WO1998052478A1 - Cooling system for ultrasound device - Google Patents
Cooling system for ultrasound device Download PDFInfo
- Publication number
- WO1998052478A1 WO1998052478A1 PCT/US1998/010089 US9810089W WO9852478A1 WO 1998052478 A1 WO1998052478 A1 WO 1998052478A1 US 9810089 W US9810089 W US 9810089W WO 9852478 A1 WO9852478 A1 WO 9852478A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lead screw
- pusher block
- plunger
- syringe
- fluid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320069—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic for ablating tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320072—Working tips with special features, e.g. extending parts
- A61B2017/320073—Working tips with special features, e.g. extending parts probe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320084—Irrigation sleeves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320089—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic node location
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
Definitions
- the invention relates generally to a cooling system for an ultrasound
- a cooling system that includes a pump for delivering
- elongated ultrasound-transmitting probe that includes an ultrasound energy source, a
- remote locations within a patient must be sized to allow for easy maneuverability and
- regions of blood vessels, in particular the coronary arteries, are provided.
- ultrasound treatment system includes an energy source and an ultrasound probe that
- transmission member such as transmission wire, rod or both
- the transmission member having a proximal and distal end.
- the transmission member can be covered in
- the energy is transmitted to the distal end, which can include a tip, which in
- a guide catheter can be displaced in a longitudinal direction at the treatment site.
- the probe may also be provided such that the probe may be slidably disposed within the guide
- the transmission member can be partially contained within the sheathing that
- the guiding catheter can be connected to the outlet of a syringe by a conduit
- syringe pump so that fluid may be provided from the syringe by a syringe pump.
- a drive mechanism including a motor, gearing and a lead screw, and a pusher block that rides on the lead screw for pushing the plunger of a
- the drive mechanism can drive the pusher block, which pushes the plunger of
- the syringe which, in turn, provides fluid via the syringe outlet to the probe.
- the ultrasound treatment system may include a cooling system for
- the control system may include: a way to
- Another object of the invention is to provide an improved method for
- Yet another object of the invention is to provide an improved pump for
- the invention accordingly comprises the several steps and the relation of
- FIG. 1 is a perspective view of an ultrasound transmission system
- FIG. 2 is a perspective view of a cooling system constructed in
- FIG. 3 is a perspective view of a syringe pump type assembly
- FIG. 4 is a plan view of a drive mechanism of a syringe pump assembly
- FIG. 5 is a side view of an ultrasound transmission device constructed in
- FIG. 6 is an enlarged side view of a portion of the distal end of a
- FIG. 7 is a cross-sectional view of a locking mechanism, engaged with a
- FIG. 8 is a side view of a locking mechanism constructed in accordance
- FIG. 9 is a side view of the locking mechanism depicted in FIG. 8;
- FIG. 10 is a cross-sectional view taken along line 10-10, of the locking
- FIG. 11 is a cross-sectional view taken along line 11-11, of the locking
- FIG. 9 constructed in accordance with an embodiment of the invention.
- FIGS. 12A and 12B are cross-sectional views of a locking mechanism in
- FIGS. 13A and 13B are cross-sectional views of a locking mechanism in
- FIGS. 14A and 14B are cross-sectional views of a locking mechanism in
- FIGS. 15A and 15B are cross-sectional views of a locking mechanism in
- FIGS. 16A and 16B are cross-sectional views of a locking mechanism in
- FIG. 17 is a side view of a prior art transducer cable connector
- FIG. 18 is a side view of a transducer cable connector constructed in
- FIGS. 19A and 19B are cross-sectional views of a prior art half nut
- FIG. 20 is a schematic of a electronic control system constructed in
- occlusions and the like is to use an ultrasound probe to deliver ultrasound energy to a
- an ultrasound probe is provided.
