WO1997032129A1 - Rapid infusion system - Google Patents
Rapid infusion system Download PDFInfo
- Publication number
- WO1997032129A1 WO1997032129A1 PCT/US1997/003408 US9703408W WO9732129A1 WO 1997032129 A1 WO1997032129 A1 WO 1997032129A1 US 9703408 W US9703408 W US 9703408W WO 9732129 A1 WO9732129 A1 WO 9732129A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fluid
- patient
- reservoir
- pump
- infusion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B17/00—Pumps characterised by combination with, or adaptation to, specific driving engines or motors
- F04B17/03—Pumps characterised by combination with, or adaptation to, specific driving engines or motors driven by electric motors
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B2203/00—Motor parameters
- F04B2203/02—Motor parameters of rotating electric motors
- F04B2203/0209—Rotational speed
Definitions
- This invention relates to an apparatus for the rapid infusion of circulatory supportive fluids such as blood into a patient.
- the system comprises permanent components.
- the various components which physically come into contact with the fluid being infused can easily be removed and sterilized.
- the principal advantage achieved from this arrangement resides in the fact that it is small, lightweight, and portable.
- the system can be of a size to fit in a person's hand and is ideal for use by emergency personnel.
- a common method of rapid infusion includes the use of a plurality of infusion sites simultaneously. Infusion bags or bags of stored banked blood are interconnected by intravenous tubing. Frequently, a plurality of medical personnel are required to oversee the various infusion sites and to personally ensure the flow of blood from the blood bags.
- Anesthesiologists are now regularly involved with cardiopulmonary resuscitation, trauma and organ transplantation procedures, and with maintenance of patient bodily functions during trauma and organ transplantation operations.
- patient blood loss cannot, practically speaking, be contained by the operating surgeon and must be replaced by the anesthesiologists standing in attendance. It is not uncommon for four to five anesthesiologists or technicians to stand in attendance during transplant operations lasting more than twenty-four hours attempting to infuse massive quantities of blood through five or six venous catheters.
- a rapid infusion device capable of high volume pumping composed of two units.
- a permanent unit comprising a base portion which houses an AC/DC motor, a roller pump, and other associated gauges and switches.
- a disposable unit includes a filter reservoir, heat exchange component, and associated tubing leading to the roller pump.
- the roller pump increases the volume of fluid being pumped by increasing the rpm of the pumping unit and includes a pressure control valve.
- a further object of the present invention to provide an adjustable system which is capable of high volume infusion of blood and/or volume expanding fluids into a patient.
- FIGURE 1 is a front elevational view of the rapid infusion system.
- FIGURE 2 is a sectional view of one embodiment of the present invention with a covering or container wall removed.
- FIGURE 3 is a sectional view of another embodiment of the present invention with a covering or container wall removed.
- FIGURE 4 is a sectional view of a pump mechanism used in one embodiment of the present invention.
- FIGURE 5 is a sectional view of a pump mechanism used in another embodiment of the present invention.
- FIGURE 6 is a side view of a pump mechanism which connects to the rapid infusion unit.
- FIGURE 7 is a frontal view showing an I V. pole, fluid bag and the rapid infusion system
- FIGURE 8 is a sectional view of the present invention showing the optional C. V.P. monitoring apparatus. DESCRIPTION OF THE PREFERRED EMBODIMENTS
- inventive device can be used with central lines, venous cut-down catheters, or peripheral IV s
- the present inventive device is cost effective and environmentally friendly since the actual pump mechanism can be removed and sterilized, therefore nothing need be discarded or repurchased.
- the device can be used for blood transfusions imparting motion by a pressure
- the present invention is small and portable. It can be sized
- the infuser of the present invention can be less than about 5 inches by about 2.75 inches by about 2 inches, however the size is dependent upon the
- C.V.P. central venous pressure
- C.V.P. is an indication of volume overload and can result in heart failure and pulmonary edema (or fluid) in the lungs.
- pulmonary edema or fluid
- care units and operating rooms are usually the only hospital areas capable of measuring C.V.P.
- fluid administration is gauged empirically using only the patient's blood pressure and pulse to assess the adequacy of volume replacement.
- Hyperinfusion devices are best used while simultaneously monitoring C.V.P.
- the volume and rate of flow into the patient can then be quickly and accurately adjusted to sustain an adequate C.V.P., but the complications of heart failure and pulmonary edema from fluid overload are not eliminated due to human adjustment error.
