WO1995031728A1 - Method of detecting cancer involving fragments of cytokeratin 18 and corresponding antibodies - Google Patents
Method of detecting cancer involving fragments of cytokeratin 18 and corresponding antibodies Download PDFInfo
- Publication number
- WO1995031728A1 WO1995031728A1 PCT/SE1995/000532 SE9500532W WO9531728A1 WO 1995031728 A1 WO1995031728 A1 WO 1995031728A1 SE 9500532 W SE9500532 W SE 9500532W WO 9531728 A1 WO9531728 A1 WO 9531728A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- glu
- leu
- amino
- acid sequence
- ala
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4741—Keratin; Cytokeratin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU25821/95A AU2582195A (en) | 1994-05-17 | 1995-05-15 | Method of detecting cancer involving fragments of cytokeratin 18 and corresponding antibodies |
EP95920334A EP0765479A1 (en) | 1994-05-17 | 1995-05-15 | Method of detecting cancer involving fragments of cytokeratin 18 and corresponding antibodies |
JP7529563A JPH10500408A (en) | 1994-05-17 | 1995-05-15 | Methods for detecting cancer with fragments of cytokeratin 18 and corresponding antibodies |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9401687A SE9401687D0 (en) | 1994-05-17 | 1994-05-17 | Method of detecting cancer |
SE9401687-0 | 1994-05-17 | ||
SE9500023A SE9500023L (en) | 1994-05-17 | 1995-01-04 | Ways to detect cancer |
SE9500023-8 | 1995-01-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995031728A1 true WO1995031728A1 (en) | 1995-11-23 |
Family
ID=26662055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE1995/000532 WO1995031728A1 (en) | 1994-05-17 | 1995-05-15 | Method of detecting cancer involving fragments of cytokeratin 18 and corresponding antibodies |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0765479A1 (en) |
JP (1) | JPH10500408A (en) |
AU (1) | AU2582195A (en) |
SE (1) | SE9500023L (en) |
WO (1) | WO1995031728A1 (en) |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
US5741650A (en) * | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
US5872209A (en) * | 1996-01-18 | 1999-02-16 | Hoechst Aktiengesellschaft | Artificial recombinant substrate (rAGG 1) and native aggrecan to determine the proteolytic activity of `aggrecanase` in cell culture systems |
WO1999014372A1 (en) * | 1997-09-15 | 1999-03-25 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the urinary tract |
US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US5952178A (en) * | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
US6020137A (en) * | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6100029A (en) * | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
US6146828A (en) * | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
US6280947B1 (en) | 1999-08-11 | 2001-08-28 | Exact Sciences Corporation | Methods for detecting nucleotide insertion or deletion using primer extension |
US6300077B1 (en) | 1996-08-14 | 2001-10-09 | Exact Sciences Corporation | Methods for the detection of nucleic acids |
EP1204419A1 (en) * | 1999-08-13 | 2002-05-15 | The Brigham And Women's Hospital, Inc. | Inhibitors of the lectin complement pathway (lcp) and their use |
WO2002055555A3 (en) * | 2000-12-21 | 2003-02-27 | Genzyme Corporation | Antigenic ck-18 compounds for therapy and diagnosis and methods for using same |
WO2003086456A2 (en) * | 2002-04-05 | 2003-10-23 | Arius Research, Inc. | Anti-ck18 monoclonal antibody and therapeutic and diagnostic uses thereof in cancer |
US6734287B1 (en) * | 1998-04-09 | 2004-05-11 | Idexx Laboratories, Inc. | Specific binding proteins for treating canine allergy |
WO2005074968A2 (en) * | 2004-02-10 | 2005-08-18 | Universiteit Maastricht | Medical use of basic peptides |
WO2007136674A1 (en) * | 2006-05-19 | 2007-11-29 | The Cleveland Clinic Foundation | Detection and monitoring of liver damage |
US7393529B2 (en) | 1998-04-09 | 2008-07-01 | Idexx Laboratories, Inc. | Methods and compositions for inhibiting binding of IgE to a high affinity receptor |
US8524453B2 (en) | 2006-02-10 | 2013-09-03 | The Brigham And Woman's Hospital, Inc. | Lectin complement pathway assays and related compositions and methods |
US9109256B2 (en) | 2004-10-27 | 2015-08-18 | Esoterix Genetic Laboratories, Llc | Method for monitoring disease progression or recurrence |
US9777314B2 (en) | 2005-04-21 | 2017-10-03 | Esoterix Genetic Laboratories, Llc | Analysis of heterogeneous nucleic acid samples |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007076439A2 (en) * | 2005-12-22 | 2007-07-05 | Abbott Laboratories | Methods and marker combinations for screening for predisposition to lung cancer |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4775620A (en) * | 1984-01-06 | 1988-10-04 | The Regents Of The University Of California | Cytokeratin tumor markers and assays for their detection |
EP0337057A1 (en) * | 1988-01-26 | 1989-10-18 | PROGEN Biotechnik GmbH | Method to identify the origin of a cell or tissue sample |