- probe 200 illustrated generally as probe 200 in FIGS. 1, 5 and 6, and in a copending application
- Probe 200 is formed with a tapered horn 225, which includes a proximal
- proximal end 229 is preferably located at a displacement maximum relative to a standing ultrasound wave supported by the overall device. From proximal end 229,
- horn 225 tapers, in section A thereof, to a reduced diameter distal end 230, of diameter
- Proximal end 229 must be large enough to receive sufficient energy to
- in diameter is preferably accomplished in such a manner as to amplify the ultrasound
- Section C of probe 200 extends distally from transition zone B, and
- ultrasound device 200 operates in the
- resonant frequency mode i.e., it supports a standing wave when energized by
- ultrasound stimulation at proximal end 229, mass 250 is preferably located at a
- Section C may include multiple subsections having one or multiple
- section C may include a single transmission wire 240 that
- Transition zone D may include a
- transition zone D to support maximum stress, and, as such, transition zone D should be located at or near a displacement maximum (stress minimum).
- transition zone D may be located at a displacement node or anti-node or at
- a coolant such as water, saline or another fluid that
- the coolant can be introduced into a blood vessel.
- the coolant can be directed over and around
- the probe for example, by incorporating a sheath 245 (FIG. 6) around some or all
- Sheathing 245 may be affixed to the probe at one or more of the
- nodes of section A which are proximal transition section B.
- proximal transition section B One example of such an
- FIG. 1 Additional sheathing may be incorporated for
- Sheathing 245 is advantageously
- ultrasound device 200 are equally applicable to systems that promote or focus
- tissue hypothermia for cancer radiation therapy, for example.
- drugs for example.
- coolant fluid for cooling the ultrasound probe or delivered through a separate
- Horn 225 having a tapered section
- ultrasound energy is provided by a
- controller 815 Energy is supplied by a power source 246 via a coaxial cable 247 to a
- Transducer 249 is intimately connected to horn 225.
- Probe 200 also includes
- transmission member 240 coupled to horn 225 at the distal end of transition zone B
- tip 250 coupled to the distal end of transmission member 240.
- Tip 250 is coupled to three fine wires 260 by use of three openings in the
- Tip 250 may also be provided with an opening for a guidewire, and a guidewire tube may be installed in the opening and
- Fine wires 260 may be
- a gap 260' is advantageously provided between the
- Wire 240 may also be sheathed and that sheathing may be connected to the
- One known way of delivering a coolant to ultrasound probe 200 is to use
- a syringe pump-type device such as those typically used to infuse medication into a
- a syringe pump-type device generally includes a motor, a pusher
- the pusher block generally includes a half nut
- plunger which pushes fluid into an infusion line.
- a pusher block 334 includes a housing 390, which houses a half
- Half nut 305 is located below and substantially perpendicular
- Pusher block 334 also includes a push button 360, which is
- button 360 includes a shaft 361 and a cap 362.
- Pusher block 334 may be positioned along lead screw 310 by depressing
- half nut 305 moves along the thread of lead screw 310 until pusher block 334
- pusher block 334 becomes greater than the countering force of the syringe, pusher block 334 begins
- lead screw 310 When lead screw 310 begins turning, it exerts a normal force
- half nut "floats" so that the normal force may be reduced by shifting sideways, thereby
- slippage of the half nut on the lead screw can occur.
- One way to prevent slippage is to increase the spring force constant k of compression spring 320.
- spring force constant k of compression spring 320 is to increase the spring force constant k of compression spring 320.
- the spring made it more difficult for the user to manually position the pusher block.
- a cooling system generally indicated at 500,
- Cooling system 500 includes a housing 32, a controller 815, a syringe pump 30 for
- cooling system 500 When probe 200 is activated, cooling system 500 provides coolant to
- the transmission wire sections of probe 200 can quickly heat to a level
- housing 32 includes a display panel 79, a
- back panel 140 a back casing 141, a front casing 142, all of which can be formed of
- top casing 83 which is hinged to back panel 140 by
- Top casing 83 may be rotated about casing hinge 78 to expose
- Display panel 79 contains the operator control panel (not shown).