- the hyperinfuser of the present invention can optionally infuse fluids and measure C.V.P. simultaneously through a single central venous catheter.
- the small device not only hyperinfuses fluid and monitors C.V.P., but can adjust the flow rate automatically to achieve any C.V.P. the physician desires.
- the present invention not only insures the ideal infusion rate for any particular patient, but is an inexpensive alternative to large, expensive
- the present invention can include a dial to set the desired C.V.P., a screen that displays the actual C.V.P., and a mechanism that stops the pump at pre-set time intervals in order to accurately measure the C.V.P. The operator need only select how many times per minute the pump should stop, read the C.V.P., and adjust the flow rate accordingly.
- a manual mode is provided to infuse at a simple fixed rate with a switch that will halt the pump and give the operator an instantaneous C.V.P. reading.
- a control means may be optionally used which maintains the C.V.P. within a preset range.
- the adjustable pump means responds to signals from the control means and increases or decreases the fluid pressure and/or flow rate in response thereto.
- the inventive device has an alarm indicating when the IV fluid bag approaches empty.
- the rapid infusion system is composed of two major portions.
- One portion includes permanent equipment, i.e., equipment which need not be sterilized and can be used over and over again, such as the pump motor and its related controls and optional equipment such as a C.V.P. monitor and related controls, optionally a heating element and related controls and attachment means.
- the other portion includes the removable components of the system such as the pump and pump gears or rollers, blood or fluid reservoir, valves and tubing.
- the disclosed rapid infusion system is an adjustable mechanical pumping system for rapidly delivering blood and/or volume expanding fluids to a patient suffering from acute
- hypovolemia The principle of operation of the disclosed invention is one of mechanically overcoming resistance.
- Bath is used herein to describe or refer to blood and/or volume expanding fluids delivered by the system since not only blood, but any other desired fluid may be delivered by the system.
- Reservoir as used herein includes one or more standard IV bags
- the subject invention pertains to a novel system for rapid, venous infusion of a physiologic fluid, such as blood, which can include in combination a reservoir for the physiologic fluid having an inlet port for receiving the physiologic fluid and an outlet port for
- dispensing the physiologic fluid an infusion pump to propel the physiologic fluid through the system, optional means for controlling the temperature of the physiologic fluid, optional means for filtering occlusive materials from the physiologic fluid, optional means for sensing the
- the adjustable rapid infusion system comprises a reservoir having a capacity that can exceed several liters for holding a supply of physiologic fluid, the inventive infusion pump selected from the group consisting of a gear pump, a turbine pump, a
- roller head occlusive pump a nonocclusive centrifugal pump and the like; optional portions such as a pressure controlling means, a temperature controlling means; a filter to remove any
- the pump advantageously is infinitely adjustable and can provide fluid flow rates from less than about lOcc/minute to more than about 2000 cc/minute.
- the system may further include a temperature sensor at the output of the temperature controlling means for measuring and adjusting the physiologic temperature to maintain the temperature within acceptable limits.
- the system may also have readout means,
- the inventive system has a variable speed pump motor so that the amount of volume being pumped in can be increased merely by increasing the ⁇ m of the motor.
- the reservoir may contain plural stages of filters and be provided with a plurality of inlets whereby volume from multiple sources can be fed into the reservoir to satisfy any high demand requirements of a
- the system comprises a permanent portion and a removable and sterilizable portion.
- the removable portion includes pump gears and other components with
- the removable aspect of the invention provides an extra measure of protection against contamination to a subsequent patient.
- the rapid infusion device 10 comprises an on/off switch 11, a C.V.P. feedback mode on/off switch 12, a variable flow rate control 13 for use when
- pump mechanism 15 may be recessed within device 10 so that it does not extend outside device
- Device 10 also includes a C.V.P. input jack 17, a fluid flow meter 18, an A C /D C. selector
- Figure 2 is a sectional view of one embodiment of the present invention wherein device 40 has a battery pack 41 connected to a central venous pressure feedback regulator 42.
- a drive
- gear box 43 for driving a pump mechanism (not shown) connected to a shaft 44 is driven by
- Means to vary the resistance 46 is connected to battery pack 41 and motor 45 and can vary the speed of motor 44 and thus the rotational speed input to gear box 43 and the pump
- Figure 3 is a sectional view of another embodiment of the present invention wherein device 60 has a battery pack 61, a C.V.P. regulator 62, a motor 63 with shaft 64, and a motor 65 with shaft 67.
