WO1999024097A1 - Intracranial bolt and method of placing and using an intracranial bolt to position a medical device - Google Patents

Intracranial bolt and method of placing and using an intracranial bolt to position a medical device Download PDF

Info

Publication number
WO1999024097A1
WO1999024097A1 PCT/US1998/002837 US9802837W WO9924097A1 WO 1999024097 A1 WO1999024097 A1 WO 1999024097A1 US 9802837 W US9802837 W US 9802837W WO 9924097 A1 WO9924097 A1 WO 9924097A1
Authority
WO
WIPO (PCT)
Prior art keywords
bore
bolt
medical device
skull
opening
Prior art date
Application number
PCT/US1998/002837
Other languages
French (fr)
Inventor
Michael A. Lawson
Peter R. Werp
Willian Penny
Walter M. Blume
Original Assignee
Stereotaxis, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stereotaxis, Inc. filed Critical Stereotaxis, Inc.
Priority to AU63257/98A priority Critical patent/AU6325798A/en
Publication of WO1999024097A1 publication Critical patent/WO1999024097A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M39/0613—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof with means for adjusting the seal opening or pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M27/006—Cerebrospinal drainage; Accessories therefor, e.g. valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B2090/103—Cranial plugs for access to brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/062—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof used with a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/0673—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof comprising means actively pressing on the device passing through the seal, e.g. inflatable seals, diaphragms, clamps

Definitions

  • This invention relates to an intracranial bolt for placement in an opening in the skull to provide access to the brain, and to a method of placing and using the intracranial bolt to position a medical device in the brain.
  • the intracranial bolt of the present invention can be placed in an opening in the skull to provide access to the brain.
  • the intracranial bolt has a proximal end and a distal end adapted for placement in an opening in the sl ill, and a bore extending between the proximal end and the distal end for the passage of a medical device.
  • a removable cap can be provided for the distal end of the bolt to close the distal end of the bore.
  • an inflatable member in the bore which, when inflated, engages a medical device in the bore releasably anchoring the device within the bore.
  • the inflatable member preferably comprises a flexible liner in the bore, that defines a pocket between the liner and bore, and a passage through the bolt to the pocket for filling the pocket with a fluid to urge the liner radially inwardly to constrict the bore and engage a medical device therein.
  • the intracranial bolt can be placed in the skull in a sterile environment, such as a procedure or an operating room.
  • An opening is made in the skull, and the distal end of the intracranial bolt is placed in the opening.
  • a removable cap can be secured over the proximal end to close the proximal end of the bore.
  • the patient can then be moved out of the sterile environment of the procedure or operating room, to other locations, for example where there is magnetic field generating equipment for positioning medical devices introduced through the intracranial bolt, or where there is x-ray or magnetic resonance imaging equipment for monitoring a procedure being conducted with medical devices extending through the intracranial bolt.
  • the device can be secured, either during the procedure, or between procedures, by inflating the inflatable member in the bore.
  • the intracranial bolt prevents undesired movement of the device during the procedure, and/or undesired movement of the device between procedures. This allows, for example, a catheter to be placed through the intracranial bolt and positioned into the brain and held in place for guiding diagnostic or therapeutic devices to a particular location in the brain.
  • the inflatable member can be partially or fully deflated.
  • a medical device can be held in place in the bore, and the proximal end of the intracranial bolt can be closed with the cap.
  • the medical device remains securely in place, anchored by the inflatable member, until the procedure is continued.
  • the intracranial bolt of the present invention provides convenient access to the brain for diagnostic and therapeutic procedures. After installation, the bolt provides controlled sterile access, even in non-sterile environments, allowing the use of specialized equipment that is not practically available in a sterile operating room.
  • the intracranial bolt is capable of securely temporarily anchoring a medial device extending through it during and between procedures, but does not damage the medical device.
  • Fig. 1 is an elevational view of an intracranial bolt constructed according to the principles of this invention
  • Fig. 2 is an elevational view of the intracranial bolt taken from the right side as shown in Fig. 1 ;
  • Fig. 3 is a front plan view of the intracranial bolt
  • Fig. 4 is a rear plan view of the intracranial bolt
  • Fig. 5 is an enlarged cross-sectional view of the intracranial bolt, shown as it would be placed in an opening in a skull;
  • Fig. 6 is an enlarged cross-sectional view of the intracranial bolt, shown with the inflatable member inflated to secure a medical device in the bore of the intracranial bolt;
  • Fig. 7 is a schematic view of a catheter system that could be used with the intracranial bolt.
  • the intracranial bolt 20 is adapted to be secured in an opening in the skull.
  • the intracranial bolt 20 comprises a body 22 having a front or distal end 24 (see Fig. 3) and a rear or proximal end 26, with a bore 28 extending through the body between the proximal and distal ends.
  • the body 22 is preferably made of a plastic material such as polycarbonate, that is not affected by magnetic fields, and is transparent to x-ray and magnetic imaging techniques.
  • the front or distal end 24 of the body 22 has a generally cylindrical extension 30, with external threads 32 for securing the intracranial bolt in a burr hole fonned in the slcull.
  • the rear or proximal end 26 of the body 22 has a generally cylindrical stem 34, having a raised circumferential lip 36 thereon, and a circumferential groove 38 therein for mounting a resilient o-ring 40.
  • the o-ring 40 seals with, and the lip 32 helps secure, a removable cap 42 for closing the proximal end of the bore 28.
  • the cap preferably includes a socket 43 for mounting a marker 45.
  • the marker 45 is preferably a hollow body that can be filled with a substance, such as vitamin e, that is opaque (but non-distorting) to magnetic resonance imaging.
  • the marker provides a clear indication of the location and orientation of the intracranial bolt, which is otherwise transparent to magnetic resonance imaging, so that in a pre-procedure magnetic resonance image, the path of the medical instrument through the intracranial bolt and into the brain can be planned in advance.
  • the inflatable member 44 in the bore 28 which, when inflated, engages and secures a medical device extending through the bore.
  • the inflatable member 44 comprises a flexible panel 46 lining at least a portion of the bore 28, and forming a pocket 48 therebetween, and more preferably the flexible panel is cylindrical, lining the entire circumference of the bore 28 for at least a portion of its length.
  • the first and second edges 50 and 52 of the flexible panel are secured to the wall of the bore 28 with adhesive. Rings 54 and 56 can be placed in the bore to further secure then edges of the panel against the wall of the bore.
  • a passage 58 extends through the body 22 to the pocket 48 formed between the wall of the bore 28 and the panel 46.
  • a syringe fitting 60 is attached to the end of the passage 58.
  • the fitting 60 is adapted to receive a syringe S (Fig. 6) so that fluid can be injected into the pocket 48 to urge the panel 46 radially inwardly into the bore 28 to engage a medical device, such as a catheter C, extending through the bore.
  • the inflatable member 44 preferably engages the medical device with sufficient force to prevent unintentional movement of the device, thereby functioning as an anchor or clamp.
  • an incision is made in the scalp to expose the skull, and a burr hole is made in the skull.
  • the intracranial bolt 20 is installed in the burr hole by threading the threads 32 into the burr hole.
  • the bore 28 through the intracranial bolt provides access to the interior of the skull.
  • the cap 42 can be secured on the stem 34, thereby sealing the bore 28 (and the access to the interior of the skull).
  • the installation of the intracranial bolt is preferably done in a sterile environment, such as a procedure or an operating room, but after the intracranial bolt is installed, it can provide sterile access to the interior of the skull in any environment.
  • the patient can be moved to another site, for example an x-ray or magnetic resonance imaging facility, or a site equipped with magnetic field generating equipment for introducing and guiding magnetic medical devices inside the skull. It is impractical to have such equipment in a sterile operating room environment, but the intracranial bolt provides sterile access to the interior of the skull for conducting medical procedures using such equipment in a non-sterile environment.
  • another site for example an x-ray or magnetic resonance imaging facility, or a site equipped with magnetic field generating equipment for introducing and guiding magnetic medical devices inside the skull.
  • the intracranial bolt 20 can remain in place to provide repeated access during a course of treatment. Moreover, the intracranial bolt 20 can clamp or anchor medical devices both during and between medical procedures. For example in a diagnostic or therapeutic procedure it might be desirable to introduce a catheter into the skull. The catheter can pass easily into the skull through the bore 28 of the intracranial bolt 20. Once the catheter is in its desired position, the inflatable member 44 can be inflated to secure the catheter in the bore. More specifically, a syringe S can be mounted onto fitting 60 and inject fluid, such as air or saline solution, into the pocket 48 between the liner 46 and the wall of the bore 28. The fluid urges the liner 46 radially inwardly to engage the catheter C (or other medical device) in the bore 28, securing the catheter against inadvertent movement.
  • fluid such as air or saline solution
  • the catheter C can he held in place, and the intracranial bolt 20 capped with cap 42 so that the catheter can be used for repeated access to the interior of the skull.
  • the catheter could be used as an access for taking biopsies, and left in place pending testing of the biopsies, for the administration of therapy.
  • a course of therapy might require repeated delivery of medications to the same area, and the catheter can be held in place during the course of treatment.
  • the intracranial bolt 20 is conveniently used with the catheter system 100.
  • An outer sheath 102 is secured to the intracranial bolt 20.
  • the outer sheath 102 contains a "Y" 104 that splits the outer sheath into first and second branches 106 and 108.
  • At the end of the first branch 106 of the outer sheath 102 is an expandable sheath 110.
  • the expandable sheath 110 clamps over a guide wire G, and allows the movement of the guide wire in the outer sheath 102.
  • the expandable sheath 110 comprises proximal and distal connectors 112 and 114, which are secured in a motor-driven mechanical drive system under the surgeon's control.
  • the drive system advances the proximal connector 112 while holding the distal connector 114 stationary to move the guide wire.
  • a catheter C is mounted over the distal end of the guide wire G, and is advanced through the intracranial bolt 20 with the advancement of the guide wire.
  • the second branch 108 terminates in an access port 116. After the catheter C is properly positioned, the intracranial bolt is operated to secure the catheter, and with the catheter secured, the guide wire can withdrawn past the "Y" 104.
  • the access port 116 is opened, and an medical device, for example a biopsy tool, can be introduced through the branch 108 and into the catheter C, and through the catheter C into the brain.
  • the intracranial bolt of the present invention provides sterile access to the interior of the skull, even in non sterile environments. Furthermore, in the preferred embodiment, the intracranial bolt can secure medical devices in place, during and/or between medical procedures.