- Back panel 140 includes foot pedal plug 145 for receiving a foot pedal cable (not
- syringe pump 30 is contained within housing
- housing 32 includes a support 90 disposed within and supported by housing 32. As is,
- support 90 includes a top platform 91, a bottom platform 92,
- bottom platform 92 and top platform 91 bottom platform 92 and top platform 91.
- syringe 50 of pump 30 includes a
- barrel 52 having a distal end 204 with an outlet 55, and a proximal end 205, having a
- Syringe 50 also includes a plunger 54, having a proximal end 207, which
- proximal flange 56 has a proximal flange 56, and a distal end 206, which has a distal flange 206, sized to
- top platform 91 is divided into an upper portion 47 and a lower portion 48, which
- syringe 50 are joined by a hinge 49, and are releasably connected by a lockdown mechanism 51.
- Upper portion 47 can be pivoted about hinge 49 to permit barrel 52 of syringe 50 to be
- Syringe 50 is positioned in cradle 46 such that an upper
- flange 53 is not disposed within cradle 46. Rather an underside 53a of flange 53
- a drive mechanism 36 which includes a motor 40 having a shaft 41, coupled
- Pusher block 34 is guided by a first rail 80 and a second rail 81.
- First rail 80 First rail 80
- first upright 76 and second upright 77 are mounted at each end to first upright 76 and second upright 77.
- the speed of lead screw 44 is monitored by an encoder 39, mounted on upright 76,
- Lead screw 44 is axially supported by bearings (not shown), which in
- Reducer 42 which operatively couples lead screw 44 to motor 40 may include appropriately sized gears to reduce the speed of motor shaft 41 to an
- reducer 42 includes
- pusher block 34 includes a housing 66
- Wing 68 includes a T-bar 73 and a pusher block
- T-bar 73 is advantageously formed of plastic material which
- Housing 66 is
- housing 66 is generally cylindrical in shape at its upper one-third,
- top platform 91 to form a rectangular block shaped base 85.
- Housing 66 is bored to
- plug bore 87 which accommodates pusher block biasing assembly 62.
- biasing assembly 62 is held within housing 66 by lower plug 119.
- the upper third of housing 66 has two opposing slots 67 that permit T-bar 73 to be
- Wing 68 is supported on T-bar 73, which in turn is supported on slots 67
- housing 66 includes a first arm 71 on one side, a second arm 72 on the other
- First arm 71 is integrally connected with second
- Wing catch 74 includes a lower surface 74a and a notch
- Wing 68 may be formed of metal or a composite material, but preferably is
- Base 85 of housing 66 has a first bore 86 at one side thereof, a second
- housing 66 an in the same plane to provide stability to pusher block 34.
- bores
- 86, 88 and 89 are preferably spaced apart from one another along the same plane.
- bushings 86a and 88a disposed within bores 86 and 88 are bushings 86a and 88a,
- Bore 86 is further preferably formed of Teflon®, to minimize wear to base 85. Bore 86 is further
- tubing 86b preferably formed of bronze, to provide stability to pusher
- First bore 86 and second bore 88 are
- bushing 86a tubing 86b and first rail 80, and bushing
- Central bore 89 is sized to accommodate lead
- First rail 80 and second rail 81 are provided to ensure that pusher block 34
- pusher block 34 is made to
- housing 66 provides the
- Housing 66 also includes an antisiphon catch 65
- a pressure plate 35 which are integrally connected, preferably formed of a plastic
- Antisiphon catch 65 is V-shaped and is connected to
- Antisiphon catch 65 has a notch 64
- Wingcatch notch 74b is similarly configured to
- Pressure plate 35 is mounted on housing 66 so that when flange 56 is
- a force sensor 70 advantageously
- force sensor 70 includes a sensor button 70a, which is mounted on
- Force sensor 70 feeds an output signal to controller 815, which
- wing 68 is formed to overlap T-bar 73
- T-bar 73 includes a top portion 132, which is attached at its outer edges to wing 68 at
- first arm 71 and second arm 72 and a stem 133, which extends through slots 67 into
- T-bar 73 is preferably bolted to arms 71
- An upper plug 119 is formed in the shape of a cylinder, sized to fit within
- Upper plug 119 is preferably machined from bronze, and functions
- pusher block 34 includes push button 60, a plunger 110, having a plunger upper end
- Plunger 110 preferably is formed of bronze. Upper end 113 is connected to push
- Push button 60 is bored to accept an upper end of plunger spring 112.