- a means to vary the resistance 66 is connected to battery pack 61, C.V.P.
- regulator 62 can vary the speed of motors 63, 65, thereby varying
- Figure 4 is a sectional view of one type of pump usable in an embodiment of the present
- Pump 80 is attached to shaft 16 of device 10 which drives pump means 82 and 83,
- Figure 5 is a sectional view of one type of pump usable in another embodiment of the
- mechanism 100 is attached to shaft 16 of device 10 which drives pump means 103 and 102, thereby imparting motion to a fluid from a reservoir received through
- opening 101 and exiting through opening 104.
- the fluid goes between pump means 102 and 103.
- Figure 6 is a side view of a pump mechanism usable with the present invention whereby shaft 122 is connected to shaft 16 of unit 10, thereby driving gear 123 which imparts motion to fluid received from a reservoir through opening 121 and exiting through opening 124.
- Raised shoulders 125 provides secure attachment to tubing or the like.
- Figure 7 is a typical I V. arrangement 140 for hanging an I V. bag 141 containing fluid which flows through tubing 143 to the rapid infusion device of the present invention 142.
- Device 142 is attached to pole 147 by attachment means 146 and imparts motion to the fluid from bag 141 and directs it through tubing 144.
- Device 142 may be powered by an external power source through cord 145.
- FIG 8 is a sectional view showing an optional C.V.P. monitoring system for the present invention.
- Pumping mechanism 160 contains a pressure probe 161 connected by a conduit 162 to the outlet 165 of the pumping mechanism. Fluid enters the pumping mechanism from a reservoir through inlet 164 whereby motion is imparted to the fluid by the pumping mechanism gears 163. The fluid pressure as it exits the pump is directed through outlet 165 and tubing 162 which communicates with pressure probe 161.
- the inventive rapid infusion system can provide continuous total replacement of adult human blood volume through any sort of hemorrhage, for an indefinite period of time and can rapidly regulate fluid temperature with minimal increase in resistance to flow, easily and rapidly administer massive quantities of blood to a single patient during a single operation, administer physiologic fluid maintained at a predetermined temperature at flow rates in excess of 2000 cc per minute, and permit simultaneous display and control of fluid temperature, flow rate, line pressure, and total volume of physiologic fluid administered.
- the system also is portable and able to be quickly and easily used in an emergency situation or by emergency personnel in the field.
- the blood delivered by the system can include clotting factors and can infuse an infinite amount of blood over an indefinite period of time based on the pump mechanism employed, the tubing sizes, etc., employed.
- the present invention can consist of multiple pumps infusing blood or the like to a patient through multiple catheters, thereby providing such fluids in volumes to the patient which are far in excess of that possible by present infusers.
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97908872A EP0827570A4 (en) | 1996-02-28 | 1997-02-27 | Rapid infusion system |
MX9708299A MX9708299A (en) | 1996-02-28 | 1997-02-27 | Dry powder inhaler delivery system. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/608,291 | 1996-02-28 | ||
US08/608,291 US5840068A (en) | 1996-02-28 | 1996-02-28 | Rapid infusion system |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997032129A1 true WO1997032129A1 (en) | 1997-09-04 |
Family
ID=24435841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/003408 WO1997032129A1 (en) | 1996-02-28 | 1997-02-27 | Rapid infusion system |
Country Status (5)
Country | Link |
---|---|
US (1) | US5840068A (en) |
EP (1) | EP0827570A4 (en) |
CA (1) | CA2219663A1 (en) |
MX (1) | MX9708299A (en) |
WO (1) | WO1997032129A1 (en) |
Families Citing this family (45)