Abstract

An intracranial bolt, for installation in an opening in the skull to provide access to the brain for a medical device, has a bore (28) for the passage of the medical device, and an inflatable member (44) in the bore which when inflated engages a medical device in the bore, releasably anchoring the device. The inflatable member comprises a cylinder of flexible sheet material and is secured to the wall of the bore defining a pocket (48). A passage (58) extends through the bolt to the pocket for the introduction of fluid into the pocket to expand the inflatable member radially inwardly. The bolt is used by forming an opening in the skull; installing the bolt in the opening; and securing a cap (42) on the bolt. The cap can be removed and a medical device can be inserted through the bolt. The inflatable member can be inflated to hold the medical device in place.

Description

INTRACRANIAL BOLT
AND METHOD OF PLACING .AND USING
AN INTRACRANIAL BOLT TO POSITION A MEDICAL DEVICE
FIELD OF THE INVENTION
This invention relates to an intracranial bolt for placement in an opening in the skull to provide access to the brain, and to a method of placing and using the intracranial bolt to position a medical device in the brain.
BACKGROUND OF THE INVENTION
There are instances where it is desirable to have a sterile access to the brain for conducting a diagnostic or therapeutic procedure in a non-sterile environment. For example, techniques have been developed to position medical devices in the brain using an externally applied magnetic field. These techniques are most conveniently employed in a non-sterile environment where the equipment is available for generating the appropriate magnetic field. Similarly, it is often desirable to monitor a procedure with x-ray or magnetic resonance imaging equipment that is available only in non-sterile environments. There are also situations where repeated access to the brain is needed to complete a diagnostic or therapeutic procedure, but it is undesirable to perform repeated surgeries each time access is required.
It is also desirable to be able to releasably anchor medical devices inserted in to the body to prevent unintentional movement during a medical procedure, or to allow a medical device to remain in place between medical procedures, rather than reinserting the medical device at the start of each procedure.
SUMM^Y OF THE INVENTION
The intracranial bolt of the present invention can be placed in an opening in the skull to provide access to the brain. The intracranial bolt has a proximal end and a distal end adapted for placement in an opening in the sl ill, and a bore extending between the proximal end and the distal end for the passage of a medical device. A removable cap can be provided for the distal end of the bolt to close the distal end of the bore.
In the preferred embodiment of the invention, there is an inflatable member in the bore which, when inflated, engages a medical device in the bore releasably anchoring the device within the bore. In the manner the intracranial bolt functions like a clamp, releasably securing a medical device without damaging it. The inflatable member preferably comprises a flexible liner in the bore, that defines a pocket between the liner and bore, and a passage through the bolt to the pocket for filling the pocket with a fluid to urge the liner radially inwardly to constrict the bore and engage a medical device therein. According to the method of this invention, the intracranial bolt can be placed in the skull in a sterile environment, such as a procedure or an operating room. An opening is made in the skull, and the distal end of the intracranial bolt is placed in the opening. A removable cap can be secured over the proximal end to close the proximal end of the bore. Thus sealed, the patient can then be moved out of the sterile environment of the procedure or operating room, to other locations, for example where there is magnetic field generating equipment for positioning medical devices introduced through the intracranial bolt, or where there is x-ray or magnetic resonance imaging equipment for monitoring a procedure being conducted with medical devices extending through the intracranial bolt.
With the intracranial bolt of the preferred embodiment, once a medical device has been properly placed through the bolt and into the brain, the device can be secured, either during the procedure, or between procedures, by inflating the inflatable member in the bore. The intracranial bolt prevents undesired movement of the device during the procedure, and/or undesired movement of the device between procedures. This allows, for example, a catheter to be placed through the intracranial bolt and positioned into the brain and held in place for guiding diagnostic or therapeutic devices to a particular location in the brain. When it is desired to move or remove the catheter or other medical device, the inflatable member can be partially or fully deflated.
For procedures where repeated access is required, a medical device can be held in place in the bore, and the proximal end of the intracranial bolt can be closed with the cap. The medical device remains securely in place, anchored by the inflatable member, until the procedure is continued.
Thus the intracranial bolt of the present invention provides convenient access to the brain for diagnostic and therapeutic procedures. After installation, the bolt provides controlled sterile access, even in non-sterile environments, allowing the use of specialized equipment that is not practically available in a sterile operating room. The intracranial bolt is capable of securely temporarily anchoring a medial device extending through it during and between procedures, but does not damage the medical device. These and other features and advantages will be in part apparent, and in part pointed out hereinafter.
BMEF DESCRIPTION OF THE DRAWINGS
Fig. 1 is an elevational view of an intracranial bolt constructed according to the principles of this invention;
Fig. 2 is an elevational view of the intracranial bolt taken from the right side as shown in Fig. 1 ;
Fig. 3 is a front plan view of the intracranial bolt;
Fig. 4 is a rear plan view of the intracranial bolt;
Fig. 5 is an enlarged cross-sectional view of the intracranial bolt, shown as it would be placed in an opening in a skull;
Fig. 6 is an enlarged cross-sectional view of the intracranial bolt, shown with the inflatable member inflated to secure a medical device in the bore of the intracranial bolt; and
Fig. 7 is a schematic view of a catheter system that could be used with the intracranial bolt.
Corresponding reference numerals indicate corresponding parts throughout the several views of the drawings. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
An intracranial bolt constructed according to the principles of the present invention is indicated generally as 20 in the figures. The intracranial bolt 20 is adapted to be secured in an opening in the skull. The intracranial bolt 20 comprises a body 22 having a front or distal end 24 (see Fig. 3) and a rear or proximal end 26, with a bore 28 extending through the body between the proximal and distal ends. The body 22 is preferably made of a plastic material such as polycarbonate, that is not affected by magnetic fields, and is transparent to x-ray and magnetic imaging techniques.
The front or distal end 24 of the body 22 has a generally cylindrical extension 30, with external threads 32 for securing the intracranial bolt in a burr hole fonned in the slcull. The rear or proximal end 26 of the body 22 has a generally cylindrical stem 34, having a raised circumferential lip 36 thereon, and a circumferential groove 38 therein for mounting a resilient o-ring 40. The o-ring 40 seals with, and the lip 32 helps secure, a removable cap 42 for closing the proximal end of the bore 28.
The cap preferably includes a socket 43 for mounting a marker 45. The marker 45 is preferably a hollow body that can be filled with a substance, such as vitamin e, that is opaque (but non-distorting) to magnetic resonance imaging. The marker provides a clear indication of the location and orientation of the intracranial bolt, which is otherwise transparent to magnetic resonance imaging, so that in a pre-procedure magnetic resonance image, the path of the medical instrument through the intracranial bolt and into the brain can be planned in advance.
There is preferably an inflatable member 44 in the bore 28 which, when inflated, engages and secures a medical device extending through the bore. In the preferred embodiment, the inflatable member 44 comprises a flexible panel 46 lining at least a portion of the bore 28, and forming a pocket 48 therebetween, and more preferably the flexible panel is cylindrical, lining the entire circumference of the bore 28 for at least a portion of its length. The first and second edges 50 and 52 of the flexible panel are secured to the wall of the bore 28 with adhesive. Rings 54 and 56 can be placed in the bore to further secure then edges of the panel against the wall of the bore.
A passage 58 extends through the body 22 to the pocket 48 formed between the wall of the bore 28 and the panel 46. A syringe fitting 60 is attached to the end of the passage 58. The fitting 60 is adapted to receive a syringe S (Fig. 6) so that fluid can be injected into the pocket 48 to urge the panel 46 radially inwardly into the bore 28 to engage a medical device, such as a catheter C, extending through the bore. The inflatable member 44 preferably engages the medical device with sufficient force to prevent unintentional movement of the device, thereby functioning as an anchor or clamp.
OPERATION
In operation, an incision is made in the scalp to expose the skull, and a burr hole is made in the skull. The intracranial bolt 20 is installed in the burr hole by threading the threads 32 into the burr hole. The bore 28 through the intracranial bolt provides access to the interior of the skull. After the intracranial bolt 20 is secured in the burr hole, the cap 42 can be secured on the stem 34, thereby sealing the bore 28 (and the access to the interior of the skull). The installation of the intracranial bolt is preferably done in a sterile environment, such as a procedure or an operating room, but after the intracranial bolt is installed, it can provide sterile access to the interior of the skull in any environment. More specifically, after installation of the intracranial bolt 20 the patient can be moved to another site, for example an x-ray or magnetic resonance imaging facility, or a site equipped with magnetic field generating equipment for introducing and guiding magnetic medical devices inside the skull. It is impractical to have such equipment in a sterile operating room environment, but the intracranial bolt provides sterile access to the interior of the skull for conducting medical procedures using such equipment in a non-sterile environment.
The intracranial bolt 20 can remain in place to provide repeated access during a course of treatment. Moreover, the intracranial bolt 20 can clamp or anchor medical devices both during and between medical procedures. For example in a diagnostic or therapeutic procedure it might be desirable to introduce a catheter into the skull. The catheter can pass easily into the skull through the bore 28 of the intracranial bolt 20. Once the catheter is in its desired position, the inflatable member 44 can be inflated to secure the catheter in the bore. More specifically, a syringe S can be mounted onto fitting 60 and inject fluid, such as air or saline solution, into the pocket 48 between the liner 46 and the wall of the bore 28. The fluid urges the liner 46 radially inwardly to engage the catheter C (or other medical device) in the bore 28, securing the catheter against inadvertent movement.
The catheter C can he held in place, and the intracranial bolt 20 capped with cap 42 so that the catheter can be used for repeated access to the interior of the skull. For example, the catheter could be used as an access for taking biopsies, and left in place pending testing of the biopsies, for the administration of therapy. Alternatively, a course of therapy might require repeated delivery of medications to the same area, and the catheter can be held in place during the course of treatment.
As shown in Fig. 7, the intracranial bolt 20 is conveniently used with the catheter system 100. An outer sheath 102 is secured to the intracranial bolt 20. The outer sheath 102 contains a "Y" 104 that splits the outer sheath into first and second branches 106 and 108. At the end of the first branch 106 of the outer sheath 102 is an expandable sheath 110. The expandable sheath 110 clamps over a guide wire G, and allows the movement of the guide wire in the outer sheath 102. The expandable sheath 110 comprises proximal and distal connectors 112 and 114, which are secured in a motor-driven mechanical drive system under the surgeon's control. The drive system advances the proximal connector 112 while holding the distal connector 114 stationary to move the guide wire. A catheter C is mounted over the distal end of the guide wire G, and is advanced through the intracranial bolt 20 with the advancement of the guide wire. The second branch 108 terminates in an access port 116. After the catheter C is properly positioned, the intracranial bolt is operated to secure the catheter, and with the catheter secured, the guide wire can withdrawn past the "Y" 104. The access port 116 is opened, and an medical device, for example a biopsy tool, can be introduced through the branch 108 and into the catheter C, and through the catheter C into the brain.
Thus the intracranial bolt of the present invention provides sterile access to the interior of the skull, even in non sterile environments. Furthermore, in the preferred embodiment, the intracranial bolt can secure medical devices in place, during and/or between medical procedures.

