WO1999044655A2 - Medication infusion set - Google Patents

Medication infusion set Download PDF

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Publication number
WO1999044655A2
WO1999044655A2 PCT/US1999/004757 US9904757W WO9944655A2 WO 1999044655 A2 WO1999044655 A2 WO 1999044655A2 US 9904757 W US9904757 W US 9904757W WO 9944655 A2 WO9944655 A2 WO 9944655A2
Authority
WO
WIPO (PCT)
Prior art keywords
cannula
needle
infusion
medication
housing
Prior art date
Application number
PCT/US1999/004757
Other languages
French (fr)
Other versions
WO1999044655A3 (en
Inventor
Jeffery V. Funderburk
Nicholas Leif Bowman
Original Assignee
Minimed Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minimed Inc. filed Critical Minimed Inc.
Priority to DE69940222T priority Critical patent/DE69940222D1/en
Priority to DK99912273T priority patent/DK1223997T3/en
Priority to AU30685/99A priority patent/AU3068599A/en
Priority to EP99912273A priority patent/EP1223997B1/en
Priority to US09/623,287 priority patent/US6520938B1/en
Publication of WO1999044655A2 publication Critical patent/WO1999044655A2/en
Publication of WO1999044655A3 publication Critical patent/WO1999044655A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0097Catheters; Hollow probes characterised by the hub
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02Holding devices, e.g. on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06Body-piercing guide needles or the like
    • A61M25/0606"Over-the-needle" catheter assemblies, e.g. I.V. catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1587Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body suitable for being connected to an infusion line after insertion into a patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02Holding devices, e.g. on the body
    • A61M2025/0266Holding devices, e.g. on the body using pads, patches, tapes or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/1011Locking means for securing connection; Additional tamper safeties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/14Tube connectors; Tube couplings for connecting tubes having sealed ends

Definitions

  • This invention relates generally to devices and methods for delivering a selected medication or other therapeutic fluid to a patient at a subcutaneous infusion site. More particularly, this invention relates to an improved medication infusion set of the type having a soft or flexible cannula adapted for subcutaneous placement, in combination with an infusion needle associated with a protective shroud plate to minimize risk of patient contact therewith while providing a high strength and unidirectional releasible coupling with the cannula.
  • the selected medication is then coupled to the cannula, typically by means of a length of infusion tubing connected to a medication source, to deliver the medication through the cannula to the patient.
  • the infusion tubing is connected to the cannula housing at a location downstream from the septum as shown, for example, in U.S. Patents 4,755,173; 5,176,662; and 5,257,980.
  • the infusion tubing is coupled to the cannula housing by means of an infusion needle passed through the septum as shown, for example, in U.S. Patent 5,522,803.
  • Subcutaneous infusion sets of the above-described type are used extensively to administer medication to a patient over an extended period of time.
  • such infusion sets are used with medication infusion pumps of the type described in U.S. Patents 4,562,751 ; 4,685,903; 5,080,653; and 5,097,122 for delivering a long-term medication such as insulin in a continuous or programmable dosage to the patient.
  • medication infusion pumps of the type described in U.S. Patents 4,562,751 ; 4,685,903; 5,080,653; and 5,097,122 for delivering a long-term medication such as insulin in a continuous or programmable dosage to the patient.
  • the medication source must be periodically disconnected from the cannula.
  • the infusion set should be replaced every few days, whereby it is necessary for the patient to uncouple the medication source from an in situ cannula upon removal thereof from the patient, and to recouple the infusion tubing with a second, newly placed cannula.
  • some patients may briefly disconnect the medication source and related infusion tubing from the cannula to facilitate certain activities, such as swimming or bathing, or participation in certain athletic activities, etc.
  • an optimal medication infusion set is adapted for low profile and inobtrusive placement on the patient, while permitting quick and safe periodic disconnection from and reconnection to the medication source.
  • use of an infusion needle adapted for coupling through the self-sealing septum provides a quick and easy structure for connecting and disconnecting the medication source from the cannula, but also subjects the patient to undesirable needle sticks from exposure to the infusion needle.
  • this arrangement requires a strong and reliable mechanical interlock between the cannula housing and the infusion needle to insure consistent and proper interengagement without inadvertent component separation, while permitting quick and easy and repeated disconnection when desired. All of these features are desirably provided in an infusion set constructed from relatively simple and preferably disposable components which can be manufactured in a cost-efficient manner from medical grade plastic or the like.
  • the present invention provides an improved medication infusion set designed to meet these features and advantages, by including an infusion needle associated with a protective shroud plate.
  • the shroud plate closely overlies and substantially encases the infusion needle in a manner minimizing risk of patient contact therewith, while additionally providing a strong guide structure for keyed or one-way interconnection with a cannula housing.
  • an improved medication infusion set for use in delivering medication through a soft cannula to a selected subcutaneous infusion site on a patient.
  • the soft cannula is supported by a compact and low profile cannula housing which includes a self-sealing septum disposed at a proximal or upstream end of the cannula.
  • An infusion hub is provided with latch means for releasible assembly with the cannula housing, and includes a short infusion needle coupled via infusion tubing or the like to a source of the selected medication.
  • the infusion hub includes a protective shroud plate which closely overlies and substantially encases the infusion needle to reduce risk of inadvertent patient contact therewith.
  • the protective shroud plate is configured for unidirectional or one-way reception into a matingly shaped slot formed in the cannula housing upon assembly of the components to provide a high strength connection.
  • the cannula housing comprises a compact plastic molding defining an internal bore for seated reception of a proximal end of the soft cannula.
  • a generally cylindrical needle guide is also seated within the cannula housing and has a downstream end press-fitted into the cannula proximal end.
  • the needle guide defines a flared upstream end, and a ball-shaped resilient and self- sealing septum is retained therein by a retainer clip adapted for snap-fit mounting onto the cannula housing.
  • the cannula housing is initially assembled with an insertion hub which may also be formed from a molded plastic and includes at least one and preferably a pair of resilient latch arms for snap-fit reception into aligned latch ports formed in a proximal face of the cannula housing.
  • the insertion hub carries an elongated insertion needle passed through the septum and needle guide, and further through the soft cannula terminating in a pointed tip end disposed a short distance beyond the distal or downstream end of the cannula.
  • the insertion needle is utilized to pierce the patient's skin at a selected medication infusion site, to transcutaneously place the soft cannula, after which the insertion hub is separated from the cannula housing to withdraw the insertion needle from the cannula.
  • the shroud plate is configured for slide-fit reception into a matingly shaped slot formed in the proximal face of the cannula housing, with a one-way fit, for accurate guided reception of the infusion needle through the septum to extend partially into the needle guide.
  • At least one and preferably a pair of resilient latch arms on the infusion hub are provided for snap-fit reception into the latch ports on the cannula housing to releasibly interlock the components.
  • the infusion hub is securely coupled with the cannula housing with a high strength interconnection resistant to bending or twisting forces that could otherwise contribute to inadvertent component separation.
  • the infusion hub can be quickly and easily disconnected from the cannula housing when desired, for example, when the cannula is replaced or during patient activities requiring temporary disconnection of the medication source.
  • the infusion hub is adapted for quick and easy reconnection to the existing or to a replacement cannula housing, with a simple one-way snap-fit connection, and with the infusion needle substantially concealed from patient contact at all times.
  • FIGURE 1 is an exploded perspective view illustrating a medication infusion set formed in accordance with the novel features of the invention, to include a cannula housing assembled with an insertion hub, shown in exploded relation with a needle guard;
  • FIGURE 5 is an exploded perspective view illustrating assembly of the cannula housing

Abstract

A medication infusion set comprises a housing (14) having a soft cannula (12) protruding therefrom and a self-sealing septum (36) mounted upstream of the cannula. The cannula housing is initially assembled with an insertion hub (16) having an insertion needle (18) extending through the septum and cannula for transcutaneously placing the cannula followed by separation of the insertion hub. An infusion hub (20) is then assembled with the cannula housing and includes a short infusion needle (22) for coupling the cannula with the selected medication supplied via a length of infusion tubing (24). This hub includes a protective shroud plate (26) protruding beyond the tip of the needle to minimize risk of patient contact (28) and slides into a shaped slot (28) formed in the cannula housing to insure a one-way and high strength interconnection between the housing and hub. Releasible latch members interlock the hub with the housing permitting periodic separation when desired.

