefor
EP0462405A1 (en) * 1990-06-21 1991-12-27 The Boc Group, Inc. Bubble detection system
EP0499417A1 (en) * 1991-02-14 1992-08-19 Baxter International Inc. Pumping arrangements
WO1995003079A1 (en) * 1993-07-20 1995-02-02 Volker Lang Infusion monitoring device
US5399166A (en) * 1992-11-23 1995-03-21 Laing; David H. Portable infusion device
FR2711531A1 (en) * 1993-10-29 1995-05-05 David Francois Perfusion device
US5520638A (en) * 1995-03-28 1996-05-28 Arthrex, Inc. Main pump tubing for arthroscopy infusion pump
EP0718005A1 (en) * 1994-12-21 1996-06-26 François David Infusion device
WO1998046294A1 (en) * 1997-04-11 1998-10-22 Societe Des Produits Nestle S.A. Pump system with error detection for clinical nutrition
US6010909A (en) * 1990-03-02 2000-01-04 Cytyc Corporation Method and apparatus for controlled instrumentation of particles with a filter device
US6318190B1 (en) 1996-11-01 2001-11-20 Cytyc Corporation Systems for collecting fluid samples having select concentrations of particles
EP1319417A1 (en) * 2001-12-17 2003-06-18 B. Braun Medizintechnologie GmbH Method and apparatus for monitoring a fluid conduit system of a medical instrument
US8182461B2 (en) 2003-11-04 2012-05-22 Smiths Medical Asd, Inc. Syringe pump rapid occlusion detection system
US8425780B2 (en) 2010-03-11 2013-04-23 Fresenius Medical Care Holdings, Inc. Dialysis system venting devices and related systems and methods
US8728020B2 (en) 2007-10-04 2014-05-20 Gambro Lundia Ab Infusion apparatus
US20170106140A1 (en) * 2014-03-17 2017-04-20 Roche Diabetes Care, Inc. Initialization of a dosing unit for drug infusion
US10220132B2 (en) 2014-12-19 2019-03-05 Fenwal, Inc. Biological fluid flow control apparatus and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2110349A1 (en) * 1970-10-10 1972-06-02 Leifermann Walter
WO1984004460A1 (en) * 1983-05-16 1984-11-22 Health Care Concepts Inc I.v. flow regulator
EP0156211A2 (en) * 1984-03-07 1985-10-02 Fresenius AG Pumping means for medical purposes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2110349A1 (en) * 1970-10-10 1972-06-02 Leifermann Walter
WO1984004460A1 (en) * 1983-05-16 1984-11-22 Health Care Concepts Inc I.v. flow regulator
EP0156211A2 (en) * 1984-03-07 1985-10-02 Fresenius AG Pumping means for medical purposes

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR900100032A (en) * 1989-01-20 1991-06-07 Inst Of Biocybernetics P A S Continuous surveillance method for the function of a supply system and apparatus therefor
WO1990013795A3 (en) * 1989-05-01 1991-01-10 Deka Products Lp Enhanced pressure measurement flow control system
EP0406562A2 (en) * 1989-06-07 1991-01-09 Abbott Laboratories Apparatus and method to test for valve leakage in a pump assembly
EP0406562A3 (en) * 1989-06-07 1991-06-12 Abbott Laboratories Apparatus and method to test for valve leakage in a pump assembly
US6010909A (en) * 1990-03-02 2000-01-04 Cytyc Corporation Method and apparatus for controlled instrumentation of particles with a filter device
EP0462405A1 (en) * 1990-06-21 1991-12-27 The Boc Group, Inc. Bubble detection system
EP0499417A1 (en) * 1991-02-14 1992-08-19 Baxter International Inc. Pumping arrangements
US5399166A (en) * 1992-11-23 1995-03-21 Laing; David H. Portable infusion device
WO1995003079A1 (en) * 1993-07-20 1995-02-02 Volker Lang Infusion monitoring device
US5688244A (en) * 1993-07-20 1997-11-18 Lang; Volker Apparatus for monitoring infusion
FR2711531A1 (en) * 1993-10-29 1995-05-05 David Francois Perfusion device
EP0718005A1 (en) * 1994-12-21 1996-06-26 François David Infusion device
US5520638A (en) * 1995-03-28 1996-05-28 Arthrex, Inc. Main pump tubing for arthroscopy infusion pump
US6634244B2 (en) 1996-11-01 2003-10-21 Cytyc Corporation Methods for collecting fluid samples having select concentrations of particles
US6318190B1 (en) 1996-11-01 2001-11-20 Cytyc Corporation Systems for collecting fluid samples having select concentrations of particles
WO1998046294A1 (en) * 1997-04-11 1998-10-22 Societe Des Produits Nestle S.A. Pump system with error detection for clinical nutrition
US5951510A (en) * 1997-04-11 1999-09-14 Nestec S.A. Pump system with error detection for clinical nutrition
EP1319417A1 (en) * 2001-12-17 2003-06-18 B. Braun Medizintechnologie GmbH Method and apparatus for monitoring a fluid conduit system of a medical instrument
US8182461B2 (en) 2003-11-04 2012-05-22 Smiths Medical Asd, Inc. Syringe pump rapid occlusion detection system
US8900213B2 (en) 2003-11-04 2014-12-02 Brian Pope Syringe pump rapid occlusion detection system
US9427521B2 (en) 2003-11-04 2016-08-30 Smiths Medical Asd, Inc. Syringe pump rapid occlusion detection system
US8728020B2 (en) 2007-10-04 2014-05-20 Gambro Lundia Ab Infusion apparatus
US8425780B2 (en) 2010-03-11 2013-04-23 Fresenius Medical Care Holdings, Inc. Dialysis system venting devices and related systems and methods
US20170106140A1 (en) * 2014-03-17 2017-04-20 Roche Diabetes Care, Inc. Initialization of a dosing unit for drug infusion
US10159784B2 (en) * 2014-03-17 2018-12-25 Roche Diabetes Care, Inc. Initialization of a dosing unit for drug infusion
US10220132B2 (en) 2014-12-19 2019-03-05 Fenwal, Inc. Biological fluid flow control apparatus and method

Also Published As

Publication number Publication date
EP0262182B1 (en) 1991-12-18
DE3770221D1 (en) 1991-06-27
DE3773091D1 (en) 1991-10-24
EP0258424A1 (en) 1988-03-09
EP0262182A1 (en) 1988-04-06
WO1987005223A1 (en) 1987-09-11
JPS63503117A (en) 1988-11-17
AU7162187A (en) 1987-09-28
CA1282737C (en) 1991-04-09
WO1987005225A3 (en) 1987-11-19
EP0259464A1 (en) 1988-03-16
WO1987005224A1 (en) 1987-09-11
JP2551803B2 (en) 1996-11-06
AU7164687A (en) 1987-09-28
DE3775318D1 (en) 1992-01-30
JPH01501446A (en) 1989-05-25
JPS63503116A (en) 1988-11-17
US5241985A (en) 1993-09-07
EP0259464B1 (en) 1991-05-22
US4808161A (en) 1989-02-28
CA1278843C (en) 1991-01-08
EP0262182A4 (en) 1990-07-04
AU7161887A (en) 1987-09-28
US4804360A (en) 1989-02-14
US4816019A (en) 1989-03-28
EP0258424B1 (en) 1991-09-18
US4778451A (en) 1988-10-18

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