Claims

What is claimed:
1. A clamp for releasably anchoring a medical device extending through an opening in a skull, the clamp comprising a body adapted to be secured in the opening in the skull, the body having a bore therethrough for the passage of the medical device, and an inflatable member in the bore which when inflated engages the medical device in the bore, releasably anchoring the device.
2. The clamp of claim 1 wherein the body is shaped to abut substantially the entire circumference of the opening, and the bore extends through the body and is itself surrounded by the body.
3. The clamp according to claim 1 wherein the inflatable member comprises a panel of flexible sheet material secured to the wall of the bore, and wherein there is a passage through the body, opening in the wall of the bore underneath the panel for introducing a fluid under the panel to cause the panel to extend into the bore.
4. The clamp according to claim 3 wherein the panel is generally cylindrical.
5. A clamp for releasably anchoring a medical device extending through an opening in the skull, the clamp comprising: a body adapted to be secured in the opening in the skull, the body having a bore therethrough for the passage of the medical device; a panel of flexible sheet material secured to the wall of the bore to form a pocket between the panel and the wall, and a passage through the body communicating with the pocket; the panel expanding radially inwardly into the bore upon the introduction of fluid into the pocket to engage a medical device in the bore and releasably anchor the device.
6. The clamp of claim 5 wherein the body is shaped to abut substantially the entire circumference of the opening, and the bore extends through the body and is itself surrounded by the body.
7. The clamp according to claim 5 wherein the panel is generally cylindrical, having first and second ends, and wherein the panel is secured to the wall of the bore adjacent its first and second ends.
8. A clamp for installation in a bore in a skull to releasably anchor a medical device extending into the brain, the clamp having a bore therethrough for the medical device, and an inflatable member in the bore for engaging the medical device in the bore and releasably anchoring the device.
9. The claim of claim 8 wherein the clamp is shaped to abut substantially the entire circumference of the skull bore, and the clamp bore extends through the clamp and is itself surrounded by the clamp.
10. An intracranial bolt for installation in an opening in a skull to provide access to a brain for a medical device, the bolt having a bore therethrough for the passage of the medical device, and an inflatable member in the bore which when inflated engages a medical device in the bore, releasably anchoring the device.
11. The intracranial bolt of claim 10 wherein the bolt is shaped to abut substantially the entire circumference of the opening, and the bore extends through the bolt and is itself surrounded by the bolt.
12. The intracranial bolt according to claim 10 wherein the inflatable member extends around the circumference of the bore, and upon inflation expands radially inwardly into the bore.
13. The intracranial bolt according to claim 12 wherein the inflatable member comprises a cylinder of flexible sheet material inside the bore, the cylinder having first and second end, and being secured to the wall of the bore at the first and second ends, the cylinder and wall of the bore defining an annular pocket therebetween, the cylinder expanding radially inwardly into the bore upon the introduction of fluid into the pocket.
14. The intracranial bolt according to claim 10 wherein the inflatable member comprises an annular balloon in the bore through which the medical device extends.
15. The intracranial bolt according to claim 10 wherein the inflatable member is foraied by the wall of the bore and a panel of flexible material extending around the circumference of the bore.
16. An intracranial bolt for installation in an opening in a skull to provide access to a brain for a medical device, the bolt having a distal portion adapted to be secured in the opening the skull, and a proximal portion adapted to project from the skull when the bolt is installed in the opening, and a bore extending between the proximal and distal sections, the proximal portion adapted to sealingly receive a cap for closing the proximal end of the bore.
17. The intracranial bolt of claim 16 wherein the bolt is shaped to abut substantially the entire circumference of the opening, and the bore extends through the bolt and is itself surrounded by the bolt.
18. The intracranial bolt according to claim 16 further comprising an inflatable member in the bore which, when inflated, expands in the bore to engage a medical device in the bore.
19. The intracranial bolt according to claim 18 wherein the inflatable member comprises a panel of flexible material secured over the wall of the bore to form a pocket therebetween, and a passage through the bolt communicating with the pocket for introducing fluid into the pocket to urge the panel away from the wall and into the pocket.
20. The intracranial bolt according to claim 19 wherein the panel extends circumferentially around the bore.
21. A method of performing a medical procedure on the brain comprising:
forming an opening in the skull;
installing an intracranial bolt in the opening in the skull, the intracranial bolt having a distal portion adapted to be secured in the opening in the skull, a proximal portion adapted to project from the skull when the bolt is installed in the opening, and a bore extending between the proximal and distal sections for providing access to the brain through the bolt;
securing a cap on the proximal end of the bolt; and
removing the cap after installation of the bolt and inserting a medical device through the bore in the bolt to perform a medical procedure on the brain.
22. The method according to claim 21 wherein the step of inserting a medical device through the bore in the bolt comprises inserting a cannula through the bore and into the brain to provide a pathway; and further comprising the step of replacing the cap on the bolt after the installation of the cannula.
23. A method of placing and temporarily anchoring a medical device through a skull and into a brain, the method comprising:
forming an opening in the skull;
installing an intracranial bolt in the opening in the skull, the bolt having a bore therethrough for the passage of a medical device, and an inflatable member in the bore which when inflated engages a medical device in the bore;
inserting a medical device through the bore of the bolt and into the brain; and
inflating the inflatable member to engage the device, and releasably anchor the device.
24. The method according to claim 23, wherein the bolt is adapted to mount a cap, and further comprising the step of securing a cap on the bolt after the medical device has been inserted into the bore.
25. The method according to claim 23 wherein the inflatable member comprises a panel of flexible sheet material secured over a portion of the wall of the bore to foim a pocket between the panel and wall, and wherein the step of inflating the inflatable member comprises introducing fluid into the pocket to urge the flexible panel away from the wall and into the bore to engage the medical device in the bore.
26. The method according to claim 25 wherein the panel extends circumferentially around the wall of the bore.
PCT/US1998/002837 1997-11-12 1998-02-17 Intracranial bolt and method of placing and using an intracranial bolt to position a medical device WO1999024097A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU63257/98A AU6325798A (en) 1997-11-12 1998-02-17 Intracranial bolt and method of placing and using an intracranial bolt to position a medical device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6510897P 1997-11-12 1997-11-12
US60/065,108 1997-11-12