Description

MEDICATION INFUSION SET
BACKGROUND OF THE INVENTION
This invention relates generally to devices and methods for delivering a selected medication or other therapeutic fluid to a patient at a subcutaneous infusion site. More particularly, this invention relates to an improved medication infusion set of the type having a soft or flexible cannula adapted for subcutaneous placement, in combination with an infusion needle associated with a protective shroud plate to minimize risk of patient contact therewith while providing a high strength and unidirectional releasible coupling with the cannula.
Medication injection or infusion sets are generally well known in the art, to include a relatively soft and flexible cannula providing a transcutaneous pathway through which a selected medication or other therapeutic fluid can be administered to a patient at a selected subcutaneous site. In a common form, the soft cannula is carried by a compact housing to include a resilient self-sealing septum mounted at an upstream end of the cannula. This cannula housing is initially assembled with an insertion needle extending through the septum and cannula, wherein the insertion needle is manipulated to pierce the patient's skin to place the cannula transcutaneously, followed by withdrawal of the insertion needle to leave the soft cannula in place on the patient. The selected medication is then coupled to the cannula, typically by means of a length of infusion tubing connected to a medication source, to deliver the medication through the cannula to the patient. In one configuration, the infusion tubing is connected to the cannula housing at a location downstream from the septum as shown, for example, in U.S. Patents 4,755,173; 5,176,662; and 5,257,980. In another arrangement, the infusion tubing is coupled to the cannula housing by means of an infusion needle passed through the septum as shown, for example, in U.S. Patent 5,522,803.
Subcutaneous infusion sets of the above-described type are used extensively to administer medication to a patient over an extended period of time. For example, such infusion sets are used with medication infusion pumps of the type described in U.S. Patents 4,562,751 ; 4,685,903; 5,080,653; and 5,097,122 for delivering a long-term medication such as insulin in a continuous or programmable dosage to the patient. With such medication delivery systems, however, it is known that the medication source must be periodically disconnected from the cannula. For example, it has been recognized that the infusion set should be replaced every few days, whereby it is necessary for the patient to uncouple the medication source from an in situ cannula upon removal thereof from the patient, and to recouple the infusion tubing with a second, newly placed cannula. In addition, some patients may briefly disconnect the medication source and related infusion tubing from the cannula to facilitate certain activities, such as swimming or bathing, or participation in certain athletic activities, etc.
In this regard, an optimal medication infusion set is adapted for low profile and inobtrusive placement on the patient, while permitting quick and safe periodic disconnection from and reconnection to the medication source. To this end, use of an infusion needle adapted for coupling through the self-sealing septum provides a quick and easy structure for connecting and disconnecting the medication source from the cannula, but also subjects the patient to undesirable needle sticks from exposure to the infusion needle. Moreover, this arrangement requires a strong and reliable mechanical interlock between the cannula housing and the infusion needle to insure consistent and proper interengagement without inadvertent component separation, while permitting quick and easy and repeated disconnection when desired. All of these features are desirably provided in an infusion set constructed from relatively simple and preferably disposable components which can be manufactured in a cost-efficient manner from medical grade plastic or the like.
The present invention provides an improved medication infusion set designed to meet these features and advantages, by including an infusion needle associated with a protective shroud plate. The shroud plate closely overlies and substantially encases the infusion needle in a manner minimizing risk of patient contact therewith, while additionally providing a strong guide structure for keyed or one-way interconnection with a cannula housing.
SUMMARY OF THE INVENTION
In accordance with the invention, an improved medication infusion set is provided for use in delivering medication through a soft cannula to a selected subcutaneous infusion site on a patient. The soft cannula is supported by a compact and low profile cannula housing which includes a self-sealing septum disposed at a proximal or upstream end of the cannula. An infusion hub is provided with latch means for releasible assembly with the cannula housing, and includes a short infusion needle coupled via infusion tubing or the like to a source of the selected medication. The infusion hub includes a protective shroud plate which closely overlies and substantially encases the infusion needle to reduce risk of inadvertent patient contact therewith. The protective shroud plate is configured for unidirectional or one-way reception into a matingly shaped slot formed in the cannula housing upon assembly of the components to provide a high strength connection.
In the preferred form on the invention, the cannula housing comprises a compact plastic molding defining an internal bore for seated reception of a proximal end of the soft cannula. A generally cylindrical needle guide is also seated within the cannula housing and has a downstream end press-fitted into the cannula proximal end. The needle guide defines a flared upstream end, and a ball-shaped resilient and self- sealing septum is retained therein by a retainer clip adapted for snap-fit mounting onto the cannula housing.
The cannula housing is initially assembled with an insertion hub which may also be formed from a molded plastic and includes at least one and preferably a pair of resilient latch arms for snap-fit reception into aligned latch ports formed in a proximal face of the cannula housing. The insertion hub carries an elongated insertion needle passed through the septum and needle guide, and further through the soft cannula terminating in a pointed tip end disposed a short distance beyond the distal or downstream end of the cannula. The insertion needle is utilized to pierce the patient's skin at a selected medication infusion site, to transcutaneously place the soft cannula, after which the insertion hub is separated from the cannula housing to withdraw the insertion needle from the cannula.
The infusion hub also comprises a low profile component of molded plastic or the like and carries the infusion needle in flow communication with the source of the selected medication, typically via a length of infusion tubing. The infusion needle protrudes from a distal face of the infusion hub in close association with the protective shroud plate which protrudes at least slightly beyond the tip end of the infusion needle. In a preferred form, the shroud plate comprises a multifaceted and preferably three-sided structure enclosing the infusion needle on three sides to substantially prevent patient contact and accidental needle sticks. The shroud plate is configured for slide-fit reception into a matingly shaped slot formed in the proximal face of the cannula housing, with a one-way fit, for accurate guided reception of the infusion needle through the septum to extend partially into the needle guide. At least one and preferably a pair of resilient latch arms on the infusion hub are provided for snap-fit reception into the latch ports on the cannula housing to releasibly interlock the components.
In use, the infusion hub is securely coupled with the cannula housing with a high strength interconnection resistant to bending or twisting forces that could otherwise contribute to inadvertent component separation. However, the infusion hub can be quickly and easily disconnected from the cannula housing when desired, for example, when the cannula is replaced or during patient activities requiring temporary disconnection of the medication source. The infusion hub is adapted for quick and easy reconnection to the existing or to a replacement cannula housing, with a simple one-way snap-fit connection, and with the infusion needle substantially concealed from patient contact at all times.
Other features and advantages of the present invention will become more apparent from the following detailed description, taken in conjunction with the accompanying drawings which illustrate, by way of example, the principles of the invention.
BRIEF DESCRIPTION OF THE DRAWINGS
The accompanying drawings illustrate the invention. In such drawings:
FIGURE 1 is an exploded perspective view illustrating a medication infusion set formed in accordance with the novel features of the invention, to include a cannula housing assembled with an insertion hub, shown in exploded relation with a needle guard;
FIGURE 2 is a top plan view showing the cannula housing and insertion hub in exploded relation;
FIGURE 3 is a horizontal sectional view of the insertion hub;
FIGURE 4 is a horizontal sectional view of the cannula housing;
FIGURE 5 is an exploded perspective view illustrating assembly of the cannula housing;
FIGURE 6 is a horizontal sectional view showing the cannula housing and insertion hub in assembled relation;
FIGURE 7 is a top plan view showing the cannula housing and an infusion hub in exploded relation;
FIGURE 8 is a perspective view of the infusion hub shown in FIG. 7, depicting the distal or downstream face thereof;
FIGURE 9 is a horizontal sectional view of the infusion hub;
FIGURE 10 is a horizontal sectional view showing the cannula housing and infusion hub in assembled relation;
FIGURE 11 is a fragmented sectional view illustrating use of the insertion hub for placing the cannula housing on a patient; and
FIGURE 12 is a fragmented sectional view similar to FIG. 11 , and depicting the cannula housing seated on the patient.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
As shown in the exemplary drawings, an improved infusion set is provided for use in administering a selected medication to a patient at a selected subcutaneous infusion site. The infusion set comprises a soft and flexible cannula 12 carried by a compact and low profile cannula housing 14. An inserter hub 16 including an insertion needle 18 is initially assembled with the cannula housing 14 for transcutaneously placing the cannula, as viewed in FIGURES 1-6 and 11. Thereafter, an infusion hub 20 including an infusion needle 22 coupled to a source of a selected medication via a length of infusion tubing 24 is assembled with the cannula housing 14 for delivering the medication to the patient, as viewed in FIGS. 7-10. The infusion hub 20 includes a protective shroud plate 26 closely overlying the infusion needle 22 to prevent undesirable needle sticks, wherein the shroud plate 26 slide-fits into a mating slot 28 formed in the cannula housing 14 to provide a one-way and high strength interconnection of the components.
The medication infusion set of the present invention is particularly suited for delivering medication to a patient on a continuous or programmable basis over an extended period of time, such as, for example, the administration of insulin to a diabetic patient by means of a programmable infusion pump of the type described in U.S. Patents 4,562,751 ; 4,685,903; 5,080,653; and 5,097,122. The infusion set comprises a compact, low profile and economical assembly of components adapted for quick and easy transcutaneous placement of the soft cannula 12 at the selected infusion site, followed by quick and easy coupling of the cannula with the selected medication source. The infusion hub 20 and the cannula housing 14 are constructed for facilitated and repeated interconnection with a unidirectional or one-way fit while minimizing risk of patient contact with the infusion needle 18, and further to provide a high strength attachment which is resistant to inadvertent separation in response to bending, twisting, and tension forces. In addition, the infusion hub 20 and associated infusion needle 18 can be disconnected quickly and easily from the cannula housing 14 by the patient as may be required or desired, for example, when replacing the cannula typically at intervals of several days, or when the patient participates in athletic or other activities such as swimming or bathing wherein temporary disconnection of the infusion pump is warranted. Importantly, the infusion hub 20 can be reconnected rapidly and safely by the patient to the existing or to a replacement cannula housing to provide a strong and reliable component interface.
The cannula housing 14 is shown in detail in FIGS. 4-6, to comprise a compact and low profile component constructed from a medical grade molded plastic which is clear or transparent to facilitate viewing of the infusion site. The cannula housing defines a bore 30 extending therethrough and adapted to receive and support an upstream or proximal end of the soft cannula 12, with a distal end of the cannula protruding outwardly from a smoothly rounded distal face 32 of the cannula housing. In the preferred form, the proximal end of the cannula 12 is press-fit mounted onto a downstream end of a needle guide 34 formed from stainless steel or the like, and these assembled components are compression fitted into the bore 30. In this regard, for facilitated assembly, the bore 30 may be formed in the plastic molded cannula housing 14 in the form of a downwardly open channel.
The upstream end of the needle guide 34 is flared outwardly to form a radially enlarged and generally conical seat for receiving and supporting a resilient self-sealing septum 36 in the form of a ball. The septum 36 is securely retained within the flared end of the needle guide 34 by a small generally U-shaped retainer clip 38. This retainer clip 38 is sized and shaped to fit into an open cavity 40 formed in a proximal face 42 of the cannula housing 14, with a centrally located needle port 44 formed in the clip 38 to permit needle access via the septum 36 and needle guide 34 with the cannula 12, as will be described in more detail. The opposing legs of the U-shaped retainer clip 38 include in-turned latch feet 46 for snap-fit engagement into latch detents 48 formed by the cannula housing 14 on opposite sides of the bore 30, to lock the retainer clip 38 onto the cannula housing. The ball-shaped septum conveniently mounts within the flared end of the needle guide in a self-centered manner, and without reference to orientation, to provide a maximized septum surface area and internal volume within a minimum space.
The cannula housing 14 and related cannula 12, as described above, are shown in FIGS. 1 and 6 in preassembled relation with the insertion hub 16 for use in transcutaneously placing the cannula 12 on the patient at the selected subcutaneous infusion site. To this end, the insertion hub 16 also comprises a compact and low profile component which is preferably formed from molded plastic with an overall size and shape generally conforming with the cannula housing 14. As shown best in FIGS. 2 and 3, the insertion hub 16 rigidly supports a rear or proximal end of the insertion needle 18 which protrudes from the hub 16 and terminates in a pointed distal end tip 50. The insertion needle 18 is adapted to pierce the ball-shaped septum 36 and to extend through the needle guide 34 and further through the soft cannula 12, to position the sharp tip 50 at least slightly beyond the distal end tip of the cannula. In this orientation, a distal face 52 of the insertion hub 16 is substantially butted against the proximal face 42 of the cannula housing 14 (FIGS. 1 and 6). A pair of resilient latch arms 54 on the insertion hub 16 having out-turned latch fingers 56 thereon are received into a corresponding pair of open latch ports 58 formed in the proximal face 42 of the cannula housing, and these latch fingers 56 snap-fit engage with undercut recesses 60 on the cannula housing to retain the insertion hub 16 and the cannula housing 14 in assembled relation.
A shell-shaped needle guard 62 as shown in FIG. 1 is normally provided for mounting onto the preassembled insertion hub 16 and cannula housing 14, to protect against undesired contact with the insertion needle 18. The needle guard 62 may also comprise a simple plastic molding having a size and shape to fit over the protruding insertion needle 16 and the soft cannula 12 thereon, and to include a rearwardly extending clip segment 64 having a latch tooth 66 for releasible reception into an upwardly open notch 68 formed in an upper surface of the insertion hub 16.
When placement of the cannula 12 on the patient is desired, the needle guard 62 is removed from the preassembled insertion hub and cannula housing to expose the insertion needle 18, as viewed in FIG. 1. The preassembled components are then manipulated as a unit, primarily by grasping the insertion hub 16, to pierce the patient's skin 70 at a selected infusion site as shown in FIG. 11. In this regard, in a preferred placement procedure, the infusion site is prepared by initial cleansing followed by placement of a mounting substrate in the form of a patch 72 mounted onto the skin 70 by means of a suitable hypoallergenic or non- irritating adhesive, such as a patch marketed by Wound Management Division of Smith + Nephew of Largo, Florida under the product designation OpSite IV 3000. The patch 72 provides a smoother and flatter mounting base of improved lateral stability for more secure mounting of the cannula housing 14, as compared to direct placement onto the patient's skin 70, and has an attachment surface area significantly greater than the underside surface area of the cannula housing. The insertion needle 18 can be inserted transcutaneously by placement directly through the patch 72, typically at an angle to the skin 70 of about 30 - 45 degrees, to transcutaneously place the cannula 12, with the patch 72 supporting the skin in the region of the needle pierce point. When the cannula is properly placed, the insertion hub 16 can be separated from the cannula housing 14 by squeezing inwardly on the latch arms 54 to permit withdrawal of the insertion needle thereby leaving the cannula 12 in position on the patient. The cannula housing 14 is then secured to the patient by removing a peel- off paper strip 74 from the underside thereof to expose an adhesive layer 76 suited for secure attachment to the patch 72, as viewed in FIG. 12.
In the preferred form, the adhesive layer 76 securing the cannula housing 14 to the patch 72 is chosen for a strong and stable attachment, with the broader and larger surface area of the patch in turn providing a secure and stable mounting relative to the patient's skin 70. As a result, the attachment force retaining the cannula housing 14 to the patch 72, as well as the attachment force retaining the patch 72 to the patient's skin, can significantly exceed the attachment force otherwise achievable by adhering the cannula housing 14 directly to the patient's skin. Accordingly, the cannula housing and the associated cannula 12 are anchored in a manner such that partial pull-out of the cannula is unlikely to occur during normal patient movement and/or inadvertent tugging or pulling of the infusion set. When removal of the cannula is desired, the patch 72 and cannula housing 14 are removed as a unit for disposal. Alternately, it will be understood that the cannula housing 14 may be adhered directly to the patient's skin 70, in the event that the patch 72 is not used.
Following placement of the cannula 12 on the patient, the infusion hub 20 is coupled quickly and easily with the cannula housing 14 for supplying the selected medication to the patient. More particularly, as shown in FIGS. 7-10, the infusion hub 20 also comprises a compact and low profile component of medical grade molded plastic with an overall size and shape for connection to the cannula housing. The infusion hub 20 defines an internal bore 78 for seated reception of the infusion needle 22. A rear end of the infusion needle is positioned for press-fit connection to the length of infusion tubing 24 which, as previously described, is coupled in turn to the appropriate medication source such as a medication infusion pump (not shown). A forward or tip end of the infusion needle 22 protrudes outwardly from a distal face 80 of the infusion hub 20, with a length sufficient to extend through the resilient septum 36 and partially into the metal needle guide 34 within the cannula housing 14, when the infusion hub is connected to the cannula housing. Accordingly, with this geometry, the infusion needle 22 does not protrude beyond the needle guide 34 into the soft cannula 12, thereby minimizing or eliminating risk of needle- caused damage to the soft cannula. A pair of resilient latch arms 82 also project from the distal face 80 of the infusion hub 20 and include out-turned latch fingers 84 for snap-fit engagement into the latch recesses 60 formed in the cannula housing 14 to releasibly lock the components together, with the infusion needle 22 coupling the infusion tubing 24 with the cannula 12.
In accordance with one primary aspect of the invention, the shroud plate 26 extends from the distal face of the infusion hub 20 to closely overlie and protect the infusion needle. As shown, the shroud plate 26 comprises a multifaceted and preferably three-sided structure extending over the top and both sides of the infusion needle 22, and projecting from the infusion hub at least slightly beyond the distal end tip of the infusion needle. With this construction, the shroud plate substantially and effectively shields the infusion needle 22 against significant risk of patient contact therewith during manipulation of the infusion hub to connect or disconnect the infusion tubing from the cannula, thereby substantially preventing undesirable needle sticks.
Moreover, the protective shroud plate 26 presents a keyed structure for unidirectional or one-way connection of the infusion hub 20 with the cannula housing 14, in a manner providing a strong interconnection with accurate guided coupling of the infusion needle 22 through the septum 36 and into the needle guide 34, yet additionally permitting quick and easy disconnection when desired. Specifically, the shroud plate 26 is sized and shaped for slide-fit reception into the matingly shaped and thus preferably three-sided slot 28 formed in the proximal face 42 of the cannula housing 14, to extend over the top and at both sides of the retainer clip 38. The shroud plate 26 slidably fits into the slot 28 in one orientation only, thereby properly positioning and aligning the infusion needle 22 with the retainer clip port 44. As the shroud plate 26 is advanced into the mating slot 28, the needle 22 correspondingly advances through the septum and partially into the needle guide 34, while the latch arms 82 advance into the latch ports 58 for snap-fit connection of the infusion hub 20 to the cannula housing 14. When fully connected, the shroud plate 26 presents a broad and multifaceted surface area engaging the cannula housing within the slot 28 to provide a strong interconnection which is highly resistant to bending, twisting and other forces otherwise contributing to potential inadvertent separation of the components.
However, when disconnection of the components is desired, the latch arms 82 are quickly and easily pressed inwardly to release from the associated latch recesses 60, to permit simple slide-apart separation of the infusion hub 20 from the cannula housing 14. The shroud plate 26 presents a central housing structure between the latch arms 82 to block excess displacement when the latch arms are pressed inwardly, thereby protecting the latch arms against permanent deformation and/or breakage, and correspondingly permitting repeated connection and disconnection of the infusion hub. Importantly, upon such separation, the septum 36 seals the upstream end of the cannula to maintain sterility. During this separated condition, the patient may participate in a variety of activities such as athletic events, swimming or bathing, wherein it may be desirable to avoid exposure of the medication source such as an infusion pump to physical jarring or to water, etc. Alternately, with the infusion hub 20 separated from the cannula housing 14, other medications can be administered to the patient by means of a syringe or the like piercing the septum 36. Still further, separation of the infusion hub 20 from the cannula housing 14 is typically desired at intervals of a few days to permit removal of an in situ cannula and replacement with a new one. In all cases, the infusion hub 20 is quickly and easily reconnected to the associated cannula housing 14 with a simple sliding and snap-fit one-way attachment.
A variety of further modifications and improvements in and to the improved medication infusion set of the present invention will be apparent to persons skilled in the art. Accordingly, no limitation on the invention is intended by way of the foregoing description and accompanying drawings, except at set forth in the appended claims.