- Push button 60 is preferably formed of aluminum, and has a shaft 63, which is bored to permit the
- plunger spring 112 occupies the space defined
- plunger actuator 114 within housing 66.
- FIGS. 10 and 11 In a preferred embodiment of the invention, shown in FIGS. 10 and 11,
- plunger 110 has a bore 125, having an upper edge 126 and a lower edge 127, and an
- bore 125 is threaded so that it can engage lead screw 44.
- compression spring 115 biases lower edge 127 against
- lead screw 44 be positioned along the length of lead screw 44.
- antisiphon catch 65 the user permits pusher block 34 to engage lead screw 44.
- FIGS. 1-10 An embodiment of the invention, shown at FIGS.
- 16A and 16B was designed employing some of the components of the conventional
- Locking mechanism 150 is preferably made of aluminum, and formed
- a pawl 103 having a tongue 101, an actuating portion 102, and a pawl spring
- Half nut 120 is threaded to mesh with lead screw 44, and notched at a notch 122
- Pawl spring 118 is connected to housing 66 so as to hinge pawl
- FIG. 16A which depicts locking mechanism 150
- locking mechanism 150 in an engaged position, locking mechanism 150 is spring-biased such that tongue 101
- Pusher block 34 is designed to
- Wing 68 is permitted to
- half nut 120 contacts
- plunger 1 10 is forced downward in a direction
- actuator 114 of plunger 110 contacts
- plunger 110 is permitted to contact half nut 120 and transmit the force
- antisiphon catch 65 the user pulls up on wing 68 in a direction shown as arrow X in
- FIG. 16B In this way, wing 68 travels upwardly in slots 67 acting against plunger
- the distance W is large enough to accommodate spring flange 56.
- plunger flange 56 is positioned within antisiphon catch 65.
- locking mechanism 150 can only be released if the user simultaneously presses down
- FIGS. 10 and 11 In a second embodiment of the invention, depicted at FIGS. 10 and 11,
- 16A and 16B is integral with plunger 110, and plunger 110 is maintained in its first
- This embodiment permits locking mechanism
- locking mechanism 100 includes a ball bearing 108, which is
- plunger 110 positioned within a channel 107 in housing 66 and a recess 109 in plunger 110.
- FIGS. 12A and 12B Pusher block 34 is in a first position where locking mechanism
- plunger 110 is able to move in the downward direction because ball bearing 108 no
- plunger 110 acts against and overcomes compression spring
- diameter of channel 107 is slightly greater than the diameter of ball bearing 108 and
- the outer diameter of channel 107 is slightly less than the diameter of ball bearing 108.
- FIGS. 14A and 14B another embodiment of a locking mechanism
- FIG. 14A depicts locking mechanism
- 14B depicts locking mechanism 450 in its unlocked position, where plunger 110 is
- Locking mechanism 450 includes a triangle-
- Bar 151 can be located anywhere along the length of plunger 110.
- Plunger 110 includes notch 152, which is
- Hinge 153 is connected to housing 66 and to one end of bar 151,
- middle portion 73 prevents
- this embodiment provides a novel structure that serves to lock pressure
- a locking mechanism 550 constructed
- FIG. 15A depicts
- FIG. 15B shows locking mechanism
- Locking mechanism 550 in an unlocked position.