Publications (1)

Publication Number Publication Date
WO1999024097A1 true WO1999024097A1 (en) 1999-05-20

Family

ID=22060392

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/002837 WO1999024097A1 (en) 1997-11-12 1998-02-17 Intracranial bolt and method of placing and using an intracranial bolt to position a medical device

Country Status (3)

Country Link
US (1) US6152933A (en)
AU (1) AU6325798A (en)
WO (1) WO1999024097A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002007811A1 (en) * 2000-07-25 2002-01-31 Csf Dynamics A/S A ventricle drain
US6905474B2 (en) 2000-09-11 2005-06-14 Csf Dynamic A/S Fluid shunt system and a method for the treatment of hydrocephalus
US7118548B2 (en) 1996-09-18 2006-10-10 Sinu Shunt A/S Device for the treatment of hydrocephalus
CN100506314C (en) * 2005-07-04 2009-07-01 中国科学院心理研究所 Implanted intracranial administration intubate suitable for neuroscience research
WO2019219784A1 (en) 2018-05-17 2019-11-21 National University Of Ireland, Galway A valved introducer sheath

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7066924B1 (en) * 1997-11-12 2006-06-27 Stereotaxis, Inc. Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip
US6505062B1 (en) * 1998-02-09 2003-01-07 Stereotaxis, Inc. Method for locating magnetic implant by source field
DE19822711B4 (en) * 1998-05-20 2006-11-23 Disetronic Licensing Ag Sensor system with port body
US6945955B1 (en) * 1998-05-20 2005-09-20 Disetronic Licensing Ag Sensor system including a port body
US6482182B1 (en) * 1998-09-03 2002-11-19 Surgical Navigation Technologies, Inc. Anchoring system for a brain lead
GB9821575D0 (en) * 1998-10-02 1998-11-25 Diametrics Medical Limited Cranial bolt
US7553290B1 (en) * 1999-06-04 2009-06-30 Medtronic Ps Medical, Inc. Subdural evacuating port aspiration system
US7313429B2 (en) 2002-01-23 2007-12-25 Stereotaxis, Inc. Rotating and pivoting magnet for magnetic navigation
US6702804B1 (en) 1999-10-04 2004-03-09 Stereotaxis, Inc. Method for safely and efficiently navigating magnetic devices in the body
US6401723B1 (en) * 2000-02-16 2002-06-11 Stereotaxis, Inc. Magnetic medical devices with changeable magnetic moments and method of navigating magnetic medical devices with changeable magnetic moments
US7766856B2 (en) 2001-05-06 2010-08-03 Stereotaxis, Inc. System and methods for advancing a catheter
US7276044B2 (en) 2001-05-06 2007-10-02 Stereotaxis, Inc. System and methods for advancing a catheter
US7635342B2 (en) * 2001-05-06 2009-12-22 Stereotaxis, Inc. System and methods for medical device advancement and rotation
US7587234B2 (en) * 2001-11-02 2009-09-08 Abbott Cardiovascular Systems Inc. Method and apparatus for computer modified magnetic resonance imaging
US20040092810A1 (en) * 2002-02-14 2004-05-13 Wolfgang Daum Method and apparatus for MR-guided biopsy
US8123697B2 (en) * 2002-02-14 2012-02-28 Koninklijke Philips Electronics N.V. Method and apparatus for MR-guided biopsy
US7248914B2 (en) 2002-06-28 2007-07-24 Stereotaxis, Inc. Method of navigating medical devices in the presence of radiopaque material
US7390310B2 (en) * 2002-07-10 2008-06-24 Codman & Shurtleff, Inc. Shunt valve locking mechanism
US7769427B2 (en) 2002-07-16 2010-08-03 Magnetics, Inc. Apparatus and method for catheter guidance control and imaging
AU2003295741A1 (en) 2002-11-18 2004-06-15 Stereotaxis, Inc. Magnetically navigable balloon catheters
US7389778B2 (en) 2003-05-02 2008-06-24 Stereotaxis, Inc. Variable magnetic moment MR navigation
US6980843B2 (en) * 2003-05-21 2005-12-27 Stereotaxis, Inc. Electrophysiology catheter
US7280863B2 (en) * 2003-10-20 2007-10-09 Magnetecs, Inc. System and method for radar-assisted catheter guidance and control
US7604658B2 (en) * 2004-05-04 2009-10-20 Codman & Shurtleff, Inc. Multiple lumen sensor attachment
US7516416B2 (en) 2004-06-04 2009-04-07 Stereotaxis, Inc. User interface for remote control of medical devices
FR2872696B1 (en) * 2004-07-07 2007-09-28 Perouse Soc Par Actions Simpli INTRODUCER FOR ENDOLUMINAL INTERVENTION
US20060036163A1 (en) * 2004-07-19 2006-02-16 Viswanathan Raju R Method of, and apparatus for, controlling medical navigation systems
US20080006280A1 (en) * 2004-07-20 2008-01-10 Anthony Aliberto Magnetic navigation maneuvering sheath
US20060144407A1 (en) * 2004-07-20 2006-07-06 Anthony Aliberto Magnetic navigation manipulation apparatus
US20060144408A1 (en) * 2004-07-23 2006-07-06 Ferry Steven J Micro-catheter device and method of using same
US7831294B2 (en) * 2004-10-07 2010-11-09 Stereotaxis, Inc. System and method of surgical imagining with anatomical overlay for navigation of surgical devices
WO2006069257A2 (en) 2004-12-20 2006-06-29 Stereotaxis, Inc. Contact over torque with three dimensional anatomical data
WO2006076394A2 (en) 2005-01-11 2006-07-20 Stereotaxis, Inc. Navigation using sensed physiological data as feedback
US7756308B2 (en) * 2005-02-07 2010-07-13 Stereotaxis, Inc. Registration of three dimensional image data to 2D-image-derived data
US7742803B2 (en) * 2005-05-06 2010-06-22 Stereotaxis, Inc. Voice controlled user interface for remote navigation systems
US20060281990A1 (en) * 2005-05-06 2006-12-14 Viswanathan Raju R User interfaces and navigation methods for vascular navigation
US8027714B2 (en) 2005-05-27 2011-09-27 Magnetecs, Inc. Apparatus and method for shaped magnetic field control for catheter, guidance, control, and imaging
US20070062546A1 (en) * 2005-06-02 2007-03-22 Viswanathan Raju R Electrophysiology catheter and system for gentle and firm wall contact
US20070060992A1 (en) * 2005-06-02 2007-03-15 Carlo Pappone Methods and devices for mapping the ventricle for pacing lead placement and therapy delivery