Claims

WHAT IS CLAIMED IS:
1. A medication infusion set for transcutaneous delivery of a selected medication to a patient, said infusion set comprising: a cannula housing having a soft cannula mounted thereon with a distal end of said cannula protruding from said cannula housing, and a resilient self-sealing septum mounted on said cannula housing generally at a proximal end of said cannula for normally closing said cannula proximal end; and an infusion hub having an infusion needle mounted thereon with a distal end of said infusion needle protruding from said infusion hub and being adapted for connection to a source of the selected medication, said infusion needle being adapted for insertion through said septum for coupling with said cannula; said infusion hub further including a protective shroud plate protruding therefrom in overlying relation with said infusion needle, said shroud plate being slidably insertable into a generally matingly shaped slot formed in said cannula housing for guided reception of said infusion needle through said septum; said cannula housing and said infusion hub further including releasibly interengageable latch members for releasibly connecting said infusion hub to said cannula housing with said infusion needle inserted through said septum.
2. The medication infusion set of claim 1 wherein said cannula proximal end is press-fit mounted into an open-sided channel formed in said cannula housing.
3. The medication infusion set of claim 1 further including a rigid tubular needle guide interposed between said septum and said cannula proximal end.
4. The medication infusion set of claim 3 wherein said infusion needle has a length to extend through said septum and partially into said needle guide when said cannula housing and infusion hub are connected together.
5. The medication infusion set of claim 3 wherein said needle guide has a downstream end press-fit into said cannula proximal end.
6. The medication infusion set of claim 5 wherein said needle guide and said cannula proximal end are press-fit mounted into an open- sided channel formed in said cannula housing.
7. The medication infusion set of claim 3 wherein said needle guide comprises a metal needle guide.
8. The medication infusion set of claim 1 further including a rigid tubular needle guide interposed between said septum and said cannula proximal end, said needle guide having a downstream end press-fit connected to said cannula proximal end, and an upstream end flared outwardly to form a generally conical seat for receiving and supporting said septum, and further including retainer means mounted on said cannula housing for retaining said septum within said conical seat.
9. The medication infusion set of claim 8 wherein said retainer means comprises a retainer clip for snap-fit mounting onto said cannula housing, said retainer clip having a needle port formed therein.
10. The medication infusion set of claim 8 wherein said septum comprises a resilient self-sealing ball.
11. The medication infusion set of claim 1 further including infusion tubing coupled to said infusion hub for coupling said infusion needle to the medication source.
12. The medication infusion set of claim 1 wherein said shroud plate comprises a plurality of generally planar facets, said slot formed in said cannula housing being generally matingly shaped for one-way reception of said shroud plate.
13. The medication infusion set of claim 12 wherein said shroud plate extends over the top and at opposite sides of said infusion needle.
14. The medication infusion set of claim 12 wherein said shroud plate extends from said infusion hub at least slightly beyond a distal end of said infusion needle.
15. The medication infusion set of claim 1 wherein said latch members comprise at least one resilient latch arm protruding from said infusion hub and at least one latch port having a latch detent therein formed on said cannula housing for snap-fit and releasible engagement with said latch arm.
16. The medication infusion set of claim 1 wherein said latch members comprises a pair of resilient latch arms protruding from said infusion hub at opposite sides of said shroud plate, and a corresponding pair of latch ports each having a latch detent therein formed on said cannula housing for snap-fit and releasible engagement with said latch arms.
17. The medication infusion set of claim 1 further including an insertion hub having an insertion needle mounted thereon with a distal end protruding therefrom, said insertion needle being insertable through said septum to extend through said cannula and terminating with a sharp distal end tip disposed at least slightly beyond a distal end of said cannula, said insertion hub being adapted for transcutaneously placing said cannula on a patient and thereafter being withdrawable from said cannula and cannula housing.
18. The medication infusion set of claim 17 wherein said latch members comprise at least one resilient latch arm protruding from said insertion hub and at least one latch port having a latch detent therein formed on said cannula housing for snap-fit and releasible engagement with said latch arm.
19. The medication infusion set of claim 17 wherein said latch members comprise a pair of resilient latch arms protruding from said insertion hub at opposite sides of said insertion needle, and a corresponding pair of latch ports each having a latch detent therein formed on said cannula housing for snap-fit and releasible engagement with said latch arms.
20. The medication infusion set of claim 17 further including a needle guard for removable mounting onto said insertion hub when said insertion hub is assembled with said cannula housing to encase said insertion needle and said cannula protruding from said cannula housing.
21. The medication infusion set of claim 1 further including an adhesive layer on an underside surface of said cannula housing.
22. The medication infusion set of claim 21 further including an adhesive patch for removable mounting onto the skin of a patient at a selected infusion site, said insertion needle being adapted to pierce said patch and the patient's skin to transcutaneously place said cannula, said adhesive layer being adapted to attach said cannula housing to said patch with an adhesion force greater than the force of attachment of said patch to the patient's skin.
23. The medication infusion set of claim 17 wherein said cannula housing has an underside surface with an adhesive layer thereon, and further including an adhesive patch for placement onto a patient, said insertion needle being adapted for transcutaneously placing said cannula by piercing said patch, said adhesive layer on said cannula housing securing said cannula housing to said patch.
24. The medication infusion set of claim 23 wherein said adhesive patch has an area of attachment to the patient's skin substantially greater than the area of said underside surface on said cannula housing.
25. A medication infusion set for transcutaneous delivery of a selected medication to a patient, said infusion set comprising: a cannula housing having a soft cannula mounted thereon with a distal end of said cannula protruding from said cannula housing, and a resilient self-sealing septum mounted on said cannula housing generally at a proximal end of said cannula for normally closing said cannula proximal end; and an infusion hub having an infusion needle mounted thereon with a distal end of said infusion needle protruding from said infusion hub and being adapted for connection to a source of the selected medication, said infusion needle being adapted for insertion through said septum for coupling with said cannula; said infusion hub further including a protective shroud plate of multifaceted configuration protruding therefrom in overlying relation with said infusion needle and projecting from said infusion hub at least slightly beyond a distal tip end of said infusion needle, said shroud plate being slidably insertable into a generally matingly shaped slot formed in said cannula housing for one-way guided reception of said infusion needle through said septum; said cannula housing and said infusion hub further including releasibly interengageable latch members for releasibly connecting said infusion hub to said cannula housing with said infusion needle inserted through said septum.
26. The medication infusion set of claim 25 wherein said shroud plate has a three-sided construction.
27. The medication infusion set of claim 25 wherein said latch members comprise a pair of resilient latch arms protruding from said infusion hub at opposite sides of said shroud plate, and a corresponding pair of latch ports each having a latch detent therein formed on said cannula housing for snap-fit and releasible engagement with said latch arms.
28. The medication infusion set of claim 25 further including an insertion hub having an insertion needle mounted thereon with a distal end protruding therefrom, said insertion needle being insertable through said septum to extend through said cannula and terminating with a sharp distal end tip disposed at least slightly beyond a distal end of said cannula, said insertion hub being adapted for transcutaneously placing said cannula on a patient and thereafter being withdrawable from said cannula and cannula housing.
29. A medication infusion set for transcutaneous delivery of a selected medication to a patient, said infusion set comprising: a cannula housing; a soft cannula; a rigid tubular needle guide having a downstream end press-fit mounted with a proximal end of said soft cannula, said needle guide and said cannula proximal end being carried within a bore formed in said cannula housing with a distal end of said cannula protruding from said cannula housing, said needle guide having an upstream end flared outwardly in a generally conical configuration; a resilient self-sealing septum; and retainer means for retaining said septum seated within said flared upstream of said needle guide.
30. The medication infusion set of claim 29 wherein said needle guide downstream end is press-fitted into said cannula proximal end.
31. The medication infusion set of claim 29 wherein said needle guide and said cannula proximal end are press-fit mounted into an open- sided channel formed in said cannula housing.
32. The medication infusion set of claim 30 wherein said channel is formed in an underside surface of said cannula housing, and further including an adhesive layer covering said underside surface.
33. The medication infusion set of claim 29 wherein said needle guide comprises a metal needle guide.
34. The medication infusion set of claim 29 wherein said septum comprises a self-sealing ball.
35. The medication infusion set of clam 29 wherein said retainer means comprises a retainer clip for snap-fit mounting onto said cannula, said retainer clip having a needle port formed therein.
36. The medication infusion set of claim 29 wherein said infusion needle has a length to extend through said septum and partially into said needle guide and defining a distal end tip terminating short of said cannula.
37. A medication infusion set for transcutaneous delivery of a selected medication to a patient, said infusion set comprising: a cannula housing having a soft cannula mounted thereon with a distal end of said cannula protruding from said cannula housing; insertion means including an insertion needle extending through said cannula housing and through said cannula, said insertion needle having a sharp tip end disposed at least slightly beyond a distal end tip of said cannula; and an adhesive patch for removable mounting onto a patient's skin at a selected infusion site, said adhesive patch including adhesive means for attachment to the patient's skin; said insertion means being adapted to manipulate said insertion needle for piercing said patch and the patient's skin to transcutaneously place said cannula and for thereafter removing said insertion needle from said cannula and said cannula housing to leave said cannula on the patient, said adhesive layer on said cannula housing connecting said cannula housing to said patch with an attachment force greater than the force of attachment of said patch to the patient's skin.
38. The medication infusion set of claim 37 wherein said cannula housing defines an underside surface with an adhesive layer thereon for adhesive attachment to said patch.
39. The medication infusion set of claim 38 wherein the area of attachment of said patch to the patient's skin is substantially greater than the area of said underside surface of said cannula housing.
40. A method of transcutaneously placing and securing a medical device on a patient, said method comprising the steps of: mounting the medical device on an insertion needle; securing an adhesive patch onto a patient's skin at a selected site for placement of the medical device; transcutaneously placing the medical device at said selected site by manipulating the insertion needle to pierce the patch and the patient's skin to carry the medical device to a transcutaneous position; and withdrawing the insertion needle from the medical device and the patient while leaving the medical device in said transcutaneous position.
41. The method of claim 40 wherein the medical device is carried by a housing member, and further including the step of adhesively securing the housing member to the patch.
42. The method of claim 41 wherein said housing member has an underside surface with an adhesive layer thereon, and a peel-off strip overlying said adhesive layer, and further wherein said step of adhesively securing said housing member to the patch comprising removing said peel- off strip subsequent to transcutaneously placing the medical device and pressing said housing member against said patch.
43. The method of claim 42 wherein the area of attachment of the patch to the patient's skin is substantially greater than the area of said underside surface of said housing member.
PCT/US1999/004757 1998-03-04 1999-03-03 Medication infusion set WO1999044655A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE69940222T DE69940222D1 (en) 1998-03-04 1999-03-03 MEDICAL INFUSION DEVICE
DK99912273T DK1223997T3 (en) 1998-03-04 1999-03-03 Medical infusion set
AU30685/99A AU3068599A (en) 1998-03-04 1999-03-03 Medication infusion set
EP99912273A EP1223997B1 (en) 1998-03-04 1999-03-03 Medication infusion set
US09/623,287 US6520938B1 (en) 1998-03-04 1999-03-03 Medication infusion set

Applications Claiming Priority (2)

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US09/034,626 1998-03-04
US09/034,626 US6056718A (en) 1998-03-04 1998-03-04 Medication infusion set