- Locking mechanism 550 includes a latch 161, a notch
- Locking mechanism 550 is similar to locking
- hinge 163 biases latch 151 in a direction shown by an arrow S. Latch 161 is prevented
- portion 73 no longer retains latch 161. As such, latch 161 rotates away from plunger
- FIGS. 13A and 13B show a locking mechanism 650, constructed in
- FIG. 13 A depicts locking
- FIG. 13B shows locking mechanism 650 in a locked position
- Locking mechanism 650 includes a plurality of ball bearings
- an upper plug 619 formed with a wide diameter portion 620, a narrowed portion
- Upper plug 619 is preferably formed of bronze, and is sized to
- This embodiment differs from the other embodiments, as locking
- mechanism 650 is entirely contained within housing 66. That is, ball bearings 644 are
- FIG. 20 shows a schematic diagram of
- an electronic control system for controlling cooling system
- Electronic control system 800 monitors the functioning of
- control board 810 which is in turn
- controller 815 As is shown in FIG. 20, a pulse generator 870 is controlled
- Controller 815 instructs pulse generator
- pulses are sent to an output buffer 880 by a signal 871.
- Output buffer 880 receives signal 871 from pulse generator 870 and forwards this
- motor driver 890 drives motor 40 in a conventional manner
- controller 815 In addition to generating outputs for driving motor 40, controller 815,
- control board 810 collects inputs from three distinct sensor areas.
- drive mechanism 36 is depicted having
- Encoder 39 operatively coupled to the distal end of lead screw 44. Encoder 39 senses
- Counter 817 determines the relative movement that should
- signal 801 are forwarded to controller 815 as signal 802, which compares these two
- lead screw 44 is not moving as it should be, and that drive mechanism 36 could be
- controller 815 will shut down probe
- probe 200 may be operated without coolant fluid
- the controller can be
- the second sensor area includes force sensor 70 (noted above) which
- the controller may detect when syringe 50, conduit 98, or
- cooling system 500 monitors situations where the force or pressure is less than the lower force or pressure limit and situations where force or pressure is greater
- converter 830 receives this amplified analog
- the range of pressure may be defined based on the force detected by
- a user may identify the syringe size by inputting the syringe size into the user interface 148 on display panel 79 (FIG. 1). For a given
- the cross-sectional area of the barrel is known, and therefore knowing the
- probe 200 may be operated without coolant fluid delivery for a time
- the controller may sound an alarm
- the third sensor area includes sensors which are
- a first sensor 840 detects when
- a signal 806 is sent to an input buffer 860, which sends a signal 807 to
- controller 815 through control board 810 to warn controller 815 that the fluid level is
- pulse generator 870 is
- Signal 808 is also sent to controller 815 through control board 810 to
- Input buffer 860 comprises appropriate logic
- first and second signals 806 and 808 are properly sent to control board 810.
- controller 815 instructs
- Systems in accordance with the invention include a way to adjust the
- force sensor 70 may be fed to the controller so that the motor input signal may be
- coolant system 500 For example, in a preferred embodiment of the invention, syringe
- 50 is capable of delivering 60 ml of fluid.
- probe 200 requires 20 to 30 ml of fluid during the time the probe is activated.
- coolant delivery is enabled by controller 815 only during
- controller 815 signals motor 40 to drive syringe
- syringe plunger 54 is driven at about 33 psi
- motor 40 is energized to drive syringe
- fluid is provided at 1 ml/minute when probe 200 is in an idling mode.
- probe 200 is prevented from introducing air into a patient's vasculature when probe 200 is introduced into a patient's body and prevents blood from
- transducer connector 600 is depicted as connecting cable 602 to transducer 601.