US9314222B2 (en) 2005-07-07 2016-04-19 Stereotaxis, Inc. Operation of a remote medical navigation system using ultrasound image
US20070038065A1 (en) * 2005-07-07 2007-02-15 Creighton Francis M Iv Operation of a remote medical navigation system using ultrasound image
US20070021744A1 (en) * 2005-07-07 2007-01-25 Creighton Francis M Iv Apparatus and method for performing ablation with imaging feedback
US7603905B2 (en) * 2005-07-08 2009-10-20 Stereotaxis, Inc. Magnetic navigation and imaging system
US7769444B2 (en) 2005-07-11 2010-08-03 Stereotaxis, Inc. Method of treating cardiac arrhythmias
US7690619B2 (en) * 2005-07-12 2010-04-06 Stereotaxis, Inc. Apparatus for pivotally orienting a projection device
US7416335B2 (en) * 2005-07-15 2008-08-26 Sterotaxis, Inc. Magnetically shielded x-ray tube
US8192374B2 (en) * 2005-07-18 2012-06-05 Stereotaxis, Inc. Estimation of contact force by a medical device
US20070043455A1 (en) * 2005-07-26 2007-02-22 Viswanathan Raju R Apparatus and methods for automated sequential movement control for operation of a remote navigation system
US20070040670A1 (en) * 2005-07-26 2007-02-22 Viswanathan Raju R System and network for remote medical procedures
US7818076B2 (en) 2005-07-26 2010-10-19 Stereotaxis, Inc. Method and apparatus for multi-system remote surgical navigation from a single control center
US7495537B2 (en) 2005-08-10 2009-02-24 Stereotaxis, Inc. Method and apparatus for dynamic magnetic field control using multiple magnets
US8784336B2 (en) 2005-08-24 2014-07-22 C. R. Bard, Inc. Stylet apparatuses and methods of manufacture
US20070055124A1 (en) * 2005-09-01 2007-03-08 Viswanathan Raju R Method and system for optimizing left-heart lead placement
US7869854B2 (en) 2006-02-23 2011-01-11 Magnetecs, Inc. Apparatus for magnetically deployable catheter with MOSFET sensor and method for mapping and ablation
US20080015427A1 (en) * 2006-06-30 2008-01-17 Nathan Kastelein System and network for remote medical procedures
US7961924B2 (en) 2006-08-21 2011-06-14 Stereotaxis, Inc. Method of three-dimensional device localization using single-plane imaging
US8242972B2 (en) 2006-09-06 2012-08-14 Stereotaxis, Inc. System state driven display for medical procedures
US7747960B2 (en) 2006-09-06 2010-06-29 Stereotaxis, Inc. Control for, and method of, operating at least two medical systems
US8244824B2 (en) 2006-09-06 2012-08-14 Stereotaxis, Inc. Coordinated control for multiple computer-controlled medical systems
US7567233B2 (en) 2006-09-06 2009-07-28 Stereotaxis, Inc. Global input device for multiple computer-controlled medical systems
US8273081B2 (en) 2006-09-08 2012-09-25 Stereotaxis, Inc. Impedance-based cardiac therapy planning method with a remote surgical navigation system
WO2008033829A2 (en) 2006-09-11 2008-03-20 Stereotaxis, Inc. Automated mapping of anatomical features of heart chambers
US8135185B2 (en) 2006-10-20 2012-03-13 Stereotaxis, Inc. Location and display of occluded portions of vessels on 3-D angiographic images
US7794407B2 (en) 2006-10-23 2010-09-14 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
US8388546B2 (en) 2006-10-23 2013-03-05 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
GB0623395D0 (en) 2006-11-23 2007-01-03 Renishaw Plc Port
US7740647B2 (en) * 2006-12-04 2010-06-22 Implicitcare, Llc Necklift procedure and instruments for performing same
US20080132946A1 (en) * 2006-12-04 2008-06-05 Gregory Paul Mueller Skin port
EP2989975B1 (en) 2007-02-06 2018-06-13 Medtronic MiniMed, Inc. Optical systems and methods for rationmetric measurement of blood glucose concentration
US20080249395A1 (en) * 2007-04-06 2008-10-09 Yehoshua Shachar Method and apparatus for controlling catheter positioning and orientation
JP5517919B2 (en) 2007-05-10 2014-06-11 グルメトリクス、 インク． Balanced non-consumable fluorescent sensor for immediate intravascular glucose measurement
US20080312673A1 (en) * 2007-06-05 2008-12-18 Viswanathan Raju R Method and apparatus for CTO crossing
US8024024B2 (en) 2007-06-27 2011-09-20 Stereotaxis, Inc. Remote control of medical devices using real time location data
WO2009009497A1 (en) 2007-07-06 2009-01-15 Stereotaxis, Inc. Management of live remote medical display
GB0719608D0 (en) * 2007-10-08 2007-11-14 Renishaw Plc Medical Apparatus
US8118784B2 (en) 2007-10-30 2012-02-21 Cook Medical Technologies Llc Haemostatic valve
WO2009061860A1 (en) 2007-11-05 2009-05-14 Stereotaxis, Inc. Magnetically guided energy delivery apparatus
WO2009067626A1 (en) 2007-11-21 2009-05-28 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
US10449330B2 (en) 2007-11-26 2019-10-22 C. R. Bard, Inc. Magnetic element-equipped needle assemblies
US9521961B2 (en) 2007-11-26 2016-12-20 C. R. Bard, Inc. Systems and methods for guiding a medical instrument
CN101925333B (en) 2007-11-26 2014-02-12 C·R·巴德股份有限公司 Integrated system for intravascular placement of catheter
US10524691B2 (en) 2007-11-26 2020-01-07 C. R. Bard, Inc. Needle assembly including an aligned magnetic element
US9649048B2 (en) 2007-11-26 2017-05-16 C. R. Bard, Inc. Systems and methods for breaching a sterile field for intravascular placement of a catheter
US8781555B2 (en) 2007-11-26 2014-07-15 C. R. Bard, Inc. System for placement of a catheter including a signal-generating stylet
US10751509B2 (en) 2007-11-26 2020-08-25 C. R. Bard, Inc. Iconic representations for guidance of an indwelling medical device
US9636031B2 (en) 2007-11-26 2017-05-02 C.R. Bard, Inc. Stylets for use with apparatus for intravascular placement of a catheter