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WO1999044655A2 true WO1999044655A2 (en) 1999-09-10
WO1999044655A3 WO1999044655A3 (en) 1999-10-28

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EP (1) EP1223997B1 (en)
AU (1) AU3068599A (en)
DE (1) DE69940222D1 (en)
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WO (1) WO1999044655A2 (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001052617A2 (en) * 2000-01-18 2001-07-26 Sterling Medivations, Inc. Subcutaneous injection set for use with a reservoir that has a septum
WO2002094352A2 (en) * 2001-05-18 2002-11-28 Deka Products Limited Partnership Infusion set for a fluid pump
EP1368080A2 (en) * 2001-03-04 2003-12-10 Sterling Medivations, Inc. Infusion hub assembly and fluid line disconnect system
EP1839699A1 (en) * 2004-12-22 2007-10-03 Terumo Kabushiki Kaisha Connector, tube assembly, infusion tube set, and container for medical use
US7306578B2 (en) 2002-01-04 2007-12-11 Deka Products Limited Partnership Loading mechanism for infusion pump
GB2450781A (en) * 2007-07-06 2009-01-07 Applied Medical Technology Ltd Connector with shielded needle for connecting a tube to an infusion device
US7517335B2 (en) 2002-02-18 2009-04-14 Cequr Aps Device for administering of medication in fluid form
WO2011112331A1 (en) * 2010-03-10 2011-09-15 Becton, Dickinson And Company Catheter device with hooding feature
US9180245B2 (en) 2008-10-10 2015-11-10 Deka Products Limited Partnership System and method for administering an infusible fluid
WO2017211493A1 (en) * 2016-06-10 2017-12-14 Fresenius Kabi Deutschland Gmbh Cannulation device
WO2018186964A3 (en) * 2017-04-07 2019-01-17 Becton, Dickinson And Company Low-profile extension for a catheter assembly
EP4137175A1 (en) * 2021-08-18 2023-02-22 Medtronic MiniMed, Inc. Infusion set with rotatable hub and process