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US6328712B1 (en) * | 1996-02-28 | 2001-12-11 | Smisson-Cartledge Biomedical Corporation | Rapid infusion system |
US5879329A (en) * | 1997-01-22 | 1999-03-09 | Radiant Medical, Inc. | Infusion systems and methods for introducing fluids into the body within a desired temperature range |
US6824528B1 (en) | 1997-03-03 | 2004-11-30 | Medical Solutions, Inc. | Method and apparatus for pressure infusion and temperature control of infused liquids |
US6467953B1 (en) | 1999-03-30 | 2002-10-22 | Medical Solutions, Inc. | Method and apparatus for monitoring temperature of intravenously delivered fluids and other medical items |
US7287398B2 (en) * | 2001-09-25 | 2007-10-30 | Alsius Corporation | Heating/cooling system for indwelling heat exchange catheter |
US6554791B1 (en) * | 1999-09-29 | 2003-04-29 | Smisson-Cartledge Biomedical, Llc | Rapid infusion system |
US6464666B1 (en) * | 1999-10-08 | 2002-10-15 | Augustine Medical, Inc. | Intravenous fluid warming cassette with stiffening member and integral handle |
US6471674B1 (en) * | 2000-04-21 | 2002-10-29 | Medrad, Inc. | Fluid delivery systems, injector systems and methods of fluid delivery |
US6527743B1 (en) * | 2000-05-03 | 2003-03-04 | Ethicon Endo-Surgery, Inc. | Surgical system pump and method therefor |
US6899697B2 (en) * | 2000-05-03 | 2005-05-31 | Conmed Corp. | Surgical system pump and method therefor |
US6730267B2 (en) | 2001-02-09 | 2004-05-04 | Cardiovention, Inc. | Integrated blood handling system having active gas removal system and methods of use |
US6773670B2 (en) * | 2001-02-09 | 2004-08-10 | Cardiovention, Inc. C/O The Brenner Group, Inc. | Blood filter having a sensor for active gas removal and methods of use |
US7238171B2 (en) | 2001-03-12 | 2007-07-03 | Medical Solutions, Inc. | Method and apparatus for controlling pressurized infusion and temperature of infused liquids |
US6623470B2 (en) | 2001-06-27 | 2003-09-23 | Cleveland Clinic Foundation | Method and apparatus for controlling blood volume and hydration and for indicating resuscitation status of a patient using peripheral venous pressure as a hemodynamic parameter |
US8226605B2 (en) | 2001-12-17 | 2012-07-24 | Medical Solutions, Inc. | Method and apparatus for heating solutions within intravenous lines to desired temperatures during infusion |
US20030130624A1 (en) * | 2002-01-07 | 2003-07-10 | Kowalik Francis C. | Medical infusion system with integrated power supply and pump therefor |
US7022099B2 (en) * | 2003-03-17 | 2006-04-04 | Cardiovention, Inc. | Extracorporeal blood handling system with automatic flow control and methods of use |
US7611504B1 (en) | 2004-03-09 | 2009-11-03 | Patented Medical Solutions Llc | Method and apparatus for facilitating injection of medication into an intravenous fluid line while maintaining sterility of infused fluids |
US7608059B2 (en) * | 2004-05-25 | 2009-10-27 | Covidien Ag | Flow control apparatus |
US7975491B2 (en) * | 2005-03-17 | 2011-07-12 | Smisson-Cartledge Biomedical Llc | Heat exchange system for a pump device |
US7563248B2 (en) | 2005-03-17 | 2009-07-21 | Smisson-Cartledge Biomedical Llc | Infusion fluid heat exchanger and cartridge |
US7740611B2 (en) * | 2005-10-27 | 2010-06-22 | Patented Medical Solutions, Llc | Method and apparatus to indicate prior use of a medical item |
US8226293B2 (en) | 2007-02-22 | 2012-07-24 | Medical Solutions, Inc. | Method and apparatus for measurement and control of temperature for infused liquids |
US7927302B2 (en) * | 2007-04-24 | 2011-04-19 | Arizant Healthcare Inc. | High flow rate infusion unit and heat exchanger |
US9308307B2 (en) | 2007-09-13 | 2016-04-12 | Fresenius Medical Care Holdings, Inc. | Manifold diaphragms |
US8240636B2 (en) | 2009-01-12 | 2012-08-14 | Fresenius Medical Care Holdings, Inc. | Valve system |
US8597505B2 (en) | 2007-09-13 | 2013-12-03 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine |
US9358331B2 (en) | 2007-09-13 | 2016-06-07 | Fresenius Medical Care Holdings, Inc. | Portable dialysis machine with improved reservoir heating system |