US8849382B2 (en) 2007-11-26 2014-09-30 C. R. Bard, Inc. Apparatus and display methods relating to intravascular placement of a catheter
US8478382B2 (en) 2008-02-11 2013-07-02 C. R. Bard, Inc. Systems and methods for positioning a catheter
WO2009129186A2 (en) 2008-04-17 2009-10-22 Glumetrics, Inc. Sensor for percutaneous intravascular deployment without an indwelling cannula
US8025640B2 (en) 2008-06-27 2011-09-27 Tyco Healthcare Group Lp Pressurized surgical valve
US9901714B2 (en) 2008-08-22 2018-02-27 C. R. Bard, Inc. Catheter assembly including ECG sensor and magnetic assemblies
US8437833B2 (en) 2008-10-07 2013-05-07 Bard Access Systems, Inc. Percutaneous magnetic gastrostomy
US8457714B2 (en) 2008-11-25 2013-06-04 Magnetecs, Inc. System and method for a catheter impedance seeking device
US20120095364A1 (en) * 2009-02-10 2012-04-19 Bobo Sr Donald E Bolt Stop System For Use In Accessing Intracranial Space
US10537713B2 (en) 2009-05-25 2020-01-21 Stereotaxis, Inc. Remote manipulator device
JP5795576B2 (en) 2009-06-12 2015-10-14 バード・アクセス・システムズ，インコーポレーテッド Method of operating a computer-based medical device that uses an electrocardiogram (ECG) signal to position an intravascular device in or near the heart
US9532724B2 (en) 2009-06-12 2017-01-03 Bard Access Systems, Inc. Apparatus and method for catheter navigation using endovascular energy mapping
WO2011019760A2 (en) 2009-08-10 2011-02-17 Romedex International Srl Devices and methods for endovascular electrography
EP2483679A4 (en) 2009-09-30 2013-04-24 Glumetrics Inc Sensors with thromboresistant coating
US10639008B2 (en) 2009-10-08 2020-05-05 C. R. Bard, Inc. Support and cover structures for an ultrasound probe head
US11103213B2 (en) 2009-10-08 2021-08-31 C. R. Bard, Inc. Spacers for use with an ultrasound probe
CN102695542B (en) 2009-11-02 2015-08-12 脉冲治疗公司 For magnetic potential stator system and the method for controlled in wireless magnet rotor
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
US20110112396A1 (en) 2009-11-09 2011-05-12 Magnetecs, Inc. System and method for targeting catheter electrodes
NL2003831C2 (en) * 2009-11-19 2011-05-23 Neurendo B V A shaft connector.
EP2531098B1 (en) 2010-02-02 2020-07-15 C.R. Bard, Inc. Apparatus and method for catheter navigation and tip location
GB201002370D0 (en) * 2010-02-12 2010-03-31 Renishaw Ireland Ltd Percutaneous drug delivery apparatus
WO2011150376A1 (en) 2010-05-28 2011-12-01 C.R. Bard, Inc. Apparatus for use with needle insertion guidance system
MX2012013858A (en) 2010-05-28 2013-04-08 Bard Inc C R Insertion guidance system for needles and medical components.
MX338127B (en) 2010-08-20 2016-04-04 Bard Inc C R Reconfirmation of ecg-assisted catheter tip placement.
CN103189009B (en) 2010-10-29 2016-09-07 C·R·巴德股份有限公司 The bio-impedance auxiliary of Medical Devices is placed
US9440059B2 (en) * 2011-03-18 2016-09-13 Cook Medical Technologies Llc Adjustable diameter hemostatic valve
US9855405B2 (en) * 2011-04-29 2018-01-02 Medtronic, Inc. Burr hole cap assembly with therapy delivery member orientation feature
KR20140051284A (en) 2011-07-06 2014-04-30 씨. 알. 바드, 인크. Needle length determination and calibration for insertion guidance system
US9615759B2 (en) * 2011-07-12 2017-04-11 Bard Access Systems, Inc. Devices and methods for ECG guided vascular access
USD699359S1 (en) 2011-08-09 2014-02-11 C. R. Bard, Inc. Ultrasound probe head
USD724745S1 (en) 2011-08-09 2015-03-17 C. R. Bard, Inc. Cap for an ultrasound probe
WO2013070775A1 (en) 2011-11-07 2013-05-16 C.R. Bard, Inc Ruggedized ultrasound hydrogel insert
US9883878B2 (en) 2012-05-15 2018-02-06 Pulse Therapeutics, Inc. Magnetic-based systems and methods for manipulation of magnetic particles
CN104837413B (en) 2012-06-15 2018-09-11 C·R·巴德股份有限公司 Detect the device and method of removable cap on ultrasonic detector
US20150011868A1 (en) * 2013-06-11 2015-01-08 Adventist Health System/Sunbelt, Inc. MRI-Compatible Fiducial Markers and Methods for Using the Same
ES2811323T3 (en) 2014-02-06 2021-03-11 Bard Inc C R Systems for the guidance and placement of an intravascular device
WO2015143025A1 (en) 2014-03-18 2015-09-24 Monteris Medical Corporation Image-guided therapy of a tissue
US20150265353A1 (en) 2014-03-18 2015-09-24 Monteris Medical Corporation Image-guided therapy of a tissue
US10675113B2 (en) 2014-03-18 2020-06-09 Monteris Medical Corporation Automated therapy of a three-dimensional tissue region
WO2016049155A1 (en) * 2014-09-23 2016-03-31 Wake Forest University Health Sciences Subdural drainage catheter with self contained mechanism for restoration of flow following catheter obstruction
US10973584B2 (en) 2015-01-19 2021-04-13 Bard Access Systems, Inc. Device and method for vascular access
US10327830B2 (en) 2015-04-01 2019-06-25 Monteris Medical Corporation Cryotherapy, thermal therapy, temperature modulation therapy, and probe apparatus therefor
WO2016210325A1 (en) 2015-06-26 2016-12-29 C.R. Bard, Inc. Connector interface for ecg-based catheter positioning system
CN105435358B (en) * 2015-11-25 2018-12-21 菏泽医学专科学校 A kind of implanted intracranial administration intubation suitable for Neuroscience Research
US11000207B2 (en) 2016-01-29 2021-05-11 C. R. Bard, Inc. Multiple coil system for tracking a medical device
US10478265B2 (en) 2017-03-31 2019-11-19 Integra Lifesciences Corporation Cranial fixation device
US11918315B2 (en) 2018-05-03 2024-03-05 Pulse Therapeutics, Inc. Determination of structure and traversal of occlusions using magnetic particles
US10992079B2 (en) 2018-10-16 2021-04-27 Bard Access Systems, Inc. Safety-equipped connection systems and methods thereof for establishing electrical connections