Families Citing this family (307)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1044028B2 (en) 1997-12-31 2010-01-20 Medtronic MiniMed, Inc. Insertion device for an insertion set
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949084B2 (en) * 1998-05-14 2005-09-27 Disetronic Licensing Ag Catheter head for subcutaneous administration of an active substance
US6355021B1 (en) * 1998-07-14 2002-03-12 Maersk Medical A/S Medical puncturing device
US6391007B2 (en) 1998-12-23 2002-05-21 Joseph Jawshin Chang Solid blunt for a needle assembly
US20020120231A1 (en) * 2000-01-18 2002-08-29 Douglas Joel S. Subcutaneous injection set with secondary injection septum
US6572586B1 (en) * 2000-07-25 2003-06-03 Animas Corporation Low profile infusion set
CA2426157A1 (en) * 2000-10-17 2002-04-25 Patricia G. Schneider Emergency medical dispensing card
US6673440B2 (en) 2000-11-06 2004-01-06 Sterling Medivations, Inc. Subcutaneous injection set tubing with solvent bonding
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US8343115B2 (en) * 2001-01-05 2013-01-01 Applied Diabetes Research, Inc. Low profile pivoting joint infusion assembly
US6579267B2 (en) * 2001-01-05 2003-06-17 Applied Diabetes Research, Inc. Pivoting joint infusion assembly
US7083597B2 (en) * 2001-01-05 2006-08-01 Applied Diabetes Research, Inc. Pivoting joint infusion system with seal
DE20103979U1 (en) * 2001-03-08 2001-06-21 Caremed Medical Produkte Ag Port for an implantable port system
EP1397068A2 (en) 2001-04-02 2004-03-17 Therasense, Inc. Blood glucose tracking apparatus and methods
US20020161332A1 (en) * 2001-04-13 2002-10-31 Kirk Ramey Infusion set with tape
ES2230200T3 (en) * 2001-05-09 2005-05-01 Unomedical A/S DEVICE FOR THE ADMINISTRATION OF A THERAPEUTIC AGENT.
US8034026B2 (en) 2001-05-18 2011-10-11 Deka Products Limited Partnership Infusion pump assembly
JP2005500319A (en) * 2001-06-27 2005-01-06 イーラン ファーマスーティカルズ、インコーポレイテッド Β-hydroxyamine derivatives useful for the treatment of Alzheimer's disease
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US6981965B2 (en) 2001-10-31 2006-01-03 Luther Research Partners Llc Universal passive protector for an IV catheter
ITTO20011228A1 (en) * 2001-12-28 2003-06-28 Cane Srl DISPOSABLE NEEDLE CONTAINER.
DE60304681T2 (en) * 2002-02-12 2007-01-25 Unomedical A/S INFUSION DEVICE WITH NADELSCHUTZHÜLSE
EP1490133B1 (en) * 2002-03-08 2015-04-22 Applied Diabetes Research, Inc. Low profile, pivotal connection infusion assembly
US20030195609A1 (en) * 2002-04-10 2003-10-16 Scimed Life Systems, Inc. Hybrid stent
US7338465B2 (en) * 2002-07-02 2008-03-04 Patton Medical Devices, Lp Infusion device and method thereof
US20040068230A1 (en) 2002-07-24 2004-04-08 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US7527608B2 (en) * 2002-08-12 2009-05-05 Lma North America, Inc. Medication infusion and aspiration system and method
US20040051019A1 (en) * 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
US7594909B2 (en) * 2002-09-02 2009-09-29 Unomedical, A/S Apparatus and method for adjustment of the length of an infusion tubing
AU2003258486A1 (en) * 2002-09-02 2004-03-19 Unomedical A/S A device for subcutaneous administration of a medicament to a patient and tubing for same
AU2003258487A1 (en) * 2002-09-02 2004-03-19 Unomedical A/S A device for subcutaneous administration of a medicament to a patient
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
DK200201823A (en) 2002-11-26 2004-05-27 Maersk Medical As Connection piece for a hose connection
DE10255817A1 (en) * 2002-11-29 2004-06-17 Disetronic Licensing Ag Catheter head with lockable sealing element
US7125396B2 (en) * 2002-12-30 2006-10-24 Cardinal Health 303, Inc. Safety catheter system and method
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US20040143218A1 (en) * 2003-01-21 2004-07-22 Animas Corporation Needle having optimum grind for reduced insertion force
US20040158202A1 (en) * 2003-02-12 2004-08-12 Soren Jensen Cover
US6923791B2 (en) * 2003-03-31 2005-08-02 Sterling Medivations, Inc. Infusion device having offset flow path
US7070580B2 (en) * 2003-04-01 2006-07-04 Unomedical A/S Infusion device and an adhesive sheet material and a release liner
JP2004305466A (en) * 2003-04-08 2004-11-04 Nipro Corp Medical connector set and catheter set for dwelling using the same
JP3864925B2 (en) * 2003-04-08 2007-01-10 ニプロ株式会社 Indwelling catheter set
US20040204692A1 (en) * 2003-04-11 2004-10-14 Kenneth Eliasen Implantable vascular access device
ES2737835T3 (en) 2003-04-23 2020-01-16 Valeritas Inc Hydraulically driven pump for long-term medication administration
US6926694B2 (en) * 2003-05-09 2005-08-09 Medsolve Technologies, Llc Apparatus and method for delivery of therapeutic and/or diagnostic agents
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US7192413B2 (en) * 2003-06-11 2007-03-20 Codman & Shurtleff, Inc. Needle guard having inherent probe directing features
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
USD902408S1 (en) 2003-11-05 2020-11-17 Abbott Diabetes Care Inc. Analyte sensor control unit
US7494481B2 (en) * 2004-12-03 2009-02-24 Medtronic Minimed, Inc. Multi-position infusion set device and process
US7699808B2 (en) * 2003-11-10 2010-04-20 Smiths Medical Asd, Inc. Subcutaneous infusion device and method
US7850658B2 (en) * 2003-11-10 2010-12-14 Smiths Medical Asd, Inc. Subcutaneous infusion device and method including release feature for adhesive portion
US7699807B2 (en) * 2003-11-10 2010-04-20 Smiths Medical Asd, Inc. Device and method for insertion of a cannula of an infusion device
US7731691B2 (en) * 2003-11-10 2010-06-08 Smiths Medical Asd, Inc. Subcutaneous infusion device and device for insertion of a cannula of an infusion device and method
US7309326B2 (en) * 2003-11-18 2007-12-18 Icu Medical, Inc. Infusion set
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US9241735B2 (en) * 2003-12-05 2016-01-26 Onset Medical Corporation Expandable percutaneous sheath
US7780692B2 (en) * 2003-12-05 2010-08-24 Onset Medical Corporation Expandable percutaneous sheath
US7108678B2 (en) * 2003-12-31 2006-09-19 Biotop Holding Co., Ltd. Captive cover for a hypodermic needle of an intravenous (IV) tube assembly
CA2556331A1 (en) 2004-02-17 2005-09-29 Therasense, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
ES2323793T3 (en) 2004-03-26 2009-07-24 Unomedical A/S INFUSION SET
EP1768724A4 (en) * 2004-06-07 2010-08-25 Bard Inc C R Subcutaneous infusion devices
US7585287B2 (en) * 2004-06-16 2009-09-08 Smiths Medical Md, Inc. Device and method for insertion of a cannula of an infusion device
WO2006014425A1 (en) 2004-07-02 2006-02-09 Biovalve Technologies, Inc. Methods and devices for delivering glp-1 and uses thereof
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
DE502004002772D1 (en) * 2004-07-15 2007-03-15 Clinico Gmbh Puncture arrangement with flexible retention tube for connection to a medical supply line
MX2007000768A (en) * 2004-07-21 2007-04-02 Animas Corp Method and systems for providing an infusion device interface.
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
DE102004039408A1 (en) * 2004-08-13 2006-03-02 Disetronic Licensing Ag Insertion head for medical or pharmaceutical applications
US20060100581A1 (en) * 2004-08-13 2006-05-11 Mogensen Lasse W Reservoir for front end loaded infusion device
EP1819391B1 (en) * 2004-09-09 2020-02-19 Onset Medical Corporation Expandable transluminal sheath
US7892203B2 (en) * 2004-09-09 2011-02-22 Onset Medical Corporation Expandable transluminal sheath
US7905857B2 (en) 2005-07-11 2011-03-15 Covidien Ag Needle assembly including obturator with safety reset
US7850650B2 (en) * 2005-07-11 2010-12-14 Covidien Ag Needle safety shield with reset
US7828773B2 (en) 2005-07-11 2010-11-09 Covidien Ag Safety reset key and needle assembly
DE202004017861U1 (en) * 2004-11-17 2005-02-17 Clinico Gmbh Extraction device for the protected extraction of a flexible puncture needle from a catheter, in particular a catheter with flexible retention tube
US7303543B1 (en) * 2004-12-03 2007-12-04 Medtronic Minimed, Inc. Medication infusion set
US7867200B2 (en) 2004-12-10 2011-01-11 Unomedical A/S Inserter
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
EP1683543B1 (en) * 2005-01-19 2008-10-15 Möller Medical GmbH & Co.KG System for cannula hub and base
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US7704229B2 (en) 2005-02-03 2010-04-27 Medtronic Minimed, Inc. Insertion device
US8299025B2 (en) 2005-02-03 2012-10-30 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US20060184104A1 (en) * 2005-02-15 2006-08-17 Medtronic Minimed, Inc. Needle guard
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
MX2007011338A (en) * 2005-03-21 2007-11-09 Unomedical As A mounting pad, an adhesive device comprising such mounting pad, and methods of applying such devices to a patient.
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US20060276747A1 (en) 2005-06-06 2006-12-07 Sherwood Services Ag Needle assembly with removable depth stop
US7780723B2 (en) 2005-06-13 2010-08-24 Edwards Lifesciences Corporation Heart valve delivery system
US7621395B2 (en) * 2005-06-28 2009-11-24 Unomedical A/S Packing for infusion set and method of applying an infusion set
US7731692B2 (en) * 2005-07-11 2010-06-08 Covidien Ag Device for shielding a sharp tip of a cannula and method of using the same
US8603034B2 (en) * 2005-07-12 2013-12-10 Applied Diabetes Research, Inc. One piece sealing reservoir for an insulin infusion pump
RU2440831C2 (en) * 2005-08-22 2012-01-27 Паттон Медикал Дивайсиз, Лп Devices, systems and methods of liquid introduction
DK1762259T3 (en) 2005-09-12 2011-01-03 Unomedical As Infusion set insertion device with a first and a second spring assembly
US9144645B2 (en) * 2005-09-21 2015-09-29 Applied Diabetes Research, Inc. One piece sealing reservoir for an insulin infusion pump
US8852164B2 (en) 2006-02-09 2014-10-07 Deka Products Limited Partnership Method and system for shape-memory alloy wire control
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
IL178557A0 (en) * 2005-10-19 2007-02-11 Animas Corp Safety infusion set
US8226614B2 (en) 2005-11-03 2012-07-24 Patton Medical Devices, Lp Fluid delivery devices, systems and methods
US7654735B2 (en) 2005-11-03 2010-02-02 Covidien Ag Electronic thermometer
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
EP1962925B1 (en) 2005-12-23 2009-04-22 Unomedical A/S Device for administration
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
CA2636034A1 (en) 2005-12-28 2007-10-25 Abbott Diabetes Care Inc. Medical device insertion
US11026822B2 (en) 2006-01-13 2021-06-08 C. R. Bard, Inc. Stent delivery system
CA2936205C (en) 2006-01-13 2018-08-21 C.R. Bard, Inc. Stent delivery system
US7931615B2 (en) * 2006-02-07 2011-04-26 Icu Medical, Inc. Infusion set
US11364335B2 (en) 2006-02-09 2022-06-21 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
EP3165247B1 (en) 2006-02-09 2020-10-28 DEKA Products Limited Partnership Pumping fluid delivery systems and methods using force application assembley
US11497846B2 (en) 2006-02-09 2022-11-15 Deka Products Limited Partnership Patch-sized fluid delivery systems and methods
US11478623B2 (en) 2006-02-09 2022-10-25 Deka Products Limited Partnership Infusion pump assembly
US20090218243A1 (en) * 2006-02-13 2009-09-03 Unomedical A/S Packing for Injection Device
US20070191772A1 (en) * 2006-02-16 2007-08-16 Animas Corporation Straight insertion safety infusion set
US20070191773A1 (en) * 2006-02-16 2007-08-16 Animas Corporation Low profile infusion set
KR20080104342A (en) 2006-02-28 2008-12-02 우노메디컬 에이/에스 Inserter for infusion part and infusion part provided with needle protector
JP2009532117A (en) 2006-03-30 2009-09-10 ヴァレリタス,エルエルシー Multi-cartridge fluid dispensing device
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US20070255126A1 (en) 2006-04-28 2007-11-01 Moberg Sheldon B Data communication in networked fluid infusion systems
US7920907B2 (en) 2006-06-07 2011-04-05 Abbott Diabetes Care Inc. Analyte monitoring system and method
US8439838B2 (en) 2006-06-07 2013-05-14 Unomedical A/S Inserter for transcutaneous sensor
BRPI0712361A2 (en) 2006-06-09 2012-06-19 Unomedical As mounting bracket
CA2658577A1 (en) 2006-08-02 2008-02-07 Unomedical A/S Cannula and delivery device
GB0615658D0 (en) 2006-08-07 2006-09-13 Angiomed Ag Hand-held actuator device
EP2363112B8 (en) 2006-08-09 2018-11-21 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
US7993306B2 (en) * 2006-10-31 2011-08-09 Smiths Medical Asd, Inc. Subcutaneous infusion device and method including tapered cannula
EP1917990A1 (en) 2006-10-31 2008-05-07 Unomedical A/S Infusion set
US10154804B2 (en) * 2007-01-31 2018-12-18 Medtronic Minimed, Inc. Model predictive method and system for controlling and supervising insulin infusion
MX2009008001A (en) * 2007-02-02 2009-08-07 Unomedical As A gateway device.
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
DK1970084T3 (en) * 2007-03-14 2010-11-22 Hoffmann La Roche Insertion apparatus for an insertion head, especially for an infusion set
DE502007005457D1 (en) * 2007-03-14 2010-12-09 Roche Diagnostics Gmbh Insertion head for medical or pharmaceutical applications
ES2911529T3 (en) * 2007-05-07 2022-05-19 Unomedical As supply device
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
WO2008150917A1 (en) 2007-05-31 2008-12-11 Abbott Diabetes Care, Inc. Insertion devices and methods
EP2150195B1 (en) * 2007-06-06 2010-08-18 Unomedical A/S Packing allowing gas sterilisation
JP2010530266A (en) 2007-06-20 2010-09-09 ウノメディカル アクティーゼルスカブ Catheter and catheter manufacturing method and apparatus
WO2008155377A1 (en) * 2007-06-20 2008-12-24 Unomedical A/S Cannula insertion device with automatic needle retraction comprising only one spring
JP2010531692A (en) 2007-07-03 2010-09-30 ウノメディカル アクティーゼルスカブ Inserter with bistable equilibrium
AU2008274311A1 (en) 2007-07-10 2009-01-15 Unomedical A/S Inserter having two springs