- a connector in the prior art was an integral part of transducer 601. That is, cable 602
- transducer 601 was hard-wired to transducer 601. Because transducer 601 is screwed onto the
- Disconnect 700 is shown as releasable from transducer 701. In this manner, any twist
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55047998A JP2002515812A (en) | 1997-05-19 | 1998-05-15 | Cooling system for ultrasonic equipment |
EP98923469A EP0981298A4 (en) | 1997-05-19 | 1998-05-15 | Cooling system for ultrasound device |
AU75759/98A AU7575998A (en) | 1997-05-19 | 1998-05-15 | Cooling system for ultrasound device |
CA002290530A CA2290530A1 (en) | 1997-05-19 | 1998-05-15 | Cooling system for ultrasound device |
IL13287898A IL132878A0 (en) | 1997-05-19 | 1998-05-15 | Cooling system for ultrasound device |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4702297P | 1997-05-19 | 1997-05-19 | |
US08/858,247 | 1997-05-19 | ||
US60/047,022 | 1997-05-19 | ||
US08/858,247 US5971949A (en) | 1996-08-19 | 1997-05-19 | Ultrasound transmission apparatus and method of using same |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998052478A1 true WO1998052478A1 (en) | 1998-11-26 |
Family
ID=26724541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/010089 WO1998052478A1 (en) | 1997-05-19 | 1998-05-15 | Cooling system for ultrasound device |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0981298A4 (en) |
JP (1) | JP2002515812A (en) |
AU (1) | AU7575998A (en) |
CA (1) | CA2290530A1 (en) |
IL (1) | IL132878A0 (en) |
TW (1) | TW384227B (en) |
WO (1) | WO1998052478A1 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2493570A1 (en) * | 2009-10-26 | 2012-09-05 | Vytronus, Inc. | Methods and systems for ablating tissue |
US8475375B2 (en) | 2006-12-15 | 2013-07-02 | General Electric Company | System and method for actively cooling an ultrasound probe |
CN102078664B (en) * | 2009-11-27 | 2015-04-22 | 重庆融海超声医学工程研究中心有限公司 | Bandage type ultrasonic treatment device |
US20200215265A1 (en) * | 2016-06-17 | 2020-07-09 | Becton, Dickinson And Company | Method and Apparatus for Wetting Internal Fluid Path Surfaces of a Fluid Port to Increase Ultrasonic Signal Transmission |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4598706B2 (en) * | 2006-03-29 | 2010-12-15 | テルモ株式会社 | Initial blood collection device |
TWI733344B (en) * | 2020-02-21 | 2021-07-11 | 國立臺灣大學 | Ultrasonic device |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US47022A (en) | 1865-03-28 | Improvement in hand mowing-machines | ||
US3631847A (en) * | 1966-03-04 | 1972-01-04 | James C Hobbs | Method and apparatus for injecting fluid into the vascular system |
US3812843A (en) * | 1973-03-12 | 1974-05-28 | Lear Siegler Inc | Method and apparatus for injecting contrast media into the vascular system |
US4870953A (en) | 1987-11-13 | 1989-10-03 | Donmicheal T Anthony | Intravascular ultrasonic catheter/probe and method for treating intravascular blockage |
US4952205A (en) * | 1987-04-04 | 1990-08-28 | B. Braun Melsungen Ag | Pressure infusion device |
US5269297A (en) | 1992-02-27 | 1993-12-14 | Angiosonics Inc. | Ultrasonic transmission apparatus |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4424720A (en) * | 1980-12-15 | 1984-01-10 | Ivac Corporation | Mechanism for screw drive and syringe plunger engagement/disengagement |
GR1000159B (en) * | 1989-06-15 | 1991-10-10 | Micrel Kentro Efarm Mikroilekt | Syringe pump |
US5403324A (en) * | 1994-01-14 | 1995-04-04 | Microsonic Engineering Devices Company, Inc. | Flexible catheter with stone basket and ultrasonic conductor |
-
1998
- 1998-05-15 CA CA002290530A patent/CA2290530A1/en not_active Abandoned
- 1998-05-15 AU AU75759/98A patent/AU7575998A/en not_active Abandoned
- 1998-05-15 JP JP55047998A patent/JP2002515812A/en active Pending
- 1998-05-15 WO PCT/US1998/010089 patent/WO1998052478A1/en not_active Application Discontinuation
- 1998-05-15 EP EP98923469A patent/EP0981298A4/en not_active Withdrawn