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484420A (en) * 1992-07-09 1996-01-16 Wilson-Cook Medical Inc. Retention bolsters for percutaneous catheters
US5713858A (en) * 1995-04-28 1998-02-03 Medtronic, Inc. Permanently implantable guiding catheter
US5713869A (en) * 1995-03-08 1998-02-03 Morejon; Orlando Trocar assembly
US5728103A (en) * 1996-08-23 1998-03-17 Applied Medical Technology, Inc. Implantable subcutaneous access device and method of using same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3021842A (en) * 1958-11-05 1962-02-20 John F Flood Hypodermic needle guide
US3460537A (en) * 1966-09-26 1969-08-12 Donald C Zeis Stereotactic guide for use in the creation of destructive brain lesions
US4244362A (en) * 1978-11-29 1981-01-13 Anderson Charles C Endotracheal tube control device
US4445501A (en) * 1981-05-07 1984-05-01 Mccormick Laboratories, Inc. Circuits for determining very accurately the position of a device inside biological tissue
US4809694A (en) * 1987-05-19 1989-03-07 Ferrara Vincent L Biopsy guide
US5176697A (en) * 1989-04-06 1993-01-05 Hasson Harrith M Laparoscopic cannula
DE9006056U1 (en) * 1990-05-29 1991-09-26 Kraus, Werner, Dipl.-Ing., 8000 Muenchen, De
US5389080A (en) * 1990-07-26 1995-02-14 Yoon; Inbae Endoscopic portal for use in endoscopic procedures and methods therefor
ATE175852T1 (en) * 1991-11-06 1999-02-15 Inbae Yoon HOLDER FOR SURGICAL INSTRUMENTS
US5211624A (en) * 1991-12-09 1993-05-18 Cinberg James Z Surgical closure device method
CA2093748C (en) * 1992-04-24 1996-11-12 Roy D. Gravener Valve assembly for introducing instruments into body cavities
US5425382A (en) * 1993-09-14 1995-06-20 University Of Washington Apparatus and method for locating a medical tube in the body of a patient
EP0764005A1 (en) * 1994-03-26 1997-03-26 3i Group plc Gas-tight seal for surgical trocars
US5454179A (en) * 1994-05-26 1995-10-03 Bulka; David B. Cassette display frame
US5662600A (en) * 1995-09-29 1997-09-02 Pudenz-Schulte Medical Research Corporation Burr-hole flow control device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484420A (en) * 1992-07-09 1996-01-16 Wilson-Cook Medical Inc. Retention bolsters for percutaneous catheters
US5713869A (en) * 1995-03-08 1998-02-03 Morejon; Orlando Trocar assembly
US5713858A (en) * 1995-04-28 1998-02-03 Medtronic, Inc. Permanently implantable guiding catheter
US5728103A (en) * 1996-08-23 1998-03-17 Applied Medical Technology, Inc. Implantable subcutaneous access device and method of using same