GB0713497D0 (en) 2007-07-11 2007-08-22 Angiomed Ag Device for catheter sheath retraction
KR20100049576A (en) 2007-07-18 2010-05-12 우노메디컬 에이/에스 Insertion device with pivoting action
WO2009045622A1 (en) * 2007-08-10 2009-04-09 Medi-Life Cards, Llc Method and apparatus for auto injection of a therapeutic
DE102007049446A1 (en) 2007-10-16 2009-04-23 Cequr Aps Catheter introducer
US8357104B2 (en) 2007-11-01 2013-01-22 Coviden Lp Active stylet safety shield
WO2009067661A1 (en) * 2007-11-21 2009-05-28 Becton, Dickinson And Company Stylet handle attachment device
ES2788079T3 (en) * 2007-11-21 2020-10-20 Becton Dickinson Co Needle safety device
AU2008326336B2 (en) * 2007-11-21 2013-11-28 Becton, Dickinson And Company Safety needle guard
CN104874047B (en) 2007-12-31 2019-05-28 德卡产品有限公司 It is transfused pump assembly
US8414563B2 (en) 2007-12-31 2013-04-09 Deka Products Limited Partnership Pump assembly with switch
US8900188B2 (en) 2007-12-31 2014-12-02 Deka Products Limited Partnership Split ring resonator antenna adapted for use in wirelessly controlled medical device
US8881774B2 (en) 2007-12-31 2014-11-11 Deka Research & Development Corp. Apparatus, system and method for fluid delivery
US9456955B2 (en) 2007-12-31 2016-10-04 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US10188787B2 (en) 2007-12-31 2019-01-29 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US10080704B2 (en) 2007-12-31 2018-09-25 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US8323251B2 (en) 2008-01-14 2012-12-04 Fenwal, Inc. Phlebotomy needle assembly and frangible cover
CA2711772A1 (en) * 2008-02-08 2009-08-13 Unomedical A/S Inserter assembly
US20090204077A1 (en) * 2008-02-13 2009-08-13 Hasted Soren B Moulded Connection Between Cannula and Delivery Part
WO2009098291A1 (en) * 2008-02-08 2009-08-13 Unomedical A/S Assembly comprising inserter, cannula part and base part
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US10898643B2 (en) 2008-02-13 2021-01-26 Unomedical A/S Sealing between a cannula part and a fluid path
CA2715667A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
CA2715144A1 (en) * 2008-02-25 2009-09-03 Unomedical A/S Bubble shaped membrane and use of such membrane in a device
EP2110149B1 (en) * 2008-03-28 2017-05-03 Fenwal, Inc. Winged needle assembly and frangible cover
US9295786B2 (en) * 2008-05-28 2016-03-29 Medtronic Minimed, Inc. Needle protective device for subcutaneous sensors
MX2010014258A (en) * 2008-07-07 2011-03-21 Unomedical As Inserter for transcutaneous device.
US20100057021A1 (en) 2008-08-29 2010-03-04 Kohzo Ishikura Subcutaneous infusion device
CA3132517A1 (en) 2008-09-15 2010-03-18 Deka Products Limited Partnership Systems and methods for fluid delivery
BRPI0919548A2 (en) * 2008-09-29 2015-12-08 Unomedical As insert package
US8262616B2 (en) 2008-10-10 2012-09-11 Deka Products Limited Partnership Infusion pump assembly
US8016789B2 (en) 2008-10-10 2011-09-13 Deka Products Limited Partnership Pump assembly with a removable cover assembly
US8267892B2 (en) 2008-10-10 2012-09-18 Deka Products Limited Partnership Multi-language / multi-processor infusion pump assembly
US8223028B2 (en) 2008-10-10 2012-07-17 Deka Products Limited Partnership Occlusion detection system and method
US8708376B2 (en) 2008-10-10 2014-04-29 Deka Products Limited Partnership Medium connector
US8066672B2 (en) 2008-10-10 2011-11-29 Deka Products Limited Partnership Infusion pump assembly with a backup power supply
US7951110B2 (en) 2008-11-10 2011-05-31 Onset Medical Corporation Expandable spinal sheath and method of use
GB0821492D0 (en) * 2008-11-25 2008-12-31 Team Holdings Uk Ltd Integrated auto-injector cartridge system
AU2009331635A1 (en) 2008-12-22 2011-06-23 Unomedical A/S Medical device comprising adhesive pad
CA3149758A1 (en) 2009-01-12 2010-07-15 Becton, Dickinson And Company Infusion set and/or patch pump having at least one of an in-dwelling rigid catheter with flexible features and/or a flexible catheter attachment
US9375529B2 (en) 2009-09-02 2016-06-28 Becton, Dickinson And Company Extended use medical device
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US8807169B2 (en) 2009-02-12 2014-08-19 Picolife Technologies, Llc Flow control system for a micropump
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
CA2768011C (en) 2009-07-15 2018-07-24 Deka Products Limited Partnership Apparatus, systems and methods for an infusion pump assembly
US8939928B2 (en) 2009-07-23 2015-01-27 Becton, Dickinson And Company Medical device having capacitive coupling communication and energy harvesting
US8795309B2 (en) * 2009-07-29 2014-08-05 Smiths Medical Asd, Inc. Device for insertion of a cannula of an infusion device and method
JP2013500099A (en) 2009-07-30 2013-01-07 ウノメディカル・アー/エス Insertion device with horizontally movable member
US8641671B2 (en) 2009-07-30 2014-02-04 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US9533092B2 (en) 2009-08-07 2017-01-03 Unomedical A/S Base part for a medication delivery device
US8323249B2 (en) * 2009-08-14 2012-12-04 The Regents Of The University Of Michigan Integrated vascular delivery system
US8672873B2 (en) 2009-08-18 2014-03-18 Cequr Sa Medicine delivery device having detachable pressure sensing unit
US8547239B2 (en) * 2009-08-18 2013-10-01 Cequr Sa Methods for detecting failure states in a medicine delivery device
AU2010286917B2 (en) 2009-08-31 2016-03-10 Abbott Diabetes Care Inc. Medical devices and methods
EP2473098A4 (en) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc Analyte signal processing device and methods
EP2473099A4 (en) 2009-08-31 2015-01-14 Abbott Diabetes Care Inc Analyte monitoring system and methods for managing power and noise
US10092691B2 (en) 2009-09-02 2018-10-09 Becton, Dickinson And Company Flexible and conformal patch pump
US8298561B2 (en) 2009-09-28 2012-10-30 Intarcia Therapeutics, Inc. Rapid establishment and/or termination of substantial steady-state drug delivery
US9320461B2 (en) 2009-09-29 2016-04-26 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
US8343106B2 (en) * 2009-12-23 2013-01-01 Alcon Research, Ltd. Ophthalmic valved trocar vent
CN102665580B (en) 2009-12-23 2015-04-08 爱尔康研究有限公司 Ophthalmic valved trocar cannula
WO2011082370A1 (en) * 2009-12-31 2011-07-07 Abbott Diabetes Care Inc. Injection port device adapted for use with insulin pump
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
CN102548476A (en) 2010-03-24 2012-07-04 雅培糖尿病护理公司 Medical device inserters and processes of inserting and using medical devices
EP2552513B1 (en) 2010-03-30 2014-03-19 Unomedical A/S Medical device
WO2011146769A2 (en) 2010-05-19 2011-11-24 Tangent Medical Technologies Llc Integrated vascular delivery system
WO2011146772A1 (en) 2010-05-19 2011-11-24 Tangent Medical Technologies Llc Safety needle system operable with a medical device
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8915879B2 (en) 2010-09-24 2014-12-23 Perqflo, Llc Infusion pumps
EP2433663A1 (en) 2010-09-27 2012-03-28 Unomedical A/S Insertion system
EP2436412A1 (en) 2010-10-04 2012-04-04 Unomedical A/S A sprinkler cannula
GB201017834D0 (en) 2010-10-21 2010-12-01 Angiomed Ag System to deliver a bodily implant
US9211378B2 (en) 2010-10-22 2015-12-15 Cequr Sa Methods and systems for dosing a medicament
US8905972B2 (en) 2010-11-20 2014-12-09 Perqflo, Llc Infusion pumps
US9950109B2 (en) 2010-11-30 2018-04-24 Becton, Dickinson And Company Slide-activated angled inserter and cantilevered ballistic insertion for intradermal drug infusion
US8795230B2 (en) 2010-11-30 2014-08-05 Becton, Dickinson And Company Adjustable height needle infusion device
US8814831B2 (en) 2010-11-30 2014-08-26 Becton, Dickinson And Company Ballistic microneedle infusion device
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
CN103957962B (en) 2011-10-05 2017-07-07 犹诺医药有限公司 Insert for inserting multiple percutaneous parts simultaneously
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
JP6443802B2 (en) 2011-11-07 2018-12-26 アボット ダイアベティス ケア インコーポレイテッドAbbott Diabetes Care Inc. Analyte monitoring apparatus and method
US8790307B2 (en) 2011-12-01 2014-07-29 Picolife Technologies, Llc Drug delivery device and methods therefor
US8771229B2 (en) 2011-12-01 2014-07-08 Picolife Technologies, Llc Cartridge system for delivery of medicament
EP2902054B1 (en) 2011-12-07 2018-02-07 Becton, Dickinson and Company Needle shielding assemblies and infusion devices for use therewith
CA3043590C (en) 2011-12-07 2021-10-19 Becton, Dickinson And Company Infusion device with releasable fluid connector
FI4056105T3 (en) 2011-12-11 2023-12-28 Abbott Diabetes Care Inc Analyte sensor devices
US9610401B2 (en) * 2012-01-13 2017-04-04 Medtronic Minimed, Inc. Infusion set component with modular fluid channel element
US11524151B2 (en) 2012-03-07 2022-12-13 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US10130759B2 (en) 2012-03-09 2018-11-20 Picolife Technologies, Llc Multi-ported drug delivery device having multi-reservoir cartridge system
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US10245420B2 (en) 2012-06-26 2019-04-02 PicoLife Technologies Medicament distribution systems and related methods of use
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US9731069B2 (en) 2012-09-27 2017-08-15 Becton, Dickinson And Company Perpendicular infusion set and disposable inserter
USD747459S1 (en) 2012-12-07 2016-01-12 Becton, Dickinson And Company Infusion set assembly
USD747456S1 (en) 2012-12-07 2016-01-12 Becton, Dickinson And Company Infusion set assembly
USD754842S1 (en) 2012-12-07 2016-04-26 Becton, Dickinson And Company Infusion set needle guard
USD754843S1 (en) 2012-12-07 2016-04-26 Becton, Dickinson And Company Infusion set assembly
USD747458S1 (en) 2012-12-07 2016-01-12 Becton, Dickinson And Company Infusion set insertion needle assembly
USD756504S1 (en) 2012-12-07 2016-05-17 Becton, Dickinson And Company Infusion set base
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9889252B2 (en) * 2013-06-14 2018-02-13 Medtronic, Inc. Infusion device assembly
EP4309699A2 (en) 2013-07-03 2024-01-24 DEKA Products Limited Partnership Apparatus and system for fluid delivery
US8956328B2 (en) 2013-07-18 2015-02-17 Luther Needlesafe Products, Inc. Low profile passive protector for an I.V. catheter
US10279105B2 (en) 2013-12-26 2019-05-07 Tandem Diabetes Care, Inc. System and method for modifying medicament delivery parameters after a site change
AU2015214400B2 (en) 2014-02-04 2019-10-03 Icu Medical, Inc. Self-priming systems and methods
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10265506B2 (en) * 2015-02-02 2019-04-23 Quick Snap Medical Supply, LLC Vascular access devices and methods
EP3258989B1 (en) 2015-02-18 2020-01-01 Medtronic Minimed, Inc. Ambulatory infusion pump with static and dynamic seals
US10674944B2 (en) 2015-05-14 2020-06-09 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
CA2985191C (en) * 2015-05-15 2023-08-15 Merit Medical Systems, Inc. Quick-release hubs for medical devices
EP3302354B1 (en) * 2015-06-03 2023-10-04 i2o Therapeutics, Inc. Implant placement systems
EP3413954A1 (en) 2016-02-12 2018-12-19 Perqflo, LLC Ambulatory infusion pumps and assemblies for use with same
MX2018009915A (en) * 2016-02-16 2019-02-07 Deka Products Lp Infusion set and inserter assembly.
EP3448491A4 (en) 2016-04-29 2020-01-08 Smiths Medical ASD, Inc. Subcutaneous insertion systems, devices and related methods
CN109310743A (en) 2016-05-16 2019-02-05 因塔西亚制药公司 Glucagon receptor selectivity polypeptide and its application method
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CA3033266A1 (en) * 2016-09-15 2018-03-22 Becton, Dickinson And Company Needle hub for subcutaneous infusion set
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
WO2018136898A1 (en) 2017-01-23 2018-07-26 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
WO2018184012A1 (en) 2017-03-31 2018-10-04 Capillary Biomedical, Inc. Helical insertion infusion device
CA3061913C (en) * 2017-05-08 2022-05-31 Medtronic Minimed, Inc. Flexible tubing, cannula and insertion needle
US11260171B2 (en) 2017-07-04 2022-03-01 Medtronic Minimed, Inc. Ambulatory infusion pumps and assemblies for use with same
EP3784312A1 (en) 2018-04-24 2021-03-03 DEKA Products Limited Partnership Apparatus and system for fluid delivery
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
US10820933B1 (en) 2019-07-15 2020-11-03 Osteon Medical LLC Kyphoplasty system and method
CN114585399A (en) * 2019-10-02 2022-06-03 欧赛特有限公司 Device for quick attachment of biomedical devices
CN110975061B (en) * 2019-11-19 2021-09-10 山东省千佛山医院 Puncture-preventing remaining needle capable of continuously supplying liquid
US11565084B2 (en) * 2020-05-01 2023-01-31 Np Medical Inc. Low profile catheter system
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
US11752306B2 (en) 2021-01-22 2023-09-12 Luther Needlesafe Products, Llc Low profile passive protector for an I.V. catheter
USD979746S1 (en) 2021-02-26 2023-02-28 Luther Needlesafe Products, Llc Over-the-needle catheter insertion device
US11903628B1 (en) 2023-04-20 2024-02-20 Osteon Medical LLC Kyphoplasty system and method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2242114A1 (en) * 1973-08-31 1975-03-28 Mpl Inc Injection needle assembly - with bandage acting as a handle and as a cover for the injection puncture
US3973565A (en) * 1973-07-20 1976-08-10 Everett Medical Products Limited Winged cannula with skin securing means
US4755173A (en) * 1986-02-25 1988-07-05 Pacesetter Infusion, Ltd. Soft cannula subcutaneous injection set
DE29503099U1 (en) * 1995-02-24 1995-04-13 Frick Norman Permanent cannula, especially for subcutaneous infusion
US5522803A (en) * 1993-03-09 1996-06-04 Pharma Plast International A/S Infusion set for an intermittent or continuous administration of a therapeutical substance
WO1998058693A1 (en) * 1997-06-20 1998-12-30 Maersk Medical A/S Subcutaneous infusion set

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4245635A (en) * 1979-01-29 1981-01-20 Jelco Laboratories Catheter assembly for intermittent intravenous use
US4573994A (en) 1979-04-27 1986-03-04 The Johns Hopkins University Refillable medication infusion apparatus
US4685903A (en) 1984-01-06 1987-08-11 Pacesetter Infusion, Ltd. External infusion pump apparatus
US4678408A (en) 1984-01-06 1987-07-07 Pacesetter Infusion, Ltd. Solenoid drive apparatus for an external infusion pump
US4562751A (en) 1984-01-06 1986-01-07 Nason Clyde K Solenoid drive apparatus for an external infusion pump
US4950252A (en) * 1987-11-02 1990-08-21 Luther Medical Products, Inc. Single hand actuated locking safety catheter and method of use
US4880412A (en) * 1988-02-09 1989-11-14 Sol Weiss Tube insertion apparatus
US5097122A (en) 1990-04-16 1992-03-17 Pacesetter Infusion, Ltd. Medication infusion system having optical motion sensor to detect drive mechanism malfunction
US5080653A (en) 1990-04-16 1992-01-14 Pacesetter Infusion, Ltd. Infusion pump with dual position syringe locator
US5176662A (en) 1990-08-23 1993-01-05 Minimed Technologies, Ltd. Subcutaneous injection set with improved cannula mounting arrangement
US5201717A (en) * 1990-12-05 1993-04-13 Philip Wyatt Safety enclosure
DE4211932C1 (en) * 1992-04-09 1993-04-29 Erika 4290 Bocholt De Willing
US5267967A (en) * 1992-06-08 1993-12-07 Hollister Incorporated Retention device
US5299571A (en) 1993-01-22 1994-04-05 Eli Lilly And Company Apparatus and method for implantation of sensors
US5257980A (en) 1993-04-05 1993-11-02 Minimed Technologies, Ltd. Subcutaneous injection set with crimp-free soft cannula
DE724461T1 (en) * 1993-09-27 1997-02-13 Eastland Tech Australia An infusion set
US5423775A (en) * 1994-01-21 1995-06-13 Winfield Industries Locking connector assembly
US5390671A (en) 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
US5391250A (en) 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
US5482473A (en) 1994-05-09 1996-01-09 Minimed Inc. Flex circuit connector
US5568806A (en) 1995-02-16 1996-10-29 Minimed Inc. Transcutaneous sensor insertion set
US5647853A (en) 1995-03-03 1997-07-15 Minimed Inc. Rapid response occlusion detector for a medication infusion pump
US5584813A (en) * 1995-06-07 1996-12-17 Minimed Inc. Subcutaneous injection set
US5728071A (en) * 1996-09-09 1998-03-17 Watson; Robert L. Injection patch