- 1998-05-15 IL IL13287898A patent/IL132878A0/en unknown
- 1998-05-18 TW TW087107684A patent/TW384227B/en not_active IP Right Cessation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US47022A (en) | 1865-03-28 | Improvement in hand mowing-machines | ||
US3631847A (en) * | 1966-03-04 | 1972-01-04 | James C Hobbs | Method and apparatus for injecting fluid into the vascular system |
US3812843A (en) * | 1973-03-12 | 1974-05-28 | Lear Siegler Inc | Method and apparatus for injecting contrast media into the vascular system |
US4952205A (en) * | 1987-04-04 | 1990-08-28 | B. Braun Melsungen Ag | Pressure infusion device |
US4870953A (en) | 1987-11-13 | 1989-10-03 | Donmicheal T Anthony | Intravascular ultrasonic catheter/probe and method for treating intravascular blockage |
US5269297A (en) | 1992-02-27 | 1993-12-14 | Angiosonics Inc. | Ultrasonic transmission apparatus |
Non-Patent Citations (1)
Title |
---|
See also references of EP0981298A4 |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8475375B2 (en) | 2006-12-15 | 2013-07-02 | General Electric Company | System and method for actively cooling an ultrasound probe |
EP2493570A1 (en) * | 2009-10-26 | 2012-09-05 | Vytronus, Inc. | Methods and systems for ablating tissue |
CN102078664B (en) * | 2009-11-27 | 2015-04-22 | 重庆融海超声医学工程研究中心有限公司 | Bandage type ultrasonic treatment device |
US20200215265A1 (en) * | 2016-06-17 | 2020-07-09 | Becton, Dickinson And Company | Method and Apparatus for Wetting Internal Fluid Path Surfaces of a Fluid Port to Increase Ultrasonic Signal Transmission |
Also Published As
Publication number | Publication date |
---|---|
CA2290530A1 (en) | 1998-11-26 |
TW384227B (en) | 2000-03-11 |
JP2002515812A (en) | 2002-05-28 |
EP0981298A4 (en) | 2000-12-06 |
AU7575998A (en) | 1998-12-11 |
IL132878A0 (en) | 2001-03-19 |
EP0981298A1 (en) | 2000-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11490909B2 (en) | Systems and methods for removal of blood and thrombotic material | |
US11596437B2 (en) | Rotatable medical device | |
CN109152583B (en) | System and method for dissolving thrombus and delivering medicament | |
US9585686B2 (en) | Infusion flow guidewire system | |
US6206898B1 (en) | Rotational atherectomy device | |
US5344395A (en) | Apparatus for intravascular cavitation or delivery of low frequency mechanical energy | |
JP2020505114A (en) | Systems and methods for removing blood and thrombotic substances | |
EP1649817B1 (en) | Therapeutic ultrasound system | |
US6719718B2 (en) | Thrombectomy catheter and system | |
JP5178780B2 (en) | Ultrasound catheter for breaking vascular occlusion | |
JP2005537051A5 (en) | ||
EP1158910A1 (en) | Rotational atherectomy system with serrated cutting tip | |
JP2001087275A (en) | Rotary atelectomy system having side balloon | |
EP1092396B1 (en) | Crossflow thrombectomy catheter and system | |
EP0981298A1 (en) | Cooling system for ultrasound device | |
JP2012510859A (en) | System for enriching body fluids with gas with occlusion detection capability | |
JP2012510862A (en) | System for enriching body fluids with a gas having a removable gas enrichment device including an information recording element | |
CN109124727B (en) | In-tube longitudinal wave thrombus eliminator |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 132878 Country of ref document: IL |
|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 1998923469 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref document number: 2290530 Country of ref document: CA Ref document number: 2290530 Country of ref document: CA Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: 09424176 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 98806986.5 Country of ref document: CN |
|
WWP | Wipo information: published in national office |
Ref document number: 1998923469 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1998923469 Country of ref document: EP |