DE3923951A1 (en) * | 1989-07-19 | 1991-01-31 | Boehringer Mannheim Gmbh | METHOD FOR DETECTING LIVER CIRRUS |
-
1995
- 1995-01-04 SE SE9500023A patent/SE9500023L/en not_active Application Discontinuation
- 1995-05-15 WO PCT/SE1995/000532 patent/WO1995031728A1/en not_active Application Discontinuation
- 1995-05-15 EP EP95920334A patent/EP0765479A1/en not_active Withdrawn
- 1995-05-15 AU AU25821/95A patent/AU2582195A/en not_active Abandoned
- 1995-05-15 JP JP7529563A patent/JPH10500408A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4775620A (en) * | 1984-01-06 | 1988-10-04 | The Regents Of The University Of California | Cytokeratin tumor markers and assays for their detection |
EP0337057A1 (en) * | 1988-01-26 | 1989-10-18 | PROGEN Biotechnik GmbH | Method to identify the origin of a cell or tissue sample |
DE3923951A1 (en) * | 1989-07-19 | 1991-01-31 | Boehringer Mannheim Gmbh | METHOD FOR DETECTING LIVER CIRRUS |
Non-Patent Citations (5)
Cited By (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5872209A (en) * | 1996-01-18 | 1999-02-16 | Hoechst Aktiengesellschaft | Artificial recombinant substrate (rAGG 1) and native aggrecan to determine the proteolytic activity of `aggrecanase` in cell culture systems |
US5741650A (en) * | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
US6300077B1 (en) | 1996-08-14 | 2001-10-09 | Exact Sciences Corporation | Methods for the detection of nucleic acids |
US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
US5952178A (en) * | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
US6020137A (en) * | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6100029A (en) * | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
US6146828A (en) * | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
US6303304B1 (en) | 1996-08-14 | 2001-10-16 | Exact Laboratories, Inc. | Methods for disease diagnosis from stool samples |
US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6207380B1 (en) | 1997-09-15 | 2001-03-27 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the urinary tract |
WO1999014372A1 (en) * | 1997-09-15 | 1999-03-25 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the urinary tract |
US6734287B1 (en) * | 1998-04-09 | 2004-05-11 | Idexx Laboratories, Inc. | Specific binding proteins for treating canine allergy |
US8252907B2 (en) | 1998-04-09 | 2012-08-28 | Idexx Laboratories, Inc. | Methods and compositions for inhibiting binding of IgE to a high affinity receptor |
US7931898B2 (en) | 1998-04-09 | 2011-04-26 | Idexx Laboratories, Inc. | Methods and compositions for inhibiting binding of IgE to a high affinity receptor |
US7393529B2 (en) | 1998-04-09 | 2008-07-01 | Idexx Laboratories, Inc. | Methods and compositions for inhibiting binding of IgE to a high affinity receptor |
US6280947B1 (en) | 1999-08-11 | 2001-08-28 | Exact Sciences Corporation | Methods for detecting nucleotide insertion or deletion using primer extension |
EP1204419A1 (en) * | 1999-08-13 | 2002-05-15 | The Brigham And Women's Hospital, Inc. | Inhibitors of the lectin complement pathway (lcp) and their use |
WO2002055555A3 (en) * | 2000-12-21 | 2003-02-27 | Genzyme Corporation | Antigenic ck-18 compounds for therapy and diagnosis and methods for using same |
WO2003086456A3 (en) * | 2002-04-05 | 2003-12-04 | Arius Res Inc | Anti-ck18 monoclonal antibody and therapeutic and diagnostic uses thereof in cancer |
WO2003086456A2 (en) * | 2002-04-05 | 2003-10-23 | Arius Research, Inc. | Anti-ck18 monoclonal antibody and therapeutic and diagnostic uses thereof in cancer |
WO2005074968A2 (en) * | 2004-02-10 | 2005-08-18 | Universiteit Maastricht | Medical use of basic peptides |
WO2005074968A3 (en) * | 2004-02-10 | 2005-12-08 | Univ Maastricht | Medical use of basic peptides |
US9109256B2 (en) | 2004-10-27 | 2015-08-18 | Esoterix Genetic Laboratories, Llc | Method for monitoring disease progression or recurrence |
US9777314B2 (en) | 2005-04-21 | 2017-10-03 | Esoterix Genetic Laboratories, Llc | Analysis of heterogeneous nucleic acid samples |
US8524453B2 (en) | 2006-02-10 | 2013-09-03 | The Brigham And Woman's Hospital, Inc. | Lectin complement pathway assays and related compositions and methods |
WO2007136674A1 (en) * | 2006-05-19 | 2007-11-29 | The Cleveland Clinic Foundation | Detection and monitoring of liver damage |
US7883904B2 (en) | 2006-05-19 | 2011-02-08 | The Cleveland Clinic Foundation | Detection and monitoring of liver damage |
US8409878B2 (en) | 2006-05-19 | 2013-04-02 | The Cleveland Clinic Foundation | Detection and monitoring of liver damage |
US8460943B2 (en) | 2006-05-19 | 2013-06-11 | The Cleveland Clinic Foundation | Detection and monitoring of liver damage |
Also Published As
Publication number | Publication date |
---|---|
JPH10500408A (en) | 1998-01-13 |
AU2582195A (en) | 1995-12-05 |
EP0765479A1 (en) | 1997-04-02 |
SE9500023L (en) | 1995-11-18 |
SE9500023D0 (en) | 1995-01-04 |
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