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3973565A (en) * 1973-07-20 1976-08-10 Everett Medical Products Limited Winged cannula with skin securing means
FR2242114A1 (en) * 1973-08-31 1975-03-28 Mpl Inc Injection needle assembly - with bandage acting as a handle and as a cover for the injection puncture
US4755173A (en) * 1986-02-25 1988-07-05 Pacesetter Infusion, Ltd. Soft cannula subcutaneous injection set
US5522803A (en) * 1993-03-09 1996-06-04 Pharma Plast International A/S Infusion set for an intermittent or continuous administration of a therapeutical substance
DE29503099U1 (en) * 1995-02-24 1995-04-13 Frick Norman Permanent cannula, especially for subcutaneous infusion
WO1998058693A1 (en) * 1997-06-20 1998-12-30 Maersk Medical A/S Subcutaneous infusion set

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001052617A3 (en) * 2000-01-18 2002-02-28 Sterling Medivations Inc Subcutaneous injection set for use with a reservoir that has a septum
WO2001052617A2 (en) * 2000-01-18 2001-07-26 Sterling Medivations, Inc. Subcutaneous injection set for use with a reservoir that has a septum
US6749589B1 (en) 2000-01-18 2004-06-15 Sterling Medications, Inc. Subcutaneous injection set for use with a reservoir that has a septum
EP1368080A4 (en) * 2001-03-04 2007-08-15 Sterling Medivations Inc Infusion hub assembly and fluid line disconnect system
JP2009240814A (en) * 2001-03-04 2009-10-22 Icu Medical Inc Infusion hub assembly and fluid line disconnect system
EP1368080A2 (en) * 2001-03-04 2003-12-10 Sterling Medivations, Inc. Infusion hub assembly and fluid line disconnect system
US6685674B2 (en) 2001-03-04 2004-02-03 Sterling Medivations, Inc. Infusion hub assembly and fluid line disconnect system
WO2002094352A3 (en) * 2001-05-18 2003-05-08 Deka Products Lp Infusion set for a fluid pump
EP1815879A2 (en) * 2001-05-18 2007-08-08 Deka Products Limited Partnership Infusion set for a fluid pump
US9173996B2 (en) 2001-05-18 2015-11-03 Deka Products Limited Partnership Infusion set for a fluid pump
EP1815879A3 (en) * 2001-05-18 2007-11-14 Deka Products Limited Partnership Infusion set for a fluid pump
WO2002094352A2 (en) * 2001-05-18 2002-11-28 Deka Products Limited Partnership Infusion set for a fluid pump
US7306578B2 (en) 2002-01-04 2007-12-11 Deka Products Limited Partnership Loading mechanism for infusion pump
US7517335B2 (en) 2002-02-18 2009-04-14 Cequr Aps Device for administering of medication in fluid form
EP1839699A1 (en) * 2004-12-22 2007-10-03 Terumo Kabushiki Kaisha Connector, tube assembly, infusion tube set, and container for medical use
EP1839699A4 (en) * 2004-12-22 2008-03-19 Terumo Corp Connector, tube assembly, infusion tube set, and container for medical use
GB2450781B (en) * 2007-07-06 2009-09-02 Applied Medical Technology Ltd Tube connector
GB2450781A (en) * 2007-07-06 2009-01-07 Applied Medical Technology Ltd Connector with shielded needle for connecting a tube to an infusion device
US9180245B2 (en) 2008-10-10 2015-11-10 Deka Products Limited Partnership System and method for administering an infusible fluid
WO2011112331A1 (en) * 2010-03-10 2011-09-15 Becton, Dickinson And Company Catheter device with hooding feature
CN102791320A (en) * 2010-03-10 2012-11-21 贝克顿·迪金森公司 Catheter device with hooding feature
AU2011224785B2 (en) * 2010-03-10 2016-03-10 Becton, Dickinson And Company Catheter device with hooding feature
AU2016203620B2 (en) * 2010-03-10 2017-07-06 Becton, Dickinson And Company Catheter device with hooding feature
WO2017211493A1 (en) * 2016-06-10 2017-12-14 Fresenius Kabi Deutschland Gmbh Cannulation device
US10945760B2 (en) 2016-06-10 2021-03-16 Fresenius Kabi Deutschland Gmbh Cannulation device
WO2018186964A3 (en) * 2017-04-07 2019-01-17 Becton, Dickinson And Company Low-profile extension for a catheter assembly
US11116936B2 (en) 2017-04-07 2021-09-14 Becton, Dickinson And Company Low-profile extension for a catheter assembly
EP4137175A1 (en) * 2021-08-18 2023-02-22 Medtronic MiniMed, Inc. Infusion set with rotatable hub and process

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US6520938B1 (en) 2003-02-18
AU3068599A (en) 1999-09-20
EP1223997B1 (en) 2008-12-31
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WO1999044655A3 (en) 1999-10-28
DK1223997T3 (en) 2009-03-30
DE69940222D1 (en) 2009-02-12

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