US8105487B2 (en) | 2007-09-25 | 2012-01-31 | Fresenius Medical Care Holdings, Inc. | Manifolds for use in conducting dialysis |
US8062008B2 (en) | 2007-09-27 | 2011-11-22 | Curlin Medical Inc. | Peristaltic pump and removable cassette therefor |
US7934912B2 (en) | 2007-09-27 | 2011-05-03 | Curlin Medical Inc | Peristaltic pump assembly with cassette and mounting pin arrangement |
US8083503B2 (en) | 2007-09-27 | 2011-12-27 | Curlin Medical Inc. | Peristaltic pump assembly and regulator therefor |
CA2706919C (en) | 2007-11-29 | 2018-03-06 | Fresenius Medical Care Holdings, Inc. | System and method for conducting hemodialysis and hemofiltration |
CA2976872C (en) | 2008-10-07 | 2021-04-13 | Fresenius Medical Care Holdings, Inc. | Priming system and method for dialysis systems |
CA2739807C (en) | 2008-10-30 | 2017-02-28 | Fresenius Medical Care Holdings, Inc. | Modular, portable dialysis system |
US8608696B1 (en) * | 2009-02-24 | 2013-12-17 | North Carolina State University | Rapid fluid cooling devices and methods for cooling fluids |
WO2010114932A1 (en) | 2009-03-31 | 2010-10-07 | Xcorporeal, Inc. | Modular reservoir assembly for a hemodialysis and hemofiltration system |
CA2799775C (en) | 2010-06-04 | 2020-03-24 | Medrad, Inc. | System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors |
GB201021898D0 (en) * | 2010-12-23 | 2011-02-02 | Albalat Alberto M | Fluid circulation system |
US9211381B2 (en) | 2012-01-20 | 2015-12-15 | Medical Solutions, Inc. | Method and apparatus for controlling temperature of medical liquids |
US9201036B2 (en) | 2012-12-21 | 2015-12-01 | Fresenius Medical Care Holdings, Inc. | Method and system of monitoring electrolyte levels and composition using capacitance or induction |
US9157786B2 (en) | 2012-12-24 | 2015-10-13 | Fresenius Medical Care Holdings, Inc. | Load suspension and weighing system for a dialysis machine reservoir |
WO2014126964A1 (en) | 2013-02-15 | 2014-08-21 | Medical Solutions, Inc. | Plural medical item warming system and method for warming a plurality of medical items to desired temperatures |
US9354640B2 (en) | 2013-11-11 | 2016-05-31 | Fresenius Medical Care Holdings, Inc. | Smart actuator for valve |
EP3346913A4 (en) | 2015-09-25 | 2019-01-16 | C.R. Bard Inc. | Catheter assembly including monitoring capabilities |
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US4856972A (en) * | 1988-06-09 | 1989-08-15 | Fisher Scientific Co. | Dual roller peristaltic pump |
Family Cites Families (6)
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US4012177A (en) * | 1973-08-31 | 1977-03-15 | Yakich Sam S | Blood pump tube element |
US4747826A (en) * | 1983-06-08 | 1988-05-31 | University Of Pittsburgh | Rapid venous infusion system |
US4685902A (en) * | 1983-08-24 | 1987-08-11 | Becton, Dickinson And Company | Disposable reservoir cassette |
US4539005A (en) * | 1983-10-24 | 1985-09-03 | Greenblatt Gordon M | Blood infusion apparatus and method |
US5061241A (en) * | 1989-01-19 | 1991-10-29 | Stephens Jr Harry W | Rapid infusion device |
US4950136A (en) * | 1989-08-14 | 1990-08-21 | Hydro Systems Company | Peristaltic pump |
-
1996
- 1996-02-28 US US08/608,291 patent/US5840068A/en not_active Expired - Lifetime
-
1997
- 1997-02-27 CA CA002219663A patent/CA2219663A1/en not_active Abandoned
- 1997-02-27 WO PCT/US1997/003408 patent/WO1997032129A1/en not_active Application Discontinuation
- 1997-02-27 MX MX9708299A patent/MX9708299A/en unknown
- 1997-02-27 EP EP97908872A patent/EP0827570A4/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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US4856972A (en) * | 1988-06-09 | 1989-08-15 | Fisher Scientific Co. | Dual roller peristaltic pump |
Also Published As
Publication number | Publication date |
---|---|
EP0827570A1 (en) | 1998-03-11 |
MX9708299A (en) | 1998-04-30 |
EP0827570A4 (en) | 2001-07-04 |
US5840068A (en) | 1998-11-24 |
CA2219663A1 (en) | 1997-09-04 |
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