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118548B2 (en) 1996-09-18 2006-10-10 Sinu Shunt A/S Device for the treatment of hydrocephalus
WO2002007811A1 (en) * 2000-07-25 2002-01-31 Csf Dynamics A/S A ventricle drain
US6905474B2 (en) 2000-09-11 2005-06-14 Csf Dynamic A/S Fluid shunt system and a method for the treatment of hydrocephalus
CN100506314C (en) * 2005-07-04 2009-07-01 中国科学院心理研究所 Implanted intracranial administration intubate suitable for neuroscience research
WO2019219784A1 (en) 2018-05-17 2019-11-21 National University Of Ireland, Galway A valved introducer sheath

Also Published As

Publication number Publication date
US6152933A (en) 2000-11-28
AU6325798A (en) 1999-05-31

Similar Documents

Publication Publication Date Title
US6152933A (en) Intracranial bolt and method of placing and using an intracranial bolt to position a medical device
EP1164950B1 (en) A surgical access device
US7214185B1 (en) Surgical access device
US6945932B1 (en) Surgical access device
EP0744978B1 (en) Cerebral dilator
US5857999A (en) Small diameter introducer for laparoscopic instruments
AU696289B2 (en) Apparatus for use in surgery
US9283314B2 (en) Cannula systems
US7593777B2 (en) Fixation of a medical implant to the exterior of a body organ
EP1035804B1 (en) Seal member for surgical trocar
EP0784989B1 (en) Apparatus for performing a tracheostomy
US5437644A (en) Method and apparatus for replacing a cannula
US4263917A (en) Method of sealing bile duct during cholangiography
US20070060884A1 (en) Apparatus for insertion between a medical tube and a body tissue opening
US20080058851A1 (en) Method and apparatus for assisting in the introduction of surgical implements into a body
CN108025161B (en) Dilation delivery system for medical devices
WO2011041578A2 (en) Detachable balloon catheter
US11051845B2 (en) Non-surgical chest tube introducer
JP5172842B2 (en) Inter-organization fixation device and method of use thereof
JP2820571B2 (en) Trocar
US10722107B2 (en) Video-guided chest tube insertion system
JP2511899Y2 (en) Balloon catheter for mounting medical equipment
JPH10108910A (en) Freely removable blood seal
CN114533218A (en) Puncture outfit, inner sleeve device and sealing structure
WO2009136871A1 (en) An improved cannula adaptor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase